Background: The Tiêu equation has a ground roots approach to the process of Quantum Biology and goes deeper through the incorporation of Quantum Mechanics. The process can be measured in plant, animal, and human ...Background: The Tiêu equation has a ground roots approach to the process of Quantum Biology and goes deeper through the incorporation of Quantum Mechanics. The process can be measured in plant, animal, and human usage through a variety of experimental or testing forms. Animal studies were conducted for which, in the first day of the study all the animals consistently gained dramatic weight, even as a toxic substance was introduced as described in the introduction of the paper to harm animal subjects which induced weight loss through toxicity. Tests can be made by incorporating blood report results. Human patients were also observed to show improvement to their health as administration of the substance was introduced to the biological mechanism and plants were initially exposed to the substance to observe results. This is consistent with the Tiêu equation which provides that wave function is created as the introduction of the substance to the biological mechanism which supports Quantum Mechanics. The Tiêu equation demonstrates that Quantum Mechanics moves a particle by temperature producing energy thru the blood-brain barrier for example. Methods: The methods for the Tiêu equation incorporate animal studies to include the substance administered through laboratory standards using Good Laboratory Practices under Title 40 C.F.R. § 158. Human patients were treated with the substance by medical professionals who are experts in their field and have knowledge to the response of patients. Plant applications were acquired for observation and guidance of ongoing experiments of animals’ representative for the biologics mechanism. Results: The animal studies along with patient blood testing results have been an impressive line that has followed the Tiêu equation to consistently show improvement in the introduction of the innovation to biologic mechanisms. The mechanism responds to the substance by producing energy to the mechanism with efficient effect. For plant observations, plant organisms responded, and were seen as showing improvement thru visual observation.展开更多
According to National Science Foundation (NSF) Director A. Bement, ‘Transformative research is... research driven by ideas that stand a reasonable chance of radically changing our understanding of an important exis...According to National Science Foundation (NSF) Director A. Bement, ‘Transformative research is... research driven by ideas that stand a reasonable chance of radically changing our understanding of an important existing scientific concept or leading to the creation of a new paradigm or field of science is also characterized by its challenge to current understanding or its pathway to new frontiers.' Nanotechnology is one of such frontiers. It is the creation of new materials, devices and systems at the molecular level--phenomena associated with atomic and molecular interactions strongly influence macroscopic material properties with significantly improved mechanical, optical, chemical, electrical... properties. Former NSF Director Rita Colwell in 2002 declared, ‘nanoscale technology will have an impact equal to the Industrial Revolution'. The transcendent technologies include nanotechnology, microelectronics, information technology and biotechnology as well as the enabling and supporting mechanical and civil infrastructure systems and materials. These technologies are the primary drivers of the twenty first century and the new economy. Mechanics is an essential eleraent in all of the transcendent technologies. Research opportunities, education and challenges in mechanics, including experimental, numerical and analytical methods in nanomechanics, carbon nano-tubes, bio-inspired materials, fuel cells, as well as improved engineering and design of materials are presented and discussed in this paper.展开更多
Hydraulic structures such as groin, longitudinal dike and seawall are common in water conservancy and water transportation engineering projects at home and abroad, which have long been dominated by solid mass structur...Hydraulic structures such as groin, longitudinal dike and seawall are common in water conservancy and water transportation engineering projects at home and abroad, which have long been dominated by solid mass structural form. With brush and stone as building materials, this kind of structure has an obvious engineering effect. However, it not only requires huge capital investments, but also has negative impacts on the ecological environment. The suspended flexible dam is an innovative engineering measure, and few theoretical and experimental researches of this type dam can be found at present. This paper studies the mechanism and shape characteristics of this dam and obtains the dynamic equilibrium equation of flexible dam, the float buoyancy expression, and the condition for transformation among three forms of the underwater shape of the dam. The results are valuable in engineering application and can be used as the reference for the future work due to the distinctive design philosophy, the small negative effects on environment and the consistency for sustainable development.展开更多
Two rock samples with different structures and materials were deformed under a biaxial loading system, and multi-point strain measurements were performed for each sample. The distribution of strain anomalies during th...Two rock samples with different structures and materials were deformed under a biaxial loading system, and multi-point strain measurements were performed for each sample. The distribution of strain anomalies during the deformation and the instability process were analyzed by using Cv value put forward by WANG Xiao-qing and CHEN Xue-zhong, et al, a parameter to describe the heterogeneous distribution of earthquake precursors, so as to examine the method of Cv value and to explore its physical meaning experimentally. The result shows that the change of Cv value is correlated to the change of deformation characteristics and is an effective parameter to describe the heterogeneity of precursor distribution. Cv value increases firstly and then decreases before the instability, and the instability occurs when Cv value decreases to the level before increasing. This indicates that Cv value may be a useful parameter for earthquake prediction.展开更多
