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Exploration and Research on Textbook Quality Evaluation Index System Based on Engineering Major in Higher Education
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作者 Xiaoyang Yue Yanqiong Wu 《Journal of Contemporary Educational Research》 2024年第3期1-6,共6页
The report of the Chinese 20th National Congress put forward“strengthening the construction and management of textbooks”for the first time,which indicates the importance of textbook construction and highlights the v... The report of the Chinese 20th National Congress put forward“strengthening the construction and management of textbooks”for the first time,which indicates the importance of textbook construction and highlights the vital position of textbooks in the overall development of the country.From the perspective of textbook quality,and based on the research and analysis of the policy requirements and current evaluation indicators of higher education textbooks,this paper establishes the textbook quality evaluation index system composed of basic indicators and evaluation indicators.This system is based on the principles of science,comprehensiveness,operability,and target-oriented approach.It provides a relatively scientific,objective,and fair reference system for the management and evaluation of textbooks. 展开更多
关键词 Textbooks Evaluation index system Higher education Engineering major
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Preliminary Study on the Construction of Evaluation Index System for Clinical Medicine Postgraduates Based on Job Competency
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作者 Dandan Yuan Yunhong Liu Chao Wang 《Journal of Contemporary Educational Research》 2024年第11期123-129,共7页
Objective:To evaluate the practicality of constructing multiple evaluation index systems for postgraduates in clinical medicine professional degree based on job competency.Methods:The theoretical framework of the eval... Objective:To evaluate the practicality of constructing multiple evaluation index systems for postgraduates in clinical medicine professional degree based on job competency.Methods:The theoretical framework of the evaluation index system was initially developed using expert consultation,literature review,and other methods.20 survey experts were selected and consulted using the Delphi method to screen and evaluate the weights of multiple indicators.Data was then entered into a table to evaluate the practicality of the constructed indicators.Results:The questionnaire recovery rate of the first round of expert consultation was 92.50%,and the second round was 100.00%.The comparison between the two groups showed P<0.05.The authority level of the first round was 0.817,and the second round was 0.811.In the first round of coordination,the chi-square value of the first-level indicators was 0.498,and the chi-square value of the second-level indicators was 0.628.In the second round of coordination,the chi-square value of the first-level indicators was 0.573,and the chi-square value of the second-level indicators was 0.634.The comparison between the two rounds showed P<0.05.The evaluation index system included 2 first-level indicators,5 second-level indicators,and 31 third-level indicators.Conclusion:Constructing an evaluation index system based on job competency is highly scientific,with a reasonable construction process and high practical value. 展开更多
关键词 Job competency Clinical medicine profession POSTGRADUATES Evaluation index system
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Construction of an Evaluation Index System for Innovation and Entrepreneurship Education in Vocational Colleges from Students’Perspective
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作者 Aihong Wang Yueming Zhan +1 位作者 Wendie Wang Liqun Xu 《Journal of Contemporary Educational Research》 2024年第9期10-16,共7页
Innovation and entrepreneurship education is an essential content in the current teaching of colleges and universities and an important driving force to promote students’employment.Currently,colleges and universities... Innovation and entrepreneurship education is an essential content in the current teaching of colleges and universities and an important driving force to promote students’employment.Currently,colleges and universities continue to strengthen the innovation of innovation and entrepreneurship teaching,and the construction of the evaluation system of innovation and entrepreneurship education is lagging.The evaluation system is an important evaluation standard for innovation and entrepreneurship teaching and the basis for educational innovation,which is also a critical part of teaching that requires attention.This paper takes the construction of the evaluation index system of innovation and entrepreneurship education in vocational colleges as the research goal and understands the function of innovation and entrepreneurship evaluation as well as the evaluation principle through the literature analysis method.It also analyzes the evaluation index system of innovation and entrepreneurship teaching from students’perspective to provide an effective reference for the implementation of innovation and entrepreneurship education in higher vocational colleges. 展开更多
关键词 Student perspective Vocational college Innovation and entrepreneurship education Evaluation index system
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Development of an Information-Based Leadership Evaluation Index System for School Management Teams:A Comprehensive Approach
