Background:Despite increasing recognition that health-systems constraints are the fundamental barrier to attaining anti-retroviral therapy(ART)scale-up targets in Sub-Saharan Africa,current discourses are dominated by...Background:Despite increasing recognition that health-systems constraints are the fundamental barrier to attaining anti-retroviral therapy(ART)scale-up targets in Sub-Saharan Africa,current discourses are dominated by a focus on financial sustainability.Utilizing the health system dynamics framework,this study aimed to explore the interactions in health system components and their influence on the sustainability of ART scale-up implementation in Uganda.Methods:This study entailed qualitative organizational case-studies within a two-phased mixed-methods sequential explanatory research design.In Phase One,a survey of 195 health facilities across Uganda which commenced ART services between 2004 and 2009 was conducted.In Phase Two,six health facilities were purposively selected for in-depth examination involving i)In-depth interviews(n=44)ii)and semistructured interviews(n=35).Qualitative data was analyzed by coding and thematic analysis.Descriptive statistics were managed in STATA(v 13).Results:Five dynamic interactions in ART program sustainability drivers were identified;i)Failure to update basic ART program records contributed to chronic ART medicines stock-outs ii)Health workforce shortages and escalating patient volumes prompted adaptations in ART service delivery models iii)Broader governance issues manifested in poor road networks undermined ART medicines supply chains iv)Sustained financing for ART programs was influenced by external donors v)The values associated with the ownership-type of a health facility affected ART service delivery and coverage.Conclusion:The sustainability of ART programs at the facility-level in Uganda is a function of a complex interaction in elements of the health system and must be understood beyond sustaining international funding for ART scale-up.展开更多
Improving freight axle load is the most effective method to improve railway freight capability; based on the imported technologies of railway freight bogie, the 27 t axle load side-frame cross-bracing bogie and sub-fr...Improving freight axle load is the most effective method to improve railway freight capability; based on the imported technologies of railway freight bogie, the 27 t axle load side-frame cross-bracing bogie and sub-frame radial bogie are developed in China. In order to analyze and compare dynamic interactions of the two newly developed heavy-haul freight bogies, we establish a vehi- cle-track coupling dynamic model and use numerical calculation methods for computer simulation. The dynamic performances of the two bogies are simulated separately at various conditions. The results show that at the dipped joint and straight line running conditions, the wheel-rail dynamic interactions of both bogies are basically the same, but at the curve negotiation condition, the wear and the lateral force of the side-frame cross-bracing bogie are much higher than that of the sub-frame radial bogie, and the advantages become more obvious when the curve radius is smaller. The results also indicate that the sub- frame radial bogie has better low-wheel-rail interaction characteristics.展开更多
By modifying friction to the desired level,the application of friction modifiers(FMs)has been considered as a promising emerging tool in the railway engineering for increasing braking/traction force in poor adhesion c...By modifying friction to the desired level,the application of friction modifiers(FMs)has been considered as a promising emerging tool in the railway engineering for increasing braking/traction force in poor adhesion conditions and mitigating wheel/rail interface deterioration,energy consumption,vibration and noise.Understanding the effectiveness of FMs in wheel–rail dynamic interactions is crucial to their proper applications in practice,which has,however,not been well explained.This study experimentally investigates the effects of two types of top-of-rail FM,i.e.FM-A and FM-B,and their application dosages on wheel–rail dynamic interactions with a range of angles of attack(AoAs)using an innovative well-controlled V-track test rig.The tested FMs have been used to provide intermediate friction for wear and noise reduction.The effectiveness of the FMs is assessed in terms of the wheel–rail adhesion characteristics and friction rolling induced axle box acceleration(ABA).This study provides the following new insights into the study of FM:the applications of the tested FMs can both reduce the wheel–rail adhesion level and change the negative friction characteristic to positive;stick–slip can be generated in the V-Track and eliminated by FM-A but intensified by FM-B,depending on the dosage of the FMs applied;the negative friction characteristic is not a must for stick–slip;the increase in ABA with AoA is insignificant until stick–slip occurs and the ABA can thus be influenced by the applications of FM.展开更多
Maintaining the integrity and longevity of structures is essential in many industries,such as aerospace,nuclear,and petroleum.To achieve the cost-effectiveness of large-scale systems in petroleum drilling,a strong emp...Maintaining the integrity and longevity of structures is essential in many industries,such as aerospace,nuclear,and petroleum.To achieve the cost-effectiveness of large-scale systems in petroleum drilling,a strong emphasis on structural durability and monitoring is required.This study focuses on the mechanical vibrations that occur in rotary drilling systems,which have a substantial impact on the structural integrity of drilling equipment.The study specifically investigates axial,torsional,and lateral vibrations,which might lead to negative consequences such as bit-bounce,chaotic whirling,and high-frequency stick-slip.These events not only hinder the efficiency of drilling but also lead to exhaustion and harm to the system’s components since they are difficult to be detected and controlled in real time.The study investigates the dynamic interactions of these vibrations,specifically in their high-frequency modes,usingfield data obtained from measurement while drilling.Thefindings have demonstrated the effect of strong coupling between the high-frequency modes of these vibrations on drilling sys-tem performance.The obtained results highlight the importance of considering the interconnected impacts of these vibrations when designing and implementing robust control systems.Therefore,integrating these compo-nents can increase the durability of drill bits and drill strings,as well as improve the ability to monitor and detect damage.Moreover,by exploiting thesefindings,the assessment of structural resilience in rotary drilling systems can be enhanced.Furthermore,the study demonstrates the capacity of structural health monitoring to improve the quality,dependability,and efficiency of rotary drilling systems in the petroleum industry.展开更多
The finite element method was used to solve fluid dynamic interaction problems between the crust and mantle of the Earth. To consider different mechanical behaviours, the lithosphere consisting of the crust and upper ...The finite element method was used to solve fluid dynamic interaction problems between the crust and mantle of the Earth. To consider different mechanical behaviours, the lithosphere consisting of the crust and upper mantle was simulated as fluid-saturated porous rocks, while the upper aesthenospheric part of the mantle was simulated as viscous fluids. Since the whole lithosphere was computationally simulated, the dynamic interaction between the crust and the upper mantle was appropriately considered. In particular, the mixing of mantle fluids and crustal fluids was simulated in the corresponding computational model. The related computational simulation results from an example problem demonstrate that the mantle fluids can flow into the crust and mix with the crustal fluids due to the resulting convective flows in the crust-mantle system. Likewise, the crustal fluids can also flow into the upper mantle and mix with the mantle fluids. This kind of fluids mixing and exchange is very important to the better understanding of the governing processes that control the ore body formation and mineralization in the upper crust of the Earth.展开更多
