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Experimental Study on the Distribution of Velocity and Pressure near a Submarine Pipeline 被引量:2
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作者 HAN Yan SHI Bing REN Xingyue JING Xiaodong 《Journal of Ocean University of China》 SCIE CAS 2009年第4期404-408,共5页
As a transport means of oil and gas the submarine pipeline has many merits, such as continuous delivery, large conveying capacity, convenient management, etc. A tube was chosen in our study to simulate the submarine p... As a transport means of oil and gas the submarine pipeline has many merits, such as continuous delivery, large conveying capacity, convenient management, etc. A tube was chosen in our study to simulate the submarine pipeline in the experiments. A high accuracy instrument ADV and high precision point-type pressure sensors were used to measure the parameters of the flow field, including the pressure distribution, velocities at seven cross sections near the submarine pipeline with five different clearance ratios, and twelve dynamic pressure values around the pipeline. The pressure distributions and velocity changes around the pipe under dif- ferent flow velocities and clearance ratios were analyzed. These results might be useful for further study of submarine pipeline ero- sion and protection. 展开更多
关键词 submarine pipeline velocity field pressure distribution experiment
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Experimental Study of Confining Pressure Initiated by Tectonic Force 被引量:1
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作者 LuGuxian MaRui +2 位作者 LiuRuixun WangFangzheng GuoChusun 《Journal of China University of Geosciences》 SCIE CSCD 2004年第2期162-166,共5页
An experimental study of the confining pressure, i.e. additional hydrostatic pressure initiated by the tectonic force is presented. The experimental progress is that the σ 1 is gradually increasing from 0 in a l... An experimental study of the confining pressure, i.e. additional hydrostatic pressure initiated by the tectonic force is presented. The experimental progress is that the σ 1 is gradually increasing from 0 in a limiting movement ( ε 1=0) in the σ 1 direction and the speed rate of the accelerating load is 0.4 MPa·s -1 in the lateral and level directions. When σ 2= σ 3<200 MPa, Δ σ l is nearly lacking, Δ σ l is increasing at a high speed only when the horizontal force reaches 250-380 MPa, and Δ σ l almost ceases to increase at the level force of 380 MPa. It is calculated that the tectonic force can produce the confining pressure which is gradually increasing with σ 2= σ 3 before it reaches 380 MPa in an experiment. It is supposed that the horizontal force is almost all transformed into the confining pressure with the increase of the creep deformation of rocks. 展开更多
关键词 tectonic force confining pressure additional hydrostatic pressure experiment.
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An Experimental Study on Atmospheric Pressure Glow Discharge in Different Gases 被引量:2
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作者 刘鹏 詹如娟 +2 位作者 温晓辉 朱晓东 李定 《Plasma Science and Technology》 SCIE EI CAS CSCD 2002年第3期1323-1328,共6页
Usually, the electrical breakdown of dielectric barrier discharge (DBD) at atmo-spheric pressure leads to a filamentary non-homogeneous discharge. However, it is also possible to obtain a diffuse DBD in homogeneous fo... Usually, the electrical breakdown of dielectric barrier discharge (DBD) at atmo-spheric pressure leads to a filamentary non-homogeneous discharge. However, it is also possible to obtain a diffuse DBD in homogeneous form, called atmospheric pressure glow discharge (APGD). We obtained a uniform APGD in helium and in the mixture of argon with alcohol, and studied the electrical characteristics of helium APGD. It is found that the relationship between discharge current and source frequency is different depending on the difference in gas gap when the applied voltage is kept constant. The discharge current shows an increasing trend with the increased frequency when gas gap is 0.8 cm, but the discharge current tends to decrease with the increased frequency when the gas gap increases. The discharge current always increases with the increased applied voltage when the source frequency is kept constant. We also observed a glow-like discharge in nitrogen at atmospheric pressure. 展开更多
关键词 APGD An experimental Study on Atmospheric pressure Glow Discharge in Different Gases In
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Experimental Analysis on the Variable Polarity Plasma Arc Pressure 被引量:1
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作者 JIANG Yi XU Binshi +2 位作者 LUE Yaohui LIU Cunlong LIU Ming 《Chinese Journal of Mechanical Engineering》 SCIE EI CAS CSCD 2011年第4期607-611,共5页
