Background:College students face significant academic and physiological changes,making them more susceptible to psychological issues such as depression,self-injury,and suicidal ideation.Feelings of defeat can exacerba...Background:College students face significant academic and physiological changes,making them more susceptible to psychological issues such as depression,self-injury,and suicidal ideation.Feelings of defeat can exacerbate these risks by increasing academic stress.However,interpersonal relationships can moderate the impact of academic stress on students’mental health.Utilizing the presage–process–product model,this study aims to empirically investigate how feelings of defeat influence depression,self-injury,and suicidal ideation among college students.Additionally,it explores the mediating role of academic stress and the moderating role of various types of interpersonal relationships.Methods:A total of 1612 college students(750 females,862 males,mean age=19.64±0.62 years)were recruited through cluster sampling.Data were collected via offline questionnaires administered by a trained psychology teacher and a postgraduate student,ensuring high reliability with two examiners per class.Latent profile analysis(LPA)was used to examine the impact of defeat on mental health outcomes,while mediation analysis was conducted to assess the roles of academic stress and interpersonal relationships.Results:1.Defeat is identified as a significant risk factor for mental health issues among college students;2.Four distinct patterns of interpersonal relationships were identified:the interpersonal-relationship risk group,the father–child-relationship high-risk group,the general interpersonal-relationship group,and the superior interpersonal-relationship group;3.Academic stress partially mediates the relationship between defeat and mental health issues such as depression,self-injury,and suicidal ideation;4.Different interpersonal relationship models moderate the impact of academic stress on depression and suicidal ideation.Conclusion:Defeat is a significant risk factor for mental health problems in college students.Academic stress partially mediates the negative impact of defeat on mental health,while patterns of interpersonal relationships moderate this impact.Effective early prevention and intervention should focus on monitoring students’stress levels and fostering warm,positive parent–child relationships.展开更多
BACKGROUND Pediatric abdominal infection is a common but serious disease that requires timely and effective treatment.In surgical treatment,accurate diagnosis and rational application of antibiotics are the keys to im...BACKGROUND Pediatric abdominal infection is a common but serious disease that requires timely and effective treatment.In surgical treatment,accurate diagnosis and rational application of antibiotics are the keys to improving treatment effects.AIM To investigate the effect of broad-spectrum bacterial detection on postoperative antibiotic therapy.METHODS A total of 100 children with abdominal infection who received surgical treatment in our hospital from September 2020 to July 2021 were grouped.The observation group collected blood samples upon admission and sent them for broad-spectrum bacterial infection nucleic acid testing,and collected pus or exudate during the operation for bacterial culture and drug sensitivity testing;the control group only sent bacterial culture and drug sensitivity testing during the operation.RESULTS White blood cell count,C-reactive protein,procalcitonin,3 days after surgery,showed better postoperative index than the control group(P<0.05).The hospital stay in the observation group was significantly shorter than that in the control group.The hospitalization cost in the observation group was significantly lower than that in the control group,and the difference between the two groups was statistically significant(P<0.05).CONCLUSION Early detection of broad-spectrum bacterial infection nucleic acids in pediatric abdominal infections can help identify pathogens sooner and guide the appropriate use of antibiotics,improving treatment outcomes and reducing medical costs to some extent.展开更多
BACKGROUND： It has been demonstrated that patients with functional dyspepsia have experiences social life stress events, and accompanied by psychological disorders, mainly manifested as depression and anxiety.Mental ...BACKGROUND： It has been demonstrated that patients with functional dyspepsia have experiences social life stress events, and accompanied by psychological disorders, mainly manifested as depression and anxiety.Mental factors can lead to excessive gastrointestinal consensual reaction, and result in different brain-gut axis disturbance, and then cause the gastrointestinal sensorimotor abnormality and endocrine changes.OBJECTIVE： To observe the effect of antidepressant treatment on the changes of water load and serum cortisol in patients with functional dyspepsia, and analyze the therapeutic mechanism.DESIGN： A comparative observation.SETTING： The First Affiliated Hospital o Zhengzhou University.PARTICIPANTS： Forty-five patients with functional dyspepsia accompanied by depression were selected from the Department of Gastroenterology, the First Affiliated Hospital of Zhengzhou University from July 2004 to July 2006, and they were 25 - 65 years of age, and their disease courses ranged 1 - 10 years. They were all accorded with the