Two kinds of clamping in micro/nano scale experiments are investigated in this paper, one based on electron-beam-induced deposition, and the other on the van der Waals interaction. The clamping strength and mechanism ...Two kinds of clamping in micro/nano scale experiments are investigated in this paper, one based on electron-beam-induced deposition, and the other on the van der Waals interaction. The clamping strength and mechanism are analyzed both theoretically and experimentally. The influence of relative humidity on the micro/nano clamping and the method of electrostatic clamping are discussed. The clamping strength and performance of different clamping methods are compared considering the size and material of the clamped objects, and the application environments.展开更多
The development of personalized healthcare is rapidly growing thanks to the support of low-power electronics,advanced fabrication processes and secured data transmission protocols.Long-acting drug delivery systems abl...The development of personalized healthcare is rapidly growing thanks to the support of low-power electronics,advanced fabrication processes and secured data transmission protocols.Long-acting drug delivery systems able to sustain the release of therapeutics in a controllable manner can provide several advantages in the treatment of chronic diseases.Various systems under development control drug release from an implantable reservoir via concentration driven diffusion through nanofluidic membranes.Given the high drug concentration in the reservoir,an inward osmotic fluid transport occurs across the membrane,which counters the outward diffusion of drugs.The resulting osmotic pressure buildup may be sufficient to cause the failure of implants with associated risks to patients.Confidently assessing the osmotic pressure buildup requires testing in vivo.Here,using metal and polymer AM(additive manufacturing)processes,we designed and developed implantable drug reservoirs with embedded strain sensors to directly measure the osmotic pressure in drug delivery implants in vitro and in vivo.展开更多
In order to analyze the factors influencing sandstone mechanical compaction and its physical property evolution during compaction processes, simulation exper- iments on sandstone mechanical compaction were carried out...In order to analyze the factors influencing sandstone mechanical compaction and its physical property evolution during compaction processes, simulation exper- iments on sandstone mechanical compaction were carried out with a self-designed diagenetic simulation system. The experimental materials were modem sediments from dif- ferent sources, and the experiments were conducted under high temperature and high pressure. Results of the exper- iments show a binary function relation between primary porosity and mean size as well as sorting. With increasing overburden pressure during mechanical compaction, the evolution of porosity and permeability can be divided into rapid compaction at an early stage and slow compaction at a late stage, and the dividing pressure value of the two stages is about 12 MPa and the corresponding depth is about 600 m. In the slow compaction stage, there is a good exponential relationship between porosity and overburden pressure, while a good power function relationship exists between permeability and overburden pressure. There is also a good exponential relationship between porosity and permeability. The influence of particle size on sandstone mechanical compaction is mainly reflected in the slowcompaction stage, and the influence of sorting is mainly reflected in the rapid compaction stage. Abnormally high pressure effectively inhibits sandstone mechanical com- paction, and its control on sandstone mechanical com- paction is stronger than that of particle size and sorting. The influence of burial time on sandstone mechanical compaction is mainly in the slow compaction stage, and the porosity reduction caused by compaction is mainly con- trolled by average particle size.展开更多
Axial structural damping behavior induced by internal friction and viscoelastic properties of polymeric layers may have an inevitable influence on the global analysis of flexible pipes.In order to characterize this ph...Axial structural damping behavior induced by internal friction and viscoelastic properties of polymeric layers may have an inevitable influence on the global analysis of flexible pipes.In order to characterize this phenomenon and axial mechanical responses,a full-scale axial tensile experiment on a complex flexible pipe is conducted at room temperature,in which oscillation forces at different frequencies are applied on the sample.The parameters to be identified are axial strains which are measured by three kinds of instrumentations:linear variable differential transformer,strain gauge and camera united particle-tracking technology.The corresponding plots of axial force versus axial elongation exhibit obvious nonlinear hysteretic relationship.Consequently,the loss factor related to the axial structural damping behavior is found,which increases as the oscillation loading frequency grows.The axial strains from the three measurement systems in the mechanical experiment indicate good agreement,as well as the values of the equivalent axial stiffness.The damping generated by polymeric layers is relatively smaller than that caused by friction forces.Therefore,it can be concluded that friction forces maybe dominate the axial structural damping,especially on the conditions of high frequency.展开更多