Arc pressure is one of the key factors for variable polarity plasma arc(VPPA) and welding pool formation. In this paper, VPPA pressure is measured by pressure transducer and U-tube barometer methods, and advantages ... Arc pressure is one of the key factors for variable polarity plasma arc(VPPA) and welding pool formation. In this paper, VPPA pressure is measured by pressure transducer and U-tube barometer methods, and advantages and disadvantages of the two methods are compared. The effects of welding parameters, including with straight polarity(SP) current, reverse polarity(RP) current, time ratio of SP to RP, plasma gas flow rate, on VPPA pressure are investigated by using an orthogonal design. The experimental results indicate that the influencing degree of the welding parameters are in the order of plasma gas flow rate, SP current, time ratio of SP to RP, RP current. These results are important to researches of VPPA welding process and its mechanism. The physics behavior of VPPA is taken into account when the above influence mechanisms are analyzed. Firstly, according to the mechanism of the cooling compression to the arc, the compression to VPPA is enhanced with the increase of plasma gas flow, so the VPPA pressure would increase obviously. Secondly, although the temperature of VPPA is as a function of the welding current, the radius of VPPA is also enhanced. So the effects of SP current on VPPA pressure are inferior to the effects of plasma gas flow. Thirdly, VPPA pressure increases as a function of time ratio of SP to RP because the frequency of welding current influences the arc pressure to the some degree; Finally, the RP intervals are farther less than the SP intervals, so the influence to the pressure is minimal. 展开更多
关键词 variable polarity plasma arc arc pressure orthogonal experiment
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Experimental Study of Pore Water Pressure and Bed Profile Change Under Regular Breaking Waves 被引量:1
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作者 程永舟 蒋昌波 +2 位作者 赵利平 潘昀 李青峰 《China Ocean Engineering》 SCIE EI 2012年第3期457-468,共12页
There lies a close relationship between the seabed destruction and the distribution of pore water pressure under the action of breaking wave. The experiments were carried out in a wave flume with a 1:30 sloping sandy... There lies a close relationship between the seabed destruction and the distribution of pore water pressure under the action of breaking wave. The experiments were carried out in a wave flume with a 1:30 sloping sandy seabed to study regular breaking wave induced pore water pressure. A wide range of measurements from the regular wave runs were reported, including time series of wave heights, pore pressures. The video records were analysed to measure the time development of the seabed form and the characteristics of the orbital motion of the sand in the wave breaking region. The pore water pressure in the breaker zone showed the time variation depending on the wave phases including wave breaking and bore propagation. The time-averaged pore water pressure was higher near the seabed surface. The peak values of pore water pressure increase significantly at the breaking point. The direction of pore water pressure difference forces in the breaker zone is of fundamental importance for a correct description of the sediment dynamics. The upwards- directed pressure differences may increase sand transport by reducing the effective weight of the sediment, thereby increasing the bed form evolution. The seabed configuration changed greatly at the wave breaking zone and a sand bar was generated remarkably. The amplitude of the pore water pressure changed with the seabed surface. The results are to improve the understanding of sand transport mechanisms and seabed responses due to breaking regular waves over a sloping sandy bed. 展开更多
关键词 breaking wave pore water pressure sloping sandy seabed flume experiment
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Experimental study of a simple pressure loss coefficient model for multi-hole orifice 被引量:1
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作者 赵天怡 张吉礼 《Journal of Harbin Institute of Technology(New Series)》 EI CAS 2008年第3期399-403,共5页
A throttling experiment for the multi-hole orifice (MO) using water was conducted based on the conclusion of key parameters affecting the MO throttling performance. Testing MOs and standard orifice plates ( SO ) w... A throttling experiment for the multi-hole orifice (MO) using water was conducted based on the conclusion of key parameters affecting the MO throttling performance. Testing MOs and standard orifice plates ( SO ) were designed for the throttling experiment to compare the throttling effect using the equivalent diameter ratio (RED) and diameter ratio (RD ) as key parameters, respectively. Meanwhile, effective metrical conditions were provided for experimental accuracy. The throttling model form was determined according to the theoretical throttling model of SO. Then the unknown parameters involved were identified by experimental data. A good concordance between the modeling computation and experimental results shows a validation of the MO throtting model. 展开更多
关键词 experiment modeling multi-hole orifice pressure loss coefficient
