Comparative analysis of breast and lung cancer survival rates and clinical trial enrollments among rural and urban patients in Georgia

Objectives:Rural patients have poor cancer outcomes and clinical trial(CT)enrollment compared to urban patients due to attitudinal,awareness,and healthcare access differential.Knowledge of cancer survival disparities and CT enrollment is important for designing interventions and innovative approaches to address the stated barriers.The study explores the potential disparities in cancer survival rates and clinical trial enrollments in rural and urban breast and lung cancer patients.Our hypotheses are that for both cancer types,urban cancer patients will have longer 5-year survival rates and higher enrollment rates in clinical trials than those in rural counties.Methods:We compared breast and lung cancer patients’survival rates and enrollment ratios in clinical trials between rural(RUCC 4-9)and urban counties in Georgia at a Comprehensive Cancer Center(CCC).To assess these differences,we carried out a series of independent samples t-tests and Chi-Square tests.Results:The outcomes indicate comparable 5-year survival rates across rural and urban counties for breast and lung cancer patients,failing to substantiate our hypothesis.While clinical trial enrollment rates demonstrated a significant difference between breast and lung cancer patients at CCC,no significant variation was observed based on rural or urban classification.Conclusion:These findings underscore the need for further research into the representation of rural patients with diverse cancer types at CCC and other cancer centers.Further,the findings have considerable implications for the initiation of positive social change to improve CT participation and reduce cancer survival disparities.

The Impact of Demographics and Cultural Tourism on University Enrollments in Calabria, Italy

The decline in the birth rate,which has been uninterrupted in Italy since the mid-1960s,has had a significant impact on many aspects of society.As far as the educational system is concerned,this phenomenon has acted like a wave,first causing a decline in the population of the first school age groups,then in the other groups,until recently affecting the 19-25 age group,which includes the majority of university students.As a result,the majority of Italian universities have seen a decline over time in both enrollments(matriculations)and student numbers(enrollments),although the situation varies from one area to another.In the Mezzogiorno,this trend is even more pronounced,since an increasing number of resident students tend to favor universities in the Centre-North,creating a South-Centre-North movement,which could be compared to a particular form of cultural tourism,without a similar flow in the opposite direction.Finally,the study highlights the probable consequences of the recent demographic depopulation on the future trend of university enrollment of residents aged 19-25 in the Calabria region,using the most recent demographic projections of Istat and constructing two evolutionary scenarios.In the first scenario,we have assumed that in the near future university enrollment rates remain constant throughout the period considered;in the second scenario,these rates instead experience a gradual and continuous increase.These results could be useful if further forecasts of university enrollments were to be made at the level of individual Calabrian universities.

Reform and Implementation of Teaching Management for Medical Graduate Students

With the expansion of medical graduate enrollment, there are some problems in graduate teaching management, such as shortage of faculty, insufficient funding, and single assessment management. This can be solved by improving the quality of enrollment, strengthening process management and quality monitoring, enhancing the quality of mentors, and building a management team. This provides theoretical support and practical guidance for the management of graduate education in medical colleges, which helps to improve the quality of graduate education and cultivate more high-quality medical talents for the national healthcare industry.

Research on Quality Assurance System of Talent Cultivation in Higher Vocational Colleges from the Background of Enrollment Expansion

The enrollment expansion of higher vocational education is not only a strategic measure to alleviate the structural contradiction of employment,but also an important support for economic transformation and upgrading.How to deal with the expansion of enrollment and ensure the quality of training is an important task of higher vocational colleges at this stage.Based on the development requirements of the new era,it is of great practical significance to build a perfect quality assurance system of talent training.

Factors Influencing Students Decisions to Enrollment in Sudanese Higher Education Institutions

There is a growing body of literature that recognizes the importance of data mining in educational systems. This recognition makes educational data mining a new growing research community. One way to achieve the highest level of quality in a higher education system is by discovering knowledge from educational data such as students’ enrollment data. Many mining tools that aim to discover exciting correlations, frequent patterns, associations, or casual structures among sets of items in educational data sets have been proposed. One of the widely used tools is association rules. In this paper, the Apriori algorithm is used to generate association rules to discover the importance and correlation between factors that influence student’s decision to enroll in higher education institutions in Sudan. The algorithm is applied using a student’s enrollment data set that was created using a questionnaire and 800 students enrolled in governmental and private sector universities as a sample. This paper classifies factors that influence enrollment into: student’s demographic factors and four categories of enrollment related factors (Student and Society, Educational Institution, Admission, and Employment related factors), and determines the most influential factors in determining student’s decision to enroll in Sudanese universities. The analysis result shows that the Educational Institution related factors (50%) and Admission related factors (40%) are strongly influencing students’ enrollment decision, while the Employment related factors (10%) and Student and Society related factors (0%) have weak influence. The factors out of the 14 Educational Institution related factors that have a high impact are: reputation, diversity of study, quality of education, education facilities, and feasibility.

