As the core component of energy conversion for large wind turbines,the output performance of doubly-fed induction generators (DFIGs) plays a decisive role in the power quality of wind turbines.To realize the fast and ...As the core component of energy conversion for large wind turbines,the output performance of doubly-fed induction generators (DFIGs) plays a decisive role in the power quality of wind turbines.To realize the fast and accurate design optimization of DFIGs,this paper proposes a novel hybriddriven surrogate-assisted optimization method.It firstly establishes an accurate subdomain model of DFIGs to analytically predict performance indexes.Furthermore,taking the inexpensive analytical dataset produced by the subdomain model as the source domain and the expensive finite element analysis dataset as the target domain,a high-precision surrogate model is trained in a transfer learning way and used for the subsequent multi-objective optimization process.Based on this model,taking the total harmonic distortion of electromotive force,cogging torque,and iron loss as objectives,and the slot and inner/outer diameters as parameters for optimizing the topology,achieve a rapid and accurate electromagnetic design for DFIGs.Finally,experiments are carried out on a 3MW DFIG to validate the effectiveness of the proposed method.展开更多
Because the mover and stator of a doubly-fed linear motor are both equipped with three-phase windings, the motor enables contactless energy to be transferred from the stator to the mover. Thus, when a doubly-fed linea...Because the mover and stator of a doubly-fed linear motor are both equipped with three-phase windings, the motor enables contactless energy to be transferred from the stator to the mover. Thus, when a doubly-fed linear motor is used in the linear driving system of trains, neither an overhead line nor a third rail is needed. However, the doubly- fed motor will lead to more severe thrust fluctuation than the unilateral motors. In order to overcome this shortcoming, the thrust fluctuation of the doubly-fed motor should be analyzed. In this paper, an expression for motor thrust is derived. It points out that the slot effect caused by the slotted structure is the main reason for the increase of thrust fluctuation. The method of adopting unequal pole pitch and unequal slot numbers per pole per phase of stator and mover, is proposed to weaken the slot effect when designing the motor slot parameters. Three different motor models are simulated by ANSOFT. The proposed method results in a motor thrust fluctuation coefficient of 8.4%, compared to 49.4% for the conventional method. Therefore, the motor's thrust fluctuation is effectively suppressed by the proposed method.展开更多
Spinal cord injury necessitates effective rehabilitation strategies, with exercise therapies showing promise in promoting recovery. This study investigated the impact of rehabilitation exercise on functional recovery ...Spinal cord injury necessitates effective rehabilitation strategies, with exercise therapies showing promise in promoting recovery. This study investigated the impact of rehabilitation exercise on functional recovery and morphological changes following thoracic contusive spinal cord injury. After a 7-day recovery period after spinal cord injury, mice were assigned to either a trained group(10 weeks of voluntary running wheel or forced treadmill exercise) or an untrained group. Bi-weekly assessments revealed that the exercise-trained group, particularly the voluntary wheel exercise subgroup, displayed significantly improved locomotor recovery, more plasticity of dopaminergic and serotonin modulation compared with the untrained group. Additionally, exercise interventions led to gait pattern restoration and enhanced transcranial magnetic motor-evoked potentials. Despite consistent injury areas across groups, exercise training promoted terminal innervation of descending axons. In summary, voluntary wheel exercise shows promise for enhancing outcomes after thoracic contusive spinal cord injury, emphasizing the role of exercise modality in promoting recovery and morphological changes in spinal cord injuries. Our findings will influence future strategies for rehabilitation exercises, restoring functional movement after spinal cord injury.展开更多
Amyotrophic lateral sclerosis is a rare neurodegenerative disease characterized by the involvement of both upper and lower motor neurons.Early bilateral limb involvement significantly affects patients'daily lives ...Amyotrophic lateral sclerosis is a rare neurodegenerative disease characterized by the involvement of both upper and lower motor neurons.Early bilateral limb involvement significantly affects patients'daily lives and may lead them to be confined to bed.However,the effect of upper and lower motor neuron impairment and other risk factors on bilateral limb involvement is unclear.To address this issue,we retrospectively collected data from 586 amyotrophic lateral sclerosis patients with limb onset diagnosed at Peking University Third Hospital between January 2020 and May 2022.A univariate analysis revealed no significant differences in the time intervals of spread in different directions between individuals with upper motor neuron-dominant amyotrophic lateral sclerosis and those with classic amyotrophic lateral sclerosis.We used causal directed acyclic graphs for risk factor determination and Cox proportional hazards models to investigate the association between the duration of bilateral limb involvement and clinical baseline characteristics in amyotrophic lateral sclerosis patients.Multiple factor analyses revealed that higher upper motor neuron scores(hazard ratio[HR]=1.05,95%confidence interval[CI]=1.01–1.09,P=0.018),onset in the left limb(HR=0.72,95%CI=0.58–0.89,P=0.002),and a horizontal pattern of progression(HR=0.46,95%CI=0.37–0.58,P<0.001)were risk factors for a shorter interval until bilateral limb involvement.The results demonstrated that a greater degree of upper motor neuron involvement might cause contralateral limb involvement to progress more quickly in limb-onset amyotrophic lateral sclerosis patients.These findings may improve the management of amyotrophic lateral sclerosis patients with limb onset and the prediction of patient prognosis.展开更多
The brushless doubly-fed wind power system based on conventional power control strategies lacks ‘inertia’ and the ability to support grid,which leads to the decline of grid stability.Therefore,a control strategy of ...The brushless doubly-fed wind power system based on conventional power control strategies lacks ‘inertia’ and the ability to support grid,which leads to the decline of grid stability.Therefore,a control strategy of brushless doubly-fed reluctance generator(BDFRG) based on virtual synchronous generator(VSG) control is proposed to solve the problem in this paper.The output characteristics of BDFRG based on VSG are similar to a synchronous generator(SG),which can support the grid frequency and increase the system ‘inertia’.According to the mathematical model of BDFRG,the inner loop voltage source control of BDFRG is derived.In addition,the specific structure and parameter selection principle of outer loop VSG control are expounded.The voltage source control inner loop of BDFRG is combined with the VSG control outer loop to establish the overall architecture of BDFRG-VSG control strategy.Finally,the effectiveness and feasibility of the proposed strategy are verified in the simulation.展开更多
