Electrical capacitance tomography(ECT)has been applied to two-phase flow measurement in recent years.Image reconstruction algorithms play an important role in the successful applications of ECT.To solve the ill-posed ...Electrical capacitance tomography(ECT)has been applied to two-phase flow measurement in recent years.Image reconstruction algorithms play an important role in the successful applications of ECT.To solve the ill-posed and nonlinear inverse problem of ECT image reconstruction,a new ECT image reconstruction method based on fast linearized alternating direction method of multipliers(FLADMM)is proposed in this paper.On the basis of theoretical analysis of compressed sensing(CS),the data acquisition of ECT is regarded as a linear measurement process of permittivity distribution signal of pipe section.A new measurement matrix is designed and L1 regularization method is used to convert ECT inverse problem to a convex relaxation problem which contains prior knowledge.A new fast alternating direction method of multipliers which contained linearized idea is employed to minimize the objective function.Simulation data and experimental results indicate that compared with other methods,the quality and speed of reconstructed images are markedly improved.Also,the dynamic experimental results indicate that the proposed algorithm can ful fill the real-time requirement of ECT systems in the application.展开更多
A fiber Bragg grating (FBG) geophone and a surface seismic wave-based algorithm for detecting the direction of arrival (DOA) are described. The operational principle of FBG geophone is introduced and illustrated with ...A fiber Bragg grating (FBG) geophone and a surface seismic wave-based algorithm for detecting the direction of arrival (DOA) are described. The operational principle of FBG geophone is introduced and illustrated with systematic experimental data, demonstrating an improved FBG geophone with many advantages over the conventional geophones. An innovative, robust, and simple algorithm is developed for obtaining the bearing information on the seismic events, such as people walking, or vehicles moving. Such DOA estimate is based on the interactions and projections of surface-propagating seismic waves generated by the moving personnel or vehicles with a single tri-axial seismic sensor based on FBGs. Of particular interest is the case when the distance between the source of the seismic wave and the detector is less than or comparable to one wavelength (less than 100 m), corresponding to near-field detection, where an effective method of DOA finding lacks.展开更多
Fiber-based curvature sensors,especially those capable of discerning the direction of curvature,have attracted more and more interest due to their promising applications in structural health monitoring,high-precision ...Fiber-based curvature sensors,especially those capable of discerning the direction of curvature,have attracted more and more interest due to their promising applications in structural health monitoring,high-precision measurement,medical and biological diagnosis-treat instruments,and so on.Here,we propose and demonstrate a compact directional curvature sensor that comprises two bridged waveguides and three Bragg gratings in a section of three-core fiber(TCF).Both the waveguides and gratings are integrated by femtosecond laser micromachining method.The waveguides,connecting the TCF outer cores to the lead-in single-mode fiber core,function as beam couplers to realize simultaneous interrogation of all three gratings without any separate fan-in/out component.Owing to the spatial specificity,the outer-core gratings exhibit high and direction-dependent sensitivity to curvature,whereas the central-core grating is nearly insensitive to curvature but shows similar sensitivities to ambient temperature and axial strain as the outer-core gratings.It can be used to compensate the cross impact of temperature and strain when the outer-core gratings are applied for curvature detection.Moreover,the wavelength interval between two outer-core gratings is also proposed as an indicator for curvature sensing.It features with a much higher sensitivity to curvature and reduced sensitivities to temperature and axial strain.The corresponding maximum sensitivity to curvature is as high as 191.89 pm/m-1,while the sensitivities to temperature and strain are only 0.3 pm/℃and 0.0218 pm/με,respectively.Therefore,our proposed device provides a compact and robust all-infiber solution for directional curvature sensing.It not only offers high sensitivity and accuracy but also immunity to temperature and axial strain fluctuations,making it a promising tool for a wide range of applications.展开更多
