The place and placeness are believed to be a crucial perspective for comprehending the transformative dynamics of tourist destinations in the context of globalization and the rapid development of the tourism industry....The place and placeness are believed to be a crucial perspective for comprehending the transformative dynamics of tourist destinations in the context of globalization and the rapid development of the tourism industry.As the material carrier of language,linguistic landscape is an intermediary for people to endow emotions and personalities into the place,becoming an effective path for exploring the place-making in a certain area.Mogan Mountain is a famous national tourist resort,which is located in Mogan Mountain Town,Deqing County,Huzhou City,China.This is a good case area for studying the relationship between linguistic landscape and placemaking in tourist destinations.There are two theories that form the theoretical foundation of the study,namely the place and the geosemiotics.Firstly,the results showed the overall style of the linguistic landscape.Multilingual labelling(52.7%),official signs(55.3%),and standardized Chinese characters predominantly shaped the linguistic landscape,with English and other languages being complementary.Secondly,from the perspective of three dimensions of the geosemiotics framework,such as inscription,language preference,and placement position,we conduct a comprehensive semiotic analysis of the linguistic landscape,which encompasses diverse facets such as fonts,materials,shifts in state,text vectors,and symmetrical arrangements.Finally,we explore the influence of linguistic landscapes on the place-making of Mogan Mountain through the dimensions of location,locale,and sense of place.The information on linguistic landscapes indicates the geographical location.These linguistic landscapes play an important role in constructing the language order,nostalgic atmosphere,exotic atmosphere,and elegant and tasteful lifestyle of the public space in Mogan Mountain.Readers of linguistic landscapes,including tourists and residents,generate and identify with the unique sense of place in Mogan Mountain.These linguistic landscapes construct the destination placeness of Mogan Mountain that combines both foreign and nostalgic styles,and the integration of Chinese and Western cultures.It will help promote the image positioning of tourism destinations and have practical guiding significance for the tourism planning,landscape-making,language management,and other aspects of tourism destinations.展开更多
In the novel“A Clean,Well-lighted Place”,Hemingway tells the story of two waiters in a Spanish caféjust before closing time,talking about an old man who drank heavily in the caféevery night and lived a wea...In the novel“A Clean,Well-lighted Place”,Hemingway tells the story of two waiters in a Spanish caféjust before closing time,talking about an old man who drank heavily in the caféevery night and lived a wealthy life but still wants to commit suicide.Using the iceberg principle,Hemingway purposely omits the plot,characterization of the story,and uses symbolism and repetition to describe people’s different attitudes facing the spiritual emptiness after the war,breaking the readers’expectations,and inspiring them to explore the meaning of individual life.Therefore,based on Wolfgang Iser and Zhu Liyuan’s appealing structure theory,this paper will analyze the appealing structure in“A Clean,Well-lighted Place”at three levels:meaning construction,rhetorical techniques,and thoughts and themes.It is hoped that readers can find a new way to interpret the short story,better understand the author’s creative ideas and dig deeper into the connotation of the work.展开更多
As leading figures in English literature during the Neoclassical period,Alexander Pope and Jonathan Swift both showed great concern with the nature of man and his place in the Great Chain of Being.They both emphasized...As leading figures in English literature during the Neoclassical period,Alexander Pope and Jonathan Swift both showed great concern with the nature of man and his place in the Great Chain of Being.They both emphasized the irreplaceable role of reason in guiding man in his self-positioning in the universe,and pointed out the tragic,pathetic,or detestable fall man was vulnerable to in case of violating the law of nature.Pope attached more importance to setting right man' s position as against God and beast,while Swift showed more interest in the chain of being within the human society;Pope kept warning man against his pride and possible ruin as a result of his ambition,while Swift worried more about man' s degradation due to loss of reason.展开更多
