Acoustic emission(AE)source localization is a fundamental element of rock fracture damage imaging.To improve the efficiency and accuracy of AE source localization,this paper proposes a joint method comprising a three-...Acoustic emission(AE)source localization is a fundamental element of rock fracture damage imaging.To improve the efficiency and accuracy of AE source localization,this paper proposes a joint method comprising a three-dimensional(3D)AE source localization simplex method and grid search scanning.Using the concept of the geometry of simplexes,tetrahedral iterations were first conducted to narrow down the suspected source region.This is followed by a process of meshing the region and node searching to scan for optimal solutions,until the source location is determined.The resulting algorithm was tested using the artificial excitation source localization and uniaxial compression tests,after which the localization results were compared with the simplex and exhaustive methods.The results revealed that the localization obtained using the proposed method is more stable and can be effectively avoided compared with the simplex localization method.Furthermore,compared with the global scanning method,the proposed method is more efficient,with an average time of 10%–20%of the global scanning localization algorithm.Thus,the proposed algorithm is of great significance for laboratory research focused on locating rupture damages sustained by large-sized rock masses or test blocks.展开更多
Humpback whales are migratory, spending summers in cooler, high-latitude waters and mating and calving in tropical and subtropical waters in 14 identified district population segments. It may be possible that the coas...Humpback whales are migratory, spending summers in cooler, high-latitude waters and mating and calving in tropical and subtropical waters in 14 identified district population segments. It may be possible that the coastal areas are infected with low pathogenic avian influenza (LPAI) during the release of infected humpback whale feces. Therefore, humpback whales can be an effective reservoir of the avian influenza virus (AIV) from the Poles to the Continents to spread AIV to coastal animals. Strong ultraviolet (UV) exposure amidst CO2 emission increase and minimal sunspot number might cause mutations of aquatic virus and humpback whale in the Antarctic and the Arctic. LPAI or highly pathogenic avian influenza (HPAI) is expressed in the Continents under appropriate environmental factors. Since penguins are birds while humpback whales are marine mammals, the humpback whales infected by the mutant virus might cause interspecies transmission to a new host with evolutionary changes. The migration pattern is seasonally similar between migratory bird and humpback whale except: 1) different species of bird versus whale, 2) different landing area of land versus coast, 3) similar infection means of bird feces versus humpback whale feces. The contribution of AIV transmission by whales was several times larger than that by migratory birds. Therefore, the routes of humpback whales should be considered to prevent AIV outbreaks in addition to the flyways of migratory birds. Humpback whale stranding (y) along the Atlantic Coast of the USA was correlated with CO2 emissions (x) to have y = 0.3515x + 18.595 (R2 = 0.4069) during 1992-2016 while y = 0.0652x + 4.5847, (R2 = 0.6128) during 2016-2018. AIV outbreak in 2010 (y) along the Atlantic Coast was also correlated with humpback whale stranding (2016-2018) (x) as y = 0.1387x + 6.8184 (R2 = 0.3966). Since AIV outbreak was linearly (R2 = 0.9967) correlated with the minimum sunspot number, it was postulated that the unusual mortality events of humpback whale stranding might be caused by an infected mutant virus in the Arctic. Consequently, the humpback whales were stranded along major CO2 producing Atlantic Coast States toward the winter habitat of the West Indies during the CO2 emissions and the minimal sunspot number with strong UV radiation. The stranded dead whales should be burned as soon as possible to prevent further deadly viral interspecies transmission of AIV by the coastal animals. Since CO2 emissions were increased in 2017 and the sunspot number was minimal at the end of 2018, serious numbers of whales are expected to be stranded at the Gulf of Maine, States of North Carolina, New York, and Virginia from November 2018 till April 2019. To save humpback whales from the unusual mortality event along the Atlantic Coast, the reduction of CO2 emissions is suggested by replacement of fossil fuels combustion plants with nuclear power plants along the Atlantic Coast of the USA.展开更多
Tomographic gamma scanner(TGS),an advancedγ-ray nondestructive analysis technique,can locate and analyze nuclides in radioactive nuclear waste,and TGS can be categorized into two processes:e.g.,transmission measureme...Tomographic gamma scanner(TGS),an advancedγ-ray nondestructive analysis technique,can locate and analyze nuclides in radioactive nuclear waste,and TGS can be categorized into two processes:e.g.,transmission measurement and emission measurement.Specifically,transmission measurements provide the basis for accurate measurement of nonuniform radionuclide content in TGS scanning.The scan data were obtained using the Monte Carlo tool Geant4 simulation,and 25 voxels were divided into five lengths and five widths in a square barrel.In this study,an encoding cropping algorithm based on draped foot vector judgment was adopted to rapidly calculate the voxel trace matrix within a square bucket of nuclear waste,and the transmission images were reconstructed using ordered subset expectation maximization.The results indicated that the cropping speed of the improved coding algorithm was significantly higher than that of the original algorithm,and the relative mean deviation and root-mean-square error between the reconstructed attenuation coefficient and the reference standard value tended to decrease with an increase in the cropped line segments in the voxel;the Pearson correlation coefficient tended to converge to 1.0.The image quality evaluation parameters of the high media-density materials were better than those of the low media-density materials in the above three indexes.The reconstruction effect was relatively poor for more complex filling materials.When there were more than 10 cropped line segments in the voxel,the reconstruction data generally tended to be stable.The graphical trimming algorithm can rapidly calculate the trace matrix of the scanned voxels;it exhibits the advantages of speed and efficiency and can serve as a novel method to solve the trace matrix of TGS nuclear waste transmission scans.展开更多
