In the context of economic globalization,while multinational enterprises from developed countries occupy a high-end position in the global value chain,enterprises from developing countries are often marginalized in th...In the context of economic globalization,while multinational enterprises from developed countries occupy a high-end position in the global value chain,enterprises from developing countries are often marginalized in the world market.In China,resource-based state-owned enterprises(SOEs)are tasked with the mission of safeguarding resource security,and their internationalization development ideas and strategic deployment are significantly and fundamentally different from those of other non-state-owned enterprises and large multinational corporations.This study provides ideas for the globalization policies of enterprises in developing countries.We consider J Group in western China as a case and discuss its productive investment and global production network development from 2010 to 2019.We found that J Group was‘Partly'globalized,and there are multiple core nodes with the characteristics of centralized and decentralized coexistence in the production network;in addition,the overall layout centre shifted to Southeast Asia and China;however,its global production was restricted by the enterprise's investment security considerations,support and restrictions of the home country,political security risk of the host country,and sanctions from the West.These findings provide insights for future research:under the wave of anti-globalization and'internal circulation as the main body',resource SOEs should consider the potential risk of investment,especially keeping the middle and downstream industrial chain in China as much as possible.展开更多
Medical procedures are inherently invasive and carry the risk of inducing pain to the mind and body.Recently,efforts have been made to alleviate the discomfort associated with invasive medical procedures through the u...Medical procedures are inherently invasive and carry the risk of inducing pain to the mind and body.Recently,efforts have been made to alleviate the discomfort associated with invasive medical procedures through the use of virtual reality(VR)technology.VR has been demonstrated to be an effective treatment for pain associated with medical procedures,as well as for chronic pain conditions for which no effective treatment has been established.The precise mechanism by which the diversion from reality facilitated by VR contributes to the diminution of pain and anxiety has yet to be elucidated.However,the provision of positive images through VR-based visual stimulation may enhance the functionality of brain networks.The salience network is diminished,while the default mode network is enhanced.Additionally,the medial prefrontal cortex may establish a stronger connection with the default mode network,which could result in a reduction of pain and anxiety.Further research into the potential of VR technology to alleviate pain could lead to a reduction in the number of individuals who overdose on painkillers and contribute to positive change in the medical field.展开更多
BACKGROUND Mitochondrial genes are involved in tumor metabolism in ovarian cancer(OC)and affect immune cell infiltration and treatment responses.AIM To predict prognosis and immunotherapy response in patients diagnose...BACKGROUND Mitochondrial genes are involved in tumor metabolism in ovarian cancer(OC)and affect immune cell infiltration and treatment responses.AIM To predict prognosis and immunotherapy response in patients diagnosed with OC using mitochondrial genes and neural networks.METHODS Prognosis,immunotherapy efficacy,and next-generation sequencing data of patients with OC were downloaded from The Cancer Genome Atlas and Gene Expression Omnibus.Mitochondrial genes were sourced from the MitoCarta3.0 database.The discovery cohort for model construction was created from 70% of the patients,whereas the remaining 30% constituted the validation cohort.Using the expression of mitochondrial genes as the predictor variable and based on neural network algorithm,the overall survival time and immunotherapy efficacy(complete or partial response)of patients were predicted.RESULTS In total,375 patients with OC were included to construct the prognostic model,and 26 patients were included to construct the immune efficacy model.The average area under the receiver operating characteristic curve of the prognostic model was 0.7268[95% confidence interval(CI):0.7258-0.7278]in the discovery cohort and 0.6475(95%CI:0.6466-0.6484)in the validation cohort.The average area under the receiver operating characteristic curve of the immunotherapy efficacy model was 0.9444(95%CI:0.8333-1.0000)in the discovery cohort and 0.9167(95%CI:0.6667-1.0000)in the validation cohort.CONCLUSION The application of mitochondrial genes and neural networks has the potential to predict prognosis and immunotherapy response in patients with OC,providing valuable insights into personalized treatment strategies.展开更多
Distinct brain remodeling has been found after different nerve reconstruction strategies,including motor representation of the affected limb.However,differences among reconstruction strategies at the brain network lev...Distinct brain remodeling has been found after different nerve reconstruction strategies,including motor representation of the affected limb.However,differences among reconstruction strategies at the brain network level have not been elucidated.This study aimed to explore intranetwork changes related to altered peripheral neural pathways after different nerve reconstruction surgeries,including nerve repair,endto-end nerve transfer,and end-to-side nerve transfer.Sprague–Dawley rats underwent complete left brachial plexus transection and were divided into four equal groups of eight:no nerve repair,grafted nerve repair,phrenic nerve end-to-end transfer,and end-to-side transfer with a graft sutured to the anterior upper trunk.Resting-state brain functional magnetic resonance imaging was obtained 7 months after surgery.The independent component analysis algorithm was utilized to identify group-level network components of interest and extract resting-state functional connectivity values of each voxel within the component.Alterations in intra-network resting-state functional connectivity were compared among the groups.Target muscle reinnervation was assessed by behavioral observation(elbow flexion)and electromyography.The results showed that alterations in the sensorimotor and interoception networks were mostly related to changes in the peripheral neural pathway.Nerve repair was related to enhanced connectivity within the sensorimotor network,while end-to-side nerve transfer might be more beneficial for restoring control over the affected limb by the original motor representation.The thalamic-cortical pathway was enhanced within the interoception network after nerve repair and end-to-end nerve transfer.Brain areas related to cognition and emotion were enhanced after end-to-side nerve transfer.Our study revealed important brain networks related to different nerve reconstructions.These networks may be potential targets for enhancing motor recovery.展开更多
