Far Infrared Ray Radiation Inhibits the Proliferation of A549, HSC3 and Sa3 Cancer Cells through Enhancing the Expression of ATF3 Gene

Far-infrared ray (FIR) is electromagnetic wave between 4 and 1000 μm. FIR causes heating, but how it affects cells is not well understood. In this study, we developed a culture incubator that can continuously irradiate cells with FIR and examined the effects of FIR on five human cancer cell lines, namely A431 (vulva), A549 (lung), HSC3 (tongue), MCF7 (breast) and Sa3 (gingiva). We found that FIR inhibits cell proliferation and induces cell hypertrophy without apoptosis in A549, HSC3 and Sa3 cells. Flow cytometry revealed that the inhibition of proliferation was due to G2/M arrest. Contrary, FIR did not inhibit cell proliferation and cause cell hypertrophy in A431 or MCF7 cells. Microarray analysis revealed that FIR suppressed the expression of cell proliferation-related and stress-responsive genes in FIR-sensitive cell lines (A549, HSC3 and Sa3). ATF3 in particular was identified as a key mediator of the FIR effect. Over-expression of ATF3 inhibited cell proliferation and knockdown of ATF3 mRNA using an antisense oligonucleotide suppressed FIR-induced growth arrest. These results indicate that a body temperature range of FIR radiation suppresses the proliferation of A549, HSC3, Sa3 cells and it appears that ATF3 play important roles in this effect.

Instability of Nucleic Acids in Airborne Microorganisms under Far Infrared Radiation

Emergence of zoonotic-human pathogens is proven to be a lethal threat to public health, and RNA virus including influenza viruses, severe acute respiratory syndrome coronavirus, middle east respiratory syndrome coronavirus, and COVID-19, plays a pivotal role. As those viruses as airborne microorganisms spread mainly by tiny airborne particles, it is important to de-active those airborne particles before their entry into human bodies. In this study, we investigated the effect of far infrared (FIR) radiation on inhibition of airborne microorganisms. The result confirmed that double stand DNA from airborne microorganisms containing RNA viruses was stable under mild FIR radiation. However, single strand RNA from them was found to be sensitive to FIR radiation, indicating that RNA virus in airborne particles is instable under FIR radiation. Based on this observation, two models on usage of FIR radiation to prevent RNA virus transmission by air and cure RNA virus infection were proposed. Then, this study suggests that FIR radiation has the potential to be a cheap, convenient, and efficient method in clinic to treat RNA virus.

Physiological benefits of ambient far infrared energy within the 4-24 micron range

Far infrared(FIR)radiation(3-100µm)is an electromagnetic spectrum commonly studied for biological effects.This article aims to discuss using Far infrared radiation with sub-division(4-24µm)of this waveband to stimulate tissues and cells and is considered an effective therapeutic modality for specific medical disorders.The IR application as a medical therapy has advanced rapidly in recent years.For example,IR therapy like IR-emitting apparel and materials that can be run solely by body heat(does not need an external power supply)have been developed.New methods for providing FIR radiation to the human body have emerged due to technological advancements.Specialty saunas and lamps that emit pure FIR radiation have become effective,safe,and widely used therapeutic sources.Fibers infused with thermide,FIR emitting ceramic nanomaterials and knitted into fabrics are used as clothes and apparel to produce FIR radiation and benefit from its effects.A deeper understanding of FIR's significant innovations and biological implications could aid in improving therapeutic efficacy or developing new methods that use FIR wavelengths.

石墨烯低温远红外辐射干燥稻谷干燥特性与品质研究

为研究稻谷的石墨烯低温远红外干燥特性及其对稻谷干燥品质的影响,以辐射温度、排粮流量和除湿风量为影响因素,以整精米率和应力裂纹指数增值为评价指标,用自制的循环式石墨烯低温远红外干燥机进行稻谷干燥试验,通过BBD(Box-Behnken设计)响应面法,分析了低温远红外干燥对稻谷干燥品质的影响以及工艺参数优化。结果表明:影响稻谷干燥特性和品质的最主要因素是辐射温度,其次是排粮流量和除湿风量。随着辐射温度的升高,稻谷干燥速率和应力裂纹指数增值逐步增大,整精米率则逐步降低。与同温度的热风干燥相比,石墨烯低温远红外干燥平均干燥速率和干燥品质均有显著提高。经优化后,稻谷最佳石墨烯低温远红外干燥工艺条件为:辐射温度43℃、排粮流量4 kg/min、除湿风量193 m^(3)/h,此时应力裂纹指数增值为9,整精米率为79.75%,稻谷干燥品质最佳。这说明利用石墨烯低温远红外干燥稻谷,可以明显提高干燥速率并改善稻谷干燥品质。