This paper presents a serial synchronous scanning mode in fiat panel display (FPD) by adding a latch buffer between the serializer and the driving buffer. Comparing with conventional techniques, the proposed structu...This paper presents a serial synchronous scanning mode in fiat panel display (FPD) by adding a latch buffer between the serializer and the driving buffer. Comparing with conventional techniques, the proposed structure can efficiently reduce the brightness loss and improve the transmission performance. Theoretical analysis and experimental results show that the ratio between the lightest weight display time and the relative transmission time is a tradeoff between brightness loss and transmission efficiency.展开更多
Scanning transmission electron microscopy(STEM) has been shown as powerful tools for material characterization,especially after the appearance of aberration-corrector which greatly enhances the resolution of STEM. H...Scanning transmission electron microscopy(STEM) has been shown as powerful tools for material characterization,especially after the appearance of aberration-corrector which greatly enhances the resolution of STEM. High angle annular dark field(HAADF) and annular bright field(ABF) imaging of the aberration-corrected STEM are widely used due to their high-resolution capabilities and easily interpretable image contrasts. However, HAADF mode of the STEM is still limited in detecting light elements due to the weak electron-scattering power. ABF mode of the STEM could detect light and heavy elements simultaneously, providing unprecedented opportunities for probing unknown structures of materials. Atomiclevel structure investigation of materials has been achieved by means of these imaging modes, which is invaluable in many fields for either improving properties of materials or developing new materials. This paper aims to provide a introduction of HAADF and ABF imaging techniques and reviews their applications in characterization of cathode materials, study of electrochemical reaction mechanisms, and exploring the effective design of lithium-ion batteries(LIBs). The future prospects of the STEM are also discussed.展开更多
Existing technologies used to detect monosodium urate(MSU)crystals for gout diagnosis are not ideal due to their low sensitivity and complexity of operation.The purpose of this study was to explore whether aggregation...Existing technologies used to detect monosodium urate(MSU)crystals for gout diagnosis are not ideal due to their low sensitivity and complexity of operation.The purpose of this study was to explore whether aggregation-induced emission luminogens(AIEgens)can be used for highly specific imaging of MSU crystals to assist in the diagnosis of gout.First,we developed a series of luminogens(i.e.,tetraphenyl ethylene(TPE)-NH_(2),TPE-2NH_(2),TPE-4NH_(2),TPE-COOH,TPE-2COOH,TPE-4COOH,and TPE-Ketoalkyne),each of which was then evenly mixed with MSU crystals.Next,optimal fluorescence imaging of each of the luminogens was characterized by a confocal laser scanning microscope(CLSM).This approach was used for imaging standard samples of MSU,hydroxyapatite(HAP)crystals,and mixed samples with 1:1 mass ratio of MSU/HAP.We also imaged samples from mouse models of acute gouty arthritis,HAP deposition disease,and comorbidities of interest.Subsequently,CLSM imaging results were compared with those of compensated polarized light microscopy,and we assessed the biosafety of TPE-Ketoalkyne in the RAW264.7 cell line.Finally,CLSM time series and three-dimensional imaging were performed on MSU crystal samples from human gouty synovial fluid and tophi.As a promising candidate for MSU crystal labeling,TPE-Ketoalkyne was found to detect MSU crystals accurately and rapidly in standard samples,animal samples,and human samples,and could precisely distinguish gout from HAP deposition disease.This work demonstrates that TPE-Ketoalkyne is suitable for highly specific and timely imaging of MSU crystals in gouty arthritis and may facilitate future research on MSU crystal-related diseases.展开更多
BACKGROUND Multi-phase computed tomography(CT)or magnetic resonance imaging(MRI)has been the standard of care for hepatocellular carcinoma(HCC)diagnosis for years.CASE SUMMARY We report a case series of four patients ...BACKGROUND Multi-phase computed tomography(CT)or magnetic resonance imaging(MRI)has been the standard of care for hepatocellular carcinoma(HCC)diagnosis for years.CASE SUMMARY We report a case series of four patients in whom positron emission tomographycomputed tomography(PET-CT)scan complemented the conventional CT/MRI scans in evaluating treatment response.In these four cases the conventional multi-phase CT and MRI failed to identify residual HCC disease post-treatment,while PET-CT complemented and aided in treatment response evaluation.In each case,the addition of PET-CT identified and located residual HCC disease,allowed retreatment,and altered medical management.CONCLUSION This case series suggests that PET-CT should perhaps play a role in the HCC management algorithm,in addition to the conventional contrast-enhanced multiphase scans.展开更多
BACKGROUND Primary aortoduodenal fistula is a rare cause of gastrointestinal(GI)bleeding consisting of abnormal channels between the aorta and GI tract without previous vascular intervention that results in massive in...BACKGROUND Primary aortoduodenal fistula is a rare cause of gastrointestinal(GI)bleeding consisting of abnormal channels between the aorta and GI tract without previous vascular intervention that results in massive intraluminal hemorrhage.CASE SUMMARY A 67-year-old man was hospitalized for coffee ground vomiting,tarry stools,and colic abdominal pain.He was repeatedly admitted for active GI bleeding and hypovolemic shock.Intermittent and spontaneously stopped bleeders were undetectable on multiple GI endoscopy,angiography,computed tomography angiography(CTA),capsule endoscopy,and ^(99)mTc-labeled red blood cell(RBC)scans.The patient received supportive treatment and was discharged without signs of rebleeding.Thereafter,he was re-admitted for bleeder identification.Repeated CTA after a bleed revealed a small aortic aneurysm at the renal level contacting the fourth portion of the duodenum.A ^(99)mTc-labeled RBC singlephoton emission CT(SPECT)/CT scan performed during bleeding symptoms revealed active bleeding at the duodenal level.According to his clinical symptoms(intermittent massive GI bleeding with hypovolemic shock,dizziness,dark red stool,and bloody vomitus)and the abdominal CTA and ^(99)mTc-labeled RBC SPECT/CT results,we suspected a small aneurysm and an aortoduodenal fistula.Subsequent duodenal excision and duodenojejunal anastomosis were performed.A 7-mm saccular aneurysm arising from the anterior wall of the abdominal aorta near the left renal artery was identified.Percutaneous intravascular stenting of the abdominal aorta was performed and his symptoms improved.CONCLUSION Our findings suggest that ^(99)mTc-labeled RBC SPECT/CT scanning can aid the diagnosis of a rare cause of active GI bleeding.展开更多
