An age-structured SEIR epidemic model of a vertically as well as horizontally transmitted disease is investigated. Threshold results for the existence of endemic states are established for most cases. Under certain co...An age-structured SEIR epidemic model of a vertically as well as horizontally transmitted disease is investigated. Threshold results for the existence of endemic states are established for most cases. Under certain conditions, uniqueness is also shown. Threshold used are explicitly computable in term of demographic and epiderniological parameters of the model.展开更多
The dynamics of a single strain HIV model is studied. The basic reproduction number R0 used as a bifurcation parameter shows that the system undergoes transcritical and saddle-node bifurcations. The usual threshold un...The dynamics of a single strain HIV model is studied. The basic reproduction number R0 used as a bifurcation parameter shows that the system undergoes transcritical and saddle-node bifurcations. The usual threshold unit value of R0 does not completely determine the eradication of the disease in an HIV infected person. In particular, a sub-threshold value Rc is established which determines the system's number of endemic states: multiple if Rc 〈 Ro 〈 1, only one if Rc=Ro = 1, and none if R0 〈 Rc 〈 1.展开更多
The existence and uniqueness of positive steady states for the age-structured MSEIR epidemic model with age-dependent transmission coefficient is considered. Threshold results for the existence of endemic states are e...The existence and uniqueness of positive steady states for the age-structured MSEIR epidemic model with age-dependent transmission coefficient is considered. Threshold results for the existence of endemic states are established; under certain conditions, uniqueness is also shown.展开更多
A family of deterministic SEIRS epidemic dynamic models for malaria is presented. The family type is determined by a general functional response for the nonlinear incidence rate of the disease. Furthermore, the malari...A family of deterministic SEIRS epidemic dynamic models for malaria is presented. The family type is determined by a general functional response for the nonlinear incidence rate of the disease. Furthermore, the malaria models exhibit three random delays -- the incubation periods of the plasmodium inside the female mosquito and human hosts, and also the period of effective acquired natural immunity against the disease. Insights about the effects of the delays and the nonlinear incidence rate of the disease on (1) eradication and (2) persistence of malaria in the human population are obtained via analyzing and interpreting the global asymptotic stability results of the disease-free and endemic equilibrium of the system. The basic reproduction numbers and other threshold values for malaria are calculated, and superior threshold conditions for the stability of the equilibria are found. Numerical simulation results are presented.展开更多
基金Supported by the Natural Science Foundation of Henan Province(No.0312002000 and No.0211044800)the National Natural Science Foundation of China(No.10371105).
文摘An age-structured SEIR epidemic model of a vertically as well as horizontally transmitted disease is investigated. Threshold results for the existence of endemic states are established for most cases. Under certain conditions, uniqueness is also shown. Threshold used are explicitly computable in term of demographic and epiderniological parameters of the model.
文摘The dynamics of a single strain HIV model is studied. The basic reproduction number R0 used as a bifurcation parameter shows that the system undergoes transcritical and saddle-node bifurcations. The usual threshold unit value of R0 does not completely determine the eradication of the disease in an HIV infected person. In particular, a sub-threshold value Rc is established which determines the system's number of endemic states: multiple if Rc 〈 Ro 〈 1, only one if Rc=Ro = 1, and none if R0 〈 Rc 〈 1.
基金the Natural Science Foundation of Henan Province (No.994051200).
文摘The existence and uniqueness of positive steady states for the age-structured MSEIR epidemic model with age-dependent transmission coefficient is considered. Threshold results for the existence of endemic states are established; under certain conditions, uniqueness is also shown.
文摘A family of deterministic SEIRS epidemic dynamic models for malaria is presented. The family type is determined by a general functional response for the nonlinear incidence rate of the disease. Furthermore, the malaria models exhibit three random delays -- the incubation periods of the plasmodium inside the female mosquito and human hosts, and also the period of effective acquired natural immunity against the disease. Insights about the effects of the delays and the nonlinear incidence rate of the disease on (1) eradication and (2) persistence of malaria in the human population are obtained via analyzing and interpreting the global asymptotic stability results of the disease-free and endemic equilibrium of the system. The basic reproduction numbers and other threshold values for malaria are calculated, and superior threshold conditions for the stability of the equilibria are found. Numerical simulation results are presented.