Study on the Biological Basis of Qi, Blood, and Vessel in Immune Thrombocytopenia Patients With Syndrome of Qi Failing to Govern Blood Based on the Theory of Qi and Blood

Objective: To investigate the biological basis of qi, blood and vessel in immune thrombocytopenia(ITP) patients with syndrome of qi failing to govern blood(SQFGB) based on traditional Chinese medicine.Methods: A total of 52 ITP patients with SQFCB were enrolled and divided into bleeding group(38 cases) and non-bleeding group(14 cases).Bleeding group was further divided into mild qi deficiency group(25 cases) and moderate/severe qi deficiency group(13 cases) based on Chinese Medicine syndrome score.20 healthy volunteer were recruited as control group.The count of platelet(PLT) was taken as the blood related indicator.The expressions of cytokines including IL-1β, IL-17 A, TNF-α, CD40 L, and TGF-β, detected by Aim Plex Multiple Immunoassays for Flow, were taken as the qi related indicators.The expressions of VEGF-A, detected by Aim Plex Multiple Immunoassays for Flow and NO, NOS, and ET-1 detected by ELISA, were taken as the vessel related indicators.Results: As compared to the control group, the count of PLT, taken as the blood related indicator, was significantly lower in ITP group patients with SQFCB(P<0.05).The expression levels of IL-17 A and TNF-α, taken as the qi related indicators, were significantly higher, while those of CD40 L, IL-1β, and TGF-β, also taken as the qi related indicators, were significantly lower in ITP patients with SQFCB, respectively(P<0.05).The expression levels of NO and ET-1, taken as the vessel related indicators, were significantly higher, while the expression levels of NOS and VEGF-A also taken as the vessel related indicators, were significantly lower in ITP patients with SQFCB, respectively(P<0.05).The count of PLT, taken as the blood related indicator, was significantly lower in moderate/severe group than those in mild group(P<0.05).The expression levels of CD40 L and TGF-β, taken as the qi related indicators, were also significantly lower in moderate/severe group than those in mild group, respectively(P<0.05).Conclusion: The count of PLT might be the biological basis of blood.The expressions of NO, NOS, ET-1 and VEGF-A might be the biological basis of vessel.The expressions of IL-1β, IL-17 A, TNF-α, TGF-β, and CD40 L may be the biological basis of qi.The expressions of CD40 L and TGF-β could reflect the degree of qi deficiency in ITP patients based on the theory of qi and blood.

Clinical observation of pediatric Tuina plus oral Chinese medication for pediatric anorexia due to spleen failing in transportation

Objective To observe the clinical efficacy of pediatric Tuina(Chinese therapeutic massage)plus oral administration of Chinese medication for pediatric anorexia due to spleen failing in transportation.Methods A total of 94 children with anorexia due to spleen failing in transportation were randomized into an observation group and a control group by the random number table method at a ratio of 1:1,with 47 cases in each group.The control group was treated with modified Bu Huan Jin Zheng Qi San,and the observation group was treated with additional Tuina manipulation of Yun Shui Ru Tu based on the treatment in the control group.After 4 weeks of treatment,the clinical efficacy of the two groups was observed,and the traditional Chinese medicine(TCM)symptom score,serum leptin,neuropeptide Y,and serum zinc and calcium levels were compared.Results After 4 weeks of treatment,the total effective rate of the observation group was 87.2%,and that of the control group was 74.5%.The difference between the two groups was statistically significant( P<0.05).After treatment,the TCM symptom scores in both groups decreased significantly(P<0.05),and the scores in the observation group were lower than those in the control group(P<0.05).After treatment,the serum leptin level in both groups decreased,and the level in the observation group was lower than that in the control group(P<0.05).The serum neuropeptide Y,zinc,and calcium levels in both groups increased after treatment,and the levels in the observation group were higher than those in the control group(P<0.05).Conclusion Tuina manipulation of Yun Shui Ru Tu plus oral administration of Chinese medication is significantly effective in treating pediatric anorexia due to spleen failing in transportation,which can improve the appetite of children and improve the symptoms of anorexia,and the curative effect is better than that of oral administration of Chinese medication alone.

