In view of the key role of undergraduate experimental teaching reform in cultivating high-quality talents with both innovative spirit and practical ability,this paper deeply discusses multi-dimensional reform strategi...In view of the key role of undergraduate experimental teaching reform in cultivating high-quality talents with both innovative spirit and practical ability,this paper deeply discusses multi-dimensional reform strategies.Specifically,the teaching mode of"double teachers for every student"is innovatively introduced,and scientific research projects are deeply integrated into undergraduate experimental teaching,aiming at realizing the modern development of teaching content and the diversified expansion of teaching methods.By designing and applying the undergraduate experimental teaching platform for intelligent limb rehabilitation training based on the concept of"medical-engineering interdisciplinary crossing",it not only builds a bridge for students to contact cutting-edge scientific research and strengthen practical skills,but also provides valuable ideas and practical models for the innovation of undergraduate experimental teaching.In the future,with the continuous optimization and upgrading of platform functions,it is expected to provide students with a richer and richer learning experience and comprehensively promote students'overall quality.展开更多
This study closely follows the spirit of the first class undergraduate education action plan(2021-2025)of University of Shanghai for Science and Technology,combines with the national first-class undergraduate professi...This study closely follows the spirit of the first class undergraduate education action plan(2021-2025)of University of Shanghai for Science and Technology,combines with the national first-class undergraduate professional training plan of mechanical design and manufacturing and automation,and carries out the exploration and practice of"1+3 teaching resources"integrating into the"One-Student-Two-Tutors"community of undergraduate experimental teaching.On the basis of creating a good learning environment and creating an excellent learning platform,this paper studies the undergraduate experimental teaching of the trinity of"theoretical courses+experimental courses+innovation and entrepreneurship activities,discipline competitions,and scientific research project activities".This study has a certain reference value for colleges and universities to cultivate outstanding engineering talents with happy learning attitude,scientific research interest,practical ability and innovative ability.展开更多
Taking the National Experimental Teaching Demonstration Center of the Central Academy of Drama as an example,this article explores the construction and development of the National Experimental Teaching Demonstration C...Taking the National Experimental Teaching Demonstration Center of the Central Academy of Drama as an example,this article explores the construction and development of the National Experimental Teaching Demonstration Center for the practical teaching of drama and film and television disciplines.The article first introduces the background and importance of the demonstration center and then analyzes in depth the construction content and achievements of the demonstration center from four aspects:practical teaching philosophy,practical teaching system,practical teaching resources,and practical teaching effects.Finally,the article summarizes the experience and shortcomings of the demonstration center and proposes future development directions and suggestions.展开更多
Primary school science is a discipline grounded in experiments,and experimental teaching holds paramount significance in primary school science education in China.Nevertheless,the implementation problems of experiment...Primary school science is a discipline grounded in experiments,and experimental teaching holds paramount significance in primary school science education in China.Nevertheless,the implementation problems of experimental teaching are frequently disregarded.This research endeavors to disclose the concrete challenges encountered by primary school science teachers in the western region of China during the implementation of experimental teaching,analyze their implications,and put forward corresponding mitigatory measures.Based on a questionnaire survey regarding the current state of primary school science experimental teaching in 21 areas of western China,it is unveiled that primary school science teachers in the western region of China confront deficiencies in scientific professional attainment,the necessity to enhance the attitude towards experimental teaching,and a partial shortage of experimental teaching resources.These hardships result in the deterioration of the quality of experimental teaching,the attenuation of students’learning interests,and the exacerbation of teachers’job burnout.Hence,measures should be initiated in aspects such as teacher training,resource development,and enhanced emphasis to assist primary school science teachers in the western region of China in implementing experimental teaching more effectively and elevating the quality of primary school science experimental teaching.展开更多