diagnostic standards for Rome Ⅱ functional dyspepsia functional dyspepsia. As the patients＇ will, they were divided into treatment group （n =30, 12 males and 18 females） and control group （n =15, 6 males and 9 females）, and there were no significant differences in the data between the two groups （P 〉 0.05）. The programs were discussed and agreed by the committee of medical ethics of the First Affiliated Hospital of Zhengzhou University. Informed contents were obtained from all the patients.METHODS： In the treatment group, the patients were treated with venlafaxine sustained release capsule （75 mg per day）, and those with sleep disorder were added by benzodiazepines （alprazolam）. In the control group, the patients were given routine treatments of antacid, prokinetics, etc. Before and after 8-week treatment, the following examinations were performed： ① The gastrointestinal symptoms were assessed according to the symptoms; ② The severity of depression was evaluated with Hamilton depression scale （HAMD）; ③The relaxation of proximal stomach was observed using water load test; ④ The serum level of cortisol was detected.MAIN OUTCOME MEASURES： ① Symptom score; ② HAMD score; ③ Water load amount; ④Serum level of cortisol.RESULTS： All the 45 patients were involved in the analysis of results. ① Symptom score： The scores of gastrointestinal symptoms were decreased as compared with those before treatment in both the treatment group and control group （P 〈 0.05）. ② HAMD scores： The scores of HAMD were decreased as compared with those before treatment in both the treatment group and control group （P 〈 0.05）. ③ Water load amount：The total effective rate was significantly higher in the treatment group than the control group （P 〈 0.05）. ④The serum levels of cortisol after treatment were significantly lower than those before treatment in the patients with severe gastrointestinal symptoms in the treatment group and control group （P 〈 0.05）.CONCLUSION： Antidepressants can normalize the cortisol level of patients with functional dyspepsia, and then decrease gastric sensitivity and ameliorates the receptive relaxation of proximal stomach, also increase the water load amount correspondingly, and finally control the gastrointestinal symptoms of functional dyspepsia.展开更多
INTRODUCTION Despite the technological advances in neu-roimaging, there is still no way of directly observingthe fully integrated functioning of the human brain.
目的：了解我市主城区小学生心理健康状况,为进一步干预提供科学依据。方法：采用分层随机抽样的方法对重庆市主城区3 647名4~6年级小学生,用心理健康诊断测验（Mental health test,MHT）进行横断面调查研究。结果：小学生心理健康问题...目的：了解我市主城区小学生心理健康状况,为进一步干预提供科学依据。方法：采用分层随机抽样的方法对重庆市主城区3 647名4~6年级小学生,用心理健康诊断测验（Mental health test,MHT）进行横断面调查研究。结果：小学生心理健康问题总分检出率为3%,女生的学习焦虑、身体症状因子分显著高于男生,而男生的孤独倾向分更高。4年级的孤独倾向、身体症状因子分显著高于其它年级;5年级的学习焦虑、过敏倾向、冲动倾向因子分显著高于其他年级;6年级的自责倾向、恐怖倾向因子分显著高于其他年级。农民工小学的孤独倾向、恐怖倾向因子分及普通小学的身体症状因子分显著高于重点小学学生。结论：重庆市主城区高年级小学生心理健康状况不容乐观,需采取有针对性的干预措施。展开更多
基金funded by the Humanities and Social Sciences Foundation of the Ministry of Education(23JDSZ3163)the 2023 Project of the“14th Five-Year Plan”for Education Science of Shandong Province and the Achievements of the Famous Tutors’Workshop in Shandong Province(202405).
文摘Background:College students face significant academic and physiological changes,making them more susceptible to psychological issues such as depression,self-injury,and suicidal ideation.Feelings of defeat can exacerbate these risks by increasing academic stress.However,interpersonal relationships can moderate the impact of academic stress on students’mental health.Utilizing the presage–process–product model,this study aims to empirically investigate how feelings of defeat influence depression,self-injury,and suicidal ideation among college students.Additionally,it explores the mediating role of academic stress and the moderating role of various types of interpersonal relationships.Methods:A total of 1612 college students(750 females,862 males,mean age=19.64±0.62 years)were recruited through cluster sampling.Data were collected via offline questionnaires administered by a trained psychology teacher and a postgraduate student,ensuring high reliability with two examiners per class.Latent profile analysis(LPA)was used to examine the impact of defeat on mental health outcomes,while mediation analysis was conducted to assess the roles of academic stress and interpersonal relationships.Results:1.Defeat is identified as a significant risk factor for mental health issues among college students;2.Four distinct patterns of interpersonal relationships were identified:the interpersonal-relationship risk group,the father–child-relationship high-risk group,the general interpersonal-relationship group,and the superior interpersonal-relationship group;3.Academic stress partially mediates the relationship between defeat and mental health issues such as depression,self-injury,and suicidal ideation;4.Different interpersonal relationship models moderate the impact of academic stress on depression and suicidal ideation.Conclusion:Defeat is a significant risk factor for mental health problems in college students.Academic stress partially mediates the negative impact of defeat on mental health,while patterns of interpersonal relationships moderate this impact.Effective early prevention and intervention should focus on monitoring students’stress levels and fostering warm,positive parent–child relationships.
基金Zhangjiakou Science and Technology Tackling Program,No.2021099D.