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作者 Wei Li Fang Liu 《Journal of Contemporary Educational Research》 2024年第4期35-40,共6页
In the context of educational informatization reform,there are many uncertain factors in the process of education development.To optimize the educational environment so that it can be effectively combined with informa... In the context of educational informatization reform,there are many uncertain factors in the process of education development.To optimize the educational environment so that it can be effectively combined with information technology,teachers need to change their teaching ideas,strengthen the school’s own adaptability to informatization,and promote the development of informatization construction in schools.As a branch of information leadership,the management team should establish an evaluation index system for information leadership in order to ensure the construction of school informatization,so as to provide a boost for the integration of school resources and information technology.Based on the overview and connotation of information-based leadership of the management team,this paper explores the construction of an evaluation index system of information-based leadership of the school management team,aiming to provide references for the research of relevant personnel in the future. 展开更多
关键词 School management team Information-based leadership Evaluation index system
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Actuality and underlying mechanisms of systemic immuneinflammation index and geriatric nutritional risk index prognostic value in hepatocellular carcinoma
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作者 Konstantin Y Tchilikidi 《World Journal of Gastrointestinal Surgery》 SCIE 2024年第2期260-265,共6页
This editorial contains comments on the article“Correlation between preoperative systemic immune inflammation index,nutritional risk index,and prognosis of radical resection of liver cancer”in a recent issue of the ... This editorial contains comments on the article“Correlation between preoperative systemic immune inflammation index,nutritional risk index,and prognosis of radical resection of liver cancer”in a recent issue of the World Journal of Gastrointestinal Surgery.It pointed out the actuality and importance of the article and focused primarily on the underlying mechanisms making the systemic immuneinflammation index(SII)and geriatric nutritional risk index(GNRI)prediction features valuable.There are few publications on both SII and GNRI together in hepatocellular carcinoma(HCC)and patient prognosis after radical surgery.Neutrophils release cytokines,chemokines,and enzymes,degrade extracellular matrix,reduce cell adhesion,and create conditions for tumor cell invasion.Neutrophils promote the adhesion of tumor cells to endothelial cells,through physical anchoring.That results in the migration of tumor cells.Pro-angiogenic factors from platelets enhance tumor angiogenesis to meet tumor cell supply needs.Platelets can form a protective film on the surface of tumor cells.This allows avoiding blood flow damage as well as immune system attack.It also induces the epithelial-mesenchymal transformation of tumor cells that is critical for invasiveness.High SII is also associated with macro-and microvascular invasion and increased numbers of circulating tumor cells.A high GNRI was associated with significantly better progression-free and overall survival.HCC patients are a very special population that requires increased attention.SII and GNRI have significant survival prediction value in both palliative treatment and radical surgery settings.The underlying mechanisms of their possible predictive properties lie in the field of essential cancer features.Those features provide tumor nutrition,growth,and distribution throughout the body,such as vascular invasion.On the other hand,they are tied to the possibility of patients to resist tumor progression and development of complications in both postoperative and cancer-related settings.The article is of considerable interest.It would be helpful to continue the study follow-up to 2 years and longer.External validation of the data is needed. 展开更多
关键词 systemic immune-inflammation index Geriatric nutritional risk index Radical surgery Transarterial chemoembolization Hepatocellular carcinoma Prognosis
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Systemic immune-inflammation index,neutrophilto-lymphocyte ratio,and platelet-to-lymphocyte ratio in patients with type 2 diabetes at different stages of diabetic retinopathy
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作者 Ying Gao Rong-Xin Lu +6 位作者 Yun Tang Xin-Yi Yang Hu Meng Chang-Lin Zhao Yi-Lu Chen Feng Yan Qian Cao 《International Journal of Ophthalmology(English edition)》 SCIE CAS 2024年第5期877-882,共6页
