The objective of style transfer is to maintain the content of an image while transferring the style of another image.However,conventional methods face challenges in preserving facial features,especially in Korean port...The objective of style transfer is to maintain the content of an image while transferring the style of another image.However,conventional methods face challenges in preserving facial features,especially in Korean portraits where elements like the“Gat”(a traditional Korean hat)are prevalent.This paper proposes a deep learning network designed to perform style transfer that includes the“Gat”while preserving the identity of the face.Unlike traditional style transfer techniques,the proposed method aims to preserve the texture,attire,and the“Gat”in the style image by employing image sharpening and face landmark,with the GAN.The color,texture,and intensity were extracted differently based on the characteristics of each block and layer of the pre-trained VGG-16,and only the necessary elements during training were preserved using a facial landmark mask.The head area was presented using the eyebrow area to transfer the“Gat”.Furthermore,the identity of the face was retained,and style correlation was considered based on the Gram matrix.To evaluate performance,we introduced a metric using PSNR and SSIM,with an emphasis on median values through new weightings for style transfer in Korean portraits.Additionally,we have conducted a survey that evaluated the content,style,and naturalness of the transferred results,and based on the assessment,we can confidently conclude that our method to maintain the integrity of content surpasses the previous research.Our approach,enriched by landmarks preservation and diverse loss functions,including those related to“Gat”,outperformed previous researches in facial identity preservation.展开更多
Predicting disruptions across different tokamaks is necessary for next generation device.Future large-scale tokamaks can hardly tolerate disruptions at high performance discharge,which makes it difficult for current d...Predicting disruptions across different tokamaks is necessary for next generation device.Future large-scale tokamaks can hardly tolerate disruptions at high performance discharge,which makes it difficult for current data-driven methods to obtain an acceptable result.A machine learning method capable of transferring a disruption prediction model trained on one tokamak to another is required to solve the problem.The key is a feature extractor which is able to extract common disruption precursor traces in tokamak diagnostic data,and can be easily transferred to other tokamaks.Based on the concerns above,this paper presents a deep feature extractor,namely,the fusion feature extractor(FFE),which is designed specifically for extracting disruption precursor features from common diagnostics on tokamaks.Furthermore,an FFE-based disruption predictor on J-TEXT is demonstrated.The feature extractor is aimed to extracting disruption-related precursors and is designed according to the precursors of disruption and their representations in common tokamak diagnostics.Strong inductive bias on tokamak diagnostics data is introduced.The paper presents the evolution of the neural network feature extractor and its comparison against general deep neural networks,as well as a physics-based feature extraction with a traditional machine learning method.Results demonstrate that the FFE may reach a similar effect with physics-guided manual feature extraction,and obtain a better result compared with other deep learning methods.展开更多
Afuzzy extractor can extract an almost uniformrandom string from a noisy source with enough entropy such as biometric data.To reproduce an identical key from repeated readings of biometric data,the fuzzy extractor gen...Afuzzy extractor can extract an almost uniformrandom string from a noisy source with enough entropy such as biometric data.To reproduce an identical key from repeated readings of biometric data,the fuzzy extractor generates a helper data and a random string from biometric data and uses the helper data to reproduce the random string from the second reading.In 2013,Fuller et al.proposed a computational fuzzy extractor based on the learning with errors problem.Their construction,however,can tolerate a sub-linear fraction of errors and has an inefficient decoding algorithm,which causes the reproducing time to increase significantly.In 2016,Canetti et al.proposed a fuzzy extractor with inputs from low-entropy distributions based on a strong primitive,which is called digital locker.However,their construction necessitates an excessive amount of storage space for the helper data,which is stored in authentication server.Based on these observations,we propose a new efficient computational fuzzy extractorwith small size of helper data.Our scheme supports reusability and robustness,which are security notions that must be satisfied in order to use a fuzzy extractor as a secure authentication method in real life.Also,it conceals no information about the biometric data and thanks to the new decoding algorithm can tolerate linear errors.Based on the non-uniform learning with errors problem,we present a formal security proof for the proposed fuzzy extractor.Furthermore,we analyze the performance of our fuzzy extractor scheme and provide parameter sets that meet the security requirements.As a result of our implementation and analysis,we show that our scheme outperforms previous fuzzy extractor schemes in terms of the efficiency of the generation and reproduction algorithms,as well as the size of helper data.展开更多