It is found that when the parity–time symmetry phenomenon is introduced into the resonant optical gyro system and it works near the exceptional point,the sensitivity can in theory be significantly amplified at low an...It is found that when the parity–time symmetry phenomenon is introduced into the resonant optical gyro system and it works near the exceptional point,the sensitivity can in theory be significantly amplified at low angular rate.However,in fact,the exceptional point is easily disturbed by external environmental variables,which means that it depends on harsh experimental environment and strong control ability,so it is difficult to move towards practical application.Here,we propose a new angular rate sensor structure based on exceptional surface,which has the advantages of high sensitivity and high robustness.The system consists of two fiber-optic ring resonators and two optical loop mirrors,and one of the resonators contains a variable ratio coupler and a variable optical attenuator.We theoretically analyze the system response,and the effects of phase and coupling ratio on the system response.Finally,compared with the conventional resonant gyro,the sensitivity of this exceptional surface angular rate sensor can be improved by about 300 times at low speed.In addition,by changing the loss coefficient in the ring resonator,we can achieve a wide range of 600 rad/s.This scheme provides a new approach for the development of ultra-high sensitivity and wide range angular rate sensors in the future.展开更多
With the extensive application of large-scale array antennas,the increasing number of array elements leads to the increasing dimension of received signals,making it difficult to meet the real-time requirement of direc...With the extensive application of large-scale array antennas,the increasing number of array elements leads to the increasing dimension of received signals,making it difficult to meet the real-time requirement of direction of arrival(DOA)estimation due to the computational complexity of algorithms.Traditional subspace algorithms require estimation of the covariance matrix,which has high computational complexity and is prone to producing spurious peaks.In order to reduce the computational complexity of DOA estimation algorithms and improve their estimation accuracy under large array elements,this paper proposes a DOA estimation method based on Krylov subspace and weighted l_(1)-norm.The method uses the multistage Wiener filter(MSWF)iteration to solve the basis of the Krylov subspace as an estimate of the signal subspace,further uses the measurement matrix to reduce the dimensionality of the signal subspace observation,constructs a weighted matrix,and combines the sparse reconstruction to establish a convex optimization function based on the residual sum of squares and weighted l_(1)-norm to solve the target DOA.Simulation results show that the proposed method has high resolution under large array conditions,effectively suppresses spurious peaks,reduces computational complexity,and has good robustness for low signal to noise ratio(SNR)environment.展开更多
Introduction and Invitation DICP Symposium is a special series of interna-tional conference named after the Dalian Instituteof Chemical Physics (DICP). The DICP Symposiumwas founded with the purpose to promote the int...Introduction and Invitation DICP Symposium is a special series of interna-tional conference named after the Dalian Instituteof Chemical Physics (DICP). The DICP Symposiumwas founded with the purpose to promote the interna-tional communication and collaboration between theDICP and the international scientific community, to展开更多
The Liaoji Proterozoic rift is an inter-intracontinenatl rift developed from Archean granite-greenstone tectonic regime and contains many important mineral deposits of U, B, magnesite, Pb-Zn, Au, Ag, Co and P. These d...The Liaoji Proterozoic rift is an inter-intracontinenatl rift developed from Archean granite-greenstone tectonic regime and contains many important mineral deposits of U, B, magnesite, Pb-Zn, Au, Ag, Co and P. These deposits were formed as the result of late mobilization, transportation and concentfation of the previously enriched ore-forming mate- rials in several ore-bearing formations formed during the rift stage. So the metallogeny of these deposits in the rift shows both inheritance and new generation of the ore-forming materials. In future ore-searching practice, attentions should be paid on the studies of the ore-bearing formations in the rift, on the multiple stages of metallogeny and and on multiple derivations of the ore-forming materials.展开更多
In order to improve the thermostability of β- 1,3-1,4-glucanase, evolutionary molecular engineering was used to evolve the β-1,3-1,4-glucanase from Bacillus subtilis ZJF-1A5. The process involves random mutation by ...In order to improve the thermostability of β- 1,3-1,4-glucanase, evolutionary molecular engineering was used to evolve the β-1,3-1,4-glucanase from Bacillus subtilis ZJF-1A5. The process involves random mutation by error-prone PCR and DNA shuffling followed by screening on the filter-based assay. Two mutants, EGsl and EGs2, were found to have four and five amino acid substitutions, respectively. These substitutions resulted in an increase in melting temperature from Tm=62.5℃ for the wild-type enzyme to Tm=65.5℃ for the mutant EGsl and 67.5℃ for the mutant EGs2. However, the two mutated enzymes had opposite approaches to produce reducing sugar from lichenin with either much higher (28%) for the former or much lower (21.6%) for the latter in comparison with their parental enzymes. The results demonstrate that directed evolution is an effective approach to improve the thermostability of a mesophilic enzyme.展开更多