AIM:To investigate systemic immune-inflammation index(SII),neutrophil-to-lymphocyte ratio(NLR),and plateletto-lymphocyte ratio(PLR)levels in patients with type 2 diabetes at different stages of diabetic retinopathy(DR... AIM:To investigate systemic immune-inflammation index(SII),neutrophil-to-lymphocyte ratio(NLR),and plateletto-lymphocyte ratio(PLR)levels in patients with type 2 diabetes at different stages of diabetic retinopathy(DR).METHODS:This retrospective study included 141 patients with type 2 diabetes mellitus(DM):45 without diabetic retinopathy(NDR),47 with non-proliferative diabetic retinopathy(NPDR),and 49 with proliferative diabetic retinopathy(PDR).Complete blood counts were obtained,and NLR,PLR,and SII were calculated.The study analysed the ability of inflammatory markers to predict DR using receiver operating characteristic(ROC)curves.The relationships between DR stages and SII,PLR,and NLP were assessed using multivariate logistic regression.RESULTS:The average NLR,PLR,and SII were higher in the PDR group than in the NPDR group(P=0.011,0.043,0.009,respectively);higher in the NPDR group than in the NDR group(P<0.001 for all);and higher in the PDR group than in the NDR group(P<0.001 for all).In the ROC curve analysis,the NLR,PLR,and SII were significant predictors of DR(P<0.001 for all).The highest area under the curve(AUC)was for the PLR(0.929 for PLR,0.925 for SII,and 0.821 for NLR).Multivariate regression analysis indicated that NLR,PLR,and SII were statistically significantly positive and independent predictors for the DR stages in patients with DM[odds ratio(OR)=1.122,95%confidence interval(CI):0.200–2.043,P<0.05;OR=0.038,95%CI:0.018–0.058,P<0.05;OR=0.007,95%CI:0.001–0.01,P<0.05,respectively).CONCLUSION:The NLR,PLR,and SII may be used as predictors of DR. 展开更多
关键词 diabetic retinopathy neutrophil-tolymphocyte ratio platelet-to-lymphocyte ratio systemic immune-inflammation index
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Research Progress of Systemic Immune Inflammatory Index in Prostate Cancer
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作者 Zhiwei Zhao Shaoping Cheng 《Journal of Biosciences and Medicines》 2024年第10期339-348,共10页
Prostate cancer has gradually risen to become the second most common cancer threatening men’s health, and prostate-specific antigen (PSA), as the main screening indicator for prostate cancer, has the defects of low s... Prostate cancer has gradually risen to become the second most common cancer threatening men’s health, and prostate-specific antigen (PSA), as the main screening indicator for prostate cancer, has the defects of low specificity and insufficient diagnostic efficacy. As a novel inflammatory index based on neutrophil, lymphocyte and platelet counts, the systemic immune-inflammation index (SII) has recently become a more powerful biomarker for predicting the occurrence and progression of various malignancies. SII reflects the systemic inflammatory response of prostate cancer patients in a more balanced manner, and has higher predictive value than neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR). High SII values are often associated with cancer progression and poor prognosis. This article reviews the research progress of SII in prostate cancer, in order to provide guidance for clinical practice. 展开更多
关键词 Prostate Cancer systemic Immune Inflammatory index Prostate-Specific Antigen
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Systemic inflammatory response index is a predictor of prognosis in gastric cancer patients: Retrospective cohort and meta-analysis
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作者 Jing-Yao Ren Meng Xu +5 位作者 Xiang-Dong Niu Shi-Xun Ma Ya-Jun Jiao Da Wang Miao Yu Hui Cai 《World Journal of Gastrointestinal Surgery》 SCIE 2024年第2期382-395,共14页
BACKGROUND The systemic inflammatory response index(SIRI)has been demonstrated to make a significant difference in assessing the prognosis of patients with different solid neoplasms.However,research is needed to ascer... BACKGROUND The systemic inflammatory response index(SIRI)has been demonstrated to make a significant difference in assessing the prognosis of patients with different solid neoplasms.However,research is needed to ascertain the accuracy and reliability of applying the SIRI to patients who undergo robotic radical gastric cancer sur-gery.AIM To validate the applicability of the SIRI in assessing the survival of gastric cancer patients and evaluate the clinical contribution of preoperative SIRI levels to predicting long-term tumor outcomes in patients,who received robotic radical gastric cancer surgery.METHODS Initially,an exhaustive retrieval was performed in the PubMed,the Cochrane Library,EMBASE,Web of Science,and Scopus databases to identify relevant studies.Subsequently,a meta-analysis was executed on 6 cohort studies iden-tifying the value of the SIRI in assessing the survival of gastric cancer patients.Additionally,the clinical data of 161 patients undergoing robotic radical gastric cancer surgery were retrospectively analyzed to evaluate their clinicopathological characteristics and relevant laboratory indicators.The association between preoperative SIRI levels and 5-year overall survival(OS)and disease-free survival(DFS)was assessed.RESULTS The findings demonstrated an extensive connection between SIRI values and the outcome of patients with gastric cancer.Preoperative SIRI levels were identified as an independent hazard feature for both OS and DFS among those who received robotic surgery for gastric cancer.SIRI levels in gastric cancer patients were observed to be associated with the presence of comorbidities,T-stage,carcinoembryonic antigen levels,the development of early serious postoperative complications,and the rate of lymph node metastasis.CONCLUSION SIRI values are correlated with adverse in the gastric cancer population and have the potential to be utilized in predicting long-term oncological survival in patients who undergo robotic radical gastric cancer surgery. 展开更多
