This study was aimed to explore the associations between the combined effects of several polymorphisms in the PPAR-γ and RXR-α gene and environmental factors with the risk of metabolic syndrome by back-error propaga...This study was aimed to explore the associations between the combined effects of several polymorphisms in the PPAR-γ and RXR-α gene and environmental factors with the risk of metabolic syndrome by back-error propaga- tion artificial neural network (BPANN). We established the model based on data gathered from metabolic syndrome patients (n = 1012) and normal controls (n = 1069) by BPANN. Mean impact value (MIV) for each input variable was calculated and the sequence of factors was sorted according to their absolute MIVs. Generalized multifactor dimensionality reduction (GMDR) confirmed a joint effect of PPAR-9" and RXR-a based on the results from BPANN. By BPANN analysis, the sequences according to the importance of metabolic syndrome risk fac- tors were in the order of body mass index (BMI), serum adiponectin, rs4240711, gender, rs4842194, family history of type 2 diabetes, rs2920502, physical activity, alcohol drinking, rs3856806, family history of hypertension, rs1045570, rs6537944, age, rs17817276, family history of hyperlipidemia, smoking, rs1801282 and rs3132291. However, no polymorphism was statistically significant in multiple logistic regression analysis. After controlling for environmental factors, A1, A2, B1 and B2 (rs4240711, rs4842194, rs2920502 and rs3856806) models were the best models (cross-validation consistency 10/10, P = 0.0107) with the GMDR method. In conclusion, the interaction of the PPAR-γ and RXR-α gene could play a role in susceptibility to metabolic syndrome. A more realistic model is obtained by using BPANN to screen out determinants of diseases of multiple etiologies like metabolic syndrome.展开更多
Various force disturbances influence the thrust force of linear motors when a linear motor (LM) is running. Among all of force disturbances, the force ripple is the dominant while a linear motor runs in low speed. I...Various force disturbances influence the thrust force of linear motors when a linear motor (LM) is running. Among all of force disturbances, the force ripple is the dominant while a linear motor runs in low speed. In order to suppress the force ripple, back propagation(BP) neural network is proposed to learn the function of the force ripple of linear motors, and the acquisition method of training samples is proposed based on a disturbance observer. An off-line BP neural network is used mainly because of its high running efficiency and the real-time requirement of the servo control system of a linear motor. By using the function, the force ripple is on-line compensated according to the position of the LM. The experimental results show that the force ripple is effectively suppressed by the compensation of the BP neural network.展开更多
Aiming at the problem that back propagation(BP)neural network predicts the low accuracy rate of fluff fabric after fluffing process,a BP neural network model optimized by particle swarm optimization(PSO)algorithm is p...Aiming at the problem that back propagation(BP)neural network predicts the low accuracy rate of fluff fabric after fluffing process,a BP neural network model optimized by particle swarm optimization(PSO)algorithm is proposed.The sliced image is obtained by the principle of light-cutting imaging.The fluffy region of the adaptive image segmentation is extracted by the Freeman chain code principle.The upper edge coordinate information of the fabric is subjected to one-dimensional discrete wavelet decomposition to obtain high frequency information and low frequency information.After comparison and analysis,the BP neural network was trained by high frequency information,and the PSO algorithm was used to optimize the BP neural network.The optimized BP neural network has better weights and thresholds.The experimental results show that the accuracy of the optimized BP neural network after applying high-frequency information training is 97.96%,which is 3.79%higher than that of the unoptimized BP neural network,and has higher detection accuracy.展开更多
Electronic components' reliability has become the key of the complex system mission execution. Analog circuit is an important part of electronic components. Its fault diagnosis is far more challenging than that of...Electronic components' reliability has become the key of the complex system mission execution. Analog circuit is an important part of electronic components. Its fault diagnosis is far more challenging than that of digital circuit. Simulations and applications have shown that the methods based on BP neural network are effective in analog circuit fault diagnosis. Aiming at the tolerance of analog circuit,a combinatorial optimization diagnosis scheme was proposed with back propagation( BP) neural network( BPNN).The main contributions of this scheme included two parts:( 1) the random tolerance samples were added into the nominal training samples to establish new training samples,which were used to train the BP neural network based diagnosis model;( 2) the initial weights of the BP neural network were optimized by genetic algorithm( GA) to avoid local minima,and the BP neural network was tuned with Levenberg-Marquardt algorithm( LMA) in the local solution space to look for the optimum solution or approximate optimal solutions. The experimental results show preliminarily that the scheme substantially improves the whole learning process approximation and generalization ability,and effectively promotes analog circuit fault diagnosis performance based on BPNN.展开更多