AIM: To investigate the molecular mechanisms involved in coagulation factor expression and/or function during direct hyperplasia (DH)-mediated liver regeneration. METHODS: Direct hyperplasia-mediated liver regener...AIM: To investigate the molecular mechanisms involved in coagulation factor expression and/or function during direct hyperplasia (DH)-mediated liver regeneration. METHODS: Direct hyperplasia-mediated liver regeneration was induced in female C57BL/6 mice by administering 1,4-bisr2-(3,5-dichloropyridyloxy)] benzene (TCPOBOP), a representative hepatomitogen. Mice were weighed and sacrificed at various time points [Day 0 (D0: prior to injection), 3 h, D1, D2, D3, and D10] after TCPOBOP administration to obtain liver and blood samples. Using the RNA samples extracted from the liver, a comprehensive analysis was performed on the hepatic gene expression profiling of coagulation-related factors by real-time RT-PCR (fibrinogen, prothrombin, factors Ⅴ, Ⅶ, Ⅷ, Ⅸ, Ⅹ, Ⅺ, Ⅻ, ⅩⅢβ , plasminogen, antithrombin, protein C, protein S, ADAMTS13, and VWF). The corresponding plasma levels of coagulation factors (fibrinogen, prothrombin, factors Ⅴ, Ⅶ, Ⅷ, Ⅸ, Ⅹ, Ⅺ, Ⅻ, ⅩⅢ, and VWF) were also analyzed and compared with their mRNA levels. RESULTS: Gavage administration of TCPOBOP (3 mg/kg body weight) resulted in a marked and gradual increase in the weight of the mouse livers relative to the total body weight to 220% by D10 relative to the DO (control) ratios. At the peak of liver regeneration (D1 and D2), the gene expression levels for most of the coagulationrelated factors (fibrinogen, prothrombin, factors Ⅴ, Ⅶ, Ⅷ, Ⅸ,Ⅺ, Ⅻ, ⅩⅢβ, plasminogen, antithrombin, protein C, ADAMTS13, VWF) were found to be downregulated in a time-dependent manner, and gradually recovered by D10 to the basal levels. Only mRNA levels of factor X and protein S failed to show any decrease during the regenerative phase. As for the plasma levels, 5 clotting factors (prothrombin, factors Ⅷ, Ⅸ, Ⅺ, and Ⅻ) demonstrated a significant decrease (P 〈 0.05) during the regeneration phase compared with DO. Among these 5 factors, factor Ⅸ and factor Ⅺ showed the most dramatic decline in their activities by about 50% at D2 compared to the basal levels, and these reductions in plasma activity for both factors were consistent with our RT-PCR findings. In contrast, the plasma activities of the other coagulation factors (fibrinogen, factors Ⅴ, Ⅶ, ⅩⅢ, and VWF) were not significantly reduced, despite the reduction in the liver mRNA levels. Unlike the other factors, FX showed a temporal increase in its plasma activity, with significant increases (P 〈 0.05) detected at DI. CONCLUSION: Investigating the coagulation cascade protein profiles during liver regeneration by DH may help to better understand the basic biology of the liver under normal and pathological conditions.展开更多
针对典型感潮河网地区水环境污染日趋严重与洪涝灾害频发的问题,为优化河网水动力和降低河道漫溢风险,基于Info Works ICM(integrated catchment management)模型建立福州市仓山区龙津阳岐片区城市水文模型与一维河网水动力耦合模型,以2...针对典型感潮河网地区水环境污染日趋严重与洪涝灾害频发的问题,为优化河网水动力和降低河道漫溢风险,基于Info Works ICM(integrated catchment management)模型建立福州市仓山区龙津阳岐片区城市水文模型与一维河网水动力耦合模型,以2022年6月14日实测降雨及河道水位数据对模型参数进行校准,平均纳什效率系数为0.78,平均洪峰误差为1.5%。设计并模拟3种晴天工况和3种“卢碧”台风雨天工况,结果表明:晴天从无调控到工况3,随着引水量的增加,河网平均流速逐步增加,总体增加66.4%,河道水动力提升显著;雨天从原有调控工况到工况3,随着河道预降水位值增大,关键断面平均超警历时逐步减少,总体下降73%,河道漫溢风险明显降低。构建河网水文水动力耦合模型和工况优选,可为仓山区进一步提升河网水动力与城市汛期洪涝灾害防治能力的方案制定提供决策依据,也可为其他同类研究提供借鉴。展开更多
Measurements of wave heights with image sequences from a Charged Coupled Device(CCD) camera were made. Sinusoidal, as well as unidirectional and directional, waves were used for the experiments. A transfer function wa...Measurements of wave heights with image sequences from a Charged Coupled Device(CCD) camera were made. Sinusoidal, as well as unidirectional and directional, waves were used for the experiments. A transfer function was obtained by calibration of the magnitudes of the gray values of the images against the results of wave gauge measurements for directional waves. With this transfer function, wave heights for regular waves were deduced. It is shown that the average relative errors are smaller than 16% for both unidirectional and directional waves.展开更多
This paper proposes an adaptive sparsity-based direct position determination (DPD) appoach to locate multiple targets in the case of time-varying channels. The novel feature of this method is to dynamically adjust bot...This paper proposes an adaptive sparsity-based direct position determination (DPD) appoach to locate multiple targets in the case of time-varying channels. The novel feature of this method is to dynamically adjust both the overcomplete basis and the sparse solution based on a two-step dictionary learning (DL) framework. The method first performs supervised offline DL by using the quadratic programming approach, and then the dictionary is continuously updated in an incremental fashion to adapt to the time-varying channel during the online stage. Furthermore, the method does not need the number of emitters a prior. Simulation results demonstrate the performance of the proposed algorithm on the location estimation accuracy.展开更多
