This study was aimed to explore the associations between the combined effects of several polymorphisms in the PPAR-γ and RXR-α gene and environmental factors with the risk of metabolic syndrome by back-error propaga...This study was aimed to explore the associations between the combined effects of several polymorphisms in the PPAR-γ and RXR-α gene and environmental factors with the risk of metabolic syndrome by back-error propaga- tion artificial neural network (BPANN). We established the model based on data gathered from metabolic syndrome patients (n = 1012) and normal controls (n = 1069) by BPANN. Mean impact value (MIV) for each input variable was calculated and the sequence of factors was sorted according to their absolute MIVs. Generalized multifactor dimensionality reduction (GMDR) confirmed a joint effect of PPAR-9" and RXR-a based on the results from BPANN. By BPANN analysis, the sequences according to the importance of metabolic syndrome risk fac- tors were in the order of body mass index (BMI), serum adiponectin, rs4240711, gender, rs4842194, family history of type 2 diabetes, rs2920502, physical activity, alcohol drinking, rs3856806, family history of hypertension, rs1045570, rs6537944, age, rs17817276, family history of hyperlipidemia, smoking, rs1801282 and rs3132291. However, no polymorphism was statistically significant in multiple logistic regression analysis. After controlling for environmental factors, A1, A2, B1 and B2 (rs4240711, rs4842194, rs2920502 and rs3856806) models were the best models (cross-validation consistency 10/10, P = 0.0107) with the GMDR method. In conclusion, the interaction of the PPAR-γ and RXR-α gene could play a role in susceptibility to metabolic syndrome. A more realistic model is obtained by using BPANN to screen out determinants of diseases of multiple etiologies like metabolic syndrome.展开更多
The temperature characteristics of a silicon microgyroscope are studied, and the temperature compensation method of the silicon microgyroscope is proposed. First, an open-loop circuit is adopted to test the entire mic...The temperature characteristics of a silicon microgyroscope are studied, and the temperature compensation method of the silicon microgyroscope is proposed. First, an open-loop circuit is adopted to test the entire microgyroscope's resonant frequency and quality factor variations over temperature, and the zero bias changing trend over temperature is measured via a closed-loop circuit. Then, in order to alleviate the temperature effects on the performance of the microgyroscope, a kind of temperature compensated method based on the error back propagation(BP)neural network is proposed. By the Matlab simulation, the optimal temperature compensation model based on the BP neural network is well trained after four steps, and the objective error of the microgyroscope's zero bias can achieve 0.001 in full temperature range. By the experiment, the real time operation results of the compensation method demonstrate that the maximum zero bias of the microgyroscope can be decreased from 12.43 to 0.75(°)/s after compensation when the ambient temperature varies from -40 to 80℃, which greatly improves the zero bias stability performance of the microgyroscope.展开更多
In order to enhance the accuracy and reliability of wireless location under non-line-of-sight (NLOS) environments,a novel neural network (NN) location approach using the digital broadcasting signals is presented. ...In order to enhance the accuracy and reliability of wireless location under non-line-of-sight (NLOS) environments,a novel neural network (NN) location approach using the digital broadcasting signals is presented. By the learning ability of the NN and the closely approximate unknown function to any degree of desired accuracy,the input-output mapping relationship between coordinates and the measurement data of time of arrival (TOA) and time difference of arrival (TDOA) is established. A real-time learning algorithm based on the extended Kalman filter (EKF) is used to train the multilayer perceptron (MLP) network by treating the linkweights of a network as the states of the nonlinear dynamic system. Since the EKF-based learning algorithm approximately gives the minimum variance estimate of the linkweights,the convergence is improved in comparison with the backwards error propagation (BP) algorithm. Numerical results illustrate thatthe proposedalgorithmcanachieve enhanced accuracy,and the performance ofthe algorithmis betterthanthat of the BP-based NN algorithm and the least squares (LS) algorithm in the NLOS environments. Moreover,this location method does not depend on a particular distribution of the NLOS error and does not need line-of-sight ( LOS ) or NLOS identification.展开更多
The molecular structures of hydrocarbons in straight run gasoline were numerically coded. The nonlinear quantitative relationship(QSRR) between gas chromatography(GC) retention indices of the hydrocarbons and their m...The molecular structures of hydrocarbons in straight run gasoline were numerically coded. The nonlinear quantitative relationship(QSRR) between gas chromatography(GC) retention indices of the hydrocarbons and their molecular structures were established by using an error back propagation(BP) algorithm. The GC retention indices of 150 hydrocarbons were then predicted by removing 15 compounds(as a test set) and using the 135 remained molecules as a calibration set. Through this procedure, all the compounds in the whole data set were then predicted in groups of 15 compounds. The results obtained by BP with the correlation coefficient and the standard deviation 0 993 4 and 16 54, are satisfied.展开更多