Feasibility Study of Enforcing Immunization Certificate Check Before Primary School or Kindergarten Enrollment in Guizhou Province, China

Objective To study the feasibility of enforcing immunization certificate check before children enroll in primary schools or kindergartens in Guizhou Province. Methods Quantitative and qualitative studies were conducted. The multi-stage and cluster sampling approach was adopted for the quantitative part of the study. A questionnaire was designed and 996 children and their keepers were interviewed. Principals, doctors or teachers of the primary schools, directors and child care nurses of kindergarten, and staff of immunization agencies were invited to take part in 12 focus group discussions; meanwhile, face-to-face individual in-depth interviews with 16 officials of the Health, Education and Governmental Departments at various levels were conducted. Results The total number of subjects was 996. 16.7% of the children in the study completed all the procedures of the National Immunization Programme. 34.3% of them had immunization certificates while the remainder 44.7% registered in immunization agencies. Factors, including the migrant children, doubt about vaccine efficiency, mother’s occupation and educational background, knowledge of the National Immunization Programme on targeted vaccines, played an important role in obtaining or not immunization certificates. 95% of the keepers interviewed thought the immunization certificates were useful; 94.8% of them considered the check was critical while only 3.6% of them thought it unnecessary. The first reason from those who found it unnecessary was that they feared that repeated immunization might affect their children’s health. The second reason was the cost of immunization, which some of them could not afford to pay. However, the Health Department expressed a favorable attitude to the checking scheme. Though the Education Department agreed that the scheme was essential, they worried that it would affect the enrollment rate.Conclusion In spite of the difficulty in administering immunization certificate check, the effort would be rewarding for raising the immunization coverage rate among the children in Guizhou Province.

Certification and Conversion Mode of Learning Achievement Based on Credit Bank under the Background of Higher Vocational Enrollment Expansion

Credit bank system is a very important management mode in current higher vocational education,and it is also an important means for the Ministry of Education to promote China's modern education reform.This paper combines the specific background of higher vocational enrollment expansion,expounds the practical significance of the credit bank system in the training of the expanded enrollment talents,and explores the methods and rules of the authentication and transformation of the learning achievement of the expanded enrollment students under the system.In order to achieve convergence of different types of learning results,smooth talent growth channel,a useful exploration is carried out.

Informed consent process: ethical and practical challenges in clinical trials regarding subject enrollment, protection, and informed consent in developing countries (India, Pakistan & Iran)

In this study,we are discussing the rationale behind informed consent in clinical trials in developing countries.It elaborates how informed consent has remained an ethical and practical issue.Poverty,endemic diseases,and a lack of investment in healthcare systems influence the ease of conducting and selecting trials that can benefit the people of developing countries.Differences in cultural perspectives,religious beliefs,a lack of formal training for clinical staff,children,time zone difference,literacy,vulnerable population,and language barriers for subject enrollment,protection,and informed are also challenges.This report doesn’t only highlight the right the wrongs of the past or reiterate cases where clinical trials have hurt subjects in developing countries.The current study investigates the conditions of human research in developing countries to make them more ethically sound.The extends proposals to investigators,scientists,governments,sponsors,and other groups who are interested where appropriate.

Research on Application of Self-media Platform in College Enrollment Publicity in the New Period

Since the arrival of the media era,colleges and universities have undergone many new changes in enrollment,especially in the recruitment publicity work,self-media platform plays an important role.But for now,there are some problems in the application of self-media in college enrollment propaganda,for example,the promotion and management level of the platform needs to be improved,and the low quality of platform push content seriously affects the application effect of self-media.This paper aims at the problems existing in the application of self-media platform in the college enrollment propaganda,and formulates the effective solution strategy of the department,constantly improve the application effect of self-media platform in college enrollment propaganda.

The plight and Countermeasures brought to the constructions of library literature by effect of college enrollment

This text introduces the concept of local literature and collection range, explains the significance of literature collection and explores building programs of local university library. Currently, university library generally put a strong emphasis on collection of academic literature, but has less attention on literature collections which reflect the situation of university location, or even worse, simply don＇ t launch business in this field. For the university library, it is a great loss of literature information resources, as well as a great regret of library work. First, what is the local literature？ It is literature data which document a region＇ s past and present issues like politics, economy, culture, education, history, geography and other aspects like important characters and events, customs, folklore etc.