Direct carbon solid oxide fuel cells(DC-SOFCs)are promising,green,and efficient power-generating devices that are fueled by solid carbons and comprise all-solid-state structures.Developing suitable anode materials for...Direct carbon solid oxide fuel cells(DC-SOFCs)are promising,green,and efficient power-generating devices that are fueled by solid carbons and comprise all-solid-state structures.Developing suitable anode materials for DC-SOFCs is a substantial scientific challenge.Herein we investigated the use of La_(0.75)Sr_(0.25)Cr_(0.5)Mn_(0.5)O_(3)-δ−Ce_(0.8)Gd_(0.2)O_(1.9)(LSCM−GDC)composite electrodes as anodes for La_(0.9)Sr_(0.1)Ga_(0.8)Mg_(0.2)O_(3)-δelectrolyte-based DC-SOFCs,with Camellia oleifera shell char as the carbon fuel.The LSCM−GDC-anode DC-SOFC delivered a maximum power density of 221 mW/cm^(2) at 800℃ and it significantly improved to 425 mW/cm^(2) after Ni nanoparticles were introduced into the LSCM−GDC anode through wet impregnation.The microstructures of the prepared anodes were characterized,and the stability of the anode in a DC-SOFC and the influence of catalytic activity on open circuit voltage were studied.The above results indicate that LSCM–GDC anode is promising to be applied in DC-SOFCs.展开更多
In the DF1-1 Gas Field in the Yinggehai Basin, South China Sea, the velocity-depth plot and velocity spectra show significant variations from a linear trend, exhibiting a distinct reversal phenomenon. Velocity paramet...In the DF1-1 Gas Field in the Yinggehai Basin, South China Sea, the velocity-depth plot and velocity spectra show significant variations from a linear trend, exhibiting a distinct reversal phenomenon. Velocity parameters derived from velocity spectral analysis of the seismic data and sonic logs indicate that the interval velocity reverses below 2,100 m (2.2 s two-way time (TWT)) in the DF1-1 Gas Field. Some direct hydrocarbon indicators (DHIs) models developed for the shallow strata cannot be simply applied to the moderately to deeply buried strata for direct exploration target recognition because the velocity reversal has caused the middle-deep gas reservoirs to exhibit a moderate or weak seismic amplitude. The hydrocarbon indicator method of “Differential Interformational Velocity Analysis (DIVA)” with the aid of other hydrocarbon indicating techniques was employed to effectively identify DHIs in the middle-deep strata under velocity inversion. The result has shown that the DIVA technique can be effectively used as a DHI in both the shallow and the middle-deep strata in the study area with the shallow strata characterized by Type I DIVA anomaly and the middle-deep strata characterized by the Type II DIVA anomaly.展开更多
DFT/6-31G^* calculations were applied to study the direct aldol reaction between acetone and 4-nitrobenzaldehyde catalyzed by (S)-proline. Four transition states associated with the stereo-controlling step, corresp...DFT/6-31G^* calculations were applied to study the direct aldol reaction between acetone and 4-nitrobenzaldehyde catalyzed by (S)-proline. Four transition states associated with the stereo-controlling step, corresponding to syn and anti arrangements of methylene moiety related to the carboxylic acid group in enamine intermediate and re and si attacks to the aldehyde carbonyl carbon have been obtained. The solvent effect of DMSO was investigated with polarized continuum model. The computed energies of transition states reveal the stereo-selectivity of the reaction.展开更多
Conference Theme Advanced Technologies for Emergency Planning and ResponseThe 2008 IEEE International Conference on Networking, Sensing and Control will be held in Sanya,China. The main theme of the conference is adva...Conference Theme Advanced Technologies for Emergency Planning and ResponseThe 2008 IEEE International Conference on Networking, Sensing and Control will be held in Sanya,China. The main theme of the conference is advanced technologies for emergency planning and re-展开更多
The performance of multi-channel Compressive Sensing (CS)-based Direction-of-Arrival (DOA) estimation algorithm degrades when the gains between Radio Frequency (RF) channels are inconsistent, and when target angle inf...The performance of multi-channel Compressive Sensing (CS)-based Direction-of-Arrival (DOA) estimation algorithm degrades when the gains between Radio Frequency (RF) channels are inconsistent, and when target angle information mismatches with system sensing model. To solve these problems, a novel single-channel CS-based DOA estimation algorithm via sensing model optimization is proposed. Firstly, a DOA sparse sensing model using single-channel array considering the sensing model mismatch is established. Secondly, a new single-channel CS-based DOA estimation algorithm is presented. The basic idea behind the proposed algorithm is to iteratively solve two CS optimizations with respect to target angle information vector and sensing model quantization error vector, respectively. In addition, it avoids the loss of DOA estimation performance caused by the inconsistent gain between RF channels. Finally, simulation results are presented to verify the efficacy of the proposed algorithm.展开更多