Based on the introduction of the connotations and characteristics of tourism industrial eco-network,it has expatiated on the connotations of and approaches to enterprise coupling in tourism industrial eco-network.As t...Based on the introduction of the connotations and characteristics of tourism industrial eco-network,it has expatiated on the connotations of and approaches to enterprise coupling in tourism industrial eco-network.As there are different understandings and definitions of these connotations,the following four aspects must be achieved in order to realize coupling in the real sense for the enterprises in the network.① Establish the idea of "the whole is larger than the sum of all the parts",and construct interests community of tourism industrial eco-network.② Construct cooperation mechanism of joint struggle to transfer the advantages of the single to the advantages of the whole.③ Create and maintain strong service culture.④ Avoid as many service blunders as possible and construct damage warning mechanism in industrial eco-network.With the construction of the game model of tourism enterprise coupling and corresponding analysis,the results indicate that the mode of loose cooperation between enterprises in the tourism industry could hardly reach any forceful binding agreements.Consequently it is hard to realize the coordinated effects brought about by the cooperative game of tourism enterprise coupling and these enterprises would often come to a "prisoner dilemma" because of present tiny benefits.In the end,it suggests that during the process of competition tourism enterprises should also strengthen mutual cooperation as relying upon the platform of industrial eco-network.展开更多
In order to improve production and operation ability of medium and small-sized enterprises, an assessment-index system of production and operation ability was proposed, and a corresponding assessment model was establi...In order to improve production and operation ability of medium and small-sized enterprises, an assessment-index system of production and operation ability was proposed, and a corresponding assessment model was established based on BP neural network. The conjunction weights of the neural network were continuously modified from output layer to input layer in the process of neural network training to reduce the errors between the anticipated and actual outputs. The results from an example show that this method is reliable and feasible. The production and operation abilitv of an enterorise with assessed result of 0.833 is fairly oowerful, and that with assessed result of 0.644 is average.展开更多
With the increasingly fierce market competition,manufacturing enterprises have to continuously improve their competitiveness through their collaboration and labor division with each other,i.e.forming manufacturing ent...With the increasingly fierce market competition,manufacturing enterprises have to continuously improve their competitiveness through their collaboration and labor division with each other,i.e.forming manufacturing enterprise collaborative network(MECN)through their collaboration and labor division is an effective guarantee for obtaining competitive advantages.To explore the topology and evolutionary process of MECN,in this paper we investigate an empirical MECN from the viewpoint of complex network theory,and construct an evolutionary model to reproduce the topological properties found in the empirical network.Firstly,large-size empirical data related to the automotive industry are collected to construct an MECN.Topological analysis indicates that the MECN is not a scale-free network,but a small-world network with disassortativity.Small-world property indicates that the enterprises can respond quickly to the market,but disassortativity shows the risk spreading is fast and the coordinated operation is difficult.Then,an evolutionary model based on fitness preferential attachment and entropy-TOPSIS is proposed to capture the features of MECN.Besides,the evolutionary model is compared with a degree-based model in which only node degree is taken into consideration.The simulation results show the proposed evolutionary model can reproduce a number of critical topological properties of empirical MECN,while the degree-based model does not,which validates the effectiveness of the proposed evolutionary model.展开更多
The nature of networked manufacturing and agile manufacturing is to recognize enterprise resources timely and accurately. This paper mainly discusses an enterprise resource model method and the construction process. F...The nature of networked manufacturing and agile manufacturing is to recognize enterprise resources timely and accurately. This paper mainly discusses an enterprise resource model method and the construction process. Furthermore, the system frameworks of software and application are put forward to realize various enterprise resources management based on a resource business process. Thus, we ensure the integration and sharing of enterprise resources for the requirement of networked manufacturing.展开更多
Compared with traditional enterprises, strategy choice and implementation for logistic enterprises has its particularity. This paper discusses character of logistic enterprises and analyzes the different genres of str...Compared with traditional enterprises, strategy choice and implementation for logistic enterprises has its particularity. This paper discusses character of logistic enterprises and analyzes the different genres of strategy, and then the paper introduces the choice of strategy based on network approach. Finally, the authors explain how to ensure the programming and implementation of strategy from different point of view such as financial perspective, client perspective, procedure perspective, internal and organizational learning perspective.展开更多