关键词 systemic inflammatory response index PROGNOSIS Gastric cancer COMPLICATIONS META-ANALYSIS
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Impact of body mass index on adverse kidney events in diabetes mellitus patients: A systematic-review and meta-analysis
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作者 Jing-Fang Wan Yan Chen +2 位作者 Tian-Hua Yao Ya-Zhou Wu Huan-Zi Dai 《World Journal of Clinical Cases》 SCIE 2024年第3期538-550,共13页
BACKGROUND The incidence of chronic kidney disease among patients with diabetes mellitus(DM)remains a global concern.Long-term obesity is known to possibly influence the development of type 2 diabetes mellitus.However... BACKGROUND The incidence of chronic kidney disease among patients with diabetes mellitus(DM)remains a global concern.Long-term obesity is known to possibly influence the development of type 2 diabetes mellitus.However,no previous meta-analysis has assessed the effects of body mass index(BMI)on adverse kidney events in patients with DM.AIM To determine the impact of BMI on adverse kidney events in patients with DM.METHODS A systematic literature search was performed on the PubMed,ISI Web of Science,Scopus,Ovid,Google Scholar,EMBASE,and BMJ databases.We included trials with the following characteristics:(1)Type of study:Prospective,retrospective,randomized,and non-randomized in design;(2)participants:Restricted to patients with DM aged≥18 years;(3)intervention:No intervention;and(4)kidney adverse events:Onset of diabetic kidney disease[estimated glomerular filtration rate(eGFR)of<60 mL/min/1.73 m2 and/or microalbuminuria value of≥30 mg/g Cr],serum creatinine increase of more than double the baseline or end-stage renal disease(eGFR<15 mL/min/1.73 m2 or dialysis),or death.RESULTS Overall,11 studies involving 801 patients with DM were included.High BMI(≥25 kg/m2)was significantly associated with higher blood pressure(BP)[systolic BP by 0.20,95%confidence interval(CI):0.15–0.25,P<0.00001;diastolic BP by 0.21 mmHg,95%CI:0.04–0.37,P=0.010],serum albumin,triglycerides[standard mean difference(SMD)=0.35,95%CI:0.29–0.41,P<0.00001],low-density lipoprotein(SMD=0.12,95%CI:0.04–0.20,P=0.030),and lower high-density lipoprotein(SMD=–0.36,95%CI:–0.51 to–0.21,P<0.00001)in patients with DM compared with those with low BMIs(<25 kg/m2).Our analysis showed that high BMI was associated with a higher risk ratio of adverse kidney events than low BMI(RR:1.22,95%CI:1.01–1.43,P=0.036).CONCLUSION The present analysis suggested that high BMI was a risk factor for adverse kidney events in patients with DM. 展开更多
关键词 Obesity Body mass index Diabetes mellitus Adverse kidney events systematic-review META-ANALYSIS
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Prognostic nutritional index in predicting survival of patients with gastric or gastroesophageal junction adenocarcinoma: A systematic review
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作者 Stylianos Fiflis Grigorios Christodoulidis +6 位作者 Menelaos Papakonstantinou Alexandros Giakoustidis Stergos Koukias Paraskevi Roussos Marina Nektaria Kouliou Konstantinos Eleftherios Koumarelas Dimitrios Giakoustidis 《World Journal of Gastrointestinal Oncology》 SCIE 2024年第2期514-526,共13页
BACKGROUND Gastric cancer is the third most common cause of cancer related death worldwide.Surgery with or without chemotherapy is the most common approach with curative intent;however,the prognosis is poor as mortali... BACKGROUND Gastric cancer is the third most common cause of cancer related death worldwide.Surgery with or without chemotherapy is the most common approach with curative intent;however,the prognosis is poor as mortality rates remain high.Several indexes have been proposed in the past few years in order to estimate the survival of patients undergoing gastrectomy.The preoperative nutritional status of gastric cancer patients has recently gained attention as a factor that could affect the postoperative course and various indexes have been developed.The aim of this systematic review was to assess the role of the prognostic nutritional index(PNI)in predicting the survival of patients with gastric or gastroesophageal adenocarcinoma who underwent gastrectomy with curative intent.AIM To investigate the role of PNI in predicting the survival of patients with gastric or gastroesophageal junction adenocarcinoma.METHODS A thorough literature search of PubMed and the Cochrane library was performed for studies comparing the overall survival(OS)of patients with gastric or gastroesophageal cancer after surgical resection depending on the preoperative PNI value.The PRISMA algorithm was used in the screening process and finally 16 studies were included in this systematic review.The review protocol was registered in the International Prospective Register of Systematic Reviews(PRO) RESULTS Sixteen studies involving 14551 patients with gastric or esophagogastric junction adenocarcinoma undergoing open or laparoscopic or robotic gastrectomy with or without adjuvant chemotherapy were included in this systematic review.The patients were divided into high-and low-PNI groups according to cut-off values that were set according to previous reports or by using receiver operating characteristic curve analysis in each individual study.The 5-year OS of patients in the low-PNI groups ranged between 39%and 70.6%,while in the high-PNI groups,it ranged between 54.9%and 95.8%.In most of the included studies,patients with high preoperative PNI showed statistically significant better OS than the low PNI groups.In multivariate analyses,low PNI was repeatedly recognised as an independent prognostic factor for poor survival.CONCLUSION According to the present study,low preoperative PNI seems to be an indicator of poor OS of patients undergoing gastrectomy for gastric or gastroesophageal cancer. 展开更多