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An Experimental Study on the Pressure Distribution in Horizontal Gas Wells 被引量:1
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作者 Jinbo Liu Ziheng Jiang +4 位作者 Xuezhang Feng Ruiquan Liao Dianfang Feng Xingkai Zhang Hasimu Aikeremu 《Fluid Dynamics & Materials Processing》 EI 2020年第6期176-191,共16页
Laboratory experiments have been carried out to study the fluid flow in the wellbore of a horizontal gas well during the production process.The related pressure distribution has been determined considering different c... Laboratory experiments have been carried out to study the fluid flow in the wellbore of a horizontal gas well during the production process.The related pressure distribution has been determined considering different cases(different inflow media,different perforation opening methods and different liquid holdup).It has been found that the larger the fluid flow rate,the greater the pressure changes in the wellbore under the same hole opening mode.The uniformity of the perforation opening method was also an important factor affecting the magnitude of the wellbore pressure change.The liquid holdup also affected the pressure distribution,especially when the gas volumetric flow rate exceeded 200 m3/h.Comparison of the outcomes of the present experimental study with the predictions of a theoretical model available in the literature has provided a relative error smaller than 20%. 展开更多
关键词 Horizontal gas well laboratory experiment pressure distribution
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Experimental study on the pressure control of soil chamber in shield tunneling 被引量:1
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作者 Qiang ZHANG Shou-Ju LI Li-Juan CAO 《Journal of Coal Science & Engineering(China)》 2013年第3期414-420,共7页
A mathematical model of the soil pressure system in shield tunneling was proposed to optimize soil pressure control in the soil chamber, based on the constitutive relationship between strain and stress. The desired pr... A mathematical model of the soil pressure system in shield tunneling was proposed to optimize soil pressure control in the soil chamber, based on the constitutive relationship between strain and stress. The desired pressure is determined by using the finite element method. A linear quadratic constant state tracking problem was considered over an infinite time interval. The optimal control law was derived by differentiating the Hamilton function with respect to system input. In order to verify the effectiveness of the proposed mathematical model and optimal control law, an experimental study on the pressure control of the soil chamber in shield tunneling was conducted in a laboratory. The experiment results show that soil pressure in the soil chamber in shield tunneling can be accurately controlled. 展开更多
关键词 optimal control soil pressure shield tunneling mathematical model experimental investigation
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Experimental Verification and Research for the Distortion in the Integrated Frequency Responses of the High-Pressure Sealed Cabin and Magnetic Field Sensor 被引量:4
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作者 邓明 魏文博 +3 位作者 金胜 叶高峰 张启升 景建恩 《Journal of China University of Geosciences》 SCIE CSCD 2007年第4期310-319,共10页
Although magnetotelluric sounding method applied to the land is advanced, there are many difficulties when it is applied to marine environment, one of which is how to lay magnetic field sensors down to the seafloor to... Although magnetotelluric sounding method applied to the land is advanced, there are many difficulties when it is applied to marine environment, one of which is how to lay magnetic field sensors down to the seafloor to complete measurements. To protect the magnetic field sensors from intense erosion and high pressure, suitable high-pressure sealed cabins must be designed to load them. For the consideration of magnetic measurement and marine operation, the sealed pressure cabin should be nonmagnetic and transportable. Among all optional materials, LC4 super.hard aluminum alloy has the highest performance of price/quality ratio to make the sealed pressure cabin. However, it does not mean that the high-pressure sealed cabin made using LC4 will be perfect in performance. In fact, because of its weak magnetism, the pressure cabin made using LC4 has distorting effect on frequency responses of the magnetic field sensors sealed in it. This distorting effect does not affect the use of the magnetic field sensor, but if we want to eliminate its effect, we should study it by experimental measurements. In our experiment tests, frequency sweep magnetic field as excitation signal was used, and then responses of the magnetic field sensor before and after being loaded into the high-pressure sealed cabin were measured. Finally, normalized abnormal curves for the frequency responses were obtained, through which we could show how the high-pressure sealed cabin produces effects on the responses of the magnetic field sensor. Experimental results suggest that the response distortion induced by the sealed pressure cabin appears on mid- and high-frequency areas. Using experimental results as standardization data, the frequency responses collected from seafloor magnetotelluric measurements can be corrected to restore real information about the seafloor field source. 展开更多