Solvent extraction phenol from coal tar were carried out with novel composite YH-3 as extraction agent, and the high flux centrifugal extractor was used as extraction device. Under the premise of high phenol extractio...Solvent extraction phenol from coal tar were carried out with novel composite YH-3 as extraction agent, and the high flux centrifugal extractor was used as extraction device. Under the premise of high phenol extraction rate, composite YH-3 extraction agent reduces n-n interaction between phenolic compounds and aromatic hydrocarbons, thus decreasing the entrainment of neutral oil. The optimization of operation conditions, such as the diameter of heavy phase weir HWD, the flow ratio, the total flow rate and the rotation speed, are necessary. For single stage extraction experiment, the mass transfer efficiency was up to 84% while the rate of extraction agent loss was lower than 0.28% with the operation conditions of 29 mm of the heavy phase weir diameter (HWD), 1:1-1.4:1 of the flow ratio range, 160-200 mL/min of the total flow rate and the rotation speed varied from 2200 to 2600 r/min. For three stage counter-current test, the mass transfer efficiency reached up to 92.6% with the optimum operation condition of 29 mm of the HWD, 1:1 of the flow ratio, 200 rnL/min of the total flow rate and 2400 r/rain of the rotation speed. The results indicated that phenol could be extracted effectively from coal tar in the process of multistage continuous count current centrifugal extraction.展开更多
Annular centrifugal extractors(ACEs) offer advantages including excellent hydraulic and mass-transfer performance, small hold-up volume, short residence time,and thus low solvent degradation, high nuclear criticality,...Annular centrifugal extractors(ACEs) offer advantages including excellent hydraulic and mass-transfer performance, small hold-up volume, short residence time,and thus low solvent degradation, high nuclear criticality,easy start-up and shut-down, high compact structure.Therefore, ACEs have attracted increasing interest for future nuclear processing schemes, including the partitioning of high-level liquid waste(HLLW). Laboratoryscale and pilot-scale ACEs have been applied in demonstration tests of the trialkyl phosphine oxide(TRPO) process for HLLW partitioning. In this study, an industrialscale ACE(260 mm in rotor diameter) with magnetic coupling and a ‘‘hanging'' rotor structure was developed for the TRPO process. Moreover, a series of hydraulic and mass-transfer tests were carried out in the industrial-scale ACE. The maximum throughput can reach 10 m^3/h under suitable operation parameters when kerosene is used as the organic phase, and water is used as the aqueous phase. The influence of the total flowrate, the flow ratio(aqueous/organic, A/O), and the rotor speed on the liquid hold-up volume was determined. The extraction stage efficiency is higher than 98% under test parameters for extraction of Nd^(3+) and HNO_3, using 30% TRPO kerosene as theextractant from an HNO_3 solution containing Nd. All results show good performance of the industrial-scale ACE for the TRPO process.展开更多
In this work,a novel rotating microchannel extractor(RME)is designed and further used for the extraction of chromium(Ⅲ)from water.Unexpectedly,the micro-extraction had the same effect as carrying out 2.9-stage cross-...In this work,a novel rotating microchannel extractor(RME)is designed and further used for the extraction of chromium(Ⅲ)from water.Unexpectedly,the micro-extraction had the same effect as carrying out 2.9-stage cross-flow extractions.Various factors,including the gas intake methods,gas intake quantity(Qg),distance between inner rotor and outer wall(D),rotational inner rotor speed(R)and volumetric flow rate(Qa,Qo),were selected to investigate their effect on the extraction efficiency(η)thoroughly.The relation map ofηwith Weaand We(o-g)for RME provides a comprehension for the gas–liquid–liquid extraction process in this RME system.展开更多
In this study,extraction of p-cresol from the simulated wastewater has been studied using centrifugal extractors and QH-1 extractant.The distribution ratio of p-cresol was approximately 308.5 in the QH-1-p-cresol(pH=2...In this study,extraction of p-cresol from the simulated wastewater has been studied using centrifugal extractors and QH-1 extractant.The distribution ratio of p-cresol was approximately 308.5 in the QH-1-p-cresol(pH=2.0)system.The extraction stage efficiency of the single-stage centrifugal extractor was higher than 92%,and the extraction rate of the three-stage cascade was higher than 99%.When 15% NaOH was used for the stripping of p-cresol in QH-1 solution,the stripping rate of the three-stage cascade reached 100%.A mathematical model of multistage countercurrent extraction process that considers the phase volume change,extraction stage efficiency,and phase entrainment was used to simulate the extraction of p-cresol using centrifugal extractors.The calculated results using this model were in good agreement with the experimental results.展开更多
Extraction kinetics of phenol with N,N-di(1-methyl-heptyl) acetamide-kerosene using hollow fiber membrane extractor has been studied. The rate regularities and kinetic types of forward and backward extraction were obt...Extraction kinetics of phenol with N,N-di(1-methyl-heptyl) acetamide-kerosene using hollow fiber membrane extractor has been studied. The rate regularities and kinetic types of forward and backward extraction were obtained respectively by determining the forward and backward extraction rate under various experimental conditions. The mass transfer mechanism was discussed. Both the forward and backward extraction of phenol might be controlled by diffusion processes, and the diffusion resistance for both forward and backward extraction mainly exists in aqueous phase. In addition, ways to optimize the extraction process of phenol were discussed as well.展开更多