The Artificial Neural Network (ANN) approach has been successfully used in many hydrological studies especially the rainfall-runoff modeling using continuous data. The present study examines its applicability to model...The Artificial Neural Network (ANN) approach has been successfully used in many hydrological studies especially the rainfall-runoff modeling using continuous data. The present study examines its applicability to model the event-based rainfall-runoff process. A case study has been done for Ajay river basin to develop event-based rainfall-runoff model for the basin to simulate the hourly runoff at Sarath gauging site. The results demonstrate that ANN models are able to provide a good representation of an event-based rainfall-runoff process. The two important parameters, when predicting a flood hydrograph, are the magnitude of the peak discharge and the time to peak discharge. The developed ANN models have been able to predict this information with great accuracy. This shows that ANNs can be very efficient in modeling an event-based rainfall-runoff process for determining the peak discharge and time to the peak discharge very accurately. This is important in water resources design and management applications, where peak discharge and time to peak discharge are important input展开更多
The corresponding corrected method is proposed for the INS ( INS-Inertial Navigation System ) accumulated error of large transport aircraft. System errors contain aircraft position error, altitude error and speed erro...The corresponding corrected method is proposed for the INS ( INS-Inertial Navigation System ) accumulated error of large transport aircraft. System errors contain aircraft position error, altitude error and speed error,one is increasing the accuracy of hardw are; the other is development of low cost softw are algorithms. Because of improving hardw are is more difficult in my country at present, developing softw are algorithms is essential w ay,w hich have been validated in my types of airplane. The combined heuristic algorithms ( ABPNN,Advanced Back-propagation neural netw orks algorithm and LSM -least square method) are presented,w hich incorporates the effects of flight region and measured terrain height data by radar and barometer. Based on this algorithm,the appropriate match region w as gotten by recognition of fiducial digital map in real time online. In process of w ork,the minimum of position error as a cost function and the constraint conditions are gave,the flight positions are recognized in real time and continuously,least sum of square is calculated based on LSM ,in other w ords,the optimized result is obtained. The simulation case demonstrate that the method is very successful,the correct rate of recognition is more 90 percent. In w ords,the algorithm presented is economical,validation and effective.展开更多
In the context of tower measured radiation datasets.following the correction principle meeting a diagnostic equation in data quality control and in terms of a technique for model construction on data and ANN(artificia...In the context of tower measured radiation datasets.following the correction principle meeting a diagnostic equation in data quality control and in terms of a technique for model construction on data and ANN(artificial neural network)retrieval for BP correction of radiation measurements with rough errors available,a BP model is presented.Evidence suggests that the developed model works well and is superior to a convenient multivariate linear regression model,indicating its wide applications.展开更多
基金supported by the National Natural Science Foundation of China Grant No.30771858Jiangsu Provincial Natural Science Foundation Grant No.BK2007229Priority Academic Program Development of Jiangsu Higher Education Institutions(PAPD)
文摘This study was aimed to explore the associations between the combined effects of several polymorphisms in the PPAR-γ and RXR-α gene and environmental factors with the risk of metabolic syndrome by back-error propaga- tion artificial neural network (BPANN). We established the model based on data gathered from metabolic syndrome patients (n = 1012) and normal controls (n = 1069) by BPANN. Mean impact value (MIV) for each input variable was calculated and the sequence of factors was sorted according to their absolute MIVs. Generalized multifactor dimensionality reduction (GMDR) confirmed a joint effect of PPAR-9" and RXR-a based on the results from BPANN. By BPANN analysis, the sequences according to the importance of metabolic syndrome risk fac- tors were in the order of body mass index (BMI), serum adiponectin, rs4240711, gender, rs4842194, family history of type 2 diabetes, rs2920502, physical activity, alcohol drinking, rs3856806, family history of hypertension, rs1045570, rs6537944, age, rs17817276, family history of hyperlipidemia, smoking, rs1801282 and rs3132291. However, no polymorphism was statistically significant in multiple logistic regression analysis. After controlling for environmental factors, A1, A2, B1 and B2 (rs4240711, rs4842194, rs2920502 and rs3856806) models were the best models (cross-validation consistency 10/10, P = 0.0107) with the GMDR method. In conclusion, the interaction of the PPAR-γ and RXR-α gene could play a role in susceptibility to metabolic syndrome. A more realistic model is obtained by using BPANN to screen out determinants of diseases of multiple etiologies like metabolic syndrome.