The plasmon-enhanced light emission of rutile TiO2(110) surface has been investigated by a low-temperature scanning tunneling microscope (STM). We found that the photon emission arises from the inelastic electron ...The plasmon-enhanced light emission of rutile TiO2(110) surface has been investigated by a low-temperature scanning tunneling microscope (STM). We found that the photon emission arises from the inelastic electron tunneling between the STM tip and the conduction band or defect states of TiO2(110). In contrast to the Au(111) surface, the maximum photon energy as a function of the bias voltage clearly deviates from the linear scaling behavior, suggesting the non-negligible effect of the STM tip on the band structure of TiO2. By performing differential conductance (dl/dV) measurements, it was revealed that such a deviation is not related to the tip-induced band bending, but is attributed to the image charge effect of the metal tip, which significantly shifts the band edges of the TiO2(110) towards the Femi level (EF) during the tunneling process. This work not only sheds new lights onto the understanding of plasmon-enhanced light emission of semiconductor surfaces, but also opens up a new avenue for engineering the plasmon-mediated interfacial charge transfer in molecular and semiconducting materials.展开更多
A scanning electron probe is used to study the secondary emission properties of the im-pregnated barium scandate dispenser cathode, the influence of the activation on the secondary emis-sion property, the secondary em...A scanning electron probe is used to study the secondary emission properties of the im-pregnated barium scandate dispenser cathode, the influence of the activation on the secondary emis-sion property, the secondary emission image and the secondary emission distribution over the surfaceof the cathode. At optimal activation, δ<sub>m</sub>=3.56 (E<sub>pm</sub>=700eV). The activation has a larger effect onδ when the activation temperature is higher than 1100℃. The distribution over the surface of thecathode is non-uniform. The half-peak width of the distribution curve over the surface is 0.4. Theexperimental phenomena are discussed in relation to surface analysis of the cathode. The theoreticallyderived binomial distribution curves over the surface fit much better with the experimental results.展开更多
Reaction dynamics in gases at operating temperatures at the atomic level are the basis of heterogeneous gas-solid catalyst reactions and are crucial to the catalyst function.Supported noble metal nanocatalysts such as...Reaction dynamics in gases at operating temperatures at the atomic level are the basis of heterogeneous gas-solid catalyst reactions and are crucial to the catalyst function.Supported noble metal nanocatalysts such as platinum are of interest in fuel cells and as diesel oxidation catalysts for pollution control,and practical ruthenium nanocatalysts are explored for ammonia synthesis.Graphite and graphitic carbons are of interest as supports for the nanocatalysts.Despite considerable literature on the catalytic processes on graphite and graphitic supports,reaction dynamics of the nanocatalysts on the supports in different reactive gas environments and operating temperatures at the single atom level are not well understood.Here we present real time in-situ observations and analyses of reaction dynamics of Pt in oxidation,and practical Ru nanocatalysts in ammonia synthesis,on graphite and related supports under controlled reaction environments using a novel in-situ environmental(scanning) transmission electron microscope with single atom resolution.By recording snapshots of the reaction dynamics,the behaviour of the catalysts is imaged.The images reveal single metal atoms,clusters of a few atoms on the graphitic supports and the support function.These all play key roles in the mobility,sintering and growth of the catalysts.The experimental findings provide new structural insights into atomic scale reaction dynamics,morphology and stability of the nanocatalysts.展开更多
Rock mass is fractured media. Its fracture is a nonlinear process. Theaccumulation of acoustic emission (AF) is closely related to the degree of damage. The dynamicsproblem is simply described based on the non-equilib...Rock mass is fractured media. Its fracture is a nonlinear process. Theaccumulation of acoustic emission (AF) is closely related to the degree of damage. The dynamicsproblem is simply described based on the non-equilibrium statistical theory of crack evolvement,trying to use the hybrid analysis of the statistical theory and scan electron microscopy (SEM), thecharacters of AE signals from rock damage in a mined-out area is synthetically analyzed andevaluated. These provide an evidence to reverse deduce and accurately infer the position of rockfracture for dynamical hazard control.展开更多
Halide perovskites are strategically important in the field of energy materials. Along with the rapid development of the materials and related devices, there is an urgent need to understand the structure–property rel...Halide perovskites are strategically important in the field of energy materials. Along with the rapid development of the materials and related devices, there is an urgent need to understand the structure–property relationship from nanoscale to atomic scale. Much effort has been made in the past few years to overcome the difficulty of imaging limited by electron dose,and to further extend the investigation towards operando conditions. This review is dedicated to recent studies of advanced transmission electron microscopy(TEM) characterizations for halide perovskites. The irradiation damage caused by the interaction of electron beams and perovskites under conventional imaging conditions are first summarized and discussed. Low-dose TEM is then discussed, including electron diffraction and emerging techniques for high-resolution TEM(HRTEM) imaging. Atomic-resolution imaging, defects identification and chemical mapping on halide perovskites are reviewed. Cryo-TEM for halide perovskites is discussed, since it can readily suppress irradiation damage and has been rapidly developed in the past few years. Finally, the applications of in-situ TEM in the degradation study of perovskites under environmental conditions such as heating,biasing, light illumination and humidity are reviewed. More applications of emerging TEM characterizations are foreseen in the coming future, unveiling the structural origin of halide perovskite’s unique properties and degradation mechanism under operando conditions, so to assist the design of a more efficient and robust energy material.展开更多
