AIM: To clarify the effectiveness of CO2 insufflation in potentially difficult colonoscopy cases, particularly in relation to the experience level of colonoscopists. METHODS: One hundred twenty potentially difficult...AIM: To clarify the effectiveness of CO2 insufflation in potentially difficult colonoscopy cases, particularly in relation to the experience level of colonoscopists. METHODS: One hundred twenty potentially difficult cases were included in this study, which involved females with a low body mass index and patients with earlier abdominal and/or pelvic open surgery or previously diagnosed left-side colon diverticulosis. Patients receiving colonoscopy examinations without sedation using a pediatric variable-stiffness colonoscope were divided into two groups based on either CO2 or standard air insuffiation. Both insufflation procedures were also evaluated according to the experience level of the respective colonoscopists who were divided into an experienced colonoscopist (EC) group and a less experienced colonoscopist (LEC) group. Study measurements included a 100-mm visual analogue scale (VAS) for patient pain during and after colonoscopy examinations, in addition to insertion to the cecum and withdrawal times. RESULTS: Examination times did not differ, however, VAS scores in the CO2 group were significantly better than in the air group (P〈 0.001, two-way ANOVA) from immediately after the procedure and up to 2 h later. There were no significant differences between either insufflation method in the EC group (P = 0.29), however, VAS scores for CO2 insufflation were significantly better than air insufflation in the LEC group (P = 0.023) immediately after colonoscopies and up to 4 h afterwards. CONCLUSION: CO2 insufflation reduced patient pain after colonoscopy in potentially difficult cases when performed by LECs.展开更多
Several scholars have reported high mental health problems among adolescents with Human Immunodeficiency Virus (HIV) globally. However, little is known about the mental health of this peculiar group of young people in...Several scholars have reported high mental health problems among adolescents with Human Immunodeficiency Virus (HIV) globally. However, little is known about the mental health of this peculiar group of young people in Choma district. This study aimed to determine the mental health problems experienced by HIV positive adolescents in Choma District. Using the Strengths and Difficulties Questionnaire (SDQ), data were obtained from 103 HIV positive adolescents receiving treatment at Choma General Hospital plus a corresponding number of parents/care givers. Information about mental health services was obtained qualitatively from 10 nurses working in the mental health unit and the Antiretroviral (ART) clinic. The results showed that more than three quarters of the adolescents had mental health problems. Of this number, 57.3 percent had multiple mental health problems: predominantly emotional and peer problems. The study also found a statistically significant relationship between level of stigma and presence of mental health problems (X2 = 1.123, P = 0.003). In conclusion, the study demonstrated that multiple mental health problems particularly emotional and peer problems are prevalent among adolescents with HIV/AIDS yet are most often undiagnosed. In addition, adolescents with high levels of internalized stigma are more likely to have multiple mental health problems. The findings suggest the need to integrate psychiatric services into routine care of HIV infected adolescents, routine screening for mental health problems and provision of continued professional development among nurses managing these patients.展开更多
From November 26 to December 3,2023,Professor Wu Dong of the International Wushu Development Research Center of the China Wushu School,Beijing Sport University went to Tanzania and Mauritius to give lectures.During th...From November 26 to December 3,2023,Professor Wu Dong of the International Wushu Development Research Center of the China Wushu School,Beijing Sport University went to Tanzania and Mauritius to give lectures.During the 8-day China Story Taijiquan lecture series,the people of Tanzania and Mauritius have got close to Taijiquan,understood the mystery of Taijiquan and experienced its effects on health.展开更多
CHINA Promising Drone Industry China’s drone industry has experienced rapid development,with a massive surge in the number of newly registered unmanned aerial vehicles(UAVs)in H1 of 2024.