The mature design of wireless mobile sensor network makes it to be used in vast verities of applications including from home used to the security surveillance.All such types of applications based on wireless mobile se...The mature design of wireless mobile sensor network makes it to be used in vast verities of applications including from home used to the security surveillance.All such types of applications based on wireless mobile sensor network are generally using real time data,most of them are interested in real time communication directly from cluster head of cluster instead of a base station in cluster network.This would be possible if an external user allows to directly access real time data from the cluster head in cluster wireless mobile sensor network instead of accessing data from base station.But this leads to a serious security breach and degrades the performance of any security protocol available in this domain.Most existing schemes for authentication and cluster key management for external users,exchange a number of messages between cluster head and base station to allow external to access real time data from the base station instead of cluster head.This increase communication cost and delay in such real time access information.To handle this critical issue in cluster wireless mobile sensor network,we propose a lightweight authentication and key management scheme using a fuzzy extractor.In this scheme,any external user can access data directly from the cluster head of any cluster without the involvement of the base station.The proposed scheme only uses the one-way hash functions and bitwise XOR operations,apart from the fuzzy extractor method for the user biometric verification at the login phase.The presented scheme supports scalability for an increasing number of nodes using polynomials.The proposed scheme increases the life-time of the network by decreasing the key pool size.展开更多
There are settings where encryption must be performed by a sender under a time constraint. This paper de-scribes an encryption/decryption algorithm based on modular arithmetic of complex integers called Gaus-sians. It...There are settings where encryption must be performed by a sender under a time constraint. This paper de-scribes an encryption/decryption algorithm based on modular arithmetic of complex integers called Gaus-sians. It is shown how cubic extractors operate and how to find all cubic roots of the Gaussian. All validations (proofs) are provided in the Appendix. Detailed numeric illustrations explain how to use the method of digital isotopes to avoid ambiguity in recovery of the original plaintext by the receiver.展开更多
Natural ventilation is an efficient design strategy for the passive cooling of buildings, especially in tropical countries such as Brazil. Among the ventilation strategies, sheds can be highlighted. These structures c...Natural ventilation is an efficient design strategy for the passive cooling of buildings, especially in tropical countries such as Brazil. Among the ventilation strategies, sheds can be highlighted. These structures consist of roof openings that work as air captors or extractors depending on their location in relation to the prevailing wind directions. The hospitals of the Sarah Network, designed by the Brazilian architect Joao Filgueiras Lima, Lele, are worldwide known for using these elements to improve natural ventilation. This paper analyses the natural ventilation performance of sheds for air collecting and extracting in two Sarah hospitals located in the cities of Salvador and Rio de Janeiro. In each building, the sheds were analyzed for air extracting and collecting. The analyses were carried out by reduced physical models in an atmospheric boundary layer wind tunnel. The wind velocity was measured at external and internal points of the buildings, using hot-wire anemometers. The results show that the wards in Rio de Janeiro hospital are 17% more ventilated than the ones in the Salvador hospital. However, this difference occurs not only because of the collecting sheds but also because of set of openings and the configuration of the covering in hospitals in Rio de Janeiro.展开更多
Continuous manufacturing is considered as one of the future trends of pharmaceutical engineering. In this work, continuous liquid-liquid extraction for sinomenine purification was realized with the usage of centrifuga...Continuous manufacturing is considered as one of the future trends of pharmaceutical engineering. In this work, continuous liquid-liquid extraction for sinomenine purification was realized with the usage of centrifugal extractors. Chloroform was used as the extractant because of the high distribution coefficient (>100). Higher extraction ratio can be obtained when using the centrifugal extractor of Model CWL50-N. The extraction ratio of the second-stage extraction was higher than that of the first-stage extraction. The extraction ratio of the second-stage countercurrent extraction was higher than that of second-stage cross-flow extraction. When chloroform phase was recycled for liquid-liquid extraction, the extraction ratio was also higher than 95%. This work can also be an example of continuous liquid-liquid extraction for the separation of other Chinese medicine components.展开更多
基金supported by Metaverse Lab Program funded by the Ministry of Science and ICT(MSIT),and the Korea Radio Promotion Association(RAPA).