Owing to their stability,doubly-fed induction generator(DFIG)integrated systems have gained considerable interest and are the most widely implemented type of wind turbines and due to the increasing escalation of the w...Owing to their stability,doubly-fed induction generator(DFIG)integrated systems have gained considerable interest and are the most widely implemented type of wind turbines and due to the increasing escalation of the wind generation penetration rate in power systems.In this study,we investigate a DFIG integrated system comprising four modules:(1)a wind turbine that considers the maximum power point tracking and pitch-angle control,(2)induction generator,(3)rotor/grid-side converter with the corresponding control strategy,and(4)AC power grid.The detailed small-signal modeling of the entire system is performed by linearizing the dynamic characteristic equation at the steady-state value.Furthermore,a dichotomy method is proposed based on the maximum eigenvalue real part function to obtain the critical value of the parameters.Root-locus analysis is employed to analyze the impact of changes in the phase-locked loop,short-circuit ratio,and blade inertia on the system stability.Lastly,the accuracy of the small-signal model and the real and imaginary parts of the calculated dominant poles in the theoretical analysis are verified using PSCAD/EMTDC.展开更多
To lower the difficulty of fault protection,a doubly-fed induction machine based shipboard propulsion system(DFIM-SPS)that is partially power decoupled is presented.In such an intrinsically safe SPS architecture,a syn...To lower the difficulty of fault protection,a doubly-fed induction machine based shipboard propulsion system(DFIM-SPS)that is partially power decoupled is presented.In such an intrinsically safe SPS architecture,a synchronous generator(SG)is employed for power generation,and the accuracy of the parameters of power generation unit(PGU)plays an important role in SPS stable operation.In this paper,the PGU parameter deviations are studied to evaluate the effects on system performance.The models of salient-pole SG,type DC1A excitation system(EXS)and DFIM are illustrated first.Besides,the corresponding control scheme is explained.For the 16 important parameters of PGU,up to 40%of parameter deviations are applied to implement parameter sensitivity analysis.Then,simulation studies are carried out to evaluate the parameter deviation effects on system performance in detail.By defining three parameter deviation effect indicators(PDEIs),the effects on the PGU output variables,which are the terminal voltage and output active power,are studied.Moreover,the increasing rates of PDEIs with different degrees of parameter deviations for the key parameters are analyzed.Furthermore,the overall system performance is investigated for the two most influential PGU parameters.This paper provides some vital clues on SG and EXS parameter identification for DFIM-SPS.展开更多
The aim of this paper is to investigate an adaptive sensorless direct voltage control(DVC)strategy for the stand-alone ship shaft brushless doubly-fed induction generators(BDFIGs).The proposed new rotor position obser...The aim of this paper is to investigate an adaptive sensorless direct voltage control(DVC)strategy for the stand-alone ship shaft brushless doubly-fed induction generators(BDFIGs).The proposed new rotor position observer using the space vector flux relations of BDFIG may achieve the desired voltage control of the power winding(PW)in terms of magnitude and frequency,without any speed/position sensors.The proposed algorithm does not require any additional observers for obtaining the generator speed.The proposed technique can directly achieve the desired DVC based on the estimated rotor position,which may reduce the overall system cost.The stability analysis of the proposed observer is investigated and confirmed with the concept of quadratic Lyapunov function and using the multi-model representation.In addition,the sensitivity analysis of the presented method is confirmed under different issues of parameter uncertainties.Comprehensive results from both simulation and experiments are realized with a prototype wound-rotor BDFIG,which demonstrate the capability and efficacy of the proposed sensorless DVC strategy with good transient behavior under different operating conditions.Furthermore,the analysis confirms the robustness of the proposed observer via the machine parameter changes.展开更多
A novel transient rotor current control scheme is proposed in this paper for a doubly-fed induction generator(DFIG)equipped with a superconducting magnetic energy storage(SMES) device to enhance its transient volt...A novel transient rotor current control scheme is proposed in this paper for a doubly-fed induction generator(DFIG)equipped with a superconducting magnetic energy storage(SMES) device to enhance its transient voltage and frequency support capacity during grid faults. The SMES connected to the DC-link capacitor of the DFIG is controlled to regulate the transient dc-link voltage so that the whole capacity of the grid side converter(GSC) is dedicated to injecting reactive power to the grid for the transient voltage support. However, the rotor-side converter(RSC) has different control tasks for different periods of the grid fault. Firstly, for Period I, the RSC injects the demagnetizing current to ensure the controllability of the rotor voltage. Then, since the dc stator flux degenerates rapidly in Period II, the required demagnetizing current is low in Period II and the RSC uses the spare capacity to additionally generate the reactive(priority) and active current so that the transient voltage capability is corroborated and the DFIG also positively responds to the system frequency dynamic at the earliest time. Finally, a small amount of demagnetizing current is provided after the fault clearance. Most of the RSC capacity is used to inject the active current to further support the frequency recovery of the system. Simulations are carried out on a simple power system with a wind farm. Comparisons with other commonly used control methods are performed to validate the proposed control method.展开更多
The performance characteristics,particularly the starting performance of direct line-fed induction motors,which are mainly influenced by the design of the rotor,are crucial considerations for end-users.It is quite a c...The performance characteristics,particularly the starting performance of direct line-fed induction motors,which are mainly influenced by the design of the rotor,are crucial considerations for end-users.It is quite a challenging issue for motor manufacturers to enhance the starting performance of existing mass-produced motors with minimal modifications and expenses.In this paper,a simple and cost-effective method to improve the starting performance of a commercial squirrel-cage induction motor(SCIM)is proposed.The influence of geometric parameters of the end-ring on the performance characteristics,including starting(locked rotor)torque,pull-up and break down torque,starting current,rotor electric parameters,current density,power losses,and efficiency have been comprehensively investigated.It has been revealed that among the other end-ring design parameters,the ring thickness has a significant effect on the performance characteristics.An optimal end-ring thickness is determined,and its performance characteristics have been compared to those of its initial counterpart.Numeric and parametric analyses have been conducted using a 2D time-stepping finite element method(FEM).The FEM results were validated using experimental measurements obtained from an 11 kW SCIM prototype.展开更多