Objective:To explore the most effective herbal combinations commonly used by highly experienced Chinese medicine(CM) physicians for the treatment of insomnia.Methods:We collected and analyzed data related to insom...Objective:To explore the most effective herbal combinations commonly used by highly experienced Chinese medicine(CM) physicians for the treatment of insomnia.Methods:We collected and analyzed data related to insomnia treatment from the clinics of 7 highly experienced CM physicians in Beijing.The sample included 162 patients and 460 consultations in total.Patient outcomes,such as sleep quality and sleep time per day,were manually collected from the medical records by trained CM clinicians.Three data mining methods,support vector machine(SVM),logistic regression and decision tree,and multifactor dimensionality reduction(MDR),were used to determine and confirm the herbal combinations that resulted in positive outcomes in patients suffering from insomnia.Results:Results show that MDR is the most efficient method to predict the effective herbal combinations.Using the MDR model,we identified several combinations of herbs with 100%positive outcomes,such as stir-fried spine date seed,Szechwan lovage rhizome,and prepared thinleaf milkwort root;white peony root,golden thread,and stir-fried spine date seed;and Asiatic cornelian cherry fruit with fresh rehmannia.Conclusions:Results indicate that herbal combinations are effective treatments for patients with insomnia compared with individual herbs.It is also shown that MDR is a potent data mining method to identify the herbal combination with high rates of positive outcome.展开更多
This study investigates experienced teachers’resistance in an era of neoliberalism in Macao.The narratives of three experienced teachers are examined under a post-structuralist framework.The findings indicate that th...This study investigates experienced teachers’resistance in an era of neoliberalism in Macao.The narratives of three experienced teachers are examined under a post-structuralist framework.The findings indicate that the traditional Chinese Confucian ideology of education guides the experienced teachers’professional practice and offers them an alternative subject position to inhabit that makes it possible for them to establish a critical distance from the prevailing norms imposed by the hegemony of neoliberalism.Such a distance allows the experienced teachers to observe,to think otherwise and consequently to live out a different teaching life and to reassemble their identity around an empowered notion of self.The study concludes that the Confucian ideology of education has contributed to the transformation of the contemporary discursive context of Macao by promising a future for education,a future with a revisioned future rather than a neoliberal incorporation of the past.展开更多
The following was a keynote speech of the CAAM at an annual conference on the auto parts industry. 1.The first stage:to introduce the advanced technologies to localize car parts. In the mid 1980's,the auto industr...The following was a keynote speech of the CAAM at an annual conference on the auto parts industry. 1.The first stage:to introduce the advanced technologies to localize car parts. In the mid 1980's,the auto industry began introducing the car and展开更多
Prolonged exposure to coal dust may lead to various lung diseases, especially coal workers’ pneumoconiosis(CWP)[1]. Developed countries such as the United States experienced a resurgence of pneumoconiosis in the earl...Prolonged exposure to coal dust may lead to various lung diseases, especially coal workers’ pneumoconiosis(CWP)[1]. Developed countries such as the United States experienced a resurgence of pneumoconiosis in the early 20t h century[2], and this phenomenon has become even more critical in developing countries[3]such as China and India.展开更多
To explore the relationship between rear-end crash risk and its influencing factors, on-road experiments were conducted for measuring the individual vehicle trajectory data associated with novice and experienced drive...To explore the relationship between rear-end crash risk and its influencing factors, on-road experiments were conducted for measuring the individual vehicle trajectory data associated with novice and experienced drivers. The rear-end crash potential probability based on the time to collision was proposed to represent the interpretation of rear-end crash risk.One-way analysis of variance was applied to compare the rearend crash risks for novice and experienced drivers. The rearend crash risk models for novice and experienced drivers were respectively developed to identify the effects of contributing factors on the driver rear-end crash risk. Also, the cumulative residual method was used to examine the goodness-of-fit of models. The results show that there is a significant difference in rear-end risk between the novice and experienced drivers.For the novice drivers, three risk factors including the traffic volume, the number of lanes and gender are found to significantly impact on the rear-end crash risk, while significant impact factors for experienced drivers are the vehicle speed and traffic volume. The rear-end crash risk models perform well based on the existing limited data samples.展开更多