With the rapid development of information technology and the increasing complexity of the financial market,the teaching methods and means of the Securities Investment course in universities are facing new challenges a...With the rapid development of information technology and the increasing complexity of the financial market,the teaching methods and means of the Securities Investment course in universities are facing new challenges and opportunities.The purpose of this paper is to discuss the application and construction path of virtual simulation experimental teaching in the Securities Investment course.Firstly,it analyses the problems existing in the teaching of traditional securities investment courses,such as the disconnection between theory and practice and the single teaching mode.In order to solve these problems,this paper puts forward the necessity of introducing virtual simulation experimental teaching and details the specific application path of virtual simulation experimental teaching in the Securities Investment course.展开更多
With the reform of experimental teaching in colleges and universities,the teaching mode of"experimental students as the main body,experimental teachers as the guide"needs to constantly explore new experiment...With the reform of experimental teaching in colleges and universities,the teaching mode of"experimental students as the main body,experimental teachers as the guide"needs to constantly explore new experimental teaching methods.In this paper,knowledge graph is integrated into the experiment of mechanical principle to guide undergraduates to use knowledge graph to analyze and summarize independently in experimental teaching activities,aiming at cultivating undergraduates interest in learning and innovative thinking,so as to improve the quality of experimental teaching.This study has a certain reference significance for experimental teaching in colleges and universities.展开更多
Medical Functional Experiment Science, a bridge between basic medicine and clinical medicine, integrates classical experimental teaching contents of three courses including physiology, pathophysiology and pharmacology...Medical Functional Experiment Science, a bridge between basic medicine and clinical medicine, integrates classical experimental teaching contents of three courses including physiology, pathophysiology and pharmacology. This course not only helps students to verify and reinforce theoretical knowledge, but also cultivates their capability of scientific thinking to discover and solve problems. Based on the characteristics of international students and current situation of the teaching platform in the laboratory at Yangtze University, this paper discusses a series of problems in the Medical Functional Experiment Science teaching for international students and puts forward some measures for teaching reform including optimizing experimental content, innovating experimental teaching methods and establishing effective experimental evaluation mode, in order to cultivate more international medical students with innovative ability.展开更多
Aiming at the problems of unclear teaching objectives,obsolete content,and single method in the experimental teaching of university physics at our university,we have implemented a series of reform initiatives.It mainl...Aiming at the problems of unclear teaching objectives,obsolete content,and single method in the experimental teaching of university physics at our university,we have implemented a series of reform initiatives.It mainly includes clarifying the student-centered teaching objectives,optimizing the experimental content,innovating the teaching methods,improving the assessment and evaluation system,and improving the experimental conditions[1,2].After the implementation of the reform,the learning effectiveness of students has been significantly improved,the teaching level of teachers has been significantly enhanced,the curriculum system has been optimized,the efficiency of teaching management has been enhanced,and social recognition has been strengthened.Practice shows that the teaching reform based on the outcome-based education concept effectively improves the quality of university physics experimental teaching and lays the foundation for cultivating innovative talents.展开更多
Virtual simulation experiment,as a new way to promote the digital transformation of education,has a broad development prospect and application value.The civil engineering experimental volume and space are huge,it has ...Virtual simulation experiment,as a new way to promote the digital transformation of education,has a broad development prospect and application value.The civil engineering experimental volume and space are huge,it has a long construction period,is highly dangerous,and is difficult to experiment with.In order to solve the contradiction between the traditional theory teaching of civil engineering and the engineering training of students,the construction of virtual simulation experimental teaching courses with a high degree of realism,intuition,and accuracy can be used as a useful supplement and innovation of experimental and practical teaching.This paper takes the virtual simulation experimental teaching course of urban overpasses as an example,introduces the necessity and practicability of the course construction,and describes the experimental principle structure of the course,the simulation scene design,the experimental teaching process,the experimental method,etc.The course has achieved good application results,and it has been recognized as the first-class virtual simulation teaching course of the Chongqing Municipal Government,which provides certain references to the construction of the same type of courses in the civil engineering profession.展开更多