In order to improve the comprehensive utilization of solid waste such as iron tailings and waste glass and so on,mechanical property test of cement tailings mortar mixed waste glass and curing mechanism research were ...In order to improve the comprehensive utilization of solid waste such as iron tailings and waste glass and so on,mechanical property test of cement tailings mortar mixed waste glass and curing mechanism research were conducted in the key materials mechanics lab of Liaoning province.The experimental results show that adding waste glass particles can improve the grain size distribution of tailings.The effect is proportional to the content.The compressive strength of tailings mortar has increased significantly.The fineness modulus of tailings mortar mixture adding waste glass powder was gradually reducing with the increase of the dosage of waste glass powder,but the compressive strength of the mixture has gradually enhanced with the increase of the dosage.Microscopic analysis shows that the waste glass particles in the mortar mainly play a role of coarse aggregate and glass powder after grinding fine below a certain size shows strong volcanic activity,which can act hydration with tailings,at the same time glass powder also,plays a role in fine aggregate filling.Therefore,all of glass particles and glass powder can be used as the additive material for improving and optimizing the mechanical property of tailings mortar.展开更多
Underground lifeline engineering (ULE for short) in modern city demands the appreciation of an active fault in buried bedrock . Generally speaking , a large number of urban geological textures of a basement may all be...Underground lifeline engineering (ULE for short) in modern city demands the appreciation of an active fault in buried bedrock . Generally speaking , a large number of urban geological textures of a basement may all be simplified into a dual geological texture model , i. e., the upper part of the basement consists of loose covering layer and the lower part consists of bedrock . The study of an active fault should include three parts of contents , i . e ., to determine the lower time limit of activity of the fault , and the time limit must be recognized by both of designing engineers and geologists ; on the basis of the studies of repetition periods of earthquake occurrence to deter mine whether the fault moves or not during the allowed time of efficacy of buildings and constructions ; for the sake of engineering practice , the active rate of the fault must be given . The fault with different active mechanism has different effects on the ULE . The authors studied the effect of lateral non-uniform overburden site on the ULE by means of the supersonic earthquake modelling . Owing to the lateral non - uniformity of the covering sediments , there occurs an obvious jump of amplitude of the seismic wave propagation near the contact surface between two different sedi ments . In addition , from the modelling experiment curves it may be seen that the different focus mechanisms and different medium characters may also exert an effect in different degrees .展开更多
Amyotrophic lateral sclerosis(ALS) is the most common degenerative disease of the motor neuron system. Over the last years, a growing interest was aimed to discovery new innovative and safer therapeutic approaches i...Amyotrophic lateral sclerosis(ALS) is the most common degenerative disease of the motor neuron system. Over the last years, a growing interest was aimed to discovery new innovative and safer therapeutic approaches in the ALS treatment. In this context, the bioactive compounds of Cannabis sativa have shown antioxidant, anti-inflammatory and neuroprotective effects in preclinical models of central nervous system disease. However, most of the studies proving the ability of cannabinoids in delay disease progression and prolong survival in ALS were performed in animal model, whereas the few clinical trials that investigated cannabinoids-based medicines were focused only on the alleviation of ALS-related symptoms, not on the control of disease progression. The aim of this report was to provide a short but important overview of evidences that are useful to better characterize the efficacy as well as the molecular pathways modulated by cannabinoids.展开更多
Discrete element modeling requires the proper quantification of the behavior of grains at their contacts including the normal force-displacement and tangential force-displacement relationships to be used as input for ...Discrete element modeling requires the proper quantification of the behavior of grains at their contacts including the normal force-displacement and tangential force-displacement relationships to be used as input for contact modeling purposes.This paper reports on recent advances in soil mechanics experimentation which allowed measuring the grain contact behavior of small sand particles quantifying friction and stiffness with sliding tests of a force-controlled or displacement-controlled type.The particular focus of this work is on the micromechanical behavior of quartz type grains of size between about 1 and 5 mm.A description of the developed micromechanical apparatus at City University of Hong Kong is first discussed and its important different capabilities with previously developed apparatus is briefly reviewed.Subsequently,a limited set of new data is reported and discussed along with a review of recently acquired results published in the literature associated with the contact behavior of quartz sand grains.These sliding tests have covered a wider range of normal contact forces from about 0.5 to 8 N,and the results indicated that,for this range of confining forces,there is not any notable change of the inter-particle coefficient of friction.展开更多
The underwater counter-rotation propeller non-cavitation noise has an obvious mod- ulation characteristic which is due to the interaction of flow and blade. A modulation mecha- nism is presented in this paper. A sound...The underwater counter-rotation propeller non-cavitation noise has an obvious mod- ulation characteristic which is due to the interaction of flow and blade. A modulation mecha- nism is presented in this paper. A sound pressure spectrum model is presented to describe its non-cavitation noise with application of generalized acoustic analogy method, the modulation mechanism is expressed with the improvement of sound pressure model. The power spectrum and modulation spectrum are presented by numerical simulation. Theoretical analysis and nu- merical simulation results are verified by the cavitation tunnel experiment. The modulation model of counter-rotation propeller is beneficial to the prediction modulation characteristics and identification of underwater high-speed vehicles.展开更多