The transmission-line-circuit model of the Z accelerator, developed originally by W. A. STYGAR, P. A. CORCORAN, et al., is revised. The revised model uses different calculations for the electron loss and flow impedanc...The transmission-line-circuit model of the Z accelerator, developed originally by W. A. STYGAR, P. A. CORCORAN, et al., is revised. The revised model uses different calculations for the electron loss and flow impedance in the magnetically insulated transmission line system of the Z accelerator before and after magnetic insulation is established. By including electron pressure and zero electric field at the cathode, a closed set of equations is obtained at each time step, and dynamic shunt resistance (used to represent any electron loss to the anode) and flow impedance are solved, which have been incorporated into the transmission line code for simulations of the vacuum section in the Z accelerator. Finally, the results are discussed in comparison with earlier findings to show the effectiveness and limitations of the model.展开更多
AIM To investigate rates of distant metastases(DM) detected with [18]fluorodeoxyglucose-positron emissiontomography/computed tomography(^(18)FDG-PET/CT) in early stage invasive breast cancer.METHODS We searched the En...AIM To investigate rates of distant metastases(DM) detected with [18]fluorodeoxyglucose-positron emissiontomography/computed tomography(^(18)FDG-PET/CT) in early stage invasive breast cancer.METHODS We searched the English language literature databases of PubM ed, EMBASE, ISI Web of Knowledge, Web of Science and Google Scholar, for publications on DM detected in patients who had ^(18)FDG-PET/CT scans as part of the staging for early stages of breast cancer(stage Ⅰ?and Ⅱ), prior to or immediately following surgery. Reports published between 2011 and 2017 were considered. The systematic review was conducted according to the PRISMA guidelines.RESULTS Among the 18 total studies included in the analysis, the risk of DM ranged from 0% to 8.3% and 0% to 12.9% for stage Ⅰ?and Ⅱ invasive breast cancer, respectively. Among the patients with clinical stage Ⅱ, the rate of occult metastases diagnosed by ^(18)FDG-PET/CT was 7.2%(range, 0%-19.6%) for stage ⅡA and 15.8%(range, 0%-40.8%) for stage ⅡB. In young patients(< 40-yearold), ^(18)FDG-PET/CT demonstrated a higher prevalence of DM at the time of diagnosis for those with aggressive histology(i.e., triple-negative receptors and poorly differentiated grade).CONCLUSION Young patients with poorly differentiated tumors and stage ⅡB triple-negative breast cancer may benefit from ^(18)FDG-PET/CT at initial staging to detect occult DM prior to surgery.展开更多
We investigated the photon emission spectra on Ag(111)surface excited by tunneling electrons using a low temperature scanning tunneling microscope in ultrahigh vacuum.Characteristic plasmon modes were illustrated as a...We investigated the photon emission spectra on Ag(111)surface excited by tunneling electrons using a low temperature scanning tunneling microscope in ultrahigh vacuum.Characteristic plasmon modes were illustrated as a function of the bias voltage.The one electron excitation process was revealed by the linear relationship between the luminescence intensity and the tunneling current.Luminescence enhancement is observed in the tunneling regime for the relatively high bias voltages,as well as at the field emission resonance with bias voltage increased up to 9 V.Presence of a silver(Ag)nanoparticle in the tunneling junction results in an abnormally strong photon emission at the high field emission resonances,which is explained by the further enhancement due to coupling between the localized surface plasmon and the vacuum.The results are of potential value for applications where ultimate enhancement of photon emission is desired.展开更多
The secondary electron emission yields of materials depend on the geometries of their surface structures.In this paper,a method of depositing vertical graphene nanosheet(VGN)on the surface of the material is proposed,...The secondary electron emission yields of materials depend on the geometries of their surface structures.In this paper,a method of depositing vertical graphene nanosheet(VGN)on the surface of the material is proposed,and the secondary electron emission(SEE)characteristics for the VGN structure are studied.The COMSOL simulation and the scanning electron microscope(SEM)image analysis are carried out to study the secondary electron yield(SEY).The effect of aspect ratio and packing density of VGN on SEY under normal incident condition are studied.The results show that the VGN structure has a good effect on suppressing SEE.展开更多
An experimental study of the nonlinear changes in refractive index and transmission coefficient of single-crystal ZnSe:Fe2+, fabricated through the Fe-diffusion method, at long-pulse (~300 ns), sub-mJ, 2.94-mm Z-scan ...An experimental study of the nonlinear changes in refractive index and transmission coefficient of single-crystal ZnSe:Fe2+, fabricated through the Fe-diffusion method, at long-pulse (~300 ns), sub-mJ, 2.94-mm Z-scan probing is reported. As well, a theoretical model based on the generalized Avizonis-Grotbeck equations is developed and applied for straightforward fitting of the open- and closed-aperture Z-scans, obtained for ZnSe:Fe2+ with different Fe2+ centers concentrations. The modeling results reveal that the contributions in the absorption and refractive index nonlinearities of ZnSe:Fe2+ are “common” resonant-absorption saturation (the minor part) and pulse-induced heating of the samples (the major part), which are strongly dependent on Fe2+ concentrations. Large values of the index change (>~10-3) and partial resonant-absorption bleaching (limited by ~50%), both produced via the thermal effect mainly, are the features of the ZnSe:Fe2+ samples inherent to this type of excitation.展开更多
基金supported by the Natural Science Foundation of Henan Province(No.222300420596)China Railway Science and Technology Innovation Program Funded Project(CZ02-Special-03)Science and Technology Innovation Project funded by China Railway Tunnel Group(Tunnel Research 2021-03)。
文摘Acoustic emission(AE)source localization is a fundamental element of rock fracture damage imaging.To improve the efficiency and accuracy of AE source localization,this paper proposes a joint method comprising a three-dimensional(3D)AE source localization simplex method and grid search scanning.Using the concept of the geometry of simplexes,tetrahedral iterations were first conducted to narrow down the suspected source region.This is followed by a process of meshing the region and node searching to scan for optimal solutions,until the source location is determined.The resulting algorithm was tested using the artificial excitation source localization and uniaxial compression tests,after which the localization results were compared with the simplex and exhaustive methods.The results revealed that the localization obtained using the proposed method is more stable and can be effectively avoided compared with the simplex localization method.Furthermore,compared with the global scanning method,the proposed method is more efficient,with an average time of 10%–20%of the global scanning localization algorithm.Thus,the proposed algorithm is of great significance for laboratory research focused on locating rupture damages sustained by large-sized rock masses or test blocks.