Effect of far infrared radiation ceramics containing rare earth additives on surface tension of water

A kind of far infrared radiation ceramics was prepared by using silicate minerals, calcium carbonate and silicon dioxide as main raw materials, and cerium nitrate as additive. The structure of the ceramics and far infrared radiation properties on the surface tension of water were characterized by X-ray diffraction, scanning electron microscopy, Fourier transform infrared spectroscopy and a tensiometer, respectively. It was showed that, after being sintered at 1160 ℃, the solid solution was formed by CeO2 and Fe2O3, thus the crystal parameters （c/a axis ratio） and interplanar spacing of Fe2O3 increased. The addition of cerium was regarded to improve the far infrared radiation of ceramics, and the maximum emissivity value in the range of 5-20 μm was 0.94. The surface tension of water gradually decreased with increasing radiation time.

五步健瘘操配合远红外线照射干预对血液透析患者动静脉内瘘的治疗效果观察

目的探讨五步健瘘操+远红外线照射干预在血液透析(HD)患者动静脉内瘘(AVF)中的应用成效。方法选择2020年3月~2023年4月本院收治的50例HD患者,按随机数字表法分为观察组和对照组,每组25例。对照组实施常规干预性指导,观察组实施五步健瘘操配合远红外线照射干预。对比两组患者AVF成熟时间、并发症发生情况以及干预前后的穿刺疼痛程度、透析情况、生存质量。结果观察组AVF成熟时间为(36.33±4.62)d,短于对照组的(58.52±5.31)d(t=15.763,P=0.000<0.05)。干预后,两组患者视觉模拟评分法(VAS)评分均低于干预前,且观察组VAS评分(1.67±0.23)分低于对照组的(2.26±0.39)分(P<0.05)。干预后,观察组血管内径(6.62±0.75)mm大于对照组的(5.75±0.60)mm,透析血流量(271.75±17.44)ml/min高于对照组的(256.57±18.37)ml/min(P<0.05)。干预后,观察组社会功能评分(76.79±6.92)分、物质生活评分(78.74±7.33)分、躯体评分(81.86±6.85)分、心理评分(81.86±7.33)分均高于对照组的(69.65±6.68)、(70.78±6.98)、(72.74±6.68)、(72.78±6.95)分(P<0.05)。观察组并发症发生率4.00%低于对照组的32.00%(P<0.05)。结论五步健瘘操配合远红外线照射干预在HD患者中具有较好的应用效果,利于缩短其AVF成熟时间,减轻穿刺疼痛程度,改善透析情况,降低并发症发生率,提升生存质量。

南瓜片超声-远红外辐射干燥特性及微观结构

为了探索直触式超声强化远红外辐射干燥的干燥特性,该文以南瓜片为试材,利用超声-远红外辐射干燥设备,研究了不同超声功率及远红外辐射温度对干燥时间、干燥速率、扩散系数、微观结构以及能耗的影响。结果表明,远红外辐射板温度越高,热效率越高,有利于提高干燥速率及缩短干燥时间;在辐射板温度为200℃的条件下,超声功率为30、60 W时南瓜片所需干燥时间比未加超声所需干燥时间分别缩短了13.3%、26.7%,平均干燥速率分别提高了15.2%、36.1%,说明将物料直接放在超声辐射板上,可实现对物料内部传质过程的有效强化,但超声强化效果随着物料含水率的降低而减弱;有效水分扩散系数的数值在0.98×10-9-2.85×10-9 m2/s之间;提高超声功率可增加物料表面与物料内部的微细孔道尺寸与数量;提高远红外辐射温度会导致物料表面及内部热源区域中微细管道的扩张与增多;将远红外辐射加热技术与超声强化技术联合用于干燥,可对物料内部微观结构及质热传递产生协同强化;采用直触式超声技术对远红外辐射干燥过程进行强化,可降低干燥能耗6.67%-20.21%。远红外辐射温度在200-240℃、超声功率在30-60 W时,可以实现较快的干燥速率、较低的干燥能耗。研究结果可为超声-远红外辐射干燥技术的研究与应用提供参考。