Because of the powerful mapping ability, back propagation neural network (BP-NN) has been employed in computer-aided product design (CAPD) to establish the property prediction model. The backward problem in CAPD is to...Because of the powerful mapping ability, back propagation neural network (BP-NN) has been employed in computer-aided product design (CAPD) to establish the property prediction model. The backward problem in CAPD is to search for the appropriate structure or composition of the product with desired property, which is an optimization problem. In this paper, a global optimization method of using the a BB algorithm to solve the backward problem is presented. In particular, a convex lower bounding function is constructed for the objective function formulated with BP-NN model, and the calculation of the key parameter a is implemented by recurring to the interval Hessian matrix of the objective function. Two case studies involving the design of dopamine β-hydroxylase (DβH) inhibitors and linear low density polyethylene (LLDPE) nano composites are investigated using the proposed method.展开更多
Phase pure ZrB2-SiC composite powders were prepared after 1 450℃/3 h via carbothermal reduction route,by using ZrSiO4,B2O3 and carbon as the raw materials.The influences of firing temperature as well as the type and ...Phase pure ZrB2-SiC composite powders were prepared after 1 450℃/3 h via carbothermal reduction route,by using ZrSiO4,B2O3 and carbon as the raw materials.The influences of firing temperature as well as the type and amount of additive on the phase composition of final products were detailedly investigated.The results indicated that the onset formation temperature of ZrB2-SiC was reduced to 1 400℃by the present conditions,and oxide additive(including CoSO4·7H2O,Y2O3 and TiO2)was effective in enhancing the decomposition of raw ZrSiO4,therefore accelerating the synthesis of ZrB2-SiC.Moreover,microstructural observation showed that the as-prepared ZrB2 and SiC respectively had well-defined hexagonal columnar and fibrous morphology.Furthermore,the methodology of back-propagation artificial neural networks(BP-ANNs)was adopted to establish a model for predicting the reaction extent(e g,the content of ZrB2-SiC in final product)in terms of various processing conditions.The results predicted by the as-established BP-ANNs model matched well with that of testing experiment(with a mean square error in 10^(-3) degree),verifying good effectiveness of the proposed strategy.展开更多
The hot deformation behavior of TI (18W-4Cr-1V) high-speed steel was investigated by means of continuous compression tests performed on Gleeble 1500 thermomechan- ical simulator in a wide range of tempemtures (950℃...The hot deformation behavior of TI (18W-4Cr-1V) high-speed steel was investigated by means of continuous compression tests performed on Gleeble 1500 thermomechan- ical simulator in a wide range of tempemtures (950℃-1150℃) with strain rotes of 0.001s-1-10s-1 and true strains of 0-0. 7. The flow stress at the above hot defor- mation conditions is predicted by using BP artificial neural network. The architecture of network includes there are three input parameters:strain rate,temperature T and true strain , and just one output parameter, the flow stress ,2 hidden layers are adopted, the first hidden layer includes 9 neurons and second 10 negroes. It has been verified that BP artificial neural network with 3-9-10-1 architecture can predict flow stress of high-speed steel during hot deformation very well. Compared with the prediction method of flow stress by using Zaped-Holloman parumeter and hyperbolic sine stress function, the prediction method by using BP artificial neurul network has higher efficiency and accuracy.展开更多
Thermal deformation error is one of the most important factors affecting the CNCs’ accuracy, so research is conducted on the temperature errors affecting CNCs’ machining accuracy;on the basis of analyzing the unpred...Thermal deformation error is one of the most important factors affecting the CNCs’ accuracy, so research is conducted on the temperature errors affecting CNCs’ machining accuracy;on the basis of analyzing the unpredictability and pre-maturing of the results of the genetic algorithm, as well as the slow speed of the training speed of the particle algorithm, a kind of Mind Evolutionary Algorithm optimized BP neural network featuring extremely strong global search capacity was proposed;type KVC850MA/2 five-axis CNC of Changzheng Lathe Factory was used as the research subject, and the Mind Evolutionary Algorithm optimized BP neural network algorithm was used for the establishment of the compensation model between temperature changes and the CNCs’ thermal deformation errors, as well as the realization method on hardware. The simulation results indicated that this method featured extremely high practical value.展开更多
基金supported by the National Natural Science Foundation of China Grant No.30771858Jiangsu Provincial Natural Science Foundation Grant No.BK2007229Priority Academic Program Development of Jiangsu Higher Education Institutions(PAPD)
