The short secret key characteristic of elliptic curve cryptosystem (ECC) are integrated with the ( t, n ) threshold method to create a practical threshold group signature scheme characterized by simultaneous signi...The short secret key characteristic of elliptic curve cryptosystem (ECC) are integrated with the ( t, n ) threshold method to create a practical threshold group signature scheme characterized by simultaneous signing. The scheme not only meets the requirements of anonymity and traceability of group signature but also can withstand Tseng and Wang's conspiracy attack. It allows the group manager to add new members and delete old members according to actual application, while the system parameters have a little change. Cryptanalysis result shows that the scheme is efficient and secure.展开更多
In this paper, a new dynamic group signature scheme is proposed. It allows the group manager to increase or delete group members flexibly. Furthermore, the length of group signatures, as well as the computational effo...In this paper, a new dynamic group signature scheme is proposed. It allows the group manager to increase or delete group members flexibly. Furthermore, the length of group signatures, as well as the computational effort for signing, verifying and opening are very small and independent of the number of group members and deleted group members. So it is efficient.展开更多
DNA methylation is a critical epigenetic regulator in the occurrence and development of diseases and is closely related to various functional responses in relation to spinal cord injury.To investigate the role of DNA ...DNA methylation is a critical epigenetic regulator in the occurrence and development of diseases and is closely related to various functional responses in relation to spinal cord injury.To investigate the role of DNA methylation in spinal cord injury,we constructed a library with reduced-representation bisulfite sequencing data obtained at various time points(day 0-42)after spinal cord injury in mice.Global DNA methylation levels,specifically non-CpG(CHG and CHH)methylation levels,decreased modestly following spinal cord injury.Stages post-spinal cord injury were classified as early(day 0-3),intermediate(day7-14),and late(day 28-42)based on similarity and hie rarchical cluste ring of global DNA methylation patterns.The non-CpG methylation level,which included CHG and CHH methylation levels,was markedly reduced despite accounting for a minor proportion of total methylation abundance.At multiple genomic sites,including the 5’untranslated regions,promoter,exon,intron,and 3’untranslated regions,the non-CpG methylation level was markedly decreased following spinal cord injury,whereas the CpG methylation level remained unchanged at these locations.Approximately one-half of the differentially methylated regions were located in intergenic areas;the other differentially methylated regions in both CpG and non-CpG regions were cluste red in intron regions,where the DNA methylation level was highest.The function of genes associated with differentially methylated regions in promoter regions was also investigated.From Gene Ontology analysis results,DNA methylation was implicated in a number of essential functional responses to spinal cord injury,including neuronal synaptic connection creation and axon regeneration.Notably,neither CpG methylation nor non-CpG methylation was implicated in the functional response of glial or inflammatory cells.In summary,our work elucidated the dynamic pattern of DNA methylation in the spinal co rd following injury and identified reduced nonCpG methylation as an epigenetic target after spinal cord injury in mice.展开更多
A forward-secure group signature(FSGS)ensures the unforgeability of signatures in the past time period despite signing secret key is leaked in the current time period.As we know,traditional FSGS schemes are mostly rel...A forward-secure group signature(FSGS)ensures the unforgeability of signatures in the past time period despite signing secret key is leaked in the current time period.As we know,traditional FSGS schemes are mostly relying on number-theoretic assumptions unable to resist quantum attacks.Therefore,we present an efficient lattice-based fully dynamic(ie.users can flexibly join or quit the group)forward-secure group signature(DFSGS)by combining an improved version of FSGS scheme proposed by Ling.Based on an efficient zero-knowledge argument,we construct argument of knowledge of the committed value and the plaintext that help with privacy protection.Our DFSGS scheme is proved to be anonymous and forward-secure traceable relying on short integer solution and learning with errors assumptions in random oracle model.Moreover,the lengths of group public key and signature of our DFSGS scheme have been improved,and the length of user secret key has no connection with the quantity of group members.展开更多
Message-dependent opening is one of the solutions to solve the problem of the tracing manager owns excessive power.In this paper,we present a new lattice-based fully dynamic group signature scheme with message-depende...Message-dependent opening is one of the solutions to solve the problem of the tracing manager owns excessive power.In this paper,we present a new lattice-based fully dynamic group signature scheme with message-dependent opening by combining an improved version of the fully dynamic group signature scheme proposed by Ling et al and the double encryption paradigm.In addition,we propose an improved underlying zero knowledge protocol,it has a soundness error 1 max(n,p)+1 that is better than the Stern-like protocol,which helps to bring down the communication complexity of the protocol and hence the signature scheme.Our scheme constrains the power of group managers by adding an admitter,and the signature size has a logarithmic relationship with the group size.展开更多
基金The National Natural Science Foundation of China (No60403027)
文摘The short secret key characteristic of elliptic curve cryptosystem (ECC) are integrated with the ( t, n ) threshold method to create a practical threshold group signature scheme characterized by simultaneous signing. The scheme not only meets the requirements of anonymity and traceability of group signature but also can withstand Tseng and Wang's conspiracy attack. It allows the group manager to add new members and delete old members according to actual application, while the system parameters have a little change. Cryptanalysis result shows that the scheme is efficient and secure.