This paper analyses the modal interactions in the nonlinear, size-dependent dynamics of geometrically imperfect microplates. Based on the modified couple stress theory,the equations of motion for the in-plane and out-...This paper analyses the modal interactions in the nonlinear, size-dependent dynamics of geometrically imperfect microplates. Based on the modified couple stress theory,the equations of motion for the in-plane and out-of-plane motions are obtained employing the von Kármán plate theory as well as Kirchhoff's hypotheses by means of the Lagrange equations. The equations of motions are solved using the pseudo-arclength continuation technique and direct timeintegration method. The system parameters are tuned to the values associated with modal interactions, and then nonlinear resonant responses and energy transfer are analysed.Nonlinear motion characteristics are shown in the form of frequency-response and force-response curves, time histories, phase-plane portraits, and fast Fourier transforms.展开更多
Using the mean-field theory and Glauber-type stochastic dynamics, we study the dynamic magnetic properties of the mixed spin (2, 5/2) Ising system for the antiferromagnetic/antiferromagnetic (AFM/AFM) interactions...Using the mean-field theory and Glauber-type stochastic dynamics, we study the dynamic magnetic properties of the mixed spin (2, 5/2) Ising system for the antiferromagnetic/antiferromagnetic (AFM/AFM) interactions on the bilayer square lattice under a time varying (sinusoidal) magnetic field. The time dependence of average magnetizations and the thermal variation of the dynamic magnetizations are examined to calculate the dynamic phase diagrams. The dynamic phase diagrams are presented in the reduced temperature and magnetic field amplitude plane and the effects of interlayer coupling interaction on the critical behavior of the system are investigated. We also investigate the influence of the frequency and find that the system displays richer dynamic critical behavior for higher values of frequency than that of the lower values of it. We perform a comparison with the ferromagnetic/ferromagnetic (FM/FM) and AFM/FM interactions in order to see the effects of AFM/AFM interaction and observe that the system displays richer and more interesting dynamic critical behaviors for the AFM/AFM interaction than those for the FM/FM and AFM/FM interactions.展开更多
Generation of attosecond electromagnetic (EM) pulses and the associated electron dynamics are studied using particle-in-cell simulations of relativistic laser pulses interacting with over-dense plasma foil targets. ...Generation of attosecond electromagnetic (EM) pulses and the associated electron dynamics are studied using particle-in-cell simulations of relativistic laser pulses interacting with over-dense plasma foil targets. The inter- action process is found to be so complicated even in the situation of utilizing driving laser pulses of only one cycle. Two electron bunches closely involved in the laser-driven wavebreaking process contribute to attosecond EM pulses through the coherent synchrotron emission process whose spectra are found to follow an exponential decay rule. Detailed investigations of electron dynamics indicate that the early part of the reflected EM emission is the high-harmonics produced through the relativistic oscillating mirror mechanism. High harmonics are also found to be generated through the Bremsstrahlung radiation by one electron bunch that participates in the wavebreaking process and decelerates when it experiences the local wavebreaking-generated high electrostatic field in the moving direction.展开更多
The train-bridge dynamic interaction problem began with the development of railway technology, and requires an evaluation method for bridge design in order to ensure the safety and stability of the bridge and the runn...The train-bridge dynamic interaction problem began with the development of railway technology, and requires an evaluation method for bridge design in order to ensure the safety and stability of the bridge and the running train. This problem is studied using theoretical analysis, numerical simulation, and experimental study. In the train-bridge dynamic interaction system proposed in this paper, the train vehicle model is established by the rigid-body dynamics method, the bridge model is established by the finite element method, and the wheel/rail vertical and lateral interaction are simulated by the corresponding assumption and the Kalker linear creep theory, respectively. Track irregularity, structure deformation, wind load, collision load, structural damage, foundation scouring, and earthquake action are regarded as the excitation for the system. The train-bridge dynamic interaction system is solved by inter-history iteration. A case study of the dynamic response of a CRH380BL high-speed train running through a standard-design bridge in China is discussed. The dynamic responses of the vehicle and of the bridge subsystems are obtained for speeds ranging from 200 km-b-1 to 400 km.h-1, and the vibration mechanism are analyzed.展开更多
Taking the effect of finite soil layers below pile end into account,the longitudinal dynamic response of pile undergoing dynamic loading in layered soil was theoretically investigated.Firstly,finite soil layers below ...Taking the effect of finite soil layers below pile end into account,the longitudinal dynamic response of pile undergoing dynamic loading in layered soil was theoretically investigated.Firstly,finite soil layers below pile end are modeled as virtual soil pile whose cross-section area is the same as that of the pile and the soil layers surrounding the pile are described by the plane strain model.Then,by virtue of Laplace transform and impedance function transfer method,the analytical solution of longitudinal dynamic response at the pile head in frequency domain is yielded.Also,the semi-analytical solution in time domain undergoing half-cycle sine pulse at the pile head is obtained by means of inverse Laplace transform.Based on these solutions,a parametric study is conducted to analyze emphatically the effects of parameters of soil below pile end on velocity admittance and reflected wave signals at the pile head.Additionally,a comparison with other models with different supporting conditions from soil below pile end is performed to verify the model presented.展开更多
Due to the wide applications of arches in underground protective structures, dynamic analysis of circular arches including soil-structure interactions is important. In this paper, an exact solution of the forced vibra...Due to the wide applications of arches in underground protective structures, dynamic analysis of circular arches including soil-structure interactions is important. In this paper, an exact solution of the forced vibration of circular arches subjected to subsurface denotation forces is obtained. The dynamic soil-structure interaction is considered with the introduction of an interfacial damping between the structure element and the surrounding soil into the equa- tion of motion. By neglecting the influences of shear, rotary inertia and tangential forces and assuming the arch incompressible, the equations of motion of the buried arches were set up. Analytical solutions of the dynamic responses of the protective arches were deduced by means of modal super- position. Arches with different opening angles, acoustic impedances and rise-span ratios were analyzed to discuss their influences on an arch. The theoretical analysis suggests blast loads for elastic designs and predicts the potential failure modes for buried protective arches.展开更多