The mechanism of percutaneous transluminal renal angioplasty (PTRA) was studied in 18 dogs. The dogs were divided into two groups. Seven dogs were in the early group and eleven were within 1-3 weeks after PTRA. A 4 / ...The mechanism of percutaneous transluminal renal angioplasty (PTRA) was studied in 18 dogs. The dogs were divided into two groups. Seven dogs were in the early group and eleven were within 1-3 weeks after PTRA. A 4 / 0 resorbable chronic catgut was used to Hgate subtotally the renal artery to create fibromuscular dysplasia. PTRA was performed after renal artery stenosis for 6-8 weeks. The changes of ultrastructure of renal artery were studied. A countrary orientation balance hypothesis was proposed to explain the mechanism of PTRA.展开更多
The present work is intended to simulate, in a rotating annulus of stratified liquid, the me-chanical effect of the Xizang (Tibetan) Plateau on the zonal circulation. The main featuresof three flow patterns around the...The present work is intended to simulate, in a rotating annulus of stratified liquid, the me-chanical effect of the Xizang (Tibetan) Plateau on the zonal circulation. The main featuresof three flow patterns around the plateau for different Rossby number R and rotating Eulernumber E are analysed. and a division diagram of the flow pattern in (R, E) plane is given.It has been found that under the condition that similarity criterions R and E of the experimentalfluid are the same as those existing in the atmosphere for monthly mean states in spring, au-tumn and winter months, the experimental results are satisfied for the following weathersystems over the plateau and its vicinities: the low vortex, trough and shear line over thesoutheast part of the plateau, the tilted ridge over the northwest part of the plateau, the troughpatterns over the upstream and dewnstream of the plateau, the vertical circulation structure, thejets on both north and southeast sides of the plateau, and so on. This shows that the展开更多
The mechanical properties of biological soft tissues are inextricably linked to the field of health care,and their mechanical properties can be important indicators for diagnosing and detecting diseases;they can also ...The mechanical properties of biological soft tissues are inextricably linked to the field of health care,and their mechanical properties can be important indicators for diagnosing and detecting diseases;they can also be used to analyze the causes of organ diseases from a pathological point of view and thus guide the deployment of medical solutions.As an effective method to characterize the mechanical properties of materials,mechanical loading experiments have been successfully applied to the mechanical properties of materials,including tension,compression,pure shear,and so on.Under quasi-static loading,when the material is a biological soft tissue material between a solid and an ideal fluid,its viscoelastic properties strongly respond to the force stimulus,and the stress-strain-time in the elastic phase will have obvious disturbance characteristics.Therefore,the existing statistical methods are often difficult to quantitatively describe the mechanical properties of materials.Therefore,this study proposes an Interval Capture Point based on the principle of integration.The experimental data based on this method can characterize its nonlinear mechanical properties well,especially when the loading speed is extremely low and the soft materials show strong disturbance characteristics.The proposed method can still accurately characterize the hyperelastic and viscoelastic properties of the mechanical properties of biological soft tissues under quasi-static loading.展开更多
High-speed target three-dimensional[3D]trajectory and velocity measurement methods have important uses in many fields,including explosive debris and rotating specimen trajectory tracking.The conventional approach uses...High-speed target three-dimensional[3D]trajectory and velocity measurement methods have important uses in many fields,including explosive debris and rotating specimen trajectory tracking.The conventional approach uses a binocular system with two high-speed cameras to capture the target’s 3D motion information.Hardware cost for the conventional approach is high,and accurately triggering several high-speed cameras is difficult.Event-based cameras have recently received considerable attention due to advantages in dynamic range,temporal resolution,and power consumption.To address problems of camera synchronization difficulties,data redundancy,and motion blur in high-speed target 3D trajectory measurement,this Letter proposes a 3D trajectory measurement method based on a single-event camera and a four-mirror adaptor.The 3D trajectory and velocity of a particle flight process and a marker on a rotating disc were measured with the proposed method,and the results show that the proposed method can monitor the operational state of high-speed flying and rotating objects at a very low hardware cost.展开更多
Research into the fundamental properties of microcapsules and use of the results to develop a wide variety of products in industries such as printing, fast-moving consumer goods, construction, pharmaceuticals, and agr...Research into the fundamental properties of microcapsules and use of the results to develop a wide variety of products in industries such as printing, fast-moving consumer goods, construction, pharmaceuticals, and agrochemicals is a dynamic and ever-progressing field of study. For microcapsules to be effective in providing protection from harsh environments or delivering large payloads, it is essential to have a good understanding of their properties to enable quality control during formulation, storage, and applications. This review aims to outline the commonly used techniques for determining the physicochemical, struc- tural, and mechanical properties of microcapsules, and highlights the interlinked nature of these three areas with respect to the end-use industrial application. This review provides information on techniques that are well supported in the literature, and also examines microcapsule analytical techniques that will become more prevalent as a result of new technological developments or extensions from other areas of study.展开更多
