OML:an online multi-particle locating method for high-resolution single-event effects studies

Identifying sensitive areas in integrated circuits susceptible to single-event effects(SEE)is crucial for improving radiation hardness.This study presents an online multi-track location(OML)framework to enhance the high-resolution online trajectory detection for the Hi’Beam-SEE system,which aims to localize SEE-sensitive positions on the IC at the micrometer scale and in real time.We employed a reparameterization method to accelerate the inference speed,merging the branches of the backbone of the location in the deployment scenario.Additionally,we designed an irregular convolution kernel,an attention mechanism,and a fused loss function to improve the positioning accuracy.OML demonstrates exceptional realtime processing capabilities,achieving a positioning accuracy of 1.83μm in processing data generated by the Hi’Beam-SEE system at 163 frames per second per GPU.

Evaluation of Training Course Effects on Integrated Sexual and Reproductive Health Counseling

Objective To evaluate the training course effects on integrated sexual and reproductive health （SRH） counseling, so as to improve family planning providers＇ capacities of SRH counseling. Methods The SRH training course was conducted by using new curriculum and participatory training methods. The purpose was meeting the SRH needs of clients. Evaluations were done by pre- and post-training questionnaires to trainees. Results The average total scores of trainees were 54.9 before trained and 83.4 after trained respectively. As to trainees＇ self evaluation of the capacities, the capacity for comfortably discussing sexuality and related issues with clients increased from 9.9% to 90.7%, the capacity for helping clients to understand their sexual risk factors increased from 12.5% to 92.2%, the capacity for helping clients assessing their own needs for SRH services, information and emotional support increased from 16.0% to 87.8%, and the capacity for helping clients to develop negotiation and communication skills increased from 12.0% to 86. 0%. Conclusion The training course of integrated SRH counseling changed the traditional training types and services concept o f family planning service providers, and the trainees＇ capacities of implementing integrated SRH counseling also improved very much.

Poverty reduction effects of integrating high-quality development and cultural tourism in China

The integration of the cultural tourism industry with high-quality development is believed to be an important method of alleviating poverty.Most research in this area has focused on single towns,cities,or regions without considering the spillover effects of neighboring areas.To fill this gap,this study applies a spatial panel econometric model to empirically test the spatial spillover effects of integrating the cultural tourism industry with high-quality developments and their mechanisms of poverty alleviation based on provincial panel data of the Chinese Mainland from 2010 to 2020.Four key results are presented.First,there is an obvious spatial dependence on the high-quality development scale,specialization level,and poverty level of cultural tourism integration.The common panel model is found to overestimate the impact of this integration on poverty alleviation because it ignores the spatial spillover-related explanatory variables.Second,the scale of development quality is found to have no significant impact on poverty alleviation when integrating cultural tourism;however,the level of development specialization has both a direct impact on poverty alleviation and the spatial spillover effect.Third,the integration of the cultural tourism industry in the Central and Western regions is shown to have a strong direct effect on poverty reduction through high-quality development.However,the spillover effect on poverty reduction in the Eastern region is greater than that in the Central and Western regions.Fourth,the integration of high-quality development and cultural tourism is found to have a direct impact on poverty alleviation overall by promoting tourism consumption,material capital accumulation,and structural transformation.

Path Integral Formulation for Ionic Broadening in Plasmas: Lyman-<i>α</i>with Fine Structure and Dynamical Effects

Using the path integral formalism, the fine structure and dynamics effects are taken into account for the broadening of spectral lines in a plasma. A compact expression of the dipolar autocorrelation function for an emitter in the plasma is derived for Lyman alpha lines with fine structure. The expression of the dipolar autocorrelation function takes into account the dynamics effects, which are represented by the time microfield autocorrelation function.

Effects of Integrated Technology of Medicine and Fertilizer on Bacterial Wilt of Tobacco

In order to validate the control effects of integrated technology of medicine and fertilizer on tobacco bacterial wilt,field experiments were conducted by using youmeili and tetracycline as the test agents.The results obtained were listed as follows:(1)The incidence rate of bacterial wilt ascended more quickly after July 10 th,the incidence of CK reached 78.30%on July 25 th.(2)The control effect of“youmeili 3 g+tetramycin 200 times liquid”reached 69.47%,significantly higher than other treatments.(3)The output value of“Youmeil 3 g+tetramycin 200 times liquid”served as 1635.66 yuan/667m^2,with the highest economic character in all treatments.In a word,integrated technology of medicine and fertilizer was a feasible approach to control tobacco bacterial wilt.