聚酯纤维的负离子释放功能化改性及表征

以聚酯纤维为研究对象,对其进行了表面电气石负载改性整理,以增加聚酯纤维的远红外辐射率和负离子释放等功能。采用单因素分析法分别探讨了时间、硅烷偶联剂用量及温度对聚酯纤维改性整理效果的影响。结果表明:聚酯纤维最佳改性整理工艺条件为1g聚酯短纤维浸泡在含有电气石的硅烷偶联剂酸性溶液中,于50℃烘箱中静置反应6h时,电气石负载率可达1.71%。对所得改性整理纤维进行表征及性能测试,电气石粉体成功引入到了聚酯纤维表面,其远红外辐射率达0.7,负离子释放量为950ions/cm^(3)。

海藻纤维应用现状及发展

为了充分开发海藻纤维在纺织领域的应用潜力,介绍了海藻纤维的制备方式,并结合海藻纤维本体及附加性能,从纱线的可纺性、阻燃织物的开发、多功能高附加值纤维的研发以及产业化应用中存在的染色问题四方面着手,总结海藻纤维的研发及其在纺织领域的应用现状。认为:海藻纤维作为一种绿色环保纤维,来源充足,应用广泛,未来有关海藻纤维的创新研发将会得到充分发展,进一步推动海藻纤维的产业化应用。

分段式远红外-热泵干燥对龙眼品质的影响

为探究分段式远红外-热泵干燥对龙眼品质的影响,本实验以单一热泵干燥为对照,研究了不同条件下分段式远红外-热泵干燥后龙眼的质构、微观结构、褐变度、色泽和糖、游离氨基酸、5-羟甲基糠醛(5-hydroxymethylfurfural,5-HMF)含量变化。结果表明:与对照组相比,分段式远红外-热泵干燥能显著降低龙眼的硬度,提高其弹性和咀嚼性(P<0.05),同时增加龙眼内部孔隙;龙眼干燥后色泽的变化主要源于L~*值的下降(变暗)和a~*值的升高(变黄),60℃远红外-热泵干燥能有效抑制龙眼褐变;糖、游离氨基酸及5-HMF含量与龙眼色泽相关,100℃远红外干燥会造成龙眼中可溶性糖和游离氨基酸含量的显著降低及5-HMF含量的显著升高(P<0.05)。本研究确证了分段式远红外-热泵干燥能有效提高干燥龙眼品质,美拉德反应是引起龙眼干燥过程中色泽变化的主要因素。

远红外线照射联合多磺酸粘多糖乳膏对血液透析的慢性肾功能衰竭患者动静脉内瘘的影响

目的:观察远红外线照射联合多磺酸粘多糖乳膏对血液透析的慢性肾功能衰竭(CRF)患者动静脉内瘘的影响。方法:选取2023年1—6月于黔西南州人民医院进行血液透析的CRF患者70例为研究对象,随机分为对照组和试验组,各35例。对照组采用多磺酸粘多糖乳膏治疗,试验组在对照组基础上加用远红外线照射治疗。比较两组透析血流量、血管内径、透析穿刺处愈合时间、血痂消失时间、并发症发生情况。结果:治疗后,两组透析血流量增多,试验组多于对照组,差异有统计学意义(P<0.05);两组血管内径增大,试验组大于对照组,差异有统计学意义(P<0.05)。试验组透析穿刺处愈合时间、血痂消失时间短于对照组,差异有统计学意义(P<0.05)。试验组并发症总发生率低于对照组,差异有统计学意义(P=0.002)。结论:远红外线照射联合多磺酸粘多糖乳膏对CRF患者动静脉内瘘保护性较好,可提高患者透析容量,扩展血管内径,促进创口恢复,降低并发症发生率。

甲基丙烯酸电气石酯-乙酸乙烯酯共聚物的制备与表征

为了合成含电气石功能聚合物,采用甲基丙烯酸酐对电气石进行表面改性,在电气石表面引入双键,制备了甲基丙烯酸电气石酯,而后与乙酸乙烯酯进行共聚反应,合成了甲基丙烯酸电气石酯-乙酸乙烯酯共聚物。通过IR、XRD、SEM等手段对其进行结构和形貌表征,结果表明,电气石粉体成功引入到共聚物中,具有优良的分散性和储存稳定性。且甲基丙烯酸电气石酯-乙酸乙烯酯共聚物成膜后具有良好的力学性能和优异的负离子释放量、远红外辐射性等性能。

