The chain/wire rope/chain combination is a common choice for mooring offshore floating platforms. However, data of the drag coefficients of chain links are rather limited, resulting in uncertainties with the calculati...The chain/wire rope/chain combination is a common choice for mooring offshore floating platforms. However, data of the drag coefficients of chain links are rather limited, resulting in uncertainties with the calculations of the drag force, and hence the damping of the mooring system. In this paper, the importance of the selection of the drag coefficient is first investigated. The computational fluid dynamics(CFD) method is then used to determine the drag coefficients of a studless chain under steady flows. Numerical model validation is first completed by simulating a smooth circular cylinder under steady flows. In particular, the performance of different turbulence models is assessed through the comparisons between the calculations and the experimental results. The large eddy simulation(LES) model is finally selected for the simulation of steady flows past a chain. The effects of the Reynolds number on the drag coefficient of a stud-less chain is also studied. The results show that the calculated drag coefficients of a stud-less chain are fairly consistent with the available experimental data.展开更多
The molecular biomechanics of DNA ejection from bacteriophage is of interest to not only fundamental biological understandings but also practical applications such as the design of advanced site-specific and controlla...The molecular biomechanics of DNA ejection from bacteriophage is of interest to not only fundamental biological understandings but also practical applications such as the design of advanced site-specific and controllable drug delivery systems. In this paper, we analyze the viscous motion of a semiflexible polymer chain coming out of a strongly confined space as a model to investigate the effects of various structure confinements and frictional resistances encountered during the DNA ejection process. The theoretically predicted relations between the ejection speed, ejection time, ejection length, and other physical parameters, such as the phage type, total genome length and ionic state of external buffer solutions, show excellent agreement with in vitro experimental observations in the literature.展开更多
基金financial support for the PhD study from GL-Nobel Denton based in London
文摘The chain/wire rope/chain combination is a common choice for mooring offshore floating platforms. However, data of the drag coefficients of chain links are rather limited, resulting in uncertainties with the calculations of the drag force, and hence the damping of the mooring system. In this paper, the importance of the selection of the drag coefficient is first investigated. The computational fluid dynamics(CFD) method is then used to determine the drag coefficients of a studless chain under steady flows. Numerical model validation is first completed by simulating a smooth circular cylinder under steady flows. In particular, the performance of different turbulence models is assessed through the comparisons between the calculations and the experimental results. The large eddy simulation(LES) model is finally selected for the simulation of steady flows past a chain. The effects of the Reynolds number on the drag coefficient of a stud-less chain is also studied. The results show that the calculated drag coefficients of a stud-less chain are fairly consistent with the available experimental data.
基金supported by the National Natural Science Foundation of China (11032006, 11072094, and 11121202)the PhD Program Foundation of the Ministry of Education of China (20100211110022)+1 种基金New Century Excellent Talents in University (NCET-10-0445)supported by the National Science Foundation through grant CMMI-1028530 to Brown University
文摘The molecular biomechanics of DNA ejection from bacteriophage is of interest to not only fundamental biological understandings but also practical applications such as the design of advanced site-specific and controllable drug delivery systems. In this paper, we analyze the viscous motion of a semiflexible polymer chain coming out of a strongly confined space as a model to investigate the effects of various structure confinements and frictional resistances encountered during the DNA ejection process. The theoretically predicted relations between the ejection speed, ejection time, ejection length, and other physical parameters, such as the phage type, total genome length and ionic state of external buffer solutions, show excellent agreement with in vitro experimental observations in the literature.