基金Supported by the Scientific Research Plan Projectof the Education Department of Shaanxi Province (06JK197)
文摘In this paper, a new dynamic group signature scheme is proposed. It allows the group manager to increase or delete group members flexibly. Furthermore, the length of group signatures, as well as the computational effort for signing, verifying and opening are very small and independent of the number of group members and deleted group members. So it is efficient.
基金National Key Research and Development Program of China,No.2016YFA0100800(to LC)International(Regional)Cooperation and Communication Program of the National Natural Science Foundation of China,No.81820108013(to LC)+3 种基金State Key Program of the National Natural Science Foundation of China,No.81330030(to LC)National Natural Science Foundation of China,Nos.82071370(to ZW),81301042(to LC)Shanghai Pujiang Program,No.19PJ1409200(to ZW)Shanghai Sailing Program,No.21YF1442400(to CL)。
文摘DNA methylation is a critical epigenetic regulator in the occurrence and development of diseases and is closely related to various functional responses in relation to spinal cord injury.To investigate the role of DNA methylation in spinal cord injury,we constructed a library with reduced-representation bisulfite sequencing data obtained at various time points(day 0-42)after spinal cord injury in mice.Global DNA methylation levels,specifically non-CpG(CHG and CHH)methylation levels,decreased modestly following spinal cord injury.Stages post-spinal cord injury were classified as early(day 0-3),intermediate(day7-14),and late(day 28-42)based on similarity and hie rarchical cluste ring of global DNA methylation patterns.The non-CpG methylation level,which included CHG and CHH methylation levels,was markedly reduced despite accounting for a minor proportion of total methylation abundance.At multiple genomic sites,including the 5’untranslated regions,promoter,exon,intron,and 3’untranslated regions,the non-CpG methylation level was markedly decreased following spinal cord injury,whereas the CpG methylation level remained unchanged at these locations.Approximately one-half of the differentially methylated regions were located in intergenic areas;the other differentially methylated regions in both CpG and non-CpG regions were cluste red in intron regions,where the DNA methylation level was highest.The function of genes associated with differentially methylated regions in promoter regions was also investigated.From Gene Ontology analysis results,DNA methylation was implicated in a number of essential functional responses to spinal cord injury,including neuronal synaptic connection creation and axon regeneration.Notably,neither CpG methylation nor non-CpG methylation was implicated in the functional response of glial or inflammatory cells.In summary,our work elucidated the dynamic pattern of DNA methylation in the spinal co rd following injury and identified reduced nonCpG methylation as an epigenetic target after spinal cord injury in mice.
基金This work is supported by the Major Program of Guangdong Basic and Applied Research(2019B030302008)National Natural Science Foundation of China(61872152)Science and Technology Program of Guangzhou(201902010081)。
文摘A forward-secure group signature(FSGS)ensures the unforgeability of signatures in the past time period despite signing secret key is leaked in the current time period.As we know,traditional FSGS schemes are mostly relying on number-theoretic assumptions unable to resist quantum attacks.Therefore,we present an efficient lattice-based fully dynamic(ie.users can flexibly join or quit the group)forward-secure group signature(DFSGS)by combining an improved version of FSGS scheme proposed by Ling.Based on an efficient zero-knowledge argument,we construct argument of knowledge of the committed value and the plaintext that help with privacy protection.Our DFSGS scheme is proved to be anonymous and forward-secure traceable relying on short integer solution and learning with errors assumptions in random oracle model.Moreover,the lengths of group public key and signature of our DFSGS scheme have been improved,and the length of user secret key has no connection with the quantity of group members.
基金the National Natural Science Foundation of China(Grant No.61932019,No.61772521,No.61772522)the Key Research Program of Frontier Sciences,CAS(Grant No.QYZDB-SSW-SYS035).
文摘Message-dependent opening is one of the solutions to solve the problem of the tracing manager owns excessive power.In this paper,we present a new lattice-based fully dynamic group signature scheme with message-dependent opening by combining an improved version of the fully dynamic group signature scheme proposed by Ling et al and the double encryption paradigm.In addition,we propose an improved underlying zero knowledge protocol,it has a soundness error 1 max(n,p)+1 that is better than the Stern-like protocol,which helps to bring down the communication complexity of the protocol and hence the signature scheme.Our scheme constrains the power of group managers by adding an admitter,and the signature size has a logarithmic relationship with the group size.