文摘Humpback whales are migratory, spending summers in cooler, high-latitude waters and mating and calving in tropical and subtropical waters in 14 identified district population segments. It may be possible that the coastal areas are infected with low pathogenic avian influenza (LPAI) during the release of infected humpback whale feces. Therefore, humpback whales can be an effective reservoir of the avian influenza virus (AIV) from the Poles to the Continents to spread AIV to coastal animals. Strong ultraviolet (UV) exposure amidst CO2 emission increase and minimal sunspot number might cause mutations of aquatic virus and humpback whale in the Antarctic and the Arctic. LPAI or highly pathogenic avian influenza (HPAI) is expressed in the Continents under appropriate environmental factors. Since penguins are birds while humpback whales are marine mammals, the humpback whales infected by the mutant virus might cause interspecies transmission to a new host with evolutionary changes. The migration pattern is seasonally similar between migratory bird and humpback whale except: 1) different species of bird versus whale, 2) different landing area of land versus coast, 3) similar infection means of bird feces versus humpback whale feces. The contribution of AIV transmission by whales was several times larger than that by migratory birds. Therefore, the routes of humpback whales should be considered to prevent AIV outbreaks in addition to the flyways of migratory birds. Humpback whale stranding (y) along the Atlantic Coast of the USA was correlated with CO2 emissions (x) to have y = 0.3515x + 18.595 (R2 = 0.4069) during 1992-2016 while y = 0.0652x + 4.5847, (R2 = 0.6128) during 2016-2018. AIV outbreak in 2010 (y) along the Atlantic Coast was also correlated with humpback whale stranding (2016-2018) (x) as y = 0.1387x + 6.8184 (R2 = 0.3966). Since AIV outbreak was linearly (R2 = 0.9967) correlated with the minimum sunspot number, it was postulated that the unusual mortality events of humpback whale stranding might be caused by an infected mutant virus in the Arctic. Consequently, the humpback whales were stranded along major CO2 producing Atlantic Coast States toward the winter habitat of the West Indies during the CO2 emissions and the minimal sunspot number with strong UV radiation. The stranded dead whales should be burned as soon as possible to prevent further deadly viral interspecies transmission of AIV by the coastal animals. Since CO2 emissions were increased in 2017 and the sunspot number was minimal at the end of 2018, serious numbers of whales are expected to be stranded at the Gulf of Maine, States of North Carolina, New York, and Virginia from November 2018 till April 2019. To save humpback whales from the unusual mortality event along the Atlantic Coast, the reduction of CO2 emissions is suggested by replacement of fossil fuels combustion plants with nuclear power plants along the Atlantic Coast of the USA.
基金supported by the National Natural Science Foundation of China(No.U19A2086)the fund of Science and Technology Bureau of LeShan City(No.22ZDYJ0015).
文摘Tomographic gamma scanner(TGS),an advancedγ-ray nondestructive analysis technique,can locate and analyze nuclides in radioactive nuclear waste,and TGS can be categorized into two processes:e.g.,transmission measurement and emission measurement.Specifically,transmission measurements provide the basis for accurate measurement of nonuniform radionuclide content in TGS scanning.The scan data were obtained using the Monte Carlo tool Geant4 simulation,and 25 voxels were divided into five lengths and five widths in a square barrel.In this study,an encoding cropping algorithm based on draped foot vector judgment was adopted to rapidly calculate the voxel trace matrix within a square bucket of nuclear waste,and the transmission images were reconstructed using ordered subset expectation maximization.The results indicated that the cropping speed of the improved coding algorithm was significantly higher than that of the original algorithm,and the relative mean deviation and root-mean-square error between the reconstructed attenuation coefficient and the reference standard value tended to decrease with an increase in the cropped line segments in the voxel;the Pearson correlation coefficient tended to converge to 1.0.The image quality evaluation parameters of the high media-density materials were better than those of the low media-density materials in the above three indexes.The reconstruction effect was relatively poor for more complex filling materials.When there were more than 10 cropped line segments in the voxel,the reconstruction data generally tended to be stable.The graphical trimming algorithm can rapidly calculate the trace matrix of the scanned voxels;it exhibits the advantages of speed and efficiency and can serve as a novel method to solve the trace matrix of TGS nuclear waste transmission scans.