关键词 marine magnetotellurics magnetic field sensor high-pressure sealed cabin frequency response experimental test
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Experimental Investigation of Unsteady Pressure on an Axial Compressor Rotor Blade Surface
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作者 Qingwei Wang Bo Liu +2 位作者 Xiaorong Xiang Xiangfeng Bo Weimin Hou 《Energy and Power Engineering》 2010年第2期131-136,共6页
The inherent unsteady pressure fluctuations on the rotating blade suction surface of an axial compressor were experimentally measured by directly mounting five high response miniature pressure transducers into the rot... The inherent unsteady pressure fluctuations on the rotating blade suction surface of an axial compressor were experimentally measured by directly mounting five high response miniature pressure transducers into the rotor blade along a streamline at 50% span respectively. The results show that the unsteady pressure fluctuations of rotor blade surface could be measured successfully by this means. The relations about the period, altitude of unsteady pressure with rotating speed, the discipline of pressure fluctuation along the streamwise direction were obtained. 展开更多
关键词 Kulite TRANSDUCER ROTATING BLADE UNSTEADY pressure experimental Measurement
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Experimental Observation of Phase Transition in Sb203 under High Pressure
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作者 耿爱辉 曹立华 +2 位作者 马艳梅 崔启良 万春明 《Chinese Physics Letters》 SCIE CAS CSCD 2016年第9期112-115,共4页
The in situ high-pressure behavior of the semiconductor antimony trioxide (Sb2O3) iS investigated by the Raman spectroscopy techniques and angle-dispersive synchrotron x-ray powder diffractfon in a diamond anvil cel... The in situ high-pressure behavior of the semiconductor antimony trioxide (Sb2O3) iS investigated by the Raman spectroscopy techniques and angle-dispersive synchrotron x-ray powder diffractfon in a diamond anvil cell up to 31.5 and 30.7 GPa, respectively. New peaks observed in the external lattice mode range in the Raman spectra at 13.5 GPa suggest that the structural phase transition occurs. The group mode (140 cm^-1) in Sb2O3 exhibits anomalous pressure dependence; that is, the frequency decreases gradually with the increasing pressure. High pressure synchrotron x-ray diffraction measurements at room temperature reveal that the transition from the orthorhombic structure to high-pressure new phase occurs at about 14.2 GPa, corresponding to the softening of the group optic mode (140cm^-1). 展开更多
关键词 of on AS experimental Observation of Phase Transition in Sb203 under High pressure SB in
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Experimental Investigation of Pressure Drop Hysteresis in a Cocurrent Gas-Liquid Upflow Packed Bed 被引量:1
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作者 徐红彬 毛在砂 《过程工程学报》 CAS CSCD 北大核心 2001年第3期239-242,共4页
Extensive experimental work on hysteresis in a c℃urrent gas-liquid upflow packed bed was carried out with three kinds of packings and the air-water system. However, only when packed with small glass beads ((1.4 mm) w... Extensive experimental work on hysteresis in a c℃urrent gas-liquid upflow packed bed was carried out with three kinds of packings and the air-water system. However, only when packed with small glass beads ((1.4 mm) was the bed pressure drop hysteresis observed. Two more liquids with different liquid properties were employed to further examine the influence of parameters on pressure drop hysteresis. The similarity of pressure drop hysteresis in packed beds was concluded in combination of experimental evidence reported in literature. 展开更多
关键词 气液固填充塔 同向上流固定 压力降滞 试验
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Experimental Investigation on the Pressure Characteristics of Cavity Closure Region
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作者 Yadong Wang Xulong Yuan Yuwen Zhang 《Journal of Marine Science and Application》 2012年第4期462-468,共7页
