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Hyperbolic Tangent Function-Based Protocols for Global/Semi-Global Finite-Time Consensus of Multi-Agent Systems
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作者 Zongyu Zuo Jingchuan Tang +1 位作者 Ruiqi Ke Qing-Long Han 《IEEE/CAA Journal of Automatica Sinica》 SCIE EI CSCD 2024年第6期1381-1397,共17页
This paper investigates the problem of global/semi-global finite-time consensus for integrator-type multi-agent sys-tems.New hyperbolic tangent function-based protocols are pro-posed to achieve global and semi-global ... This paper investigates the problem of global/semi-global finite-time consensus for integrator-type multi-agent sys-tems.New hyperbolic tangent function-based protocols are pro-posed to achieve global and semi-global finite-time consensus for both single-integrator and double-integrator multi-agent systems with leaderless undirected and leader-following directed commu-nication topologies.These new protocols not only provide an explicit upper-bound estimate for the settling time,but also have a user-prescribed bounded control level.In addition,compared to some existing results based on the saturation function,the pro-posed approach considerably simplifies the protocol design and the stability analysis.Illustrative examples and an application demonstrate the effectiveness of the proposed protocols. 展开更多
关键词 consensus protocol finite-time consensus hyper-bolic tangent function multi-agent systems.
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Finite-time consensus for leader-following multi-agent systems over switching network topologies 被引量:7
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作者 孙凤兰 朱伟 《Chinese Physics B》 SCIE EI CAS CSCD 2013年第11期152-158,共7页
Finite-time consensus problem of the leader-following multi-agent system under switching network topologies is studied in this paper. Based on the graph theory, matrix theory, homogeneity with dilation, and LaSalle's... Finite-time consensus problem of the leader-following multi-agent system under switching network topologies is studied in this paper. Based on the graph theory, matrix theory, homogeneity with dilation, and LaSalle's invariance principle, the control protocol of each agent using local information is designed, and the detailed analysis of the leader- following finite-time consensus is provided. Some examples and simulation results are given to illustrate the effectiveness of the obtained theoretical results. 展开更多
关键词 finite-time consensus leader-following multi-agent system
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Finite-time consensus of heterogeneous multi-agent systems 被引量:3
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作者 朱亚锟 关新平 罗小元 《Chinese Physics B》 SCIE EI CAS CSCD 2013年第3期550-555,共6页
We investigate the finite-time consensus problem for heterogeneous multi-agent systems composed of first-order and second-order agents.A novel continuous nonlinear distributed consensus protocol is constructed,and fin... We investigate the finite-time consensus problem for heterogeneous multi-agent systems composed of first-order and second-order agents.A novel continuous nonlinear distributed consensus protocol is constructed,and finite-time consensus criteria are obtained for the heterogeneous multi-agent systems.Compared with the existing results,the stationary and kinetic consensuses of the heterogeneous multi-agent systems can be achieved in a finite time respectively.Moreover,the leader can be a first-order or a second-order integrator agent.Finally,some simulation examples are employed to verify the efficiency of the theoretical results. 展开更多
关键词 heterogeneous multi-agent system finite-time consensus nonlinear consensus protocol
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Finite-time consensus of multi-agent systems driven by hyperbolic partial differential equations via boundary control 被引量:2
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作者 Xuhui WANG Nanjing HUANG 《Applied Mathematics and Mechanics(English Edition)》 SCIE EI CSCD 2021年第12期1799-1816,共18页
The leaderless and leader-following finite-time consensus problems for multiagent systems(MASs)described by first-order linear hyperbolic partial differential equations(PDEs)are studied.The Lyapunov theorem and the un... The leaderless and leader-following finite-time consensus problems for multiagent systems(MASs)described by first-order linear hyperbolic partial differential equations(PDEs)are studied.The Lyapunov theorem and the unique solvability result for the first-order linear hyperbolic PDE are used to obtain some sufficient conditions for ensuring the finite-time consensus of the leaderless and leader-following MASs driven by first-order linear hyperbolic PDEs.Finally,two numerical examples are provided to verify the effectiveness of the proposed methods. 展开更多