关键词 Prognostic nutritional index Gastric adenocarcinoma Gastroesophageal junction cancer PROGNOSIS Overall survival
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Preoperative systemic inflammatory response index as a prognostic marker for distal cholangiocarcinoma after pancreatoduodenectomy
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作者 Wen-Hui Zhang Yu Zhao +3 位作者 Cheng-Run Zhang Jin-Can Huang Shao-Cheng Lyu Ren Lang 《World Journal of Gastrointestinal Surgery》 SCIE 2024年第9期2910-2924,共15页
BACKGROUND The relationship between preoperative inflammation status and tumorigenesis as well as tumor progression is widely acknowledged.AIM To assess the prognostic significance of preoperative inflammatory biomark... BACKGROUND The relationship between preoperative inflammation status and tumorigenesis as well as tumor progression is widely acknowledged.AIM To assess the prognostic significance of preoperative inflammatory biomarkers in patients with distal cholangiocarcinoma(dCCA)who underwent pancreat-oduodenectomy(PD).METHODS This single-center study included 216 patients with dCCA after PD between January 1,2011,and December 31,2022.The individuals were categorized into two sets based on their systemic inflammatory response index(SIRI)levels:A low SIRI group(SIRI<1.5,n=123)and a high SIRI group(SIRI≥1.5,n=93).Inflam-matory biomarkers were evaluated for predictive accuracy using receiver operating characteristic curves.Both univariate and multivariate Cox proportional hazards analyses were performed to estimate SIRI for overall survival(OS)and recurrence-free survival(RFS).RESULTS The study included a total of 216 patients,with 58.3%being male and a mean age of 65.6±9.6 years.123 patients were in the low SIRI group and 93 were in the high SIRI group after PD for dCCA.SIRI had an area under the curve value of 0.674 for diagnosing dCCA,showing better performance than other inflammatory biomarkers.Multivariate analysis indicated that having a SIRI greater than 1.5 independently increased the risk of dCCA following PD,leading to lower OS[hazard ratios(HR)=1.868,P=0.006]and RFS(HR=0.949,P<0.001).Additionally,survival analysis indicated a significantly better prognosis for patients in the low SIRI group(P<0.001).CONCLUSION It is determined that a high SIRI before surgery is a significant risk factor for dCCA after PD. 展开更多
关键词 Distal cholangiocarcinoma PANCREATODUODENECTOMY BIOMARKER systemic inflammatory response index Prognosis
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Predictive value of systemic immunity index for sepsis in low-medium risk community-acquired pneumonia
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作者 CHAI Dou-dou WANG Xiao-miao XING Bo 《Journal of Hainan Medical University》 CAS 2024年第2期26-32,共7页
Objective:To assess the predictive value of systemic immune inflammation index(SII)for sepsis in low-and medium-risk community-acquired pneumonia.Methods:A total of 589 elderly patients with low-and medium-risk commun... Objective:To assess the predictive value of systemic immune inflammation index(SII)for sepsis in low-and medium-risk community-acquired pneumonia.Methods:A total of 589 elderly patients with low-and medium-risk community-acquired pneumonia admitted to the Emergency Department of the Second Affiliated Hospital of Hainan Medical University from January 2020 to January 2023 were included as the research subjects,and the general information and laboratory test results of the patients were collected,and the optimal cut-off value of continuous variables for predicting sepsis in elderly patients with low-and medium-risk community-acquired pneumonia was determined by plotting the receiver work characteristic(ROC)curve,which was converted into dichotomous variables and univariate and multivariate logistic Regression analysis of the influencing factors of sepsis in elderly patients with low-and medium-risk community-acquired pneumonia.Based on this,a nomogram model is constructed to predict the risk of sepsis.The differentiation,consistency and accuracy of the model were verified by calibration curve and subject operating characteristic(ROC)curve,and the clinical utility of the model was determined by decision curve analysis.Results:A total of 589 elderly patients with low-and intermediate-risk community-acquired pneumonia were included in this study,of which 96(16.30%)developed sepsis.There were significant differences in age,diabetes mellitus and chronic obstructive pulmonary disease,Lac,PCT,SII and other indexes between sepsis and non-sepsis groups(P<0.05).Logistics regression analysis showed that age,diabetes mellitus and chronic obstructive pulmonary disease,Lac,and SII were independent risk factors for sepsis in elderly patients with low-and medium-risk community-acquired pneumonia.The nomogram prediction model was used to verify the results,and the AUC was 0.826(95%CI:0.780-0.872),and the calibration curve tended to the ideal curve with good accuracy.The decision curve shows that when the threshold of the model is between 0.10~0.78,the model has the advantage of clinical benefit.Conclusion:The nomogram prediction model constructed based on SII to predict sepsis in elderly patients with low-and medium-risk community-acquired pneumonia has good accuracy,which can predict the occurrence of sepsis early,help early identification of high-risk groups and timely intervention,and thus improve the prognosis of patients. 展开更多