Perforrmnce indicators play some important roles in enterprise operation. Both researchers and managers have recently pointed out that the identification of correlation between different performmance indicators may le...Perforrmnce indicators play some important roles in enterprise operation. Both researchers and managers have recently pointed out that the identification of correlation between different performmance indicators may lead to a better understanding of business. However, it is becoming more and more difficult to measure and analyze these indicators since the fast growing number of performance indicators and the complex relationships between them The existing categories failed to reflect these changes in an adequate way, and the quantitative analysis methods for identifying the characters of those pefformance indicators are still worthy of investigation. The main objective of this paper is to propose a practical methodology for managing and analyzing performance indicators in enterprises, which focuses on building up a performance indicator system and discovering the characters of those performance indicators by applying complex network methods. The empirical results of a telecommunieation enterprise show that the proposed method can be effective in understanding the correlations between performance indicators.展开更多
For effectively early warning the marketing risk caused along with the varied environment, a BP neural network method was introduced on the basis of analyzing the shortcomings of the risk early warning method, and com...For effectively early warning the marketing risk caused along with the varied environment, a BP neural network method was introduced on the basis of analyzing the shortcomings of the risk early warning method, and combined with the practical conditions of dairy enterprises, the index system caused by the marketing risk was also studied. The'principal component method was used for screening the indexes, the grades and critical values of the marketing risk were determined. Through the configuration of BP network, node processing and error analysis, the early warning resuits of the marketing risk were obtained. The results indicate that BP neural network method can be effectively applied through the function approach in the marketing early warning with incomplete information and complex varied conditions.展开更多
The risk points in the credit guarantee network of steel trade enterprises were identified by using the network analysis method in this paper. Firstly, the formation and operation mechanism of steel trade credit guara...The risk points in the credit guarantee network of steel trade enterprises were identified by using the network analysis method in this paper. Firstly, the formation and operation mechanism of steel trade credit guarantee network was analyzed.Secondly,a guarantee network was established to analyze the related network structure indexes based on the mutual guarantee data of 83 enterprises in a steel trade market. These indexes included centrality,honest broker,and structural hole. The results suggest that network analysis method can be used to find out the risk points of the guarantee network. Additionally,some recommendations are brought forth to reduce or prevent future crises.展开更多
In this paper, we conduct research on the enterprise management and the related employee incentive mechanism under the environment of enterprise social networks. As the sharp change in the environment, the enterprise ...In this paper, we conduct research on the enterprise management and the related employee incentive mechanism under the environment of enterprise social networks. As the sharp change in the environment, the enterprise how to win the competitive advantage for a long time which caused many strategic management thinking, to promote the new development of the theory of the strategic management. Our designed mechanism will enhance the management activities and promote the general value of the employees which has significant meanings.展开更多
Under the background of constructing harmonious economic society, how to realize the coordinated development of regions in the course of region integration is a key problem. According to the relevant theory of enterpr...Under the background of constructing harmonious economic society, how to realize the coordinated development of regions in the course of region integration is a key problem. According to the relevant theory of enterprise gene reconfiguration and enterprise value network construction, we analyzed the problems in the merging course between the value network construction and region economic growth. Finally, we put forward the basic path of coordinated development of regions.展开更多
Optical neural networks have significant advantages in terms of power consumption,parallelism,and high computing speed,which has intrigued extensive attention in both academic and engineering communities.It has been c...Optical neural networks have significant advantages in terms of power consumption,parallelism,and high computing speed,which has intrigued extensive attention in both academic and engineering communities.It has been considered as one of the powerful tools in promoting the fields of imaging processing and object recognition.However,the existing optical system architecture cannot be reconstructed to the realization of multi-functional artificial intelligence systems simultaneously.To push the development of this issue,we propose the pluggable diffractive neural networks(P-DNN),a general paradigm resorting to the cascaded metasurfaces,which can be applied to recognize various tasks by switching internal plug-ins.As the proof-of-principle,the recognition functions of six types of handwritten digits and six types of fashions are numerical simulated and experimental demonstrated at near-infrared regimes.Encouragingly,the proposed paradigm not only improves the flexibility of the optical neural networks but paves the new route for achieving high-speed,low-power and versatile artificial intelligence systems.展开更多
This paper designs an intelligent evaluation approach using a Radial Basis Function (RBF) Artificial Neural Network. We based our approach on establishing a comprehensive advantage evaluating index system that offer...This paper designs an intelligent evaluation approach using a Radial Basis Function (RBF) Artificial Neural Network. We based our approach on establishing a comprehensive advantage evaluating index system that offers scientific substance for creating a development plan and the strategic management of high-tech industry and regional clusters of high-tech enterprises. Furnhermore, this paper selects some typical high-tech enterprises' data to make comprehensive training on the network system. Meanwhile, the paper chooses some enterprises as testing samples to test the method, the result of which proves that this method is truly effective. The research of this paper provides a comprehensive advantage evaluating and managing method for high-tech enterprise.展开更多
