2007 has already said farewell to us,however,the influences and meditations it brought are still fresh.In the past year, Chinese textile industry has waved through ups and downs:increasing austerity of external enviro...2007 has already said farewell to us,however,the influences and meditations it brought are still fresh.In the past year, Chinese textile industry has waved through ups and downs:increasing austerity of external environment and adjustment of internal policies seemingly kept squeezing its profit margin,even the living space. But,to everyone’s gratification, many Chinese textile industries survived from diversity and carved out ways through twists and turns.However,while we were ready to breathe for relief,the snow of 2008 once again triggered people’s worries,and the continuing CPI growth as well as RMB appreciation circumstance,many export-oriented enterprises,like riding a tiger,are tortured by the idea whether do textile business or not, if do,how.Fortunately, some enterprise began to turn their attention to domestic market and pay more efforts to brand building and technology innovation with intends to develop new markets……展开更多
China’s swift and substantial economic growth over the past 20 years has made the country one of the top industrial powers in the world, second only the United States. From the perspective of ecology and the impact o...China’s swift and substantial economic growth over the past 20 years has made the country one of the top industrial powers in the world, second only the United States. From the perspective of ecology and the impact on the environment produced by economic and industrial growth, the exports that have driven rapid growth have also resulted in an alarming level of environmental pollution in major Chinese cities. Research has shown that the Chinese government’s investment in bringing down pollution levels has been insufficient and ineffective. The monetary amount allocated for pollution reduction has barely reached 0.15% of the country’s GDP and has failed to meaningfully reverse the effects of industrialization, including increased exports and economic growth rates affecting China’s ecology. The present study investigated China’s ecological situation in terms of the industrial production that has generated its level of exports, with special focus on problems related to water, air, and solid waste. An econometric analysis was conducted to determine the relationship between the main variables. The exports and GDP (dependent variable), air pollution, water pollution, and industrial solid waste (independent variables) were provided by the Institute of Statistics and the Environment Institute of China for this study. The data was managed in Econometric Eviews 7.0 software and yielded an adjusted R<sup>2 </sup>of 96.09% (high correlation) with an interesting correlation between the exports and three independent variables;after subsequent variable analysis, we found that investments in water and industrial solid waste were not significant (i.e., that said investments have failed to solve the pollution problem). It is necessary to review the Chinese investment policy with special attention to these variables to appropriately respond to China’s ecological crisis.展开更多
The study examined the causal relationship between export and economic growth based on monthly data for the period 2010 to 2019. Composite Index Economic Activity (CIEA) was used as a proxy for real GDP (economic grow...The study examined the causal relationship between export and economic growth based on monthly data for the period 2010 to 2019. Composite Index Economic Activity (CIEA) was used as a proxy for real GDP (economic growth). </span><span style="font-family:Verdana;">Time series</span><span style="font-family:Verdana;"> econometric techniques were employed to explore long-run and </span><span style="font-family:Verdana;">short run</span><span style="font-family:Verdana;"> relationships as well as the causality between them.</span><span style="font-family:Verdana;"> </span><span style="font-family:Verdana;">The results revealed the existence of long-run relationships;evidence of bi-directional causality and a rapid adjustment to equilibrium between real GDP and exports. Recommendations </span></span><span style="font-family:Verdana;">are</span><span style="font-family:""> <span style="font-family:Verdana;">that,</span> <span style="font-family:Verdana;">policy makers</span><span style="font-family:Verdana;"> should focus on implementing </span><span style="font-family:Verdana;">export oriented</span><span style="font-family:Verdana;"> policies and promote economic growth to achieve sustainable development.展开更多
Imports and exports In the period of January-October,Chinese imports and exports have maintained rapid growth,the structure has continued to be optimized,the transformation of growth drivers has been accelerated,the q...Imports and exports In the period of January-October,Chinese imports and exports have maintained rapid growth,the structure has continued to be optimized,the transformation of growth drivers has been accelerated,the quality and efficiency have improved,and momentum of steady growth has been further consolidated.展开更多
