Tbx 4 and Tbx 5 gene expression associated with appendage development and its relationship with the absence of the pelvic fin in Pampus argenteus

The Tbx family is first known through the study of their functions in the body and limbs,and its members Tbx4 and Tbx5 genes are important factors in determining the characteristics of the appendages.Pampus argenteus is one of the important economical marine fishes widely distributed in offshore areas.Therefore,it is necessary to study the role of Tbx family genes in the deletion of pelvic fin in P.argenteus.In this study,we cloned Tbx4 and Tbx5 cDNA sequence of P.argenteus(GenBank:MH709128 and MH712458).The Western blot and real time PCR were used to detect the expressions of Tbx4 and Tbx5 in different developmental stages and tissues of P.argenteus.In addition,whole-mount in-situ hybridization was used to study the localization of Tbx4 and Tbx5 genes in different developmental stages of P.argenteus.Results show that the translation of Tbx4 mRNA was inhibited during the critical period of pelvic fin development.Among different tissues,Tbx4 protein levels were the lowest in the abdominal epithelium,and even lower than that in the pectoral fin,suggesting that the protein expression was also inhibited in the abdominal epithelium of adult P.argenteus.Therefore,the results indicated that upstream genes regulation led to the key stage-specific and low expression of Tbx4 during pelvic fin development and in the abdominal epithelium.

Semi-analytical investigation of heat transfer in a porous convective radiative moving longitudinal fin exposed to magnetic field in the presence of a shape-dependent trihybrid nanofluid

The thermal examination of a non-integer-ordered mobile fin with a magnetism in the presence of a trihybrid nanofluid(Fe_3O_4-Au-Zn-blood) is carried out. Three types of nanoparticles, each having a different shape, are considered. These shapes include spherical(Fe_3O_4), cylindrical(Au), and platelet(Zn) configurations. The combination approach is utilized to evaluate the physical and thermal characteristics of the trihybrid and hybrid nanofluids, excluding the thermal conductivity and dynamic viscosity. These two properties are inferred by means of the interpolation method based on the volume fraction of nanoparticles. The governing equation is transformed into a dimensionless form, and the Adomian decomposition Sumudu transform method(ADSTM) is adopted to solve the conundrum of a moving fin immersed in a trihybrid nanofluid. The obtained results agree well with those numerical simulation results, indicating that this research is reliable. The influence of diverse factors on the thermal overview for varying noninteger values of γ is analyzed and presented in graphical representations. Furthermore, the fluctuations in the heat transfer concerning the pertinent parameters are studied. The results show that the heat flux in the presence of the combination of spherical, cylindrical, and platelet nanoparticles is higher than that in the presence of the combination of only spherical and cylindrical nanoparticles. The temperature at the fin tip increases by 0.705 759% when the value of the Peclet number increases by 400%, while decreases by 11.825 13% when the value of the Hartman number increases by 400%.

Heat dissipation enhancement method for finned heat sink for AGV motor driver's IGBT module

With the widespread use of high-power and highly integrated insulated gate bipolar transistor(IGBT),their cooling methods have become challenging.This paper proposes a liquid cooling scheme for heavy-duty automated guided vehicle(AGV)motor driver in port environment,and improves heat dissipation by analyzing and optimizing the core component of finned heat sink.Firstly,the temperature distribution of the initial scheme is studied by using Fluent software,and the heat transfer characteristics of the finned heat sink are obtained through numerical analysis.Secondly,an orthogonal test is designed and combined with the response surface methodology to optimize the structural parameters of the finned heat sink,resulting in a 14.57%increase in the heat dissipation effect.Finally,the effectiveness of heat dissipation enhancement is verified.This work provides valuable insights into improving the heat dissipation of IGBT modules and heat sinks,and provides guidance for their future applications.