Realistic Dilemma and Solution of “Vocational Skill Test” under the Background of Enrollment Reform of Classified Examination in Higher Vocational Colleges in Jilin Province

In the process of Higher Vocational classified examination enrollment reform,Jilin Province has adopted a diversified examination enrollment model and“cultural quality test+vocational skill test”evaluation method,and established the“vocational education college entrance examination”system.This paper analyzes the important role and practical difficulties of“vocational skill test”in Higher Vocational classified examination,studies the existing problems,and puts forward to reasonably divide the proportion of“cultural quality test”and“vocational skill test”,sets diversified admission standards,scientifically sets up the assessment methods and contents of“vocational skill test”,further improves the“cultural quality test+vocational skill test”evaluation method and builds a classified examination and enrollment system more in line with the characteristics of vocational education.

What Is the Impact of Major Diversion Attitude on Undergraduates' Learning Gains?--The Mediating Role of Course Perception

Major diversion is an important part of the large-category student enrollment and training model.The degree to which undergraduates recognize the logic of the major diversion system,their satisfaction with the diverted major,and their major identity after diversion all influence their subsequent learning process and outcomes.The questionnaire survey of undergraduates in this study discovered that major diversion attitude has a significant positive effect on undergraduates'learning gains;the mediating effect test discovered that course perception plays a partially mediating role between major diversion attitude and learning gains.Therefore,under the large-category student enrollment and training model,it is necessary to improve the major diversion system in terms of formulation,major selection guidance,and major identity promotion.Furthermore,strengthening the logical connection and content coupling of different types of courses,dealing with the proportion,priority,and sequence of courses,optimizing the allocation of course resources,and reasonably planning and setting courses all play an important role in improving undergraduate learning gains.

Establishing the Forecasting Model with Time Series Data Based on Graph and Particle Swarm Optimization

In recent years,a wide variety of fuzzy time series(FTS)forecasting models have been created and recommended to handle the complicated and ambiguous challenges relating to time series data from real-world sources.However,the accuracy of a model is problem-specific and varies across data sets.But a model’s precision varies between different data sets and depends on the situation at hand.Even though many models assert that they are better than statistics and a single machine learning-based model,increasing forecasting accuracy is still a challenging task.In the fuzzy time series models,the size of the intervals and the fuzzy relationship groups are thought to be crucial variables that affect the model’s forecasting abilities.This study offers a hybrid FTS forecasting model that makes use of both the graph-based clustering technique(GBC)and particle swarm optimization(PSO)for adjusting interval lengths in the universe of discourse(UoD).The suggested model’s forecasting results have been compared to those provided by other current models on a dataset of enrollments at the University of Alabama.For all orders of fuzzy relationships,the suggested model outperforms its counterparts in terms of forecasting accuracy.

Fuzzy Time Series Forecasting Based On K-Means Clustering

Many forecasting models based on the concepts of Fuzzy time series have been proposed in the past decades. These models have been widely applied to various problem domains, especially in dealing with forecasting problems in which historical data are linguistic values. In this paper, we present a new fuzzy time series forecasting model, which uses the historical data as the universe of discourse and uses the K-means clustering algorithm to cluster the universe of discourse, then adjust the clusters into intervals. The proposed method is applied for forecasting University enrollment of Alabama. It is shown that the proposed model achieves a significant improvement in forecasting accuracy as compared to other fuzzy time series forecasting models.

我国临床医学长学制博士生教育招生路径和培养模式比较

围绕建设中国特色高水平医学人才培养体系的关键问题,聚焦长学制临床医学博士生教育,比较分析临床医学八年一贯制、“4+4”模式、直博/硕博连读等长学制临床医学教育的不同招生路径和培养模式,提出创新发展临床医学博士生教育的若干政策建议。

Immediate and mid-term outcomes of drug-eluting stent in treatment of coronary artery stenosis with very long defuse lesions

Objectives To evaluate the feasibility, and immediate and mid-term outcomes of drug-eluting stents (DESs) in the treatment of coronary artery stenosis with very long defuse lesions(VLDL). Methods Inclusion criteria:

Awareness of non-alcoholic steatohepatitis and treatment guidelines:What are physicians telling us?