With the advancement of vocational education reform,education informationization,and digitalization have become the important direction of the reform of electrical and electronic teaching in high vocational colleges.I...With the advancement of vocational education reform,education informationization,and digitalization have become the important direction of the reform of electrical and electronic teaching in high vocational colleges.In this context,intelligent product development of professional electrical and electronic teaching should also do a good job in practice and innovation,especially in actively building a digital experimental teaching platform and promoting the reform of experimental teaching mode,so that students can learn more useful knowledge and skills in the new platform,and cultivate more applied and skilled talents for society.While analyzing the problems existing in the traditional electrical and electronic experimental teaching mode,this paper analyzes the significance and practical path of the construction of electrical and electronic experimental teaching platforms in higher vocational colleges which can be of reference in future research.展开更多
Neuromyelitis optica spectrum disorders are neuroinflammatory demyelinating disorders that lead to permanent visual loss and motor dysfunction.To date,no effective treatment exists as the exact causative mechanism rem...Neuromyelitis optica spectrum disorders are neuroinflammatory demyelinating disorders that lead to permanent visual loss and motor dysfunction.To date,no effective treatment exists as the exact causative mechanism remains unknown.Therefore,experimental models of neuromyelitis optica spectrum disorders are essential for exploring its pathogenesis and in screening for therapeutic targets.Since most patients with neuromyelitis optica spectrum disorders are seropositive for IgG autoantibodies against aquaporin-4,which is highly expressed on the membrane of astrocyte endfeet,most current experimental models are based on aquaporin-4-IgG that initially targets astrocytes.These experimental models have successfully simulated many pathological features of neuromyelitis optica spectrum disorders,such as aquaporin-4 loss,astrocytopathy,granulocyte and macrophage infiltration,complement activation,demyelination,and neuronal loss;however,they do not fully capture the pathological process of human neuromyelitis optica spectrum disorders.In this review,we summarize the currently known pathogenic mechanisms and the development of associated experimental models in vitro,ex vivo,and in vivo for neuromyelitis optica spectrum disorders,suggest potential pathogenic mechanisms for further investigation,and provide guidance on experimental model choices.In addition,this review summarizes the latest information on pathologies and therapies for neuromyelitis optica spectrum disorders based on experimental models of aquaporin-4-IgG-seropositive neuromyelitis optica spectrum disorders,offering further therapeutic targets and a theoretical basis for clinical trials.展开更多
This paper explores the integration of simulation technology in Engineering Mechanics(EM)teaching in vocational colleges.A case study was conducted using the tensile test as an example,and digital resources,such as co...This paper explores the integration of simulation technology in Engineering Mechanics(EM)teaching in vocational colleges.A case study was conducted using the tensile test as an example,and digital resources,such as colored Mises stress nephograms,were obtained.These resources were integrated into the original curriculum to conduct teaching experiments.The results show that the use of digital resources significantly improved the quality of teaching in EM.The integration of simulation technology in EM teaching provides a promising direction for the improvement of vocational education and the cultivation of high-quality skilled talents.The development and application of more simulation-based teaching cases should be studied by scholars.展开更多
Physical chemistry experiments are an important branch of chemical experiments.In view of problems and shortcomings in physical chemistry experiment teaching of food quality and safety major in Chengdu University,the ...Physical chemistry experiments are an important branch of chemical experiments.In view of problems and shortcomings in physical chemistry experiment teaching of food quality and safety major in Chengdu University,the teaching methods of physical chemistry experiment course of food quality and safety major were explored and practiced,aiming to arouse students enthusiasm for experiments and cultivate their ability of independent learning,comprehensive thinking and independent problem solving.展开更多
In order to cultivate excellent clinical medical talents with a solid foundation, strong literacy, refined skills, excellent communication abilities, innovative thinking, and a strong focus on practicality, functional...In order to cultivate excellent clinical medical talents with a solid foundation, strong literacy, refined skills, excellent communication abilities, innovative thinking, and a strong focus on practicality, functional experiments have undergone a series of reforms in areas such as constructing new curriculum systems, improving teaching content, updating teaching equipment, introducing new teaching models, and enhancing teaching evaluation systems.展开更多