Effect of periodic heat transfer on the transient thermal behavior of a convective-radiative fully wet porous moving trapezoidal fin

A moving trapezoidal profiled convective-radiative porous longitudinal fin wetted in a single-phase fluid is considered in the current article.The periodic variation in the fin base temperature is taken into account along with the temperature sensitive thermal conductivity and convective heat transfer coefficients.The modeled problem,which is resolved into a non-linear partial differential equation(PDE),is made dimensionless and solved by employing the finite difference method(FDM).The results are displayed through graphs and discussed.The effects of amplitude,frequency of oscillation,wet nature,Peclet number,and other relevant quantities on the distribution of temperature through the fin length and with the dimensionless time are investigated.It is deciphered that the periodic heat transfer gives rise to the wavy nature of the fin thermal profile against time.The analysis is beneficial in the design of fin structures for applications like solar collectors,space/airborne applications,and refrigeration industries.

基于FINS协议的计算机与PLC以太网通信

FINS协议用于OMRON的CompoBus/D、Controller Link、Ethernet等网络以及网络之间的通信。简要介绍了FINS协议,研究了基于FINS协议实现上位机和PLC以太网通信的方法。PLC选用OMRON CP1H型机,上位机采用Visual C++6.0编程,调用FINS指令向PLC发送命令,与PLC进行信息交换。给出部分程序代码。该方法可为进一步开发PLC监控系统提供了有价值的参考。

纳米FinFET的单粒子瞬态与Fin结构的相关性研究

工艺差异引起的Fin结构变化会造成纳米FinFET器件呈现不同的电学特性,使器件的单粒子瞬态效应(SET)复杂化。基于电学特性校准的14 nm SOI标准型FinFET器件,构建了弹头型、三角型、阶梯型、半圆型及底部椭圆型等5种结构,分析了SET的表征量与Fin结构参数间的相关性,并利用灰色理论,研究了它们之间的内在关联性。结果表明,器件的收集电荷量、沉积电荷量与Fin的截面积显著相关;SET电流峰值、电子-空穴对产生率峰值及双极放大系数同时依赖于Fin的截面积和等效沟道宽度,且对等效沟道宽度的依赖性更强。

FinFET芯片TEM样品制备及避免窗帘效应方法

制备高质量纳米尺度芯片透射电子显微镜(TEM)样品对于探索半导体器件结构设计、材料分布与芯片性能之间的关系具有重要的意义。使用聚焦离子束(FIB)/扫描电子显微镜(SEM)双束系统制备14 nm鳍式场效应晶体管(FinFET)截面TEM样品,制备过程中从技术角度提出了两种自下而上制样方案来抑制窗帘效应。为扩大样品的可表征视场范围,在避免样品弯曲的前提下,提出了一种薄片提取方法。结果表明,离子束流越大,窗帘效应越严重,自下而上方法能有效规避窗帘效应;离子束电压30 kV时采用清洗截面(CCS)模式、5 kV/2 kV时采用矩形模式,样品台倾斜补偿角度为1.5°~3.5°,进行交叉减薄,且最终铣削长度控制在1μm时减薄效果最好;新的薄片提取方法改变了样品的铣削方向,在避免窗帘效应破坏感兴趣结构和样品弯曲的前提下,将样品的可表征视场范围扩大了5倍。研究结果对优化TEM样品制备方法以及芯片失效分析提供了参考。

基于拓扑优化的车用功率模块Pin-Fin设计方法

集成Pin-Fin散热器可以降低功率模块的结-流热阻,是车用电机控制器热管理的发展趋势。然而,传统参数设计方法无法定量表征Pin-Fin的形貌结构,设计自由度低、设计效果欠佳,难以实现Pin-Fin的热-流协同设计。基于变密度拓扑优化方法,该文提出一种Pin-Fin形貌结构的设计方法,建立Pin-Fin设计的变密度拓扑优化模型,分析模型参数对优化结果和收敛性的影响规律,形成以结-流热阻和冷却液压降为目标的协同优化方法,探索Pin-Fin结构的热-流耦合规律和强化换热方法,得到最优的Pin-Fin散热器形貌结构,搭建变流器实验平台和车用电机控制器样机,对标商业化圆形Pin-Fin结构,以及三角形、菱形和水滴形等其他形貌结构,计及母线电压、负荷电流和冷却液流量的影响,实验结果验证了所提模型方法的可行性和有效性。实验结果表明:基于拓扑优化方法设计的Pin-Fin结构,与传统结构相比可以降低12%的结-流热阻,消除了多芯片结温差异的80%,为车用功率模块和电机控制器研究提供新的思路。