基金Project supported by the Science Foundation of Shanghai Municipal Commission of Science and Technology (Grant Nos.055207041, 047062012)
文摘This paper presents a serial synchronous scanning mode in fiat panel display (FPD) by adding a latch buffer between the serializer and the driving buffer. Comparing with conventional techniques, the proposed structure can efficiently reduce the brightness loss and improve the transmission performance. Theoretical analysis and experimental results show that the ratio between the lightest weight display time and the relative transmission time is a tradeoff between brightness loss and transmission efficiency.
基金supported by the National Basic Research Program of China(Grant No.2014CB921002)the Strategic Priority Research Program of Chinese Academy of Sciences(Grant No.XDB07030200)the National Natural Science Foundation of China(Grant Nos.51522212,51421002,and 51672307)
文摘Scanning transmission electron microscopy(STEM) has been shown as powerful tools for material characterization,especially after the appearance of aberration-corrector which greatly enhances the resolution of STEM. High angle annular dark field(HAADF) and annular bright field(ABF) imaging of the aberration-corrected STEM are widely used due to their high-resolution capabilities and easily interpretable image contrasts. However, HAADF mode of the STEM is still limited in detecting light elements due to the weak electron-scattering power. ABF mode of the STEM could detect light and heavy elements simultaneously, providing unprecedented opportunities for probing unknown structures of materials. Atomiclevel structure investigation of materials has been achieved by means of these imaging modes, which is invaluable in many fields for either improving properties of materials or developing new materials. This paper aims to provide a introduction of HAADF and ABF imaging techniques and reviews their applications in characterization of cathode materials, study of electrochemical reaction mechanisms, and exploring the effective design of lithium-ion batteries(LIBs). The future prospects of the STEM are also discussed.
基金Thisworkwas supported by the Shanghai Science and Technology Committee(No.22dz1204700)the NationalKeyR&D Program of China(Nos.2020YFA0803800 and 2017YFE0132200)+2 种基金the National Natural Science Foundation of China(Nos.82072510,21907034,21788102,21525417,and 51620105009)the Natural Science Foundation of Guangdong Province(Nos.2019B030301003 and 2016A030312002)the Innovation and Technology Commission of Hong Kong(No.ITC-CNERC14S01).
文摘Existing technologies used to detect monosodium urate(MSU)crystals for gout diagnosis are not ideal due to their low sensitivity and complexity of operation.The purpose of this study was to explore whether aggregation-induced emission luminogens(AIEgens)can be used for highly specific imaging of MSU crystals to assist in the diagnosis of gout.First,we developed a series of luminogens(i.e.,tetraphenyl ethylene(TPE)-NH_(2),TPE-2NH_(2),TPE-4NH_(2),TPE-COOH,TPE-2COOH,TPE-4COOH,and TPE-Ketoalkyne),each of which was then evenly mixed with MSU crystals.Next,optimal fluorescence imaging of each of the luminogens was characterized by a confocal laser scanning microscope(CLSM).This approach was used for imaging standard samples of MSU,hydroxyapatite(HAP)crystals,and mixed samples with 1:1 mass ratio of MSU/HAP.We also imaged samples from mouse models of acute gouty arthritis,HAP deposition disease,and comorbidities of interest.Subsequently,CLSM imaging results were compared with those of compensated polarized light microscopy,and we assessed the biosafety of TPE-Ketoalkyne in the RAW264.7 cell line.Finally,CLSM time series and three-dimensional imaging were performed on MSU crystal samples from human gouty synovial fluid and tophi.As a promising candidate for MSU crystal labeling,TPE-Ketoalkyne was found to detect MSU crystals accurately and rapidly in standard samples,animal samples,and human samples,and could precisely distinguish gout from HAP deposition disease.This work demonstrates that TPE-Ketoalkyne is suitable for highly specific and timely imaging of MSU crystals in gouty arthritis and may facilitate future research on MSU crystal-related diseases.
文摘BACKGROUND Multi-phase computed tomography(CT)or magnetic resonance imaging(MRI)has been the standard of care for hepatocellular carcinoma(HCC)diagnosis for years.CASE SUMMARY We report a case series of four patients in whom positron emission tomographycomputed tomography(PET-CT)scan complemented the conventional CT/MRI scans in evaluating treatment response.In these four cases the conventional multi-phase CT and MRI failed to identify residual HCC disease post-treatment,while PET-CT complemented and aided in treatment response evaluation.In each case,the addition of PET-CT identified and located residual HCC disease,allowed retreatment,and altered medical management.CONCLUSION This case series suggests that PET-CT should perhaps play a role in the HCC management algorithm,in addition to the conventional contrast-enhanced multiphase scans.
