Cytokeratin-positive interstitial reticulum cells (CIRCs) are considered to represent a subset of fibroblastic reticulum cells (FBRCs) belonging to accessory dendritic cells in lymph nodes, the spleen and tonsils....Cytokeratin-positive interstitial reticulum cells (CIRCs) are considered to represent a subset of fibroblastic reticulum cells (FBRCs) belonging to accessory dendritic cells in lymph nodes, the spleen and tonsils.1-3 The tumors arising from CIRCs are so rare that they are easily misdiagnosed as tumors originating from other accessory dendritic cells, myofibroblasts or even metastatic poor-differentiated carcinomas due to their similar histomorphologic features. We report herein one new case of a CIRC tumor (CIRCT) located in the retroperitoneum and analyze the clinicopathologic characteristics, pathogenesis, treatment and prognosis by reviewing the literature.展开更多
文摘Cytokeratin-positive interstitial reticulum cells (CIRCs) are considered to represent a subset of fibroblastic reticulum cells (FBRCs) belonging to accessory dendritic cells in lymph nodes, the spleen and tonsils.1-3 The tumors arising from CIRCs are so rare that they are easily misdiagnosed as tumors originating from other accessory dendritic cells, myofibroblasts or even metastatic poor-differentiated carcinomas due to their similar histomorphologic features. We report herein one new case of a CIRC tumor (CIRCT) located in the retroperitoneum and analyze the clinicopathologic characteristics, pathogenesis, treatment and prognosis by reviewing the literature.