BACKGROUND Nursing practices based on the dynamic interaction model have been shown to be superior to generic nursing practices.However,whether this model is effective in patients recovering from intracranial aneurysm...BACKGROUND Nursing practices based on the dynamic interaction model have been shown to be superior to generic nursing practices.However,whether this model is effective in patients recovering from intracranial aneurysm surgery is not well studied.AIM To investigate the effect of nursing based on a dynamic interaction model on functional rehabilitation of patients after aneurysm surgery.METHODS A total of 86 cases in our hospital with intracranial aneurysm from April 2019 to April 2021,were selected and divided into the study group and the control group,with 43 patients in each group.The control group received routine nursing,and the research group received nursing intervention based on a dynamic interaction model.The daily living ability(activities of daily living,ADL),cognitive function(Simple Intelligent Mental State Scale,MMSE),quality of life(Generic Quality of Life Inventory-74,GQOL-74),self-care ability(Exercise of Self-Care Agency scale),incidence of complications,and nursing satisfaction were recorded before and after intervention.RESULTS Before intervention,ADL(52.09±6.44),MMSE(18.03±4.11),and GQOL-74(53.68±4.34)scores in the study group were not significantly different from those in the control group(ADL:50.97±7.32,MMSE:17.59±3.82,GQOL-74:55.06±3.98)(P>0.05).After intervention,ADL(86.12±5.07),MMSE(26.64±2.66),and GQOL-74(83.13±5.67)scores in the study group were higher than those in the control group(ADL:79.81±6.35,MMSE:24.51±3.00,and GQOL-74:77.96±6.27)(P<0.05).Before intervention,self-concept(17.46±4.44),self-care skills(25.22±4.20),self-care knowledge(22.35±4.74),and self-care responsibility(15.06±3.29)scores in the study group was similar to those in the control group(self-concept:16.89±5.53,self-care skills:24.59±4.46,self-care knowledge:21.80±3.61,and self-care responsibility:14.83±3.11)(P>0.05).After the intervention,self-concept(26.01±3.18),self-care skills(37.68±6.05),self-care knowledge(45.56±5.83),and self-care responsibility(22.01±3.77)scores in the study group were higher than those in the control group(self-concept:22.97±3.46,self-care skills:33.02±5.65,selfcare skills knowledge:36.81±5.54,and self-care responsibility:17.97±3.56 points)(P<0.05).The incidence of complications in the study group(4.65%)was lower than that in the control group(18.60%)(P<0.05).Nursing satisfaction in the study group(95.35%)was higher than that in the control group(81.40%)(P<0.05).CONCLUSION Nursing intervention based on a dynamic interaction model can improve postoperative cognitive function,daily living ability,self-care ability,quality of life,and patient satisfaction,while reducing the risk of complications.展开更多
The scattering of plane harmonic P and SV waves by a pair of vertically overlapping lined tunnels buried in an elastic half space is solved using a semi-analytic indirect boundary integration equation method. Then the...The scattering of plane harmonic P and SV waves by a pair of vertically overlapping lined tunnels buried in an elastic half space is solved using a semi-analytic indirect boundary integration equation method. Then the effect of the distance between the two tunnels, the stiffness and density of the lining material, and the incident frequency on the seismic response of the tunnels is investigated. Numerical results demonstrate that the dynamic interaction between the twin tunnels cannot be ignored and the lower tunnel has a significant shielding effect on the upper tunnel for high-frequency incident waves, resulting in great decrease of the dynamic hoop stress in the upper tunnel; for the low-frequency incident waves, in contrast, the lower tunnel can lead to amplification effect on the upper tunnel. It also reveals that the frequency-spectrum characteristics of dynamic stress of the lower tunnel are significantly different from those of the upper tunnel. In addition, for incident P waves in low-frequency region, the soft lining tunnels have significant amplification effect on the surface displacement amplitude, which is slightly larger than that of the corresponding single tunnel.展开更多
Consideration of structure-foundation-soil dynamic interaction is a basic requirement in the evaluation of the seismic safety of nuclear power facilities. An efficient and accurate dynamic interaction numerical model ...Consideration of structure-foundation-soil dynamic interaction is a basic requirement in the evaluation of the seismic safety of nuclear power facilities. An efficient and accurate dynamic interaction numerical model in the time domain has become an important topic of current research. In this study, the scaled boundary finite element method (SBFEM) is improved for use as an effective numerical approach with good application prospects. This method has several advantages, including dimensionality reduction, accuracy of the radial analytical solution, and unlike other boundary element methods, it does not require a fundamental solution. This study focuses on establishing a high performance scaled boundary finite element interaction analysis model in the time domain based on the acceleration unit-impulse response matrix, in which several new solution techniques, such as a dimensionless method to solve the interaction force, are applied to improve the numerical stability of the actual soil parameters and reduce the amount of calculation. Finally, the feasibility of the time domain methods are illustrated by the response of the nuclear power structure and the accuracy of the algorithms are dynamically verified by comparison with the refinement of a large-scale viscoelastic soil model.展开更多
In this work,a method is put forward to obtain the dynamic solution efficiently and accurately for a large-scale train-track-substructure(TTS)system.It is called implicit-explicit integration and multi-time-step solut...In this work,a method is put forward to obtain the dynamic solution efficiently and accurately for a large-scale train-track-substructure(TTS)system.It is called implicit-explicit integration and multi-time-step solution method(abbreviated as mI-nE-MTS method).The TTS system is divided into train-track subsystem and substruc-ture subsystem.Considering that the root cause of low effi-ciency of obtaining TTS solution lies in solving the alge-braic equation of the substructures,the high-efficient Zhai method,an explicit integration scheme,can be introduced to avoid matrix inversion process.The train-track system is solved by implicitly Park method.Moreover,it is known that the requirement of time step size differs for different sub-systems,integration methods and structural frequency response characteristics.A multi-time-step solution is pro-posed,in which time step size for the train-track subsystem and the substructure subsystem can be arbitrarily chosen once satisfying stability and precision demand,namely the time spent for m implicit integral steps is equal to n explicit integral steps,i.e.,mI=nE as mentioned above.The numeri-cal examples show the accuracy,efficiency,and engineering practicality of the proposed method.展开更多
Nowadays,there are many studies conducted in the field of marine hydrodynamics which focus on two vessels traveling and floating in sufficiently close proximity to experience significant interactions.The hydrodynamic ...Nowadays,there are many studies conducted in the field of marine hydrodynamics which focus on two vessels traveling and floating in sufficiently close proximity to experience significant interactions.The hydrodynamic behavior of parallel moving ships in waves is an interesting and important topic of late.A numerical investigation has been carried out for the prediction of wave exciting forces and motion responses of parallel moving ships in regular waves.The numerical solution was based on 3D distribution technique and using the linear wave theory to determine the exciting forces and ship's motion.The speed effects have been considered in the Green function for more realistic results.The numerical computations of wave exciting forces and motion responses were carried out for a Mariner and Series 60 for the purpose of discovering different Froude numbers and different separation distances in head sea conditions.Based on the numerical computations,it was revealed that the sway,roll and yaw have a significant effect due to hydrodynamic interaction.展开更多