文摘Background: The Tiêu equation has a ground roots approach to the process of Quantum Biology and goes deeper through the incorporation of Quantum Mechanics. The process can be measured in plant, animal, and human usage through a variety of experimental or testing forms. Animal studies were conducted for which, in the first day of the study all the animals consistently gained dramatic weight, even as a toxic substance was introduced as described in the introduction of the paper to harm animal subjects which induced weight loss through toxicity. Tests can be made by incorporating blood report results. Human patients were also observed to show improvement to their health as administration of the substance was introduced to the biological mechanism and plants were initially exposed to the substance to observe results. This is consistent with the Tiêu equation which provides that wave function is created as the introduction of the substance to the biological mechanism which supports Quantum Mechanics. The Tiêu equation demonstrates that Quantum Mechanics moves a particle by temperature producing energy thru the blood-brain barrier for example. Methods: The methods for the Tiêu equation incorporate animal studies to include the substance administered through laboratory standards using Good Laboratory Practices under Title 40 C.F.R. § 158. Human patients were treated with the substance by medical professionals who are experts in their field and have knowledge to the response of patients. Plant applications were acquired for observation and guidance of ongoing experiments of animals’ representative for the biologics mechanism. Results: The animal studies along with patient blood testing results have been an impressive line that has followed the Tiêu equation to consistently show improvement in the introduction of the innovation to biologic mechanisms. The mechanism responds to the substance by producing energy to the mechanism with efficient effect. For plant observations, plant organisms responded, and were seen as showing improvement thru visual observation.
文摘According to National Science Foundation (NSF) Director A. Bement, ‘Transformative research is... research driven by ideas that stand a reasonable chance of radically changing our understanding of an important existing scientific concept or leading to the creation of a new paradigm or field of science is also characterized by its challenge to current understanding or its pathway to new frontiers.' Nanotechnology is one of such frontiers. It is the creation of new materials, devices and systems at the molecular level--phenomena associated with atomic and molecular interactions strongly influence macroscopic material properties with significantly improved mechanical, optical, chemical, electrical... properties. Former NSF Director Rita Colwell in 2002 declared, ‘nanoscale technology will have an impact equal to the Industrial Revolution'. The transcendent technologies include nanotechnology, microelectronics, information technology and biotechnology as well as the enabling and supporting mechanical and civil infrastructure systems and materials. These technologies are the primary drivers of the twenty first century and the new economy. Mechanics is an essential eleraent in all of the transcendent technologies. Research opportunities, education and challenges in mechanics, including experimental, numerical and analytical methods in nanomechanics, carbon nano-tubes, bio-inspired materials, fuel cells, as well as improved engineering and design of materials are presented and discussed in this paper.
文摘Hydraulic structures such as groin, longitudinal dike and seawall are common in water conservancy and water transportation engineering projects at home and abroad, which have long been dominated by solid mass structural form. With brush and stone as building materials, this kind of structure has an obvious engineering effect. However, it not only requires huge capital investments, but also has negative impacts on the ecological environment. The suspended flexible dam is an innovative engineering measure, and few theoretical and experimental researches of this type dam can be found at present. This paper studies the mechanism and shape characteristics of this dam and obtains the dynamic equilibrium equation of flexible dam, the float buoyancy expression, and the condition for transformation among three forms of the underwater shape of the dam. The results are valuable in engineering application and can be used as the reference for the future work due to the distinctive design philosophy, the small negative effects on environment and the consistency for sustainable development.
基金Chinese Joint Earthquake Sciences Foundation (9507435).
文摘Two rock samples with different structures and materials were deformed under a biaxial loading system, and multi-point strain measurements were performed for each sample. The distribution of strain anomalies during the deformation and the instability process were analyzed by using Cv value put forward by WANG Xiao-qing and CHEN Xue-zhong, et al, a parameter to describe the heterogeneous distribution of earthquake precursors, so as to examine the method of Cv value and to explore its physical meaning experimentally. The result shows that the change of Cv value is correlated to the change of deformation characteristics and is an effective parameter to describe the heterogeneity of precursor distribution. Cv value increases firstly and then decreases before the instability, and the instability occurs when Cv value decreases to the level before increasing. This indicates that Cv value may be a useful parameter for earthquake prediction.