China has experienced dramatic changes in food consumption patterns over the last three decades. However, there are different opinions regarding the future trends in consumption. By adopting the well-developed partial...China has experienced dramatic changes in food consumption patterns over the last three decades. However, there are different opinions regarding the future trends in consumption. By adopting the well-developed partial equilibrium model-China Agricultural Policy Simulation Model(CAPSi M), the demand for livestock products and the main feed crops over 2011–2030 is predicted and analyzed. It is found that China's per capita consumption of livestock products will continue to rise during this period, even though its growth rate will slow down gradually. Meanwhile, the expansion of livestock production will pose great challenges for feed supply in China. More accurately, China will be confronted with feed security rather than grain security in the future.展开更多
Using the empirical recipe of Wang Pengfei (a very experienced TCM doctor) as the main treatment, the authors treated 80 children with peptic ulcer by means of promoting blood circulation, removing blood stasis as wel...Using the empirical recipe of Wang Pengfei (a very experienced TCM doctor) as the main treatment, the authors treated 80 children with peptic ulcer by means of promoting blood circulation, removing blood stasis as well as regulating the flow of qi, alleviating pain, tonify-ing the stomach and reinforcing the spleen. Measures for hemostasis, correction of anemia and other general treatment were also taken. After 8 weeks of treatment, a total effective rate of 92.5% was obtained.展开更多
The objective of this research was to assess the characteristics of seismic induced damage and the deformation patterns of pre-stressed cement-grouted cables that are used for rock slope stabilization projects subject...The objective of this research was to assess the characteristics of seismic induced damage and the deformation patterns of pre-stressed cement-grouted cables that are used for rock slope stabilization projects subjected to quasi-static cyclic loading.The experimental configuration includes the installation of 15 pre-stressed cables in a slope model made of concrete blocks(theoretically rigid rock mass) on top of a pre-existing sliding surface.The study showed that:(i) The pre-stressed cables exhibited great seismic performance.Rapid displacement of the model blocks was observed after the complete loss of the initial pre-stress load under continued applied cyclic loads and exceedance of the state of equilibrium,which implies the higher the initial pre-stress load,the better the seismic performance of the rock anchor;(ii) The failure of the pre-stressed cables was due to fracture at the connection of the tendons and cable heads under cyclic loading.The sequence of failure had a distinct pattern.Failure was first observed at the upper row of cables,which experienced the most severe damage,including the ejection of cable heads.No evidence of de-bonding was observed during the cyclic loading;(iii) The stress distribution of the bond length for pre-stressed cables was highly non-uniform.High stress concentrations were observed at both the fixed end and the free end of the bond length both before and immediately after the state of equilibrium is exceeded.The results obtained can be used to evaluate the overall performance of pre-stressed rock anchors subject to seismic loading and their potential as rockfall prevention and stabilization measures.展开更多
This study aimed to examine the clinical efficacy of minimally invasive percutaneous catheter drainage(PCD) versus open laparotomy with temporary closure in the treatment of abdominal compartment syndrome(ACS) in ...This study aimed to examine the clinical efficacy of minimally invasive percutaneous catheter drainage(PCD) versus open laparotomy with temporary closure in the treatment of abdominal compartment syndrome(ACS) in patients with early-stage severe acute pancreatitis(SAP). Clinical data of 212 patients who underwent PCD and 61 patients who were given open laparotomy with temporary closure in our hospital over the last 10-year period were retrospectively analyzed, and outcomes were compared, including total and post-decompression intensive care unit(ICU) and hospital stays, physiological data, organ dysfunction, complications, and mortality. The results showed that the organ dysfunction scores were similar between the PCD and open laparotomy groups 72 h after decompression. In the PCD group, 134 of 212(63.2%) patients required postoperative ICU support versus 60 of 61(98.4%) in the open laparotomy group(P〈0.001). Additionally, 87(41.0%) PCD patients experienced complications as compared to 49 of 61(80.3%) in the open laparotomy group(P〈0.001). There were 40(18.9%) and 32(52.5%) deaths, respectively, in the PCD and open laparotomy groups(P〈0.001). In conclusion, minimally invasive PCD is superior to open laparotomy with temporary closure, with fewer complications and deaths occurring in PCD group.展开更多