Science Magazines:A Failing Experiment

The Chinese edition of Scientific American, printed every month for 27 years, ceased publication at the end of 2005 when its American partner decided to quit the copyright cooperation. According to Zhou Guozhen, former chief editor of the magazine, it was the low circulation in China that finally persuaded the Americans to kill the deal. Although

The safety and effectiveness of once daily detemir in patients with type 2 diabetes previously failing oral agents:the Chinese cohort from SOL-VE^(TM) observational study

Objective To evaluate the safety and effectiveness of initiating once-daily insulin detemir(Levemir) as add-on therapy in patients with type 2 diabetes mellitus(T2DM) who failed treatment of oral anti-diabetic drugs(OAD).Methods The present study was derived from the data

Conversion hip arthroplasty for failed nailing of intertrochanteric fracture: Reflections on some important aspects

In this editorial,I present my comments on the article by Solarino et al.Conversion hip arthroplasty,which is an optional salvage procedure performed following unsuccessful fixation of intertrochanteric femur fractures in elderly pati-ents,entails more complex processes and higher rates of operative complications than primary arthroplasty.Hence,it is important to consider the appropriateness of the primary treatment choice,as well as the adequacy of nailing fixation for intertrochanteric fractures.This article briefly analyzes the possible factors contributing to the nailing failure of intertrochanteric fractures and attempts to find corresponding countermeasures to prevent fixation failures.It also analyzes the choice of treatment between nailing fixation and primary arthroplasty for intertrochanteric fractures.

A Method for Forecasting Failures of Sucker Rod-pumped Wells

An exact forecast of the failures of a sucker rod-pumped well in a production area means much for an oilfield’s operation budget, operational arrangement and production plan. In this paper, according to the characteristics of failed sucker rod-pumped well randomness and strong outburst, with the gray GM (1,1) forecast model and the Markov forecast model combined, gray GM (1,1) forecast model is utilized to handle the primary data of an oilfield, and Markov forecast model is utilized to calculate the state transfer probability of forecast value. Then, the gray Markov forecast model considering the influence of randomness factors is formed. Field results prove that the calculation precision of this method is higher and the practicability is greater.

签名次数受限的代理签名方案

在代理签名方案中,合理地限制代理签名人的签名权力是一个重要的问题。基于前向安全技术和Fail-Stop签名方案提出了一个n次代理签名方案。在该方案中,原始签名人可以事先限定代理签名的次数。若代理签名人重复使用同一次代理密钥,则将面临代理签名者的密钥被破解的危险。如果超过使用次数的限制,则将无法进行有效的代理签名。

Stability study on naturally filling body in gob-side entry retaining

In the construction of the filling gob-side entry retaining in a lane, we utilize the self-slide natural phenomenon of a falling gangue in an inclined coal seam goaf. First, we put the falling gangue of goal above the laneway and made it the main filling material by adopting the measurement of flexible supporting system combined with those of rigid supporting system. Then we made the filling material gunited and solidified to maintain the filling goal of the gob-side entry retaining beside the lane. Considering the law of energy conservation and law of pressure distribution for retaining the active and Static soil of the wall, we analyzed the reliability of a gangue blocking facilities and the stability of the filling mate- rial in the lane. We analyze the figures to see the stability. The result shows that the gangue block sup- porting system is reliable, and has been successfully practically applied.

Climate Change and CO₂Removal from the Atmosphere

Several methods have been proposed in recent years to counteract climate change and ocean acidification by removing CO2 from the atmosphere (Carbon Dioxide Removal). The most versatile and widely applicable of these methods is enhanced weathering of olivine, which is capable of removing billions of tons of CO2 from the atmosphere at moderate cost compared to the high cost of Carbon Capture and Storage (CCS). Despite its disadvantages, CCS is still the favored solution of many governments. Many misunderstandings of the potential of enhanced weathering persist. This paper addresses some of these misunderstandings, mainly caused by models which ignore established facts.

LEARNING WITH ERROR BASED SEARCHABLE ENCRYPTION SCHEME

A learning with error problem based encryption scheme that allows secure searching over the cipher text is proposed. Both the generation of cipher text and the trapdoor of the query are based on the problem of learning with errors. By performing an operation over the trapdoor and the cipher text, it is able to tell if the cipher text is the encryption of a plaintext. The secure searchable encryption scheme is both cipher text and trapdoor indistinguishable. The probabilities of missing and failing match occurrence in searching are both exponentially small.

泰科PB840呼吸机故障维修

1故障一ICU840呼吸机使用中报＂no are supply＂无空气供给,使患者下机,做小自检SST。 SST flow sensor test报as0013 wall air pressure not detected（墙壁空气压力没有发现）。 做大自检EST： （1）cicuit pressure test passed; （2）flow sensors cross check test failed AE0111 unable to establish air flowAE0107。

基于数据仓库汽车零部件失效诊断研究

本文以汽车零部件的失效诊断为技术背景,根据失效诊断技术过程,提出了失效诊断数据仓库的功能架构,描述了集成化建模方法,对数据的收集、集成、存储、管理等方面进行研究,以提高数据仓库的准确度,并提供了基于此架构的系统实现案例,指出了要进一步研究的问题。为汽车零部件失效诊断数据仓库建设提供了一种实用而有效的新途径。

Appropriate Heart Rate in a Patient with Repaired Tetralogy of Fallot

Appropriate heart rate in a failing pulmonary ventricle remains unknown, particularly in congenital heart diseasewith unique hemodynamics. A 71-year-old male with repaired tetralogy of Fallot and a pacemaker for a sinusnode dysfunction suffered from heart failure symptoms with preserved left ventricular function. Simply changingthe pacemaker’s lower rate from 60 to 75 bpm, New York Heart Association classification improved from III to II,and hemodynamic parameters drastically improved. We regarded this case as informative. Appropriate heart ratecould be higher in congenital patients with failing right and non-failing left ventricles than in adults with malfunctioningLV.