关键词 finite-time consensus hyperbolic partial differential equation(PDE) leaderless multi-agent system(MAS) leader-following MAS boundary control
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Finite-time Consensus of Heterogeneous Multi-agent Systems with Linear and Nonlinear Dynamics 被引量:4
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作者 ZHU Ya-Kun GUAN Xin-Ping LUO Xiao-Yuan 《自动化学报》 EI CSCD 北大核心 2014年第11期2618-2624,共7页
关键词 非线性动力学 多智能体系统 有限时间 异构 多代理系统 平衡状态 计算结果 领导者
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Distributed Step-by-step Finite-time Consensus Design for Battery Energy Storage Devices with Droop Control 被引量:2
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作者 Yalin Zhang Yunzhong Song Shumin Fei 《CSEE Journal of Power and Energy Systems》 SCIE EI CSCD 2023年第5期1893-1904,共12页
As all generators are distributed in different areas among large scale power systems,the cooperative manipulation of the multi-generator system cannot operate well without consideration of the distance information of ... As all generators are distributed in different areas among large scale power systems,the cooperative manipulation of the multi-generator system cannot operate well without consideration of the distance information of the generators.A distributed step-by-step finite-time consensus scheme for the heterogeneous battery energy storage system(BESS)is proposed in this paper,where the coordinated consensus can come into reality within a limited time,which is appealing for the electrical engineering community.To be concrete,at first,all BESSs are classified into several clusters according to their locations,and in each cluster,there is an active leader in charge of information receiving from outside.Then,in order to coordinate the multi BESSs,five inputs,which are function oriented,were used to achieve energy level balancing,active/reactive power sharing,and the consensus of voltage and frequency of the multi BESSs.Furthermore,the frequency and voltage restoration to the nominal values of the main grid were made possible by the introduction of a virtual leader,which is actually an external leader.Compared with the centralized methods,this control scheme is entirely distributed,and each BESS only utilizes the information of its own and its neighbors.In addition,this control is robust to the load perturbation and the plug-and-play of the communication topology.Finally,some simulation experiments are executed on the modified IEEE 57-bus system to verify the suggested scheme. 展开更多
关键词 Battery energy storage system distributed cooperative control finite-time consensus multi-agent system step-by-step consensus
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Finite-Time Consensus of a Leader-Following Multi-Agent Network with Non-Identical Nonlinear Dynamics and Time-Varying Topologies 被引量:4
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作者 YU Le TU Lilan HUANG Yifan 《Wuhan University Journal of Natural Sciences》 CAS CSCD 2016年第5期438-444,共7页
In this paper, the finite-time consensus of a leader-following multi-agent network with non-identical nonlinear dynamics and time-varying topologies is investigated. All the agents, especially the leaders, have non-id... In this paper, the finite-time consensus of a leader-following multi-agent network with non-identical nonlinear dynamics and time-varying topologies is investigated. All the agents, especially the leaders, have non-identical and nonlinear dynamics. According to the algebraic graph theory, Lyapunov stability theory and Kronecker product, a control strategy strategy is established to guarantee the finite-time consensus of multi-agent network with multiple leaders. Furthermore, several numerical simulations illustrate the effectiveness and feasibility of the proposed method. 展开更多
关键词 finite-time consensus leader-following multi-agent network algebraic graph theory Lyapunov stability theory Kronecker product
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Finite-time Prescribed Performance Time-Varying Formation Control for Second-Order Multi-Agent Systems With Non-Strict Feedback Based on a Neural Network Observer 被引量:1
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作者 Chi Ma Dianbiao Dong 《IEEE/CAA Journal of Automatica Sinica》 SCIE EI CSCD 2024年第4期1039-1050,共12页