The protected historical blocks always fail to undertake some necessary functions of modern cities because they inherit texture and skyline of historical spaces,and also traditional building density,so these blocks la...The protected historical blocks always fail to undertake some necessary functions of modern cities because they inherit texture and skyline of historical spaces,and also traditional building density,so these blocks lack in popularity and fall into rigid display of folk customs.In view of the contradiction between protection and vitality,this study proposes the concept of"intergrowth between underground space and urban block"on the basis of theoretic researches and construction practices,aims at renovating urban public green spaces by following the principle of regeneration of place,so as to improve and make up modern urban functions of historical blocks,stimulate vitality of the community,provide an effective solution to the development of new cities and renovation of old cities.展开更多
In the context of“stock planning”,the conservation planning of historic blocks and features has become one of the important issues in recent years,which is also of great significance for the regeneration of architec...In the context of“stock planning”,the conservation planning of historic blocks and features has become one of the important issues in recent years,which is also of great significance for the regeneration of architectural heritage value.Based on the theoretical support of Norberg Schulz’s“place spirit”,this paper takes Nanjing Confucius Temple Historic Block as an example to interpret the application of“place spirit”in the protection and renewal of historic block and the inheritance strategy of historical block context.展开更多
Last October, the Nanjing-based aiwan, Hongkong, Macao and verseas Chinese Literature Society went to Wulong Pool. Zhang Chao, vice-chairman of the society, invited me to go to see the place with him. We went eastward...Last October, the Nanjing-based aiwan, Hongkong, Macao and verseas Chinese Literature Society went to Wulong Pool. Zhang Chao, vice-chairman of the society, invited me to go to see the place with him. We went eastward out of Longpanli along bustling and seething Guangzhou Avenue. by the side of the high Suolong Bridge, we found a garden gate with flower-展开更多
The paper had illustrated current status of Chinese temple gardens and background of Wenshu Temple in Chengdu City,analyzed that landscape spatial pattern of Wenshu Temple was characterized by introverted enclosed qua...The paper had illustrated current status of Chinese temple gardens and background of Wenshu Temple in Chengdu City,analyzed that landscape spatial pattern of Wenshu Temple was characterized by introverted enclosed quadrangle courtyard including religious activity zone,life activities zone and garden rest zone.It also discussed the influences of artistic conception of Zen on spirit of place of landscape space in the perspectives of Zen architectural factors,introverted national culture,religious color of architectural space,and cultural landscape.It had proposed that there existed imperfections in later management of greening and landscaping in Wenshu Temple,and some problems such as enclosed space and isolated space from surrounding historical and cultural carrier.It pointed out that landscape perseverance was a long process and it should not restrict to protection of internal environment of carrier space but should enhance restoration of external part and relevant parts to display cultural and economic value of historical and cultural carrier.展开更多
This paper focuses on characteristics studies of Kazak place names in Ili Kazak Autonomous Prefecture based on Univer-sal Principles of Tendencies proposed by the Polish linguist Witold Manczak.Through careful and tho...This paper focuses on characteristics studies of Kazak place names in Ili Kazak Autonomous Prefecture based on Univer-sal Principles of Tendencies proposed by the Polish linguist Witold Manczak.Through careful and thorough study,this paper foundthat because of different traditional lifestyles and different political strategies through different historical periods,this paper provedthat the Kazaks as the nomads were proficient in observing the environmental conditions,and made full use of them to name places.展开更多