关键词 Senior citizen systemic immunoinflammation index Community-acquired pneumonia SEPSIS Nomogram model
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Systemic Inflammation Response Index and weight loss as prognostic factors in metastatic pancreatic cancer: A concept study from the PANTHEIA-SEOM trial
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作者 Vilma Pacheco-Barcia Sara Custodio-Cabello +7 位作者 Fatima Carrasco-Valero Magda Palka-Kotlowska Axel Mariño-Mendez Alberto Carmona-Bayonas Javier Gallego A J Muñoz Martín Paula Jimenez-Fonseca Luis Cabezon-Gutierrez 《World Journal of Gastrointestinal Oncology》 SCIE 2024年第2期386-397,共12页
BACKGROUND The prognostic value of the Systemic Inflammation Response Index(SIRI)in advanced pancreatic cancer is recognized,but its correlation with patients´nutritional status and outcomes remains unexplored.AI... BACKGROUND The prognostic value of the Systemic Inflammation Response Index(SIRI)in advanced pancreatic cancer is recognized,but its correlation with patients´nutritional status and outcomes remains unexplored.AIM To study the prognostic significance of SIRI and weight loss in metastatic pancreatic cancer.METHODS The PANTHEIA-Spanish Society of Medical Oncology(SEOM)study is a multicentric(16 Spanish hospitals),observational,longitudinal,non-interventional initiative,promoted by the SEOM Real World-Evidence work group.This pilot study sought to analyze the association between weight loss and inflammatory status as defined by SIRI.The cohort stems from a proof-of-concept pilot study conducted at one of the coordinating centers.Patients with pathologically confirmed metastatic pancreatic adenocarcinoma,treated from January 2020 to January 2023,were included.The index was calculated using the product of neutrophil and monocyte counts,divided by lymphocyte counts,obtained within 15 days before initiation chemotherapy.This study evaluated associations between overall survival(OS),SIRI and weight loss.RESULTS A total of 50 patients were included.66%of these patients were male and the median age was 66 years.Metastasis sites:36%liver,12%peritoneal carcinomatosis,10%lung,and 42%multiple locations.Regarding the first line palliative chemotherapy treatments:50%received gemcitabine plus nab-paclitaxel;28%,modified fluorouracil,leucovorin,irinotecan and oxaliplatin,and 16%were administered gemcitabine.42%had a weight loss>5%in the three months(mo)preceding diagnosis.21 patients with a SIRI≥2.3×10^(3)/L exhibited a trend towards a lower median OS compared to those with a SIRI<2.3×10^(3)/L(4 vs 18 mo;P<0.000).Among 21 patients with>5%weight loss before diagnosis,the median OS was 6 mo,in contrast to 19 mo for those who did not experience such weight loss(P=0.003).Patients with a weight loss>5%showed higher SIRI levels.This difference was statistically significant(P<0.000).For patients with a SIRI<2.3×10^(3)/L,those who did not lose>5%of their weight had an OS of 20 mo,compared to 11 mo for those who did(P<0.001).No association was found between carbohydrate antigen 19-9 levels≥1000 U/mL and weight loss.CONCLUSION A higher SIRI was correlated with decreased survival rates in patients with metastatic pancreatic cancer and associated with weight loss.An elevated SIRI is suggested as a predictor of survival,emphasizing the need for prospective validation in the upcoming PANTHEIA-SEOM study. 展开更多
关键词 Pancreatic cancer NUTRITION Prognostic factor INFLAMMATION Advanced cancer systemic inflammatory response index Weight loss
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Systemic immune-inflammation index combined with pediatric appendicitis score in assessing the severity and prognosis for paediatric appendicitis
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作者 Li-Ming Guo Zhi-Hui Jiang Hong-Zhen Liu 《World Journal of Gastrointestinal Surgery》 SCIE 2024年第8期2565-2573,共9页
BACKGROUND Pediatric appendicitis is a common cause of abdominal pain in children and is recognized as a significant surgical emergency.A prompt and accurate diagnosis is essential to prevent complications such as per... BACKGROUND Pediatric appendicitis is a common cause of abdominal pain in children and is recognized as a significant surgical emergency.A prompt and accurate diagnosis is essential to prevent complications such as perforation and peritonitis.AIM To investigate the predictive value of the systemic immune-inflammation index(SII)combined with the pediatric appendicitis score(PAS)for the assessment of disease severity and surgical outcomes in children aged 5 years and older with appendicitis.METHODS Clinical data of 104 children diagnosed with acute appendicitis were analyzed.The participants were categorized into the acute appendicitis group and chronic appendicitis group based on disease presentation and further stratified into the good prognosis group and poor prognosis group based on prognosis.The SII and PAS were measured,and a joint model using the combined SII and PAS was constructed to predict disease severity and surgical outcomes.RESULTS Significant differences were observed in the SII and PAS parameters between the acute appendicitis group and chronic appendicitis group.Correlation analysis showed associations among the SII,PAS,and disease severity,with the combined SII and PAS model demonstrating significant predictive value for assessing disease severity[aera under the curve(AUC)=0.914]and predicting surgical outcomes(AUC=0.857)in children aged 5 years and older with appendicitis.CONCLUSION The study findings support the potential of integrating the SII with the PAS for assessing disease severity and predicting surgical outcomes in pediatric appendicitis,indicating the clinical utility of the combined SII and PAS model in guiding clinical decision-making and optimizing surgical management strategies for pediatric patients with appendicitis. 展开更多