This paper studies the problem of time-varying formation control with finite-time prescribed performance for nonstrict feedback second-order multi-agent systems with unmeasured states and unknown nonlinearities.To eli... This paper studies the problem of time-varying formation control with finite-time prescribed performance for nonstrict feedback second-order multi-agent systems with unmeasured states and unknown nonlinearities.To eliminate nonlinearities,neural networks are applied to approximate the inherent dynamics of the system.In addition,due to the limitations of the actual working conditions,each follower agent can only obtain the locally measurable partial state information of the leader agent.To address this problem,a neural network state observer based on the leader state information is designed.Then,a finite-time prescribed performance adaptive output feedback control strategy is proposed by restricting the sliding mode surface to a prescribed region,which ensures that the closed-loop system has practical finite-time stability and that formation errors of the multi-agent systems converge to the prescribed performance bound in finite time.Finally,a numerical simulation is provided to demonstrate the practicality and effectiveness of the developed algorithm. 展开更多
关键词 finite-time control multi-agent systems neural network prescribed performance control time-varying formation control
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Finite-time Consensus for Multi-agent Systems via Nonlinear Control Protocols 被引量:1
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作者 Ya-Kun Zhu Xin-Ping Guan Xiao-Yuan Luo 《International Journal of Automation and computing》 EI CSCD 2013年第5期455-462,共8页
This paper investigates the fnite-time consensus problem of multi-agent systems with single and double integrator dynamics,respectively.Some novel nonlinear protocols are constructed for frst-order and second-order le... This paper investigates the fnite-time consensus problem of multi-agent systems with single and double integrator dynamics,respectively.Some novel nonlinear protocols are constructed for frst-order and second-order leader-follower multi-agent systems,respectively.Based on the fnite-time control technique,the graph theory and Lyapunov direct method,some theoretical results are proposed to ensure that the states of all the follower agents can converge to its leader agent s state in fnite time.Finally,some simulation results are presented to illustrate the efectiveness of our theoretical results. 展开更多
关键词 finite-time consensus multi-agent systems nonlinear control protocol leader-follower single and double integratordynamics
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Finite-Time Stabilization for Constrained Discrete-time Systems by Using Model Predictive Control
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作者 Bing Zhu Xiaozhuoer Yuan +1 位作者 Li Dai Zhiwen Qiang 《IEEE/CAA Journal of Automatica Sinica》 SCIE EI CSCD 2024年第7期1656-1666,共11页
In this paper, a model predictive control(MPC)framework is proposed for finite-time stabilization of linear and nonlinear discrete-time systems subject to state and control constraints. The proposed MPC framework guar... In this paper, a model predictive control(MPC)framework is proposed for finite-time stabilization of linear and nonlinear discrete-time systems subject to state and control constraints. The proposed MPC framework guarantees the finite-time convergence property by assigning the control horizon equal to the dimension of the overall system, and only penalizing the terminal cost in the optimization, where the stage costs are not penalized explicitly. A terminal inequality constraint is added to guarantee the feasibility and stability of the closed-loop system.Initial feasibility can be improved via augmentation. The finite-time convergence of the proposed MPC is proved theoretically,and is supported by simulation examples. 展开更多
关键词 CONSTRAINTS deadbeat control finite-time stabilization model predictive control(MPC)
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Bipartite consensus problems of Lurie multi-agent systems over signed graphs: A contraction approach
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作者 张晓娇 吴祥 《Chinese Physics B》 SCIE EI CAS CSCD 2024年第7期137-145,共9页
This paper examines the bipartite consensus problems for the nonlinear multi-agent systems in Lurie dynamics form with cooperative and competitive communication between different agents. Based on the contraction theor... This paper examines the bipartite consensus problems for the nonlinear multi-agent systems in Lurie dynamics form with cooperative and competitive communication between different agents. Based on the contraction theory, some new conditions for the nonlinear Lurie multi-agent systems reaching bipartite leaderless consensus and bipartite tracking consensus are presented. Compared with the traditional methods, this approach degrades the dimensions of the conditions, eliminates some restrictions of the system matrix, and extends the range of the nonlinear function. Finally, two numerical examples are provided to illustrate the efficiency of our results. 展开更多