Train–track–substructure dynamic interaction is an extension of the vehicle–track coupled dynamics.It contributes to evaluate dynamic interaction and performance between train–track system and its substructures.Fo...Train–track–substructure dynamic interaction is an extension of the vehicle–track coupled dynamics.It contributes to evaluate dynamic interaction and performance between train–track system and its substructures.For the first time,this work devotes to presenting engineering practical methods for modeling and solving such large-scale train–track–substructure interaction systems from a unified viewpoint.In this study,a train consists of several multi-rigid-body vehicles,and the track is modeled by various finite elements.The track length needs only satisfy the length of a train plus boundary length at two sides,despite how long the train moves on the track.The substructures and their interaction matrices to the upper track are established as independent modules,with no need for additionally building the track structures above substructures,and accordingly saving computational cost.Track–substructure local coordinates are defined to assist the confirming of the overlapped portions between the train–track system and the substructural system to effectively combine the cyclic calculation and iterative solution procedures.The advancement of this model lies in its convenience,efficiency and accuracy in continuously considering the vibration participation of multi-types of substructures against the moving of a train on the track.Numerical examples have shown the effectiveness of this method;besides,influence of substructures on train–track dynamic behaviors is illustrated accompanied by clarifying excitation difference of different track irregularity spectrums.展开更多
The formation and evolution of basins in the China continent are closely related to the collages of many blocks and orogenic belts. Based on a large amount of the geological, geophysical, petroleum exploration data an...The formation and evolution of basins in the China continent are closely related to the collages of many blocks and orogenic belts. Based on a large amount of the geological, geophysical, petroleum exploration data and a large number of published research results, the basement constitutions and evolutions of tectonic-sedimentary of sedimentary basins, the main border fault belts and the orogenesis of their peripheries of the basins are analyzed. Especially, the main typical basins in the eight divisions in the continent of China are analyzed in detail, including the Tarim, Ordos, Sichuan, Songliao, Bohai Bay, Junggar, Qiadam and Qiangtang basins. The main five stages of superimposed evolutions processes of basins revealed, which accompanied with the tectonic processes of the Paleo-Asian Ocean, Tethyan and Western Pacific domains. They contained the formations of main Cratons (1850-800 Ma), developments of marine basins (800-386 Ma), developments of Marine- continental transition basins and super mantle plumes (386-252 Ma), amalgamation of China Continent and developments of continental basins (252-205 Ma) and development of the foreland basins in the western and extensional faulted basin in the eastern of China (205~0 Ma). Therefore, large scale marine sedimentary basins existed in the relatively stable continental blocks of the Proterozoic, developed during the Neoproterozoic to Paleozoic, with the property of the intracontinental cratons and peripheral foreland basins, the multistage superimposing and late reformations of basins. The continental basins developed on the weak or preexisting divisional basements, or the remnant and reformed marine basins in the Meso-Cenozoic, are mainly the continental margins, back-arc basins, retroarc foreland basins, intracontinental rifts and pull-apart basins. The styles and intensity deformation containing the faults, folds and the structural architecture of regional unconformities of the basins, responded to the openings, subductions, closures of oceans, the continent-continent collisions and reactivation of orogenies near the basins in different periods. The evolutions of the Tianshan-Mongol-Hinggan, Kunlun-Qilian-Qinling-Dabie-Sulu, Jiangshao-Shiwandashan, Helanshan-Longmengshan, Taihang-Wuling orogenic belts, the Tibet Plateau and the Altun and Tan- Lu Fault belts have importantly influenced on the tectonic-sedimentary developments, mineralization and hydrocarbon reservoir conditions of their adjacent basins in different times. The evolutions of basins also rely on the deep structures of lithosphere and the rheological properties of the mantle. The mosaic and mirroring geological structures of the deep lithosphere reflect the pre-existed divisions and hot mantle upwelling, constrain to the origins and transforms dynamics of the basins. The leading edges of the basin tectonic dynamics will focus on the basin and mountain coupling, reconstruction of the paleotectonic-paleogeography, establishing relationship between the structural deformations of shallow surface to the deep lithosphere or asthenosphere, as well as the restoring proto-basin and depicting residual basin of the Paleozoic basin, the effects of multiple stages of volcanism and paleo- earthquake events in China.展开更多
The dynamic soil-tunnel interaction is studied by the model of a rigid tunnel embedded in layered half-space, which is simplified as a single soil layer on elastic bedrock to the excitation of P- and SV-waves. The ind...The dynamic soil-tunnel interaction is studied by the model of a rigid tunnel embedded in layered half-space, which is simplified as a single soil layer on elastic bedrock to the excitation of P- and SV-waves. The indirect boundary element method is used, combined with the Green' s function of distributed loads acting on inclined lines. It is shown that the dynamic characteristics of soil-tunnel interaction in layered half-space are different much from that in homoge- neous half-space, and that the mechanism of soil-tunnel interaction is also different much from that of soil-founda- tion-superstructure interaction. For oblique incidence, the tunnel response for in-plane incident SV-waves is com- pletely different from that for incident SH-waves, while the tunnel response for vertically incident SV-wave is very similar to that of vertically incident SH-wave.展开更多
Interaction between beta-lactum antibiotic drug ciprofloxacin hydrochloride(CFH)and cationic surfactant cetyltrimethylammonium bromide(CTAB)was performed conductometrically in aqueous as well as in the occurrence of d...Interaction between beta-lactum antibiotic drug ciprofloxacin hydrochloride(CFH)and cationic surfactant cetyltrimethylammonium bromide(CTAB)was performed conductometrically in aqueous as well as in the occurrence of different salts(NaCl,KCl as well as NH_4Cl)over the temperature range of 298.15–323.15 K at the regular interval of 5 K.CFH drug has been suggested for the treatment of bacterial infections such as urinary tract infections and acute sinusitis.A clear critical micelle concentration(CMC)was obtained for pure CTAB as well as(CFH+CTAB)mixed systems.The decrease in CMC values of CTAB caused by the addition of CFH reveals the existence of the interaction between the components and therefore it is the indication of micelle formation at lower concentration of CTAB and their CMC values further decrease in attendance of salts.A nonlinear behavior in the CMC versus T plot was observed in all the cases.The ΔG_m^0 values are found to be negative in present study systems demonstrated the stability of the solution.The values of ΔH_m^0 and ΔS_m^0 reveal the existence of hydrophobic and electrostatic interactions between CFH and CTAB.The thermodynamic properties of transfer for the micellization were also evaluated and discussed in detail.Molecular dynamic simulation disclosed that environment of water and salts have impact on the hydrophobic interaction between CFH and CTAB.In water and salts,CTAB adopts spherical micelle in which charged hydrophilic groups are interacted with waters whereas hydrophobic tails form the core of the micelle.This hydrophobic core region is highly conserved and protected.In addition,micelle formation is more favorable in aqueous Na Cl solution than other solutions.展开更多
基金supported by the Consortium for Advanced Research Training in Africa(CARTA)CARTA is jointly led by the African Population and Health Research Center and the University of the Witwatersrand and funded by the Wellcome Trust(UK)(Grant No:087547/Z/08/Z)+5 种基金the Department for International Development(DfID)under the Development Partnerships in Higher Education(DelPHE)the Carnegie Corporation of New York(Grant No:B 8606)the Ford Foundation(Grant No:1100-0399)Google.Org(Grant No:191994)Sida(Grant No:54100029)MacArthur Foundation Grant No:10-95915-000-INP.