Integrating Downstream Ecological, Social and Economic Effects of Hydropower to Hydraulic Modeling: A Review

Hydropower gains increasing importance as a steerable and controllable power source in a renewable energy mix and deregulated markets. Although hydropower produces fossil-free energy, it has a significant impact on the local environment. This review investigates the effects of flow alterations by hydropower on the downstream river system and the possibilities to integrate these effects into hydraulic modeling. The results show that various effects of flow regulation on the ecosystem, but also social and economic effects on related communities were observed in the last decades. The application of hydraulic models for investigations of ecological effects is common. Especially hydraulic effects and effects on fish were extensively modeled with the help of hydraulic 1D- and 2D-simulations. Current applications to investigate social and economic effects integrated into hydraulic modeling are meanwhile limited. Approaches to realizing this integration are presented. Further research on the economic valuation of ecosystems and integration of social and economic effects to hydraulic models is necessary to develop holistic tools to support decision-making on sustainable hydropower.

Activities of Urease and Phosphatase in Integrated Vertical Flow Constructed Wetland and Purification Effect of Black and Malodorous River

[Objective]The activities of urease and phosphatase in integrated vertical flow constructed wetland and purification effect of black and malodorous river were studied.[Method]Honeycomb stone and soft filler were used as matrix,the biological grid integrated vertical flow constructed wetland system was built to strengthen treatment for black and malodorous river,and the activities of urease and phosphatase of two fillers in different functional areas of constructed wetland were tested to study the film formation property of two fillers in different functional areas.[Result]Both urease and phosphatase activities on biofilm of soft filler were significantly higher than on biofilm of honeycomb stone filler;indicating that choosing soft filler was more advantageous to the growth of biofilm;and urease activity had significant correlation with total nitrogen removal rate,while phosphatase activity had no significant correlation with total phosphorus removal rate.[Conclusion]This study provided evidences for utilizing the activities of urease and phosphatase to evaluate the purification effect of black and malodorous river and choose appropriate filler.

INTEGRATION OF HUMAN FACTORS ENGINEERING AND QUALITY MANAGEMENT

Human factors engineering and quality management are different research branches in the field of industrial engineering.A basis for interaction based on the concepts and techniques of human factors engineering and quality management with some practical examples of cooperative effect is defined in this paper.The specific challenges about the quality management in manufacturing and service are presented to demonstrate that the human factors analysis of quality problems leads to new tends for integrated development.

Integration system research and development for three-dimensional laser scanning information visualization in goaf

An integration processing system of three-dimensional laser scanning information visualization in goaf was developed. It is provided with multiple functions, such as laser scanning information management for goaf, cloud data de-noising optimization, construction, display and operation of three-dimensional model, model editing, profile generation, calculation of goaf volume and roof area, Boolean calculation among models and interaction with the third party soft ware. Concerning this system with a concise interface, plentiful data input/output interfaces, it is featured with high integration, simple and convenient operations of applications. According to practice, in addition to being well-adapted, this system is favorably reliable and stable.

Role of hepatitis B virus DNA integration in human hepatocarcinogenesis

Liver cancer ranks sixth in cancer incidence, and is the third leading cause of cancer-related deaths worldwide. Hepatocellular carcinoma (HCC) is the most common type of liver cancer, which arises from hepatocytes and accounts for approximately 70%-85% of cases. Hepatitis B virus (HBV) frequently causes liver inflammation, hepatic damage and subsequent cirrhosis. Integrated viral DNA is found in 85%-90% of HBV-related HCCs. Its presence in tumors from non-cirrhotic livers of children or young adults further supports the role of viral DNA integration in hepatocarcinogenesis. Integration of subgenomic HBV DNA fragments into different locations within the host DNA is a significant feature of chronic HBV infection. Integration has two potential consequences: (1) the host genome becomes altered (&#x0201c;cis&#x0201d; effect); and (2) the HBV genome becomes altered (&#x0201c;trans&#x0201d; effect). The cis effect includes insertional mutagenesis, which can potentially disrupt host gene function or alter host gene regulation. Tumor progression is frequently associated with rearrangement and partial gain or loss of both viral and host sequences. However, the role of integrated HBV DNA in hepatocarcinogenesis remains controversial. Modern technology has provided a new paradigm to further our understanding of disease mechanisms. This review summarizes the role of HBV DNA integration in human carcinogenesis.