关键词 contraction theory virtual system bipartite consensus Lurie multi-agent systems
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CRBFT:A Byzantine Fault-Tolerant Consensus Protocol Based on Collaborative Filtering Recommendation for Blockchains
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作者 Xiangyu Wu Xuehui Du +3 位作者 Qiantao Yang Aodi Liu Na Wang Wenjuan Wang 《Computers, Materials & Continua》 SCIE EI 2024年第7期1491-1519,共29页
Blockchain has been widely used in finance,the Internet of Things(IoT),supply chains,and other scenarios as a revolutionary technology.Consensus protocol plays a vital role in blockchain,which helps all participants t... Blockchain has been widely used in finance,the Internet of Things(IoT),supply chains,and other scenarios as a revolutionary technology.Consensus protocol plays a vital role in blockchain,which helps all participants to maintain the storage state consistently.However,with the improvement of network environment complexity and system scale,blockchain development is limited by the performance,security,and scalability of the consensus protocol.To address this problem,this paper introduces the collaborative filtering mechanism commonly used in the recommendation system into the Practical Byzantine Fault Tolerance(PBFT)and proposes a Byzantine fault-tolerant(BFT)consensus protocol based on collaborative filtering recommendation(CRBFT).Specifically,an improved collaborative filtering recommendation method is designed to use the similarity between a node’s recommendation opinions and those of the recommender as a basis for determining whether to adopt the recommendation opinions.This can amplify the recommendation voice of good nodes,weaken the impact of cunningmalicious nodes on the trust value calculation,andmake the calculated resultsmore accurate.In addition,the nodes are given voting power according to their trust value,and a weight randomelection algorithm is designed and implemented to reduce the risk of attack.The experimental results show that CRBFT can effectively eliminate various malicious nodes and improve the performance of blockchain systems in complex network environments,and the feasibility of CRBFT is also proven by theoretical analysis. 展开更多
关键词 Blockchain consensus byzantine fault-tolerant collaborative filtering TRUST
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Evidence-based expert consensus on clinical management of safety of Bruton’s tyrosine kinase inhibitors(2024)
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作者 Zaiwei Song Dan Jiang +19 位作者 Lingling Yu Yixuan Chen Daobin Zhou Yue Li Depei Wu Lingli Zhang Liyan Miao Jun Ma Jun Zhu Hongmei Jing Rongsheng Zhao the Steering Committee,the Consensus Panel and the Evidence Synthesis Group Evidence-based Pharmacy Professional Committee of Chinese Pharmaceutical Association(CPA) Hospital Pharmacy Professional Committee of Chinese Pharmaceutical Association(CPA) Division of Therapeutic Drug Monitoring of Chinese Pharmacological Society(CPS) Expert Committee on Lymphoma of Chinese Society of Clinical Oncology(CSCO) Expert Committee on Leukemia of Chinese Society of Clinical Oncology(CSCO) Society of Integrative Cardio-Oncology of China Anti-Cancer Association(CACA) Chinese Society of Hematology of Chinese Medical Association(CMA) Hospital Pharmacy Professional Committee of Cross-Straits Medicine Exchange Association(SMEA) 《Chinese Journal of Cancer Research》 SCIE CAS CSCD 2024年第3期240-256,共17页
Bruton’s tyrosine kinase inhibitors(BTKis)have revolutionized the treatment of B-cell lymphomas.However,safety issues related to the use of BTKis may hinder treatment continuity and further affect clinical efficacy.A... Bruton’s tyrosine kinase inhibitors(BTKis)have revolutionized the treatment of B-cell lymphomas.However,safety issues related to the use of BTKis may hinder treatment continuity and further affect clinical efficacy.A comprehensive and systematic expert consensus from a pharmacological perspective is lacking for safety issues associated with BTKi treatment.A multidisciplinary consensus working group was established,comprising 35 members from the fields of hematology,cardiovascular disease,cardio-oncology,clinical pharmacy,and evidencebased medicine.This evidence-based expert consensus was formulated