Multiple sclerosis is a chronic autoimmune disease of the central nervous system and is generally considered to be a non-traumatic,physically debilitating neurological disorder.In addition to experiencing motor disabi...Multiple sclerosis is a chronic autoimmune disease of the central nervous system and is generally considered to be a non-traumatic,physically debilitating neurological disorder.In addition to experiencing motor disability,patients with multiple sclerosis also experience a variety of nonmotor symptoms,including cognitive deficits,anxiety,depression,sensory impairments,and pain.However,the pathogenesis and treatment of such non-motor symptoms in multiple scle rosis are still under research.Preclinical studies for multiple sclerosis benefit from the use of disease-appropriate animal models,including experimental autoimmune encephalomyelitis.Prior to understanding the pathophysiology and developing treatments for non-motor symptoms,it is critical to chara cterize the animal model in terms of its ability to replicate certain non-motor features of multiple sclerosis.As such,no single animal model can mimic the entire spectrum of symptoms.This review focuses on the non-motor symptoms that have been investigated in animal models of multiple sclerosis as well as possible underlying mechanisms.Further,we highlighted gaps in the literature to explain the nonmotor aspects of multiple sclerosis in expe rimental animal models,which will serve as the basis for future studies.展开更多
The harmonics that appear in the squirrel cage asynchronous machine have been discussed in great detail in the literature for a long time. However, the systematization of the phenomenon is still pending, so we made an...The harmonics that appear in the squirrel cage asynchronous machine have been discussed in great detail in the literature for a long time. However, the systematization of the phenomenon is still pending, so we made an attempt to fill this gap in the previous parts of our study by elaborating formulas for calculation of parasitic torques. It was a general demand among those who work in this field towards the author to verify his formulas with measurements. In the literature, it seems,only one detailed, purposeful series of measurements has been published so far, the purpose of which was to investigate the effect of the number of rotor slots on the torque-speed characteristic curve of the machine. The main goal of this study is to verify the correctness of the formulas by comparing them with the referred series of measurements. Relying on this, the expected synchronous parasitic torques were developed for the frequently used rotor slot numbers-as a design guide for the engineer.Thus, together with our complete table for radial magnetic pull published in our previous work, the designer has all the principles, data and formulas available for the right number of rotor slots for his given machine and for the drive system. This brings this series of papers to an end.展开更多
In order to solve the problems of rotor overvoltage,overcurrent and DC side voltage rise caused by grid voltage drops,a coordinated control strategy based on symmetrical and asymmetrical low voltage ride through of ro...In order to solve the problems of rotor overvoltage,overcurrent and DC side voltage rise caused by grid voltage drops,a coordinated control strategy based on symmetrical and asymmetrical low voltage ride through of rotor side converter of the doubly-fed generator is proposed.When the power grid voltage drops symmetrically,the generator approximate equation under steady-state conditions is no longer applicable.Considering the dynamic process of stator current excitation,according to the change of stator flux and the depth of voltage drop,the system can dynamically provide reactive power support for parallel nodes and suppress the rise of DC side voltage and rotor over-current.When the grid voltage drops asymmetrically,the positive and negative sequence components are separated in the rotating coordinate system.The doubly fed generator model is established to suppress the rotor positive sequence current and negative sequence current respectively.At the same time,the output voltage limit of the converter is discussed,and the reference value is adjusted within the allowable output voltage range.In order to adapt to the occurrence of different types of power grid faults and complex operating conditions,a fast switching module of fault type detection and rotor control mode is designed to detect the type of power grid faults and voltage drop depth in real time and switch the rotor side control mode dynamically.Finally,the simulation model of the doubly fed wind turbine is constructed in Matlab/Simulink.The simulation results verify that the proposed control strategy can improve the low-voltage ride through performance of the system when dealing with the symmetrical and asymmetric voltage drop of the power grid and identify the power grid fault type and provide the correct control strategy.展开更多
Permanent magnet synchronous motor(PMSM)speed control systems with conventional linear active disturbance rejection control(CLADRC)strategy encounter issues regarding the coupling between dynamic response and disturba...Permanent magnet synchronous motor(PMSM)speed control systems with conventional linear active disturbance rejection control(CLADRC)strategy encounter issues regarding the coupling between dynamic response and disturbance suppression and have poor performance in suppressing complex nonlinear disturbances.In order to address these issues,this paper proposes an improved two-degree-of-freedom LADRC(TDOF-LADRC)strategy,which can enhance the disturbance rejection performance of the system while decoupling entirely the system's dynamic and anti-disturbance performance to boost the system robustness and simplify controller parameter tuning.PMSM models that consider total disturbances are developed to design the TDOF-LADRC speed controller accurately.Moreover,to evaluate the control performance of the TDOF-LADRC strategy,its stability is proven,and the influence of each controller parameter on the system control performance is analyzed.Based on it,a comparison is made between the disturbance observation ability and anti-disturbance performance of TDOF-LADRC and CLADRC to prove the superiority of TDOF-LADRC in rejecting disturbances.Finally,experiments are performed on a 750 W PMSM experimental platform,and the results demonstrate that the proposed TDOF-LADRC exhibits the properties of two degrees of freedom and improves the disturbance rejection performance of the PMSM system.展开更多
Nested-loop secondary linear doubly-fed machine(NLS-LDFM) is a novel linear machine evolved from rotary brushless doubly-fed induction machine, which has a good application prospect in linear metro. In order to analyz...Nested-loop secondary linear doubly-fed machine(NLS-LDFM) is a novel linear machine evolved from rotary brushless doubly-fed induction machine, which has a good application prospect in linear metro. In order to analyze the performance of NLS-LDFM, the mechanism and action rules of end effects are investigated in this paper. Firstly, the mechanism of static and dynamic end effects is analyzed in aspect of direct coupling, winding asymmetry and transient secondary current. Furthermore, based on the winding theory for short primary linear machines, the machine parameters are established qualitatively considering pulsating magnetic field of NLS-LDFM. Finally, the NLS-LDFM performance analysis is supplemented by the finite element algorithm(FEA) simulation and experiments under different operating conditions.展开更多
Kinesin-1 motor protein is a homodimer containing two identical motor domains connected by a common long coiledcoil stalk via two flexible neck linkers. The motor can step on a microtubule with a velocity of about 1 ...Kinesin-1 motor protein is a homodimer containing two identical motor domains connected by a common long coiledcoil stalk via two flexible neck linkers. The motor can step on a microtubule with a velocity of about 1 μm·s-1and an attachment duration of about 1 s under physiological conditions. The available experimental data indicate a tradeoff between velocity and attachment duration under various experimental conditions, such as variation of the solution temperature,variation of the strain between the two motor domains, and so on. However, the underlying mechanism of the tradeoff is unknown. Here, the mechanism is explained by a theoretical study of the dynamics of the motor under various experimental conditions, reproducing quantitatively the available experimental data and providing additional predictions. How the various experimental conditions lead to different decreasing rates of attachment duration versus velocity is also explained.展开更多