Immune changes and inflammatory responses have been identified as central events in the pathological process of spinal co rd injury.They can greatly affect nerve regeneration and functional recovery.However,there is s...Immune changes and inflammatory responses have been identified as central events in the pathological process of spinal co rd injury.They can greatly affect nerve regeneration and functional recovery.However,there is still limited understanding of the peripheral immune inflammato ry response in spinal cord inju ry.In this study.we obtained microRNA expression profiles from the peripheral blood of patients with spinal co rd injury using high-throughput sequencing.We also obtained the mRNA expression profile of spinal cord injury patients from the Gene Expression Omnibus(GEO)database(GSE151371).We identified 54 differentially expressed microRNAs and 1656 diffe rentially expressed genes using bioinformatics approaches.Functional enrichment analysis revealed that various common immune and inflammation-related signaling pathways,such as neutrophil extracellular trap formation pathway,T cell receptor signaling pathway,and nuclear factor-κB signal pathway,we re abnormally activated or inhibited in spinal cord inju ry patient samples.We applied an integrated strategy that combines weighted gene co-expression network analysis,LASSO logistic regression,and SVM-RFE algorithm and identified three biomarke rs associated with spinal cord injury:ANO10,BST1,and ZFP36L2.We verified the expression levels and diagnostic perfo rmance of these three genes in the original training dataset and clinical samples through the receiver operating characteristic curve.Quantitative polymerase chain reaction results showed that ANO20 and BST1 mRNA levels were increased and ZFP36L2 mRNA was decreased in the peripheral blood of spinal cord injury patients.We also constructed a small RNA-mRNA interaction network using Cytoscape.Additionally,we evaluated the proportion of 22 types of immune cells in the peripheral blood of spinal co rd injury patients using the CIBERSORT tool.The proportions of naive B cells,plasma cells,monocytes,and neutrophils were increased while the proportions of memory B cells,CD8^(+)T cells,resting natural killer cells,resting dendritic cells,and eosinophils were markedly decreased in spinal cord injury patients increased compared with healthy subjects,and ANO10,BST1 and ZFP26L2we re closely related to the proportion of certain immune cell types.The findings from this study provide new directions for the development of treatment strategies related to immune inflammation in spinal co rd inju ry and suggest that ANO10,BST2,and ZFP36L2 are potential biomarkers for spinal cord injury.The study was registe red in the Chinese Clinical Trial Registry(registration No.ChiCTR2200066985,December 12,2022).展开更多
Background In early adolescence,youth are highly prone to suicidal behaviours.Identifying modifiable risk factors during this critical phase is a priority to inform effective suicide prevention strategies.Aims To expl...Background In early adolescence,youth are highly prone to suicidal behaviours.Identifying modifiable risk factors during this critical phase is a priority to inform effective suicide prevention strategies.Aims To explore the risk and protective factors of suicidal behaviours(ie,suicidal ideation,plans and attempts)in early adolescence in China using a social-ecological perspective.Methods Using data from the cross-sectional project‘Healthy and Risky Behaviours Among Middle School Students in Anhui Province,China',stratified random cluster sampling was used to select 5724 middle school students who had completed self-report questionnaires in November 2020.Network analysis was employed to examine the correlates of suicidal ideation,plans and attempts at four levels,namely individual(sex,academic performance,serious physical llness/disability,history of self-harm,depression,impulsivity,sleep problems,resilience),family(family economic status,relationship with mother,relationship with father,family violence,childhood abuse,parental mental illness),school(relationship with teachers,relationship with classmates,school-bullying victimisation and perpetration)and social(social support,satisfaction with society).Results In total,37.9%,19.0%and 5.5%of the students reported suicidal ideation,plans and attempts in the past 6 months,respectively.The estimated network revealed that suicidal ideation,plans and attempts were collectively associated with a history of self-harm,sleep problems,childhood abuse,school bullying and victimisation.Centrality analysis indicated that the most influential nodes in the network were history of self-harm and childhood abuse.Notably,the network also showed unique correlates of suicidal ideation(sex,weight=0.60;impulsivity,weight=0.24;family violence,weight=0.17;relationship with teachers,weight=-0.03;school-bullying perpetration,weight=0.22),suicidal plans(social support,weight=-0.15)and suicidal attempts(relationship with mother,weight=-0.10;parental mental llness,weight=0.61).Conclusions This study identified the correlates of suicidal ideation,plans and attempts,and provided practical implications for suicide prevention for young adolescents in China.Firstly,this study highlighted the importance of joint interventions across multiple departments.Secondly,the common risk factors of suicidal ideation,plans and attempts were elucidated.Thirdly,this study proposed target interventions to address the unique influencing factors of suicidal ideation,plans and attempts.展开更多
As an important means for enterprises to promote technological progress,product development and service level,innovation has an absolute role in enhancing enterprises'innovation strength and market strength.In the...As an important means for enterprises to promote technological progress,product development and service level,innovation has an absolute role in enhancing enterprises'innovation strength and market strength.In the context of frequent and rapid product replacement and shortened technological innovation cycle in modern society,through the embedding of social networks,forming platforms for higher education institutions,governments,capital markets,research institutions and intermediary links to promote the integration of innovation and capital development and make the most of every resource has become an important way.From the perspective of social network,the methods and necessary approaches for the establishment of enterprise innovation network are studied in this article.展开更多
基金supported by National Natural Science Foundation of China(Grants No.41971198 and 42371198)Fundamental Research Funds for the Central Universities(Grant No.lzujbky-2023-it24).