Because of its peculiar language environment with multi ethnicities and the One Belt and One Road initiative,the studies of place names in Ili Kazak Autonomous Prefecture attract many linguists’interests.This paper f...Because of its peculiar language environment with multi ethnicities and the One Belt and One Road initiative,the studies of place names in Ili Kazak Autonomous Prefecture attract many linguists’interests.This paper focuses on characteristics studies of Uyghur place names in Ili Kazak Autonomous Prefecture based on Universal Principles of Tendencies proposed by the Polish linguist Witold Manczak.Through careful and thorough study,this paper found that because of different traditional lifestyles and different political strategies through different historical periods,as urban people,the Uyghur place names highlighted the Uyghur people’s great contributions to artificial constructions.展开更多
C57BL/6J and BALB/cJ mice display significant differences in sociability and response to drugs, but the phenotypic variability of their susceptibility to cocaine is still not well known. In this study, the differences...C57BL/6J and BALB/cJ mice display significant differences in sociability and response to drugs, but the phenotypic variability of their susceptibility to cocaine is still not well known. In this study, the differences between these two mice strains in the persistence of cocaine-induced conditioned place preference (CPP), as well as the locomotion and social behaviors after the 24-hour withdrawal from a four-day cocaine (20 mg/kg/day) administration were investigated. The results showed that the cocaine-induced CPP persisted over two weeks in C57BL/6J mice, while it diminished within one week among BALB/cJ mice. After 24-hours of cocaine withdrawal, high levels of locomotion as well as low levels of social interaction and aggressive behavior were found in C57BL/6J mice, but no significant changes were found in BALB/cJ mice, indicating that cocaine-induced CPP persistence, locomotion and social behavior are not consistent between these two strains, and that overall C57BL/6J mice are more susceptible to cocaine than BALB/cJ mice at the tested doses.展开更多
Objective: To determine abundance, distribution and diversity of potential breeding container habitats of the dengue vectors in public places including schools, restaurants,mosques and parks in southwest areas of Pena...Objective: To determine abundance, distribution and diversity of potential breeding container habitats of the dengue vectors in public places including schools, restaurants,mosques and parks in southwest areas of Penang Island, Malaysia.Methods: Premises at restaurants, schools, parks and mosques were surveyed simultaneously and inspected visually for container habitats and production of immature mosquitoes from March 2015 to March 2016. Abundance(mean ± SE) of breeding containers between sites was compared using One-way ANOVA. Independent sample ttest was used to compare total number of Aedes albopictus(Ae. albopictus) and Aedes aegypti(Ae. aegypti) surveyed.Results: The surveyed locations yielded a total of 3 741 breeding containers and 19 537 immature mosquitoes from four areas. Concurrent artificial and natural containers produced 78.4% immature Ae. albopictus and 6.3% Ae. aegypti mosquitoes in wet season,with 14.2% Ae. albopictus and 1.1% Ae. aegypti mosquitoes in dry season. Artificial containers accounted for 98.1% of the total containers recorded, with restaurants being the most productive locations(8 012) and schools being the least productive(2 234).Conclusions: It was concluded that public places are good sources of potential container habitats of Aedes mosquitoes in Penang Island, Malaysia and Ae. albopictus has exclusively replaced the home-grown Ae. aegypti even in urban areas. Therefore, treatment of artificial containers in such locations is critical in Aedes mosquito control campaigns during dengue outbreaks.展开更多
Cultivated land transition and its driving mechanism are the hotspots among studies on land use change. In this study, we constructed a framework to study the driving mechanism of cultivated land transition from the q...Cultivated land transition and its driving mechanism are the hotspots among studies on land use change. In this study, we constructed a framework to study the driving mechanism of cultivated land transition from the quantitative perspective. Based on the vector data of land use in 1990, 2000 and 2009 of Yantai Proper, Shandong Province China, 11 explanatory variables were chosen from two aspects: the elevation, slope, cost distance to major water area and cost distance to minor water area, which presented physical factors; cost distance to district center, cost distance to town center, cost distance to city expansion center, cost distance to major roads, cost distance to city roads, cost distance to county roads and cost distance to rural roads, which presented the socio-economic factors. Combined with spatial analysis tools and Logistic regression analysis model, we