China’s foreign trade in 2015 2015 was a very unusual year in the history of China’s foreign trade,the situation became more complicated,and downward pressure increased significantly.According to Customs figures,Ch...China’s foreign trade in 2015 2015 was a very unusual year in the history of China’s foreign trade,the situation became more complicated,and downward pressure increased significantly.According to Customs figures,China’s total import and export in 2015 reached 24.58 trillion yuan,down 7%year on year(the same below).Export was 14.14 trillion yuan,down 1.8%,and import 10.45 trillion yuan。展开更多
Along with the rapid development of its foreign trade, China’s food imports and exports have also increased by a large margin in recent years. In 1994, the total value of imports and exports of food in the country re...Along with the rapid development of its foreign trade, China’s food imports and exports have also increased by a large margin in recent years. In 1994, the total value of imports and exports of food in the country reached US$12.展开更多
China will take comprehensive measures next year to ensure a stable textile export growth, the Ministry of Commerce (MOFCOM) said. Since the country ’s textile export faces complex situation amid a world economy slow...China will take comprehensive measures next year to ensure a stable textile export growth, the Ministry of Commerce (MOFCOM) said. Since the country ’s textile export faces complex situation amid a world economy slowdown and financial turmoil,展开更多
Since reform and opening-up in 1978, changes in China's industrial structure have generally followed the pattern of "Kuznets facts" but still exhibits some unique characteristics, which led us to raise t...Since reform and opening-up in 1978, changes in China's industrial structure have generally followed the pattern of "Kuznets facts" but still exhibits some unique characteristics, which led us to raise the following three questions regarding China's structural transformation:(1) Why did the share of China's agricultural and manufacturing employment reduce/increase intermittently rather than continuously?(2) Why did the share of China's agricultural employment increase during certain periods? When the share of manufacturing employment reduced, why did the workforce reversely flow into agriculture rather than move to the service sector?(3) Why did growth in the share of China's service sector employment decelerate before reaching its peak? Why did the share of employment in the industrial sector suddenly increase after an abrupt decline? This paper creates a multisector economic growth model that contains non-homothetic preferences and differentiated productivity, and incorporates the "two drivers" therein for a demand-side estimation and analysis. The result shows that China's economic growth model driven by net export and investment is a critical factor for explaining the three questions regarding its structural transformation. This paper believes that only by implementing supply-side structural reforms, reducing the dependence on net export and investment, and achieving sustainable endogenous economic growth will China be able to expedite its industrial restructuring.展开更多
The purpose of this review is to communicate the research results of Chinese academia in this field to interested scholars in Western academia.Our review question is:What were the factors that positively or negatively...The purpose of this review is to communicate the research results of Chinese academia in this field to interested scholars in Western academia.Our review question is:What were the factors that positively or negatively influenced China’s export?We designed a systematic review protocol and then conducted a seven-round in-depth search.After the searching and checking process,a database of 620 academic journal articles was created.Altogether,we find 269 factors have boosted or hindered China’s export.Majority of researches focused on macro level factors.Very few papers studied the firm level or individual level factors.Based on our database,several most frequently studied factors that affect China’s export are identified.In the end,a future research direction is proposed.展开更多
China’s foreign trade in November 2014According to Customs figures,China’s total import and export in November last year reached 2.2681trillion yuan,down 0.3%year on year(the same below).Export was 1.3014trillion yu...China’s foreign trade in November 2014According to Customs figures,China’s total import and export in November last year reached 2.2681trillion yuan,down 0.3%year on year(the same below).Export was 1.3014trillion yuan,up 4.9%,and import0.9666 trillion yuan,down 6.5%.Trade surplus was 334.8 billion yuan,up60.5%.In terms of the U.S.dollar,the total import and export in September2014 reached US$368.85 billion,down 0.5%,among which,export展开更多