We describe an observational study of clinical, virologic and drug resistance profiles in HIV-positive antiretroviral adherent subjects with stable low level viremia (LLV) 50 - 1000 copies/mL for more than 12 months. ...We describe an observational study of clinical, virologic and drug resistance profiles in HIV-positive antiretroviral adherent subjects with stable low level viremia (LLV) 50 - 1000 copies/mL for more than 12 months. Subjects were followed from time of first detectable viral load (VL). In total, 102 episodes of LLV were detected among 80 individuals. The median (mean, range) HIV copy number at genotyping was 250 (486, - 3900) copies/mL after 14 (17.9, 0 - 58) months of LLV. Few patients maintained LLV for the entire 9 years period of observation, with half (52%) experiencing viremic progression following a stable period of LLV either spontaneously or after treatment interruption or failed regimen intensification. In the setting of prolonged periods of sustained LLV, mean duration 22 (range 8 - 106) months, drug resistance (DR) was almost universal. Resistance to ≥1 on-treatment drugs was defined in 97% of specimens and DR to all drugs in the treatment regimen in over half of all patients. Evolution of DR mutations during the period of LLV was observed in 20/28 (71%) subjects with specimens available for follow-up testing. This evolution was associated with viremic progression to levels >1000 copies/mL (p = 0.03). Our data suggest that DR present in patients with LLV is likely to impact long term clinical outcomes, highlighting the importance of optimizing techniques to detect the presence of drug resistant HIV in the setting of LLV and the need for larger prospective studies to assess the emergence of DR in the setting of sustained LLV and the impact of this DR on treatment outcomes.展开更多
Visiting the sauna regularly could reduce the risk of dementia,a new study has found.Scientists at the University of East Finland followed more than 2,000middle-aged men for 20 years to find out what factors influence...Visiting the sauna regularly could reduce the risk of dementia,a new study has found.Scientists at the University of East Finland followed more than 2,000middle-aged men for 20 years to find out what factors influenced how many developed cognitive^1 problems in later life.展开更多
Acupuncture at a single point is a spe-cial feature in the treatment of acute symp-toms for its simplicity and effectiveness.Theauthor experienced many cases of acuteepigastric pain treated with acupuncture at asingle...Acupuncture at a single point is a spe-cial feature in the treatment of acute symp-toms for its simplicity and effectiveness.Theauthor experienced many cases of acuteepigastric pain treated with acupuncture at asingle acupoint with satisfactory results.Pain in the elderly is most often of展开更多
The development of tropical karst in Guilin could be dated back to middle Triassic, i.e. up to 240 million years, and the incipient karst landform was formed from the middle Triassic to the early Jurassic, a period wi...The development of tropical karst in Guilin could be dated back to middle Triassic, i.e. up to 240 million years, and the incipient karst landform was formed from the middle Triassic to the early Jurassic, a period with intensive karstification. Later, the karst in the area has experienced three major periods, that is, the weak period from the middle Jurassic to the late Cretaceous; the intensive period in the Tertiary which was significant to the formation of the old Li River; and the third period lasts the Quaternary period which has completed the typical tropical karst landform. Some ideas about the effect of paleo lake water to the formation of the tropical karst and the ages of caves on different levels in Guilin have been put forward.展开更多
Cotton has been identified as a crop with promising potential in Namibia.As such,cotton variety evaluation trials have been conducted for yield,fiber qualities,resistance to diseases and pests。
基金Supported by The Japanese Foundation for Research and Promotion of Endoscopy (JFE)
文摘AIM: To clarify the effectiveness of CO2 insufflation in potentially difficult colonoscopy cases, particularly in relation to the experience level of colonoscopists. METHODS: One hundred twenty potentially difficult cases were included in this study, which involved females with a low body mass index and patients with earlier abdominal and/or pelvic open surgery or previously diagnosed left-side colon diverticulosis. Patients receiving colonoscopy examinations without sedation using a pediatric variable-stiffness colonoscope were divided into two groups based on either CO2 or standard air insuffiation. Both insufflation procedures were also evaluated according to the experience level of the respective colonoscopists who were divided into an experienced colonoscopist (EC) group and a less experienced colonoscopist (LEC) group. Study measurements included a 100-mm visual analogue scale (VAS) for patient pain during and after colonoscopy examinations, in addition to insertion to the cecum and withdrawal times. RESULTS: Examination times did not differ, however, VAS scores in the CO2 group were significantly better than in the air group (P〈 0.001, two-way ANOVA) from immediately after the procedure and up to 2 h later. There were no significant differences between either insufflation method in the EC group (P = 0.29), however, VAS scores for CO2 insufflation were significantly better than air insufflation in the LEC group (P = 0.023) immediately after colonoscopies and up to 4 h afterwards. CONCLUSION: CO2 insufflation reduced patient pain after colonoscopy in potentially difficult cases when performed by LECs.