基金Supported by the National Natural Science Foundation of China(61203021)the Key Science and Technology Program of Liaoning Province(2011216011)+1 种基金the Natural Science Foundation of Liaoning Province(2013020024)the Program for Liaoning Excellent Talents in Universities(LJQ2015061)
文摘Electrical capacitance tomography(ECT)has been applied to two-phase flow measurement in recent years.Image reconstruction algorithms play an important role in the successful applications of ECT.To solve the ill-posed and nonlinear inverse problem of ECT image reconstruction,a new ECT image reconstruction method based on fast linearized alternating direction method of multipliers(FLADMM)is proposed in this paper.On the basis of theoretical analysis of compressed sensing(CS),the data acquisition of ECT is regarded as a linear measurement process of permittivity distribution signal of pipe section.A new measurement matrix is designed and L1 regularization method is used to convert ECT inverse problem to a convex relaxation problem which contains prior knowledge.A new fast alternating direction method of multipliers which contained linearized idea is employed to minimize the objective function.Simulation data and experimental results indicate that compared with other methods,the quality and speed of reconstructed images are markedly improved.Also,the dynamic experimental results indicate that the proposed algorithm can ful fill the real-time requirement of ECT systems in the application.
基金This project was funded in part bythe U . S . Army
文摘A fiber Bragg grating (FBG) geophone and a surface seismic wave-based algorithm for detecting the direction of arrival (DOA) are described. The operational principle of FBG geophone is introduced and illustrated with systematic experimental data, demonstrating an improved FBG geophone with many advantages over the conventional geophones. An innovative, robust, and simple algorithm is developed for obtaining the bearing information on the seismic events, such as people walking, or vehicles moving. Such DOA estimate is based on the interactions and projections of surface-propagating seismic waves generated by the moving personnel or vehicles with a single tri-axial seismic sensor based on FBGs. Of particular interest is the case when the distance between the source of the seismic wave and the detector is less than or comparable to one wavelength (less than 100 m), corresponding to near-field detection, where an effective method of DOA finding lacks.
文摘Fiber-based curvature sensors,especially those capable of discerning the direction of curvature,have attracted more and more interest due to their promising applications in structural health monitoring,high-precision measurement,medical and biological diagnosis-treat instruments,and so on.Here,we propose and demonstrate a compact directional curvature sensor that comprises two bridged waveguides and three Bragg gratings in a section of three-core fiber(TCF).Both the waveguides and gratings are integrated by femtosecond laser micromachining method.The waveguides,connecting the TCF outer cores to the lead-in single-mode fiber core,function as beam couplers to realize simultaneous interrogation of all three gratings without any separate fan-in/out component.Owing to the spatial specificity,the outer-core gratings exhibit high and direction-dependent sensitivity to curvature,whereas the central-core grating is nearly insensitive to curvature but shows similar sensitivities to ambient temperature and axial strain as the outer-core gratings.It can be used to compensate the cross impact of temperature and strain when the outer-core gratings are applied for curvature detection.Moreover,the wavelength interval between two outer-core gratings is also proposed as an indicator for curvature sensing.It features with a much higher sensitivity to curvature and reduced sensitivities to temperature and axial strain.The corresponding maximum sensitivity to curvature is as high as 191.89 pm/m-1,while the sensitivities to temperature and strain are only 0.3 pm/℃and 0.0218 pm/με,respectively.Therefore,our proposed device provides a compact and robust all-infiber solution for directional curvature sensing.It not only offers high sensitivity and accuracy but also immunity to temperature and axial strain fluctuations,making it a promising tool for a wide range of applications.
基金supported in part by the National Natural Science Foundation of China (Grant Nos.62273314,U21A20141,and 51821003)Fundamental Research Program of Shanxi Province (Grant No.202303021224008)Shanxi Province Key Laboratory of Quantum Sensing and Precision Measure-ment (Grant No.201905D121001).
