Microelectronic neural bridging of toad nerves to restore leg function

The present study used a microelectronic neural bridge comprised of electrode arrays for neural signal detection, functional electrical stimulation, and a microelectronic circuit including signal amplifying, processing, and functional electrical stimulation to bridge two separate nerves, and to restore the lost function of one nerve. The left leg of one spinal toad was subjected to external mechanical stimulation and functional electrical stimulation driving. The function of the left leg of one spinal toad was regenerated to the corresponding leg of another spinal toad using a microelectronic neural bridge. Oscilloscope tracings showed that the electromyographic signals from controlled spinal toads were generated by neural signals that controlled the spinal toad, and there was a delay between signals. This study demonstrates that microelectronic neural bridging can be used to restore neural function between different injured nerves.

应用小面积体表电极对穴位进行功能电刺激实现五指屈曲的实验研究

为肢体瘫痪这一重大残障疾病的康复治疗探索一种生物医学工程技术。根据首次提出的针灸结合肌电桥治疗中风偏瘫的新思路,采用小面积体表电极,选取10名健康志愿者(5男5女),通过对每位志愿者上肢216组穴位组合进行功能电刺激,确定控制五指屈动作的最佳刺激穴位组合。实验发现,5对实现五指屈曲的最佳穴位组合,其电流阈值均小于10 m A,指屈动作完成率为100%,舒适率在90%以上,其他指屈无反应率在80%以上。相对于传统在肌肉上进行功能电刺激控制五指指屈的方法,对穴位进行功能电刺激,刺激电流小,动作纯净度更高,刺激位点定位更容易,为进一步开展偏瘫患者以自身健康五指动作带动瘫侧五指动作的临床试验打下基础。

双桥运动时下肢肌的肌电分析

目的：了解双桥运动时偏瘫病人下肢主要屈伸肌群的收缩情况。方法：测定１０例正常人和３６例偏瘫病人在双桥运动时股四头肌、绳肌、胫前肌和小腿三头肌的表面积分肌电值，并比较两侧同名肌的比值。结果：双桥运动时，仅大腿肌有明显的肌电活动，正常人两侧对称（Ｐ＞００５），偏瘫病人患侧大腿肌的肌电变化明显低于健侧（Ｐ＜００５）；小腿肌在运动前后肌电变化不明显。结论：双桥运动对抑制偏瘫病人下肢的协同模式有利。