文摘In the context of economic globalization,while multinational enterprises from developed countries occupy a high-end position in the global value chain,enterprises from developing countries are often marginalized in the world market.In China,resource-based state-owned enterprises(SOEs)are tasked with the mission of safeguarding resource security,and their internationalization development ideas and strategic deployment are significantly and fundamentally different from those of other non-state-owned enterprises and large multinational corporations.This study provides ideas for the globalization policies of enterprises in developing countries.We consider J Group in western China as a case and discuss its productive investment and global production network development from 2010 to 2019.We found that J Group was‘Partly'globalized,and there are multiple core nodes with the characteristics of centralized and decentralized coexistence in the production network;in addition,the overall layout centre shifted to Southeast Asia and China;however,its global production was restricted by the enterprise's investment security considerations,support and restrictions of the home country,political security risk of the host country,and sanctions from the West.These findings provide insights for future research:under the wave of anti-globalization and'internal circulation as the main body',resource SOEs should consider the potential risk of investment,especially keeping the middle and downstream industrial chain in China as much as possible.
文摘Medical procedures are inherently invasive and carry the risk of inducing pain to the mind and body.Recently,efforts have been made to alleviate the discomfort associated with invasive medical procedures through the use of virtual reality(VR)technology.VR has been demonstrated to be an effective treatment for pain associated with medical procedures,as well as for chronic pain conditions for which no effective treatment has been established.The precise mechanism by which the diversion from reality facilitated by VR contributes to the diminution of pain and anxiety has yet to be elucidated.However,the provision of positive images through VR-based visual stimulation may enhance the functionality of brain networks.The salience network is diminished,while the default mode network is enhanced.Additionally,the medial prefrontal cortex may establish a stronger connection with the default mode network,which could result in a reduction of pain and anxiety.Further research into the potential of VR technology to alleviate pain could lead to a reduction in the number of individuals who overdose on painkillers and contribute to positive change in the medical field.
基金Supported by National Key Technology Research and Developmental Program of China,No.2022YFC2704400 and No.2022YFC2704405.
文摘BACKGROUND Mitochondrial genes are involved in tumor metabolism in ovarian cancer(OC)and affect immune cell infiltration and treatment responses.AIM To predict prognosis and immunotherapy response in patients diagnosed with OC using mitochondrial genes and neural networks.METHODS Prognosis,immunotherapy efficacy,and next-generation sequencing data of patients with OC were downloaded from The Cancer Genome Atlas and Gene Expression Omnibus.Mitochondrial genes were sourced from the MitoCarta3.0 database.The discovery cohort for model construction was created from 70% of the patients,whereas the remaining 30% constituted the validation cohort.Using the expression of mitochondrial genes as the predictor variable and based on neural network algorithm,the overall survival time and immunotherapy efficacy(complete or partial response)of patients were predicted.RESULTS In total,375 patients with OC were included to construct the prognostic model,and 26 patients were included to construct the immune efficacy model.The average area under the receiver operating characteristic curve of the prognostic model was 0.7268[95% confidence interval(CI):0.7258-0.7278]in the discovery cohort and 0.6475(95%CI:0.6466-0.6484)in the validation cohort.The average area under the receiver operating characteristic curve of the immunotherapy efficacy model was 0.9444(95%CI:0.8333-1.0000)in the discovery cohort and 0.9167(95%CI:0.6667-1.0000)in the validation cohort.CONCLUSION The application of mitochondrial genes and neural networks has the potential to predict prognosis and immunotherapy response in patients with OC,providing valuable insights into personalized treatment strategies.