At present,rail transit is developing rapidly in the world,and this means new and changing requirements for the training of talents in railway engineering experiments.Given the current problems of limited laboratory/f...At present,rail transit is developing rapidly in the world,and this means new and changing requirements for the training of talents in railway engineering experiments.Given the current problems of limited laboratory/field instruments for railway engineering experimentsand the safety/administrative difficulties of going to the frontline of railway lines to teach railway engineering experiemnts in the field,the Department of Railway Engineering of Central South University tried to introduce virtual reality(VR)technology to teach students experiments in the field of railway engineering.Through the virtualized experimental methods,students can carry out railway engineering experiments such as;vehicle wheel pair off-axis experiments,track geometry and position detection,etc.by immersive means.It was observed that after performing virtual simulation experiments,students appeared conversant in subsequent field experiments.Thus,VR greatly improves the teaching efficiency of railway engineering experiments.展开更多
For mistakes taken in pesticide bioassays, teaching experimental design is improved in the paper, so as to let students explore and analyze in teaching experiments to get a deeper understanding of theoretical knowledg...For mistakes taken in pesticide bioassays, teaching experimental design is improved in the paper, so as to let students explore and analyze in teaching experiments to get a deeper understanding of theoretical knowledge, thereby effectively avoiding frequently-taken mistakes in pesticide bioassays.展开更多
Training students’innovative thinking is an essential task of talent training in colleges and universities,and how to train students’innovativeness in experimental teaching is the focus of modern education.Experimen...Training students’innovative thinking is an essential task of talent training in colleges and universities,and how to train students’innovativeness in experimental teaching is the focus of modern education.Experimental lesson of instrumental analysis is an important section for integrating students’theories and practices,in view of the characteristics of traditional Chinese medicine major and instrumental analysis lesson,this lesson orientates opening up students’innovative thinking,explores the way of improving students’innovative ability in an all-around way through reforming the experimental teaching of instrumental analysis according to the teaching objectives.展开更多
Analysis of Traditional Chinese Medicine is a compulsory comprehensive professional course for Chinese pharmacy major,and it is the necessary knowledge for modern Chinese pharmacy talents.In this paper,the experimenta...Analysis of Traditional Chinese Medicine is a compulsory comprehensive professional course for Chinese pharmacy major,and it is the necessary knowledge for modern Chinese pharmacy talents.In this paper,the experimental teaching of Analysis of Traditional Chinese Medicine under the"five-in-one"practice teaching mode of Guangxi University of Chinese Medicine was explored to provide reference for the experimental teaching of the course Analysis of Traditional Chinese Medicine.展开更多
The experimental course of Landscape Design is based on the training of design ability,which breaks the traditional mode of students'self-completion of homework,and finally changes from the traditional mode of tea...The experimental course of Landscape Design is based on the training of design ability,which breaks the traditional mode of students'self-completion of homework,and finally changes from the traditional mode of teachers'comments to the task of real site design to carry out course experiments,making students construct relevant theoretical knowledge in the process of completing specific projects.After professional designers'in-depth and detailed,systematic analysis and comments,the training of students'professional ability is highlighted.In the process of the experiment,it focuses on link with the industry and enterprises,and obtains the professional abilities and professional skills needed by the enterprises according to the method of situational learning theory.展开更多
In this research the education and training that had been received or wished to be acquired by the Science teachers in the experimental teaching of Biology in high schools, was investigated. It focused on the laborato...In this research the education and training that had been received or wished to be acquired by the Science teachers in the experimental teaching of Biology in high schools, was investigated. It focused on the laboratory practice, didactic methods that can be used in more effective experimental teaching of Biology, pedagogic methods that can be implemented in laboratory team teaching, official and legal issues related to laboratory work and the organization of the seminars, which constituted the dependent variables of a quantitative analysis. A questionnaire consisting of closed type questions was answered by Science teachers of many specialties, who served in Secondary Education at Heraklion Crete prefecture. The asked teachers had not received adequate education in carrying out laboratory exercises of Biology neither during their university studies nor in in-service training. Most of them had taught the course theoretically but a few had carried out laboratory exercises of Biology. The need of training on issues of didactic practices and evaluation was firstly classified, with a significant percentage of methods that can be applied to provoke students' curiosity in scientific issues related to daily life and recognize the value of the Life Sciences by team collaboration and respect of others.展开更多
基金Supported by Undergraduate Teaching Research and Reform Project of University of Shanghai for Science and Technology in 2024(JGXM24281)University-Level First-Class Undergraduate Course Construction Project of University of Shanghai for Science and Technology in 2024(YLKC202424394).