construct Logistic regression analyses with four objectives that were urban construction land, rural residential land, orchard and other lands. The results show that, cost distance to district center, cost distance to town center, cost distance to city expansion center and cost distance to city roads are the significant explanatory variables for the transition of cultivated land into urban construction land. The main explained factors on the transition of cultivated land into rural residential land are slope, cost distance to town center, cost distance to county roads and cost distance to rural roads. Slope, cost distance to minor water area, cost distance to town center, cost distance to county roads and cost distance to rural roads are the significant explanatory variables for the transition of cultivated land into orchard land. Elevation, slope, cost distance to major water area and cost distance to minor water area are the main explanatory variables on the transition of cultivated land into other land uses.展开更多
A new type of parallel indexing cam mechanism is discovered.The composition of the cam profile is proposed and the formulas of the mechanism parameters are established by synthesis of its configuration and size.The eq...A new type of parallel indexing cam mechanism is discovered.The composition of the cam profile is proposed and the formulas of the mechanism parameters are established by synthesis of its configuration and size.The equations for working pro- file and pressure angle of the cam are derived based on the inverse model and the derivative of pitch curve of cams.An example is given and demonstrates that it is available to design the new mechanism using the derived expressions.展开更多
Objective: To study the effect of glycine site/NMDA (N-methyl-D-aspartate) receptor antagonist MRZ2/576 on the conditioned place preference (CPP) and locomotor activity induced by morphine in mice. Methods: Different ...Objective: To study the effect of glycine site/NMDA (N-methyl-D-aspartate) receptor antagonist MRZ2/576 on the conditioned place preference (CPP) and locomotor activity induced by morphine in mice. Methods: Different doses (1.25, 2.5 and 5 mg/kg, i.p.) of MRZ2/576 were used to evaluate the effect of MRZ2/576 on the acquisition and expression of CPP induced by morphine (5 mg/kg) in mice. In addition, we examined the locomotor activity of mice in conditioning and testing phase of CPP paradigm. Results: MRZ2/576 alone could not establish place preference, but a 5 mg/kg dose of MRZ2/576 could block both acquisition and expression of morphine-induced CPP. In testing phase of CPP, there was no statistical difference for locomotor activity between the groups; injection of MRZ2/576 showed a dose-dependent decrease of locomotor activity on both control and morphine-treated mice, especially 5 mg/kg of MRZ2/576 significantly suppressed the locomotor activity of mice. Conclusion: Based on the present results, we assume that MRZ2/576 can antagonize the rewarding effect of morphine, suggesting that this glycine site/NMDA receptor antagonist could be used to treat addictions due to its light side effect profile.展开更多
The present study was designed to determine the changes of phosphorylation of cAMP- response ele-ment binding protein (CREB) in hippocampus induced by ohmefentanyl stereoisomers (F9202 and F9204)in conditioned place p...The present study was designed to determine the changes of phosphorylation of cAMP- response ele-ment binding protein (CREB) in hippocampus induced by ohmefentanyl stereoisomers (F9202 and F9204)in conditioned place preference (CPP) paradigm. The results showed that mice receiving F9202 and F9204displayed obvious CPP. They could all significantly stimulate CREB phosphorylation and maintained for along time without affecting total CREB protein levels. The effect of F9204 was similar to morphine whicheffect was more potent and longer than F9202. We also examined the effects of ketamine, a noncompetitiveN-mthyl-D-aspartate receptor (NR) antagonist, on morphine-, F9202- and F9204- induced CPP and phos-phorylation of CREB in hippocampus. Ketamine could suppress not only the place preference but also thephosphorylation of CREB produced by morphine, F9202 and F9204. These findings suggest that alterationsin the phosphorylation of CREB be relevant to opiates signaling and the development of opiates dependence.NR antagonists may interfere with opiates dependence and may have potential therapeutic implications.展开更多
