Pyrophyllite (H2Al2,Si4 O22, ) dust (P-dust) is a mixture of silica (10-40% ), differentproportions of a luminium oxide (Al2O3 ), and various metal compounds. People with occupa-tions known to be associated with expos...Pyrophyllite (H2Al2,Si4 O22, ) dust (P-dust) is a mixture of silica (10-40% ), differentproportions of a luminium oxide (Al2O3 ), and various metal compounds. People with occupa-tions known to be associated with exposure to P-dust include miners, other industrial workersand persons engaged in artistic carving. Currently, little is known about pyrophyllite pneumo-coniosis from P-dust. This study was designed to investigate the hazardous effects of P-dustand to suggest a maximum allowable concentration (MAC) of the dust.This.study included four parts: (i) Occupational epidemiology surveys in 781 workersfrom 1 pyrophyllite mine (PM) and four pyrophyllite carving mills (PCM), with a registra-tion rate of 98 %. (ii) In vitro studies: Six groups of rats were expeed to different levels ofP-dust; the cytotoxicity of P-dust on rat alveolar macrophages (AM) was investigated by de-termining the potassium'content of AM and the activity levels of lactate dehydrogenase (LDH)in AM culture fluid. (iii) Mineralogical analysis of P-dust: The contents of silica (SiO2 ), alu-minium (Al), ferrum (Fe), niikel (Ni), zinc (Zn) and copper (Cu) in hath PM-dust andPCMdust were determined. (iv ) Determination of P-dust MAC: Using the life-talbemethod, an investigation of the hygiene standard of P-dust was carried out in 625 workers ex-POSed to either PM-dust or PCM-dust, uPon whom routine radiographs were Performed.The results suggest that the risk of developing pneumoconiosis from pyrophyllite dust issignificantly higher for PM workers than for PCM workers. The prevalence rate of PCM-dustpneumoconiosis is significantly higher in men than in women. The content of SiO2 and AlO3in the mixture of P-dust is the most important factor in the etiology of pyrophyllitosis. De-pending on the different P-dust MAC values, we suggest that 2 rng/m3 and 4 mg/m' shouldbe considered as the MAC for PM-dust and PCM-dust, respectively, and 3 mg/m' fOr P-dust. We believe that establishing different hygiene standards is more accurate even thoughworkers are exposured to the 'same' dust展开更多
矿山粉尘职业危害已成为矿山行业最重要的职业健康问题,对矿山粉尘危害进行风险评估、量化其危害程度是矿山职业卫生工作的重点。为深入了解矿山粉尘职业危害风险评估领域的研究脉络,基于文献计量学角度,采用VOSviewer与CiteSpace软件...矿山粉尘职业危害已成为矿山行业最重要的职业健康问题,对矿山粉尘危害进行风险评估、量化其危害程度是矿山职业卫生工作的重点。为深入了解矿山粉尘职业危害风险评估领域的研究脉络,基于文献计量学角度,采用VOSviewer与CiteSpace软件对中国知网(CNKI)和WOS(Web of Science)收录的矿山粉尘危害风险评估相关文献进行可视化分析,提取高频关键词,进行关键词共现、聚类分析,获得文献的时序特征、研究主体以及热点前沿信息。根据可视化分析结果,从风险评估指标、危害程度等级、评估方法3个方面进行了详细分析和阐述。细化了风险评估流程,分析了矿山粉尘的理化特性和危害因素,进而归纳了风险评估指标,总结了粉尘职业危害程度分级,按照定性、定量和综合评估3种类别梳理了矿山粉尘职业危害风险评估方法,阐释了健康伤害风险评估的量化模型。研究表明:目前国内外在矿山粉尘职业危害风险评估方向进行了大量深入的研究和实践,评估工作取得了较为显著的成效,但矿山各生产环节粉尘至今仍难以彻底遏制,相关研究理论机制尚未成熟,评估指标影响因素冗杂、危害程度分级缺乏依据、评估方法存在主观不确定性,矿山粉尘职业危害风险评估体系有待系统研究,粉尘危害风险分析及预警平台尚需探索构建。未来,需进一步完善矿山粉尘职业危害风险评估相关法律法规;科学、合理地选择风险评估指标,简化评估工作环节,实现良好的实用效益;突破现有方法局限,建立适用的数据信息论风险评估模型,为矿山粉尘治理提供有效依据;积极应用云计算、大数据等新技术,实现粉尘监测—风险评估—智能防控一体化系统建设。展开更多
In order to assess the cement dust levels at the factory of the Beninese Cement Industry (BCI), at Xwlacodji, seven sampling stations (numbered 1 to 7) were set inside the industry and nine (numbered 8 to 16) were set...In order to assess the cement dust levels at the factory of the Beninese Cement Industry (BCI), at Xwlacodji, seven sampling stations (numbered 1 to 7) were set inside the industry and nine (numbered 8 to 16) were set around the factory in January, February, August and December. With the method of stainless steel plate according to NFX 43-007 AFNOR Standard, the different stations were monitored daily for dust collection all month long. The results revealed that the mean values of cement dusts inside BCI in g/m2/day ranged from 1.608 to 8.752 in January, from 1.13068 to 6.14924 in February, from 0.9654 to 5.2502 for August and from 1.7220 to 9.3620 for December. With regard to outside BCI, the mean values of dusts rose from 8.8760 to 18.9620 in December. The lowest mean values 3.2719 and 4.4124 were respectively recorded in February and August whereas the highest values 17.7309 and 18.9620 were respectively recorded in January and December. Our study revealed month variation in cement dust deposition with the highest values in December and January and the lowest values in February and August. It was observed that the content in cement dusts recorded outside the cement industry were extremely higher than those recorded inside the cement industry. The values in the present study have far exceeded all the international safety values (1 g/m2/day for AFNOR and 350 mg/m2/day TA-Luft) and could pose health hazards. Therefore protective measures are suggested to mitigate the risk of occupational hazards for the cement industrial workers.展开更多