文摘This study was aimed to explore the associations between the combined effects of several polymorphisms in the PPAR-γ and RXR-α gene and environmental factors with the risk of metabolic syndrome by back-error propaga- tion artificial neural network (BPANN). We established the model based on data gathered from metabolic syndrome patients (n = 1012) and normal controls (n = 1069) by BPANN. Mean impact value (MIV) for each input variable was calculated and the sequence of factors was sorted according to their absolute MIVs. Generalized multifactor dimensionality reduction (GMDR) confirmed a joint effect of PPAR-9" and RXR-a based on the results from BPANN. By BPANN analysis, the sequences according to the importance of metabolic syndrome risk fac- tors were in the order of body mass index (BMI), serum adiponectin, rs4240711, gender, rs4842194, family history of type 2 diabetes, rs2920502, physical activity, alcohol drinking, rs3856806, family history of hypertension, rs1045570, rs6537944, age, rs17817276, family history of hyperlipidemia, smoking, rs1801282 and rs3132291. However, no polymorphism was statistically significant in multiple logistic regression analysis. After controlling for environmental factors, A1, A2, B1 and B2 (rs4240711, rs4842194, rs2920502 and rs3856806) models were the best models (cross-validation consistency 10/10, P = 0.0107) with the GMDR method. In conclusion, the interaction of the PPAR-γ and RXR-α gene could play a role in susceptibility to metabolic syndrome. A more realistic model is obtained by using BPANN to screen out determinants of diseases of multiple etiologies like metabolic syndrome.
基金National Natural Science Foundation of China(No. 60474021)
文摘Various force disturbances influence the thrust force of linear motors when a linear motor (LM) is running. Among all of force disturbances, the force ripple is the dominant while a linear motor runs in low speed. In order to suppress the force ripple, back propagation(BP) neural network is proposed to learn the function of the force ripple of linear motors, and the acquisition method of training samples is proposed based on a disturbance observer. An off-line BP neural network is used mainly because of its high running efficiency and the real-time requirement of the servo control system of a linear motor. By using the function, the force ripple is on-line compensated according to the position of the LM. The experimental results show that the force ripple is effectively suppressed by the compensation of the BP neural network.
基金Natural Science Basic Research Plan in Shaanxi Province of China(No.2017JM5141)Shaanxi Provincial Education Department,China(No.17JK0334)+2 种基金Xi’an Polytechnic University Graduate Innovation Fund,China(No.chx2019083)Xi’an Science and Technology Bureau for Research Plan,China(No.201805030YD8CG14(5))Science Foundation for Doctorate Research of Xi’an Polytechnic University,China(No.BS1535)
文摘Aiming at the problem that back propagation(BP)neural network predicts the low accuracy rate of fluff fabric after fluffing process,a BP neural network model optimized by particle swarm optimization(PSO)algorithm is proposed.The sliced image is obtained by the principle of light-cutting imaging.The fluffy region of the adaptive image segmentation is extracted by the Freeman chain code principle.The upper edge coordinate information of the fabric is subjected to one-dimensional discrete wavelet decomposition to obtain high frequency information and low frequency information.After comparison and analysis,the BP neural network was trained by high frequency information,and the PSO algorithm was used to optimize the BP neural network.The optimized BP neural network has better weights and thresholds.The experimental results show that the accuracy of the optimized BP neural network after applying high-frequency information training is 97.96%,which is 3.79%higher than that of the unoptimized BP neural network,and has higher detection accuracy.
基金National Natural Science Foundation of China(No.61371024)Aviation Science Fund of China(No.2013ZD53051)+2 种基金Aerospace Technology Support Fund of Chinathe Industry-Academy-Research Project of AVIC,China(No.cxy2013XGD14)the Open Research Project of Guangdong Key Laboratory of Popular High Performance Computers/Shenzhen Key Laboratory of Service Computing and Applications,China
文摘Electronic components' reliability has become the key of the complex system mission execution. Analog circuit is an important part of electronic components. Its fault diagnosis is far more challenging than that of digital circuit. Simulations and applications have shown that the methods based on BP neural network are effective in analog circuit fault diagnosis. Aiming at the tolerance of analog circuit,a combinatorial optimization diagnosis scheme was proposed with back propagation( BP) neural network( BPNN).The main contributions of this scheme included two parts:( 1) the random tolerance samples were added into the nominal training samples to establish new training samples,which were used to train the BP neural network based diagnosis model;( 2) the initial weights of the BP neural network were optimized by genetic algorithm( GA) to avoid local minima,and the BP neural network was tuned with Levenberg-Marquardt algorithm( LMA) in the local solution space to look for the optimum solution or approximate optimal solutions. The experimental results show preliminarily that the scheme substantially improves the whole learning process approximation and generalization ability,and effectively promotes analog circuit fault diagnosis performance based on BPNN.