BACKGROUND There is an acute need to raise awareness of non-alcoholic fatty liver disease/nonalcoholic steatohepatitis(NAFLD/NASH)among primary care physicians,endocrinologists and diabetologists to improve patient identification and address the current difficulties in NASH clinical trial enrollment.We examined the extent of knowledge and practice regarding NASH diagnosis and management guidelines.A randomized online convenience survey of 12869 physicians drawn from a national physician database of primary care physicians(PCPs),and gastroenterology and endocrinology specialists were queried via online survey.Our results,based on a cohort of 185 respondents,showed gaps in knowledge and practice between these three groups of practitioners,with primary care providers having the lowest adherence to published guidelines for diagnosis of NASH.Without clear knowledge and patient identification at the point of presentation-which is often in primary care or with specialties other than hepatology–many patients with NAFLD and NASH will remain undiagnosed and untreated,and clinical studies will continue to struggle with patient recruitment,hindering clinical development and optimal patient care.AIM To determine knowledge base concerning NASH diagnosis amongst gastroenterologists,endocrinologists and primary care physicians to improve referrals into clinical trials.METHODS A randomized online convenience survey of 12869 physicians drawn from a national physician database of PCPs,and gastroenterology and endocrinology specialists was conducted yielding a sample of 185 respondents.RESULTS The survey revealed that many physicians are either unaware of testing options other than biopsy,or do not use them in practice.Only 46%of endocrinologists and 42%of primary care physicians indicated they would refer a patient for specialist workup if they suspected NASH.Risk(25%)and inconvenience to patients(18%)are given as reasons for not referring those with suspected NASH for biopsy.For standard diagnostic algorithms such as Fibrosis-4 score,18%of PCPs,30%of endocrinologists and 65%gastroenterologists reported using these tests in clinical practice.CONCLUSION Substantial gaps in knowledge of the differences between NAFLD and NASH exist between these physician groups,with knowledge being particularly low among primary care doctors and endocrinologists.The use of a simple noninvasive screening algorithm may help to identify the right patients for clinical trials,which in turn will be vital to the development of effective and welltolerated treatments for this increasingly ubiquitous condition.

The Role of Recruitment and Retention in Clinical Trials

It is evident that both recruitment and retention play critical roles in clinical trials. Recruitment and retention models are beginning to be analyzed worldwide in an effort to assess how to conduct studies more efficiently, all the while, allowing researchers to provide sound and ethical data to help advance medicine through clinical studies. Sponsors and sites have recognized that clinical trial enrollment must become more diverse and inclusive. In this review, we address the important topics of recruitment and retention in clinical trials. Specifically, the obstacles in regard to recruiting vulnerable populations. Methodologies to improve both the understanding of the study population and community engagement are outlined. In particular, newer strategies such as use of social media and more reliable strategies such as trust and relationship building are described in detail. A strong focus on recruitment is becoming widely recognized as being of such importance that consideration is given to this key component even during initial protocol development. Attention to recruitment and retention in the strategic planning process of clinical trials can mitigate enrollment issues that clinical researchers are experiencing.

Mobilization Initiatives for Enhancing Secondary School Students’ Enrolment into Vocational and Technical Education Program of Universities for Self Reliance in South East, Nigeria

This study focused on identification of mobilization initiatives for enhancing student’s enrolment into Vocational and Technical Education (VTE) programs in Nigerian Universities. Three research questions guided the study while three hypotheses were formulated and tested at 0.05 level of significance. The study was carried out in South East, Nigeria. Population for the study was 1340. Sample for the study was 753 obtained through proportionate (30%) stratified random sampling technique. A 38 item questionnaire was developed and used to collect data. Data obtained were analyzed using mean and standard deviation to answer research questions while t-test statistic was used to test hypotheses at probability of 0.05 level. It was found out by the study that 38 mobilization initiatives could be used to enhance students’ enrolment into Vocational and Technical Education Programs in Nigerian Universities. It was therefore recommended that the identified mobilization initiatives be implemented by relevant stakeholders to enhance secondary school students’ enrollment into VTE programs in Nigerian Universities.

Appeal of 3 ＋ 4 Program： Good Students are Few but Growing at Secondary Vocational Schools in Shanghai

Secondary vocational education in Shanghai continues to experiment in an attempt to find ways to solve the decline of student enrollment and adjust to rapidly changing social and economic environments. The 3 ＋ 4 Pilot Program （three-year secondary vocational education and four-year undergraduate education） has been under experiment since 2014. It has attracted more and more academically good junior middle school graduates to secondary vocational schools with the national and local favorable policies and laws. Except the three-year’s hand-on practice, what appeals most to the junior middle school graduates is the academic transfer under the Program, a breakthrough in history of vocation education in China. However, only initiating a new program is not enough. Shanghai government should map out a long-term plan to set up promotion to increase the public awareness to change the long prevailing outdated ideology in order to add more to its appeal of the Program. There is still much work to be done before expanding the scope of the Program.