文摘In view of the key role of undergraduate experimental teaching reform in cultivating high-quality talents with both innovative spirit and practical ability,this paper deeply discusses multi-dimensional reform strategies.Specifically,the teaching mode of"double teachers for every student"is innovatively introduced,and scientific research projects are deeply integrated into undergraduate experimental teaching,aiming at realizing the modern development of teaching content and the diversified expansion of teaching methods.By designing and applying the undergraduate experimental teaching platform for intelligent limb rehabilitation training based on the concept of"medical-engineering interdisciplinary crossing",it not only builds a bridge for students to contact cutting-edge scientific research and strengthen practical skills,but also provides valuable ideas and practical models for the innovation of undergraduate experimental teaching.In the future,with the continuous optimization and upgrading of platform functions,it is expected to provide students with a richer and richer learning experience and comprehensively promote students'overall quality.
基金Supported by Undergraduate Teaching Research and Reform Project of University of Shanghai for Science and Technology in 2024(JGXM24281&JGXM24263)First-class Undergraduate Course Construction Project of University of Shanghai for Science and Technology in 2024(YLKC202424394).
文摘This study closely follows the spirit of the first class undergraduate education action plan(2021-2025)of University of Shanghai for Science and Technology,combines with the national first-class undergraduate professional training plan of mechanical design and manufacturing and automation,and carries out the exploration and practice of"1+3 teaching resources"integrating into the"One-Student-Two-Tutors"community of undergraduate experimental teaching.On the basis of creating a good learning environment and creating an excellent learning platform,this paper studies the undergraduate experimental teaching of the trinity of"theoretical courses+experimental courses+innovation and entrepreneurship activities,discipline competitions,and scientific research project activities".This study has a certain reference value for colleges and universities to cultivate outstanding engineering talents with happy learning attitude,scientific research interest,practical ability and innovative ability.
文摘Taking the National Experimental Teaching Demonstration Center of the Central Academy of Drama as an example,this article explores the construction and development of the National Experimental Teaching Demonstration Center for the practical teaching of drama and film and television disciplines.The article first introduces the background and importance of the demonstration center and then analyzes in depth the construction content and achievements of the demonstration center from four aspects:practical teaching philosophy,practical teaching system,practical teaching resources,and practical teaching effects.Finally,the article summarizes the experience and shortcomings of the demonstration center and proposes future development directions and suggestions.
基金The 2023 Sichuan Province Educational Research Project“Research on the Implementation Pathways of Elementary School Science Education under the Background of‘Double Reduction’”(SCJG23A058)。
文摘Primary school science is a discipline grounded in experiments,and experimental teaching holds paramount significance in primary school science education in China.Nevertheless,the implementation problems of experimental teaching are frequently disregarded.This research endeavors to disclose the concrete challenges encountered by primary school science teachers in the western region of China during the implementation of experimental teaching,analyze their implications,and put forward corresponding mitigatory measures.Based on a questionnaire survey regarding the current state of primary school science experimental teaching in 21 areas of western China,it is unveiled that primary school science teachers in the western region of China confront deficiencies in scientific professional attainment,the necessity to enhance the attitude towards experimental teaching,and a partial shortage of experimental teaching resources.These hardships result in the deterioration of the quality of experimental teaching,the attenuation of students’learning interests,and the exacerbation of teachers’job burnout.Hence,measures should be initiated in aspects such as teacher training,resource development,and enhanced emphasis to assist primary school science teachers in the western region of China in implementing experimental teaching more effectively and elevating the quality of primary school science experimental teaching.