文摘Because of the powerful mapping ability, back propagation neural network (BP-NN) has been employed in computer-aided product design (CAPD) to establish the property prediction model. The backward problem in CAPD is to search for the appropriate structure or composition of the product with desired property, which is an optimization problem. In this paper, a global optimization method of using the a BB algorithm to solve the backward problem is presented. In particular, a convex lower bounding function is constructed for the objective function formulated with BP-NN model, and the calculation of the key parameter a is implemented by recurring to the interval Hessian matrix of the objective function. Two case studies involving the design of dopamine β-hydroxylase (DβH) inhibitors and linear low density polyethylene (LLDPE) nano composites are investigated using the proposed method.
基金Funded by National Natural Science Foundation of China(Nos.51502212,51672194 and 51472184)Hubei Province Natural Science Foundation of China(No.2018CFB760)+1 种基金Program for Innovative Teams of Outstanding Young and Middle-aged Researchers in the Higher Education Institutions of Hubei Province(No.T201602)Key Program of Natural Science Foundation of Hubei Province(No.2017CFA004)
文摘Phase pure ZrB2-SiC composite powders were prepared after 1 450℃/3 h via carbothermal reduction route,by using ZrSiO4,B2O3 and carbon as the raw materials.The influences of firing temperature as well as the type and amount of additive on the phase composition of final products were detailedly investigated.The results indicated that the onset formation temperature of ZrB2-SiC was reduced to 1 400℃by the present conditions,and oxide additive(including CoSO4·7H2O,Y2O3 and TiO2)was effective in enhancing the decomposition of raw ZrSiO4,therefore accelerating the synthesis of ZrB2-SiC.Moreover,microstructural observation showed that the as-prepared ZrB2 and SiC respectively had well-defined hexagonal columnar and fibrous morphology.Furthermore,the methodology of back-propagation artificial neural networks(BP-ANNs)was adopted to establish a model for predicting the reaction extent(e g,the content of ZrB2-SiC in final product)in terms of various processing conditions.The results predicted by the as-established BP-ANNs model matched well with that of testing experiment(with a mean square error in 10^(-3) degree),verifying good effectiveness of the proposed strategy.
文摘The hot deformation behavior of TI (18W-4Cr-1V) high-speed steel was investigated by means of continuous compression tests performed on Gleeble 1500 thermomechan- ical simulator in a wide range of tempemtures (950℃-1150℃) with strain rotes of 0.001s-1-10s-1 and true strains of 0-0. 7. The flow stress at the above hot defor- mation conditions is predicted by using BP artificial neural network. The architecture of network includes there are three input parameters:strain rate,temperature T and true strain , and just one output parameter, the flow stress ,2 hidden layers are adopted, the first hidden layer includes 9 neurons and second 10 negroes. It has been verified that BP artificial neural network with 3-9-10-1 architecture can predict flow stress of high-speed steel during hot deformation very well. Compared with the prediction method of flow stress by using Zaped-Holloman parumeter and hyperbolic sine stress function, the prediction method by using BP artificial neurul network has higher efficiency and accuracy.
文摘Thermal deformation error is one of the most important factors affecting the CNCs’ accuracy, so research is conducted on the temperature errors affecting CNCs’ machining accuracy;on the basis of analyzing the unpredictability and pre-maturing of the results of the genetic algorithm, as well as the slow speed of the training speed of the particle algorithm, a kind of Mind Evolutionary Algorithm optimized BP neural network featuring extremely strong global search capacity was proposed;type KVC850MA/2 five-axis CNC of Changzheng Lathe Factory was used as the research subject, and the Mind Evolutionary Algorithm optimized BP neural network algorithm was used for the establishment of the compensation model between temperature changes and the CNCs’ thermal deformation errors, as well as the realization method on hardware. The simulation results indicated that this method featured extremely high practical value.