基金supported by the NSFC (Nos10972113,10572071 and 10732080)the National Basic Research Program of China (Nos2007CB936803 and 2010CB631005)the SRFDP (No20070003053) and the Central Laboratory of Strength and Vibration of Tsinghua University
文摘Two kinds of clamping in micro/nano scale experiments are investigated in this paper, one based on electron-beam-induced deposition, and the other on the van der Waals interaction. The clamping strength and mechanism are analyzed both theoretically and experimentally. The influence of relative humidity on the micro/nano clamping and the method of electrostatic clamping are discussed. The clamping strength and performance of different clamping methods are compared considering the size and material of the clamped objects, and the application environments.
文摘The development of personalized healthcare is rapidly growing thanks to the support of low-power electronics,advanced fabrication processes and secured data transmission protocols.Long-acting drug delivery systems able to sustain the release of therapeutics in a controllable manner can provide several advantages in the treatment of chronic diseases.Various systems under development control drug release from an implantable reservoir via concentration driven diffusion through nanofluidic membranes.Given the high drug concentration in the reservoir,an inward osmotic fluid transport occurs across the membrane,which counters the outward diffusion of drugs.The resulting osmotic pressure buildup may be sufficient to cause the failure of implants with associated risks to patients.Confidently assessing the osmotic pressure buildup requires testing in vivo.Here,using metal and polymer AM(additive manufacturing)processes,we designed and developed implantable drug reservoirs with embedded strain sensors to directly measure the osmotic pressure in drug delivery implants in vitro and in vivo.
基金co-funded by the National Natural Science Foundation of China (Grant No.U1262203)the National Science and Technology Special Grant (Grant No.2011ZX05009003)+1 种基金the Fundamental Research Funds for the Central Universities (Grant No.14CX06013A)the Chinese Scholarship Council (No.201406450019)
文摘In order to analyze the factors influencing sandstone mechanical compaction and its physical property evolution during compaction processes, simulation exper- iments on sandstone mechanical compaction were carried out with a self-designed diagenetic simulation system. The experimental materials were modem sediments from dif- ferent sources, and the experiments were conducted under high temperature and high pressure. Results of the exper- iments show a binary function relation between primary porosity and mean size as well as sorting. With increasing overburden pressure during mechanical compaction, the evolution of porosity and permeability can be divided into rapid compaction at an early stage and slow compaction at a late stage, and the dividing pressure value of the two stages is about 12 MPa and the corresponding depth is about 600 m. In the slow compaction stage, there is a good exponential relationship between porosity and overburden pressure, while a good power function relationship exists between permeability and overburden pressure. There is also a good exponential relationship between porosity and permeability. The influence of particle size on sandstone mechanical compaction is mainly reflected in the slowcompaction stage, and the influence of sorting is mainly reflected in the rapid compaction stage. Abnormally high pressure effectively inhibits sandstone mechanical com- paction, and its control on sandstone mechanical com- paction is stronger than that of particle size and sorting. The influence of burial time on sandstone mechanical compaction is mainly in the slow compaction stage, and the porosity reduction caused by compaction is mainly con- trolled by average particle size.
基金the support from the National Natural Science Foundation of China(Youth Program)(Grant No.51809276)the National Key Research and Development Plan of China(Grant No.2018YFC0310504)CNPq-National Council of Scientific and Technological Development(Grant No.302380/2013-2)。
文摘Axial structural damping behavior induced by internal friction and viscoelastic properties of polymeric layers may have an inevitable influence on the global analysis of flexible pipes.In order to characterize this phenomenon and axial mechanical responses,a full-scale axial tensile experiment on a complex flexible pipe is conducted at room temperature,in which oscillation forces at different frequencies are applied on the sample.The parameters to be identified are axial strains which are measured by three kinds of instrumentations:linear variable differential transformer,strain gauge and camera united particle-tracking technology.The corresponding plots of axial force versus axial elongation exhibit obvious nonlinear hysteretic relationship.Consequently,the loss factor related to the axial structural damping behavior is found,which increases as the oscillation loading frequency grows.The axial strains from the three measurement systems in the mechanical experiment indicate good agreement,as well as the values of the equivalent axial stiffness.The damping generated by polymeric layers is relatively smaller than that caused by friction forces.Therefore,it can be concluded that friction forces maybe dominate the axial structural damping,especially on the conditions of high frequency.