基金supported by the National Natural Science Foundation of China,Nos.81871836(to MZ),82172554(to XH),and 81802249(to XH),81902301(to JW)the National Key R&D Program of China,Nos.2018YFC2001600(to JX)and 2018YFC2001604(to JX)+3 种基金Shanghai Rising Star Program,No.19QA1409000(to MZ)Shanghai Municipal Commission of Health and Family Planning,No.2018YQ02(to MZ)Shanghai Youth Top Talent Development PlanShanghai“Rising Stars of Medical Talent”Youth Development Program,No.RY411.19.01.10(to XH)。
文摘Distinct brain remodeling has been found after different nerve reconstruction strategies,including motor representation of the affected limb.However,differences among reconstruction strategies at the brain network level have not been elucidated.This study aimed to explore intranetwork changes related to altered peripheral neural pathways after different nerve reconstruction surgeries,including nerve repair,endto-end nerve transfer,and end-to-side nerve transfer.Sprague–Dawley rats underwent complete left brachial plexus transection and were divided into four equal groups of eight:no nerve repair,grafted nerve repair,phrenic nerve end-to-end transfer,and end-to-side transfer with a graft sutured to the anterior upper trunk.Resting-state brain functional magnetic resonance imaging was obtained 7 months after surgery.The independent component analysis algorithm was utilized to identify group-level network components of interest and extract resting-state functional connectivity values of each voxel within the component.Alterations in intra-network resting-state functional connectivity were compared among the groups.Target muscle reinnervation was assessed by behavioral observation(elbow flexion)and electromyography.The results showed that alterations in the sensorimotor and interoception networks were mostly related to changes in the peripheral neural pathway.Nerve repair was related to enhanced connectivity within the sensorimotor network,while end-to-side nerve transfer might be more beneficial for restoring control over the affected limb by the original motor representation.The thalamic-cortical pathway was enhanced within the interoception network after nerve repair and end-to-end nerve transfer.Brain areas related to cognition and emotion were enhanced after end-to-side nerve transfer.Our study revealed important brain networks related to different nerve reconstructions.These networks may be potential targets for enhancing motor recovery.
基金Supported by Sichuan Circular Economy Research Centre of Sichuan Province Key Research Base of Philosophy and Social Science in2008(XHJJ-0808)~~
文摘Based on the introduction of the connotations and characteristics of tourism industrial eco-network,it has expatiated on the connotations of and approaches to enterprise coupling in tourism industrial eco-network.As there are different understandings and definitions of these connotations,the following four aspects must be achieved in order to realize coupling in the real sense for the enterprises in the network.① Establish the idea of "the whole is larger than the sum of all the parts",and construct interests community of tourism industrial eco-network.② Construct cooperation mechanism of joint struggle to transfer the advantages of the single to the advantages of the whole.③ Create and maintain strong service culture.④ Avoid as many service blunders as possible and construct damage warning mechanism in industrial eco-network.With the construction of the game model of tourism enterprise coupling and corresponding analysis,the results indicate that the mode of loose cooperation between enterprises in the tourism industry could hardly reach any forceful binding agreements.Consequently it is hard to realize the coordinated effects brought about by the cooperative game of tourism enterprise coupling and these enterprises would often come to a "prisoner dilemma" because of present tiny benefits.In the end,it suggests that during the process of competition tourism enterprises should also strengthen mutual cooperation as relying upon the platform of industrial eco-network.
基金Project 2001FJJ036 supported by Society Science Foundation of Henan Province
文摘In order to improve production and operation ability of medium and small-sized enterprises, an assessment-index system of production and operation ability was proposed, and a corresponding assessment model was established based on BP neural network. The conjunction weights of the neural network were continuously modified from output layer to input layer in the process of neural network training to reduce the errors between the anticipated and actual outputs. The results from an example show that this method is reliable and feasible. The production and operation abilitv of an enterorise with assessed result of 0.833 is fairly oowerful, and that with assessed result of 0.644 is average.
基金the National Natural Science Foundation of China(Grant Nos.51475347 and 51875429).
文摘With the increasingly fierce market competition,manufacturing enterprises have to continuously improve their competitiveness through their collaboration and labor division with each other,i.e.forming manufacturing enterprise collaborative network(MECN)through their collaboration and labor division is an effective guarantee for obtaining competitive advantages.To explore the topology and evolutionary process of MECN,in this paper we investigate an empirical MECN from the viewpoint of complex network theory,and construct an evolutionary model to reproduce the topological properties found in the empirical network.Firstly,large-size empirical data related to the automotive industry are collected to construct an MECN.Topological analysis indicates that the MECN is not a scale-free network,but a small-world network with disassortativity.Small-world property indicates that the enterprises can respond quickly to the market,but disassortativity shows the risk spreading is fast and the coordinated operation is difficult.Then,an evolutionary model based on fitness preferential attachment and entropy-TOPSIS is proposed to capture the features of MECN.Besides,the evolutionary model is compared with a degree-based model in which only node degree is taken into consideration.The simulation results show the proposed evolutionary model can reproduce a number of critical topological properties of empirical MECN,while the degree-based model does not,which validates the effectiveness of the proposed evolutionary model.
文摘The nature of networked manufacturing and agile manufacturing is to recognize enterprise resources timely and accurately. This paper mainly discusses an enterprise resource model method and the construction process. Furthermore, the system frameworks of software and application are put forward to realize various enterprise resources management based on a resource business process. Thus, we ensure the integration and sharing of enterprise resources for the requirement of networked manufacturing.
文摘Compared with traditional enterprises, strategy choice and implementation for logistic enterprises has its particularity. This paper discusses character of logistic enterprises and analyzes the different genres of strategy, and then the paper introduces the choice of strategy based on network approach. Finally, the authors explain how to ensure the programming and implementation of strategy from different point of view such as financial perspective, client perspective, procedure perspective, internal and organizational learning perspective.