Finned Zn-MFI zeolite encapsulated noble metal nanoparticle catalysts for the oxidative dehydrogenation of propane with carbon dioxide

Oxidative dehydrogenation of propane with carbon dioxide(CO_(2)-ODP)characterizes the tandem dehydrogenation of propane to propylene with the reduction of the greenhouse gas of CO_(2)to valuable CO.However,the existing catalyst is limited due to the poor activity and stability,which hinders its industrialization.Herein,we design the finned Zn-MFI zeolite encapsulated noble metal nanoparticles(NPs)as bifunctional catalysts(NPs@Zn-MFI)for CO_(2)-ODP.Characterization results reveal that the Zn2+species are coordinated with the MFI zeolite matrix as isolated cations and the NPs of Pt,Rh,or Rh Pt are highly dispersed in the zeolite crystals.The isolated Zn2+cations are very effective for activating the propane and the small NPs are favorable for activating the CO_(2),which synergistically promote the selective transformation of propane and CO_(2)to propylene and CO.As a result,the optimal 0.25%Rh0.50%Pt@Zn-MFI catalyst shows the best propylene yield,satisfactory CO_(2)conversion,and long-term stability.Moreover,considering the tunable synergetic effects between the isolated cations and NPs,the developed approach offers a general guideline to design more efficient CO_(2)-ODP catalysts,which is validated by the improved performance of the bifunctional catalysts via simply substituting Sn4+cations for Zn2+cations in the MFI zeolite matrix.

Effect of temperature on heavy ion-induced single event transient on 16-nm FinFET inverter chains

The variations of single event transient(SET)pulse width of high-LET heavy ion irradiation in 16-nm-thick bulk silicon fin field-effect transistor(Fin FET)inverter chains with different driven strengths are measured at different temperatures.Three-dimensional(3D)technology computer-aided design simulations are carried out to study the SET pulse width and saturation current varying with temperature.Experimental and simulation results indicate that the increase in temperature will enhance the parasitic bipolar effect of bulk Fin FET technology,resulting in the increase of SET pulse width.On the other hand,the increase of inverter driven strength will change the layout topology,which has a complex influence on the SET temperature effects of Fin FET inverter chains.The experimental and simulation results show that the device with the strongest driven strength has the least dependence on temperature.

First Recorded Account of a White Shark Agonistic Pectoral Fin Depression Behavior at Guadalupe Island, Mexico

An agonistic display by a white shark was observed and photographed during a cage dive at Guadalupe Island in November 2015. Exhibiting exaggerated pectoral fin depression, agonistic behaviors have been previously observed and described in several shark species. This account may be the first record of a white shark in close proximity to a caged diver, exhibiting strong pectoral fin depression significantly dipped, in the mid-agonistic display. Such displays should be considered as aggressive and potentially life-threatening by those using the ocean for recreational or professional purposes.

Localized Theoretical Analysis of Thermal Performance of Individually Finned Heat Pipe Heat Exchanger for Air Conditioning with Freon R404A as Working Fluid

This work contributes to the improvement of energy-saving in air conditioning systems. The objective is to apply the thermal efficiency of heat exchangers for localized determination of the thermal performance of heat exchangers with individually finned heat pipes. The fundamental parameters used for performance analysis were the number of fins per heat pipe, the number of heat pipes, the inlet temperatures, and the flow rates of hot and cold fluids. The heat exchanger under analysis uses Freon 404A as a working fluid in an air conditioning system for cooling in the Evaporator and energy recovery in the Condenser. The theoretical model is localized and applied individually to the Evaporator, Condenser, and heat exchanger regions. The results obtained through the simulation are compared with experimental results that use a global approach for the heat exchanger. The thermal quantities obtained through the theoretical model in the mentioned regions are air velocity, Nusselt number, thermal effectiveness, heat transfer rate, and outlet temperature. The comparisons made with global experimental results are in excellent agreement, demonstrating that the localized theoretical approach developed is consistent and can be used as a comprehensive analysis tool for heat exchangers using heat pipes.