文摘BACKGROUND Pediatric abdominal infection is a common but serious disease that requires timely and effective treatment.In surgical treatment,accurate diagnosis and rational application of antibiotics are the keys to improving treatment effects.AIM To investigate the effect of broad-spectrum bacterial detection on postoperative antibiotic therapy.METHODS A total of 100 children with abdominal infection who received surgical treatment in our hospital from September 2020 to July 2021 were grouped.The observation group collected blood samples upon admission and sent them for broad-spectrum bacterial infection nucleic acid testing,and collected pus or exudate during the operation for bacterial culture and drug sensitivity testing;the control group only sent bacterial culture and drug sensitivity testing during the operation.RESULTS White blood cell count,C-reactive protein,procalcitonin,3 days after surgery,showed better postoperative index than the control group(P<0.05).The hospital stay in the observation group was significantly shorter than that in the control group.The hospitalization cost in the observation group was significantly lower than that in the control group,and the difference between the two groups was statistically significant(P<0.05).CONCLUSION Early detection of broad-spectrum bacterial infection nucleic acids in pediatric abdominal infections can help identify pathogens sooner and guide the appropriate use of antibiotics,improving treatment outcomes and reducing medical costs to some extent.
文摘BACKGROUND： It has been demonstrated that patients with functional dyspepsia have experiences social life stress events, and accompanied by psychological disorders, mainly manifested as depression and anxiety.Mental factors can lead to excessive gastrointestinal consensual reaction, and result in different brain-gut axis disturbance, and then cause the gastrointestinal sensorimotor abnormality and endocrine changes.OBJECTIVE： To observe the effect of antidepressant treatment on the changes of water load and serum cortisol in patients with functional dyspepsia, and analyze the therapeutic mechanism.DESIGN： A comparative observation.SETTING： The First Affiliated Hospital o Zhengzhou University.PARTICIPANTS： Forty-five patients with functional dyspepsia accompanied by depression were selected from the Department of Gastroenterology, the First Affiliated Hospital of Zhengzhou University from July 2004 to July 2006, and they were 25 - 65 years of age, and their disease courses ranged 1 - 10 years. They were all accorded with the diagnostic standards for Rome Ⅱ functional dyspepsia functional dyspepsia. As the patients＇ will, they were divided into treatment group （n =30, 12 males and 18 females） and control group （n =15, 6 males and 9 females）, and there were no significant differences in the data between the two groups （P 〉 0.05）. The programs were discussed and agreed by the committee of medical ethics of the First Affiliated Hospital of Zhengzhou University. Informed contents were obtained from all the patients.METHODS： In the treatment group, the patients were treated with venlafaxine sustained release capsule （75 mg per day）, and those with sleep disorder were added by benzodiazepines （alprazolam）. In the control group, the patients were given routine treatments of antacid, prokinetics, etc. Before and after 8-week treatment, the following examinations were performed： ① The gastrointestinal symptoms were assessed according to the symptoms; ② The severity of depression was evaluated with Hamilton depression scale （HAMD）; ③The relaxation of proximal stomach was observed using water load test; ④ The serum level of cortisol was detected.MAIN OUTCOME MEASURES： ① Symptom score; ② HAMD score; ③ Water load amount; ④Serum level of cortisol.RESULTS： All the 45 patients were involved in the analysis of results. ① Symptom score： The scores of gastrointestinal symptoms were decreased as compared with those before treatment in both the treatment group and control group （P 〈 0.05）. ② HAMD scores： The scores of HAMD were decreased as compared with those before treatment in both the treatment group and control group （P 〈 0.05）. ③ Water load amount：The total effective rate was significantly higher in the treatment group than the control group （P 〈 0.05）. ④The serum levels of cortisol after treatment were significantly lower than those before treatment in the patients with severe gastrointestinal symptoms in the treatment group and control group （P 〈 0.05）.CONCLUSION： Antidepressants can normalize the cortisol level of patients with functional dyspepsia, and then decrease gastric sensitivity and ameliorates the receptive relaxation of proximal stomach, also increase the water load amount correspondingly, and finally control the gastrointestinal symptoms of functional dyspepsia.
文摘INTRODUCTION Despite the technological advances in neu-roimaging, there is still no way of directly observingthe fully integrated functioning of the human brain.
文摘目的：了解我市主城区小学生心理健康状况,为进一步干预提供科学依据。方法：采用分层随机抽样的方法对重庆市主城区3 647名4~6年级小学生,用心理健康诊断测验（Mental health test,MHT）进行横断面调查研究。结果：小学生心理健康问题总分检出率为3%,女生的学习焦虑、身体症状因子分显著高于男生,而男生的孤独倾向分更高。4年级的孤独倾向、身体症状因子分显著高于其它年级;5年级的学习焦虑、过敏倾向、冲动倾向因子分显著高于其他年级;6年级的自责倾向、恐怖倾向因子分显著高于其他年级。农民工小学的孤独倾向、恐怖倾向因子分及普通小学的身体症状因子分显著高于重点小学学生。结论：重庆市主城区高年级小学生心理健康状况不容乐观,需采取有针对性的干预措施。