高静压、短紫外波和远红外处理对α-酪蛋白氧化的影响

研究了单循环/多循环高静压(200和600 MPa)、短紫外波(11.8 W/m2)和远红外(350W)在处理5和15min后α-酪蛋白的羰基、二聚酪氨酸、巯基、二硫键和内源荧光强度的变化。结果表明,与未经处理的对照相比,不同压力和时间导致了羰基或二聚酪氨酸的增加或降低,单循环600MPa(15min)高静压使二硫键含量增加了18%;远红外5min处理没有影响羰基和二硫键含量;短紫外波使二聚酪氨酸、羰基含量和游离巯基含量分别增加了约69%~289.4%,142.6%~529.3%和6.1%~10.3%。总之,高静压、短紫外波和远红外处理后α-酪蛋白发生不同程度的氧化,且短紫外波处理使α-酪蛋白氧化现象明显。

Mathematical Overview of Hypersphere World-Universe Model

The Hypersphere World-Universe Model (WUM) provides a mathematical framework that allows calculating the primary cosmological parameters of the World which are in good agreement with the most recent measurements and observations. WUM explains the experimental data accumulated in the field of Cosmology and Astroparticle Physics over the last decades: the age of the World and critical energy density;the gravitational parameter and Hubble’s parameter;temperatures of the cosmic microwave background radiation and the peak of the far-infrared background radiation;the concentration of intergalactic plasma and time delay of Fast Radio Bursts. Additionally, the model predicts masses of dark matter particles, photons, and neutrinos;proposes new types of particle interactions (Super Weak and Extremely Weak);shows inter-connectivity of primary cosmological parameters of the World. WUM proposes to introduce a new fundamental parameter Q in the CODATA internationally recommended values. This paper is the summary of the mathematical results obtained in [1]-[4].

5D World-Universe Model. Neutrinos. The World

In this manuscript we discuss mass-varying neutrinos and propose their energy density to exceed that of baryonic and dark matter. We introduce cosmic Large Grains whose mass is about Planck mass, and their temperature is around 29 K. Large Grains are in fact Bose-Einstein condensates of proposed dineutrinos, and are responsible for the cosmic Far-Infrared Background (FIRB) radiation. The distribution of the energy density of all components of the World (protons, electrons, photons, neutrinos, and dark matter particles) is considered. We present an overview of the World- Universe Model (WUM) and pay particular attention to the self-consistent set of time-varying values of basic parameters of the World: the age and critical energy density;Newtonian parameter of gravitation and Hubble’s parameter;temperatures of the cosmic Microwave Background radiation and the peak of the cosmic FIRB radiation;Fermi coupling parameter and coupling parameters of the proposed Super-Weak and Extremely-Weak interactions. Additionally, WUM forecasts the masses of dark matter particles, axions, and neutrinos;proposes two fundamental parameters of the World: fine-structure constant α and the quantity Q which is the dimensionless value of the fifth coordinate, and three fundamental physical units: basic unit of momentum, energy density, and energy flux density. WUM suggests that all time-dependent parameters of the World are inter- connected and in fact dependent on Q. We recommend adding the quantity Q to the list of the CODATA-recommended values.

Overview of Hypersphere World-Universe Model

This paper provides an overview of the Hypersphere World-Universe Model (WUM). WUM unifies and simplifies existing cosmological models and results into a single coherent picture, and proceeds to discuss the origin, evolution, structure, ultimate fate, and primary parameters of the World. WUM explains the experimental data accumulated in the field of Cosmology and Astroparticle Physics over the last decades: the age of the world and critical energy density;the gravitational parameter and Hubble’s parameter;temperatures of the cosmic microwave background radiation and the peak of the far-infrared background radiation;gamma-ray background and cosmic neutrino background;macrostructure of the world and macroobjects structure. Additionally, the model makes predictions pertaining to masses of dark matter particles, photons, and neutrinos, proposes new types of particle interactions (Super Weak and Extremely Weak), and shows inter-connectivity of primary cosmological parameters of the world and the rise of the solar luminosity during the last 4.6 Byr. The model proposes to introduce a new fundamental parameter Q in the CODATA internationally recommended values.

World-Universe Model Predictions

In 2013, World-Universe Model (WUM) proposed a principally different way to solve the problem of Newtonian Constant of Gravitation measurement precision. WUM revealed a self-consistent set of time-varying values of Primary Cosmological parameters of the World: Gravitation parameter, Hubble’s parameter, Age of the World, Temperature of the Microwave Background Radiation, and the concentration of Intergalactic plasma. Based on the inter-connectivity of these parameters, WUM solved the Missing Baryon problem and predicted the values of the following Cosmological parameters: gravitation G, concentration of Intergalactic plasma, relative energy density of protons in the Medium, and the minimum energy of photons, which were experimentally confirmed in 2015-2018. Between 2013 and 2018, the relative standard uncertainty of G measurements decreased x6. The set of values obtained by WUM was recommended for consideration in CODATA Recommended Values of the Fundamental Physical Constants 2014.