基金The 2024 Hankou University School-Level Teaching Reform Research Project“Research on the Application of Virtual Simulation Experimental Teaching in the Course of Securities Investment”(Project number:2024JY43)。
文摘With the rapid development of information technology and the increasing complexity of the financial market,the teaching methods and means of the Securities Investment course in universities are facing new challenges and opportunities.The purpose of this paper is to discuss the application and construction path of virtual simulation experimental teaching in the Securities Investment course.Firstly,it analyses the problems existing in the teaching of traditional securities investment courses,such as the disconnection between theory and practice and the single teaching mode.In order to solve these problems,this paper puts forward the necessity of introducing virtual simulation experimental teaching and details the specific application path of virtual simulation experimental teaching in the Securities Investment course.
基金Supported by Undergraduate Teaching Research and Reform Project of University of Shanghai for Science and Technology in 2024(JGXM24281&JGXM24263)First-class Undergraduate Course Construction Project of University of Shanghai for Science and Technology in 2024(YLKC202424394).
文摘With the reform of experimental teaching in colleges and universities,the teaching mode of"experimental students as the main body,experimental teachers as the guide"needs to constantly explore new experimental teaching methods.In this paper,knowledge graph is integrated into the experiment of mechanical principle to guide undergraduates to use knowledge graph to analyze and summarize independently in experimental teaching activities,aiming at cultivating undergraduates interest in learning and innovative thinking,so as to improve the quality of experimental teaching.This study has a certain reference significance for experimental teaching in colleges and universities.
文摘Medical Functional Experiment Science, a bridge between basic medicine and clinical medicine, integrates classical experimental teaching contents of three courses including physiology, pathophysiology and pharmacology. This course not only helps students to verify and reinforce theoretical knowledge, but also cultivates their capability of scientific thinking to discover and solve problems. Based on the characteristics of international students and current situation of the teaching platform in the laboratory at Yangtze University, this paper discusses a series of problems in the Medical Functional Experiment Science teaching for international students and puts forward some measures for teaching reform including optimizing experimental content, innovating experimental teaching methods and establishing effective experimental evaluation mode, in order to cultivate more international medical students with innovative ability.
基金The 2024 University-Level Higher Education Teaching Reform Project of Guangzhou Xinhua University,“Teaching Reform and Practice Based on OBE Concept:A Case Study of University Physics Experiment”(2024J044)The 2024 University-level Curriculum Teaching and Rresearch Room(Including Virtual Teaching and Research Room)Project of Guangzhou Xinhua University,“University Physics Teaching and Research Office”(2024JYS002)The 2024 University-Level First-Class Undergraduate Major(080714T)Construction Project of Guangzhou Xinhua University(2024YLZY012)。
文摘Aiming at the problems of unclear teaching objectives,obsolete content,and single method in the experimental teaching of university physics at our university,we have implemented a series of reform initiatives.It mainly includes clarifying the student-centered teaching objectives,optimizing the experimental content,innovating the teaching methods,improving the assessment and evaluation system,and improving the experimental conditions[1,2].After the implementation of the reform,the learning effectiveness of students has been significantly improved,the teaching level of teachers has been significantly enhanced,the curriculum system has been optimized,the efficiency of teaching management has been enhanced,and social recognition has been strengthened.Practice shows that the teaching reform based on the outcome-based education concept effectively improves the quality of university physics experimental teaching and lays the foundation for cultivating innovative talents.
基金Chongqing Institute of Technology’s 2022 Virtual Simulation Experiment“Golden Course”Construction Project“Virtual Simulation Experiment of Urban Overpass Vehicle Passage”2023 Teaching Method Reform and“Information Technology+”Smart Teaching Special Research Project Information Technology Multi-Dimensional Research Results of“Enabling Virtual Simulation Experiment Smart Teaching Reform and Practice”。
文摘Virtual simulation experiment,as a new way to promote the digital transformation of education,has a broad development prospect and application value.The civil engineering experimental volume and space are huge,it has a long construction period,is highly dangerous,and is difficult to experiment with.In order to solve the contradiction between the traditional theory teaching of civil engineering and the engineering training of students,the construction of virtual simulation experimental teaching courses with a high degree of realism,intuition,and accuracy can be used as a useful supplement and innovation of experimental and practical teaching.This paper takes the virtual simulation experimental teaching course of urban overpasses as an example,introduces the necessity and practicability of the course construction,and describes the experimental principle structure of the course,the simulation scene design,the experimental teaching process,the experimental method,etc.The course has achieved good application results,and it has been recognized as the first-class virtual simulation teaching course of the Chongqing Municipal Government,which provides certain references to the construction of the same type of courses in the civil engineering profession.