文摘BACKGROUND Primary aortoduodenal fistula is a rare cause of gastrointestinal(GI)bleeding consisting of abnormal channels between the aorta and GI tract without previous vascular intervention that results in massive intraluminal hemorrhage.CASE SUMMARY A 67-year-old man was hospitalized for coffee ground vomiting,tarry stools,and colic abdominal pain.He was repeatedly admitted for active GI bleeding and hypovolemic shock.Intermittent and spontaneously stopped bleeders were undetectable on multiple GI endoscopy,angiography,computed tomography angiography(CTA),capsule endoscopy,and ^(99)mTc-labeled red blood cell(RBC)scans.The patient received supportive treatment and was discharged without signs of rebleeding.Thereafter,he was re-admitted for bleeder identification.Repeated CTA after a bleed revealed a small aortic aneurysm at the renal level contacting the fourth portion of the duodenum.A ^(99)mTc-labeled RBC singlephoton emission CT(SPECT)/CT scan performed during bleeding symptoms revealed active bleeding at the duodenal level.According to his clinical symptoms(intermittent massive GI bleeding with hypovolemic shock,dizziness,dark red stool,and bloody vomitus)and the abdominal CTA and ^(99)mTc-labeled RBC SPECT/CT results,we suspected a small aneurysm and an aortoduodenal fistula.Subsequent duodenal excision and duodenojejunal anastomosis were performed.A 7-mm saccular aneurysm arising from the anterior wall of the abdominal aorta near the left renal artery was identified.Percutaneous intravascular stenting of the abdominal aorta was performed and his symptoms improved.CONCLUSION Our findings suggest that ^(99)mTc-labeled RBC SPECT/CT scanning can aid the diagnosis of a rare cause of active GI bleeding.
基金Project supported by the National Key R&D Program of China(Grant Nos.2016YFA0300901 and 2017YFA0205003)the National Natural Science Foundation of China(Grant Nos.11634001 and 21725302)the Key Research Program of the Chinese Academy of Sciences(Grant No.XDPB08-1)
文摘The plasmon-enhanced light emission of rutile TiO2(110) surface has been investigated by a low-temperature scanning tunneling microscope (STM). We found that the photon emission arises from the inelastic electron tunneling between the STM tip and the conduction band or defect states of TiO2(110). In contrast to the Au(111) surface, the maximum photon energy as a function of the bias voltage clearly deviates from the linear scaling behavior, suggesting the non-negligible effect of the STM tip on the band structure of TiO2. By performing differential conductance (dl/dV) measurements, it was revealed that such a deviation is not related to the tip-induced band bending, but is attributed to the image charge effect of the metal tip, which significantly shifts the band edges of the TiO2(110) towards the Femi level (EF) during the tunneling process. This work not only sheds new lights onto the understanding of plasmon-enhanced light emission of semiconductor surfaces, but also opens up a new avenue for engineering the plasmon-mediated interfacial charge transfer in molecular and semiconducting materials.
文摘A scanning electron probe is used to study the secondary emission properties of the im-pregnated barium scandate dispenser cathode, the influence of the activation on the secondary emis-sion property, the secondary emission image and the secondary emission distribution over the surfaceof the cathode. At optimal activation, δ<sub>m</sub>=3.56 (E<sub>pm</sub>=700eV). The activation has a larger effect onδ when the activation temperature is higher than 1100℃. The distribution over the surface of thecathode is non-uniform. The half-peak width of the distribution curve over the surface is 0.4. Theexperimental phenomena are discussed in relation to surface analysis of the cathode. The theoreticallyderived binomial distribution curves over the surface fit much better with the experimental results.
基金the Engineering and Physical Science Research Council(EPSRC),U.K.for the award of a research grant EP/J0118058/1 and postdoctoral research assistantships(PDRAs) to M.R.W.and R.W.M.from the grant。
文摘Reaction dynamics in gases at operating temperatures at the atomic level are the basis of heterogeneous gas-solid catalyst reactions and are crucial to the catalyst function.Supported noble metal nanocatalysts such as platinum are of interest in fuel cells and as diesel oxidation catalysts for pollution control,and practical ruthenium nanocatalysts are explored for ammonia synthesis.Graphite and graphitic carbons are of interest as supports for the nanocatalysts.Despite considerable literature on the catalytic processes on graphite and graphitic supports,reaction dynamics of the nanocatalysts on the supports in different reactive gas environments and operating temperatures at the single atom level are not well understood.Here we present real time in-situ observations and analyses of reaction dynamics of Pt in oxidation,and practical Ru nanocatalysts in ammonia synthesis,on graphite and related supports under controlled reaction environments using a novel in-situ environmental(scanning) transmission electron microscope with single atom resolution.By recording snapshots of the reaction dynamics,the behaviour of the catalysts is imaged.The images reveal single metal atoms,clusters of a few atoms on the graphitic supports and the support function.These all play key roles in the mobility,sintering and growth of the catalysts.The experimental findings provide new structural insights into atomic scale reaction dynamics,morphology and stability of the nanocatalysts.
基金This work was financially supported by the Natural Science Foundation of Shannxi Province (No.2003E_213 )the Doctoral Foundation of the Ministry of Education of China (No.20020008021)the National Natural Science Foundation of China (No.50074002)
文摘Rock mass is fractured media. Its fracture is a nonlinear process. Theaccumulation of acoustic emission (AF) is closely related to the degree of damage. The dynamicsproblem is simply described based on the non-equilibrium statistical theory of crack evolvement,trying to use the hybrid analysis of the statistical theory and scan electron microscopy (SEM), thecharacters of AE signals from rock damage in a mined-out area is synthetically analyzed andevaluated. These provide an evidence to reverse deduce and accurately infer the position of rockfracture for dynamical hazard control.