Let f be a proper edge coloring of G using k colors. For each x ∈ V(G), the set of the colors appearing on the edges incident with x is denoted by Sf(x) or simply S(x) if no confusion arise. If S(u) = S(v) ...Let f be a proper edge coloring of G using k colors. For each x ∈ V(G), the set of the colors appearing on the edges incident with x is denoted by Sf(x) or simply S(x) if no confusion arise. If S(u) = S(v) and S(v) S(u) for any two adjacent vertices u and v, then f is called a Smarandachely adjacent vertex distinguishing proper edge col- oring using k colors, or k-SA-edge coloring. The minimum number k for which G has a Smarandachely adjacent-vertex-distinguishing proper edge coloring using k colors is called the Smarandachely adjacent-vertex-distinguishing proper edge chromatic number, or SA- edge chromatic number for short, and denoted by Xsa(G). In this paper, we have discussed the SA-edge chromatic number of K4 V Kn.展开更多
Taking Eighteen-Step Ladder in Chongqing Municipality of China for example,physical space forms of street space structure,space hierarchy,street scale,and unit architectural type were elaborated to explore the relatio...Taking Eighteen-Step Ladder in Chongqing Municipality of China for example,physical space forms of street space structure,space hierarchy,street scale,and unit architectural type were elaborated to explore the relation between spatial characteristics and spirit of place of traditional blocks.展开更多
基金the National Natural Science Foundation of China (Grant No. 41971171)The National Social Science Foundation of China (Grant No. 21BYY098) for funding support
文摘The place and placeness are believed to be a crucial perspective for comprehending the transformative dynamics of tourist destinations in the context of globalization and the rapid development of the tourism industry.As the material carrier of language,linguistic landscape is an intermediary for people to endow emotions and personalities into the place,becoming an effective path for exploring the place-making in a certain area.Mogan Mountain is a famous national tourist resort,which is located in Mogan Mountain Town,Deqing County,Huzhou City,China.This is a good case area for studying the relationship between linguistic landscape and placemaking in tourist destinations.There are two theories that form the theoretical foundation of the study,namely the place and the geosemiotics.Firstly,the results showed the overall style of the linguistic landscape.Multilingual labelling(52.7%),official signs(55.3%),and standardized Chinese characters predominantly shaped the linguistic landscape,with English and other languages being complementary.Secondly,from the perspective of three dimensions of the geosemiotics framework,such as inscription,language preference,and placement position,we conduct a comprehensive semiotic analysis of the linguistic landscape,which encompasses diverse facets such as fonts,materials,shifts in state,text vectors,and symmetrical arrangements.Finally,we explore the influence of linguistic landscapes on the place-making of Mogan Mountain through the dimensions of location,locale,and sense of place.The information on linguistic landscapes indicates the geographical location.These linguistic landscapes play an important role in constructing the language order,nostalgic atmosphere,exotic atmosphere,and elegant and tasteful lifestyle of the public space in Mogan Mountain.Readers of linguistic landscapes,including tourists and residents,generate and identify with the unique sense of place in Mogan Mountain.These linguistic landscapes construct the destination placeness of Mogan Mountain that combines both foreign and nostalgic styles,and the integration of Chinese and Western cultures.It will help promote the image positioning of tourism destinations and have practical guiding significance for the tourism planning,landscape-making,language management,and other aspects of tourism destinations.
文摘In the novel“A Clean,Well-lighted Place”,Hemingway tells the story of two waiters in a Spanish caféjust before closing time,talking about an old man who drank heavily in the caféevery night and lived a wealthy life but still wants to commit suicide.Using the iceberg principle,Hemingway purposely omits the plot,characterization of the story,and uses symbolism and repetition to describe people’s different attitudes facing the spiritual emptiness after the war,breaking the readers’expectations,and inspiring them to explore the meaning of individual life.Therefore,based on Wolfgang Iser and Zhu Liyuan’s appealing structure theory,this paper will analyze the appealing structure in“A Clean,Well-lighted Place”at three levels:meaning construction,rhetorical techniques,and thoughts and themes.It is hoped that readers can find a new way to interpret the short story,better understand the author’s creative ideas and dig deeper into the connotation of the work.