Yunnan Province is the bridgehead for the opening of the southwest region in China,and the economic frontier of China-ASEAN economic cooperation,where the export of agricultural products plays an important role in pro...Yunnan Province is the bridgehead for the opening of the southwest region in China,and the economic frontier of China-ASEAN economic cooperation,where the export of agricultural products plays an important role in promoting the openness of the southwest region and strengthening China-ASEAN economic cooperation.In this paper,we use CMS model to analyze causes of the increase in the exports of agricultural products in Yunnan Province during the period 2001-2010.It is found that the expanded import scale of agricultural products in the world,improvement in the export competitiveness of products and the adaption of product export structure to the changes in the structure of world import demand,are the main factors responsible for increase in the exports of agricultural products in Yunnan Province.In recent years, the improvement of competitiveness of the export of agricultural products becomes a key factor for the growth of the export of agricultural products in Yunnan Province.In terms of the products classified,strong export competitiveness has promoted the export of plant products,such as beverages and tobacco,while weak export competitiveness and unreasonable export structure has impeded the export of animal products,plant and animal oil and fat products.展开更多
In recent years,growth hormone and insulin-like growth factors have become key regulators of bone metabolism and remodeling,crucial for maintaining healthy bone mass throughout life.Studies have shown that adult growt...In recent years,growth hormone and insulin-like growth factors have become key regulators of bone metabolism and remodeling,crucial for maintaining healthy bone mass throughout life.Studies have shown that adult growth hormone deficiency leads to alterations in bone remodeling,significantly affecting bone microarchitecture and increasing fracture risk.Although recombinant human growth hormone replacement therapy can mitigate these adverse effects,improving bone density,and reduce fracture risk,its effectiveness in treating osteoporosis,especially in adults with established growth hormone deficiency,seems limited.Bisphosphonates inhibit bone resorption by targeting farnesyl pyrophosphate synthase in osteoclasts,and clinical trials have confirmed their efficacy in improving osteoporosis.Therefore,for adult growth hormone deficiency patients with osteoporosis,the use of bisphosphonates alongside growth hormone replacement therapy is recommended.展开更多
After entering into WTO,export volume of agricultural products in China quickly increases,but its proportion in total trade volume becomes lower and lower,and there are more and more trade barriers of agricultural pro...After entering into WTO,export volume of agricultural products in China quickly increases,but its proportion in total trade volume becomes lower and lower,and there are more and more trade barriers of agricultural products. In this paper,based on the data during 1994-2016,error correction model is established to test and analyze the relationship between economic growth and export of agricultural products in China. The results show that change of agricultural products export in China has positive impact on GDP in short time,and they also have longterm stable relationship. When they lag for different periods,economic growth and export of agricultural products have unidirectional causality.展开更多
AIM:To investigate the role of connective tissue growth factor(CTGF)and vascular endothelial growth factor(VEGF)in the protein profile of the aqueous humor in patients with proliferative diabetic retinopathy(PDR)follo...AIM:To investigate the role of connective tissue growth factor(CTGF)and vascular endothelial growth factor(VEGF)in the protein profile of the aqueous humor in patients with proliferative diabetic retinopathy(PDR)following intravitreal injection of conbercept.METHODS:This study included 72 PDR patients and 8 cataract patients as controls.PDR patients were divided into 3 groups according to the intervals of 3,5,and 7d between intravitreal conbercept(IVC,0.5 mg/0.05 mL)injection and pars plana vitrectomy(PPV)performed.Aqueous humor samples were collected before and after IVC and PPV for VEGF and CTGF levels detected with enzyme-linked immunosorbent assay(ELISA).The differential proteomics of 10 patients who underwent PPV surgery 5d after IVC and 8 normal controls was studied,Gene Ontology(GO)and Kyoto Encyclopedia of Genes and Genomes(KEGG)analysis were performed on the data,and the protein interaction network of 23 differential proteins was studied.RESULTS:Post-IVC,VEGF levels decreased and CTGF levels increased significantly in aqueous humor,with the CTGF/VEGF ratio rising significantly at all intervals.Liquid chromatography tandem mass spectrometry(LC-MS/MS)identified differentially expressed proteins between preand post-IVC samples.GO and KEGG analyses revealed involvement in immune response,stress response,complement and coagulation cascades,ferroptosis,and PPAR signaling pathways.PPI analysis highlighted key proteins like APOA1,C3,and transferrin(TF).ELISA assay confirmed the differential expression of proteins such as HBA1,SERPINA1,COL1A1,and ACTB,with significant changes in the IVC groups.CONCLUSION:The study demonstrates that IVC effectively reduces VEGF levels while increasing CTGF levels,thereby modifying the CTGF/VEGF ratio,and IVC significantly alters the protein profile in the aqueous humor of patients with PDR.Proteomic analysis reveals that these changes are associated with critical biological pathways and protein interactions involved in immune response,stress response,and cellular metabolism.展开更多