基金The National High Technology Research and Development Program of China (863 Program)(No.2002AA812038)the NationalNatural Science Foundation of China (No.60974116)
文摘The temperature characteristics of a silicon microgyroscope are studied, and the temperature compensation method of the silicon microgyroscope is proposed. First, an open-loop circuit is adopted to test the entire microgyroscope's resonant frequency and quality factor variations over temperature, and the zero bias changing trend over temperature is measured via a closed-loop circuit. Then, in order to alleviate the temperature effects on the performance of the microgyroscope, a kind of temperature compensated method based on the error back propagation(BP)neural network is proposed. By the Matlab simulation, the optimal temperature compensation model based on the BP neural network is well trained after four steps, and the objective error of the microgyroscope's zero bias can achieve 0.001 in full temperature range. By the experiment, the real time operation results of the compensation method demonstrate that the maximum zero bias of the microgyroscope can be decreased from 12.43 to 0.75(°)/s after compensation when the ambient temperature varies from -40 to 80℃, which greatly improves the zero bias stability performance of the microgyroscope.
基金The National High Technology Research and Development Program of China (863 Program) (No.2008AA01Z227)the Cultivatable Fund of the Key Scientific and Technical Innovation Project of Ministry of Education of China (No.706028)
文摘In order to enhance the accuracy and reliability of wireless location under non-line-of-sight (NLOS) environments,a novel neural network (NN) location approach using the digital broadcasting signals is presented. By the learning ability of the NN and the closely approximate unknown function to any degree of desired accuracy,the input-output mapping relationship between coordinates and the measurement data of time of arrival (TOA) and time difference of arrival (TDOA) is established. A real-time learning algorithm based on the extended Kalman filter (EKF) is used to train the multilayer perceptron (MLP) network by treating the linkweights of a network as the states of the nonlinear dynamic system. Since the EKF-based learning algorithm approximately gives the minimum variance estimate of the linkweights,the convergence is improved in comparison with the backwards error propagation (BP) algorithm. Numerical results illustrate thatthe proposedalgorithmcanachieve enhanced accuracy,and the performance ofthe algorithmis betterthanthat of the BP-based NN algorithm and the least squares (LS) algorithm in the NLOS environments. Moreover,this location method does not depend on a particular distribution of the NLOS error and does not need line-of-sight ( LOS ) or NLOS identification.
文摘The molecular structures of hydrocarbons in straight run gasoline were numerically coded. The nonlinear quantitative relationship(QSRR) between gas chromatography(GC) retention indices of the hydrocarbons and their molecular structures were established by using an error back propagation(BP) algorithm. The GC retention indices of 150 hydrocarbons were then predicted by removing 15 compounds(as a test set) and using the 135 remained molecules as a calibration set. Through this procedure, all the compounds in the whole data set were then predicted in groups of 15 compounds. The results obtained by BP with the correlation coefficient and the standard deviation 0 993 4 and 16 54, are satisfied.
文摘The Artificial Neural Network (ANN) approach has been successfully used in many hydrological studies especially the rainfall-runoff modeling using continuous data. The present study examines its applicability to model the event-based rainfall-runoff process. A case study has been done for Ajay river basin to develop event-based rainfall-runoff model for the basin to simulate the hourly runoff at Sarath gauging site. The results demonstrate that ANN models are able to provide a good representation of an event-based rainfall-runoff process. The two important parameters, when predicting a flood hydrograph, are the magnitude of the peak discharge and the time to peak discharge. The developed ANN models have been able to predict this information with great accuracy. This shows that ANNs can be very efficient in modeling an event-based rainfall-runoff process for determining the peak discharge and time to the peak discharge very accurately. This is important in water resources design and management applications, where peak discharge and time to peak discharge are important input
文摘The corresponding corrected method is proposed for the INS ( INS-Inertial Navigation System ) accumulated error of large transport aircraft. System errors contain aircraft position error, altitude error and speed error,one is increasing the accuracy of hardw are; the other is development of low cost softw are algorithms. Because of improving hardw are is more difficult in my country at present, developing softw are algorithms is essential w ay,w hich have been validated in my types of airplane. The combined heuristic algorithms ( ABPNN,Advanced Back-propagation neural netw orks algorithm and LSM -least square method) are presented,w hich incorporates the effects of flight region and measured terrain height data by radar and barometer. Based on this algorithm,the appropriate match region w as gotten by recognition of fiducial digital map in real time online. In process of w ork,the minimum of position error as a cost function and the constraint conditions are gave,the flight positions are recognized in real time and continuously,least sum of square is calculated based on LSM ,in other w ords,the optimized result is obtained. The simulation case demonstrate that the method is very successful,the correct rate of recognition is more 90 percent. In w ords,the algorithm presented is economical,validation and effective.
基金This work is supported jointly by the Project of Funds for University-Level Remarkable Teachers,Education Ministry of China by the Program of 2000 South-China Sea Flux Observations.
文摘In the context of tower measured radiation datasets.following the correction principle meeting a diagnostic equation in data quality control and in terms of a technique for model construction on data and ANN(artificial neural network)retrieval for BP correction of radiation measurements with rough errors available,a BP model is presented.Evidence suggests that the developed model works well and is superior to a convenient multivariate linear regression model,indicating its wide applications.