A total of 26 myopic patients （52 eyes） underwent laser in situ keratomileusis. In vivo confocal microscopy revealed that most of the regenerated corneal subbasal nerve fibers in the comeal flap originated from the ...A total of 26 myopic patients （52 eyes） underwent laser in situ keratomileusis. In vivo confocal microscopy revealed that most of the regenerated corneal subbasal nerve fibers in the comeal flap originated from the stump of corneal subbasal nerve fibers outside the ablation zone and extended towards the center of the cornea in all patients. Meanwhile, new fibers were also found to directly regenerate from deep in the stroma in some cases. Approximately 94% of regenerated corneal subbasal nerve fibers （73/78 eyes） regrew vertically into the peripheral central 6-mm circle area 1 month after surgery, 78% （28/36 eyes） grew into the central 3 6 mm area at 2 months, and 23% into the central 3-mm circle area at 3 months. In addition, there was no significant difference in corneal subbasal nerve fiber regenerative capacity between the basic fibroblast growth factor group and the 20% （vN） deproteinized extract of calf blood group. The majority of corneal subbasal nerve fiber regeneration occurred from the stump of corneal subbasal nerve fibers outside the corneal flap and the remaining growth occurred deep within the stroma.展开更多
Dear Editor,Haploidentical allogeneic hematopoietic stem cell transplantation(haplo-HSCT),a curative therapy for severe aplastic anemia(SAA)patients,has been used clinically for decades.Two models,not involving ex vit...Dear Editor,Haploidentical allogeneic hematopoietic stem cell transplantation(haplo-HSCT),a curative therapy for severe aplastic anemia(SAA)patients,has been used clinically for decades.Two models,not involving ex vitro T-cell depletion,have been adopted for haplo-HSCT in patients with SAA.The first is referred to as the"Beijing protocol"(Xu et al.,2017),and comprises a conditioning regimen using busulfex(BU),cyclophosphamide(CY).展开更多
The deep integration of digital technology and the real economy is a vital engine for boosting high-quality growth of the real economy.As a result,it is necessary to investigate the effects of this integration on the ...The deep integration of digital technology and the real economy is a vital engine for boosting high-quality growth of the real economy.As a result,it is necessary to investigate the effects of this integration on the real economy.This paper develops a two-sector model that incorporates the production sector and the technology research and development sector,taking into account both the factor attribute and the technical attribute of digital technology.Digital capital,general capital,skilled labor,and unskilled labor are considered as intermediate inputs in the model.Furthermore,this paper examines the effects of two integration modes,i.e.,factor-based integration and technology-based integration,on the development of the real economy and the biased technical change from a theoretical perspective.Empirical tests are conducted to support the analysis.The findings indicate that both factor-based integration and technology-based integration contribute positively to the development of the real economy,although technology-based integration exhibits diminishing marginal effects.Heterogeneity analysis reveals that factor-based integration plays a more significant role in promoting the development of the real economy in regions with geographical advantages,low levels of human resources,high marketization levels,or low market segmentation.On the other hand,technology-based integration assumes a greater role in facilitating the development of the real economy in regions with geographical disadvantages,low costs on human resources,low marketization levels,or high market segmentation.Further analysis demonstrates that the integration of digital technology and the real economy leads to digital capital-biased technical change and skilled labor-biased technical change.Therefore,it is imperative for the public sector to encourage the expansion of both factor-based integration and technology-based integration in the real economy.Additionally,it is also important to develop a reasonable industry layout plan and enhance the skill level of workers to address the rising demand for relevant factors resulting from changes in the biased technical change.展开更多
文摘A total of 26 myopic patients （52 eyes） underwent laser in situ keratomileusis. In vivo confocal microscopy revealed that most of the regenerated corneal subbasal nerve fibers in the comeal flap originated from the stump of corneal subbasal nerve fibers outside the ablation zone and extended towards the center of the cornea in all patients. Meanwhile, new fibers were also found to directly regenerate from deep in the stroma in some cases. Approximately 94% of regenerated corneal subbasal nerve fibers （73/78 eyes） regrew vertically into the peripheral central 6-mm circle area 1 month after surgery, 78% （28/36 eyes） grew into the central 3 6 mm area at 2 months, and 23% into the central 3-mm circle area at 3 months. In addition, there was no significant difference in corneal subbasal nerve fiber regenerative capacity between the basic fibroblast growth factor group and the 20% （vN） deproteinized extract of calf blood group. The majority of corneal subbasal nerve fiber regeneration occurred from the stump of corneal subbasal nerve fibers outside the corneal flap and the remaining growth occurred deep within the stroma.
文摘Dear Editor,Haploidentical allogeneic hematopoietic stem cell transplantation(haplo-HSCT),a curative therapy for severe aplastic anemia(SAA)patients,has been used clinically for decades.Two models,not involving ex vitro T-cell depletion,have been adopted for haplo-HSCT in patients with SAA.The first is referred to as the"Beijing protocol"(Xu et al.,2017),and comprises a conditioning regimen using busulfex(BU),cyclophosphamide(CY).
基金the“Study on Appropriate Technological Selection and Driving Force Change in the Transformation and Upgrading of China's Manufacturing Industry under High-Quality Development Orientation,”a program from the National Natural Science Foundation of China(No.71973083)the“Study on Appropriate Technology Selection,New and Old Kinetic Energy Conversion and Dynamic Mechanism of Manufacturing Industry Transformation and Upgrading,”a general humanities and social sciences research program from the Ministry of Education(No.19YJA790016)the“Study on Appropriate Technology Selection and New and Old Kinetic Energy Conversion in Manufacturing Industry Transformation and Upgrading,”a general program from Shandong Provincial Natural Science Foundation(No.ZR2019MG018).
文摘The deep integration of digital technology and the real economy is a vital engine for boosting high-quality growth of the real economy.As a result,it is necessary to investigate the effects of this integration on the real economy.This paper develops a two-sector model that incorporates the production sector and the technology research and development sector,taking into account both the factor attribute and the technical attribute of digital technology.Digital capital,general capital,skilled labor,and unskilled labor are considered as intermediate inputs in the model.Furthermore,this paper examines the effects of two integration modes,i.e.,factor-based integration and technology-based integration,on the development of the real economy and the biased technical change from a theoretical perspective.Empirical tests are conducted to support the analysis.The findings indicate that both factor-based integration and technology-based integration contribute positively to the development of the real economy,although technology-based integration exhibits diminishing marginal effects.Heterogeneity analysis reveals that factor-based integration plays a more significant role in promoting the development of the real economy in regions with geographical advantages,low levels of human resources,high marketization levels,or low market segmentation.On the other hand,technology-based integration assumes a greater role in facilitating the development of the real economy in regions with geographical disadvantages,low costs on human resources,low marketization levels,or high market segmentation.Further analysis demonstrates that the integration of digital technology and the real economy leads to digital capital-biased technical change and skilled labor-biased technical change.Therefore,it is imperative for the public sector to encourage the expansion of both factor-based integration and technology-based integration in the real economy.Additionally,it is also important to develop a reasonable industry layout plan and enhance the skill level of workers to address the rising demand for relevant factors resulting from changes in the biased technical change.