文摘It is found that when the parity–time symmetry phenomenon is introduced into the resonant optical gyro system and it works near the exceptional point,the sensitivity can in theory be significantly amplified at low angular rate.However,in fact,the exceptional point is easily disturbed by external environmental variables,which means that it depends on harsh experimental environment and strong control ability,so it is difficult to move towards practical application.Here,we propose a new angular rate sensor structure based on exceptional surface,which has the advantages of high sensitivity and high robustness.The system consists of two fiber-optic ring resonators and two optical loop mirrors,and one of the resonators contains a variable ratio coupler and a variable optical attenuator.We theoretically analyze the system response,and the effects of phase and coupling ratio on the system response.Finally,compared with the conventional resonant gyro,the sensitivity of this exceptional surface angular rate sensor can be improved by about 300 times at low speed.In addition,by changing the loss coefficient in the ring resonator,we can achieve a wide range of 600 rad/s.This scheme provides a new approach for the development of ultra-high sensitivity and wide range angular rate sensors in the future.
基金supported by the National Basic Research Program of China。
文摘With the extensive application of large-scale array antennas,the increasing number of array elements leads to the increasing dimension of received signals,making it difficult to meet the real-time requirement of direction of arrival(DOA)estimation due to the computational complexity of algorithms.Traditional subspace algorithms require estimation of the covariance matrix,which has high computational complexity and is prone to producing spurious peaks.In order to reduce the computational complexity of DOA estimation algorithms and improve their estimation accuracy under large array elements,this paper proposes a DOA estimation method based on Krylov subspace and weighted l_(1)-norm.The method uses the multistage Wiener filter(MSWF)iteration to solve the basis of the Krylov subspace as an estimate of the signal subspace,further uses the measurement matrix to reduce the dimensionality of the signal subspace observation,constructs a weighted matrix,and combines the sparse reconstruction to establish a convex optimization function based on the residual sum of squares and weighted l_(1)-norm to solve the target DOA.Simulation results show that the proposed method has high resolution under large array conditions,effectively suppresses spurious peaks,reduces computational complexity,and has good robustness for low signal to noise ratio(SNR)environment.
文摘Introduction and Invitation DICP Symposium is a special series of interna-tional conference named after the Dalian Instituteof Chemical Physics (DICP). The DICP Symposiumwas founded with the purpose to promote the interna-tional communication and collaboration between theDICP and the international scientific community, to
文摘The Liaoji Proterozoic rift is an inter-intracontinenatl rift developed from Archean granite-greenstone tectonic regime and contains many important mineral deposits of U, B, magnesite, Pb-Zn, Au, Ag, Co and P. These deposits were formed as the result of late mobilization, transportation and concentfation of the previously enriched ore-forming mate- rials in several ore-bearing formations formed during the rift stage. So the metallogeny of these deposits in the rift shows both inheritance and new generation of the ore-forming materials. In future ore-searching practice, attentions should be paid on the studies of the ore-bearing formations in the rift, on the multiple stages of metallogeny and and on multiple derivations of the ore-forming materials.
基金Project supported by the National Natural Science Foundation of China (No. 20276064) and Natural Science Foundation of ZhejiangProvince (No. Z304076), China
文摘In order to improve the thermostability of β- 1,3-1,4-glucanase, evolutionary molecular engineering was used to evolve the β-1,3-1,4-glucanase from Bacillus subtilis ZJF-1A5. The process involves random mutation by error-prone PCR and DNA shuffling followed by screening on the filter-based assay. Two mutants, EGsl and EGs2, were found to have four and five amino acid substitutions, respectively. These substitutions resulted in an increase in melting temperature from Tm=62.5℃ for the wild-type enzyme to Tm=65.5℃ for the mutant EGsl and 67.5℃ for the mutant EGs2. However, the two mutated enzymes had opposite approaches to produce reducing sugar from lichenin with either much higher (28%) for the former or much lower (21.6%) for the latter in comparison with their parental enzymes. The results demonstrate that directed evolution is an effective approach to improve the thermostability of a mesophilic enzyme.