Extensive numerical simulations and scaling analysis are performed to investigate competitive growth between the linear and nonlinear stochastic dynamic growth systems, which belong to the Edwards–Wilkinson(EW) and K...Extensive numerical simulations and scaling analysis are performed to investigate competitive growth between the linear and nonlinear stochastic dynamic growth systems, which belong to the Edwards–Wilkinson(EW) and Kardar–Parisi–Zhang(KPZ) universality classes, respectively. The linear growth systems include the EW equation and the model of random deposition with surface relaxation(RDSR), the nonlinear growth systems involve the KPZ equation and typical discrete models including ballistic deposition(BD), etching, and restricted solid on solid(RSOS). The scaling exponents are obtained in both the(1 + 1)-and(2 + 1)-dimensional competitive growth with the nonlinear growth probability p and the linear proportion 1-p. Our results show that, when p changes from 0 to 1, there exist non-trivial crossover effects from EW to KPZ universality classes based on different competitive growth rules. Furthermore, the growth rate and the porosity are also estimated within various linear and nonlinear growths of cooperation and competition.展开更多
BACKGROUND Acute myeloid leukemia(AML)is a disease in which immature hematopoietic cells accumulate in the bone marrow and continuously expand,inhibiting hematopoiesis.The treatment and prognosis of this disease have ...BACKGROUND Acute myeloid leukemia(AML)is a disease in which immature hematopoietic cells accumulate in the bone marrow and continuously expand,inhibiting hematopoiesis.The treatment and prognosis of this disease have always been unsatisfactory.AIM To investigate the correlation between vascular endothelial growth factor(VEGF)and transforming growth factor-β1(TGFβ1)expression and prognosis in older adults with AML.METHODS This study enrolled 80 patients with AML(AML group),including 36 with complete response(AML-CR),23 with partial response(AML-PR),and 21 with no response(AML-NR).The expression levels of VEGF and TGFβ1 were detected by reverse transcription polymerase chain reaction in bone marrow mononuclear cells isolated from 56 healthy controls.Kaplan-Meier analysis was performed to assess overall survival(OS)and progression-or disease-free survival(DFS).Prognostic risk factors were analyzed using a Cox proportional hazards model.RESULTS The AML group showed a VEGF level of 2.68±0.16.VEGF expression was lower in patients with AML-CR than those with AML-PR or AML-NR(P<0.05).TGFβ1 expression in the AML group was 0.33±0.05.Patients with AML-CR showed a higher TGFβ1 expression than those with AML-PR or AML-NR(P<0.05).VEGF and TGFβ1 expression in patients with AML was significantly correlated with the counts of leukocytes,platelets,hemoglobin,and peripheral blood immature cells(P<0.05);Kaplan-Meier survival analysis revealed that patients with high TGFβ1 expression had better OS and DFS than those with low TGFβ1 expression(P<0.05),whereas patients with low VEGF levels showed better OS and DFS than those with high VEGF levels(P<0.05).VEGF,TGFβ1,and platelet count were identified by the Cox proportional hazards model as independent risk factors for OS(P<0.05),while VEGF,TGFβ1,and white blood cell count were independent risk factors for DFS(P<0.05).CONCLUSION Decreased VEGF expression and increased TGFβ1 expression in patients with AML provide valuable references for determining and individualizing clinical treatment strategies.展开更多
BACKGROUND In recent years,approximately half of the newly diagnosed cases and mortalities attributed to hepatocellular carcinoma(HCC)have been reported in China.Despite the high incidence of HCC,there remains a pauci...BACKGROUND In recent years,approximately half of the newly diagnosed cases and mortalities attributed to hepatocellular carcinoma(HCC)have been reported in China.Despite the high incidence of HCC,there remains a paucity of data regarding the natural growth pattern and the determination of optimal surveillance intervals specific to the Chinese population.AIM To quantify the natural tumor growth pattern of HCC in regional China.METHODS A retrospective analysis was performed on patients from a single institution in Southwest China who had undergone two or more serial dynamic computed tomography or magnetic resonance imaging scans between 2014 and 2020,without having received any anti-cancer therapy.Tumor growth was assessed using tumor volume doubling time(TVDT)and tumor growth rate(TGR),with volumes measured manually by experienced radiologists.Simple univariate linear regression and descriptive analysis were applied to explore associations between growth rates and clinical factors.RESULTS This study identifies the median TVDT for HCC as 163.4 d,interquartile range(IQR)72.1 to 302.3 d,with a daily TGR of 0.42%(IQR 0.206%-0.97%).HCC growth patterns reveal that about one-third of tumors grow indolently with TVDT exceeding 270 d,another one-third of tumors exhibit rapid growth with TVDT under 90 d,and the remaining tumors show intermediate growth rates,with TVDT ranging between 3 to 9 months.CONCLUSION The identified TGRs support biannual surveillance and follow-up for HCC patients in certain regions of China.Given the observed heterogeneity in HCC growth,further investigation is warranted.展开更多