文摘Several scholars have reported high mental health problems among adolescents with Human Immunodeficiency Virus (HIV) globally. However, little is known about the mental health of this peculiar group of young people in Choma district. This study aimed to determine the mental health problems experienced by HIV positive adolescents in Choma District. Using the Strengths and Difficulties Questionnaire (SDQ), data were obtained from 103 HIV positive adolescents receiving treatment at Choma General Hospital plus a corresponding number of parents/care givers. Information about mental health services was obtained qualitatively from 10 nurses working in the mental health unit and the Antiretroviral (ART) clinic. The results showed that more than three quarters of the adolescents had mental health problems. Of this number, 57.3 percent had multiple mental health problems: predominantly emotional and peer problems. The study also found a statistically significant relationship between level of stigma and presence of mental health problems (X2 = 1.123, P = 0.003). In conclusion, the study demonstrated that multiple mental health problems particularly emotional and peer problems are prevalent among adolescents with HIV/AIDS yet are most often undiagnosed. In addition, adolescents with high levels of internalized stigma are more likely to have multiple mental health problems. The findings suggest the need to integrate psychiatric services into routine care of HIV infected adolescents, routine screening for mental health problems and provision of continued professional development among nurses managing these patients.
文摘From November 26 to December 3,2023,Professor Wu Dong of the International Wushu Development Research Center of the China Wushu School,Beijing Sport University went to Tanzania and Mauritius to give lectures.During the 8-day China Story Taijiquan lecture series,the people of Tanzania and Mauritius have got close to Taijiquan,understood the mystery of Taijiquan and experienced its effects on health.
文摘CHINA Promising Drone Industry China’s drone industry has experienced rapid development,with a massive surge in the number of newly registered unmanned aerial vehicles(UAVs)in H1 of 2024.
基金Supported by Programmes of Beijing Municipal S&T Commission,China(No.D08050703020803, D08050703020804)China Key Technologies R&D Programme (No.2007BA110B06-01) National S&T Major Project(No. 2009ZX09301-005-010)
文摘Objective:To explore the most effective herbal combinations commonly used by highly experienced Chinese medicine(CM) physicians for the treatment of insomnia.Methods:We collected and analyzed data related to insomnia treatment from the clinics of 7 highly experienced CM physicians in Beijing.The sample included 162 patients and 460 consultations in total.Patient outcomes,such as sleep quality and sleep time per day,were manually collected from the medical records by trained CM clinicians.Three data mining methods,support vector machine(SVM),logistic regression and decision tree,and multifactor dimensionality reduction(MDR),were used to determine and confirm the herbal combinations that resulted in positive outcomes in patients suffering from insomnia.Results:Results show that MDR is the most efficient method to predict the effective herbal combinations.Using the MDR model,we identified several combinations of herbs with 100%positive outcomes,such as stir-fried spine date seed,Szechwan lovage rhizome,and prepared thinleaf milkwort root;white peony root,golden thread,and stir-fried spine date seed;and Asiatic cornelian cherry fruit with fresh rehmannia.Conclusions:Results indicate that herbal combinations are effective treatments for patients with insomnia compared with individual herbs.It is also shown that MDR is a potent data mining method to identify the herbal combination with high rates of positive outcome.
文摘This study investigates experienced teachers’resistance in an era of neoliberalism in Macao.The narratives of three experienced teachers are examined under a post-structuralist framework.The findings indicate that the traditional Chinese Confucian ideology of education guides the experienced teachers’professional practice and offers them an alternative subject position to inhabit that makes it possible for them to establish a critical distance from the prevailing norms imposed by the hegemony of neoliberalism.Such a distance allows the experienced teachers to observe,to think otherwise and consequently to live out a different teaching life and to reassemble their identity around an empowered notion of self.The study concludes that the Confucian ideology of education has contributed to the transformation of the contemporary discursive context of Macao by promising a future for education,a future with a revisioned future rather than a neoliberal incorporation of the past.