文摘With the advancement of vocational education reform,education informationization,and digitalization have become the important direction of the reform of electrical and electronic teaching in high vocational colleges.In this context,intelligent product development of professional electrical and electronic teaching should also do a good job in practice and innovation,especially in actively building a digital experimental teaching platform and promoting the reform of experimental teaching mode,so that students can learn more useful knowledge and skills in the new platform,and cultivate more applied and skilled talents for society.While analyzing the problems existing in the traditional electrical and electronic experimental teaching mode,this paper analyzes the significance and practical path of the construction of electrical and electronic experimental teaching platforms in higher vocational colleges which can be of reference in future research.
文摘Neuromyelitis optica spectrum disorders are neuroinflammatory demyelinating disorders that lead to permanent visual loss and motor dysfunction.To date,no effective treatment exists as the exact causative mechanism remains unknown.Therefore,experimental models of neuromyelitis optica spectrum disorders are essential for exploring its pathogenesis and in screening for therapeutic targets.Since most patients with neuromyelitis optica spectrum disorders are seropositive for IgG autoantibodies against aquaporin-4,which is highly expressed on the membrane of astrocyte endfeet,most current experimental models are based on aquaporin-4-IgG that initially targets astrocytes.These experimental models have successfully simulated many pathological features of neuromyelitis optica spectrum disorders,such as aquaporin-4 loss,astrocytopathy,granulocyte and macrophage infiltration,complement activation,demyelination,and neuronal loss;however,they do not fully capture the pathological process of human neuromyelitis optica spectrum disorders.In this review,we summarize the currently known pathogenic mechanisms and the development of associated experimental models in vitro,ex vivo,and in vivo for neuromyelitis optica spectrum disorders,suggest potential pathogenic mechanisms for further investigation,and provide guidance on experimental model choices.In addition,this review summarizes the latest information on pathologies and therapies for neuromyelitis optica spectrum disorders based on experimental models of aquaporin-4-IgG-seropositive neuromyelitis optica spectrum disorders,offering further therapeutic targets and a theoretical basis for clinical trials.
基金Science and Technology Key Project of Beijing Polytechnic(Project number:2024X008-KXZ)。
文摘This paper explores the integration of simulation technology in Engineering Mechanics(EM)teaching in vocational colleges.A case study was conducted using the tensile test as an example,and digital resources,such as colored Mises stress nephograms,were obtained.These resources were integrated into the original curriculum to conduct teaching experiments.The results show that the use of digital resources significantly improved the quality of teaching in EM.The integration of simulation technology in EM teaching provides a promising direction for the improvement of vocational education and the cultivation of high-quality skilled talents.The development and application of more simulation-based teaching cases should be studied by scholars.
文摘Physical chemistry experiments are an important branch of chemical experiments.In view of problems and shortcomings in physical chemistry experiment teaching of food quality and safety major in Chengdu University,the teaching methods of physical chemistry experiment course of food quality and safety major were explored and practiced,aiming to arouse students enthusiasm for experiments and cultivate their ability of independent learning,comprehensive thinking and independent problem solving.
文摘In order to cultivate excellent clinical medical talents with a solid foundation, strong literacy, refined skills, excellent communication abilities, innovative thinking, and a strong focus on practicality, functional experiments have undergone a series of reforms in areas such as constructing new curriculum systems, improving teaching content, updating teaching equipment, introducing new teaching models, and enhancing teaching evaluation systems.
基金Education and Teaching Reform Project of Central South University(2019jy097).