文摘The objective of style transfer is to maintain the content of an image while transferring the style of another image.However,conventional methods face challenges in preserving facial features,especially in Korean portraits where elements like the“Gat”(a traditional Korean hat)are prevalent.This paper proposes a deep learning network designed to perform style transfer that includes the“Gat”while preserving the identity of the face.Unlike traditional style transfer techniques,the proposed method aims to preserve the texture,attire,and the“Gat”in the style image by employing image sharpening and face landmark,with the GAN.The color,texture,and intensity were extracted differently based on the characteristics of each block and layer of the pre-trained VGG-16,and only the necessary elements during training were preserved using a facial landmark mask.The head area was presented using the eyebrow area to transfer the“Gat”.Furthermore,the identity of the face was retained,and style correlation was considered based on the Gram matrix.To evaluate performance,we introduced a metric using PSNR and SSIM,with an emphasis on median values through new weightings for style transfer in Korean portraits.Additionally,we have conducted a survey that evaluated the content,style,and naturalness of the transferred results,and based on the assessment,we can confidently conclude that our method to maintain the integrity of content surpasses the previous research.Our approach,enriched by landmarks preservation and diverse loss functions,including those related to“Gat”,outperformed previous researches in facial identity preservation.
基金Project supported by the National Key R&D Program of China (Grant No. 2022YFE03040004)the National Natural Science Foundation of China (Grant No. 51821005)
文摘Predicting disruptions across different tokamaks is necessary for next generation device.Future large-scale tokamaks can hardly tolerate disruptions at high performance discharge,which makes it difficult for current data-driven methods to obtain an acceptable result.A machine learning method capable of transferring a disruption prediction model trained on one tokamak to another is required to solve the problem.The key is a feature extractor which is able to extract common disruption precursor traces in tokamak diagnostic data,and can be easily transferred to other tokamaks.Based on the concerns above,this paper presents a deep feature extractor,namely,the fusion feature extractor(FFE),which is designed specifically for extracting disruption precursor features from common diagnostics on tokamaks.Furthermore,an FFE-based disruption predictor on J-TEXT is demonstrated.The feature extractor is aimed to extracting disruption-related precursors and is designed according to the precursors of disruption and their representations in common tokamak diagnostics.Strong inductive bias on tokamak diagnostics data is introduced.The paper presents the evolution of the neural network feature extractor and its comparison against general deep neural networks,as well as a physics-based feature extraction with a traditional machine learning method.Results demonstrate that the FFE may reach a similar effect with physics-guided manual feature extraction,and obtain a better result compared with other deep learning methods.
基金supported by Institute of Information&communications Technology Planning&Evaluation(IITP)grant funded by the Korea government(MSIT)(No.2022-0-00518,Blockchain privacy preserving techniques based on data encryption).
文摘Afuzzy extractor can extract an almost uniformrandom string from a noisy source with enough entropy such as biometric data.To reproduce an identical key from repeated readings of biometric data,the fuzzy extractor generates a helper data and a random string from biometric data and uses the helper data to reproduce the random string from the second reading.In 2013,Fuller et al.proposed a computational fuzzy extractor based on the learning with errors problem.Their construction,however,can tolerate a sub-linear fraction of errors and has an inefficient decoding algorithm,which causes the reproducing time to increase significantly.In 2016,Canetti et al.proposed a fuzzy extractor with inputs from low-entropy distributions based on a strong primitive,which is called digital locker.However,their construction necessitates an excessive amount of storage space for the helper data,which is stored in authentication server.Based on these observations,we propose a new efficient computational fuzzy extractorwith small size of helper data.Our scheme supports reusability and robustness,which are security notions that must be satisfied in order to use a fuzzy extractor as a secure authentication method in real life.Also,it conceals no information about the biometric data and thanks to the new decoding algorithm can tolerate linear errors.Based on the non-uniform learning with errors problem,we present a formal security proof for the proposed fuzzy extractor.Furthermore,we analyze the performance of our fuzzy extractor scheme and provide parameter sets that meet the security requirements.As a result of our implementation and analysis,we show that our scheme outperforms previous fuzzy extractor schemes in terms of the efficiency of the generation and reproduction algorithms,as well as the size of helper data.