文摘As leading figures in English literature during the Neoclassical period,Alexander Pope and Jonathan Swift both showed great concern with the nature of man and his place in the Great Chain of Being.They both emphasized the irreplaceable role of reason in guiding man in his self-positioning in the universe,and pointed out the tragic,pathetic,or detestable fall man was vulnerable to in case of violating the law of nature.Pope attached more importance to setting right man' s position as against God and beast,while Swift showed more interest in the chain of being within the human society;Pope kept warning man against his pride and possible ruin as a result of his ambition,while Swift worried more about man' s degradation due to loss of reason.
基金Supported by the Youth Foundation of Humanities and Social Sciences Program,Ministry of Education(12YJCZH032)
文摘The protected historical blocks always fail to undertake some necessary functions of modern cities because they inherit texture and skyline of historical spaces,and also traditional building density,so these blocks lack in popularity and fall into rigid display of folk customs.In view of the contradiction between protection and vitality,this study proposes the concept of"intergrowth between underground space and urban block"on the basis of theoretic researches and construction practices,aims at renovating urban public green spaces by following the principle of regeneration of place,so as to improve and make up modern urban functions of historical blocks,stimulate vitality of the community,provide an effective solution to the development of new cities and renovation of old cities.
文摘In the context of“stock planning”,the conservation planning of historic blocks and features has become one of the important issues in recent years,which is also of great significance for the regeneration of architectural heritage value.Based on the theoretical support of Norberg Schulz’s“place spirit”,this paper takes Nanjing Confucius Temple Historic Block as an example to interpret the application of“place spirit”in the protection and renewal of historic block and the inheritance strategy of historical block context.
文摘Last October, the Nanjing-based aiwan, Hongkong, Macao and verseas Chinese Literature Society went to Wulong Pool. Zhang Chao, vice-chairman of the society, invited me to go to see the place with him. We went eastward out of Longpanli along bustling and seething Guangzhou Avenue. by the side of the high Suolong Bridge, we found a garden gate with flower-
基金Supported by Funds of Undergraduate Cultivation Plan Project of Sichuan Agricultural University~~
文摘The paper had illustrated current status of Chinese temple gardens and background of Wenshu Temple in Chengdu City,analyzed that landscape spatial pattern of Wenshu Temple was characterized by introverted enclosed quadrangle courtyard including religious activity zone,life activities zone and garden rest zone.It also discussed the influences of artistic conception of Zen on spirit of place of landscape space in the perspectives of Zen architectural factors,introverted national culture,religious color of architectural space,and cultural landscape.It had proposed that there existed imperfections in later management of greening and landscaping in Wenshu Temple,and some problems such as enclosed space and isolated space from surrounding historical and cultural carrier.It pointed out that landscape perseverance was a long process and it should not restrict to protection of internal environment of carrier space but should enhance restoration of external part and relevant parts to display cultural and economic value of historical and cultural carrier.
文摘This paper focuses on characteristics studies of Kazak place names in Ili Kazak Autonomous Prefecture based on Univer-sal Principles of Tendencies proposed by the Polish linguist Witold Manczak.Through careful and thorough study,this paper foundthat because of different traditional lifestyles and different political strategies through different historical periods,this paper provedthat the Kazaks as the nomads were proficient in observing the environmental conditions,and made full use of them to name places.
文摘Because of its peculiar language environment with multi ethnicities and the One Belt and One Road initiative,the studies of place names in Ili Kazak Autonomous Prefecture attract many linguists’interests.This paper focuses on characteristics studies of Uyghur place names in Ili Kazak Autonomous Prefecture based on Universal Principles of Tendencies proposed by the Polish linguist Witold Manczak.Through careful and thorough study,this paper found that because of different traditional lifestyles and different political strategies through different historical periods,as urban people,the Uyghur place names highlighted the Uyghur people’s great contributions to artificial constructions.