This paper conducts a comprehensive analysis of the export dynamics within the Ukrainian timber industry, emphasizing its pivotal role in the national economy. The study begins by outlining the research objectives, co...This paper conducts a comprehensive analysis of the export dynamics within the Ukrainian timber industry, emphasizing its pivotal role in the national economy. The study begins by outlining the research objectives, context, and innovative methodologies, setting the stage for a deep dive into the theoretical underpinnings of sustainable and competitive trade. It explores Ukraine’s rich forest biodiversity across varied vegetation zones and its geopolitical significance. Detailed evaluations of forest resource management, policy frameworks, and institutional support form the core of the analysis. Challenges such as imbalanced export structures and legal inconsistencies are critically examined. The research employs trade gravity models and competitive indicators like the Revealed Comparative Advantage (RCA) and Market Share (MS) to assess factors influencing exports and to forecast potential growth areas. The findings inform strategic recommendations aimed at enhancing export capacity through market diversification, brand development, and legal stability. The conclusion highlights the need for strategic interventions to harness Ukraine’s timber resources sustainably, balancing economic gains with environmental stewardship.展开更多
文摘2007 has already said farewell to us,however,the influences and meditations it brought are still fresh.In the past year, Chinese textile industry has waved through ups and downs:increasing austerity of external environment and adjustment of internal policies seemingly kept squeezing its profit margin,even the living space. But,to everyone’s gratification, many Chinese textile industries survived from diversity and carved out ways through twists and turns.However,while we were ready to breathe for relief,the snow of 2008 once again triggered people’s worries,and the continuing CPI growth as well as RMB appreciation circumstance,many export-oriented enterprises,like riding a tiger,are tortured by the idea whether do textile business or not, if do,how.Fortunately, some enterprise began to turn their attention to domestic market and pay more efforts to brand building and technology innovation with intends to develop new markets……
文摘China’s swift and substantial economic growth over the past 20 years has made the country one of the top industrial powers in the world, second only the United States. From the perspective of ecology and the impact on the environment produced by economic and industrial growth, the exports that have driven rapid growth have also resulted in an alarming level of environmental pollution in major Chinese cities. Research has shown that the Chinese government’s investment in bringing down pollution levels has been insufficient and ineffective. The monetary amount allocated for pollution reduction has barely reached 0.15% of the country’s GDP and has failed to meaningfully reverse the effects of industrialization, including increased exports and economic growth rates affecting China’s ecology. The present study investigated China’s ecological situation in terms of the industrial production that has generated its level of exports, with special focus on problems related to water, air, and solid waste. An econometric analysis was conducted to determine the relationship between the main variables. The exports and GDP (dependent variable), air pollution, water pollution, and industrial solid waste (independent variables) were provided by the Institute of Statistics and the Environment Institute of China for this study. The data was managed in Econometric Eviews 7.0 software and yielded an adjusted R<sup>2 </sup>of 96.09% (high correlation) with an interesting correlation between the exports and three independent variables;after subsequent variable analysis, we found that investments in water and industrial solid waste were not significant (i.e., that said investments have failed to solve the pollution problem). It is necessary to review the Chinese investment policy with special attention to these variables to appropriately respond to China’s ecological crisis.
文摘The study examined the causal relationship between export and economic growth based on monthly data for the period 2010 to 2019. Composite Index Economic Activity (CIEA) was used as a proxy for real GDP (economic growth). </span><span style="font-family:Verdana;">Time series</span><span style="font-family:Verdana;"> econometric techniques were employed to explore long-run and </span><span style="font-family:Verdana;">short run</span><span style="font-family:Verdana;"> relationships as well as the causality between them.</span><span style="font-family:Verdana;"> </span><span style="font-family:Verdana;">The results revealed the existence of long-run relationships;evidence of bi-directional causality and a rapid adjustment to equilibrium between real GDP and exports. Recommendations </span></span><span style="font-family:Verdana;">are</span><span style="font-family:""> <span style="font-family:Verdana;">that,</span> <span style="font-family:Verdana;">policy makers</span><span style="font-family:Verdana;"> should focus on implementing </span><span style="font-family:Verdana;">export oriented</span><span style="font-family:Verdana;"> policies and promote economic growth to achieve sustainable development.