Objective: In the manuscript titled “Liquid subcutaneous Levodopa-Carbidopa ND0612 effects on motor symptoms in individuals with Parkinson’s Disease: A systematic review and meta-analysis”, the objective was to con...Objective: In the manuscript titled “Liquid subcutaneous Levodopa-Carbidopa ND0612 effects on motor symptoms in individuals with Parkinson’s Disease: A systematic review and meta-analysis”, the objective was to conduct a systematic review with meta-analysis to investigate the effects ND0612 24-hour dosing regimen has on motor symptoms in individuals with Parkinson’s Disease (PD). Introduction: ND0612 is a novel minimally invasive continuous subcutaneous delivery system of liquid Levodopa-Carbidopa being investigated for the treatment of PD in individuals experiencing motor symptoms. Methods: A systematic literature search was conducted in PubMed, Cochrane, and EBSCO databases to identify randomized controlled trials investigating the effects of ND0612 on motor symptoms in individuals with PD. Outcomes included the Unified Parkinson’s Disease Rating Scale (UPDRS) Part II and Part III scores. Methodological quality was assessed using the Cochrane Grading of Recommendations Assessment, Development, and Evaluation approach. Meta-analysis was performed using a random effects model with the DerSimonian and Laird method to estimate the effects of the ND0612 24-hour dosing regimen on UPDRS Part II and Part III scores. Results: Three studies were included in our review. There were statistically significant reductions in UPDRS Part II scores (mean difference (MD) −3.299;95% confidence interval (CI) −3.438, −3.159) and in UPDRS Part III scores (MD −12.695;95% CI −24.428, −0.962) in the ND0612 24-hour dosing regimen. Results were based on very low certainty of evidence. Conclusion: Based on very low certainty evidence, the ND0612 24-hour dosing regimen is effective at improving motor symptoms in individuals with PD. Our findings suggest that ND0612 is more effective at improving UPDRS Part II and Part III scores in individuals with PD than other pharmacological and non-pharmacological treatments, warranting further study.展开更多
VFT (variable frequency transformer) has been recently used as art alternative to HVDC (high voltage direct current) to control power flow between asynchronous networks. VFT consumes less reactive power than a bac...VFT (variable frequency transformer) has been recently used as art alternative to HVDC (high voltage direct current) to control power flow between asynchronous networks. VFT consumes less reactive power than a back-to-back HVDC system, provides faster initial transient recovery, and has better natural damping capability. VFT is simply a DFIM (doubly-fed induction machine) where the machine torque controls the power flow from stator to rotor and vice versa. The main disadvantage of this VFT is the slip rings and brushes required for the rotor circuit, especially in bulk power transmission. The BDFM (brushless doubly-fed machine) with nested cage rotor machine is proved to be a comparable alternative to conventional DFIM in many applications with the advantage that all windings being in the stator frame with fixed output terminals. In this paper, the BDFM is used as a BVFT (brushless variable frequency transformer). A prototype machine is designed and simulated to verify the system validity.展开更多
Application of a DFIG (doubly-fed induction generator), which is one of adjustable speed generators, to a gas engine cogeneration system has been investigated. To operate during a blackout as an emergency power supp...Application of a DFIG (doubly-fed induction generator), which is one of adjustable speed generators, to a gas engine cogeneration system has been investigated. To operate during a blackout as an emergency power supply is one of important roles for the gas engine eogeneration system. In the case of conventional constant speed of synchronous generator, the amount of the allowed step load is limited to around 30% of the rated power. On the other hand, DFIG is expected to increase the amount of step load during the stand-alone operation. In this paper, it has been demonstrated that an increase in the gas engine speed resulted in an increase in the maximum amount of step load using experimental equipment with a real gas engine. It has been concluded that the proposed system can improve the performance of an emergency power supply at step-loading.展开更多
Background:Excessive heat exposure can lead to hyperthermia in humans,which impairs physical performance and disrupts cognitive function.While heat is a known physiological stressor,it is unclear how severe heat stres...Background:Excessive heat exposure can lead to hyperthermia in humans,which impairs physical performance and disrupts cognitive function.While heat is a known physiological stressor,it is unclear how severe heat stress affects brain physiology and function.Methods:Eleven healthy participants were subjected to heat stress from prolonged exercise or warm water immersion until their rectal temperatures(T_(re))attained 39.5℃,inducing exertional or passive hyperthermia,respectively.In a separate trial,blended ice was ingested before and during exercise as a cooling strategy.Data were compared to a control condition with seated rest(normothermic).Brain temperature(T_(br)),cerebral perfusion,and task-based brain activity were assessed using magnetic resonance imaging techniques.Results:T_(br)in motor cortex was found to be tightly regulated at rest(37.3℃±0.4℃(mean±SD))despite fluctuations in T_(re).With the development of hyperthermia,T_(br)increases and dovetails with the rising T_(re).Bilateral motor cortical activity was suppressed during high-intensity plantarflexion tasks,implying a reduced central motor drive in hyperthermic participants(T_(re)=38.5℃±0.1℃).Global gray matter perfusion and regional perfusion in sensorimotor cortex were reduced with passive hyperthermia.Executive function was poorer under a passive hyperthermic state,and this could relate to compromised visual processing as indicated by the reduced activation of left lateral-occipital cortex.Conversely,ingestion of blended ice before and during exercise alleviated the rise in both T_(re)and T_(bc)and mitigated heat-related neural perturbations.Conclusion:Severe heat exposure elevates T_(br),disrupts motor cortical activity and executive function,and this can lead to impairment of physical and cognitive performance.展开更多
文摘As the core component of energy conversion for large wind turbines,the output performance of doubly-fed induction generators (DFIGs) plays a decisive role in the power quality of wind turbines.To realize the fast and accurate design optimization of DFIGs,this paper proposes a novel hybriddriven surrogate-assisted optimization method.It firstly establishes an accurate subdomain model of DFIGs to analytically predict performance indexes.Furthermore,taking the inexpensive analytical dataset produced by the subdomain model as the source domain and the expensive finite element analysis dataset as the target domain,a high-precision surrogate model is trained in a transfer learning way and used for the subsequent multi-objective optimization process.Based on this model,taking the total harmonic distortion of electromotive force,cogging torque,and iron loss as objectives,and the slot and inner/outer diameters as parameters for optimizing the topology,achieve a rapid and accurate electromagnetic design for DFIGs.Finally,experiments are carried out on a 3MW DFIG to validate the effectiveness of the proposed method.
