Botswana students excel at schools built with China’s grants While the coronavirus pandemic has disrupted education across the world,the impact of school closures has been much worse in developing countries where mos...Botswana students excel at schools built with China’s grants While the coronavirus pandemic has disrupted education across the world,the impact of school closures has been much worse in developing countries where most pupils lack access to quality education.展开更多
Chinese doctors in Rwanda are transforming healthcare services by providing specialised medical care to people with limited means Agnes Nyiramivumbi looked worried and was in deep pain as she sat down on the hospital ...Chinese doctors in Rwanda are transforming healthcare services by providing specialised medical care to people with limited means Agnes Nyiramivumbi looked worried and was in deep pain as she sat down on the hospital chair waiting to be attended by a doctor.“I have endured pain in my left leg for over seven years and the pain has reached the left arm.展开更多
The meandering channel deposit of the upper member of Neogene Guantao Formation in Shengli Chengdao extra-shallow sea oilfield is characterized by rapid change in sedimentary facies.In addition,affected by surface tid...The meandering channel deposit of the upper member of Neogene Guantao Formation in Shengli Chengdao extra-shallow sea oilfield is characterized by rapid change in sedimentary facies.In addition,affected by surface tides and sea water reverberation,the double sensor seismic data processed by conventional methods has low signal-to-noise ratio and low resolution,and thus cannot meet the needs of seismic description and oil-bearing fluid identification of thin reservoirs less than 10 meters thick in this area.The two-step high resolution frequency bandwidth expanding processing technology was used to improve the signal-to-noise ratio and resolution of the seismic data,as a result,the dominant frequency of the seismic data was enhanced from 30 Hz to 50 Hz,and the sand body thickness resolution was enhanced from 10 m to 6 m.On the basis of fine layer control by seismic data,three types of seismic facies models,floodplain,natural levee and point bar,were defined,and the intelligent horizon-facies controlled recognition technology was worked out,which had a prediction error of reservoir thickness of less than 1.5 m.Clearly,the description accuracy of meandering channel sand bodies has been improved.The probability semi-quantitative oiliness identification method of fluid by prestack multi-parameters has been worked out by integrating Poisson’s ratio,fluid factor,product of Lame parameter and density,and other prestack elastic parameters,and the method has a coincidence rate of fluid identification of more than 90%,providing solid technical support for the exploration and development of thin reservoirs in Shengli Chengdao extra-shallow sea oilfield,which is expected to provide reference for the exploration and development of similar oilfields in China.展开更多
文摘Botswana students excel at schools built with China’s grants While the coronavirus pandemic has disrupted education across the world,the impact of school closures has been much worse in developing countries where most pupils lack access to quality education.
文摘Chinese doctors in Rwanda are transforming healthcare services by providing specialised medical care to people with limited means Agnes Nyiramivumbi looked worried and was in deep pain as she sat down on the hospital chair waiting to be attended by a doctor.“I have endured pain in my left leg for over seven years and the pain has reached the left arm.
基金Supported by the China National Science and Technology Major Project(2016zx05006)Sinopec Program for Science and Technology Development(P15156,P15159)。
文摘The meandering channel deposit of the upper member of Neogene Guantao Formation in Shengli Chengdao extra-shallow sea oilfield is characterized by rapid change in sedimentary facies.In addition,affected by surface tides and sea water reverberation,the double sensor seismic data processed by conventional methods has low signal-to-noise ratio and low resolution,and thus cannot meet the needs of seismic description and oil-bearing fluid identification of thin reservoirs less than 10 meters thick in this area.The two-step high resolution frequency bandwidth expanding processing technology was used to improve the signal-to-noise ratio and resolution of the seismic data,as a result,the dominant frequency of the seismic data was enhanced from 30 Hz to 50 Hz,and the sand body thickness resolution was enhanced from 10 m to 6 m.On the basis of fine layer control by seismic data,three types of seismic facies models,floodplain,natural levee and point bar,were defined,and the intelligent horizon-facies controlled recognition technology was worked out,which had a prediction error of reservoir thickness of less than 1.5 m.Clearly,the description accuracy of meandering channel sand bodies has been improved.The probability semi-quantitative oiliness identification method of fluid by prestack multi-parameters has been worked out by integrating Poisson’s ratio,fluid factor,product of Lame parameter and density,and other prestack elastic parameters,and the method has a coincidence rate of fluid identification of more than 90%,providing solid technical support for the exploration and development of thin reservoirs in Shengli Chengdao extra-shallow sea oilfield,which is expected to provide reference for the exploration and development of similar oilfields in China.
文摘背景与目的中国易瑞沙(吉非替尼、ZD1839)扩大用药(EAP)项目开始于2001年,旨在为标准治疗失败后或不能耐受化疗的晚期非小细胞肺癌(non-small cell lung cancer,NSCLC)患者提供吉非替尼单药治疗。本研究主要评估仍在EAP组长期生存者的生活质量、肿瘤控制情况、服药安全性、临床特点及基因测定。次要目标为探讨长期生存者的临床特征。方法这是一项描述性观察研究,数据收集依据流行病学研究方法。对于仍在EAP组中的患者,数据将采用横断面调查的方法;对于已从EAP组中退出的长期生存者和快速进展者,数据以回顾性方式收集。结果在EAP数据库中共筛选出符合条件的患者934例,其中59例为服用吉非替尼>3年的长期生存者,包括25例仍在EAP组,34例已退出EAP组,875例为快速进展者。59例长期生存者来自中国的15个临床中心。仍在EAP组的长期生存者,中位肺癌治疗功能评价量表(functional assessment of cancer therapy-lung,FACT-L)、试验结果系数(trial outcome index,TOI)和肺癌量表(lung cancer subscale,LCS)分值分别为64.5、37和12.5,91.6%患者的体力状态(performance status,PS)为0分-1分,客观有效率、疾病控制率和中位有效持续时间分别为37.5%、87.5%和68个月。在59例长期生存者中,没有发现严重或新的不良反应;其中<65岁者68.5%,腺癌81.4%,女性55.9%,从不吸烟者71%。与快速进展者比较,长期生存者中女性比例稍高(P=0.02)。本研究收集了3例患者的组织标本,其中1例EGFR突变阳性;2例Ki-67蛋白表达阳性,这2例患者生存期都超过73个月。同时收集了22例血浆标本,1例EGFR突变阳性。结论部分晚期NSCLC应用吉非替尼治疗可获3年以上长期生存,并为长期生存者提供了良好的生活质量、满意的疗效和药物耐受性。
