INFLUENTIAL FACTORS COMBINATION AND COMPETITIVE ADVANTAGES IN STAGES OF URBAN COMPETITIVENESS——Case Study of Suzhou in China

The urban competitive advantages rely on the combination and interaction of influential factors. As a dynamic progressive process, the city at different time has different competition influential factors combination. Because of this, the urban competitive advantages take on time-series characteristics. Stages of urban competition can be summed up into three ones, the basic factor-driven, the investment-driven and the innovation-driven. The finding of the study on the stages of urban competitive advantages in Suzhou is that in the current stage of Suzhou its competitive advantage is the investment-driven. The investment, especially FDI, plays remarkable functions for Suzhou competition with other cities.

Calibration of LRFD Format for Steel Jacket OffshorePlatform in China Offshore Area(2): Load, Resistance and Load Combination Factors

Adopting the load and resistance factor design format, the design method for steel jaeket platform structures is developed. Firstly, the limit state equations and design format for steel jacket platform structures are introduced. Then, the ratio of live load effect to dead load effect is estimated. The target reliabilities for design of offshore structures in China offshore area are calibrated by past practice in API RP2A-WSD code. The load and resistance factors are optimized by minimizing the difference within the target reliability and the resulting reliability over the range of load effect ratios. Considering the concurrence of different loads, load combination factors are obtained through an optimization process, and the relation between the load combination factor and load correlation coefficient is established. Finally, the design formulae for steel jacket structures in China offshore area are recommended.

An improved displacement-based adaptive pushover procedure based on factor modal combination rule

An accurate estimation of the applied load pattern is an essential component in each pushover procedure. Recently, a number of adaptive pushover methods have been proposed in which the effects of the higher modes as well as the progressive changes in the dynamic characteristics of structures are taken into account to compute the applied load pattern. The basic shortcoming of these advanced pushover methods is related to employing the quadratic modal combination rule, whereby the sign reversals of the modal load vectors are suppressed. In this study, an improved displacement-based adaptive pushover method is developed in which the applied load pattern is computed using the factor modal combination rule(FMC). In the proposed procedure, multiple load patterns, depending on the number of the modes considered, are determined in order to take into account the sign reversals of different modal load vectors. The accuracy of the proposed method is verifi ed for seven moment resisting frame buildings of 3, 9 and 20 stories with regularity or vertically geometric and mass irregularities subjected to 60 earthquake ground motion records. The results showed that the proposed methodology is capable of reproducing the peak dynamic responses with very good accuracy.

Reliability-Based Load and Resistance Factors Design for Offshore Jacket Platforms in the Bohai Bay:Calibration on Design Factors

For the fulfillment of the probability-based structural design for the offshore jacket platforms in the Bohai Bay, the design factors of loads, resistance and load combinations are much necessary to be calibrated according to the proposed target reliability index. Firstly, the limit states function for the offshore jacket platforms is introduced. Then, four approaches to calibrate the factors of load and resistance are presented and compared. Afterwards, the methods to calibrate the load combination factors are developed. Finally, the factors of load, resistance and load combination for the offshore jacket platforms in the Bohai Bay are calibrated and the corresponding design formulae are recommended. The results are proved to be rational in practice, and also illustrate that the proposed target reliability index for offshore jacket platforms in the Bohai Bay is also appropriate.

Risk factors and ankle brachial indexes in cerebral infarction combined with peripheral arterial disease