文摘Solvent extraction phenol from coal tar were carried out with novel composite YH-3 as extraction agent, and the high flux centrifugal extractor was used as extraction device. Under the premise of high phenol extraction rate, composite YH-3 extraction agent reduces n-n interaction between phenolic compounds and aromatic hydrocarbons, thus decreasing the entrainment of neutral oil. The optimization of operation conditions, such as the diameter of heavy phase weir HWD, the flow ratio, the total flow rate and the rotation speed, are necessary. For single stage extraction experiment, the mass transfer efficiency was up to 84% while the rate of extraction agent loss was lower than 0.28% with the operation conditions of 29 mm of the heavy phase weir diameter (HWD), 1:1-1.4:1 of the flow ratio range, 160-200 mL/min of the total flow rate and the rotation speed varied from 2200 to 2600 r/min. For three stage counter-current test, the mass transfer efficiency reached up to 92.6% with the optimum operation condition of 29 mm of the HWD, 1:1 of the flow ratio, 200 rnL/min of the total flow rate and 2400 r/rain of the rotation speed. The results indicated that phenol could be extracted effectively from coal tar in the process of multistage continuous count current centrifugal extraction.
基金supported by the Program for Changjiang Scholars and Innovative Research Team in University(No.IRT13026)the National 863 Program for the Nuclear Fuel Cycling and Nuclear Safety Technology Project(No.2009AA050703)
文摘Annular centrifugal extractors(ACEs) offer advantages including excellent hydraulic and mass-transfer performance, small hold-up volume, short residence time,and thus low solvent degradation, high nuclear criticality,easy start-up and shut-down, high compact structure.Therefore, ACEs have attracted increasing interest for future nuclear processing schemes, including the partitioning of high-level liquid waste(HLLW). Laboratoryscale and pilot-scale ACEs have been applied in demonstration tests of the trialkyl phosphine oxide(TRPO) process for HLLW partitioning. In this study, an industrialscale ACE(260 mm in rotor diameter) with magnetic coupling and a ‘‘hanging'' rotor structure was developed for the TRPO process. Moreover, a series of hydraulic and mass-transfer tests were carried out in the industrial-scale ACE. The maximum throughput can reach 10 m^3/h under suitable operation parameters when kerosene is used as the organic phase, and water is used as the aqueous phase. The influence of the total flowrate, the flow ratio(aqueous/organic, A/O), and the rotor speed on the liquid hold-up volume was determined. The extraction stage efficiency is higher than 98% under test parameters for extraction of Nd^(3+) and HNO_3, using 30% TRPO kerosene as theextractant from an HNO_3 solution containing Nd. All results show good performance of the industrial-scale ACE for the TRPO process.
基金financial support from the National Natural Science Foundation of China(21776181)Sichuan University innovation spark project(2018SCUH0012)+1 种基金Chinese National Key Research and Development Plan(2018YFC1900203-03)Special Project of Building World-class Universities(2030704401004)。
文摘In this work,a novel rotating microchannel extractor(RME)is designed and further used for the extraction of chromium(Ⅲ)from water.Unexpectedly,the micro-extraction had the same effect as carrying out 2.9-stage cross-flow extractions.Various factors,including the gas intake methods,gas intake quantity(Qg),distance between inner rotor and outer wall(D),rotational inner rotor speed(R)and volumetric flow rate(Qa,Qo),were selected to investigate their effect on the extraction efficiency(η)thoroughly.The relation map ofηwith Weaand We(o-g)for RME provides a comprehension for the gas–liquid–liquid extraction process in this RME system.
文摘In this study,extraction of p-cresol from the simulated wastewater has been studied using centrifugal extractors and QH-1 extractant.The distribution ratio of p-cresol was approximately 308.5 in the QH-1-p-cresol(pH=2.0)system.The extraction stage efficiency of the single-stage centrifugal extractor was higher than 92%,and the extraction rate of the three-stage cascade was higher than 99%.When 15% NaOH was used for the stripping of p-cresol in QH-1 solution,the stripping rate of the three-stage cascade reached 100%.A mathematical model of multistage countercurrent extraction process that considers the phase volume change,extraction stage efficiency,and phase entrainment was used to simulate the extraction of p-cresol using centrifugal extractors.The calculated results using this model were in good agreement with the experimental results.
