In this work,we describe a new strategy for the electrochemical determination of captopril（CA） using ferrocenemonocarboxylic acid as a mediator and multiwall carbon nanotubes as sensors in aqueous solution at pH 7.0...In this work,we describe a new strategy for the electrochemical determination of captopril（CA） using ferrocenemonocarboxylic acid as a mediator and multiwall carbon nanotubes as sensors in aqueous solution at pH 7.0.The diffusion coefficient（D）,and the kinetic parameters such as electron transfer coefficient（α）.and heterogeneous rate constant（kh）,for CA were also determined using electrochemical approaches.Under the optimized conditions,the electrocatalytic oxidation peak current of captopril showed two linear dynamic ranges with a detection limit of 0.3×10^-6 mol L^-1 captopril.The linear calibration range was 0.8×10^（-6） to 65×10^-6 mol L^-1 using cyclic voltammetry.Finally,this modified electrode was also examined as a selective,simple and precise new electrochemical sensor for the determination of captopril in real samples such as drug and patient human urine.展开更多
A novel complex [Zn（FcCOO）2（2,2＇-bipy）（H2O）]2-H2O （Fc = （η^5-C5H5）Fe（η^5-CsH4）, 2,2＇-bipy = 2,2＇-bipyridine） has been synthesized and characterized by elemental analysis, IR and X-ray diffraction. It ...A novel complex [Zn（FcCOO）2（2,2＇-bipy）（H2O）]2-H2O （Fc = （η^5-C5H5）Fe（η^5-CsH4）, 2,2＇-bipy = 2,2＇-bipyridine） has been synthesized and characterized by elemental analysis, IR and X-ray diffraction. It crystallizes in monoclinic system, space group P21/c with a = 6.8187（4）, b = 21.7155（13）, c = 19.7411（12） A, a = 90, β = 97.7420（10）, γ = 90°, CtaHssFe4Zn2N4O11, Mr = 1413.28, V = 2896.4（3）A^3, Dc = 1.620 g/cm^3, Z = 2, F（000） = 1444,μ（MoKa） = 1.857 mm^-1, R = 0.0523 and wR = 0.0982 for 3219 observed reflections （I 〉 2σ（I））. Structural analysis shows that the zinc atom is coordinated with three oxygen atoms from two ferrocenemonocarboxylates and one water molecule together with two nitrogen atoms from 2,2＇-bipyridine, giving a distorted square-pyramidal coordination geometry. The complex molecules are linked to form an infinite one-dimensional chain by both intermolecular hydrogen bonds and π-π stacking interactions of the bipyridine rings.展开更多
文摘In this work,we describe a new strategy for the electrochemical determination of captopril（CA） using ferrocenemonocarboxylic acid as a mediator and multiwall carbon nanotubes as sensors in aqueous solution at pH 7.0.The diffusion coefficient（D）,and the kinetic parameters such as electron transfer coefficient（α）.and heterogeneous rate constant（kh）,for CA were also determined using electrochemical approaches.Under the optimized conditions,the electrocatalytic oxidation peak current of captopril showed two linear dynamic ranges with a detection limit of 0.3×10^-6 mol L^-1 captopril.The linear calibration range was 0.8×10^（-6） to 65×10^-6 mol L^-1 using cyclic voltammetry.Finally,this modified electrode was also examined as a selective,simple and precise new electrochemical sensor for the determination of captopril in real samples such as drug and patient human urine.
基金Project supported by the National Natural Science Foundation of China (No. 20461001) the Research Fund of Shangrao Normal College (No. 0607)
文摘A novel complex [Zn（FcCOO）2（2,2＇-bipy）（H2O）]2-H2O （Fc = （η^5-C5H5）Fe（η^5-CsH4）, 2,2＇-bipy = 2,2＇-bipyridine） has been synthesized and characterized by elemental analysis, IR and X-ray diffraction. It crystallizes in monoclinic system, space group P21/c with a = 6.8187（4）, b = 21.7155（13）, c = 19.7411（12） A, a = 90, β = 97.7420（10）, γ = 90°, CtaHssFe4Zn2N4O11, Mr = 1413.28, V = 2896.4（3）A^3, Dc = 1.620 g/cm^3, Z = 2, F（000） = 1444,μ（MoKa） = 1.857 mm^-1, R = 0.0523 and wR = 0.0982 for 3219 observed reflections （I 〉 2σ（I））. Structural analysis shows that the zinc atom is coordinated with three oxygen atoms from two ferrocenemonocarboxylates and one water molecule together with two nitrogen atoms from 2,2＇-bipyridine, giving a distorted square-pyramidal coordination geometry. The complex molecules are linked to form an infinite one-dimensional chain by both intermolecular hydrogen bonds and π-π stacking interactions of the bipyridine rings.