using an evidence-based approach and the Delphi method.The Joanna Briggs Institute Critical Appraisal(JBI)tool and Grading of Recommendations Assessment,Development,and Evaluation(GRADE)approach were used to rate the quality of evidence and grade the strength of recommendations,respectively.This consensus provides practical recommendations for BTKis medication based on nine aspects within three domains,including the management of common adverse drug events such as bleeding,cardiovascular events,and hematological toxicity,as well as the management of drug-drug interactions and guidance for special populations.This multidisciplinary expert consensus could contribute to promoting a multi-dimensional,comprehensive and standardized management of BTKis. 展开更多
关键词 consensus BTK inhibitors SAFETY adverse drug events drug-drug interactions
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Finite-time decentralized event-triggered state estimation for coupled neural networks under unreliable Markovian network against mixed cyberattacks
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作者 Xiulin Wang Youzhi Cai Feng Li 《Chinese Physics B》 SCIE EI CAS CSCD 2024年第11期175-183,共9页
This article investigates the issue of finite-time state estimation in coupled neural networks under random mixed cyberattacks,in which the Markov process is used to model the mixed cyberattacks.To optimize the utiliz... This article investigates the issue of finite-time state estimation in coupled neural networks under random mixed cyberattacks,in which the Markov process is used to model the mixed cyberattacks.To optimize the utilization of channel resources,a decentralized event-triggered mechanism is adopted during the information transmission.By establishing the augmentation system and constructing the Lyapunov function,sufficient conditions are obtained for the system to be finite-time bounded and satisfy the H∞ performance index.Then,under these conditions,a suitable state estimator gain is obtained.Finally,the feasibility of the method is verified by a given illustrative example. 展开更多
关键词 Markov jump systems coupled neural networks decentralized event-triggered mechanism finite-time state estimation
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Designing Proportional-Integral Consensus Protocols for Second-Order Multi-Agent Systems Using Delayed and Memorized State Information
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作者 Honghai Wang Qing-Long Han 《IEEE/CAA Journal of Automatica Sinica》 SCIE EI CSCD 2024年第4期878-892,共15页
This paper is concerned with consensus of a secondorder linear time-invariant multi-agent system in the situation that there exists a communication delay among the agents in the network.A proportional-integral consens... This paper is concerned with consensus of a secondorder linear time-invariant multi-agent system in the situation that there exists a communication delay among the agents in the network.A proportional-integral consensus protocol is designed by using delayed and memorized state information.Under the proportional-integral consensus protocol,the consensus problem of the multi-agent system is transformed into the problem of asymptotic stability of the corresponding linear time-invariant time-delay system.Note that the location of the eigenvalues of the corresponding characteristic function of the linear time-invariant time-delay system not only determines the stability of the system,but also plays a critical role in the dynamic performance of the system.In this paper,based on recent results on the distribution of roots of quasi-polynomials,several necessary conditions for Hurwitz stability for a class of quasi-polynomials are first derived.Then allowable regions of consensus protocol parameters are estimated.Some necessary and sufficient conditions for determining effective protocol parameters are provided.The designed protocol can achieve consensus and improve the dynamic performance of the second-order multi-agent system.Moreover,the effects of delays on consensus of systems of harmonic oscillators/double integrators under proportional-integral consensus protocols are investigated.Furthermore,some results on proportional-integral consensus are derived for a class of high-order linear time-invariant multi-agent systems. 展开更多
关键词 consensus protocol Hurwitz stability multi-agent systems quasi-polynomials time delay
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A Bitcoin Address Multi-Classification Mechanism Based on Bipartite Graph-Based Maximization Consensus
