Game theory is extensively used to study strategy-making and actions of play- ers. The authors proposed an analysis method for study the evolutionary outcome and behaviors of players with preference in iterated priso...Game theory is extensively used to study strategy-making and actions of play- ers. The authors proposed an analysis method for study the evolutionary outcome and behaviors of players with preference in iterated prisoner's dilemma. In this article, a preference parameter k was introduced in the payoff matrix, wherein the value of k denotes the player's degree of egoism and altruism (preference). Then, a game-theoretic dynamical model was formulated using Birth-and-Death process. The authors studied how preference influences the evolutionary equilibrium and behaviors of players. The authors get the general results: egoism leads to defection, and altruism can make players build trust and maintain cooperation, and so, the hope of the Pareto optimal solution. In the end, the simulation experiments proved the efficiency of the method.展开更多
BACKGROUND Inflammatory bowel disease(IBD)patients’expectations of treatment outcomes may differ by ethnicity.AIM To investigate treatment preferences of Jewish and Arabs patients.METHODS This prospective survey rank...BACKGROUND Inflammatory bowel disease(IBD)patients’expectations of treatment outcomes may differ by ethnicity.AIM To investigate treatment preferences of Jewish and Arabs patients.METHODS This prospective survey ranked outcomes treatment preferences among Arab IBD patients,based on the 10 IBD-disk items compared to historical data of Jews.An anonymous questionnaire in either Arabic or Hebrew was distributed among IBD patients.Patients were required to rank 10 statements describing different aspects of IBD according to their importance to the patients as treatment goals.Answers were compared to the answers of a historical group of Jewish patients.RESULTS IBD-disk items of 121 Arabs were compared to 240 Jewish patients.The Jewish patients included more females,[151(62.9%)vs 52(43.3%);P<0.001],higher education level(P=0.02),more urban residence[188(78.3%)vs 54(45.4%);P<0.001],less unemployment[52(21.7%)vs 41(33.9%);P=0.012],higher income level(P<0.001),and more in a partnership[162(67.8%)vs 55(45.4%);P<0.001].Expectations regarding disease symptoms:abdominal pain,energy,and regular defecation ranked highest for both groups.Arabs gave significantly lower rankings(range 4.29-6.69)than Jewish patients(range 6.25-9.03)regarding all items,except for body image.Compared to Arab women,Jewish women attached higher priority to abdominal pain,energy,education/work,sleep,and joint pain.Multivariable regression analysis revealed that higher patient preferences were associated with Jewish ethnicity(OR 4.77;95%CI 2.36-9.61,P<0.001)and disease activity.The more active the disease,the greater the odds ratio for higher ranking of the questionnaire items(1-2 attacks per year:OR 2.13;95%CI 1.02-4.45,P=0.043;and primarily active disease:OR 5.29;95%CI 2.30-12.18,P<0.001).Factors inversely associated with higher patient preference were male gender(OR 0.5;95%CI 0.271-0.935,P=0.030),UC(OR 0.444;95%CI 0.241-0.819,P=0.009),and above average income level(OR 0.267;95%CI:0.124-0.577,P=0.001).CONCLUSION The highest priority for treatment outcomes was symptom relief.,Patients preferences were impacted by ethnicity,gender,and socio-economic disparity.Understanding patients'priorities may improve communication and enable a personalized approach.展开更多