Explicit frequency equations of free vibration of a nonlocal Timoshenko beam with surface effects

Considerations of nonlocal elasticity and surface effects in micro-and nanoscale beams are both important for the accurate prediction of natural frequency. In this study, the governing equation of a nonlocal Timoshenko beam with surface effects is established by taking into account three types of boundary conditions： hinged–hinged, clamped–clamped and clamped–hinged ends. For a hinged–hinged beam, an exact and explicit natural frequency equation is obtained. However, for clamped–clamped and clamped–hinged beams, the solutions of corresponding frequency equations must be determined numerically due to their transcendental nature. Hence, the Fredholm integral equation approach coupled with a curve fitting method is employed to derive the approximate fundamental frequency equations, which can predict the frequency values with high accuracy. In short,explicit frequency equations of the Timoshenko beam for three types of boundary conditions are proposed to exhibit directly the dependence of the natural frequency on the nonlocal elasticity, surface elasticity, residual surface stress, shear deformation and rotatory inertia, avoiding the complicated numerical computation.

Investigation on nonlinear multi-scale effects of unsteady flow in hydraulic fractured horizontal shale gas wells

A unified mathematical model is established to simulate the nonlinear unsteady percolation of shale gas with the consideration of the nonlinear multi-scale effects such as slippage, diffusion, and desorption. The continuous inhomogeneous models of equivalent porosity and permeability are proposed for the whole shale gas reservoir includ- ing the hydraulic fracture, the micro-fracture, and the matrix regions. The corresponding semi-analytical method is developed by transforming the nonlinear partial differential governing equation into the integral equation and the numerical discretization. The nonlinear multi-scale effects of slippage and diffusion and the pressure dependent effect of desorption on the shale gas production are investigated.

Frequency equations of nonlocal elastic micro/nanobeams with the consideration of the surface effects

A nonlocal elastic micro/nanobeam is theoretically modeled with the consideration of the surface elasticity, the residual surface stress, and the rotatory inertia,in which the nonlocal and surface effects are considered. Three types of boundary conditions, i.e., hinged-hinged, clamped-clamped, and clamped-hinged ends, are examined. For a hinged-hinged beam, an exact and explicit natural frequency equation is derived based on the established mathematical model. The Fredholm integral equation is adopted to deduce the approximate fundamental frequency equations for the clamped-clamped and clamped-hinged beams. In sum, the explicit frequency equations for the micro/nanobeam under three types of boundary conditions are proposed to reveal the dependence of the natural frequency on the effects of the nonlocal elasticity, the surface elasticity, the residual surface stress, and the rotatory inertia, providing a more convenient means in comparison with numerical computations.

CoB and BN composites enabling integrated adsorption/catalysis to polysulfides for inhibiting shuttle-effect in Li-S batteries

Lithium-sulfur(Li-S)batteries are hampered by the infamous shuttle effect and slow redox kinetics,resulting in rapid capacity decay.Herein,a bifunctional catalysis CoB/BN@rGO with integrated structure and synergy effect between adsorption and catalysis is proposed to solve the above problems.The integrated CoB and BN are simultaneously and uniformly introduced on the rGO substrate through a one-step calcination strategy,applied to modify the cathode side of PP separator.The transition metal borides can catalyze the conversion of lithium polysulfides(Li_(2)Sn,n≥4),whereas the bond of B-S is too weak to absorb LPS.Thus BN introduced can effectively restrict the diffusion of polysulfides via strong chemisorption with LiSnLi+…N,while the rGO substrate ensures smooth electron transfer for redox reaction.Therefore,through the integrated adsorption/catalysis,the shuttle effect is suppressed,the kinetics of redox reaction is enhanced,and the capacity decay is reduced.Using CoB/BN@rGO modified PP separator,the Li-S batteries with high initial capacity(1450 mAh g^(-1)at 0.35 mA cm^(-2))and long-cycle stability(700 cycles at 1.74 mA cm^(-2)with a decay rate of 0.032%per cycle)are achieved.This work provides a novel insight for the preparation of bifunctional catalysis with integrated structure for long-life Li-S batteries.

Synergistic effects of total ionizing dose and radiated electromagnetic interference on analog-to-digital converter

The influence of combined total ionization dose(TID)and radiated electromagnetic interference(EMI)in a commercial analog-to-digital converter(ADC)was studied.The degradation of the direct-current response,the static parameters,and the dynamic parameters caused by the TID and EMI separately and synergistically is presented.The experimental results demonstrate that the increase in TID intensifies data error and the signal-tonoise ratio(SNR)degradation caused by radiated EMI.The cumulative distribution function of EMI failure with respect to data error and SNR with different TIDs was extracted.The decreasing trend of the threshold was acquired with a small sample size of five for each TID group.The result indicates that the ADC is more sensitive in a compound radiation environment.