基于FINS协议的Controller Link网监控系统设计

Controller Link(CLK)网是OMRON开发的一种应用广泛的工厂自动化(FA)网络,其节点为可编程序控制器(PLC)和计算机,FINS是OMRON FA网络的通信协议。CLK网可以实现节点间的数据链接及信息通信功能。在工程应用中,要求在计算机节点上监控网络中的各个PLC节点。该文利用Visual C++6.0设计了基于FINS协议的CLK网监控系统,并成功地用于城市污水处理系统的实时监控。

Localized Theoretical Analysis of Thermal Performance of Individually Finned Heat Pipe Heat Exchanger for Air Conditioning with Freon R404A as Working Fluid

This work contributes to the improvement of energy-saving in air conditioning systems. The objective is to apply the thermal efficiency of heat exchangers for localized determination of the thermal performance of heat exchangers with individually finned heat pipes. The fundamental parameters used for performance analysis were the number of fins per heat pipe, the number of heat pipes, the inlet temperatures, and the flow rates of hot and cold fluids. The heat exchanger under analysis uses Freon 404A as a working fluid in an air conditioning system for cooling in the Evaporator and energy recovery in the Condenser. The theoretical model is localized and applied individually to the Evaporator, Condenser, and heat exchanger regions. The results obtained through the simulation are compared with experimental results that use a global approach for the heat exchanger. The thermal quantities obtained through the theoretical model in the mentioned regions are air velocity, Nusselt number, thermal effectiveness, heat transfer rate, and outlet temperature. The comparisons made with global experimental results are in excellent agreement, demonstrating that the localized theoretical approach developed is consistent and can be used as a comprehensive analysis tool for heat exchangers using heat pipes.

NPHS1基因Fin-minor突变致中国先天性肾病综合征2例报道并文献复习

目的总结2例先天性肾病综合征芬兰型NPHS1基因Fin-minor突变患儿临床资料,提高对该病的认识。方法报道2例先天性肾病综合征患儿的临床特点。对可能致病基因NPHS1、NPHS2、PLCε1、LAMB2、COQ2和LMX1B外显子和WT1基因第8、9外显子,以及外显子相邻附近区域进行直接测序。对该家系相关成员进行NPHS1基因外显子及附近调控区域直接测序,分析突变位点,并文献综述。结果 2例患儿均于出生后1个月内起病,临床表现为肾病综合征。血清病原学检查均为阴性。家系调查未发现家族中有类似疾病的成员。NPHS1、NPHS2、PLCε1、LAMB2、COQ2、LMX1B和WT1基因分析发现,2例患儿存在双NPHS1基因杂合突变,未发现其他基因有致病性突变。1例患儿为NPHS1基因的p.R1109X(c.3325C>T,Fin-minor)和IVS26DS-2A>T杂合突变,IVS26DS-2A>T剪切突变为首次报道,其父亲携带IVS26DS-2A>T,其母亲携带p.R1109X。1例患儿为NPHS1基因的p.R1109X(c.3325C>T)和p.A1160X(c.3478C>T)杂合突变,其母亲携带p.R1109X突变,未发现p.A1160X突变,其父亲拒绝行NPHS1基因分析。以上发现的突变在100例正常人群中未发现。结论中国先天性肾病综合征儿童不仅有NPHS1基因突变,而且有经典的Fin-minor突变,为国内首报。本研究新发现的IVS26DS-2A>T剪切突变丰富了NPHS1基因突变谱。

Enhancement of natural convection heat transfer from a fin by triangular perforation of bases parallel and toward its tip

This study examines the heat transfer enhancement from a horizontal rectangular fin embedded with triangular perforations （their bases parallel and toward the fin tip） under natural convection. The fin＇s heat dissipation rate is compared to that of an equivalent solid one. The parameters considered are geometrical dimensions and thermal properties of the fin and the perforations. The gain in the heat transfer enhancement and the fin weight reduction due to the perforations are considered. The study shows that the heat dissipation from the perforated fin for a certain range of triangular perforation dimensions and spaces between perforations result in improvement in the heat transfer over the equivalent solid fin. The heat transfer enhancement of the perforated fin increases as the fin thermal conductivity and its thickness are increased.