文摘Because the mover and stator of a doubly-fed linear motor are both equipped with three-phase windings, the motor enables contactless energy to be transferred from the stator to the mover. Thus, when a doubly-fed linear motor is used in the linear driving system of trains, neither an overhead line nor a third rail is needed. However, the doubly- fed motor will lead to more severe thrust fluctuation than the unilateral motors. In order to overcome this shortcoming, the thrust fluctuation of the doubly-fed motor should be analyzed. In this paper, an expression for motor thrust is derived. It points out that the slot effect caused by the slotted structure is the main reason for the increase of thrust fluctuation. The method of adopting unequal pole pitch and unequal slot numbers per pole per phase of stator and mover, is proposed to weaken the slot effect when designing the motor slot parameters. Three different motor models are simulated by ANSOFT. The proposed method results in a motor thrust fluctuation coefficient of 8.4%, compared to 49.4% for the conventional method. Therefore, the motor's thrust fluctuation is effectively suppressed by the proposed method.
基金supported by the NIH (R01NS103481, R01NS111776, and R01NS131489)Indiana Department of Health (ISDH58180)(all to WW)。
文摘Spinal cord injury necessitates effective rehabilitation strategies, with exercise therapies showing promise in promoting recovery. This study investigated the impact of rehabilitation exercise on functional recovery and morphological changes following thoracic contusive spinal cord injury. After a 7-day recovery period after spinal cord injury, mice were assigned to either a trained group(10 weeks of voluntary running wheel or forced treadmill exercise) or an untrained group. Bi-weekly assessments revealed that the exercise-trained group, particularly the voluntary wheel exercise subgroup, displayed significantly improved locomotor recovery, more plasticity of dopaminergic and serotonin modulation compared with the untrained group. Additionally, exercise interventions led to gait pattern restoration and enhanced transcranial magnetic motor-evoked potentials. Despite consistent injury areas across groups, exercise training promoted terminal innervation of descending axons. In summary, voluntary wheel exercise shows promise for enhancing outcomes after thoracic contusive spinal cord injury, emphasizing the role of exercise modality in promoting recovery and morphological changes in spinal cord injuries. Our findings will influence future strategies for rehabilitation exercises, restoring functional movement after spinal cord injury.
基金supported by the National Natural Science Foundation of China,Nos.82071426,81873784Clinical Cohort Construction Program of Peking University Third Hospital,No.BYSYDL2019002(all to DF)。
文摘Amyotrophic lateral sclerosis is a rare neurodegenerative disease characterized by the involvement of both upper and lower motor neurons.Early bilateral limb involvement significantly affects patients'daily lives and may lead them to be confined to bed.However,the effect of upper and lower motor neuron impairment and other risk factors on bilateral limb involvement is unclear.To address this issue,we retrospectively collected data from 586 amyotrophic lateral sclerosis patients with limb onset diagnosed at Peking University Third Hospital between January 2020 and May 2022.A univariate analysis revealed no significant differences in the time intervals of spread in different directions between individuals with upper motor neuron-dominant amyotrophic lateral sclerosis and those with classic amyotrophic lateral sclerosis.We used causal directed acyclic graphs for risk factor determination and Cox proportional hazards models to investigate the association between the duration of bilateral limb involvement and clinical baseline characteristics in amyotrophic lateral sclerosis patients.Multiple factor analyses revealed that higher upper motor neuron scores(hazard ratio[HR]=1.05,95%confidence interval[CI]=1.01–1.09,P=0.018),onset in the left limb(HR=0.72,95%CI=0.58–0.89,P=0.002),and a horizontal pattern of progression(HR=0.46,95%CI=0.37–0.58,P<0.001)were risk factors for a shorter interval until bilateral limb involvement.The results demonstrated that a greater degree of upper motor neuron involvement might cause contralateral limb involvement to progress more quickly in limb-onset amyotrophic lateral sclerosis patients.These findings may improve the management of amyotrophic lateral sclerosis patients with limb onset and the prediction of patient prognosis.