文摘At present,rail transit is developing rapidly in the world,and this means new and changing requirements for the training of talents in railway engineering experiments.Given the current problems of limited laboratory/field instruments for railway engineering experimentsand the safety/administrative difficulties of going to the frontline of railway lines to teach railway engineering experiemnts in the field,the Department of Railway Engineering of Central South University tried to introduce virtual reality(VR)technology to teach students experiments in the field of railway engineering.Through the virtualized experimental methods,students can carry out railway engineering experiments such as;vehicle wheel pair off-axis experiments,track geometry and position detection,etc.by immersive means.It was observed that after performing virtual simulation experiments,students appeared conversant in subsequent field experiments.Thus,VR greatly improves the teaching efficiency of railway engineering experiments.
基金Supported by Construction Project of " National Teaching Team of Plant Protection" in 2008Construction Project of National " Plant Protection Specialty"( TS11138)Provincial Excellent Course Construction Project of Pesticide Science in Yunnan Province
文摘For mistakes taken in pesticide bioassays, teaching experimental design is improved in the paper, so as to let students explore and analyze in teaching experiments to get a deeper understanding of theoretical knowledge, thereby effectively avoiding frequently-taken mistakes in pesticide bioassays.
基金Project for the Innovation Planning of Guangxi Graduates Education(JGY2020108,JGY2019103)。
文摘Training students’innovative thinking is an essential task of talent training in colleges and universities,and how to train students’innovativeness in experimental teaching is the focus of modern education.Experimental lesson of instrumental analysis is an important section for integrating students’theories and practices,in view of the characteristics of traditional Chinese medicine major and instrumental analysis lesson,this lesson orientates opening up students’innovative thinking,explores the way of improving students’innovative ability in an all-around way through reforming the experimental teaching of instrumental analysis according to the teaching objectives.
基金Supported by National First-class Undergraduate MajorEducation and Teaching Reform and Research Project of College of Pharmacy,Guangxi University of Chinese Medicine in 2021.
文摘Analysis of Traditional Chinese Medicine is a compulsory comprehensive professional course for Chinese pharmacy major,and it is the necessary knowledge for modern Chinese pharmacy talents.In this paper,the experimental teaching of Analysis of Traditional Chinese Medicine under the"five-in-one"practice teaching mode of Guangxi University of Chinese Medicine was explored to provide reference for the experimental teaching of the course Analysis of Traditional Chinese Medicine.
基金Construction Project of Landscape Architecture Major of Colleges and Universities in Guangdong Province[YueJiaoGaoHan(2020)19].
文摘The experimental course of Landscape Design is based on the training of design ability,which breaks the traditional mode of students'self-completion of homework,and finally changes from the traditional mode of teachers'comments to the task of real site design to carry out course experiments,making students construct relevant theoretical knowledge in the process of completing specific projects.After professional designers'in-depth and detailed,systematic analysis and comments,the training of students'professional ability is highlighted.In the process of the experiment,it focuses on link with the industry and enterprises,and obtains the professional abilities and professional skills needed by the enterprises according to the method of situational learning theory.
文摘In this research the education and training that had been received or wished to be acquired by the Science teachers in the experimental teaching of Biology in high schools, was investigated. It focused on the laboratory practice, didactic methods that can be used in more effective experimental teaching of Biology, pedagogic methods that can be implemented in laboratory team teaching, official and legal issues related to laboratory work and the organization of the seminars, which constituted the dependent variables of a quantitative analysis. A questionnaire consisting of closed type questions was answered by Science teachers of many specialties, who served in Secondary Education at Heraklion Crete prefecture. The asked teachers had not received adequate education in carrying out laboratory exercises of Biology neither during their university studies nor in in-service training. Most of them had taught the course theoretically but a few had carried out laboratory exercises of Biology. The need of training on issues of didactic practices and evaluation was firstly classified, with a significant percentage of methods that can be applied to provoke students' curiosity in scientific issues related to daily life and recognize the value of the Life Sciences by team collaboration and respect of others.