基金Found by the National Natural Science Foundation of China(Nos.51279109 and 51474050)the Liaoning Education Department Funds(No.201364088)
文摘In order to improve the comprehensive utilization of solid waste such as iron tailings and waste glass and so on,mechanical property test of cement tailings mortar mixed waste glass and curing mechanism research were conducted in the key materials mechanics lab of Liaoning province.The experimental results show that adding waste glass particles can improve the grain size distribution of tailings.The effect is proportional to the content.The compressive strength of tailings mortar has increased significantly.The fineness modulus of tailings mortar mixture adding waste glass powder was gradually reducing with the increase of the dosage of waste glass powder,but the compressive strength of the mixture has gradually enhanced with the increase of the dosage.Microscopic analysis shows that the waste glass particles in the mortar mainly play a role of coarse aggregate and glass powder after grinding fine below a certain size shows strong volcanic activity,which can act hydration with tailings,at the same time glass powder also,plays a role in fine aggregate filling.Therefore,all of glass particles and glass powder can be used as the additive material for improving and optimizing the mechanical property of tailings mortar.
基金The paper is one Part of a project supported by National Education Commitce Funds for Doctoral Faculty
文摘Underground lifeline engineering (ULE for short) in modern city demands the appreciation of an active fault in buried bedrock . Generally speaking , a large number of urban geological textures of a basement may all be simplified into a dual geological texture model , i. e., the upper part of the basement consists of loose covering layer and the lower part consists of bedrock . The study of an active fault should include three parts of contents , i . e ., to determine the lower time limit of activity of the fault , and the time limit must be recognized by both of designing engineers and geologists ; on the basis of the studies of repetition periods of earthquake occurrence to deter mine whether the fault moves or not during the allowed time of efficacy of buildings and constructions ; for the sake of engineering practice , the active rate of the fault must be given . The fault with different active mechanism has different effects on the ULE . The authors studied the effect of lateral non-uniform overburden site on the ULE by means of the supersonic earthquake modelling . Owing to the lateral non - uniformity of the covering sediments , there occurs an obvious jump of amplitude of the seismic wave propagation near the contact surface between two different sedi ments . In addition , from the modelling experiment curves it may be seen that the different focus mechanisms and different medium characters may also exert an effect in different degrees .
文摘Amyotrophic lateral sclerosis(ALS) is the most common degenerative disease of the motor neuron system. Over the last years, a growing interest was aimed to discovery new innovative and safer therapeutic approaches in the ALS treatment. In this context, the bioactive compounds of Cannabis sativa have shown antioxidant, anti-inflammatory and neuroprotective effects in preclinical models of central nervous system disease. However, most of the studies proving the ability of cannabinoids in delay disease progression and prolong survival in ALS were performed in animal model, whereas the few clinical trials that investigated cannabinoids-based medicines were focused only on the alleviation of ALS-related symptoms, not on the control of disease progression. The aim of this report was to provide a short but important overview of evidences that are useful to better characterize the efficacy as well as the molecular pathways modulated by cannabinoids.
基金The work described in this paper was supported by a grant from the Research Grants Council of the Hong Kong Special Administrative Region,China(Project No.CityU 8779012).
文摘Discrete element modeling requires the proper quantification of the behavior of grains at their contacts including the normal force-displacement and tangential force-displacement relationships to be used as input for contact modeling purposes.This paper reports on recent advances in soil mechanics experimentation which allowed measuring the grain contact behavior of small sand particles quantifying friction and stiffness with sliding tests of a force-controlled or displacement-controlled type.The particular focus of this work is on the micromechanical behavior of quartz type grains of size between about 1 and 5 mm.A description of the developed micromechanical apparatus at City University of Hong Kong is first discussed and its important different capabilities with previously developed apparatus is briefly reviewed.Subsequently,a limited set of new data is reported and discussed along with a review of recently acquired results published in the literature associated with the contact behavior of quartz sand grains.These sliding tests have covered a wider range of normal contact forces from about 0.5 to 8 N,and the results indicated that,for this range of confining forces,there is not any notable change of the inter-particle coefficient of friction.
基金supported by the National Natural Science Foundation of China(11704345)the Key Laboratory of Science and Technology for National Defence Foundation(9140C290304140C29133)
文摘The underwater counter-rotation propeller non-cavitation noise has an obvious mod- ulation characteristic which is due to the interaction of flow and blade. A modulation mecha- nism is presented in this paper. A sound pressure spectrum model is presented to describe its non-cavitation noise with application of generalized acoustic analogy method, the modulation mechanism is expressed with the improvement of sound pressure model. The power spectrum and modulation spectrum are presented by numerical simulation. Theoretical analysis and nu- merical simulation results are verified by the cavitation tunnel experiment. The modulation model of counter-rotation propeller is beneficial to the prediction modulation characteristics and identification of underwater high-speed vehicles.