With stepwise development of Chinese enterprise,management problem is increasingly prominent,especially human resource management issues. Facing international environment of entering into World Trade Organization,the ...With stepwise development of Chinese enterprise,management problem is increasingly prominent,especially human resource management issues. Facing international environment of entering into World Trade Organization,the country accelerates construction pace of human resource management subject in colleges and universities,which provides professional channel for management efficiency and market competition ability of Chinese enterprise,but it is still far from practice. In this paper,the concept,origin and inhibition factors of ingroup preference are elaborated. Based on the visual angle of ingroup preference,started from four dimensions( enterprise incentive system,talent management idea,psychological contract and employee communication consciousness),main problems existing in employee relationship management of modern enterprise are explored. It is specially emphasized that manager often holds the blame in front of dealing with the crisis after contradiction,which is " fatal point" neglected in employee relationship management of modern enterprise. To improve its core competitive power,enterprise must value harmonious relationship with employees.展开更多
BACKGROUND Patients with Crohn’s disease(CD)are at risk of developing complications such as perianal fistulas.Patients with Crohn’s perianal fistulas(CPF)are affected by fecal incontinence(FI),bleeding,pain,swelling...BACKGROUND Patients with Crohn’s disease(CD)are at risk of developing complications such as perianal fistulas.Patients with Crohn’s perianal fistulas(CPF)are affected by fecal incontinence(FI),bleeding,pain,swelling,and purulent perianal discharge,and METHODS This cross-sectional observational study was conducted in patients with CD aged 21-90 years via a web-enabled questionnaire in seven countries(April-August 2021).Patients were recruited into three cohorts:Cohort 1 included patients without perianal fistulas;cohort 2 included patients with perianal fistulas without fistula-related surgery;and cohort 3 included patients with perianal fistulas and fistula-related surgery.Validated patient-reported outcome measures were used to assess quality of life.Drivers of treatment preferences were measured using a discrete choice experiment(DCE).RESULTS In total,929 patients were recruited(cohort 1,n=620;cohort 2,n=174;cohort 3,n=135).Short Inflammatory Bowel Disease Questionnaire scores were worse for patients with CPF(cohorts 2 and 3)than for those with CD without CPF(cohort 1):Mean score 3.8 and 3.7 vs 4.1,respectively,(P<0.001).Similarly,mean Revised FI and FI Quality of Life scores were worse for patients with CPF than for those with CD without CPF.Quality of Life with Anal Fistula scores were similar in patients with CPF with or without CPF-related surgery(cohorts 2 and 3):Mean score 41 and 42,respectively.In the DCE,postoperative discomfort and fistula healing rate were the most important treatment attributes influencing treatment choice:Mean relative importance 35.7 and 24.7,respectively.CONCLUSION The burden of illness in CD is significantly higher for patients with CPF and patients rate lower postoperative discomfort and higher healing rates as the most desirable treatment attributes.展开更多
Cervicogenic headache(CEH)has been recognized as a unique category of headache that can be difficult to diagnose and treat.In China,CEH patients are managed by many different specialties,and the treatment plans remain...Cervicogenic headache(CEH)has been recognized as a unique category of headache that can be difficult to diagnose and treat.In China,CEH patients are managed by many different specialties,and the treatment plans remain controversial.Therefore,there is a great need for comprehensive evidence-based Chinese experts’recommendations for the management of CEH.The Chinese Association for the Study of Pain asked an expert panel to develop recommendations for a series of questions that are essential for daily clinical management of patients with CEH.A group of multidisciplinary Chinese Association for the Study of Pain experts identified the clinically relevant topics in CEH.A systematic review of the literature was performed,and evidence supporting the benefits and harms for the management of CEH was summarized.Twenty-four recommendations were finally developed through expert consensus voting for evidence quality and recommendation strength.We hope this guideline provides direction for clinicians and patients making treatment decisions for the management of CEH.展开更多
