Introduction: Fractional radiofrequency (RF) technology has been shown to be a gold standard therapy for acne scars. We have previously published clinical and histological results from the treatment of 8 patients with...Introduction: Fractional radiofrequency (RF) technology has been shown to be a gold standard therapy for acne scars. We have previously published clinical and histological results from the treatment of 8 patients with active acne and acne related scarring using a fractional RF device. Evidence of safety and efficacy was demonstrated, including long term follow-up clinical results from 4 patients, up to two years post last fractional treatment. In the current article we present histology evidence of acne scar skin renewal 3.5 years post treatment. Methods: Skin biopsies from acne scars in a concealed facial area were taken before, after four treatments and at 3.5 years after the last fractional treatment. Biopsies were examined with standard hematoxylin and eosin (H&E) stain, as well as Verhoeff’s Van Gieson (VVG) and Shikata stains for elastic fibers. Results: Histological findings demonstrate regeneration of elastic fibers and reduction of the dermal fibrosis. Scar depth of Patient #2 was reduced by 80% in the corresponding follow-up period. Conclusion: The long-term histological results further support the previously published findings that fractional RF is a safe and effective treatment for acne related scars.展开更多
Polymer rheology has a long research tradition and holds an important position in the scientific community.It is supposed to be a valuable subject to the vast polymer industry.This article points out the exciting deve...Polymer rheology has a long research tradition and holds an important position in the scientific community.It is supposed to be a valuable subject to the vast polymer industry.This article points out the exciting developments that are transforming our understanding of the world of polymer rheology.We discuss not only the emerging challenges in the area but also how China might wish to seize the moment,pick up the trend and take advantage of the potential economic benefits to the huge petro-chemical industry of China.展开更多
文摘Introduction: Fractional radiofrequency (RF) technology has been shown to be a gold standard therapy for acne scars. We have previously published clinical and histological results from the treatment of 8 patients with active acne and acne related scarring using a fractional RF device. Evidence of safety and efficacy was demonstrated, including long term follow-up clinical results from 4 patients, up to two years post last fractional treatment. In the current article we present histology evidence of acne scar skin renewal 3.5 years post treatment. Methods: Skin biopsies from acne scars in a concealed facial area were taken before, after four treatments and at 3.5 years after the last fractional treatment. Biopsies were examined with standard hematoxylin and eosin (H&E) stain, as well as Verhoeff’s Van Gieson (VVG) and Shikata stains for elastic fibers. Results: Histological findings demonstrate regeneration of elastic fibers and reduction of the dermal fibrosis. Scar depth of Patient #2 was reduced by 80% in the corresponding follow-up period. Conclusion: The long-term histological results further support the previously published findings that fractional RF is a safe and effective treatment for acne related scars.
基金国家自然科学基金项目，天津市应用基础与前沿技术研究计划重点项目(14JCZDJC35900)National Natural Science Foundation of China，Tianjin Research Program of Application Foundation and Advanced Technology
基金sponsored by the National Natural Science Foundation of China (Grant No. 20910302023).I thank Dr. Lijia An, the director of CIAC, for arranging and accommodating this short course and appreciate the NNSFC's support to advance the science of polymer rheology in China.This article is actually prompted by the interest from NNSFC to explore the future of polymer rheology.The work is supported, in part, by grants (DMR-0821697 and CMMI-0926522) from the National Science Foundation of the United States
文摘Polymer rheology has a long research tradition and holds an important position in the scientific community.It is supposed to be a valuable subject to the vast polymer industry.This article points out the exciting developments that are transforming our understanding of the world of polymer rheology.We discuss not only the emerging challenges in the area but also how China might wish to seize the moment,pick up the trend and take advantage of the potential economic benefits to the huge petro-chemical industry of China.