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作者 Lejun Zhang Junjie Zhang +4 位作者 Kentaroh Toyoda Yuan Liu Jing Qiu Zhihong Tian Ran Guo 《Computer Modeling in Engineering & Sciences》 SCIE EI 2024年第4期783-800,共18页
Bitcoin is widely used as the most classic electronic currency for various electronic services such as exchanges,gambling,marketplaces,and also scams such as high-yield investment projects.Identifying the services ope... Bitcoin is widely used as the most classic electronic currency for various electronic services such as exchanges,gambling,marketplaces,and also scams such as high-yield investment projects.Identifying the services operated by a Bitcoin address can help determine the risk level of that address and build an alert model accordingly.Feature engineering can also be used to flesh out labeled addresses and to analyze the current state of Bitcoin in a small way.In this paper,we address the problem of identifying multiple classes of Bitcoin services,and for the poor classification of individual addresses that do not have significant features,we propose a Bitcoin address identification scheme based on joint multi-model prediction using the mapping relationship between addresses and entities.The innovation of the method is to(1)Extract as many valuable features as possible when an address is given to facilitate the multi-class service identification task.(2)Unlike the general supervised model approach,this paper proposes a joint prediction scheme for multiple learners based on address-entity mapping relationships.Specifically,after obtaining the overall features,the address classification and entity clustering tasks are performed separately,and the results are subjected to graph-basedmaximization consensus.The final result ismade to baseline the individual address classification results while satisfying the constraint of having similarly behaving entities as far as possible.By testing and evaluating over 26,000 Bitcoin addresses,our feature extraction method captures more useful features.In addition,the combined multi-learner model obtained results that exceeded the baseline classifier reaching an accuracy of 77.4%. 展开更多
关键词 Bitcoin multi-service classification graph maximization consensus data security
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Fully Completed Spherical Fuzzy Approach-Based Z Numbers(PHIModel)for Enhanced Group Expert Consensus
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作者 Phi-Hung Nguyen 《Computers, Materials & Continua》 SCIE EI 2024年第7期1655-1675,共21页
This study aims to establish an expert consensus and enhance the efficacy of decision-making processes by integrating Spherical Fuzzy Sets(SFSs)and Z-Numbers(SFZs).A novel group expert consensus technique,the PHImodel... This study aims to establish an expert consensus and enhance the efficacy of decision-making processes by integrating Spherical Fuzzy Sets(SFSs)and Z-Numbers(SFZs).A novel group expert consensus technique,the PHImodel,is developed to address the inherent limitations of both SFSs and the traditional Delphi technique,particularly in uncertain,complex scenarios.In such contexts,the accuracy of expert knowledge and the confidence in their judgments are pivotal considerations.This study provides the fundamental operational principles and aggregation operators associated with SFSs and Z-numbers,encompassing weighted geometric and arithmetic operators alongside fully developed operators tailored for SFZs numbers.Subsequently,a case study and comparative analysis are conducted to illustrate the practicality and effectiveness of the proposed operators and methodologies.Integrating the PHI model with SFZs numbers represents a significant advancement in decision-making frameworks reliant on expert input.Further,this combination serves as a comprehensive tool for decision-makers,enabling them to achieve heightened levels of consensus while concurrently assessing the reliability of expert contributions.The case study results demonstrate the PHI model’s utility in resolving complex decision-making scenarios,showcasing its ability to improve consensus-building processes and enhance decision outcomes.Additionally,the comparative analysis highlights the superiority of the integrated approach over traditional methodologies,underscoring its potential to revolutionize decision-making practices in uncertain environments. 展开更多
关键词 Spherical fuzzy sets Delphi method Z-numbers expert consensus PHI model uncertainty
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Transperineal laser ablation of the prostate as a treatment for benign prostatic hyperplasia and prostate cancer: The results of a Delphi consensus project