The implementation of strategies to achieve the Sustainable Development Goals(SDGs)is frequently hindered by potential trade-offs between priorities for either environmental protection or human well-being.However,ecos...The implementation of strategies to achieve the Sustainable Development Goals(SDGs)is frequently hindered by potential trade-offs between priorities for either environmental protection or human well-being.However,ecosystem services(ES)-based solutions can offer possible co-benefits for SDGs implementation that are often overlooked or underexploited.In this study,we cover this gap and investigate how experts from different countries value the SDGs and relate them with ES.A total of 66 countries participated to the survey,and answers were grouped into three macro-regions:Asia;Europe,North America,and Oceania(ENO);Latin America,Caribbean and Africa(LA).Results show that the most prioritized SDGs in the three macro-regions are usually those related to essential material needs and environmental conditions,such as SDG2(Zero Hunger),SDG1(No Poverty),and SDG6(Clean Water).At a global scale,the number of prioritized synergies between SDGs and ES largely exceeded trade-offs.The highest amount of synergies was observed for SDG1(No Poverty),mainly with SDG2,SDG3(Good Health),SDG5(Gender Equality),and SDG8(Economic Growth).Other major synergies among SDGs include SDG14-15(Life below water-Life on land),SDG5-10(Gender Equity-Reduced Inequality),and SDG1-2(No poverty-Zero Hunger).At a global scale,SDG15,SDG13,SDG14,and SDG6 were closely related to ES like climate regulation,freshwater,food,water purification,biodiversity,and education.SDG11(Sustainable Cities)and SDG3 were also relevant in Asia and in LA,respectively.Overall,this study shows the potential to couple future policies that can implement SDGs’strategies while adopting ES-based solutions in different regions of the world.展开更多
Toyamara Da Vera Cruz is all ears when Peng Yansen, her teacher, glves instructions. Although she has extensive experience in farming herself. coming from a long line of livestock breeders, Cruz is now learning a new ...Toyamara Da Vera Cruz is all ears when Peng Yansen, her teacher, glves instructions. Although she has extensive experience in farming herself. coming from a long line of livestock breeders, Cruz is now learning a new skill from Peng.展开更多
CO2捕集和封存技术(Carbon Capture and Storage,CCS)作为我国应对气候变化三大措施之一,是重要的战略技术储备。目前我国CCS主要是以政府引导、联合开展示范性工程为主,而CCS全流程示范涉及内部各要素的选择和组合问题。为更好地统筹规...CO2捕集和封存技术(Carbon Capture and Storage,CCS)作为我国应对气候变化三大措施之一,是重要的战略技术储备。目前我国CCS主要是以政府引导、联合开展示范性工程为主,而CCS全流程示范涉及内部各要素的选择和组合问题。为更好地统筹规划CCS全流程技术示范,亟需从现有技术成熟度、我国技术掌握水平、技术发展前景以及成本、风险、目标一致性、技术涵盖性、现实性等方面选取合适的CCS技术组合。本研究通过问卷调查和面对面访谈的方式对140位专家关于CCS全流程示范技术的偏好进行研究,采用联合分析法,分析专家对CCS技术的接受和偏好程度。结果表明,专家认为封存方式是CCS技术发展中最重要的因素,其次是捕集方式和运输方式。同时我们发现,来自不同部门的专家对CCS技术发展的看法不太一样。最后,通过分析筛选出近10种全流程CCS技术组合。展开更多
基金supported by National Natural Science Foundation of China(60574071)
文摘Game theory is extensively used to study strategy-making and actions of play- ers. The authors proposed an analysis method for study the evolutionary outcome and behaviors of players with preference in iterated prisoner's dilemma. In this article, a preference parameter k was introduced in the payoff matrix, wherein the value of k denotes the player's degree of egoism and altruism (preference). Then, a game-theoretic dynamical model was formulated using Birth-and-Death process. The authors studied how preference influences the evolutionary equilibrium and behaviors of players. The authors get the general results: egoism leads to defection, and altruism can make players build trust and maintain cooperation, and so, the hope of the Pareto optimal solution. In the end, the simulation experiments proved the efficiency of the method.