关键词 systemic immune-inflammation index Pediatric appendicitis score Disease severity Surgical outcomes Risk factor Logistic regression Receiver operating characteristic analysis
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Establishment of an index system for evaluating outstanding biomedical scientists for science foundation of Shanghai 被引量:1
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作者 张寓景 陈馨 任旭峰 《Journal of Medical Colleges of PLA(China)》 CAS 2007年第3期191-194,共4页
Objective:To establish a scientific,objective and applicable index system for evaluating out- standing biomedical scientists for science foundation of Shanghai.Methods:According to the principal in- dices that have be... Objective:To establish a scientific,objective and applicable index system for evaluating out- standing biomedical scientists for science foundation of Shanghai.Methods:According to the principal in- dices that have been used in the developed countries for evaluating their talented personnel and the reality of our country,an index system was set up to evaluate the outstanding biomedical scientists for Shanghai science foundation.The following parameters were used to simplify the indices.,correlation coefficient, multiple correlation coefficient,partial correlation coefficient,creditability,and discriminatory power. And analytic hierarchy process was used to determine the weights of each index.Results and Conclusions: The established index system is scientific and applicable;it is helpful for cultivating and evaluating out- standing biomedical scientists. 展开更多
关键词 science foundation biomedical scientists correlation coefficient degree of confidence degree of differentiation pairwise comparison matrix WEIGHT index system
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Research on the Index System of Old Neighborhood Renovation Based on Green Building Evaluation Standard
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作者 Yufei Que 《Journal of Architectural Research and Development》 2024年第3期140-146,共7页
With the advancement of the transformation,the contradiction between the residents’demand for a better living environment and the convenience of living in the settlements comes to the fore.Effective identification,or... With the advancement of the transformation,the contradiction between the residents’demand for a better living environment and the convenience of living in the settlements comes to the fore.Effective identification,organic integration,timely adoption,and correct decision-making for the transformation of old neighborhoods are pressing issues in the transformation of old neighborhoods.Therefore,this paper takes the green building evaluation standards of various countries as the research basis and support for the construction of the transformation strategy of old neighborhoods.Through the collection and comparative analysis of the indicators of green building evaluation standards,the index system of transformation is formed,and it also provides a certain foundation for the subsequent related research. 展开更多
关键词 Old neighborhoods Green building evaluation standards RENOVATION CRITERIA
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Constructing Index System for Evaluating Work Level in Rural Endowment Insurance
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作者 ZHAO Zhigang WANG Yalin 《Journal of Northeast Agricultural University(English Edition)》 CAS 2008年第3期90-96,共7页
This paper used fuzzy math principles, analyzed different aspects of the work of the current rural endowment insurance and formed the indices to assess the work level of the rural endowment insurance. After selecting ... This paper used fuzzy math principles, analyzed different aspects of the work of the current rural endowment insurance and formed the indices to assess the work level of the rural endowment insurance. After selecting the indices of the work level scientificly, constructed the index system to evaluate the work level of the rural endowment insurance and the index system was expressed in the form of math equation. In this way, an objective standard used to evaluate the work level of rural endowment insurance was establised. 展开更多
关键词 rural endowment insurance work level index system
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Effectiveness of Combined Application of Shock Index and Early Warning Scoring System in Patients with Acute Gastrointestinal Hemorrhage
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作者 Dalei Chen 《Journal of Clinical and Nursing Research》 2024年第7期342-348,共7页