基金This work was partially supported by the Project of National Natural Science Foundation for Distinguished Young Scholars under Grants No.70901009,No.71202155,the Youth Research and Innovation Program in Beijing University of Posts and Telecommunications,the National Basic Research Program of China under Grant No.2012CB315805
文摘Perforrmnce indicators play some important roles in enterprise operation. Both researchers and managers have recently pointed out that the identification of correlation between different performmance indicators may lead to a better understanding of business. However, it is becoming more and more difficult to measure and analyze these indicators since the fast growing number of performance indicators and the complex relationships between them The existing categories failed to reflect these changes in an adequate way, and the quantitative analysis methods for identifying the characters of those pefformance indicators are still worthy of investigation. The main objective of this paper is to propose a practical methodology for managing and analyzing performance indicators in enterprises, which focuses on building up a performance indicator system and discovering the characters of those performance indicators by applying complex network methods. The empirical results of a telecommunieation enterprise show that the proposed method can be effective in understanding the correlations between performance indicators.
文摘For effectively early warning the marketing risk caused along with the varied environment, a BP neural network method was introduced on the basis of analyzing the shortcomings of the risk early warning method, and combined with the practical conditions of dairy enterprises, the index system caused by the marketing risk was also studied. The'principal component method was used for screening the indexes, the grades and critical values of the marketing risk were determined. Through the configuration of BP network, node processing and error analysis, the early warning resuits of the marketing risk were obtained. The results indicate that BP neural network method can be effectively applied through the function approach in the marketing early warning with incomplete information and complex varied conditions.
基金Social Science Programs Foundation of Ministry of Education of China(No.10YJA910002)
文摘The risk points in the credit guarantee network of steel trade enterprises were identified by using the network analysis method in this paper. Firstly, the formation and operation mechanism of steel trade credit guarantee network was analyzed.Secondly,a guarantee network was established to analyze the related network structure indexes based on the mutual guarantee data of 83 enterprises in a steel trade market. These indexes included centrality,honest broker,and structural hole. The results suggest that network analysis method can be used to find out the risk points of the guarantee network. Additionally,some recommendations are brought forth to reduce or prevent future crises.
文摘In this paper, we conduct research on the enterprise management and the related employee incentive mechanism under the environment of enterprise social networks. As the sharp change in the environment, the enterprise how to win the competitive advantage for a long time which caused many strategic management thinking, to promote the new development of the theory of the strategic management. Our designed mechanism will enhance the management activities and promote the general value of the employees which has significant meanings.
文摘Under the background of constructing harmonious economic society, how to realize the coordinated development of regions in the course of region integration is a key problem. According to the relevant theory of enterprise gene reconfiguration and enterprise value network construction, we analyzed the problems in the merging course between the value network construction and region economic growth. Finally, we put forward the basic path of coordinated development of regions.
基金The authors acknowledge the funding provided by the National Key R&D Program of China(2021YFA1401200)Beijing Outstanding Young Scientist Program(BJJWZYJH01201910007022)+2 种基金National Natural Science Foundation of China(No.U21A20140,No.92050117,No.62005017)programBeijing Municipal Science&Technology Commission,Administrative Commission of Zhongguancun Science Park(No.Z211100004821009)This work was supported by the Synergetic Extreme Condition User Facility(SECUF).
文摘Optical neural networks have significant advantages in terms of power consumption,parallelism,and high computing speed,which has intrigued extensive attention in both academic and engineering communities.It has been considered as one of the powerful tools in promoting the fields of imaging processing and object recognition.However,the existing optical system architecture cannot be reconstructed to the realization of multi-functional artificial intelligence systems simultaneously.To push the development of this issue,we propose the pluggable diffractive neural networks(P-DNN),a general paradigm resorting to the cascaded metasurfaces,which can be applied to recognize various tasks by switching internal plug-ins.As the proof-of-principle,the recognition functions of six types of handwritten digits and six types of fashions are numerical simulated and experimental demonstrated at near-infrared regimes.Encouragingly,the proposed paradigm not only improves the flexibility of the optical neural networks but paves the new route for achieving high-speed,low-power and versatile artificial intelligence systems.
文摘This paper designs an intelligent evaluation approach using a Radial Basis Function (RBF) Artificial Neural Network. We based our approach on establishing a comprehensive advantage evaluating index system that offers scientific substance for creating a development plan and the strategic management of high-tech industry and regional clusters of high-tech enterprises. Furnhermore, this paper selects some typical high-tech enterprises' data to make comprehensive training on the network system. Meanwhile, the paper chooses some enterprises as testing samples to test the method, the result of which proves that this method is truly effective. The research of this paper provides a comprehensive advantage evaluating and managing method for high-tech enterprise.