基金supported in part by the National Natural Science Foundation of China under Grant 51537007。
文摘The brushless doubly-fed wind power system based on conventional power control strategies lacks ‘inertia’ and the ability to support grid,which leads to the decline of grid stability.Therefore,a control strategy of brushless doubly-fed reluctance generator(BDFRG) based on virtual synchronous generator(VSG) control is proposed to solve the problem in this paper.The output characteristics of BDFRG based on VSG are similar to a synchronous generator(SG),which can support the grid frequency and increase the system ‘inertia’.According to the mathematical model of BDFRG,the inner loop voltage source control of BDFRG is derived.In addition,the specific structure and parameter selection principle of outer loop VSG control are expounded.The voltage source control inner loop of BDFRG is combined with the VSG control outer loop to establish the overall architecture of BDFRG-VSG control strategy.Finally,the effectiveness and feasibility of the proposed strategy are verified in the simulation.
基金supported by the Key Laboratory of Modern Power System Simulation and Control&Renewable Energy Technology,Ministry of Education(Northeast Electric Power University),Jilin 132012,China(MPSS2023-06).
文摘Owing to their stability,doubly-fed induction generator(DFIG)integrated systems have gained considerable interest and are the most widely implemented type of wind turbines and due to the increasing escalation of the wind generation penetration rate in power systems.In this study,we investigate a DFIG integrated system comprising four modules:(1)a wind turbine that considers the maximum power point tracking and pitch-angle control,(2)induction generator,(3)rotor/grid-side converter with the corresponding control strategy,and(4)AC power grid.The detailed small-signal modeling of the entire system is performed by linearizing the dynamic characteristic equation at the steady-state value.Furthermore,a dichotomy method is proposed based on the maximum eigenvalue real part function to obtain the critical value of the parameters.Root-locus analysis is employed to analyze the impact of changes in the phase-locked loop,short-circuit ratio,and blade inertia on the system stability.Lastly,the accuracy of the small-signal model and the real and imaginary parts of the calculated dominant poles in the theoretical analysis are verified using PSCAD/EMTDC.
基金the National Natural Science Foundation of China under Grant 52007071 and 51907073the China Postdoctoral Science Foundation under Grant 3004131154 and 2020M672355the Applied Basic Frontier Program of Wuhan under Grant 2020010601012207。
文摘To lower the difficulty of fault protection,a doubly-fed induction machine based shipboard propulsion system(DFIM-SPS)that is partially power decoupled is presented.In such an intrinsically safe SPS architecture,a synchronous generator(SG)is employed for power generation,and the accuracy of the parameters of power generation unit(PGU)plays an important role in SPS stable operation.In this paper,the PGU parameter deviations are studied to evaluate the effects on system performance.The models of salient-pole SG,type DC1A excitation system(EXS)and DFIM are illustrated first.Besides,the corresponding control scheme is explained.For the 16 important parameters of PGU,up to 40%of parameter deviations are applied to implement parameter sensitivity analysis.Then,simulation studies are carried out to evaluate the parameter deviation effects on system performance in detail.By defining three parameter deviation effect indicators(PDEIs),the effects on the PGU output variables,which are the terminal voltage and output active power,are studied.Moreover,the increasing rates of PDEIs with different degrees of parameter deviations for the key parameters are analyzed.Furthermore,the overall system performance is investigated for the two most influential PGU parameters.This paper provides some vital clues on SG and EXS parameter identification for DFIM-SPS.
基金This work was supported in part by the National Natural Science Foundation of China(NSFC)under Grants 51707079 and 51877093in part by the National Key Research and Development Program of China(Project ID:YS2018YFGH000200)in part by the Fundamental Research Funds for the Central Universities(Project ID:2019kfyXMBZ031).
文摘The aim of this paper is to investigate an adaptive sensorless direct voltage control(DVC)strategy for the stand-alone ship shaft brushless doubly-fed induction generators(BDFIGs).The proposed new rotor position observer using the space vector flux relations of BDFIG may achieve the desired voltage control of the power winding(PW)in terms of magnitude and frequency,without any speed/position sensors.The proposed algorithm does not require any additional observers for obtaining the generator speed.The proposed technique can directly achieve the desired DVC based on the estimated rotor position,which may reduce the overall system cost.The stability analysis of the proposed observer is investigated and confirmed with the concept of quadratic Lyapunov function and using the multi-model representation.In addition,the sensitivity analysis of the presented method is confirmed under different issues of parameter uncertainties.Comprehensive results from both simulation and experiments are realized with a prototype wound-rotor BDFIG,which demonstrate the capability and efficacy of the proposed sensorless DVC strategy with good transient behavior under different operating conditions.Furthermore,the analysis confirms the robustness of the proposed observer via the machine parameter changes.
基金supported by the National Natural Science Foundation of China(Grant No.51307124)the Major Program of the National Natural Science Foundation of China(Grant No.51190105)
文摘A novel transient rotor current control scheme is proposed in this paper for a doubly-fed induction generator(DFIG)equipped with a superconducting magnetic energy storage(SMES) device to enhance its transient voltage and frequency support capacity during grid faults. The SMES connected to the DC-link capacitor of the DFIG is controlled to regulate the transient dc-link voltage so that the whole capacity of the grid side converter(GSC) is dedicated to injecting reactive power to the grid for the transient voltage support. However, the rotor-side converter(RSC) has different control tasks for different periods of the grid fault. Firstly, for Period I, the RSC injects the demagnetizing current to ensure the controllability of the rotor voltage. Then, since the dc stator flux degenerates rapidly in Period II, the required demagnetizing current is low in Period II and the RSC uses the spare capacity to additionally generate the reactive(priority) and active current so that the transient voltage capability is corroborated and the DFIG also positively responds to the system frequency dynamic at the earliest time. Finally, a small amount of demagnetizing current is provided after the fault clearance. Most of the RSC capacity is used to inject the active current to further support the frequency recovery of the system. Simulations are carried out on a simple power system with a wind farm. Comparisons with other commonly used control methods are performed to validate the proposed control method.
