针对现有基于端到端方面的情感分析(E2E-ABSA)方法研究中没有充分利用文本信息的不足,提出了一种基于BERT与融合词性、句法信息(lexical and syntactic information,LSI)的模型LSI-BERT。使用BERT嵌入层和TFM特征提取器来提取语义信息,...针对现有基于端到端方面的情感分析(E2E-ABSA)方法研究中没有充分利用文本信息的不足,提出了一种基于BERT与融合词性、句法信息(lexical and syntactic information,LSI)的模型LSI-BERT。使用BERT嵌入层和TFM特征提取器来提取语义信息,并通过工业级自然语言处理工具SpaCy提取词性信息,引入两个权重因子α和β对语义与词性信息进行融合;采用图注意网络(graph attention networks,GAT)根据句法依存树生成的邻接矩阵进行句法依存信息的提取;利用双流注意力网络针对句法依存信息和融合了词性信息的文本信息进行融合,使这两种信息实现更好的交互。实验结果表明,模型在三个常用基准数据集上的性能优于当前代表模型。展开更多
In this paper, the complete noncompact Kahler manifolds satisfying the weighted Poincare inequality are considered and one nonparabolic end theorem which generalizes Munteanu＇s result is obtained.
Six grades of biopolymers formulated to have oil content of 40% (M1), 50% (M2), and 60% (M3) melon seed oil (MESO) and 40% (C1), 50% (C2), and 60% (C3) cottonseed oil (COSO) respectively, were prepared with phthalic a...Six grades of biopolymers formulated to have oil content of 40% (M1), 50% (M2), and 60% (M3) melon seed oil (MESO) and 40% (C1), 50% (C2), and 60% (C3) cottonseed oil (COSO) respectively, were prepared with phthalic anhydride, and glycerol using alcoholysis-polycondensation process. The extend of polycondensation was monitored by determining the acid value of aliquots of the reaction mixture at various intervals of time. Molecular weight averages and polydispersity index (PDI) of the finished alkyds were determined by Rast method and end-group analysis. Molecular weight averages and PDI vary with differences in oil length of the alkyds, with samples M2 and C2 respectively exhibiting the highest PDI. Molecular weight average obtained from end-group analysis and those determined by Rast method in brackets are 1338.92 (597.00), 982.33 (696.25), 1316.09 (754.03), and 1160.57 (448.13), 765.96 (583.57), 1049.92 (696.25) for samples M1, M2, M3 and C1, C2, C3 respectively. Number molecular weight averages calculated from end-group analysis are larger than those obtained by Rast method for both MESO and COSO alkyds and seem to grossly overestimate their molecular weights. The mode of variation of these properties indicates that the synthesis of MESO and COSO alkyds are complex. Correlation of PDI with the quality of the finished alkyds shows that the higher the PDI value the better the quality of the alkyd. Performance properties such as rate of drying, film hardness and resistance to chemicals were optimum at 50% oil length for both triglyceride oil alkyds.展开更多
AIM: To assess intravoxel incoherent motion diffusionweighted imaging(IVIM-DWI) for monitoring early efficacy of chemotherapy in a human gastric cancer mouse model.METHODS: IVIM-DWI was performed with 12 b-values(0-80...AIM: To assess intravoxel incoherent motion diffusionweighted imaging(IVIM-DWI) for monitoring early efficacy of chemotherapy in a human gastric cancer mouse model.METHODS: IVIM-DWI was performed with 12 b-values(0-800 s/mm2) in 25 human gastric cancer-bearing nude mice at baseline(day 0), and then they were randomly divided into control and 1-, 3-, 5- and 7-d treatment groups(n = 5 per group). The control group underwent longitudinal MRI scans at days 1, 3, 5 and 7, and the treatment groups underwent subsequent MRI scans after a specified 5-fluorouracil/calciumfolinate treatment. Together with tumor volumes(TV), the apparent diffusion coefficient(ADC) and IVIM parameters [true water molecular diffusion coefficient(D), perfusion fraction(f) and pseudo-related diffusion coefficient(D*)] were measured. The differences in those parameters from baseline to each measurement(ΔTV%, ΔADC%, ΔD%, Δf% and ΔD*%) were calculated. After image acquisition, tumor necrosis, microvessel density(MVD) and cellular apoptosis were evaluated by hematoxylin-eosin(HE), CD31 and terminal-deoxynucleotidyl transferase mediated nick end labeling(TUNEL) staining respectively, to confirm the imaging findings. Mann-Whitney test and Spearman's correlation coefficient analysis were performed.RESULTS: The observed relative volume increase(ΔTV%) in the treatment group were significantly smaller than those in the control group at day 5(ΔTV_(treatment)% = 19.63% ± 3.01% and ΔTVcontrol% = 83.60% ± 14.87%, P = 0.008) and day 7(ΔTV_(treatment)% = 29.07% ± 10.01% and ΔTV_(control)% = 177.06% ± 63.00%, P = 0.008). The difference in ΔTV% between the treatment and the control groups was not significant at days 1 and 3 after a short duration of treatment. Increases