Effects of Ultrafine Comminution on the Dissolution of Active Ingredients from Compound Feed Additive of Strobilanthes cusia

[Objective] The research aimed to explore the effects of comminution technology on the dissolution of active components from compound feed additive of Strobi/anthes cusia. [Method] Using active component adenosine in principal herb S. cusia and chlorogenic acid in minister drug Lonicera japonica Thunb. as dissolution indices,the effects of ultrafine comminution on the dissolution degree of compound feed additive of S. cusia were analyzed. [ Result] The dissolution degree of adenosine and chlorogenic acid in ultra micro particles were obviously higher than that of common particles. Ultrafine comminution could significantly quicken the dissolution rate of adenosine and chlorogenic acid in compound feed additive of S. cusia, shorten the extraction time, avoid the breakage of active components in long-time extraction process,and meanwhile saved the energy greatly. [ Conclusion] The ultrafine comminution technology could obviously increase the dissolution degree of active components in compound feed additive of S. cusia.