World-Universe Model—Alternative to Big Bang Model

This manuscript provides a comparison of the Hypersphere World-Universe Model (WUM) with the prevailing Big Bang Model (BBM) of the Standard Cosmology. The performed analysis of BBM shows that the Four Pillars of the Standard Cosmology are model-dependent and not strong enough to support the model. The angular momentum problem is one of the most critical problems in BBM. Standard Cosmology cannot explain how Galaxies and Extra Solar systems obtained their substantial orbital and rotational angular momenta, and why the orbital momentum of Jupiter is considerably larger than the rotational momentum of the Sun. WUM is the only cosmological model in existence that is consistent with the Law of Conservation of Angular Momentum. To be consistent with this Fundamental Law, WUM discusses in detail the Beginning of the World. The Model introduces Dark Epoch (spanning from the Beginning of the World for 0.4 billion years) when only Dark Matter Particles (DMPs) existed, and Luminous Epoch (ever since for 13.8 billion years). Big Bang discussed in Standard Cosmology is, in our view, transition from Dark Epoch to Luminous Epoch due to Rotational Fission of Overspinning Dark Matter (DM) Supercluster’s Cores. WUM envisions Matter carried from the Universe into the World from the fourth spatial dimension by DMPs. Ordinary Matter is a byproduct of DM annihilation. WUM solves a number of physical problems in contemporary Cosmology and Astrophysics through DMPs and their interactions: Angular Momentum problem in birth and subsequent evolution of Galaxies and Extrasolar systems—how do they obtain it;Fermi Bubbles—two large structures in gamma-rays and X-rays above and below Galactic center;Diversity of Gravitationally-Rounded Objects in Solar system;some problems in Solar and Geophysics [1]. WUM reveals Inter-Connectivity of Primary Cosmological Parameters and calculates their values, which are in good agreement with the latest results of their measurements.

活血化瘀膏联合远红外线照射治疗血液透析患者动静脉内瘘皮下血肿的疗效

目的探讨活血化瘀膏联合远红外线照射治疗血液透析患者动静脉内瘘皮下血肿的疗效。方法将84例维持性血液透析动静脉内瘘穿刺发生皮下血肿同时伴疼痛患者按随机数字表法分为观察组、对照组A组、对照组B组,每组28例。观察组采用活血化瘀膏外涂联合远红外线照射治疗,对照组A组采用活血化瘀膏外涂治疗,对照组B组采用远红外线照射治疗,疗程均为10 d。比较3组治疗前后皮下血肿、疼痛程度、血流量、血管内径的变化情况。结果3组治疗后皮下血肿、疼痛程度、血流量、血管内径均较治疗前明显改善,且观察组改善程度均显著优于对照组A组、对照组B组,差异均有统计学意义(P<0.05)。结论活血化瘀膏联合远红外线照射治疗动静脉内瘘效果显著,可减轻动静脉内瘘穿刺后皮下血肿及疼痛,改善血流通畅性及血管内径。

干燥方式对百香果皮理化、功能及抗氧化特性的影响

目的:探讨干燥方式对百香果皮的影响。方法:分别采用微波真空冷冻干燥、真空冷冻干燥、热泵干燥和远红外辐射干燥处理百香果皮,并分别测定其干燥特性、复水比、色差、膳食纤维、功能特性、微观结构、总酚含量、总黄酮含量及抗氧化性等指标。结果:热泵干燥百香果皮复水比、功能特性等较差;与远红外辐射干燥相比,微波真空冷冻干燥缩短了53%的干燥时间,且微波真空冷冻干燥处理的百香果皮具有较高的复水比(7.45)、总酚含量(13.45 mg GAE/g DW)和抗氧化活性(DPPH自由基清除率为38.53%,FRAP为1.14 mmol/L);真空冷冻干燥处理的百香果皮获得了较高的持水力[(21.64±0.21)g/g]、持油力[(6.09±0.71)g/g]、溶胀性[(25.00±1.00)g/g],以及更高的总黄酮含量(7.84 mg RT/g DW);经不同方式干燥后果皮的复水比、膳食纤维、功能特性、总酚含量、总黄酮含量、抗氧化活性等存在显著性差异(P<0.05)。结论:干燥方式对百香果皮品质具有显著影响,其中微波真空冷冻干燥是较佳干燥方式。