Endometriosis is a common benign gynecological disorder with an enigmatic etiology and pathogenesis.It affects approximately 10%women of reproductive age.Although its etiology and pathogenesis remain poorly understood...Endometriosis is a common benign gynecological disorder with an enigmatic etiology and pathogenesis.It affects approximately 10%women of reproductive age.Although its etiology and pathogenesis remain poorly understood,it is characterized by the elevated local production of estrogen in the endometriotic tissues.In this paper,we review the mechanisms of estrogen biosynthesis and its regulation in endometriosis.展开更多
基金supported in part by grants 81471434(SWG),81530040(SWG),81370695(XSL),and 81671436(XSL)the National Natural Science Foundation of China.
文摘Endometriosis is a common benign gynecological disorder with an enigmatic etiology and pathogenesis.It affects approximately 10%women of reproductive age.Although its etiology and pathogenesis remain poorly understood,it is characterized by the elevated local production of estrogen in the endometriotic tissues.In this paper,we review the mechanisms of estrogen biosynthesis and its regulation in endometriosis.