基金supported by the Notional Natural Science Foundation of China,No.81960417 (to JX)Guangxi Key Research and Development Program,No.GuiKeA B20159027 (to JX)the Natural Science Foundation of Guangxi Zhuang Autonomous Region,No.2022GXNSFBA035545 (to YG)。
文摘Immune changes and inflammatory responses have been identified as central events in the pathological process of spinal co rd injury.They can greatly affect nerve regeneration and functional recovery.However,there is still limited understanding of the peripheral immune inflammato ry response in spinal cord inju ry.In this study.we obtained microRNA expression profiles from the peripheral blood of patients with spinal co rd injury using high-throughput sequencing.We also obtained the mRNA expression profile of spinal cord injury patients from the Gene Expression Omnibus(GEO)database(GSE151371).We identified 54 differentially expressed microRNAs and 1656 diffe rentially expressed genes using bioinformatics approaches.Functional enrichment analysis revealed that various common immune and inflammation-related signaling pathways,such as neutrophil extracellular trap formation pathway,T cell receptor signaling pathway,and nuclear factor-κB signal pathway,we re abnormally activated or inhibited in spinal cord inju ry patient samples.We applied an integrated strategy that combines weighted gene co-expression network analysis,LASSO logistic regression,and SVM-RFE algorithm and identified three biomarke rs associated with spinal cord injury:ANO10,BST1,and ZFP36L2.We verified the expression levels and diagnostic perfo rmance of these three genes in the original training dataset and clinical samples through the receiver operating characteristic curve.Quantitative polymerase chain reaction results showed that ANO20 and BST1 mRNA levels were increased and ZFP36L2 mRNA was decreased in the peripheral blood of spinal cord injury patients.We also constructed a small RNA-mRNA interaction network using Cytoscape.Additionally,we evaluated the proportion of 22 types of immune cells in the peripheral blood of spinal co rd injury patients using the CIBERSORT tool.The proportions of naive B cells,plasma cells,monocytes,and neutrophils were increased while the proportions of memory B cells,CD8^(+)T cells,resting natural killer cells,resting dendritic cells,and eosinophils were markedly decreased in spinal cord injury patients increased compared with healthy subjects,and ANO10,BST1 and ZFP26L2we re closely related to the proportion of certain immune cell types.The findings from this study provide new directions for the development of treatment strategies related to immune inflammation in spinal co rd inju ry and suggest that ANO10,BST2,and ZFP36L2 are potential biomarkers for spinal cord injury.The study was registe red in the Chinese Clinical Trial Registry(registration No.ChiCTR2200066985,December 12,2022).
文摘Background In early adolescence,youth are highly prone to suicidal behaviours.Identifying modifiable risk factors during this critical phase is a priority to inform effective suicide prevention strategies.Aims To explore the risk and protective factors of suicidal behaviours(ie,suicidal ideation,plans and attempts)in early adolescence in China using a social-ecological perspective.Methods Using data from the cross-sectional project‘Healthy and Risky Behaviours Among Middle School Students in Anhui Province,China',stratified random cluster sampling was used to select 5724 middle school students who had completed self-report questionnaires in November 2020.Network analysis was employed to examine the correlates of suicidal ideation,plans and attempts at four levels,namely individual(sex,academic performance,serious physical llness/disability,history of self-harm,depression,impulsivity,sleep problems,resilience),family(family economic status,relationship with mother,relationship with father,family violence,childhood abuse,parental mental illness),school(relationship with teachers,relationship with classmates,school-bullying victimisation and perpetration)and social(social support,satisfaction with society).Results In total,37.9%,19.0%and 5.5%of the students reported suicidal ideation,plans and attempts in the past 6 months,respectively.The estimated network revealed that suicidal ideation,plans and attempts were collectively associated with a history of self-harm,sleep problems,childhood abuse,school bullying and victimisation.Centrality analysis indicated that the most influential nodes in the network were history of self-harm and childhood abuse.Notably,the network also showed unique correlates of suicidal ideation(sex,weight=0.60;impulsivity,weight=0.24;family violence,weight=0.17;relationship with teachers,weight=-0.03;school-bullying perpetration,weight=0.22),suicidal plans(social support,weight=-0.15)and suicidal attempts(relationship with mother,weight=-0.10;parental mental llness,weight=0.61).Conclusions This study identified the correlates of suicidal ideation,plans and attempts,and provided practical implications for suicide prevention for young adolescents in China.Firstly,this study highlighted the importance of joint interventions across multiple departments.Secondly,the common risk factors of suicidal ideation,plans and attempts were elucidated.Thirdly,this study proposed target interventions to address the unique influencing factors of suicidal ideation,plans and attempts.
基金Natural Science Foundation of Heilongjiang Province(LH2019G019)Philosophy and Social Science General Project of Heilongjiang Province(18JYB153)Scientific Research Foundation for Cultivated and Introduced Talents of Heilongjiang Bayi Agricultural University。
文摘As an important means for enterprises to promote technological progress,product development and service level,innovation has an absolute role in enhancing enterprises'innovation strength and market strength.In the context of frequent and rapid product replacement and shortened technological innovation cycle in modern society,through the embedding of social networks,forming platforms for higher education institutions,governments,capital markets,research institutions and intermediary links to promote the integration of innovation and capital development and make the most of every resource has become an important way.From the perspective of social network,the methods and necessary approaches for the establishment of enterprise innovation network are studied in this article.