文摘Pyrophyllite (H2Al2,Si4 O22, ) dust (P-dust) is a mixture of silica (10-40% ), differentproportions of a luminium oxide (Al2O3 ), and various metal compounds. People with occupa-tions known to be associated with exposure to P-dust include miners, other industrial workersand persons engaged in artistic carving. Currently, little is known about pyrophyllite pneumo-coniosis from P-dust. This study was designed to investigate the hazardous effects of P-dustand to suggest a maximum allowable concentration (MAC) of the dust.This.study included four parts: (i) Occupational epidemiology surveys in 781 workersfrom 1 pyrophyllite mine (PM) and four pyrophyllite carving mills (PCM), with a registra-tion rate of 98 %. (ii) In vitro studies: Six groups of rats were expeed to different levels ofP-dust; the cytotoxicity of P-dust on rat alveolar macrophages (AM) was investigated by de-termining the potassium'content of AM and the activity levels of lactate dehydrogenase (LDH)in AM culture fluid. (iii) Mineralogical analysis of P-dust: The contents of silica (SiO2 ), alu-minium (Al), ferrum (Fe), niikel (Ni), zinc (Zn) and copper (Cu) in hath PM-dust andPCMdust were determined. (iv ) Determination of P-dust MAC: Using the life-talbemethod, an investigation of the hygiene standard of P-dust was carried out in 625 workers ex-POSed to either PM-dust or PCM-dust, uPon whom routine radiographs were Performed.The results suggest that the risk of developing pneumoconiosis from pyrophyllite dust issignificantly higher for PM workers than for PCM workers. The prevalence rate of PCM-dustpneumoconiosis is significantly higher in men than in women. The content of SiO2 and AlO3in the mixture of P-dust is the most important factor in the etiology of pyrophyllitosis. De-pending on the different P-dust MAC values, we suggest that 2 rng/m3 and 4 mg/m' shouldbe considered as the MAC for PM-dust and PCM-dust, respectively, and 3 mg/m' fOr P-dust. We believe that establishing different hygiene standards is more accurate even thoughworkers are exposured to the 'same' dust
文摘矿山粉尘职业危害已成为矿山行业最重要的职业健康问题,对矿山粉尘危害进行风险评估、量化其危害程度是矿山职业卫生工作的重点。为深入了解矿山粉尘职业危害风险评估领域的研究脉络,基于文献计量学角度,采用VOSviewer与CiteSpace软件对中国知网(CNKI)和WOS(Web of Science)收录的矿山粉尘危害风险评估相关文献进行可视化分析,提取高频关键词,进行关键词共现、聚类分析,获得文献的时序特征、研究主体以及热点前沿信息。根据可视化分析结果,从风险评估指标、危害程度等级、评估方法3个方面进行了详细分析和阐述。细化了风险评估流程,分析了矿山粉尘的理化特性和危害因素,进而归纳了风险评估指标,总结了粉尘职业危害程度分级,按照定性、定量和综合评估3种类别梳理了矿山粉尘职业危害风险评估方法,阐释了健康伤害风险评估的量化模型。研究表明:目前国内外在矿山粉尘职业危害风险评估方向进行了大量深入的研究和实践,评估工作取得了较为显著的成效,但矿山各生产环节粉尘至今仍难以彻底遏制,相关研究理论机制尚未成熟,评估指标影响因素冗杂、危害程度分级缺乏依据、评估方法存在主观不确定性,矿山粉尘职业危害风险评估体系有待系统研究,粉尘危害风险分析及预警平台尚需探索构建。未来,需进一步完善矿山粉尘职业危害风险评估相关法律法规;科学、合理地选择风险评估指标,简化评估工作环节,实现良好的实用效益;突破现有方法局限,建立适用的数据信息论风险评估模型,为矿山粉尘治理提供有效依据;积极应用云计算、大数据等新技术,实现粉尘监测—风险评估—智能防控一体化系统建设。
文摘In order to assess the cement dust levels at the factory of the Beninese Cement Industry (BCI), at Xwlacodji, seven sampling stations (numbered 1 to 7) were set inside the industry and nine (numbered 8 to 16) were set around the factory in January, February, August and December. With the method of stainless steel plate according to NFX 43-007 AFNOR Standard, the different stations were monitored daily for dust collection all month long. The results revealed that the mean values of cement dusts inside BCI in g/m2/day ranged from 1.608 to 8.752 in January, from 1.13068 to 6.14924 in February, from 0.9654 to 5.2502 for August and from 1.7220 to 9.3620 for December. With regard to outside BCI, the mean values of dusts rose from 8.8760 to 18.9620 in December. The lowest mean values 3.2719 and 4.4124 were respectively recorded in February and August whereas the highest values 17.7309 and 18.9620 were respectively recorded in January and December. Our study revealed month variation in cement dust deposition with the highest values in December and January and the lowest values in February and August. It was observed that the content in cement dusts recorded outside the cement industry were extremely higher than those recorded inside the cement industry. The values in the present study have far exceeded all the international safety values (1 g/m2/day for AFNOR and 350 mg/m2/day TA-Luft) and could pose health hazards. Therefore protective measures are suggested to mitigate the risk of occupational hazards for the cement industrial workers.