基金Supported by Grants for AIDS Research from the Ministry of HealthLabor and Welfare of Japan (Shima M),Special Coordination Funds for Promoting Science and Technology (Ohashi K and Okano T)+1 种基金Grant-in-Aid (Ohashi K,No.21300180) from the Ministry of Education,Culture,Sports and Science and Technology (MEXT) of Japan (Ohashi K and Okano T)Novartis Foundation Japan (Ohashi K),and Bayer Hemophilia Award Program (Ohashi K)
文摘AIM: To investigate the molecular mechanisms involved in coagulation factor expression and/or function during direct hyperplasia (DH)-mediated liver regeneration. METHODS: Direct hyperplasia-mediated liver regeneration was induced in female C57BL/6 mice by administering 1,4-bisr2-(3,5-dichloropyridyloxy)] benzene (TCPOBOP), a representative hepatomitogen. Mice were weighed and sacrificed at various time points [Day 0 (D0: prior to injection), 3 h, D1, D2, D3, and D10] after TCPOBOP administration to obtain liver and blood samples. Using the RNA samples extracted from the liver, a comprehensive analysis was performed on the hepatic gene expression profiling of coagulation-related factors by real-time RT-PCR (fibrinogen, prothrombin, factors Ⅴ, Ⅶ, Ⅷ, Ⅸ, Ⅹ, Ⅺ, Ⅻ, ⅩⅢβ , plasminogen, antithrombin, protein C, protein S, ADAMTS13, and VWF). The corresponding plasma levels of coagulation factors (fibrinogen, prothrombin, factors Ⅴ, Ⅶ, Ⅷ, Ⅸ, Ⅹ, Ⅺ, Ⅻ, ⅩⅢ, and VWF) were also analyzed and compared with their mRNA levels. RESULTS: Gavage administration of TCPOBOP (3 mg/kg body weight) resulted in a marked and gradual increase in the weight of the mouse livers relative to the total body weight to 220% by D10 relative to the DO (control) ratios. At the peak of liver regeneration (D1 and D2), the gene expression levels for most of the coagulationrelated factors (fibrinogen, prothrombin, factors Ⅴ, Ⅶ, Ⅷ, Ⅸ,Ⅺ, Ⅻ, ⅩⅢβ, plasminogen, antithrombin, protein C, ADAMTS13, VWF) were found to be downregulated in a time-dependent manner, and gradually recovered by D10 to the basal levels. Only mRNA levels of factor X and protein S failed to show any decrease during the regenerative phase. As for the plasma levels, 5 clotting factors (prothrombin, factors Ⅷ, Ⅸ, Ⅺ, and Ⅻ) demonstrated a significant decrease (P 〈 0.05) during the regeneration phase compared with DO. Among these 5 factors, factor Ⅸ and factor Ⅺ showed the most dramatic decline in their activities by about 50% at D2 compared to the basal levels, and these reductions in plasma activity for both factors were consistent with our RT-PCR findings. In contrast, the plasma activities of the other coagulation factors (fibrinogen, factors Ⅴ, Ⅶ, ⅩⅢ, and VWF) were not significantly reduced, despite the reduction in the liver mRNA levels. Unlike the other factors, FX showed a temporal increase in its plasma activity, with significant increases (P 〈 0.05) detected at DI. CONCLUSION: Investigating the coagulation cascade protein profiles during liver regeneration by DH may help to better understand the basic biology of the liver under normal and pathological conditions.
文摘针对典型感潮河网地区水环境污染日趋严重与洪涝灾害频发的问题,为优化河网水动力和降低河道漫溢风险,基于Info Works ICM(integrated catchment management)模型建立福州市仓山区龙津阳岐片区城市水文模型与一维河网水动力耦合模型,以2022年6月14日实测降雨及河道水位数据对模型参数进行校准,平均纳什效率系数为0.78,平均洪峰误差为1.5%。设计并模拟3种晴天工况和3种“卢碧”台风雨天工况,结果表明:晴天从无调控到工况3,随着引水量的增加,河网平均流速逐步增加,总体增加66.4%,河道水动力提升显著;雨天从原有调控工况到工况3,随着河道预降水位值增大,关键断面平均超警历时逐步减少,总体下降73%,河道漫溢风险明显降低。构建河网水文水动力耦合模型和工况优选,可为仓山区进一步提升河网水动力与城市汛期洪涝灾害防治能力的方案制定提供决策依据,也可为其他同类研究提供借鉴。
基金This work was financially supported by the Science Council, Taiwan (Project No. NSC 91 2611 E 019 007)
文摘Measurements of wave heights with image sequences from a Charged Coupled Device(CCD) camera were made. Sinusoidal, as well as unidirectional and directional, waves were used for the experiments. A transfer function was obtained by calibration of the magnitudes of the gray values of the images against the results of wave gauge measurements for directional waves. With this transfer function, wave heights for regular waves were deduced. It is shown that the average relative errors are smaller than 16% for both unidirectional and directional waves.
文摘This paper proposes an adaptive sparsity-based direct position determination (DPD) appoach to locate multiple targets in the case of time-varying channels. The novel feature of this method is to dynamically adjust both the overcomplete basis and the sparse solution based on a two-step dictionary learning (DL) framework. The method first performs supervised offline DL by using the quadratic programming approach, and then the dictionary is continuously updated in an incremental fashion to adapt to the time-varying channel during the online stage. Furthermore, the method does not need the number of emitters a prior. Simulation results demonstrate the performance of the proposed algorithm on the location estimation accuracy.