文摘Imports and exports In the period of January-October,Chinese imports and exports have maintained rapid growth,the structure has continued to be optimized,the transformation of growth drivers has been accelerated,the quality and efficiency have improved,and momentum of steady growth has been further consolidated.
文摘China’s foreign trade in 2015 2015 was a very unusual year in the history of China’s foreign trade,the situation became more complicated,and downward pressure increased significantly.According to Customs figures,China’s total import and export in 2015 reached 24.58 trillion yuan,down 7%year on year(the same below).Export was 14.14 trillion yuan,down 1.8%,and import 10.45 trillion yuan。
文摘Along with the rapid development of its foreign trade, China’s food imports and exports have also increased by a large margin in recent years. In 1994, the total value of imports and exports of food in the country reached US$12.
文摘China will take comprehensive measures next year to ensure a stable textile export growth, the Ministry of Commerce (MOFCOM) said. Since the country ’s textile export faces complex situation amid a world economy slowdown and financial turmoil,
文摘Since reform and opening-up in 1978, changes in China's industrial structure have generally followed the pattern of "Kuznets facts" but still exhibits some unique characteristics, which led us to raise the following three questions regarding China's structural transformation:(1) Why did the share of China's agricultural and manufacturing employment reduce/increase intermittently rather than continuously?(2) Why did the share of China's agricultural employment increase during certain periods? When the share of manufacturing employment reduced, why did the workforce reversely flow into agriculture rather than move to the service sector?(3) Why did growth in the share of China's service sector employment decelerate before reaching its peak? Why did the share of employment in the industrial sector suddenly increase after an abrupt decline? This paper creates a multisector economic growth model that contains non-homothetic preferences and differentiated productivity, and incorporates the "two drivers" therein for a demand-side estimation and analysis. The result shows that China's economic growth model driven by net export and investment is a critical factor for explaining the three questions regarding its structural transformation. This paper believes that only by implementing supply-side structural reforms, reducing the dependence on net export and investment, and achieving sustainable endogenous economic growth will China be able to expedite its industrial restructuring.
文摘The purpose of this review is to communicate the research results of Chinese academia in this field to interested scholars in Western academia.Our review question is:What were the factors that positively or negatively influenced China’s export?We designed a systematic review protocol and then conducted a seven-round in-depth search.After the searching and checking process,a database of 620 academic journal articles was created.Altogether,we find 269 factors have boosted or hindered China’s export.Majority of researches focused on macro level factors.Very few papers studied the firm level or individual level factors.Based on our database,several most frequently studied factors that affect China’s export are identified.In the end,a future research direction is proposed.
文摘China’s foreign trade in November 2014According to Customs figures,China’s total import and export in November last year reached 2.2681trillion yuan,down 0.3%year on year(the same below).Export was 1.3014trillion yuan,up 4.9%,and import0.9666 trillion yuan,down 6.5%.Trade surplus was 334.8 billion yuan,up60.5%.In terms of the U.S.dollar,the total import and export in September2014 reached US$368.85 billion,down 0.5%,among which,export
文摘Yunnan Province is the bridgehead for the opening of the southwest region in China,and the economic frontier of China-ASEAN economic cooperation,where the export of agricultural products plays an important role in promoting the openness of the southwest region and strengthening China-ASEAN economic cooperation.In this paper,we use CMS model to analyze causes of the increase in the exports of agricultural products in Yunnan Province during the period 2001-2010.It is found that the expanded import scale of agricultural products in the world,improvement in the export competitiveness of products and the adaption of product export structure to the changes in the structure of world import demand,are the main factors responsible for increase in the exports of agricultural products in Yunnan Province.In recent years, the improvement of competitiveness of the export of agricultural products becomes a key factor for the growth of the export of agricultural products in Yunnan Province.In terms of the products classified,strong export competitiveness has promoted the export of plant products,such as beverages and tobacco,while weak export competitiveness and unreasonable export structure has impeded the export of animal products,plant and animal oil and fat products.