The most complicated component in cavitating flow and pressure distribution is the flow in the cavity closure line. The cavitating flow and pressure distribution provide critical aspects of flow field details in the r... The most complicated component in cavitating flow and pressure distribution is the flow in the cavity closure line. The cavitating flow and pressure distribution provide critical aspects of flow field details in the region. The integral of pressure results of the hydrodynamic forces, indicate domination in the design of a supercavitating vehicle. An experiment was performed in a water tunnel to investigate the pressure characteristics of the cavity closure region. Ventilation methods were employed to generate artificial cavity, and the ventilation rate was adjusted accordingly to obtain the desired cavity length. An array of pressure transducers was laid down the cavity closure line to capture pressure distribution in this region. The experimental results show that there is a pressure peak in the cavity closure region, and the rise rate of pressure in space tends to be higher in the upwind side when the flow is non-axisymmetric. The transient pressure variations during the cavity formation procedure were also present. The method of measurement in this paper can be referenced by engineers. The result helps to study the flow pattern of cavity closure region, and it can also be used to analyze the formation of supercavitating vehicle hydrodynamics. 展开更多
关键词 HYDRODYNAMICS CAVITY closure region pressure characteristic water tunnel experiment pressure distribution supercavitating vehicle
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The feasibility experimental study of pumping and shunting pump under pressure in water injection station
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作者 Dongbo SHAO Yong WANG Suiwang ZHANG 《International Journal of Technology Management》 2013年第3期34-37,共4页
At present in the process of water injection station operation, starting and stopping the pump caused system pressure fluctuations, and the fluctuations caused many problems about downstream injection wells. In order ... At present in the process of water injection station operation, starting and stopping the pump caused system pressure fluctuations, and the fluctuations caused many problems about downstream injection wells. In order to eliminate the fluctuations and reduce problems, taking start pump, connect pump test under pressure in the water injection station installed the rotor frequency control system Changqing oil field developed. During the experiment, by progressively increasing the pressure pump to verify start pump with pressure feasibility test, the result shows when the pressure in the 0-25MPa pressure start and connect pump can be realized, and forecast the maximum pressure of the current start of the station with pressure pump. Start pump with pressure achieve the elimination of pressure fluctuations, provide the prerequisites about realizeing stable water injection pressure, and ultimately realize oil field water injection station to be automatic water injection laid a foundation. 展开更多
关键词 water injection station wire-wound motor pumping pump under pressure feasibility experiment
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CFD simulation of pressure fluctuation characteristics in the gas-solid fluidized bed:Comparisons with experiments 被引量:3
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作者 Wang Qingcheng Zhang Kai Gu Hongyan 《Petroleum Science》 SCIE CAS CSCD 2011年第2期211-218,共8页
A simple hydrodynamic model based on two-fluid theory, taking into account the effect of discrete particles on both the gas- and solid-phase momentum equations, was used to numerically investigate the pressure fluctua... A simple hydrodynamic model based on two-fluid theory, taking into account the effect of discrete particles on both the gas- and solid-phase momentum equations, was used to numerically investigate the pressure fluctuation characteristics in a gas-solid fluidized bed with the aid of CFX 4.4, a commercial CFD software package, by adding user-defined Fortran subroutines. Numerical simulations together with typical experimental measurements show that pressure fluctuations originate above the distributor when a gas pulse is injected into the fluidized bed. The pressure above the bubble gradually increases due to the presence of a rising bubble. When the bubble passes through the bed surface, the pressure near the bed surface gradually decreases to a lower value. Moreover, the pressure signals in the bubbling fluidized beds show obviously periodic characteristics. The major frequency of pressure fluctuations at the same vertical position is affected slightly by the operating gas velocity, and the amplitude of pressure fluctuations is related to both the operating gas velocity and the vertical height. In this study, the influence of the operating gas velocity on the pressure wave propagation velocity can be ignored, and only two peak frequencies in the power spectrum of the pressure fluctuations are observed which are associated with the bubble formation above the distributor and its eruption at the bed surface. 展开更多
关键词 Gas-solid fluidized bed CFD simulation experimental measurements propagation ofpressure fluctuations pressure wave velocity pressure fluctuation frequency
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In-situ electrochemical study on the eff ects of Fe(Ⅲ)on kinetics of pyrite acidic pressure oxidation
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作者 Yu Zhang Can Cui +7 位作者 Sen Lin Heping Li Lian Yang Yadian Xie Hailiang Hu Lingyun Zhou Huanjiang Wang Chunyan Li 《Acta Geochimica》 EI CAS CSCD 2024年第4期814-825,共12页