Unexpected Hypertensive Pneumothorax after Digestive Upper Endoscopy: A Case Report

We report an unexpected massive left pneumothorax at the end of a digestive upper endoscopy without evidences of perforation or airway over-pressure. The possible air passage through a diaphragmatic failing is discussed.

柯达相机DV5700报21-116和吸双片问题

故障现象：机器原来主要是会报116（Film Pickup Failed）,117（Film Pickup Retry Notification,Code 21-116is generated on the third successive failed pickup attempt.）,因是早期设备,怀疑Pickup上的传感器连线断,于是更换了新的Pickup,换后同样会报116,117,并出现双片现象。

增强型fail-stop签名方案的安全性分析

本文介绍一种可证明的安全签名方案:fail-stop签名方案。它是一种安全性增强的一次签名方案,该方案仅给一则消息签名时是安全的,它不能同时给两则消息同时签名,必须一次一签,密钥使用过后必须扔掉,可以进行任意次的验证,有较高的安全性和实用性。本文对fail-stop签名系统的安全性进行了分析和评估,提出了一种伪造证明算法,签名者能够以高概率证明签名的真伪。

粉胶比对橡胶沥青胶浆高温性能的影响研究

为了研究不同粉胶比对橡胶沥青胶浆高温性能的影响,选择石灰岩矿粉作为填料,粉胶比掺量为0.2、0.4、0.6、0.8。胶浆高温性能的评价指标选择Fail temperature和ZSV,通过DSR试验对不同胶浆进行研究。试验结果表明:随着粉胶比的增加,橡胶沥青胶浆的Fail temperature和ZSV值均逐渐变大,而且增大幅度较大,橡胶沥青胶浆的高温性能得到明显的改善;利用环境扫描电镜对胶浆进行扫描,发现添加矿粉的橡胶沥青胶浆光滑、细腻,矿粉被橡胶沥青裹覆均匀。

Failed medial patellofemoral ligament reconstruction:Causes and surgical strategies

Patel ar instability is a common clinical problem encountered by orthopedic surgeons specializing in the knee. For patients with chronic lateral patellar instability, the standard surgical approach is to stabilize the patella through a medial patellofemoral ligament(MPFL) reconstruction. Foreseeably, an increasing number of revision surgeries of the reconstructed MPFL will be seen in upcoming years. In this paper, the causes of failed MPFL reconstruction are analyzed:(1) incorrect surgical indication or inappropriate surgical technique/patient selection;(2) a technical error; and(3) an incorrect assessment of the concomitant risk factors for instability. An understanding of the anatomy and biomechanics of the MPFL and cautiousness with the imaging techniques while favoring clinical over radiological findings and the use of common sense to determine the adequate surgical technique for each particular case, are critical to minimizing MPFL surgery failure. Additionally, our approach to dealing with failure after primary MPFL reconstruction is also presented.

Failed biliary cannulation: Clinical and technical outcomes after tertiary referral endoscopic retrograde cholangiopancreatography

AIM: Prospective evaluation of repeat endoscopic retrograde cholangiopancreatography (ERCP) for failed Schutz grade 1 biliary cannulation in a high-volume center. METHODS: Prospective intention-to-treat analysis of patients referred for biliary cannulation following recent unsuccessful ERCP. RESULTS: Fifty-one patients (35 female; mean age: 62.5 years; age range: 40-87 years) with previous failed biliary cannulation were referred for repeat ERCP. The indication for ERCP was primarily choledocholithiasis (45%) or pancreatic malignancy (18%). Successful biliary can- nulation was 100%. The precut needle knife sphincterotomy (NKS) rate was 27.4%. Complications occurred in 3.9% (post-ERCP pancreatitis). An identif iable reason for initial unsuccessful biliary cannulation was present in 55% of cases. Compared to a cohort of 940 nave pa-pilla patients (female 61%; mean age: 59.9 years; age range: 18-94 years) who required sphincterotomy over the same time period, there was no statistical difference in the cannulation success rate (100% vs 98%) or postERCP pancreatitis (3.1% vs 3.9%). Precut NKS use was more frequent (27.4% vs 12.7%) (P = 0.017). CONCLUSION: Referral to a high-volume center following unsuccessful ERCP is associated with high technical success, with a favorable complication rate, compared to routine ERCP procedures.