BACKGROUND: Ankle brachial index (ABI) is widely involved in researches and clinical application of peripheral vascular injury of patients with diabetes mellitus (DM); however, the application in cerebral infarction (CI) is rare. OBJECTIVE: To investigate the possible risk factor of cerebral infarction plus peripheral arterial disease (PAD), compare metabolic characteristics of patients who having CI plus PAD or only having CI, and understand the significance of ABI on screening and diagnosing CI plus PAD of lower limb. DESIGN: Contrast observation based on CI patients. SETTING: Department of Neurology, Nanxishan Hospital of Guangxi Zhuang Autonomous Region. PARTICIPANTS: A total of 124 CI patients were selected from Department of Neurology, Nanxishan Hospital of Guangxi Zhuang Autonomous Region from July 2005 to April 2006, including 72 males and 52 females aged from 45 to 88 years. All patients met the diagnostic criteria of cerebrovascular disease established by National Academic Conference of Cerebrovascular Diseases in 1995 and determined as cerebral infarction with MRI or CT examination. All patients provided informed consent. There were 46 cases (37.2%) with CI plus PAD and 78 cases (62.8%) only with CI. METHODS: Blood pressure of bilateral ankles and upper extremities was measured at plain clinostatism with DINAMAP blood pressure monitor (GE Company). The ratio between average systolic pressure of lateral ankle and average systolic pressure of both upper extremities was regarded as ABI. The normal ABI was equal to or more than 0.9. If ABI < 0.9 occurred at one side, patients were diagnosed as PAD. On the second morning after hospitalization, blood was collected to measure fasting blood glucose (FBG), 2-hour postprandial blood glucose (PBG2h), glycosylated hemoglobin (HbA1c), triglycerides (TG), total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C) and low-density lipoprotein cholesterol (LDL-C). Among them, blood glucose, lipid and other biochemical markers were measured with enzyme chemistry assay and HbA1c was measured with HbA1c meter based on high liquid phase. Measurement data and enumeration data were compared with t test and Chi-square test, and multiple factors were dealt with Logistic regression analysis and multivariate linear regression analysis. MAIN OUTCOME MEASURES: Results of correlation between ABI and metabolic markers with multivariate linear regression analysis; risk factors of CI plus PAD with Logistic regression analysis; comparisons of metabolic markers between PAD and non-PAD patients. RESULTS: All 124 patients with acute CI were involved in the final analysis. ① Comparisons of metabolic markers: Levels of serum LDL-C and uric acid (UA) were higher of PAD patients than those of non-PAD patients (t =2.051 9, 3.339 1, P < 0.05); however, there were no significant differences among other metabolic markers (P > 0.05). ② Results of multivariate linear regression analysis: PBG2h, LDL-C and UA were obvious correlation with ABI of posterior tibial artery of lower limb and dorsal pedis artery (partial regression coefficient = -0.231 to -1.010, P < 0.05). ③ Risk factors of CI plus PAD with Logistic regression analysis: Age, smoking history, sum of CI focus (≥3) and LDL-C were independent risk factor of CI plus PAD (OR =1.524-5.422, P < 0.05-0.01). CONCLUSION: ① Levels of serum LDL-C and UA of patients with CI plus PAD are high. ② ABI of lower limbs is correlation with PBG2h, LDL-C and UA. In addition, measuring ABI is beneficial for early diagnosing PAD of lower limbs of patients who have poorly controlled blood glucose, abnormal lipid and poor renal function. ③ Age, LDL-C and sum of CI focus (≥3) are independent risk factors of CI plus PAD. It is of significance for screening non-PAD patients to evaluate risk degrees and prognosis and select therapeutic methods based on ABI measurement.

FINITE ELEMENT METHOD COMBINED WITH DYNAMIC PHOTOELASTIC ANALYSIS TO DETERMINE DYNAMIC STRESS-INTENSITY FACTORS

The present paper is addressed to the finite element method combined with dynamic photoelastic analysis of propagating cracks, that is, on the basis of [1] by Chien Wei-zang, finite elements which incorporate the propagating crack-tip singularity intrinsic to two-dimensional elasticity are employed. THe relation between crack opening length and time step obtained from dynamic photoelaslie analysis is used as a definite condition for solving the dynamic equations and simulating the crack propagations as well As an example, the impact response of dynamie-bending-test specimen is investigated and the dynamic stress-intensity factor obtained from the mentioned finite element analysis and dynamic photoelasticity is in reasonable agreement with each other.

