Objective:To observe the clinical efficacy of 30%supramolecular salicylic acid combined with Yufa spray dressing in the treatment of moderate to severe seborrheic dermatitis(seborrheic dermatitis of the scalp,SDS).Met...Objective:To observe the clinical efficacy of 30%supramolecular salicylic acid combined with Yufa spray dressing in the treatment of moderate to severe seborrheic dermatitis(seborrheic dermatitis of the scalp,SDS).Methods:From January 2020 to December 2021,150 patients with SDS,who were treated in the Dermatology Clinic of the First Affiliated Hospital of Xi’an Medical University,were randomly divided into two groups,a treatment group and a control group,with 75 cases in each group.The treatment group was given 30%supramolecular salicylic acid combined with Yufa spray dressing on the basis of external medicine given to the control group,while the control group was given oral medicine combined with external medicine.Results:The difference in scores of erythema,scales,pruritus,and folliculitis of the treatment group before and after treatment was significant(P<0.01),indicating that supramolecular salicylic acid combined with Yufa spray dressing can relieve the symptoms of SDS.The difference in scores of erythema of the control group before and after treatment was significant as well(P<0.05),indicating that traditional antibiotics are also effective in treating SDS;however,there was no significant difference(P>0.05)in the scores of other signs and symptoms,such as scales,pruritus,and folliculitis,before and after treatment,indicating that traditional antibiotics have no obvious curative effect on SDS.After 12 weeks of treatment,the improvement in erythema,scaling,and folliculitis was significantly greater in the treatment group compared with the control group(P<0.05).Curative effect comparison showed that the total effective rate of the treatment group was 80.00%,compared with 25.67%of the control group,and the difference was statistically significant(P<0.05).Conclusion:30%supramolecular salicylic acid combined with Yufa spray dressing can significantly improve the therapeutic effect in moderate to severe SDS;the recurrence rate is lower,the course of treatment is shorted,and patients generally feel better;thus,it is a new option for the treatment of dermatitis.展开更多
It was tried to microencapsulate camellia oil using heterocoagulation between fatty acid dissolved in camellia oil and chitosan dissolved in the continuous water phase. Oleic acid as a fatty acid was dissolved in came...It was tried to microencapsulate camellia oil using heterocoagulation between fatty acid dissolved in camellia oil and chitosan dissolved in the continuous water phase. Oleic acid as a fatty acid was dissolved in camellia oil in order to certainly form the microcapsule shell made from oleic acid and chitosan. The microcapsules were observed with optical microscope and characterized about the diameters, ζ-potential, FTIR analysis and adhesion feature on human hair. Microcapsules with the mean diameter in the range from ca. 1.5 μm to 4.5 μm could be prepared with the preparation method presented in this study. The oil droplets of camellia oil charged negatively to be -54.6 mV and the microcapsules charged positively to be 59.6 mV. The microcapsules adhered well on the negatively charged human hair and were kept stably before and after drying at room temperature for 24 h and blowing.展开更多
文摘Objective:To observe the clinical efficacy of 30%supramolecular salicylic acid combined with Yufa spray dressing in the treatment of moderate to severe seborrheic dermatitis(seborrheic dermatitis of the scalp,SDS).Methods:From January 2020 to December 2021,150 patients with SDS,who were treated in the Dermatology Clinic of the First Affiliated Hospital of Xi’an Medical University,were randomly divided into two groups,a treatment group and a control group,with 75 cases in each group.The treatment group was given 30%supramolecular salicylic acid combined with Yufa spray dressing on the basis of external medicine given to the control group,while the control group was given oral medicine combined with external medicine.Results:The difference in scores of erythema,scales,pruritus,and folliculitis of the treatment group before and after treatment was significant(P<0.01),indicating that supramolecular salicylic acid combined with Yufa spray dressing can relieve the symptoms of SDS.The difference in scores of erythema of the control group before and after treatment was significant as well(P<0.05),indicating that traditional antibiotics are also effective in treating SDS;however,there was no significant difference(P>0.05)in the scores of other signs and symptoms,such as scales,pruritus,and folliculitis,before and after treatment,indicating that traditional antibiotics have no obvious curative effect on SDS.After 12 weeks of treatment,the improvement in erythema,scaling,and folliculitis was significantly greater in the treatment group compared with the control group(P<0.05).Curative effect comparison showed that the total effective rate of the treatment group was 80.00%,compared with 25.67%of the control group,and the difference was statistically significant(P<0.05).Conclusion:30%supramolecular salicylic acid combined with Yufa spray dressing can significantly improve the therapeutic effect in moderate to severe SDS;the recurrence rate is lower,the course of treatment is shorted,and patients generally feel better;thus,it is a new option for the treatment of dermatitis.
文摘It was tried to microencapsulate camellia oil using heterocoagulation between fatty acid dissolved in camellia oil and chitosan dissolved in the continuous water phase. Oleic acid as a fatty acid was dissolved in camellia oil in order to certainly form the microcapsule shell made from oleic acid and chitosan. The microcapsules were observed with optical microscope and characterized about the diameters, ζ-potential, FTIR analysis and adhesion feature on human hair. Microcapsules with the mean diameter in the range from ca. 1.5 μm to 4.5 μm could be prepared with the preparation method presented in this study. The oil droplets of camellia oil charged negatively to be -54.6 mV and the microcapsules charged positively to be 59.6 mV. The microcapsules adhered well on the negatively charged human hair and were kept stably before and after drying at room temperature for 24 h and blowing.