文摘The following was a keynote speech of the CAAM at an annual conference on the auto parts industry. 1.The first stage:to introduce the advanced technologies to localize car parts. In the mid 1980's,the auto industry began introducing the car and
基金supported by the Chinese Academy of Medical Sciences (CAMS) Innovation Fund for Medical Sciences(CIFM)[no. 2016-12M-3-001]the China Medical Board “Strengthen Capacity of Study and Application on Burden of Disease in Health Care System of China–Establishment and Development of Chinese Burden of Disease Research and Dissemination Center”[no. 15-208]。
文摘Prolonged exposure to coal dust may lead to various lung diseases, especially coal workers’ pneumoconiosis(CWP)[1]. Developed countries such as the United States experienced a resurgence of pneumoconiosis in the early 20t h century[2], and this phenomenon has become even more critical in developing countries[3]such as China and India.
基金The National Natural Science Foundation of China(No.51478110)
文摘To explore the relationship between rear-end crash risk and its influencing factors, on-road experiments were conducted for measuring the individual vehicle trajectory data associated with novice and experienced drivers. The rear-end crash potential probability based on the time to collision was proposed to represent the interpretation of rear-end crash risk.One-way analysis of variance was applied to compare the rearend crash risks for novice and experienced drivers. The rearend crash risk models for novice and experienced drivers were respectively developed to identify the effects of contributing factors on the driver rear-end crash risk. Also, the cumulative residual method was used to examine the goodness-of-fit of models. The results show that there is a significant difference in rear-end risk between the novice and experienced drivers.For the novice drivers, three risk factors including the traffic volume, the number of lanes and gender are found to significantly impact on the rear-end crash risk, while significant impact factors for experienced drivers are the vehicle speed and traffic volume. The rear-end crash risk models perform well based on the existing limited data samples.
基金support from the National Natural Science Foundation of China(71373255)the Institute of Geographic Sciences and Natural Resources Research,Chinese Academy of Sciences(2012RC102)the National Maize Industrial Technical System,China(nycytx-02)
文摘China has experienced dramatic changes in food consumption patterns over the last three decades. However, there are different opinions regarding the future trends in consumption. By adopting the well-developed partial equilibrium model-China Agricultural Policy Simulation Model(CAPSi M), the demand for livestock products and the main feed crops over 2011–2030 is predicted and analyzed. It is found that China's per capita consumption of livestock products will continue to rise during this period, even though its growth rate will slow down gradually. Meanwhile, the expansion of livestock production will pose great challenges for feed supply in China. More accurately, China will be confronted with feed security rather than grain security in the future.
文摘Using the empirical recipe of Wang Pengfei (a very experienced TCM doctor) as the main treatment, the authors treated 80 children with peptic ulcer by means of promoting blood circulation, removing blood stasis as well as regulating the flow of qi, alleviating pain, tonify-ing the stomach and reinforcing the spleen. Measures for hemostasis, correction of anemia and other general treatment were also taken. After 8 weeks of treatment, a total effective rate of 92.5% was obtained.
基金financially supported by the National Basic Research Program of China (973 Program) (Grant No.2013CB733202)the National Natural Science Foundation of China (Grant No.41102191)+1 种基金the State Key Laboratory of Geohazard Prevention and Geoenvironment Protection (Chengdu University of Technology) (Grant No.SKLGP2011Z019)the National Natural Science Foundation of China (Grant No.11670589)
文摘The objective of this research was to assess the characteristics of seismic induced damage and the deformation patterns of pre-stressed cement-grouted cables that are used for rock slope stabilization projects subjected to quasi-static cyclic loading.The experimental configuration includes the installation of 15 pre-stressed cables in a slope model made of concrete blocks(theoretically rigid rock mass) on top of a pre-existing sliding surface.The study showed that:(i) The pre-stressed cables exhibited great seismic performance.Rapid displacement of the model blocks was observed after the complete loss of the initial pre-stress load under continued applied cyclic loads and exceedance of the state of equilibrium,which implies the higher the initial pre-stress load,the better the seismic performance of the rock anchor;(ii) The failure of the pre-stressed cables was due to fracture at the connection of the tendons and cable heads under cyclic loading.The sequence of failure had a distinct pattern.Failure was first observed at the upper row of cables,which experienced the most severe damage,including the ejection of cable heads.No evidence of de-bonding was observed during the cyclic loading;(iii) The stress distribution of the bond length for pre-stressed cables was highly non-uniform.High stress concentrations were observed at both the fixed end and the free end of the bond length both before and immediately after the state of equilibrium is exceeded.The results obtained can be used to evaluate the overall performance of pre-stressed rock anchors subject to seismic loading and their potential as rockfall prevention and stabilization measures.