混配农药中毒防治研究

首次在我国开展大规模的混配农药中毒流行病学调查,发现接触混配农药是当前发生农药中毒的重要危险因素,为针对性的预防提供了科学依据。毒理学研究证实多数农药混剂呈增毒效应或协同作用,且与其毒代动力学变化有密切关系,为今后开发高效、低毒的混配农药提供了毒理学依据。在国内外首次建立甲基对硫磷单克隆抗体酶联免疫测定法,并成功研制便携式血胆碱酯酶快速测定仪;这些检测接触、效应生物标志物的灵敏、特异、便捷的方法已试用于现场,并具有开发为产品的前景。同时还发现对氧磷酶基因在192位点的单核苷酸多态性,可能是甲基对硫磷免疫毒性作用的易感性生物标志物之一。在总结不同类别农药混配后所致中毒的临床表现特点和规律的基础上,修订现行的农药中毒诊断标准,增添了有机磷单剂及混剂中毒所致“中间期肌无力综合征”的新内容,将提高我国农药中毒的诊治水平。本研究主要成果达国内领先和国际先进水平。

A COMBINED TECHNIQUE FOR SOLUTION OF PDE＇s VIA THE GENERALIZED DOMAIN DECOMPOSITION METHOD

The Domain Decomposition Method(DDM) is a powerful approach to solving maily types of PDE's. DDM is especially suitable for massively Parallel computers. In the past, most research on DDM has focused on the domain splitting technique. In this paper. we focus our attention on use of a combination of techniques to solve each subproblem. The central question with DDM is that of how to doal with the pseodoboundary conditions. Here, we introduce a set of operators which act on the pseudo-boundaries in the solution process, referring to this new. procedure as the 'Generalized Domain Decomposition A.Jlethod(GDDM).' We have already obtained convergence factors for GDDM with certain classes of PDE's. These ctonvergence factors show that we can derive exact solutions of the whole problem for certain types of PDE's, and can get superior speed of convergence for other types.

THE THREE-DIMENSIONAL STRESS INTENSITY FACTOR UNDER MOVING LOADS ON THE CRACK FACES

The dynamic stress intensity factor history for a half plane crack in an otherwise unbounded elastic body,with the crack faces subjected to a traction distribution consisting of two pairs of combined mode point loads that move in a direction perpendicular to the crack edge is considered.The analytic expression for the combined mode stress intensity factors as a function of time for any point along the crack edge is obtained.The method of solution is based on the application of integral transform together with the Wiener-Hopf technique and the Cagniard-de Hoop method. Some features of the solution are discussed and graphical results for various point load speeds are presented.

Soil particle and moisture-related factors determine landward distribution of bacterial communities in a lateral riverside continuum of the Xilin River Basin

Continuous landscape components along the lateral riverside are affected by both hydrologic connectivity and disconnectivity.In recent years,anthropogenic activities and climate changes have caused wetland shrinkage and land degradation along the lateral riverside of many arid and semiarid regions.Since microorganisms are major drivers of soil biochemical cycling,it is essential to examine soil microbial communities along the lateral landscape continuum to understand their ecosystem functioning and predict future land changes.Here,we collected samples along a lateral riverbed center-riverbed edge-oxbow lake-floodplain-terrace continuum(i.e.,landward distribution)in the Xilin River Basin,Inner Mongolia,China.The floodplain had the highest microbial diversity and heterogeneity,with Bacteroidetes,β-andγ-Proteobacteria being the most abundant taxa.In contrast,the terrace had the lowest microbial diversity and heterogeneity,with Acidobacteria,Actinobacteria,Verrucomicrobia,Gemmatimonadetes,andα-Proteobacteria as the most abundant taxa.Silt particle,salinity,and moisture were the most influential factors for landward variation of bacterial communities along the riverside continuum.Altogether,we demonstrate that dominant bacterial lineages,soil particles,and moisture-related factors are valuable indicators of this continuum,which can be leveraged for the early prediction of drought-induced wetland shrinkage and grassland desertification.