基金Project(2019YFC1907405)supported by the National Key R&D Program of ChinaProject(GJJ200809)supported by the Education Department Project Fund of Jiangxi Province,ChinaProject(2020BAB214021)supported by the Natural Science Foundation of Jiangxi Province,China。
文摘Direct carbon solid oxide fuel cells(DC-SOFCs)are promising,green,and efficient power-generating devices that are fueled by solid carbons and comprise all-solid-state structures.Developing suitable anode materials for DC-SOFCs is a substantial scientific challenge.Herein we investigated the use of La_(0.75)Sr_(0.25)Cr_(0.5)Mn_(0.5)O_(3)-δ−Ce_(0.8)Gd_(0.2)O_(1.9)(LSCM−GDC)composite electrodes as anodes for La_(0.9)Sr_(0.1)Ga_(0.8)Mg_(0.2)O_(3)-δelectrolyte-based DC-SOFCs,with Camellia oleifera shell char as the carbon fuel.The LSCM−GDC-anode DC-SOFC delivered a maximum power density of 221 mW/cm^(2) at 800℃ and it significantly improved to 425 mW/cm^(2) after Ni nanoparticles were introduced into the LSCM−GDC anode through wet impregnation.The microstructures of the prepared anodes were characterized,and the stability of the anode in a DC-SOFC and the influence of catalytic activity on open circuit voltage were studied.The above results indicate that LSCM–GDC anode is promising to be applied in DC-SOFCs.
基金supported by the National Natural Science Foundation of China (No.40702024)the Project was sponsored by the Scientific Research Foundation for the Returned Overseas Chinese Scholars,Ministry of Education of China (No.2009022014)Open Research Foundation of Key Laboratory of Tectonics and Petroleum Resources (China University of Geosciences),Ministry of Education (No.TPR-2009-33)
文摘In the DF1-1 Gas Field in the Yinggehai Basin, South China Sea, the velocity-depth plot and velocity spectra show significant variations from a linear trend, exhibiting a distinct reversal phenomenon. Velocity parameters derived from velocity spectral analysis of the seismic data and sonic logs indicate that the interval velocity reverses below 2,100 m (2.2 s two-way time (TWT)) in the DF1-1 Gas Field. Some direct hydrocarbon indicators (DHIs) models developed for the shallow strata cannot be simply applied to the moderately to deeply buried strata for direct exploration target recognition because the velocity reversal has caused the middle-deep gas reservoirs to exhibit a moderate or weak seismic amplitude. The hydrocarbon indicator method of “Differential Interformational Velocity Analysis (DIVA)” with the aid of other hydrocarbon indicating techniques was employed to effectively identify DHIs in the middle-deep strata under velocity inversion. The result has shown that the DIVA technique can be effectively used as a DHI in both the shallow and the middle-deep strata in the study area with the shallow strata characterized by Type I DIVA anomaly and the middle-deep strata characterized by the Type II DIVA anomaly.
基金This project was supported by the Research Foundation of Key Laboratory of Organic Synthesis of Jiangsu Province (No. JSK010)
文摘DFT/6-31G^* calculations were applied to study the direct aldol reaction between acetone and 4-nitrobenzaldehyde catalyzed by (S)-proline. Four transition states associated with the stereo-controlling step, corresponding to syn and anti arrangements of methylene moiety related to the carboxylic acid group in enamine intermediate and re and si attacks to the aldehyde carbonyl carbon have been obtained. The solvent effect of DMSO was investigated with polarized continuum model. The computed energies of transition states reveal the stereo-selectivity of the reaction.
文摘Conference Theme Advanced Technologies for Emergency Planning and ResponseThe 2008 IEEE International Conference on Networking, Sensing and Control will be held in Sanya,China. The main theme of the conference is advanced technologies for emergency planning and re-
文摘The performance of multi-channel Compressive Sensing (CS)-based Direction-of-Arrival (DOA) estimation algorithm degrades when the gains between Radio Frequency (RF) channels are inconsistent, and when target angle information mismatches with system sensing model. To solve these problems, a novel single-channel CS-based DOA estimation algorithm via sensing model optimization is proposed. Firstly, a DOA sparse sensing model using single-channel array considering the sensing model mismatch is established. Secondly, a new single-channel CS-based DOA estimation algorithm is presented. The basic idea behind the proposed algorithm is to iteratively solve two CS optimizations with respect to target angle information vector and sensing model quantization error vector, respectively. In addition, it avoids the loss of DOA estimation performance caused by the inconsistent gain between RF channels. Finally, simulation results are presented to verify the efficacy of the proposed algorithm.