基金Foundation items: This research was supported by the National Nat- ural Science Foundation of China (31260513), the National Natural Science Foundation of Ningxia (NZ14077) and the Science Foundation of Beifang University of Nationalities (2012Y052)
文摘C57BL/6J and BALB/cJ mice display significant differences in sociability and response to drugs, but the phenotypic variability of their susceptibility to cocaine is still not well known. In this study, the differences between these two mice strains in the persistence of cocaine-induced conditioned place preference (CPP), as well as the locomotion and social behaviors after the 24-hour withdrawal from a four-day cocaine (20 mg/kg/day) administration were investigated. The results showed that the cocaine-induced CPP persisted over two weeks in C57BL/6J mice, while it diminished within one week among BALB/cJ mice. After 24-hours of cocaine withdrawal, high levels of locomotion as well as low levels of social interaction and aggressive behavior were found in C57BL/6J mice, but no significant changes were found in BALB/cJ mice, indicating that cocaine-induced CPP persistence, locomotion and social behavior are not consistent between these two strains, and that overall C57BL/6J mice are more susceptible to cocaine than BALB/cJ mice at the tested doses.
基金Funded by a grant from Universiti Sains Malaysia(Grant No.1001/PBIOLOGI/811277)
文摘Objective: To determine abundance, distribution and diversity of potential breeding container habitats of the dengue vectors in public places including schools, restaurants,mosques and parks in southwest areas of Penang Island, Malaysia.Methods: Premises at restaurants, schools, parks and mosques were surveyed simultaneously and inspected visually for container habitats and production of immature mosquitoes from March 2015 to March 2016. Abundance(mean ± SE) of breeding containers between sites was compared using One-way ANOVA. Independent sample ttest was used to compare total number of Aedes albopictus(Ae. albopictus) and Aedes aegypti(Ae. aegypti) surveyed.Results: The surveyed locations yielded a total of 3 741 breeding containers and 19 537 immature mosquitoes from four areas. Concurrent artificial and natural containers produced 78.4% immature Ae. albopictus and 6.3% Ae. aegypti mosquitoes in wet season,with 14.2% Ae. albopictus and 1.1% Ae. aegypti mosquitoes in dry season. Artificial containers accounted for 98.1% of the total containers recorded, with restaurants being the most productive locations(8 012) and schools being the least productive(2 234).Conclusions: It was concluded that public places are good sources of potential container habitats of Aedes mosquitoes in Penang Island, Malaysia and Ae. albopictus has exclusively replaced the home-grown Ae. aegypti even in urban areas. Therefore, treatment of artificial containers in such locations is critical in Aedes mosquito control campaigns during dengue outbreaks.
基金Under the auspices of National Natural Science Foundation of China(No.41130748)
文摘Cultivated land transition and its driving mechanism are the hotspots among studies on land use change. In this study, we constructed a framework to study the driving mechanism of cultivated land transition from the quantitative perspective. Based on the vector data of land use in 1990, 2000 and 2009 of Yantai Proper, Shandong Province China, 11 explanatory variables were chosen from two aspects: the elevation, slope, cost distance to major water area and cost distance to minor water area, which presented physical factors; cost distance to district center, cost distance to town center, cost distance to city expansion center, cost distance to major roads, cost distance to city roads, cost distance to county roads and cost distance to rural roads, which presented the socio-economic factors. Combined with spatial analysis tools and Logistic regression analysis model, we construct Logistic regression analyses with four objectives that were urban construction land, rural residential land, orchard and other lands. The results show that, cost distance to district center, cost distance to town center, cost distance to city expansion center and cost distance to city roads are the significant explanatory variables for the transition of cultivated land into urban construction land. The main explained factors on the transition of cultivated land into rural residential land are slope, cost distance to town center, cost distance to county roads and cost distance to rural roads. Slope, cost distance to minor water area, cost distance to town center, cost distance to county roads and cost distance to rural roads are the significant explanatory variables for the transition of cultivated land into orchard land. Elevation, slope, cost distance to major water area and cost distance to minor water area are the main explanatory variables on the transition of cultivated land into other land uses.