文摘Background:Despite increasing recognition that health-systems constraints are the fundamental barrier to attaining anti-retroviral therapy(ART)scale-up targets in Sub-Saharan Africa,current discourses are dominated by a focus on financial sustainability.Utilizing the health system dynamics framework,this study aimed to explore the interactions in health system components and their influence on the sustainability of ART scale-up implementation in Uganda.Methods:This study entailed qualitative organizational case-studies within a two-phased mixed-methods sequential explanatory research design.In Phase One,a survey of 195 health facilities across Uganda which commenced ART services between 2004 and 2009 was conducted.In Phase Two,six health facilities were purposively selected for in-depth examination involving i)In-depth interviews(n=44)ii)and semistructured interviews(n=35).Qualitative data was analyzed by coding and thematic analysis.Descriptive statistics were managed in STATA(v 13).Results:Five dynamic interactions in ART program sustainability drivers were identified;i)Failure to update basic ART program records contributed to chronic ART medicines stock-outs ii)Health workforce shortages and escalating patient volumes prompted adaptations in ART service delivery models iii)Broader governance issues manifested in poor road networks undermined ART medicines supply chains iv)Sustained financing for ART programs was influenced by external donors v)The values associated with the ownership-type of a health facility affected ART service delivery and coverage.Conclusion:The sustainability of ART programs at the facility-level in Uganda is a function of a complex interaction in elements of the health system and must be understood beyond sustaining international funding for ART scale-up.
基金supported by the National Natural Science Foundation of China (No. 50975238)
文摘Improving freight axle load is the most effective method to improve railway freight capability; based on the imported technologies of railway freight bogie, the 27 t axle load side-frame cross-bracing bogie and sub-frame radial bogie are developed in China. In order to analyze and compare dynamic interactions of the two newly developed heavy-haul freight bogies, we establish a vehi- cle-track coupling dynamic model and use numerical calculation methods for computer simulation. The dynamic performances of the two bogies are simulated separately at various conditions. The results show that at the dipped joint and straight line running conditions, the wheel-rail dynamic interactions of both bogies are basically the same, but at the curve negotiation condition, the wear and the lateral force of the side-frame cross-bracing bogie are much higher than that of the sub-frame radial bogie, and the advantages become more obvious when the curve radius is smaller. The results also indicate that the sub- frame radial bogie has better low-wheel-rail interaction characteristics.
基金supported by European Union’s Horizon 2020 research and innovation programme in the project In2Track2 under Grant agreement No. 826255
文摘By modifying friction to the desired level,the application of friction modifiers(FMs)has been considered as a promising emerging tool in the railway engineering for increasing braking/traction force in poor adhesion conditions and mitigating wheel/rail interface deterioration,energy consumption,vibration and noise.Understanding the effectiveness of FMs in wheel–rail dynamic interactions is crucial to their proper applications in practice,which has,however,not been well explained.This study experimentally investigates the effects of two types of top-of-rail FM,i.e.FM-A and FM-B,and their application dosages on wheel–rail dynamic interactions with a range of angles of attack(AoAs)using an innovative well-controlled V-track test rig.The tested FMs have been used to provide intermediate friction for wear and noise reduction.The effectiveness of the FMs is assessed in terms of the wheel–rail adhesion characteristics and friction rolling induced axle box acceleration(ABA).This study provides the following new insights into the study of FM:the applications of the tested FMs can both reduce the wheel–rail adhesion level and change the negative friction characteristic to positive;stick–slip can be generated in the V-Track and eliminated by FM-A but intensified by FM-B,depending on the dosage of the FMs applied;the negative friction characteristic is not a must for stick–slip;the increase in ABA with AoA is insignificant until stick–slip occurs and the ABA can thus be influenced by the applications of FM.
文摘Maintaining the integrity and longevity of structures is essential in many industries,such as aerospace,nuclear,and petroleum.To achieve the cost-effectiveness of large-scale systems in petroleum drilling,a strong emphasis on structural durability and monitoring is required.This study focuses on the mechanical vibrations that occur in rotary drilling systems,which have a substantial impact on the structural integrity of drilling equipment.The study specifically investigates axial,torsional,and lateral vibrations,which might lead to negative consequences such as bit-bounce,chaotic whirling,and high-frequency stick-slip.These events not only hinder the efficiency of drilling but also lead to exhaustion and harm to the system’s components since they are difficult to be detected and controlled in real time.The study investigates the dynamic interactions of these vibrations,specifically in their high-frequency modes,usingfield data obtained from measurement while drilling.Thefindings have demonstrated the effect of strong coupling between the high-frequency modes of these vibrations on drilling sys-tem performance.The obtained results highlight the importance of considering the interconnected impacts of these vibrations when designing and implementing robust control systems.Therefore,integrating these compo-nents can increase the durability of drill bits and drill strings,as well as improve the ability to monitor and detect damage.Moreover,by exploiting thesefindings,the assessment of structural resilience in rotary drilling systems can be enhanced.Furthermore,the study demonstrates the capacity of structural health monitoring to improve the quality,dependability,and efficiency of rotary drilling systems in the petroleum industry.
基金Project(10872219) supported by the National Natural Science Foundation of China
文摘The finite element method was used to solve fluid dynamic interaction problems between the crust and mantle of the Earth. To consider different mechanical behaviours, the lithosphere consisting of the crust and upper mantle was simulated as fluid-saturated porous rocks, while the upper aesthenospheric part of the mantle was simulated as viscous fluids. Since the whole lithosphere was computationally simulated, the dynamic interaction between the crust and the upper mantle was appropriately considered. In particular, the mixing of mantle fluids and crustal fluids was simulated in the corresponding computational model. The related computational simulation results from an example problem demonstrate that the mantle fluids can flow into the crust and mix with the crustal fluids due to the resulting convective flows in the crust-mantle system. Likewise, the crustal fluids can also flow into the upper mantle and mix with the mantle fluids. This kind of fluids mixing and exchange is very important to the better understanding of the governing processes that control the ore body formation and mineralization in the upper crust of the Earth.