基金the Beijing Municipal High Level Innovative Team Building Program (IDHT20190503)the National Natural Science Fund for Innovative Research Groups of China (51621003)the National Natural Science Foundation of China (12074017)。
文摘Halide perovskites are strategically important in the field of energy materials. Along with the rapid development of the materials and related devices, there is an urgent need to understand the structure–property relationship from nanoscale to atomic scale. Much effort has been made in the past few years to overcome the difficulty of imaging limited by electron dose,and to further extend the investigation towards operando conditions. This review is dedicated to recent studies of advanced transmission electron microscopy(TEM) characterizations for halide perovskites. The irradiation damage caused by the interaction of electron beams and perovskites under conventional imaging conditions are first summarized and discussed. Low-dose TEM is then discussed, including electron diffraction and emerging techniques for high-resolution TEM(HRTEM) imaging. Atomic-resolution imaging, defects identification and chemical mapping on halide perovskites are reviewed. Cryo-TEM for halide perovskites is discussed, since it can readily suppress irradiation damage and has been rapidly developed in the past few years. Finally, the applications of in-situ TEM in the degradation study of perovskites under environmental conditions such as heating,biasing, light illumination and humidity are reviewed. More applications of emerging TEM characterizations are foreseen in the coming future, unveiling the structural origin of halide perovskite’s unique properties and degradation mechanism under operando conditions, so to assist the design of a more efficient and robust energy material.
基金supported by National Natural Science Foundation of China (No. 50637010)
文摘The transmission-line-circuit model of the Z accelerator, developed originally by W. A. STYGAR, P. A. CORCORAN, et al., is revised. The revised model uses different calculations for the electron loss and flow impedance in the magnetically insulated transmission line system of the Z accelerator before and after magnetic insulation is established. By including electron pressure and zero electric field at the cathode, a closed set of equations is obtained at each time step, and dynamic shunt resistance (used to represent any electron loss to the anode) and flow impedance are solved, which have been incorporated into the transmission line code for simulations of the vacuum section in the Z accelerator. Finally, the results are discussed in comparison with earlier findings to show the effectiveness and limitations of the model.
文摘AIM To investigate rates of distant metastases(DM) detected with [18]fluorodeoxyglucose-positron emissiontomography/computed tomography(^(18)FDG-PET/CT) in early stage invasive breast cancer.METHODS We searched the English language literature databases of PubM ed, EMBASE, ISI Web of Knowledge, Web of Science and Google Scholar, for publications on DM detected in patients who had ^(18)FDG-PET/CT scans as part of the staging for early stages of breast cancer(stage Ⅰ?and Ⅱ), prior to or immediately following surgery. Reports published between 2011 and 2017 were considered. The systematic review was conducted according to the PRISMA guidelines.RESULTS Among the 18 total studies included in the analysis, the risk of DM ranged from 0% to 8.3% and 0% to 12.9% for stage Ⅰ?and Ⅱ invasive breast cancer, respectively. Among the patients with clinical stage Ⅱ, the rate of occult metastases diagnosed by ^(18)FDG-PET/CT was 7.2%(range, 0%-19.6%) for stage ⅡA and 15.8%(range, 0%-40.8%) for stage ⅡB. In young patients(< 40-yearold), ^(18)FDG-PET/CT demonstrated a higher prevalence of DM at the time of diagnosis for those with aggressive histology(i.e., triple-negative receptors and poorly differentiated grade).CONCLUSION Young patients with poorly differentiated tumors and stage ⅡB triple-negative breast cancer may benefit from ^(18)FDG-PET/CT at initial staging to detect occult DM prior to surgery.
基金Project supported by the National Natural Science Foundation of China(Grant Nos.21961142021,11774395,and 11727902)the Strategic Priority Research Program(B)of the Chinese Academy of Sciences(Grant No.XDB30201000)the Beijing Natural Science Foundation,China(Grant No.4181003)。
文摘We investigated the photon emission spectra on Ag(111)surface excited by tunneling electrons using a low temperature scanning tunneling microscope in ultrahigh vacuum.Characteristic plasmon modes were illustrated as a function of the bias voltage.The one electron excitation process was revealed by the linear relationship between the luminescence intensity and the tunneling current.Luminescence enhancement is observed in the tunneling regime for the relatively high bias voltages,as well as at the field emission resonance with bias voltage increased up to 9 V.Presence of a silver(Ag)nanoparticle in the tunneling junction results in an abnormally strong photon emission at the high field emission resonances,which is explained by the further enhancement due to coupling between the localized surface plasmon and the vacuum.The results are of potential value for applications where ultimate enhancement of photon emission is desired.
基金supported by the National Natural Science Foundation of China(Grant No.11975163)。
文摘The secondary electron emission yields of materials depend on the geometries of their surface structures.In this paper,a method of depositing vertical graphene nanosheet(VGN)on the surface of the material is proposed,and the secondary electron emission(SEE)characteristics for the VGN structure are studied.The COMSOL simulation and the scanning electron microscope(SEM)image analysis are carried out to study the secondary electron yield(SEY).The effect of aspect ratio and packing density of VGN on SEY under normal incident condition are studied.The results show that the VGN structure has a good effect on suppressing SEE.
文摘An experimental study of the nonlinear changes in refractive index and transmission coefficient of single-crystal ZnSe:Fe2+, fabricated through the Fe-diffusion method, at long-pulse (~300 ns), sub-mJ, 2.94-mm Z-scan probing is reported. As well, a theoretical model based on the generalized Avizonis-Grotbeck equations is developed and applied for straightforward fitting of the open- and closed-aperture Z-scans, obtained for ZnSe:Fe2+ with different Fe2+ centers concentrations. The modeling results reveal that the contributions in the absorption and refractive index nonlinearities of ZnSe:Fe2+ are “common” resonant-absorption saturation (the minor part) and pulse-induced heating of the samples (the major part), which are strongly dependent on Fe2+ concentrations. Large values of the index change (>~10-3) and partial resonant-absorption bleaching (limited by ~50%), both produced via the thermal effect mainly, are the features of the ZnSe:Fe2+ samples inherent to this type of excitation.