文摘A new type of parallel indexing cam mechanism is discovered.The composition of the cam profile is proposed and the formulas of the mechanism parameters are established by synthesis of its configuration and size.The equations for working pro- file and pressure angle of the cam are derived based on the inverse model and the derivative of pitch curve of cams.An example is given and demonstrates that it is available to design the new mechanism using the derived expressions.
基金Project supported by the National Basic Research Program (973) of China (No. 2003CB515402), and the Science and Technology Coun-cil of Zhejiang Province (No. 2005C23G2010166), China
文摘Objective: To study the effect of glycine site/NMDA (N-methyl-D-aspartate) receptor antagonist MRZ2/576 on the conditioned place preference (CPP) and locomotor activity induced by morphine in mice. Methods: Different doses (1.25, 2.5 and 5 mg/kg, i.p.) of MRZ2/576 were used to evaluate the effect of MRZ2/576 on the acquisition and expression of CPP induced by morphine (5 mg/kg) in mice. In addition, we examined the locomotor activity of mice in conditioning and testing phase of CPP paradigm. Results: MRZ2/576 alone could not establish place preference, but a 5 mg/kg dose of MRZ2/576 could block both acquisition and expression of morphine-induced CPP. In testing phase of CPP, there was no statistical difference for locomotor activity between the groups; injection of MRZ2/576 showed a dose-dependent decrease of locomotor activity on both control and morphine-treated mice, especially 5 mg/kg of MRZ2/576 significantly suppressed the locomotor activity of mice. Conclusion: Based on the present results, we assume that MRZ2/576 can antagonize the rewarding effect of morphine, suggesting that this glycine site/NMDA receptor antagonist could be used to treat addictions due to its light side effect profile.
文摘The present study was designed to determine the changes of phosphorylation of cAMP- response ele-ment binding protein (CREB) in hippocampus induced by ohmefentanyl stereoisomers (F9202 and F9204)in conditioned place preference (CPP) paradigm. The results showed that mice receiving F9202 and F9204displayed obvious CPP. They could all significantly stimulate CREB phosphorylation and maintained for along time without affecting total CREB protein levels. The effect of F9204 was similar to morphine whicheffect was more potent and longer than F9202. We also examined the effects of ketamine, a noncompetitiveN-mthyl-D-aspartate receptor (NR) antagonist, on morphine-, F9202- and F9204- induced CPP and phos-phorylation of CREB in hippocampus. Ketamine could suppress not only the place preference but also thephosphorylation of CREB produced by morphine, F9202 and F9204. These findings suggest that alterationsin the phosphorylation of CREB be relevant to opiates signaling and the development of opiates dependence.NR antagonists may interfere with opiates dependence and may have potential therapeutic implications.
基金Supported by NNSF of China(61163037,61163054,61363060)
文摘Let f be a proper edge coloring of G using k colors. For each x ∈ V(G), the set of the colors appearing on the edges incident with x is denoted by Sf(x) or simply S(x) if no confusion arise. If S(u) = S(v) and S(v) S(u) for any two adjacent vertices u and v, then f is called a Smarandachely adjacent vertex distinguishing proper edge col- oring using k colors, or k-SA-edge coloring. The minimum number k for which G has a Smarandachely adjacent-vertex-distinguishing proper edge coloring using k colors is called the Smarandachely adjacent-vertex-distinguishing proper edge chromatic number, or SA- edge chromatic number for short, and denoted by Xsa(G). In this paper, we have discussed the SA-edge chromatic number of K4 V Kn.
基金Supported by Special Fund of College of Landscape Architecture,Sichuan Agricultural University
文摘Taking Eighteen-Step Ladder in Chongqing Municipality of China for example,physical space forms of street space structure,space hierarchy,street scale,and unit architectural type were elaborated to explore the relation between spatial characteristics and spirit of place of traditional blocks.