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作者 Andrea Cocci Marta Pezzoli +35 位作者 Fernando Bianco Franco Blefari Pierluigi Bove Francois Cornud Gaetano De Rienzo Paolo Destefanis Danilo Di Trapani Alessandro Giacobbe Luca Giovanessi Antonino Laganà Giovanni Lughezzani Guglielmo Manenti Gianluca Muto Gianluigi Patelli Novello Pinzi Stefano Regusci Giorgio I.Russo Juan I.M.Salamanca Matteo Salvi Luigi Silvestri Fabrizio Verweij Eric Walser Riccardo GBertolo Valerio Iacovelli Alessandro Bertaccini Debora Marchiori Hugo Davila Pasquale Ditonno Paolo Gontero Gennaro Iapicca Theo M De Reijke Vito Ricapito Pierluca Pellegrini Andrea Minervini Sergio Serni Francesco Sessa 《Asian Journal of Urology》 CSCD 2024年第2期271-279,共9页
Objective: To evaluate transperineal laser ablation (TPLA) with Echolaser® (Echolaser® TPLA, Elesta S.p.A., Calenzano, Italy) as a treatment for benign prostatic hyperplasia (BPH) and prostate cancer (PCa) u... Objective: To evaluate transperineal laser ablation (TPLA) with Echolaser® (Echolaser® TPLA, Elesta S.p.A., Calenzano, Italy) as a treatment for benign prostatic hyperplasia (BPH) and prostate cancer (PCa) using the Delphi consensus method.Methods: Italian and international experts on BPH and PCa participated in a collaborative consensus project. During two rounds, they expressed their opinions on Echolaser® TPLA for the treatment of BPH and PCa answering online questionnaires on indications, methodology, and potential complications of this technology. Level of agreement or disagreement to reach consensus was set at 75%. If the consensus was not achieved, questions were modified after each round. A final round was performed during an online meeting, in which results were discussed and finalized.Results: Thirty-two out of forty invited experts participated and consensus was reached on all topics. Agreement was achieved on recommending Echolaser® TPLA as a treatment of BPH in patients with ample range of prostate volume, from <40 mL (80%) to >80 mL (80%), comorbidities (100%), antiplatelet or anticoagulant treatment (96%), indwelling catheter (77%), and strong will of preserving ejaculatory function (100%). Majority of respondents agreed that Echolaser® TPLA is a potential option for the treatment of localized PCa (78%) and recommended it for low-risk PCa (90%). During the final round, experts concluded that it can be used for intermediate-risk PCa and it should be proposed as an effective alternative to radical prostatectomy for patients with strong will of avoiding urinary incontinence and sexual dysfunction. Almost all participants agreed that the transperineal approach of this organ-sparing technique is safer than transrectal and transurethral approaches typical of other techniques (97% of agreement among experts). Pre-procedural assessment, technical aspects, post-procedural catheterization, pharmacological therapy, and expected outcomes were discussed, leading to statements and recommendations.Conclusion: Echolaser® TPLA is a safe and effective procedure that treats BPH and localized PCa with satisfactory functional and sexual outcomes. 展开更多
关键词 Transperineal laser ablation Prostatecancer Benignprostatic hyperplasia Delphi consensus
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Overlapping approach Proton Pump Inhibitors/Nux vomica-Heel as new intervention for gastro-esophageal reflux management:Delphi consensus study
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作者 Edda Battaglia Luciano Bertolusso +2 位作者 Marco Del Prete Marco Monzani Marco Astegiano 《World Journal of Gastroenterology》 SCIE CAS 2024年第18期2467-2478,共12页
BACKGROUND Gastro-esophageal reflux disease(GERD)may affect the upper digestive tract;up to 20%of population in Western nations are affected by GERD.Antacids,histamine H2-receptor antagonists,and Proton Pump Inhibitor... BACKGROUND Gastro-esophageal reflux disease(GERD)may affect the upper digestive tract;up to 20%of population in Western nations are affected by GERD.Antacids,histamine H2-receptor antagonists,and Proton Pump Inhibitors(PPIs)are considered the referring medications for GERD.Nevertheless,PPIs must be managed carefully because their use,especially chronic,could be linked with some adverse effects.An effective and safe alternative pharmacological tool for GERD is needed.After the identification of potentially new medications to flank PPIs,it is mandatory to revise and improve good clinical practices even through a consensus process.AIM To optimize diagnosis and treatment guidelines for GERD through a consensus based on Delphi method.METHODS The availability of clinical studies describing the action of the multicomponent/multitarget medication Nux vomica-Heel,subject of the consensus,is the basic prerequisite