文摘BACKGROUND Inflammatory bowel disease(IBD)patients’expectations of treatment outcomes may differ by ethnicity.AIM To investigate treatment preferences of Jewish and Arabs patients.METHODS This prospective survey ranked outcomes treatment preferences among Arab IBD patients,based on the 10 IBD-disk items compared to historical data of Jews.An anonymous questionnaire in either Arabic or Hebrew was distributed among IBD patients.Patients were required to rank 10 statements describing different aspects of IBD according to their importance to the patients as treatment goals.Answers were compared to the answers of a historical group of Jewish patients.RESULTS IBD-disk items of 121 Arabs were compared to 240 Jewish patients.The Jewish patients included more females,[151(62.9%)vs 52(43.3%);P<0.001],higher education level(P=0.02),more urban residence[188(78.3%)vs 54(45.4%);P<0.001],less unemployment[52(21.7%)vs 41(33.9%);P=0.012],higher income level(P<0.001),and more in a partnership[162(67.8%)vs 55(45.4%);P<0.001].Expectations regarding disease symptoms:abdominal pain,energy,and regular defecation ranked highest for both groups.Arabs gave significantly lower rankings(range 4.29-6.69)than Jewish patients(range 6.25-9.03)regarding all items,except for body image.Compared to Arab women,Jewish women attached higher priority to abdominal pain,energy,education/work,sleep,and joint pain.Multivariable regression analysis revealed that higher patient preferences were associated with Jewish ethnicity(OR 4.77;95%CI 2.36-9.61,P<0.001)and disease activity.The more active the disease,the greater the odds ratio for higher ranking of the questionnaire items(1-2 attacks per year:OR 2.13;95%CI 1.02-4.45,P=0.043;and primarily active disease:OR 5.29;95%CI 2.30-12.18,P<0.001).Factors inversely associated with higher patient preference were male gender(OR 0.5;95%CI 0.271-0.935,P=0.030),UC(OR 0.444;95%CI 0.241-0.819,P=0.009),and above average income level(OR 0.267;95%CI:0.124-0.577,P=0.001).CONCLUSION The highest priority for treatment outcomes was symptom relief.,Patients preferences were impacted by ethnicity,gender,and socio-economic disparity.Understanding patients'priorities may improve communication and enable a personalized approach.
文摘With stepwise development of Chinese enterprise,management problem is increasingly prominent,especially human resource management issues. Facing international environment of entering into World Trade Organization,the country accelerates construction pace of human resource management subject in colleges and universities,which provides professional channel for management efficiency and market competition ability of Chinese enterprise,but it is still far from practice. In this paper,the concept,origin and inhibition factors of ingroup preference are elaborated. Based on the visual angle of ingroup preference,started from four dimensions( enterprise incentive system,talent management idea,psychological contract and employee communication consciousness),main problems existing in employee relationship management of modern enterprise are explored. It is specially emphasized that manager often holds the blame in front of dealing with the crisis after contradiction,which is " fatal point" neglected in employee relationship management of modern enterprise. To improve its core competitive power,enterprise must value harmonious relationship with employees.
文摘BACKGROUND Patients with Crohn’s disease(CD)are at risk of developing complications such as perianal fistulas.Patients with Crohn’s perianal fistulas(CPF)are affected by fecal incontinence(FI),bleeding,pain,swelling,and purulent perianal discharge,and METHODS This cross-sectional observational study was conducted in patients with CD aged 21-90 years via a web-enabled questionnaire in seven countries(April-August 2021).Patients were recruited into three cohorts:Cohort 1 included patients without perianal fistulas;cohort 2 included patients with perianal fistulas without fistula-related surgery;and cohort 3 included patients with perianal fistulas and fistula-related surgery.Validated patient-reported outcome measures were used to assess quality of life.Drivers of treatment preferences were measured using a discrete choice experiment(DCE).RESULTS In total,929 patients were recruited(cohort 1,n=620;cohort 2,n=174;cohort 3,n=135).Short Inflammatory Bowel Disease Questionnaire scores were worse for patients with CPF(cohorts 2 and 3)than for those with CD without CPF(cohort 1):Mean score 3.8 and 3.7 vs 4.1,respectively,(P<0.001).Similarly,mean Revised FI and FI Quality of Life scores were worse for patients with CPF than for those with CD without CPF.Quality of Life with Anal Fistula scores were similar in patients with CPF with or without CPF-related surgery(cohorts 2 and 3):Mean score 41 and 42,respectively.In the DCE,postoperative discomfort and fistula healing rate were the most important treatment attributes influencing treatment choice:Mean relative importance 35.7 and 24.7,respectively.CONCLUSION The burden of illness in CD is significantly higher for patients with CPF and patients rate lower postoperative discomfort and higher healing rates as the most desirable treatment attributes.