Objective:To explore the effect of the combined application of the Shock Index(SI)and the Early Warning Score(EWS)in patients with acute gastrointestinal bleeding.Methods:Seventy patients with acute gastrointestinal b... Objective:To explore the effect of the combined application of the Shock Index(SI)and the Early Warning Score(EWS)in patients with acute gastrointestinal bleeding.Methods:Seventy patients with acute gastrointestinal bleeding admitted to a hospital from June 2022 to May 2024 were selected and randomly divided into two groups:the control group and the observation group,with 35 patients in each group.The control group received conventional emergency care measures,while the observation group received SI combined with NEWS emergency care measures.The treatment effects in both groups were compared.Results:The observation group had shorter waiting times for consultation(4.45±1.59 minutes),intravenous access establishment(6.79±2.52 minutes),hemostasis time(4.41±1.52 hours),and hospital stays(8.39±2.13 days)compared to the control group,which had times of 5.46±1.34 minutes,8.41±2.16 minutes,5.16±1.47 hours,and 10.26±2.98 days,respectively.The differences were statistically significant(P<0.05).Before management,there were no significant differences in the levels of hemoglobin,prealbumin,and serum protein between the two groups(P>0.05).However,after systematic emergency management,the serum indexes in both groups significantly improved,with the observation group showing greater improvement than the control group,and these differences were statistically significant(P<0.05).In the observation group,only one case of cardiovascular complications occurred during the rescue period,with an incidence rate of 2.86%.In contrast,the control group experienced eight cases of complications,including hemorrhagic shock,anemia,multi-organ failure,cardiovascular complications,and gastrointestinal rebleeding,with an incidence rate of 22.85%.The difference between the groups was statistically significant(P<0.05).Conclusion:The application of SI combined with EWS emergency care measures in patients with acute gastrointestinal hemorrhage can effectively improve serum indexes,shorten resuscitation time and hospital stay,and reduce the risk of complications such as hemorrhagic shock,anemia,infection,multi-organ failure,cardiovascular complications,acute renal failure,and gastrointestinal rebleeding.This approach has positive clinical application value. 展开更多
关键词 Acute gastrointestinal bleeding Shock index Early Warning Score Clinical assessment Prognosis optimization
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Discussion and Application of Planning EIA Index System in the Industrial Development Region Based on Low Carbon Economy 被引量:1
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作者 熊鸿斌 王萍 +1 位作者 金潇 项芳 《Meteorological and Environmental Research》 CAS 2010年第12期86-90,共5页
Aimed at the low carbon economy and the characteristics of planning EIA in the industrial development region,the planning EIA index system which merged with the low carbon economy concept in the industrial development... Aimed at the low carbon economy and the characteristics of planning EIA in the industrial development region,the planning EIA index system which merged with the low carbon economy concept in the industrial development region was established.The construction planning of national eco-industrial park in Hefei High-tech Industrial Development Zone was comprehensively evaluated by using the gray correlation method.The evaluation results of considering and without considering the low carbon index were contrasted and were verified by using the improved entropy method.The results showed that the regional sustainable development index constantly rose,and the planning was reasonable.Moreover,the suggestions were also put forward to tackle the problems. 展开更多
关键词 Planning EIA in the industrial development region Low carbon economy Evaluation index system China
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Study on the evaluation index system and evaluation method for self-elevating drilling unit design 被引量:1
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作者 王运龙 纪卓尚 《Journal of Marine Science and Application》 2009年第1期46-52,共7页
In the process of designing self-elevating drilling unit, it is important, yet complicated, to use comparison and filtering to select the optimum scheme from the feasible ones. In this research, an index system and me... In the process of designing self-elevating drilling unit, it is important, yet complicated, to use comparison and filtering to select the optimum scheme from the feasible ones. In this research, an index system and methodology for the evaluation of self-elevating drilling unit was proposed. Based on this, a multi-objective combinatorial optimization model was developed, using the improved grey relation Analysis (GRA), in which the analytic hierarchy process (AHP) was used to determine the weights of the evaluating indices. It considered the connections within the indices, reflecting the objective nature of things, and also considered the subjective interests of ship owners and the needs of designers. The evaluation index system and evaluation method can be used in the selection of an optimal scheme and advanced assessment. A case study shows the index system and evaluation method are scientific, reasonable, and easy to put into practice. At the same time, such an evaluation index system and evaluation method will be helpful for making decisions for other mobile platforms. 展开更多
关键词 self-elevating drilling unit evaluation index system evaluation method grey relation analysis (GRA) analytic hierarchy process (AHP)
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