in ADC in the treatment group(ΔADC%_(treatment), median, 30.10% ± 18.32%, 36.11% ± 21.82%, 45.22% ± 24.36%) were significantly higher compared with the control group(ΔADC%_(control), median, 4.98% ± 3.39%, 6.26% ± 3.08%, 9.24% ± 6.33%) at days 3, 5 and 7(P = 0.008, P = 0.016, P = 0.008, respectively). Increases in D in the treatment group(ΔD%_(treatment), median 17.12% ± 8.20%, 24.16% ± 16.87%, 38.54% ± 19.36%) were higher than those in the control group(ΔD%_(control), median-0.13% ± 4.23%, 5.89% ± 4.56%, 5.54% ± 4.44%) at days 1, 3, and 5(P = 0.032, P = 0.008, P = 0.016, respectively). Relative changes in f were significantly lower in the treatment group compared with the control group at days 1, 3, 5 and 7 follow-up(median,-34.13% ± 16.61% vs 1.68% ± 3.40%, P = 0.016;-50.64% ± 6.82% vs 3.01% ± 6.50%, P = 0.008;-49.93% ± 6.05% vs 0.97% ± 4.38%, P = 0.008, and-46.22% ± 7.75% vs 8.14% ± 6.75%, P = 0.008, respectively). D* in the treatment group decreased significantly compared to those in the control group at all time points(median,-32.10% ± 12.22% vs 1.85% ± 5.54%, P = 0.008;-44.14% ± 14.83% vs 2.29% ± 10.38%, P = 0.008;-59.06% ± 19.10% vs 3.86% ± 5.10%, P = 0.008 and-47.20% ± 20.48% vs 7.13% ± 9.88%, P = 0.016, respectively). Furthermore, histopathologic findings showed positive correlations with ADC and D and tumor necrosis(r_s = 0.720, P < 0.001; r_s = 0.522, P = 0.007, respectively). The cellular apoptosis of the tumor also showed positive correlations with ADC and D(r_s = 0.626, P = 0.001; r_s = 0.542, P = 0.005, respectively). Perfusionrelated parameters(f and D*) were positively correlated to MVD(r_s = 0.618, P = 0.001; r_s = 0.538, P = 0.006, respectively), and negatively correlated to cellular apoptosis of the tumor(r_s =-0.550, P = 0.004; r_s =-0.692, P < 0.001, respectively).CONCLUSION: IVIM-DWI is potentially useful for predicting the early efficacy of chemotherapy in a human gastric cancer mouse model.展开更多
Some new concepts of effective incidence matrix,ascending order adjacency matrix andend-result vertex are introduced,and some improvements of the maximum weight matchingalgorithm are made.With this method a computer p...Some new concepts of effective incidence matrix,ascending order adjacency matrix andend-result vertex are introduced,and some improvements of the maximum weight matchingalgorithm are made.With this method a computer program in FORTRAN language is realized onthe computers FELIX C-512 and IBM-PC.Good results are obtained in practical operations.展开更多
基金The NSF(11101352) of ChinaNew Century Talent Project of Yangzhou University,Fund of Jiangsu University of Technology(KYY 13005)Qing Lan Project
文摘In this paper, the complete noncompact Kahler manifolds satisfying the weighted Poincare inequality are considered and one nonparabolic end theorem which generalizes Munteanu＇s result is obtained.
文摘Six grades of biopolymers formulated to have oil content of 40% (M1), 50% (M2), and 60% (M3) melon seed oil (MESO) and 40% (C1), 50% (C2), and 60% (C3) cottonseed oil (COSO) respectively, were prepared with phthalic anhydride, and glycerol using alcoholysis-polycondensation process. The extend of polycondensation was monitored by determining the acid value of aliquots of the reaction mixture at various intervals of time. Molecular weight averages and polydispersity index (PDI) of the finished alkyds were determined by Rast method and end-group analysis. Molecular weight averages and PDI vary with differences in oil length of the alkyds, with samples M2 and C2 respectively exhibiting the highest PDI. Molecular weight average obtained from end-group analysis and those determined by Rast method in brackets are 1338.92 (597.00), 982.33 (696.25), 1316.09 (754.03), and 1160.57 (448.13), 765.96 (583.57), 1049.92 (696.25) for samples M1, M2, M3 and C1, C2, C3 respectively. Number molecular weight averages calculated from end-group analysis are larger than those obtained by Rast method for both MESO and COSO alkyds and seem to grossly overestimate their molecular weights. The mode of variation of these properties indicates that the synthesis of MESO and COSO alkyds are complex. Correlation of PDI with the quality of the finished alkyds shows that the higher the PDI value the better the quality of the alkyd. Performance properties such as rate of drying, film hardness and resistance to chemicals were optimum at 50% oil length for both triglyceride oil alkyds.