文摘Extraction kinetics of phenol with N,N-di(1-methyl-heptyl) acetamide-kerosene using hollow fiber membrane extractor has been studied. The rate regularities and kinetic types of forward and backward extraction were obtained respectively by determining the forward and backward extraction rate under various experimental conditions. The mass transfer mechanism was discussed. Both the forward and backward extraction of phenol might be controlled by diffusion processes, and the diffusion resistance for both forward and backward extraction mainly exists in aqueous phase. In addition, ways to optimize the extraction process of phenol were discussed as well.
基金This research was financially supported in part by the Ministry of Trade,Industry and Energy(MOTIE)and Korea Institute for Advancement of Technology(KIAT)through the International Cooperative R&D program.(Project No.P0016038)in part by the MSIT(Ministry of Science and ICT),Korea,under the ITRC(Information Technology Research Center)support program(IITP-2021-2016-0-00312)supervised by the IITP(Institute for Information&communications Technology Planning&Evaluation).
文摘The mature design of wireless mobile sensor network makes it to be used in vast verities of applications including from home used to the security surveillance.All such types of applications based on wireless mobile sensor network are generally using real time data,most of them are interested in real time communication directly from cluster head of cluster instead of a base station in cluster network.This would be possible if an external user allows to directly access real time data from the cluster head in cluster wireless mobile sensor network instead of accessing data from base station.But this leads to a serious security breach and degrades the performance of any security protocol available in this domain.Most existing schemes for authentication and cluster key management for external users,exchange a number of messages between cluster head and base station to allow external to access real time data from the base station instead of cluster head.This increase communication cost and delay in such real time access information.To handle this critical issue in cluster wireless mobile sensor network,we propose a lightweight authentication and key management scheme using a fuzzy extractor.In this scheme,any external user can access data directly from the cluster head of any cluster without the involvement of the base station.The proposed scheme only uses the one-way hash functions and bitwise XOR operations,apart from the fuzzy extractor method for the user biometric verification at the login phase.The presented scheme supports scalability for an increasing number of nodes using polynomials.The proposed scheme increases the life-time of the network by decreasing the key pool size.
文摘There are settings where encryption must be performed by a sender under a time constraint. This paper de-scribes an encryption/decryption algorithm based on modular arithmetic of complex integers called Gaus-sians. It is shown how cubic extractors operate and how to find all cubic roots of the Gaussian. All validations (proofs) are provided in the Appendix. Detailed numeric illustrations explain how to use the method of digital isotopes to avoid ambiguity in recovery of the original plaintext by the receiver.
文摘Natural ventilation is an efficient design strategy for the passive cooling of buildings, especially in tropical countries such as Brazil. Among the ventilation strategies, sheds can be highlighted. These structures consist of roof openings that work as air captors or extractors depending on their location in relation to the prevailing wind directions. The hospitals of the Sarah Network, designed by the Brazilian architect Joao Filgueiras Lima, Lele, are worldwide known for using these elements to improve natural ventilation. This paper analyses the natural ventilation performance of sheds for air collecting and extracting in two Sarah hospitals located in the cities of Salvador and Rio de Janeiro. In each building, the sheds were analyzed for air extracting and collecting. The analyses were carried out by reduced physical models in an atmospheric boundary layer wind tunnel. The wind velocity was measured at external and internal points of the buildings, using hot-wire anemometers. The results show that the wards in Rio de Janeiro hospital are 17% more ventilated than the ones in the Salvador hospital. However, this difference occurs not only because of the collecting sheds but also because of set of openings and the configuration of the covering in hospitals in Rio de Janeiro.
文摘Continuous manufacturing is considered as one of the future trends of pharmaceutical engineering. In this work, continuous liquid-liquid extraction for sinomenine purification was realized with the usage of centrifugal extractors. Chloroform was used as the extractant because of the high distribution coefficient (>100). Higher extraction ratio can be obtained when using the centrifugal extractor of Model CWL50-N. The extraction ratio of the second-stage extraction was higher than that of the first-stage extraction. The extraction ratio of the second-stage countercurrent extraction was higher than that of second-stage cross-flow extraction. When chloroform phase was recycled for liquid-liquid extraction, the extraction ratio was also higher than 95%. This work can also be an example of continuous liquid-liquid extraction for the separation of other Chinese medicine components.