Wind Tunnel Experimental Investigation on the Aerodynamic Characteristics of the Multifin Rockets and Missiles

The transonic-supersonic wind tunnel experiment on the aerodynamics of the rockets and missiles that have four, six, eight flat or wrap-around fins is introduced. The experimental results show, while M∞〈2.0, with the increase of the fins＇number, the derivative of lift coefficient is increasing, the pressure center is shifting backwards, and the longitudinal static stability is augmenting. On the contrary, while the Mach number exceeds a certain supersonic value, the aerodynamic effectiveness of the eight-fin missiles would be lower than that of the six-fin missiles. For the low speed short-range missiles, by adopting six, eight or ten flat fins configuration, the lift effectiveness can be greatly increased, the pressure center can be shifted backwards, the static and dynamic stability can be obviously enhanced. For the high speed long-range large rockets and missiles launched from multi-tube launcher, the configuration adopting more than six fins can not be useful for increasing the stability but would make the rolling rate instable during the flight.

Lift fin stabilizers based on data fusion with wavelet denoising technology

Fin stabilizers with fin-lift feedback control can shield the mapping error of calculation between the fin angle and fin lift force,which is in the fin stabilizer with fin-angle feedback control.In practice,there are some technical difficulties in lift fin stabilizers,such as lift force detection and lift force sensor installation,so it cannot achieve the good antirolling performance.Therefore,a fin stabilizer system with fin-lift/fin-angle integrated control is brought forward.Data fusion based on wavelet denoising technology is employed in the system,which combines lift with fin angle local information from two sensors with different frequency ranges in order to eliminate redundant and contradictory information,and using complementary information to obtain the relative integrity of the lift force signal.The system model is established in this paper,and the fusion signal and the antirolling performance of this model are simulated respectively.The result shows that the control system can meet the antirolling need in different sea situations.

14 nm pFinFET 器件抗单粒子辐射的加固方法

为探究先进互补金属氧化物半导体(CMOS)工艺在空间应用中的可靠性问题,研究14 nm工艺下P型沟道鳍式场效应晶体管(pFinFET)器件中的抗单粒子瞬态(SET)加固策略。通过在器件中插入平行于鳍方向的重掺杂N型沟槽(Ntie)和P型沟槽(Ptie)来减缓SET的影响。三维TCAD仿真结果表明:加固之后器件的抗SET特性和沟槽本身的偏置条件相关。当重掺杂沟槽处于零偏状态时,抗辐射加固的性能最好,SET脉冲宽度降低程度可达40%左右;然而,当处于反偏状态时,由于特殊的电荷收集过程的存在,使得SET脉冲幅度反而会明显增大,脉冲宽度减小程度并不明显。此外,还研究沟槽面积、间距及掺杂浓度对pFinFET中的SET脉冲宽度的影响,得到提高抗SET效果的加固方法。

FinFET纳电子学与量子芯片的新进展

综述了后摩尔时代中两大发展热点:鳍式场效应晶体管(FinFET)纳电子学和基于量子计算新算法的量子芯片的发展历程和近两年的最新进展。在FinFET纳电子学领域,综述并分析了当今Si基互补金属氧化物半导体(CMOS)集成电路的发展现状,包括FinFET的发展、10 nm和7 nm技术节点的量产、5 nm和3 nm技术节点的环栅场效应晶体管(GAAFET)和2 nm技术节点的负电容场效应晶体管(FET)的前瞻性技术研究以及非Si器件(InGaAs FinFET、WS2和MoS2两种2D材料的FET)的探索性研究。指出继续摩尔定律的发展将以Si基FinFET和GAAFET的技术发展为主。在量子芯片领域,综述并分析了超导、电子自旋、光子、金刚石中的氮空位中心和离子阱等五种量子比特芯片的发展历程,提高相干时间、固态化及多量子比特扩展等的技术突破,以及近几年在量子信息应用的新进展。基于Si基的纳米制造技术和新的量子计算算法的结合正加速量子计算向工程化的进展。