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An Analysis on the Causes of Clyde Griffiths' Tragedy in An American Tragedy 被引量:1
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作者 吴国剑 余孝平 《海外英语》 2010年第10X期215-217,共3页
An American Tragedy is one of the most representative novels of Theodore Dreiser.The novel tells a story of Clyde Griffiths' corruption from an innocent boy into a murderer by pursuing pleasure and high status.Thi... An American Tragedy is one of the most representative novels of Theodore Dreiser.The novel tells a story of Clyde Griffiths' corruption from an innocent boy into a murderer by pursuing pleasure and high status.This paper analyses Clyde's tragedy causes from the historic social environment and the weakness in his personality.The paper can be divided into four chapters.The first chapter is introduction;including the background and meaning of study.The second chapter is the plot of the novel and introduces the main characters.The chapter three analyses the main causes which results in protagonist's tragedy,including social factors,family factors as well as character factors.In the last chapter the writer makes a conclusion that Clyde's tragedy is both the tragedy of himself and the tragedy of bourgeoisie.He is also a victim under capitalist system. 展开更多
关键词 AN AMERICAN TRAGEDY CORRUPTION social environment egotism
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The Equality–Inequality Dialectics
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作者 Amos AvnyOmnidev International Yehud Israel 《Journal of Philosophy Study》 2020年第6期337-346,共10页
The assay argues that the Equality-Inequality dialectics is a very complex issue,which reflects many social dilemmas.On one side are the state official commitments to secure,maintain and protect all kinds of formal eq... The assay argues that the Equality-Inequality dialectics is a very complex issue,which reflects many social dilemmas.On one side are the state official commitments to secure,maintain and protect all kinds of formal equalities.On the other side are the natural and genetic distinctions that differ between human-beings while creating and maintaining inequality.In fact,this is kind of a contradiction exists in many fields of social sciences.The essay’s author reviews some of the relevant historical events,such as social mobility,individualism and education and points out on future solutions.Among the proposed suggestions are:1)Embracing Frankl’s giving“Meaning to Life”as a leverage for increasing pleasure of life;2)Recognizing and promoting Creative Individualism as the legitimized ground for inequality;3)Increasing Social Cohesion,required for social empowerment and attaining security and happiness. 展开更多
关键词 equality and inequality social mobility educational inequality capitalist egotism creative individualism meaning of life
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脑钠肽通过调控lncRNA EGOT缓解低氧诱导的大鼠心肌细胞损伤 被引量:4
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作者 吴彩霞 张小兰 郭梦 《临床和实验医学杂志》 2019年第19期2020-2023,共4页
目的探讨脑钠肽(BNP)通过调控长链非编码RNA嗜酸性粒细胞转录因子(lncRNA EGOT)缓解低氧诱导的心肌细胞损伤的效果与机制。方法选择6~8周龄健康成年SD大鼠分离原代心肌细胞,然后分为三组:正常组、低氧培养组(模型组)、BNP干预缺氧组(实... 目的探讨脑钠肽(BNP)通过调控长链非编码RNA嗜酸性粒细胞转录因子(lncRNA EGOT)缓解低氧诱导的心肌细胞损伤的效果与机制。方法选择6~8周龄健康成年SD大鼠分离原代心肌细胞,然后分为三组:正常组、低氧培养组(模型组)、BNP干预缺氧组(实验组),每组设3个复孔。开始低氧时,正常对照组给予无血清培养基继续培养16 h;模型组弃去培养液,加入100μl低氧液通入95%氮气+5%CO 2混合气体10 min继续培养16 h;实验组于低氧前给予BNP(20 ng/ml)培养2 h。细胞处理后24 h与48 h后,采用四甲基偶氮唑盐(MTT)比色法检测细胞增殖情况,qRT-PCR检测lncRNA EGOT表达水平,酶联免疫吸附法检测超氧化物歧化酶(SOD)与BNP表达水平,Western blot法检测Bcl-2、Caspase-3蛋白表达水平。结果细胞处理后24 h与48 h后,模型组与实验组的细胞存活率、lncRNA EGOT相对表达量显著低于正常组(P<0.05),实验组高于模型组(P<0.05)。BNP、SOD表达量和Bcl-2、Caspase-3蛋白相对表达量显著高于正常组(P<0.05),实验组低于模型组(P<0.05)。三组细胞存活率、lncRNA EGOT、BNP、SOD、Bcl-2和Caspase-3表达在处理24 h和48 h这两个时间点比较无显著差异。结论BNP能通过促进lncRNA EGOT的表达,抑制Bcl-2、Caspase-3蛋白的表达,从而缓解低氧诱导的心肌细胞损伤,此过程不具有时间依赖性。 展开更多
关键词 大鼠 心肌细胞损伤 脑钠肽 lncRNA EGOT 低氧
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