Fe(Ⅲ)has been proved to be a more eff ective oxidant than dissolved oxygen at ambient temperature,however,the role of Fe(Ⅲ)in pyrite acidic pressure oxidation was rarely discussed so far.In this paper,in-situ electr... Fe(Ⅲ)has been proved to be a more eff ective oxidant than dissolved oxygen at ambient temperature,however,the role of Fe(Ⅲ)in pyrite acidic pressure oxidation was rarely discussed so far.In this paper,in-situ electrochemical investigation was performed using a flow-through autoclave system in acidic pressure oxidation environment.The results illustrated that increasing Fe(Ⅲ)concentrations led to raising in redox potential of the solution,and decreased passivation of pyrite caused by deposition of elemental sulfur.Reduction of Fe(Ⅲ)at pyrite surface was a fast reaction with low activation energy,it was only slightly promoted by rising temperatures.While,the oxidation rate of pyrite at all investigated Fe(Ⅲ)concentrations increased obviously with rising temperatures,the anodic reaction was the rate-limiting step in the overall reaction.Activation energy of pyrite oxidation decreased from 47.74 to 28.79 kJ/mol when Fe(Ⅲ)concentration was increased from 0.05 to 0.50 g/L,showing that the reaction kinetics were limited by the rate of electrochemical reaction at low Fe(Ⅲ)concentrations,while,it gradually turned to be diffusion control with increasing Fe(Ⅲ)concentrations. 展开更多
关键词 PYRITE pressure oxidation Fe(Ⅲ) In-situ electrochemistry Hydrothermal experiment
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Experiment Research on Fine Regulation of Wheel Cylinder Pressure Using PWM Technology 被引量:2
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作者 佀海 刘昭度 +1 位作者 崔海峰 王斌 《Journal of Beijing Institute of Technology》 EI CAS 2008年第2期153-158,共6页
A test bench of ABS/ASR integrated hydraulic system is developed by using pulse-width modulation (PWM) technology. The effective duty ratio range of ABS outlet valve has been tested in PWM control. With 50 Hz carrie... A test bench of ABS/ASR integrated hydraulic system is developed by using pulse-width modulation (PWM) technology. The effective duty ratio range of ABS outlet valve has been tested in PWM control. With 50 Hz carrier wave frequency, the tests are performed to determine the correspondence between duty ratio and the wheel cylinder pressure variation. The duty ratio range of ABS outlet valve in PWM control is determined and an experimental model of pressure reduction velocity (PRV) of wheel cylinder using PWM control is established. By comparison and test of the experimental model and realization of controlling the duty ratio of ABS outlet valves, the fine regulation of wheel cylinder PRV is realized in the working of ABS/ASR braking regulation, which is important and valuable to the improvement of the ABS/ASR controlling effect. 展开更多
关键词 pulse-width modulation (PWM) pressure reduction velocity (PRV) experimental model
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Protective effects of nerve regeneration factor and brain-derived neurotrophic factor on retinal ganglion cells in a rabbit model of acute hyper-intraocular pressure 被引量:1
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作者 Zhengru Huang Huaijin Guan +1 位作者 Fei Ding Xiaosong Gu 《Neural Regeneration Research》 SCIE CAS CSCD 2010年第6期445-449,共5页
BACKGROUND: Previous studies have shown that nerve regeneration factor (NRF) provides neuroprotective effects. However, the neuroprotective effects on retinal ganglion cells in an animal model of glaucoma remain un... BACKGROUND: Previous studies have shown that nerve regeneration factor (NRF) provides neuroprotective effects. However, the neuroprotective effects on retinal ganglion cells in an animal model of glaucoma remain uncertain. OBJECTIVE: To determine the neuroprotective effects of NRF on retinal ganglion cells in a rabbit model of acute hyper-intraocular pressure and to compare the effects on brain-derived neurotrophic factor (BDNF). DESIGN, TIME AND SETTING: A randomized, controlled, animal experiment was performed at Jiangsu Provincial Key Laboratory of Neural Regeneration from September 2006 to August 2007. MATERIALS: Sterone, a major component of NRF, was provided by the Key Laboratory of Neural Regeneration, Nantong University in China; BDNF was provided by BioDesign Inc., USA. METHODS: A total of 24 healthy rabbits were randomly assigned to NRF, BDNF, and phosphate buffered saline groups, with 8 rabbits per group. The left eyes were considered normal controls, and acute hyper-intraocular pressure was induced in the right eyes via anterior chamber perfusion. The right camera vitrea bulbi was injected with 4.5 μg NRF, 3.75 μg BDNF, or 5 μL 0.1 mol/L phosphate buffered saline, respectively. MAIN OUTCOME MEASURES: Retinal ganglion cells were reverse-labeled using horseradish peroxidase to quantify cell density at 2, 4, and 6 mm from the optic disc edge. RESULTS: NRF increased the number of surviving retinal ganglion cells at the optic disc edge (P 〈 0.01 or P 〈 0.05). The density of surviving retinal ganglion cells decreased with increasing distance from the optic disc. The number of retinal ganglion cells in the BDNF group was similar to the NRF group (P 〉 0.05). At 2, 4, and 6 mm away from the optic disc edge, there was no significant difference in retinal ganglion cell density between NRF and BDNF groups (P〉 0.05). CONCLUSION: NRF provided protection to retinal ganglion cells in a rabbit model of acute hyper-intraocular pressure, Le., NRF enhanced the survival rate of retinal ganglion cells. The neuroprotective effect was similar to BDNF. 展开更多