文摘This study aimed to examine the clinical efficacy of minimally invasive percutaneous catheter drainage(PCD) versus open laparotomy with temporary closure in the treatment of abdominal compartment syndrome(ACS) in patients with early-stage severe acute pancreatitis(SAP). Clinical data of 212 patients who underwent PCD and 61 patients who were given open laparotomy with temporary closure in our hospital over the last 10-year period were retrospectively analyzed, and outcomes were compared, including total and post-decompression intensive care unit(ICU) and hospital stays, physiological data, organ dysfunction, complications, and mortality. The results showed that the organ dysfunction scores were similar between the PCD and open laparotomy groups 72 h after decompression. In the PCD group, 134 of 212(63.2%) patients required postoperative ICU support versus 60 of 61(98.4%) in the open laparotomy group(P〈0.001). Additionally, 87(41.0%) PCD patients experienced complications as compared to 49 of 61(80.3%) in the open laparotomy group(P〈0.001). There were 40(18.9%) and 32(52.5%) deaths, respectively, in the PCD and open laparotomy groups(P〈0.001). In conclusion, minimally invasive PCD is superior to open laparotomy with temporary closure, with fewer complications and deaths occurring in PCD group.
文摘We describe an observational study of clinical, virologic and drug resistance profiles in HIV-positive antiretroviral adherent subjects with stable low level viremia (LLV) 50 - 1000 copies/mL for more than 12 months. Subjects were followed from time of first detectable viral load (VL). In total, 102 episodes of LLV were detected among 80 individuals. The median (mean, range) HIV copy number at genotyping was 250 (486, - 3900) copies/mL after 14 (17.9, 0 - 58) months of LLV. Few patients maintained LLV for the entire 9 years period of observation, with half (52%) experiencing viremic progression following a stable period of LLV either spontaneously or after treatment interruption or failed regimen intensification. In the setting of prolonged periods of sustained LLV, mean duration 22 (range 8 - 106) months, drug resistance (DR) was almost universal. Resistance to ≥1 on-treatment drugs was defined in 97% of specimens and DR to all drugs in the treatment regimen in over half of all patients. Evolution of DR mutations during the period of LLV was observed in 20/28 (71%) subjects with specimens available for follow-up testing. This evolution was associated with viremic progression to levels >1000 copies/mL (p = 0.03). Our data suggest that DR present in patients with LLV is likely to impact long term clinical outcomes, highlighting the importance of optimizing techniques to detect the presence of drug resistant HIV in the setting of LLV and the need for larger prospective studies to assess the emergence of DR in the setting of sustained LLV and the impact of this DR on treatment outcomes.
文摘Visiting the sauna regularly could reduce the risk of dementia,a new study has found.Scientists at the University of East Finland followed more than 2,000middle-aged men for 20 years to find out what factors influenced how many developed cognitive^1 problems in later life.
文摘Acupuncture at a single point is a spe-cial feature in the treatment of acute symp-toms for its simplicity and effectiveness.Theauthor experienced many cases of acuteepigastric pain treated with acupuncture at asingle acupoint with satisfactory results.Pain in the elderly is most often of
文摘The development of tropical karst in Guilin could be dated back to middle Triassic, i.e. up to 240 million years, and the incipient karst landform was formed from the middle Triassic to the early Jurassic, a period with intensive karstification. Later, the karst in the area has experienced three major periods, that is, the weak period from the middle Jurassic to the late Cretaceous; the intensive period in the Tertiary which was significant to the formation of the old Li River; and the third period lasts the Quaternary period which has completed the typical tropical karst landform. Some ideas about the effect of paleo lake water to the formation of the tropical karst and the ages of caves on different levels in Guilin have been put forward.
文摘Cotton has been identified as a crop with promising potential in Namibia.As such,cotton variety evaluation trials have been conducted for yield,fiber qualities,resistance to diseases and pests。