GENE ENGINEERING EB VIRUS MEMBRANE ANTIGEN IN DETECTION OF MA-IgA ANTIBODY(COMPARISON WITH VCA-IgA AND EA-IgA ANTIBODIES)

With gene engineering EB virus membrane antigen as the diagnostic antigen, indirect immunofluo-rescence (IF) assay was used to detect IgA antibody against EB virus membrane antigen (MA-IgA) in sera from 202 nasopharyngeal carcinoma (NPC) patients and 315 controls (normal and patients with other tumors). MA-IgA antibody was positive in 96.8% of the pretreatment NPC patients with a GMT of 1:36.3. MA-IgA detection by this method was more sensitive than EA-IgA detection by IE. In contrast, patients with tumors other than NPC were negative for MA-IgA antibody. 9.1% of VCA-IgA positive persons were MA-IgA positive with a GMT of less than 1:5. No MA-IgA positive was found in VCA-IgA negatives. The results indicated that this method was relatively specific. In the treatment group, the positive rate and GMT of MA-IgA antibody declined with increase in survival time and the decline was faster than VCA-IgA. When recurrence or distant metastasis developed, similar to VCA-IgA and EA-IgA antibodies, the positive rate and GMT of MA-IgA antibody increased to its pretreatment level. Therefore, MA-IgA detection might be valuable in the early diagnosis and monitor of NPC.

Application Research of Sonar Detection Method in Melting Exploration at the Bottom of Piles

Karst landforms are widely distributed in China,and are most common in Yunnan,Guizhou and Guangxi.If the development of karst caves at the bottom of the piles cannot be accurately ascertained before the construction of bridge pile foundations,accidents such as hole collapse,slurry leakage,and drill sticking will easily occur.In this paper,the principle and method of sonar detection for detecting karst caves at the bottom of bridge piles was introduced,and the sonar detection data and the cave situation at the bottom of the pile during the construction process in combination with the case of Yunnan Zhenguo Highway Project was analyzed,which verifies the practicability and reliability of sonar detection method reliability.

Design of comprehensive test system for detecting overlying strata mining-induced fractures on surface with radon gas

Based on radon gas properties and its existing projects applications, we firstly attempted to apply geo- physical and chemical properties of radon gas in the field of mining engineering, and imported radioac- tive measurement method to detect the development process of the overlying strata mining-induced fractures and their contained water quality in underground coal mining, which not only innovates a more simple-fast-reliable detection method, but also further expands the applications of radon gas detection technology in mining field. A 3D simulation design of comprehensive testing system for detecting strata mining-induced fractures on surface with radon gas (CTSR) was carried out by using a large-scale 3D solid model design software Pro/Engineer (Pro/E), which overcame three main disadvantages of ''static design thought, 2D planar design and heavy workload for remodification design'' on exiting design for mining engineering test systems. Meanwhile, based on the simulation design results of Pro/E software, the sta- bility of the jack-screw pressure bar for the key component in CTSR was checked with a material mechan- ics theory, which provided a reliable basis for materials selection during the latter machining process.