文摘This paper analyses the modal interactions in the nonlinear, size-dependent dynamics of geometrically imperfect microplates. Based on the modified couple stress theory,the equations of motion for the in-plane and out-of-plane motions are obtained employing the von Kármán plate theory as well as Kirchhoff's hypotheses by means of the Lagrange equations. The equations of motions are solved using the pseudo-arclength continuation technique and direct timeintegration method. The system parameters are tuned to the values associated with modal interactions, and then nonlinear resonant responses and energy transfer are analysed.Nonlinear motion characteristics are shown in the form of frequency-response and force-response curves, time histories, phase-plane portraits, and fast Fourier transforms.
文摘Using the mean-field theory and Glauber-type stochastic dynamics, we study the dynamic magnetic properties of the mixed spin (2, 5/2) Ising system for the antiferromagnetic/antiferromagnetic (AFM/AFM) interactions on the bilayer square lattice under a time varying (sinusoidal) magnetic field. The time dependence of average magnetizations and the thermal variation of the dynamic magnetizations are examined to calculate the dynamic phase diagrams. The dynamic phase diagrams are presented in the reduced temperature and magnetic field amplitude plane and the effects of interlayer coupling interaction on the critical behavior of the system are investigated. We also investigate the influence of the frequency and find that the system displays richer dynamic critical behavior for higher values of frequency than that of the lower values of it. We perform a comparison with the ferromagnetic/ferromagnetic (FM/FM) and AFM/FM interactions in order to see the effects of AFM/AFM interaction and observe that the system displays richer and more interesting dynamic critical behaviors for the AFM/AFM interaction than those for the FM/FM and AFM/FM interactions.
基金Supported by the National Natural Science Foundation of China under Grant No 11674146the National Basic Research Program of China under Grant No 2013CBA01500
文摘Generation of attosecond electromagnetic (EM) pulses and the associated electron dynamics are studied using particle-in-cell simulations of relativistic laser pulses interacting with over-dense plasma foil targets. The inter- action process is found to be so complicated even in the situation of utilizing driving laser pulses of only one cycle. Two electron bunches closely involved in the laser-driven wavebreaking process contribute to attosecond EM pulses through the coherent synchrotron emission process whose spectra are found to follow an exponential decay rule. Detailed investigations of electron dynamics indicate that the early part of the reflected EM emission is the high-harmonics produced through the relativistic oscillating mirror mechanism. High harmonics are also found to be generated through the Bremsstrahlung radiation by one electron bunch that participates in the wavebreaking process and decelerates when it experiences the local wavebreaking-generated high electrostatic field in the moving direction.
基金Acknowledgements This research is sponsored by the Major State Basic Research Development Program of China ("973" Program) (2013CB036203), the 111 Project (B13002), and the National Natural Science Foundation of China (U1434205, U1434210, 51338001 ).
文摘The train-bridge dynamic interaction problem began with the development of railway technology, and requires an evaluation method for bridge design in order to ensure the safety and stability of the bridge and the running train. This problem is studied using theoretical analysis, numerical simulation, and experimental study. In the train-bridge dynamic interaction system proposed in this paper, the train vehicle model is established by the rigid-body dynamics method, the bridge model is established by the finite element method, and the wheel/rail vertical and lateral interaction are simulated by the corresponding assumption and the Kalker linear creep theory, respectively. Track irregularity, structure deformation, wind load, collision load, structural damage, foundation scouring, and earthquake action are regarded as the excitation for the system. The train-bridge dynamic interaction system is solved by inter-history iteration. A case study of the dynamic response of a CRH380BL high-speed train running through a standard-design bridge in China is discussed. The dynamic responses of the vehicle and of the bridge subsystems are obtained for speeds ranging from 200 km-b-1 to 400 km.h-1, and the vibration mechanism are analyzed.
基金Project(50879077) supported by the National Natural Science Foundation of China
文摘Taking the effect of finite soil layers below pile end into account,the longitudinal dynamic response of pile undergoing dynamic loading in layered soil was theoretically investigated.Firstly,finite soil layers below pile end are modeled as virtual soil pile whose cross-section area is the same as that of the pile and the soil layers surrounding the pile are described by the plane strain model.Then,by virtue of Laplace transform and impedance function transfer method,the analytical solution of longitudinal dynamic response at the pile head in frequency domain is yielded.Also,the semi-analytical solution in time domain undergoing half-cycle sine pulse at the pile head is obtained by means of inverse Laplace transform.Based on these solutions,a parametric study is conducted to analyze emphatically the effects of parameters of soil below pile end on velocity admittance and reflected wave signals at the pile head.Additionally,a comparison with other models with different supporting conditions from soil below pile end is performed to verify the model presented.
基金supported by the Funds for Creative Research Groups of China(51021001)the National Natural Science Foundation of China(51078351)Program for New Century Excellent Talents in University,Fund of Key Laboratory of Bridge-structure Engineering and Open Fund of Key Laboratory of Road & Bridge and Underground Engineering of Gansu Province(KFJJ-11-03)
文摘Due to the wide applications of arches in underground protective structures, dynamic analysis of circular arches including soil-structure interactions is important. In this paper, an exact solution of the forced vibration of circular arches subjected to subsurface denotation forces is obtained. The dynamic soil-structure interaction is considered with the introduction of an interfacial damping between the structure element and the surrounding soil into the equa- tion of motion. By neglecting the influences of shear, rotary inertia and tangential forces and assuming the arch incompressible, the equations of motion of the buried arches were set up. Analytical solutions of the dynamic responses of the protective arches were deduced by means of modal super- position. Arches with different opening angles, acoustic impedances and rise-span ratios were analyzed to discuss their influences on an arch. The theoretical analysis suggests blast loads for elastic designs and predicts the potential failure modes for buried protective arches.