文摘Cervicogenic headache(CEH)has been recognized as a unique category of headache that can be difficult to diagnose and treat.In China,CEH patients are managed by many different specialties,and the treatment plans remain controversial.Therefore,there is a great need for comprehensive evidence-based Chinese experts’recommendations for the management of CEH.The Chinese Association for the Study of Pain asked an expert panel to develop recommendations for a series of questions that are essential for daily clinical management of patients with CEH.A group of multidisciplinary Chinese Association for the Study of Pain experts identified the clinically relevant topics in CEH.A systematic review of the literature was performed,and evidence supporting the benefits and harms for the management of CEH was summarized.Twenty-four recommendations were finally developed through expert consensus voting for evidence quality and recommendation strength.We hope this guideline provides direction for clinicians and patients making treatment decisions for the management of CEH.
基金This work was supported by National Key R&D Program of China(Grant No.2017YFA0604700)National Natural Science Foundation of China(Grant No.4181101243)+2 种基金the Fundamental Research Funds for the Central UniversitiesFrancesco Cherubini was supported by Nor-wegian Research Council(Grant No.286773)Paulo Pereira was sup-ported by the European Social Fund project LINESAM(Grant No.09.3.3-LMT-K-712-01-0104).
文摘The implementation of strategies to achieve the Sustainable Development Goals(SDGs)is frequently hindered by potential trade-offs between priorities for either environmental protection or human well-being.However,ecosystem services(ES)-based solutions can offer possible co-benefits for SDGs implementation that are often overlooked or underexploited.In this study,we cover this gap and investigate how experts from different countries value the SDGs and relate them with ES.A total of 66 countries participated to the survey,and answers were grouped into three macro-regions:Asia;Europe,North America,and Oceania(ENO);Latin America,Caribbean and Africa(LA).Results show that the most prioritized SDGs in the three macro-regions are usually those related to essential material needs and environmental conditions,such as SDG2(Zero Hunger),SDG1(No Poverty),and SDG6(Clean Water).At a global scale,the number of prioritized synergies between SDGs and ES largely exceeded trade-offs.The highest amount of synergies was observed for SDG1(No Poverty),mainly with SDG2,SDG3(Good Health),SDG5(Gender Equality),and SDG8(Economic Growth).Other major synergies among SDGs include SDG14-15(Life below water-Life on land),SDG5-10(Gender Equity-Reduced Inequality),and SDG1-2(No poverty-Zero Hunger).At a global scale,SDG15,SDG13,SDG14,and SDG6 were closely related to ES like climate regulation,freshwater,food,water purification,biodiversity,and education.SDG11(Sustainable Cities)and SDG3 were also relevant in Asia and in LA,respectively.Overall,this study shows the potential to couple future policies that can implement SDGs’strategies while adopting ES-based solutions in different regions of the world.
文摘Toyamara Da Vera Cruz is all ears when Peng Yansen, her teacher, glves instructions. Although she has extensive experience in farming herself. coming from a long line of livestock breeders, Cruz is now learning a new skill from Peng.
文摘CO2捕集和封存技术(Carbon Capture and Storage,CCS)作为我国应对气候变化三大措施之一,是重要的战略技术储备。目前我国CCS主要是以政府引导、联合开展示范性工程为主,而CCS全流程示范涉及内部各要素的选择和组合问题。为更好地统筹规划CCS全流程技术示范,亟需从现有技术成熟度、我国技术掌握水平、技术发展前景以及成本、风险、目标一致性、技术涵盖性、现实性等方面选取合适的CCS技术组合。本研究通过问卷调查和面对面访谈的方式对140位专家关于CCS全流程示范技术的偏好进行研究,采用联合分析法,分析专家对CCS技术的接受和偏好程度。结果表明,专家认为封存方式是CCS技术发展中最重要的因素,其次是捕集方式和运输方式。同时我们发现,来自不同部门的专家对CCS技术发展的看法不太一样。最后,通过分析筛选出近10种全流程CCS技术组合。