for the consensus itself.A modified Delphi process was used to reach a consensus among a panel of Italian GERD specialists on the overlapping approach PPIs/Nux vomica-Heel as a new intervention model for the management of GERD.The Voting Consensus group was composed of 49 Italian Medical Doctors with different specializations:Gastroenterology,otolaryngology,geriatrics,and general medicine.A scientific committee analyzed the literature,determined areas that required investigation(in agreement with the multiple-choice questionnaire results),and identified two topics of interest:(1)GERD disease;and(2)GERD treatment.Statements for each of these topics were then formulated and validated.The Delphi process involved two rounds of questioning submitted to the panel experts using an online platform.RESULTS According to their routinary GERD practice and current clinical evidence,the panel members provided feedback to each questionnaire statement.The experts evaluated 15 statements and reached consensus on all 15.The statements regarding the GERD disease showed high levels of agreement,with consensus ranging from 70%to 92%.The statements regarding the GERD treatment also showed very high levels of agreement,with consensus ranging from 90%to 100%.This Delphi process was able to reach consensus among physicians in relevant aspects of GERD management,such as the adoption of a new approach to treat patients with GERD based on the overlapping between PPIs and Nux vomica-Heel.The consensus was unanimous among the physicians with different specializations,underlying the uniqueness of the agreement reached to identify in the overlapping approach between PPIs and Nux vomica-Heel a new intervention model for GERD management.The results support that an effective approach to deprescribe PPIs through a progressive decalage timetable(reducing PPIs administration to as-needed use),should be considered.CONCLUSION Nux vomica-Heel appears to be a valid opportunity for GERD treatment to favor the deprescription of PPIs and to maintain low disease activity together with the symptomatology remission. 展开更多
关键词 Gastro-esophageal reflux disease Proton Pump Inhibitors consensus Nux vomica-Heel OVERLAPPING Decalage
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Mean nocturnal baseline impedance in gastro-esophageal reflux disease diagnosis:Should we strictly follow the Lyon 2 Consensus?
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作者 Theodoros A Voulgaris Georgios P Karamanolis 《World Journal of Gastroenterology》 SCIE CAS 2024年第26期3253-3256,共4页
Clinical practice guidelines drive clinical practice and clinicians rely to them when trying to answer their most common questions.One of the most important position papers in the field of gastro-esophageal reflux dis... Clinical practice guidelines drive clinical practice and clinicians rely to them when trying to answer their most common questions.One of the most important position papers in the field of gastro-esophageal reflux disease(GERD)is the one produced by the Lyon Consensus.Recently an updated second version has been released.Mean nocturnal baseline impedance(MNBI)was proposed by the first Consensus to act as supportive evidence for GERD diagnosis.Originally a cut-off of 2292 Ohms was proposed,a value revised in the second edition.The updated Consensus recommended that an MNBI<1500 Ohms strongly suggests GERD while a value>2500 Ohms can be used to refute GERD.The proposed cut-offs move in the correct direction by diminishing the original cut-off,nevertheless they arise from a study of normal subjects where cut-offs were provided by measuring the mean value±2SD and not in symptomatic patients.However,data exist that even symptomatic patients with inconclusive disease or reflux hypersensitivity(RH)show lower MNBI values in comparison to normal subjects or patients with functional heartburn(FH).Moreover,according to the data,MNBI,even among symptomatic patients,is affected by age and body mass index.Also,various studies have proposed different cut-offs by using receiver operating characteristic curve analysis even lower than the one proposed.Finally,no information is given for patients submitted to on-proton pump inhibitors pH-impedance studies even if new and extremely important data now exist.Therefore,even if MNBI is an extremely important tool when trying to approach patients with reflux symptoms and could distinguish conclusive GERD from RH or FH,its values should be interpreted with caution. 展开更多
关键词 Mean nocturnal baseline impedance Gastro-esophageal reflux disease Lyon 2 consensus pH-impedance DIAGNOSIS
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