文摘BACKGROUND Nursing practices based on the dynamic interaction model have been shown to be superior to generic nursing practices.However,whether this model is effective in patients recovering from intracranial aneurysm surgery is not well studied.AIM To investigate the effect of nursing based on a dynamic interaction model on functional rehabilitation of patients after aneurysm surgery.METHODS A total of 86 cases in our hospital with intracranial aneurysm from April 2019 to April 2021,were selected and divided into the study group and the control group,with 43 patients in each group.The control group received routine nursing,and the research group received nursing intervention based on a dynamic interaction model.The daily living ability(activities of daily living,ADL),cognitive function(Simple Intelligent Mental State Scale,MMSE),quality of life(Generic Quality of Life Inventory-74,GQOL-74),self-care ability(Exercise of Self-Care Agency scale),incidence of complications,and nursing satisfaction were recorded before and after intervention.RESULTS Before intervention,ADL(52.09±6.44),MMSE(18.03±4.11),and GQOL-74(53.68±4.34)scores in the study group were not significantly different from those in the control group(ADL:50.97±7.32,MMSE:17.59±3.82,GQOL-74:55.06±3.98)(P>0.05).After intervention,ADL(86.12±5.07),MMSE(26.64±2.66),and GQOL-74(83.13±5.67)scores in the study group were higher than those in the control group(ADL:79.81±6.35,MMSE:24.51±3.00,and GQOL-74:77.96±6.27)(P<0.05).Before intervention,self-concept(17.46±4.44),self-care skills(25.22±4.20),self-care knowledge(22.35±4.74),and self-care responsibility(15.06±3.29)scores in the study group was similar to those in the control group(self-concept:16.89±5.53,self-care skills:24.59±4.46,self-care knowledge:21.80±3.61,and self-care responsibility:14.83±3.11)(P>0.05).After the intervention,self-concept(26.01±3.18),self-care skills(37.68±6.05),self-care knowledge(45.56±5.83),and self-care responsibility(22.01±3.77)scores in the study group were higher than those in the control group(self-concept:22.97±3.46,self-care skills:33.02±5.65,selfcare skills knowledge:36.81±5.54,and self-care responsibility:17.97±3.56 points)(P<0.05).The incidence of complications in the study group(4.65%)was lower than that in the control group(18.60%)(P<0.05).Nursing satisfaction in the study group(95.35%)was higher than that in the control group(81.40%)(P<0.05).CONCLUSION Nursing intervention based on a dynamic interaction model can improve postoperative cognitive function,daily living ability,self-care ability,quality of life,and patient satisfaction,while reducing the risk of complications.
基金supported by the Tianjin Research Program of Application Foundation Advanced Technology (14JCYBJC21900)the National Natural Science Foundation of China under grants 51278327
文摘The scattering of plane harmonic P and SV waves by a pair of vertically overlapping lined tunnels buried in an elastic half space is solved using a semi-analytic indirect boundary integration equation method. Then the effect of the distance between the two tunnels, the stiffness and density of the lining material, and the incident frequency on the seismic response of the tunnels is investigated. Numerical results demonstrate that the dynamic interaction between the twin tunnels cannot be ignored and the lower tunnel has a significant shielding effect on the upper tunnel for high-frequency incident waves, resulting in great decrease of the dynamic hoop stress in the upper tunnel; for the low-frequency incident waves, in contrast, the lower tunnel can lead to amplification effect on the upper tunnel. It also reveals that the frequency-spectrum characteristics of dynamic stress of the lower tunnel are significantly different from those of the upper tunnel. In addition, for incident P waves in low-frequency region, the soft lining tunnels have significant amplification effect on the surface displacement amplitude, which is slightly larger than that of the corresponding single tunnel.
基金the State Key Program of National Natural Science of China under Grant No.51138001Science Fund for Creative Research Groups of the National Natural Science Foundation of China under Grant No.51121005Open Research Fund Program of State key Laboratory of Hydro science and Engineering under Grant No.shlhse-2010-C-03
文摘Consideration of structure-foundation-soil dynamic interaction is a basic requirement in the evaluation of the seismic safety of nuclear power facilities. An efficient and accurate dynamic interaction numerical model in the time domain has become an important topic of current research. In this study, the scaled boundary finite element method (SBFEM) is improved for use as an effective numerical approach with good application prospects. This method has several advantages, including dimensionality reduction, accuracy of the radial analytical solution, and unlike other boundary element methods, it does not require a fundamental solution. This study focuses on establishing a high performance scaled boundary finite element interaction analysis model in the time domain based on the acceleration unit-impulse response matrix, in which several new solution techniques, such as a dimensionless method to solve the interaction force, are applied to improve the numerical stability of the actual soil parameters and reduce the amount of calculation. Finally, the feasibility of the time domain methods are illustrated by the response of the nuclear power structure and the accuracy of the algorithms are dynamically verified by comparison with the refinement of a large-scale viscoelastic soil model.
基金This work was supported by the National Natural Science Foundation of China(Grant Nos.52008404,U1934217 and 11790283)Science and Technology Research and Development Program Project of China Railway Group Limited(Major Special Project,No.2020-Special-02)the National Natural Science Foundation of Hunan Province(Grant No.2021JJ30850).
文摘In this work,a method is put forward to obtain the dynamic solution efficiently and accurately for a large-scale train-track-substructure(TTS)system.It is called implicit-explicit integration and multi-time-step solution method(abbreviated as mI-nE-MTS method).The TTS system is divided into train-track subsystem and substruc-ture subsystem.Considering that the root cause of low effi-ciency of obtaining TTS solution lies in solving the alge-braic equation of the substructures,the high-efficient Zhai method,an explicit integration scheme,can be introduced to avoid matrix inversion process.The train-track system is solved by implicitly Park method.Moreover,it is known that the requirement of time step size differs for different sub-systems,integration methods and structural frequency response characteristics.A multi-time-step solution is pro-posed,in which time step size for the train-track subsystem and the substructure subsystem can be arbitrarily chosen once satisfying stability and precision demand,namely the time spent for m implicit integral steps is equal to n explicit integral steps,i.e.,mI=nE as mentioned above.The numeri-cal examples show the accuracy,efficiency,and engineering practicality of the proposed method.
基金support of JASSO to conduct this research work during the author’s stay at Japan
文摘Nowadays,there are many studies conducted in the field of marine hydrodynamics which focus on two vessels traveling and floating in sufficiently close proximity to experience significant interactions.The hydrodynamic behavior of parallel moving ships in waves is an interesting and important topic of late.A numerical investigation has been carried out for the prediction of wave exciting forces and motion responses of parallel moving ships in regular waves.The numerical solution was based on 3D distribution technique and using the linear wave theory to determine the exciting forces and ship's motion.The speed effects have been considered in the Green function for more realistic results.The numerical computations of wave exciting forces and motion responses were carried out for a Mariner and Series 60 for the purpose of discovering different Froude numbers and different separation distances in head sea conditions.Based on the numerical computations,it was revealed that the sway,roll and yaw have a significant effect due to hydrodynamic interaction.
基金This work was supported by the National Natural Science Foundation of China(Grant No.52008404)the National Natural Science Foundation of Hunan Province(Grant No.2021JJ30850).