文摘The performance characteristics,particularly the starting performance of direct line-fed induction motors,which are mainly influenced by the design of the rotor,are crucial considerations for end-users.It is quite a challenging issue for motor manufacturers to enhance the starting performance of existing mass-produced motors with minimal modifications and expenses.In this paper,a simple and cost-effective method to improve the starting performance of a commercial squirrel-cage induction motor(SCIM)is proposed.The influence of geometric parameters of the end-ring on the performance characteristics,including starting(locked rotor)torque,pull-up and break down torque,starting current,rotor electric parameters,current density,power losses,and efficiency have been comprehensively investigated.It has been revealed that among the other end-ring design parameters,the ring thickness has a significant effect on the performance characteristics.An optimal end-ring thickness is determined,and its performance characteristics have been compared to those of its initial counterpart.Numeric and parametric analyses have been conducted using a 2D time-stepping finite element method(FEM).The FEM results were validated using experimental measurements obtained from an 11 kW SCIM prototype.
基金supported by a grant from the National Research Foundation(NRF)of Korea funded by the Korean Government,No.NRF-2022R1A2C1004022(to CM)。
文摘Multiple sclerosis is a chronic autoimmune disease of the central nervous system and is generally considered to be a non-traumatic,physically debilitating neurological disorder.In addition to experiencing motor disability,patients with multiple sclerosis also experience a variety of nonmotor symptoms,including cognitive deficits,anxiety,depression,sensory impairments,and pain.However,the pathogenesis and treatment of such non-motor symptoms in multiple scle rosis are still under research.Preclinical studies for multiple sclerosis benefit from the use of disease-appropriate animal models,including experimental autoimmune encephalomyelitis.Prior to understanding the pathophysiology and developing treatments for non-motor symptoms,it is critical to chara cterize the animal model in terms of its ability to replicate certain non-motor features of multiple sclerosis.As such,no single animal model can mimic the entire spectrum of symptoms.This review focuses on the non-motor symptoms that have been investigated in animal models of multiple sclerosis as well as possible underlying mechanisms.Further,we highlighted gaps in the literature to explain the nonmotor aspects of multiple sclerosis in expe rimental animal models,which will serve as the basis for future studies.
文摘The harmonics that appear in the squirrel cage asynchronous machine have been discussed in great detail in the literature for a long time. However, the systematization of the phenomenon is still pending, so we made an attempt to fill this gap in the previous parts of our study by elaborating formulas for calculation of parasitic torques. It was a general demand among those who work in this field towards the author to verify his formulas with measurements. In the literature, it seems,only one detailed, purposeful series of measurements has been published so far, the purpose of which was to investigate the effect of the number of rotor slots on the torque-speed characteristic curve of the machine. The main goal of this study is to verify the correctness of the formulas by comparing them with the referred series of measurements. Relying on this, the expected synchronous parasitic torques were developed for the frequently used rotor slot numbers-as a design guide for the engineer.Thus, together with our complete table for radial magnetic pull published in our previous work, the designer has all the principles, data and formulas available for the right number of rotor slots for his given machine and for the drive system. This brings this series of papers to an end.
基金The authors highly acknowledge the technology financial assistance provided by Jiangsu Frontier Electric Technology Co.,Ltd.(KJ202003).
文摘In order to solve the problems of rotor overvoltage,overcurrent and DC side voltage rise caused by grid voltage drops,a coordinated control strategy based on symmetrical and asymmetrical low voltage ride through of rotor side converter of the doubly-fed generator is proposed.When the power grid voltage drops symmetrically,the generator approximate equation under steady-state conditions is no longer applicable.Considering the dynamic process of stator current excitation,according to the change of stator flux and the depth of voltage drop,the system can dynamically provide reactive power support for parallel nodes and suppress the rise of DC side voltage and rotor over-current.When the grid voltage drops asymmetrically,the positive and negative sequence components are separated in the rotating coordinate system.The doubly fed generator model is established to suppress the rotor positive sequence current and negative sequence current respectively.At the same time,the output voltage limit of the converter is discussed,and the reference value is adjusted within the allowable output voltage range.In order to adapt to the occurrence of different types of power grid faults and complex operating conditions,a fast switching module of fault type detection and rotor control mode is designed to detect the type of power grid faults and voltage drop depth in real time and switch the rotor side control mode dynamically.Finally,the simulation model of the doubly fed wind turbine is constructed in Matlab/Simulink.The simulation results verify that the proposed control strategy can improve the low-voltage ride through performance of the system when dealing with the symmetrical and asymmetric voltage drop of the power grid and identify the power grid fault type and provide the correct control strategy.
文摘Permanent magnet synchronous motor(PMSM)speed control systems with conventional linear active disturbance rejection control(CLADRC)strategy encounter issues regarding the coupling between dynamic response and disturbance suppression and have poor performance in suppressing complex nonlinear disturbances.In order to address these issues,this paper proposes an improved two-degree-of-freedom LADRC(TDOF-LADRC)strategy,which can enhance the disturbance rejection performance of the system while decoupling entirely the system's dynamic and anti-disturbance performance to boost the system robustness and simplify controller parameter tuning.PMSM models that consider total disturbances are developed to design the TDOF-LADRC speed controller accurately.Moreover,to evaluate the control performance of the TDOF-LADRC strategy,its stability is proven,and the influence of each controller parameter on the system control performance is analyzed.Based on it,a comparison is made between the disturbance observation ability and anti-disturbance performance of TDOF-LADRC and CLADRC to prove the superiority of TDOF-LADRC in rejecting disturbances.Finally,experiments are performed on a 750 W PMSM experimental platform,and the results demonstrate that the proposed TDOF-LADRC exhibits the properties of two degrees of freedom and improves the disturbance rejection performance of the PMSM system.
基金supported in part by the National Natural Science Foundations of China under Grants 52277050 and 51877093the fund from Science,Technology,Shenzhen International Collaboration under Grant GJHZ20210705142539007+1 种基金the Key Research and Development Program of Sichuan Province under Grant 2021YFG0081the fund from Science,Technology and Innovation Commission of Shenzhen Municipality under Grant JCYJ20190809101205546。
文摘Nested-loop secondary linear doubly-fed machine(NLS-LDFM) is a novel linear machine evolved from rotary brushless doubly-fed induction machine, which has a good application prospect in linear metro. In order to analyze the performance of NLS-LDFM, the mechanism and action rules of end effects are investigated in this paper. Firstly, the mechanism of static and dynamic end effects is analyzed in aspect of direct coupling, winding asymmetry and transient secondary current. Furthermore, based on the winding theory for short primary linear machines, the machine parameters are established qualitatively considering pulsating magnetic field of NLS-LDFM. Finally, the NLS-LDFM performance analysis is supplemented by the finite element algorithm(FEA) simulation and experiments under different operating conditions.
