Background Verapamil-sensitive, idiopathic left ventricular tachycardia （ILVT） with right bundle branch block configuration and left-axis deviation is known to be due to re-entry mechanism but the exact nature of re...Background Verapamil-sensitive, idiopathic left ventricular tachycardia （ILVT） with right bundle branch block configuration and left-axis deviation is known to be due to re-entry mechanism but the exact nature of reentrant circuit in ILVT is not fully elucidated. Radiofrequency （RF） ablation was applied during ventricular tachycardia （VT） and termination of the VT or abolishing the inducibility of the tachycardia was used as an endpoint for successful RF. In this study, the left posterior fascicular block in surface electrocardiogram （ECG） was used as a new endpoint of ablation to cure ILVT. Methods Electrophysiological studies and radiofrequency ablation were performed in 39 consecutive patients [30 men, 9 women; age ranging from 10 to 64 years, mean （29± 16） years] with verapamil-sensitive ILVT and structurally normal hearts. VT could be terminated by the intravenous adininistration of verapamil in all patients. The target site was the midseptum of LV where the earliest Purkinje potentials were recorded during VT. RF current was applied to the target site with or without late diastolic potential （LDP） during sinus rhythm in 37 patients and during VT in 2 patients to meet the ablation endpoint： the left posterior fascicuiar block in the surface ECG. Results Thirty-seven patients with ILVT had been treated by RF ablation during sinus rhythm and two had been treated during VT. All of them met the endpoint of the left posterior fascicuiar block. Thirty-eight cases were symptom-free without medications during the follow-up period （range from 3 to 95 months, median 17 months）. One patient developed a clinical recurrence and the left posterior fascicuiar block in surface ECG disappeared. The patient received another treatment. The endpoint was met and the procedure was successful. Conclusions The left posterior fascicuiar block in surface ECG used as an endpoint of RF ablation to treat ILVT is effective. It is important especially in those patients whose VT can not be induced or the inducible condition is unstable. The effective endpoint implied that the left posterior fascicle might be a critical part of the re-entrant circuit.展开更多
目的研究心房-分支旁路的电生理特性及射频消融治疗。方法分析4例心房-分支旁路伴房室折返性心动过速的特征及射频消融方法。结果 4例患者的房室折返性心动过速有3例消融成功。心房-分支旁路的特性包括:心动过速和快速心房刺激时心电图...目的研究心房-分支旁路的电生理特性及射频消融治疗。方法分析4例心房-分支旁路伴房室折返性心动过速的特征及射频消融方法。结果 4例患者的房室折返性心动过速有3例消融成功。心房-分支旁路的特性包括:心动过速和快速心房刺激时心电图呈类左束支阻滞图形;旁路无逆传功能,前向传导呈现递减性传导并可被 ATP 阻断;在三尖瓣环可记录到心房-分支旁路电位,在此处成功消融并出现交界性心律失常。结论标测到心房-分支旁路电位是成功地完成消融治疗的标志。展开更多
文摘Background Verapamil-sensitive, idiopathic left ventricular tachycardia （ILVT） with right bundle branch block configuration and left-axis deviation is known to be due to re-entry mechanism but the exact nature of reentrant circuit in ILVT is not fully elucidated. Radiofrequency （RF） ablation was applied during ventricular tachycardia （VT） and termination of the VT or abolishing the inducibility of the tachycardia was used as an endpoint for successful RF. In this study, the left posterior fascicular block in surface electrocardiogram （ECG） was used as a new endpoint of ablation to cure ILVT. Methods Electrophysiological studies and radiofrequency ablation were performed in 39 consecutive patients [30 men, 9 women; age ranging from 10 to 64 years, mean （29± 16） years] with verapamil-sensitive ILVT and structurally normal hearts. VT could be terminated by the intravenous adininistration of verapamil in all patients. The target site was the midseptum of LV where the earliest Purkinje potentials were recorded during VT. RF current was applied to the target site with or without late diastolic potential （LDP） during sinus rhythm in 37 patients and during VT in 2 patients to meet the ablation endpoint： the left posterior fascicuiar block in the surface ECG. Results Thirty-seven patients with ILVT had been treated by RF ablation during sinus rhythm and two had been treated during VT. All of them met the endpoint of the left posterior fascicuiar block. Thirty-eight cases were symptom-free without medications during the follow-up period （range from 3 to 95 months, median 17 months）. One patient developed a clinical recurrence and the left posterior fascicuiar block in surface ECG disappeared. The patient received another treatment. The endpoint was met and the procedure was successful. Conclusions The left posterior fascicuiar block in surface ECG used as an endpoint of RF ablation to treat ILVT is effective. It is important especially in those patients whose VT can not be induced or the inducible condition is unstable. The effective endpoint implied that the left posterior fascicle might be a critical part of the re-entrant circuit.
文摘目的研究心房-分支旁路的电生理特性及射频消融治疗。方法分析4例心房-分支旁路伴房室折返性心动过速的特征及射频消融方法。结果 4例患者的房室折返性心动过速有3例消融成功。心房-分支旁路的特性包括:心动过速和快速心房刺激时心电图呈类左束支阻滞图形;旁路无逆传功能,前向传导呈现递减性传导并可被 ATP 阻断;在三尖瓣环可记录到心房-分支旁路电位,在此处成功消融并出现交界性心律失常。结论标测到心房-分支旁路电位是成功地完成消融治疗的标志。