文摘The mechanism of percutaneous transluminal renal angioplasty (PTRA) was studied in 18 dogs. The dogs were divided into two groups. Seven dogs were in the early group and eleven were within 1-3 weeks after PTRA. A 4 / 0 resorbable chronic catgut was used to Hgate subtotally the renal artery to create fibromuscular dysplasia. PTRA was performed after renal artery stenosis for 6-8 weeks. The changes of ultrastructure of renal artery were studied. A countrary orientation balance hypothesis was proposed to explain the mechanism of PTRA.
文摘The present work is intended to simulate, in a rotating annulus of stratified liquid, the me-chanical effect of the Xizang (Tibetan) Plateau on the zonal circulation. The main featuresof three flow patterns around the plateau for different Rossby number R and rotating Eulernumber E are analysed. and a division diagram of the flow pattern in (R, E) plane is given.It has been found that under the condition that similarity criterions R and E of the experimentalfluid are the same as those existing in the atmosphere for monthly mean states in spring, au-tumn and winter months, the experimental results are satisfied for the following weathersystems over the plateau and its vicinities: the low vortex, trough and shear line over thesoutheast part of the plateau, the tilted ridge over the northwest part of the plateau, the troughpatterns over the upstream and dewnstream of the plateau, the vertical circulation structure, thejets on both north and southeast sides of the plateau, and so on. This shows that the
基金supported by the National Natural Science Foundation of China[U2241273,12172034,U20A20390,11827803]Beijing Municipal Natural Science Foundation[7212205]the 111 project[B13003]]and the Fundamental Research Funds for the Central Universities.
文摘The mechanical properties of biological soft tissues are inextricably linked to the field of health care,and their mechanical properties can be important indicators for diagnosing and detecting diseases;they can also be used to analyze the causes of organ diseases from a pathological point of view and thus guide the deployment of medical solutions.As an effective method to characterize the mechanical properties of materials,mechanical loading experiments have been successfully applied to the mechanical properties of materials,including tension,compression,pure shear,and so on.Under quasi-static loading,when the material is a biological soft tissue material between a solid and an ideal fluid,its viscoelastic properties strongly respond to the force stimulus,and the stress-strain-time in the elastic phase will have obvious disturbance characteristics.Therefore,the existing statistical methods are often difficult to quantitatively describe the mechanical properties of materials.Therefore,this study proposes an Interval Capture Point based on the principle of integration.The experimental data based on this method can characterize its nonlinear mechanical properties well,especially when the loading speed is extremely low and the soft materials show strong disturbance characteristics.The proposed method can still accurately characterize the hyperelastic and viscoelastic properties of the mechanical properties of biological soft tissues under quasi-static loading.
基金supported by the National Natural Science Foundation of China(Nos.12102423,11872354,and11627803)the Fundamental Research Funds for the Central Universities(No.WK2090000033)the Strategic Priority Research Program of the Chinese Academy of Sciences(No.XDB22040502)。
文摘High-speed target three-dimensional[3D]trajectory and velocity measurement methods have important uses in many fields,including explosive debris and rotating specimen trajectory tracking.The conventional approach uses a binocular system with two high-speed cameras to capture the target’s 3D motion information.Hardware cost for the conventional approach is high,and accurately triggering several high-speed cameras is difficult.Event-based cameras have recently received considerable attention due to advantages in dynamic range,temporal resolution,and power consumption.To address problems of camera synchronization difficulties,data redundancy,and motion blur in high-speed target 3D trajectory measurement,this Letter proposes a 3D trajectory measurement method based on a single-event camera and a four-mirror adaptor.The 3D trajectory and velocity of a particle flight process and a marker on a rotating disc were measured with the proposed method,and the results show that the proposed method can monitor the operational state of high-speed flying and rotating objects at a very low hardware cost.
文摘Research into the fundamental properties of microcapsules and use of the results to develop a wide variety of products in industries such as printing, fast-moving consumer goods, construction, pharmaceuticals, and agrochemicals is a dynamic and ever-progressing field of study. For microcapsules to be effective in providing protection from harsh environments or delivering large payloads, it is essential to have a good understanding of their properties to enable quality control during formulation, storage, and applications. This review aims to outline the commonly used techniques for determining the physicochemical, struc- tural, and mechanical properties of microcapsules, and highlights the interlinked nature of these three areas with respect to the end-use industrial application. This review provides information on techniques that are well supported in the literature, and also examines microcapsule analytical techniques that will become more prevalent as a result of new technological developments or extensions from other areas of study.