Derived from dry powder coating of metals, electrostatic powder coating for pharmaceuticals is a technology for coating drug solid dosage forms. In this technology, coating powders, containing coating polymers, pigmen...Derived from dry powder coating of metals, electrostatic powder coating for pharmaceuticals is a technology for coating drug solid dosage forms. In this technology, coating powders, containing coating polymers, pigments, and other excipients, are directly sprayed onto the surface of the solid dosage forms through an electrostatic gun without using any organic solvent or water. The deposited coating powders are further cured to form a coating film. Electrostatic powder coating technology has many advantages compared to other pharmaceutical coating methods. It can eliminate the limitations caused by the organic solvent in solvent coating such as environmental issues and health problems. And electrostatic powder coating technology also surpasses aqueous coating due to its shorter processing time and less energy consumption, leading to a lower overall cost. Furthermore, the utilization of electrical attraction can promote the movement of coating powders towards the substrate, leading to an enhanced coating powder adhesion and coating efficiency, which make it more promising compared to other dry coating technologies. The objective of this review is to summarize the coating principles, apparatus, and formulations of different electrostatic powder coating technologies, giving their advantages and limitations and also analyzing the future application in the industry for each technology展开更多
Electric fields induced by ring and pin electrodes in electrostatic charged powder sprayingtechnique are analysed. The fundamental formulae to deseribe these fields have been built up. Theseformulae could be used to d...Electric fields induced by ring and pin electrodes in electrostatic charged powder sprayingtechnique are analysed. The fundamental formulae to deseribe these fields have been built up. Theseformulae could be used to design electrostatic charged podwer spraying system. The chargingeffectiveness of ring and pin electrode is experimentally investigated and compared each other. Theperformance of ring electrode is better than that of pin electrode.展开更多
Particle interactions play a significant role in controlling the performance of dry powder inhalers （DPIs）, which mainly arise through van der Waals potentials, electrostatic interactions, and capillary forces. Our ...Particle interactions play a significant role in controlling the performance of dry powder inhalers （DPIs）, which mainly arise through van der Waals potentials, electrostatic interactions, and capillary forces. Our aim is to investigate the influence of electrostatic charge on the performance of DPIs as a basis for improv- ing the formulation of the particle ingredients. The mixing process of carrier and active pharmaceutical ingredient （API） particles in a vibrating container is investigated using a discrete element method （DEM）. The number of APl particles attaching to the carrier particle （i.e., contact number） increases with increas- ing charge and decreases with increasing container size. The contact number decreases with increasing vibrational velocity amplitude and frequency. Moreover, a mechanism governed by the electrostatic force is proposed for the mixing process. This mechanism is different from that previously proposed for the mixing process governed by van der Waals forces, indicating that long-range and short-range adhesive forces can result in different mixing behaviours.展开更多
Powder coating is an important process in the food industry,especially for snack foods such as potato chips,to create variety in food products.Electrostatic coating has been adopted in order to provide better transfer...Powder coating is an important process in the food industry,especially for snack foods such as potato chips,to create variety in food products.Electrostatic coating has been adopted in order to provide better transfer efficiency and lower the dust produced during coating.Studying the effect of electrode voltage on coating efficiency and evenness of baked potato chips using the developed electrostatic powder coating system was the main purpose of this research.Different types of NaCl(refined and table salts)were coated on baked potato chips at 0,30,40,50,60,and 70 kV.After coating with either refined or table salt,transfer efficiency,adhesion after coating,coating evenness and texture of samples were determined.Higher transfer efficiency,adhesion and coating evenness were observed when electrostatic coating was conducted at 30-50 kV.Most samples with higher transfer efficiency,adhesion and evenness were obtained after electrostatic coating.However,it did not significantly affect hardness of baked potato chips.展开更多
文摘Derived from dry powder coating of metals, electrostatic powder coating for pharmaceuticals is a technology for coating drug solid dosage forms. In this technology, coating powders, containing coating polymers, pigments, and other excipients, are directly sprayed onto the surface of the solid dosage forms through an electrostatic gun without using any organic solvent or water. The deposited coating powders are further cured to form a coating film. Electrostatic powder coating technology has many advantages compared to other pharmaceutical coating methods. It can eliminate the limitations caused by the organic solvent in solvent coating such as environmental issues and health problems. And electrostatic powder coating technology also surpasses aqueous coating due to its shorter processing time and less energy consumption, leading to a lower overall cost. Furthermore, the utilization of electrical attraction can promote the movement of coating powders towards the substrate, leading to an enhanced coating powder adhesion and coating efficiency, which make it more promising compared to other dry coating technologies. The objective of this review is to summarize the coating principles, apparatus, and formulations of different electrostatic powder coating technologies, giving their advantages and limitations and also analyzing the future application in the industry for each technology
文摘Electric fields induced by ring and pin electrodes in electrostatic charged powder sprayingtechnique are analysed. The fundamental formulae to deseribe these fields have been built up. Theseformulae could be used to design electrostatic charged podwer spraying system. The chargingeffectiveness of ring and pin electrode is experimentally investigated and compared each other. Theperformance of ring electrode is better than that of pin electrode.
文摘Particle interactions play a significant role in controlling the performance of dry powder inhalers （DPIs）, which mainly arise through van der Waals potentials, electrostatic interactions, and capillary forces. Our aim is to investigate the influence of electrostatic charge on the performance of DPIs as a basis for improv- ing the formulation of the particle ingredients. The mixing process of carrier and active pharmaceutical ingredient （API） particles in a vibrating container is investigated using a discrete element method （DEM）. The number of APl particles attaching to the carrier particle （i.e., contact number） increases with increas- ing charge and decreases with increasing container size. The contact number decreases with increasing vibrational velocity amplitude and frequency. Moreover, a mechanism governed by the electrostatic force is proposed for the mixing process. This mechanism is different from that previously proposed for the mixing process governed by van der Waals forces, indicating that long-range and short-range adhesive forces can result in different mixing behaviours.
基金This work was supported by a grant from Thailand Research Funding and Office of the Higher Education Commission,contract no.MRG6080261.
文摘Powder coating is an important process in the food industry,especially for snack foods such as potato chips,to create variety in food products.Electrostatic coating has been adopted in order to provide better transfer efficiency and lower the dust produced during coating.Studying the effect of electrode voltage on coating efficiency and evenness of baked potato chips using the developed electrostatic powder coating system was the main purpose of this research.Different types of NaCl(refined and table salts)were coated on baked potato chips at 0,30,40,50,60,and 70 kV.After coating with either refined or table salt,transfer efficiency,adhesion after coating,coating evenness and texture of samples were determined.Higher transfer efficiency,adhesion and coating evenness were observed when electrostatic coating was conducted at 30-50 kV.Most samples with higher transfer efficiency,adhesion and evenness were obtained after electrostatic coating.However,it did not significantly affect hardness of baked potato chips.