文摘Train–track–substructure dynamic interaction is an extension of the vehicle–track coupled dynamics.It contributes to evaluate dynamic interaction and performance between train–track system and its substructures.For the first time,this work devotes to presenting engineering practical methods for modeling and solving such large-scale train–track–substructure interaction systems from a unified viewpoint.In this study,a train consists of several multi-rigid-body vehicles,and the track is modeled by various finite elements.The track length needs only satisfy the length of a train plus boundary length at two sides,despite how long the train moves on the track.The substructures and their interaction matrices to the upper track are established as independent modules,with no need for additionally building the track structures above substructures,and accordingly saving computational cost.Track–substructure local coordinates are defined to assist the confirming of the overlapped portions between the train–track system and the substructural system to effectively combine the cyclic calculation and iterative solution procedures.The advancement of this model lies in its convenience,efficiency and accuracy in continuously considering the vibration participation of multi-types of substructures against the moving of a train on the track.Numerical examples have shown the effectiveness of this method;besides,influence of substructures on train–track dynamic behaviors is illustrated accompanied by clarifying excitation difference of different track irregularity spectrums.
基金supported by the work project of China Geological Survey(No.12120115002001-4,12120115026901)the Science Research from the Northwest Oilfield Sub–company of SINOPEC(No:KY2013–S–024)+1 种基金a Special Research Grant from Ministry of Land and Resources of the People’s Republic of China(No.201011034)the Innovation Group of National Natural Science Foundation of China(No.40921001)
文摘The formation and evolution of basins in the China continent are closely related to the collages of many blocks and orogenic belts. Based on a large amount of the geological, geophysical, petroleum exploration data and a large number of published research results, the basement constitutions and evolutions of tectonic-sedimentary of sedimentary basins, the main border fault belts and the orogenesis of their peripheries of the basins are analyzed. Especially, the main typical basins in the eight divisions in the continent of China are analyzed in detail, including the Tarim, Ordos, Sichuan, Songliao, Bohai Bay, Junggar, Qiadam and Qiangtang basins. The main five stages of superimposed evolutions processes of basins revealed, which accompanied with the tectonic processes of the Paleo-Asian Ocean, Tethyan and Western Pacific domains. They contained the formations of main Cratons (1850-800 Ma), developments of marine basins (800-386 Ma), developments of Marine- continental transition basins and super mantle plumes (386-252 Ma), amalgamation of China Continent and developments of continental basins (252-205 Ma) and development of the foreland basins in the western and extensional faulted basin in the eastern of China (205~0 Ma). Therefore, large scale marine sedimentary basins existed in the relatively stable continental blocks of the Proterozoic, developed during the Neoproterozoic to Paleozoic, with the property of the intracontinental cratons and peripheral foreland basins, the multistage superimposing and late reformations of basins. The continental basins developed on the weak or preexisting divisional basements, or the remnant and reformed marine basins in the Meso-Cenozoic, are mainly the continental margins, back-arc basins, retroarc foreland basins, intracontinental rifts and pull-apart basins. The styles and intensity deformation containing the faults, folds and the structural architecture of regional unconformities of the basins, responded to the openings, subductions, closures of oceans, the continent-continent collisions and reactivation of orogenies near the basins in different periods. The evolutions of the Tianshan-Mongol-Hinggan, Kunlun-Qilian-Qinling-Dabie-Sulu, Jiangshao-Shiwandashan, Helanshan-Longmengshan, Taihang-Wuling orogenic belts, the Tibet Plateau and the Altun and Tan- Lu Fault belts have importantly influenced on the tectonic-sedimentary developments, mineralization and hydrocarbon reservoir conditions of their adjacent basins in different times. The evolutions of basins also rely on the deep structures of lithosphere and the rheological properties of the mantle. The mosaic and mirroring geological structures of the deep lithosphere reflect the pre-existed divisions and hot mantle upwelling, constrain to the origins and transforms dynamics of the basins. The leading edges of the basin tectonic dynamics will focus on the basin and mountain coupling, reconstruction of the paleotectonic-paleogeography, establishing relationship between the structural deformations of shallow surface to the deep lithosphere or asthenosphere, as well as the restoring proto-basin and depicting residual basin of the Paleozoic basin, the effects of multiple stages of volcanism and paleo- earthquake events in China.
基金supported by the National Natural Science Foundation of China(No.51378384)the Key Project of Natural Science Foundation of Tianjin Municipality(No. 12JCZDJC29000)
文摘The dynamic soil-tunnel interaction is studied by the model of a rigid tunnel embedded in layered half-space, which is simplified as a single soil layer on elastic bedrock to the excitation of P- and SV-waves. The indirect boundary element method is used, combined with the Green' s function of distributed loads acting on inclined lines. It is shown that the dynamic characteristics of soil-tunnel interaction in layered half-space are different much from that in homoge- neous half-space, and that the mechanism of soil-tunnel interaction is also different much from that of soil-founda- tion-superstructure interaction. For oblique incidence, the tunnel response for in-plane incident SV-waves is com- pletely different from that for incident SH-waves, while the tunnel response for vertically incident SV-wave is very similar to that of vertically incident SH-wave.
文摘Interaction between beta-lactum antibiotic drug ciprofloxacin hydrochloride(CFH)and cationic surfactant cetyltrimethylammonium bromide(CTAB)was performed conductometrically in aqueous as well as in the occurrence of different salts(NaCl,KCl as well as NH_4Cl)over the temperature range of 298.15–323.15 K at the regular interval of 5 K.CFH drug has been suggested for the treatment of bacterial infections such as urinary tract infections and acute sinusitis.A clear critical micelle concentration(CMC)was obtained for pure CTAB as well as(CFH+CTAB)mixed systems.The decrease in CMC values of CTAB caused by the addition of CFH reveals the existence of the interaction between the components and therefore it is the indication of micelle formation at lower concentration of CTAB and their CMC values further decrease in attendance of salts.A nonlinear behavior in the CMC versus T plot was observed in all the cases.The ΔG_m^0 values are found to be negative in present study systems demonstrated the stability of the solution.The values of ΔH_m^0 and ΔS_m^0 reveal the existence of hydrophobic and electrostatic interactions between CFH and CTAB.The thermodynamic properties of transfer for the micellization were also evaluated and discussed in detail.Molecular dynamic simulation disclosed that environment of water and salts have impact on the hydrophobic interaction between CFH and CTAB.In water and salts,CTAB adopts spherical micelle in which charged hydrophilic groups are interacted with waters whereas hydrophobic tails form the core of the micelle.This hydrophobic core region is highly conserved and protected.In addition,micelle formation is more favorable in aqueous Na Cl solution than other solutions.