Efficacy and safety analysis of the combination of cladribine,cytarabine,granulocyte colony stimulating factor( CLAG ) regime in patients with refractory or relapsed acute myeloid leukemia

Objective To analyze efficacy and safety of CLAG regimen in patients with refractory or relapsed acute myeloid leukemia(AML).Methods Efficacy and adverse events of patients with refractory or relapsed AML who were treated with one course of CLAG from April 1st,2014 through December 9th,2015 in our hospital were retrospectively reviewed.Results Thirty-three

Understanding Strategic Behavior:A Preliminary Analytical Framework

To understand complex state behavior, a detailed study of strategic behavior is needed. To get rid of what is out-of-date and take in fresh perspectives, we need to eliminate the current methodological bottleneck and take full advantage of multivariate research methods to explore the complex interactions among variables and develop a basic analytical framework. First, strategic behavior should be divided into four stages, i.e., strategic assessment, strategic decision-making, strategic mobilization and strategic implementation, then the factors affecting each stage should be clarified and their interactions grasped. A preliminary framework for understanding state strategic behavior will help to promote the in-depth development of this field of research.

Effects of Arsenic on Cell Proliferation and Its Related Gene Expression in Human Epidermal Keratinocyte

Objective:To study the effects of low concentration of ar senic (As 2O 3) on DNA synthesis and related transcription factor gene E2F1 express ion in keratinocyte. Methods:Human epidermal keratinocyte (cell line HaCaT) cultured in vitro was used. After treatment with various concentrations of arsenic, DNA s ynthesis and E2F1 expression in HaCaT cells were detected by using 3H-TdR method and RT-PCR.Results:Arsenic caused a modest increase of keratinocyte DNA synth esis when the concentration reached the range within 0.5-16 nmol/L, but the amo unt of incorporated 3H-TdR decreased and returned to baseline level when th e concentration of arsenic increased to over 16 nmol/L. RT-PCR analysis showe d the level of E2F1 mRNA was elevated in HaCaT cells with the increase of DNA sy nthesis. Conclusion:Arsenic of a certain concentration could increase DNA s ynthesis and enhance E2F1 expression in HaCaT cell line, which might be one of t he pathological mechanisms of skin disease related to arsenic.

Retrospective analysis of 67 consecutive cases of pure ovarian immature teratoma

To investigate the development regularity, treatment methods and prognosis of ovary immature teratoma (POIT) Methods Sixty seven patients with POIT, admitted from 1958 to 1998, were retrospectively analyzed There were 31 patients with stage Ⅰ, 4 with stage Ⅱ, 2 with stage Ⅲ and 1 with stage Ⅳ lesions Twenty seven patients had recurrences and 2 had distant metastases Unilateral adnexectomy was performed for stage Ⅰ lesions From the 1980s, this was followed by four cycles of combination chemotherapy (VAC, PVB or BEP×3 cycles) as post operative adjuvant therapy Combined chemotherapy and multiple operations were performed for advanced and recurrent lesions Results The overall survival rate was 75% (50/67) However, there was a remarkable difference in the results from the various periods From 1958 to 1983, the 5 year survival rate was 40% (6/15), and it was raised to 79% (26/33) from 1984 to 1993 In the period 1994 to 1998, 95% (18/19)of patients were rescued Thirty five patients who had early lesions (stage Ⅰ and Ⅱ) had a 5 year survival rate of 91 4% (32/35) Thirty two patients with recurrent or advanced lesions had a 5 years survival rate of 56% (18/32) There were 8 patients with grade Ⅲ tumors and their 5 year survival rate was only 25% (2/8) The chief prognostic factors for this disease are clinical stage, pathological grade and adequate treatment Conclusion POIT is a potentially curable disease in today’s practice It is characterized by the fact that recurrent tumors may be converted back to mature ones as time goes on With chemotherapy, these is a good opportunity to rescue those patients with recurrent tumors At present, treatment of POIT gives the most satisfactory results among all malignant ovarian germ cell tumor types Tests of serum specific tumor markers (CA19 9, AFP, CA125, CEA) performed preoperatively or before chemotherapy and during follow up have been found helpful in the evaluation of prognosis