文摘Kinesin-1 motor protein is a homodimer containing two identical motor domains connected by a common long coiledcoil stalk via two flexible neck linkers. The motor can step on a microtubule with a velocity of about 1 μm·s-1and an attachment duration of about 1 s under physiological conditions. The available experimental data indicate a tradeoff between velocity and attachment duration under various experimental conditions, such as variation of the solution temperature,variation of the strain between the two motor domains, and so on. However, the underlying mechanism of the tradeoff is unknown. Here, the mechanism is explained by a theoretical study of the dynamics of the motor under various experimental conditions, reproducing quantitatively the available experimental data and providing additional predictions. How the various experimental conditions lead to different decreasing rates of attachment duration versus velocity is also explained.
文摘Objective: In the manuscript titled “Liquid subcutaneous Levodopa-Carbidopa ND0612 effects on motor symptoms in individuals with Parkinson’s Disease: A systematic review and meta-analysis”, the objective was to conduct a systematic review with meta-analysis to investigate the effects ND0612 24-hour dosing regimen has on motor symptoms in individuals with Parkinson’s Disease (PD). Introduction: ND0612 is a novel minimally invasive continuous subcutaneous delivery system of liquid Levodopa-Carbidopa being investigated for the treatment of PD in individuals experiencing motor symptoms. Methods: A systematic literature search was conducted in PubMed, Cochrane, and EBSCO databases to identify randomized controlled trials investigating the effects of ND0612 on motor symptoms in individuals with PD. Outcomes included the Unified Parkinson’s Disease Rating Scale (UPDRS) Part II and Part III scores. Methodological quality was assessed using the Cochrane Grading of Recommendations Assessment, Development, and Evaluation approach. Meta-analysis was performed using a random effects model with the DerSimonian and Laird method to estimate the effects of the ND0612 24-hour dosing regimen on UPDRS Part II and Part III scores. Results: Three studies were included in our review. There were statistically significant reductions in UPDRS Part II scores (mean difference (MD) −3.299;95% confidence interval (CI) −3.438, −3.159) and in UPDRS Part III scores (MD −12.695;95% CI −24.428, −0.962) in the ND0612 24-hour dosing regimen. Results were based on very low certainty of evidence. Conclusion: Based on very low certainty evidence, the ND0612 24-hour dosing regimen is effective at improving motor symptoms in individuals with PD. Our findings suggest that ND0612 is more effective at improving UPDRS Part II and Part III scores in individuals with PD than other pharmacological and non-pharmacological treatments, warranting further study.
文摘VFT (variable frequency transformer) has been recently used as art alternative to HVDC (high voltage direct current) to control power flow between asynchronous networks. VFT consumes less reactive power than a back-to-back HVDC system, provides faster initial transient recovery, and has better natural damping capability. VFT is simply a DFIM (doubly-fed induction machine) where the machine torque controls the power flow from stator to rotor and vice versa. The main disadvantage of this VFT is the slip rings and brushes required for the rotor circuit, especially in bulk power transmission. The BDFM (brushless doubly-fed machine) with nested cage rotor machine is proved to be a comparable alternative to conventional DFIM in many applications with the advantage that all windings being in the stator frame with fixed output terminals. In this paper, the BDFM is used as a BVFT (brushless variable frequency transformer). A prototype machine is designed and simulated to verify the system validity.
文摘Application of a DFIG (doubly-fed induction generator), which is one of adjustable speed generators, to a gas engine cogeneration system has been investigated. To operate during a blackout as an emergency power supply is one of important roles for the gas engine eogeneration system. In the case of conventional constant speed of synchronous generator, the amount of the allowed step load is limited to around 30% of the rated power. On the other hand, DFIG is expected to increase the amount of step load during the stand-alone operation. In this paper, it has been demonstrated that an increase in the gas engine speed resulted in an increase in the maximum amount of step load using experimental equipment with a real gas engine. It has been concluded that the proposed system can improve the performance of an emergency power supply at step-loading.
基金supported by Defence Innovative Research Program(DIRP)Grant(PA No.9015102335)from Defence Research&Technology Office,Ministry of Defence,Singapore。
文摘Background:Excessive heat exposure can lead to hyperthermia in humans,which impairs physical performance and disrupts cognitive function.While heat is a known physiological stressor,it is unclear how severe heat stress affects brain physiology and function.Methods:Eleven healthy participants were subjected to heat stress from prolonged exercise or warm water immersion until their rectal temperatures(T_(re))attained 39.5℃,inducing exertional or passive hyperthermia,respectively.In a separate trial,blended ice was ingested before and during exercise as a cooling strategy.Data were compared to a control condition with seated rest(normothermic).Brain temperature(T_(br)),cerebral perfusion,and task-based brain activity were assessed using magnetic resonance imaging techniques.Results:T_(br)in motor cortex was found to be tightly regulated at rest(37.3℃±0.4℃(mean±SD))despite fluctuations in T_(re).With the development of hyperthermia,T_(br)increases and dovetails with the rising T_(re).Bilateral motor cortical activity was suppressed during high-intensity plantarflexion tasks,implying a reduced central motor drive in hyperthermic participants(T_(re)=38.5℃±0.1℃).Global gray matter perfusion and regional perfusion in sensorimotor cortex were reduced with passive hyperthermia.Executive function was poorer under a passive hyperthermic state,and this could relate to compromised visual processing as indicated by the reduced activation of left lateral-occipital cortex.Conversely,ingestion of blended ice before and during exercise alleviated the rise in both T_(re)and T_(bc)and mitigated heat-related neural perturbations.Conclusion:Severe heat exposure elevates T_(br),disrupts motor cortical activity and executive function,and this can lead to impairment of physical and cognitive performance.