Effect of Machined Surface Integrity on Fatigue Performance of Metal Workpiece:A Review

Fatigue performance is a serious concern for mechanical components subject to cyclical stresses,particularly where safety is paramount.The fatigue performance of components relies closely on their surface integrity because the fatigue cracks generally initiate from free surfaces.This paper reviewed the published data,which addressed the effects of machined surface integrity on the fatigue performance of metal workpieces.Limitations in existing studies and the future directions in anti-fatigue manufacturing field were proposed.The remarkable surface topography(e.g.,low roughness and few local defects and inclusions)and large compressive residual stress are beneficial to fatigue performance.However,the indicators that describe the effects of surface topography and residual stress accurately need further study and exploration.The effect of residual stress relaxation under cycle loadings needs to be precisely modeled precisely.The effect of work hardening on fatigue performance had two aspects.Work hardening could increase the material yield strength,thereby delaying crack nucleation.However,increased brittleness could accel-erate crack propagation.Thus,finding the effective control mechanism and method of work hardening is urgently needed to enhance the fatigue performance of machined components.The machining-induced metallurgical structure changes,such as white layer,grain refinement,dislocation,and martensitic transformation affect the fatigue performance of a workpiece significantly.However,the unified and exact conclusion needs to be investigated deeply.Finally,different surface integrity factors had complicated reciprocal effects on fatigue performance.As such,studying the comprehensive influence of surface integrity further and establishing the reliable prediction model of workpiece fatigue performance are meaningful for improving reliability of components and reducing test cost.

Effect of Cadmium on Rat Leydig Cell Testosterone Production and DNA Integrity in vitro

Cadmium （Cd） is an elemental heavy metal with widely recognized toxicity. Its long-term use in industrial processes and daily activities has caused alarming levels of Cd contamination in the natural environment. According to the estimates by the Agency of Toxic Substances and Disease Registry in the US, 25 000 to 30 000 metric tons of Cd is annually released to the environment . Results of previous studies have demonstrated that several organs are targets of Cd, but the most important of these targeted organs may be the testes.

Influence of Tilted Angle on Effective Linear Energy Transfer in Single Event Effect Tests for Integrated Circuits at 130 nm Technology Node

A heavy-ion irradiation experiment is studied in digital storage cells with different design approaches in 130？nm CMOS bulk Si and silicon-on-insulator （SOI） technologies. The effectiveness of linear energy transfer （LET） with a tilted ion beam at the 130？nm technology node is obtained. Tests of tilted angles θ=0 ° , 30 ° and 60 ° with respect to the normal direction are performed under heavy-ion Kr with certain power whose LET is about 40？MeVcm 2 /mg at normal incidence. Error numbers in D flip-flop chains are used to determine their upset sensitivity at different incidence angles. It is indicated that the effective LETs for SOI and bulk Si are not exactly in inverse proportion to cosθ , furthermore the effective LET for SOI is more closely in inverse proportion to cosθ compared to bulk Si, which are also the well known behavior. It is interesting that, if we design the sample in the dual interlocked storage cell approach, the effective LET in bulk Si will look like inversely proportional to cosθ very well, which is also specifically explained.

Hybrid Kalman and unscented Kalman filters for INS/GPS integrated system considering constant lever arm effect

In inertial navigation system(INS) and global positioning system(GPS) integrated system, GPS antennas are usually not located at the same location as the inertial measurement unit(IMU) of the INS, so the lever arm effect exists, which makes the observation equation highly nonlinear. The INS/GPS integration with constant lever arm effect is studied. The position relation of IMU and GPS's antenna is represented in the earth centered earth fixed frame, while the velocity relation of these two systems is represented in local horizontal frame. Due to the small integration time interval of INS, i.e. 0.1 s in this work, the nonlinearity in the INS error equation is trivial, so the linear INS error model is constructed and addressed by Kalman filter's prediction step. On the other hand, the high nonlinearity in the observation equation due to lever arm effect is addressed by unscented Kalman filter's update step to attain higher accuracy and better applicability. Simulation is designed and the performance of the hybrid filter is validated.

The topological structure of the integral quantum Hall effect in magnetic semiconductor-superconductor hybrids

An unconventional integer quantum Hall regime was found in magnetic semiconductor-superconductor hybrids. By making use of the decomposition of the gauge potential on a U（1） principal fibre bundle over k-space, we study the topological structure of the integral Hall conductance. It is labeled by the Hopf index β and the Brouwer degree η. The Hall conductance topological current and its evolution is discussed.