基金Supported by National Research Foundation of South Korea,No.NRF-2013R1A1A2013878 and No.2015R1A2A2A01007827
文摘AIM: To assess intravoxel incoherent motion diffusionweighted imaging(IVIM-DWI) for monitoring early efficacy of chemotherapy in a human gastric cancer mouse model.METHODS: IVIM-DWI was performed with 12 b-values(0-800 s/mm2) in 25 human gastric cancer-bearing nude mice at baseline(day 0), and then they were randomly divided into control and 1-, 3-, 5- and 7-d treatment groups(n = 5 per group). The control group underwent longitudinal MRI scans at days 1, 3, 5 and 7, and the treatment groups underwent subsequent MRI scans after a specified 5-fluorouracil/calciumfolinate treatment. Together with tumor volumes(TV), the apparent diffusion coefficient(ADC) and IVIM parameters [true water molecular diffusion coefficient(D), perfusion fraction(f) and pseudo-related diffusion coefficient(D*)] were measured. The differences in those parameters from baseline to each measurement(ΔTV%, ΔADC%, ΔD%, Δf% and ΔD*%) were calculated. After image acquisition, tumor necrosis, microvessel density(MVD) and cellular apoptosis were evaluated by hematoxylin-eosin(HE), CD31 and terminal-deoxynucleotidyl transferase mediated nick end labeling(TUNEL) staining respectively, to confirm the imaging findings. Mann-Whitney test and Spearman's correlation coefficient analysis were performed.RESULTS: The observed relative volume increase(ΔTV%) in the treatment group were significantly smaller than those in the control group at day 5(ΔTV_(treatment)% = 19.63% ± 3.01% and ΔTVcontrol% = 83.60% ± 14.87%, P = 0.008) and day 7(ΔTV_(treatment)% = 29.07% ± 10.01% and ΔTV_(control)% = 177.06% ± 63.00%, P = 0.008). The difference in ΔTV% between the treatment and the control groups was not significant at days 1 and 3 after a short duration of treatment. Increases in ADC in the treatment group(ΔADC%_(treatment), median, 30.10% ± 18.32%, 36.11% ± 21.82%, 45.22% ± 24.36%) were significantly higher compared with the control group(ΔADC%_(control), median, 4.98% ± 3.39%, 6.26% ± 3.08%, 9.24% ± 6.33%) at days 3, 5 and 7(P = 0.008, P = 0.016, P = 0.008, respectively). Increases in D in the treatment group(ΔD%_(treatment), median 17.12% ± 8.20%, 24.16% ± 16.87%, 38.54% ± 19.36%) were higher than those in the control group(ΔD%_(control), median-0.13% ± 4.23%, 5.89% ± 4.56%, 5.54% ± 4.44%) at days 1, 3, and 5(P = 0.032, P = 0.008, P = 0.016, respectively). Relative changes in f were significantly lower in the treatment group compared with the control group at days 1, 3, 5 and 7 follow-up(median,-34.13% ± 16.61% vs 1.68% ± 3.40%, P = 0.016;-50.64% ± 6.82% vs 3.01% ± 6.50%, P = 0.008;-49.93% ± 6.05% vs 0.97% ± 4.38%, P = 0.008, and-46.22% ± 7.75% vs 8.14% ± 6.75%, P = 0.008, respectively). D* in the treatment group decreased significantly compared to those in the control group at all time points(median,-32.10% ± 12.22% vs 1.85% ± 5.54%, P = 0.008;-44.14% ± 14.83% vs 2.29% ± 10.38%, P = 0.008;-59.06% ± 19.10% vs 3.86% ± 5.10%, P = 0.008 and-47.20% ± 20.48% vs 7.13% ± 9.88%, P = 0.016, respectively). Furthermore, histopathologic findings showed positive correlations with ADC and D and tumor necrosis(r_s = 0.720, P < 0.001; r_s = 0.522, P = 0.007, respectively). The cellular apoptosis of the tumor also showed positive correlations with ADC and D(r_s = 0.626, P = 0.001; r_s = 0.542, P = 0.005, respectively). Perfusionrelated parameters(f and D*) were positively correlated to MVD(r_s = 0.618, P = 0.001; r_s = 0.538, P = 0.006, respectively), and negatively correlated to cellular apoptosis of the tumor(r_s =-0.550, P = 0.004; r_s =-0.692, P < 0.001, respectively).CONCLUSION: IVIM-DWI is potentially useful for predicting the early efficacy of chemotherapy in a human gastric cancer mouse model.
文摘Some new concepts of effective incidence matrix,ascending order adjacency matrix andend-result vertex are introduced,and some improvements of the maximum weight matchingalgorithm are made.With this method a computer program in FORTRAN language is realized onthe computers FELIX C-512 and IBM-PC.Good results are obtained in practical operations.