关键词 nerve regeneration factor brain-derived neurotrophic factor retinal ganglion cells hyper-intraocular pressure NEUROPROTECTION nerve factor neural regeneration
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Experimental models of high-risk bowel anastomosis in rats:A systematic review
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作者 Georgios Ntampakis Manousos-Georgios Pramateftakis +8 位作者 Elissavet Anestiadou Stefanos Bitsianis Orestis Ioannidis Chryssa Bekiari George Koliakos Maria Karakota Anastasia Tsakona Angeliki Cheva Stamatios Angelopoulos Fourth 《World Journal of Experimental Medicine》 2024年第2期114-131,共18页
BACKGROUND Anastomotic leaks remain one of the most dreaded complications in gastrointestinal surgery causing significant morbidity,that negatively affect the patients’quality of life.Experimental studies play an imp... BACKGROUND Anastomotic leaks remain one of the most dreaded complications in gastrointestinal surgery causing significant morbidity,that negatively affect the patients’quality of life.Experimental studies play an important role in understanding the pathophysiological background of anastomotic healing and there are still many fields that require further investigation.Knowledge drawn from these studies can lead to interventions or techniques that can reduce the risk of anastomotic leak in patients with high-risk features.Despite the advances in experimental protocols and techniques,designing a high-quality study is still challenging for the investigators as there is a plethora of different models used.AIM To review current state of the art for experimental protocols in high-risk anastomosis in rats.METHODS This systematic review was performed according to The Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines.To identify eligible studies,a comprehensive literature search was performed in the electronic databases PubMed(MEDLINE)and Scopus,covering the period from conception until 18 October 2023.RESULTS From our search strategy 102 studies were included and were categorized based on the mechanism used to create a high-risk anastomosis.Methods of assessing anastomotic healing were extracted and were individually appraised.CONCLUSION Anastomotic healing studies have evolved over the last decades,but the findings are yet to be translated into human studies.There is a need for high-quality,well-designed studies that will help to the better understanding of the pathophysiology of anastomotic healing and the effects of various interventions. 展开更多
关键词 High-risk anastomosis RATS experimental models BOWEL COLON Anastomotic leak Colon resection Inflammatory bowel disease Intra-abdominal sepsis Bursting pressure
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Cold Flow Experiments and Acoustic Investigation on Pressure Oscillation Induced by Flow Instability
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作者 陈晓龙 何国强 刘佩进 《Defence Technology(防务技术)》 SCIE EI CAS 2010年第2期85-90,共6页
Pressure oscillation in solid rocket motor is believed to be the results of the interaction between the flow instability and the acoustics of combustion chamber.Several reasonable and necessary hypothesizes are given ... Pressure oscillation in solid rocket motor is believed to be the results of the interaction between the flow instability and the acoustics of combustion chamber.Several reasonable and necessary hypothesizes are given to establish an equation to describe this coupling.A cold flow motor called CVS60D(corner vortex shedding 60°)was designed to study the flow-acoustic coupling based on theoretical analysis.Experimental investigations were carried out to determine the acoustics of CVS60D.Corner vortex shedding is generated at the backward facing step which is designed similar to the geometry of the motor with finocyl propellant after the burnout of its fins.A pintle was used to modify the velocity in the duct to change the frequency of vortex shedding.It is found that large amplitude pressure oscillation occurs when the pintle moves to a range of specific position,which indicates that the frequency of vortex shedding is close to one order of acoustic modes of combustion chamber.The amplitude of pressure oscillation changes as the pintle moves. 展开更多
关键词 propulsion system of aviation & aerospace cold flow experiment ACOUSTICS pressure oscillation flow instability
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