Acute myocardial infarction (AMI) has been associated with poor prognosis,even after revascularization with percutaneous coronary intervention (PCI),likely due to coronary endothelial cell dysfunction and injury.^([1,...Acute myocardial infarction (AMI) has been associated with poor prognosis,even after revascularization with percutaneous coronary intervention (PCI),likely due to coronary endothelial cell dysfunction and injury.^([1,2])Endothelin-1 (ET-1),a peptide that serves as a vasoconstrictor of smooth muscle cell proliferation,can reflect endothelial cell functional states.Due to low circulation levels and short plasma half-life time,measuring plasma ET-1 levels is difficult.In contrast,big ET-1.展开更多
In the article titled“Astrocytic endothelin-1 overexpression impairs learning and memory ability in ischemic stroke via altered hippocampal neurogenesis and lipid metabolism,”published on pages 650-656,Issue 3,Volum...In the article titled“Astrocytic endothelin-1 overexpression impairs learning and memory ability in ischemic stroke via altered hippocampal neurogenesis and lipid metabolism,”published on pages 650-656,Issue 3,Volume 19 of Neural Regeneration Research(Li et al.,2024),there were two errors that needed to be corrected.展开更多
Objective To explore the influence of NO and serum endothelins change on prognosis of mixed type stroke patients. Method To test amount of ET and NO,to analysis the influence of NO and ET on prognosis using high effec...Objective To explore the influence of NO and serum endothelins change on prognosis of mixed type stroke patients. Method To test amount of ET and NO,to analysis the influence of NO and ET on prognosis using high effective liquid chromatography and radio immunology method and compared with the control group,then treat with t test. Result Concentrations of serum ET and NO of observe groups were apparently larger than that of control group (P<0.01, P<0.05). Conclusion Serum ET and NO increase apparently in mixed type stroke patients,the higher concentration, the severer disease and deformity of mobility.展开更多
基金National Clinical Research Center for Cardiovascular Diseases,Fuwai Hospital,Chinese Academy of Medical Sciences(NCRC2020013)CAMS Innovation Fund for Medical Sciences(2020-I2M-C&T-B-049)。
文摘Acute myocardial infarction (AMI) has been associated with poor prognosis,even after revascularization with percutaneous coronary intervention (PCI),likely due to coronary endothelial cell dysfunction and injury.^([1,2])Endothelin-1 (ET-1),a peptide that serves as a vasoconstrictor of smooth muscle cell proliferation,can reflect endothelial cell functional states.Due to low circulation levels and short plasma half-life time,measuring plasma ET-1 levels is difficult.In contrast,big ET-1.
文摘In the article titled“Astrocytic endothelin-1 overexpression impairs learning and memory ability in ischemic stroke via altered hippocampal neurogenesis and lipid metabolism,”published on pages 650-656,Issue 3,Volume 19 of Neural Regeneration Research(Li et al.,2024),there were two errors that needed to be corrected.
文摘Objective To explore the influence of NO and serum endothelins change on prognosis of mixed type stroke patients. Method To test amount of ET and NO,to analysis the influence of NO and ET on prognosis using high effective liquid chromatography and radio immunology method and compared with the control group,then treat with t test. Result Concentrations of serum ET and NO of observe groups were apparently larger than that of control group (P<0.01, P<0.05). Conclusion Serum ET and NO increase apparently in mixed type stroke patients,the higher concentration, the severer disease and deformity of mobility.