基金This work was supported by the Special Project of Performance Incentive and Guidance for Scientific Research Institutions of Chongqing,China (jxyn2022-5)。
文摘In recent years,growth hormone and insulin-like growth factors have become key regulators of bone metabolism and remodeling,crucial for maintaining healthy bone mass throughout life.Studies have shown that adult growth hormone deficiency leads to alterations in bone remodeling,significantly affecting bone microarchitecture and increasing fracture risk.Although recombinant human growth hormone replacement therapy can mitigate these adverse effects,improving bone density,and reduce fracture risk,its effectiveness in treating osteoporosis,especially in adults with established growth hormone deficiency,seems limited.Bisphosphonates inhibit bone resorption by targeting farnesyl pyrophosphate synthase in osteoclasts,and clinical trials have confirmed their efficacy in improving osteoporosis.Therefore,for adult growth hormone deficiency patients with osteoporosis,the use of bisphosphonates alongside growth hormone replacement therapy is recommended.
文摘After entering into WTO,export volume of agricultural products in China quickly increases,but its proportion in total trade volume becomes lower and lower,and there are more and more trade barriers of agricultural products. In this paper,based on the data during 1994-2016,error correction model is established to test and analyze the relationship between economic growth and export of agricultural products in China. The results show that change of agricultural products export in China has positive impact on GDP in short time,and they also have longterm stable relationship. When they lag for different periods,economic growth and export of agricultural products have unidirectional causality.
文摘AIM:To investigate the role of connective tissue growth factor(CTGF)and vascular endothelial growth factor(VEGF)in the protein profile of the aqueous humor in patients with proliferative diabetic retinopathy(PDR)following intravitreal injection of conbercept.METHODS:This study included 72 PDR patients and 8 cataract patients as controls.PDR patients were divided into 3 groups according to the intervals of 3,5,and 7d between intravitreal conbercept(IVC,0.5 mg/0.05 mL)injection and pars plana vitrectomy(PPV)performed.Aqueous humor samples were collected before and after IVC and PPV for VEGF and CTGF levels detected with enzyme-linked immunosorbent assay(ELISA).The differential proteomics of 10 patients who underwent PPV surgery 5d after IVC and 8 normal controls was studied,Gene Ontology(GO)and Kyoto Encyclopedia of Genes and Genomes(KEGG)analysis were performed on the data,and the protein interaction network of 23 differential proteins was studied.RESULTS:Post-IVC,VEGF levels decreased and CTGF levels increased significantly in aqueous humor,with the CTGF/VEGF ratio rising significantly at all intervals.Liquid chromatography tandem mass spectrometry(LC-MS/MS)identified differentially expressed proteins between preand post-IVC samples.GO and KEGG analyses revealed involvement in immune response,stress response,complement and coagulation cascades,ferroptosis,and PPAR signaling pathways.PPI analysis highlighted key proteins like APOA1,C3,and transferrin(TF).ELISA assay confirmed the differential expression of proteins such as HBA1,SERPINA1,COL1A1,and ACTB,with significant changes in the IVC groups.CONCLUSION:The study demonstrates that IVC effectively reduces VEGF levels while increasing CTGF levels,thereby modifying the CTGF/VEGF ratio,and IVC significantly alters the protein profile in the aqueous humor of patients with PDR.Proteomic analysis reveals that these changes are associated with critical biological pathways and protein interactions involved in immune response,stress response,and cellular metabolism.
基金supported by Undergraduate Training Program for Innovation and Entrepreneurship of China University of Mining and Technology (CUMT)(Grant No. 202110290059Z)Fundamental Research Funds for the Central Universities of CUMT (Grant No. 2020ZDPYMS33)。
文摘Extensive numerical simulations and scaling analysis are performed to investigate competitive growth between the linear and nonlinear stochastic dynamic growth systems, which belong to the Edwards–Wilkinson(EW) and Kardar–Parisi–Zhang(KPZ) universality classes, respectively. The linear growth systems include the EW equation and the model of random deposition with surface relaxation(RDSR), the nonlinear growth systems involve the KPZ equation and typical discrete models including ballistic deposition(BD), etching, and restricted solid on solid(RSOS). The scaling exponents are obtained in both the(1 + 1)-and(2 + 1)-dimensional competitive growth with the nonlinear growth probability p and the linear proportion 1-p. Our results show that, when p changes from 0 to 1, there exist non-trivial crossover effects from EW to KPZ universality classes based on different competitive growth rules. Furthermore, the growth rate and the porosity are also estimated within various linear and nonlinear growths of cooperation and competition.
基金the Ethic Committee of Suzhou Hospital of Anhui Medical University(Approval No.C2024003).
文摘BACKGROUND Acute myeloid leukemia(AML)is a disease in which immature hematopoietic cells accumulate in the bone marrow and continuously expand,inhibiting hematopoiesis.The treatment and prognosis of this disease have always been unsatisfactory.AIM To investigate the correlation between vascular endothelial growth factor(VEGF)and transforming growth factor-β1(TGFβ1)expression and prognosis in older adults with AML.METHODS This study enrolled 80 patients with AML(AML group),including 36 with complete response(AML-CR),23 with partial response(AML-PR),and 21 with no response(AML-NR).The expression levels of VEGF and TGFβ1 were detected by reverse transcription polymerase chain reaction in bone marrow mononuclear cells isolated from 56 healthy controls.Kaplan-Meier analysis was performed to assess overall survival(OS)and progression-or disease-free survival(DFS).Prognostic risk factors were analyzed using a Cox proportional hazards model.RESULTS The AML group showed a VEGF level of 2.68±0.16.VEGF expression was lower in patients with AML-CR than those with AML-PR or AML-NR(P<0.05).TGFβ1 expression in the AML group was 0.33±0.05.Patients with AML-CR showed a higher TGFβ1 expression than those with AML-PR or AML-NR(P<0.05).VEGF and TGFβ1 expression in patients with AML was significantly correlated with the counts of leukocytes,platelets,hemoglobin,and peripheral blood immature cells(P<0.05);Kaplan-Meier survival analysis revealed that patients with high TGFβ1 expression had better OS and DFS than those with low TGFβ1 expression(P<0.05),whereas patients with low VEGF levels showed better OS and DFS than those with high VEGF levels(P<0.05).VEGF,TGFβ1,and platelet count were identified by the Cox proportional hazards model as independent risk factors for OS(P<0.05),while VEGF,TGFβ1,and white blood cell count were independent risk factors for DFS(P<0.05).CONCLUSION Decreased VEGF expression and increased TGFβ1 expression in patients with AML provide valuable references for determining and individualizing clinical treatment strategies.
基金Supported by Cultivate Project for the National Natural Science Foundation of China,No.gyfynsfc[2020]-27and National Natural Science Foundation of China,No.81960328.
文摘BACKGROUND In recent years,approximately half of the newly diagnosed cases and mortalities attributed to hepatocellular carcinoma(HCC)have been reported in China.Despite the high incidence of HCC,there remains a paucity of data regarding the natural growth pattern and the determination of optimal surveillance intervals specific to the Chinese population.AIM To quantify the natural tumor growth pattern of HCC in regional China.METHODS A retrospective analysis was performed on patients from a single institution in Southwest China who had undergone two or more serial dynamic computed tomography or magnetic resonance imaging scans between 2014 and 2020,without having received any anti-cancer therapy.Tumor growth was assessed using tumor volume doubling time(TVDT)and tumor growth rate(TGR),with volumes measured manually by experienced radiologists.Simple univariate linear regression and descriptive analysis were applied to explore associations between growth rates and clinical factors.RESULTS This study identifies the median TVDT for HCC as 163.4 d,interquartile range(IQR)72.1 to 302.3 d,with a daily TGR of 0.42%(IQR 0.206%-0.97%).HCC growth patterns reveal that about one-third of tumors grow indolently with TVDT exceeding 270 d,another one-third of tumors exhibit rapid growth with TVDT under 90 d,and the remaining tumors show intermediate growth rates,with TVDT ranging between 3 to 9 months.CONCLUSION The identified TGRs support biannual surveillance and follow-up for HCC patients in certain regions of China.Given the observed heterogeneity in HCC growth,further investigation is warranted.
文摘This paper conducts a comprehensive analysis of the export dynamics within the Ukrainian timber industry, emphasizing its pivotal role in the national economy. The study begins by outlining the research objectives, context, and innovative methodologies, setting the stage for a deep dive into the theoretical underpinnings of sustainable and competitive trade. It explores Ukraine’s rich forest biodiversity across varied vegetation zones and its geopolitical significance. Detailed evaluations of forest resource management, policy frameworks, and institutional support form the core of the analysis. Challenges such as imbalanced export structures and legal inconsistencies are critically examined. The research employs trade gravity models and competitive indicators like the Revealed Comparative Advantage (RCA) and Market Share (MS) to assess factors influencing exports and to forecast potential growth areas. The findings inform strategic recommendations aimed at enhancing export capacity through market diversification, brand development, and legal stability. The conclusion highlights the need for strategic interventions to harness Ukraine’s timber resources sustainably, balancing economic gains with environmental stewardship.