The evolution of coronary intervention techniques and equipment has led to more sophisticated procedures for the treatment of highly complex lesions.However,as a result,the risk of complications has increased,which ar...The evolution of coronary intervention techniques and equipment has led to more sophisticated procedures for the treatment of highly complex lesions.However,as a result,the risk of complications has increased,which are mostly iatrogenic and often include equipment failure.Stent dislodgement warrants vigilance for the early diagnosis and a stepwise management approach is required to either expand or retrieve the lost stent.In the era of bioresorbable scaffolds that are not radiopaque,increased caution is required.Intravascular imaging may assist in detecting the lost scaffold in cases of no visibility fluoroscopically.Adequate lesion preparation is the key to minimizing the possibility of equipment loss;however,in the case that it occurs,commercially available and improvised devices and techniques may be applied.展开更多
Contrast-induced acute kidney injury(CI-AKI)is a major concern in clinical practice,particularly among high-risk patients with preexisting renal and cardiovascular conditions.Although periprocedural hydration has long...Contrast-induced acute kidney injury(CI-AKI)is a major concern in clinical practice,particularly among high-risk patients with preexisting renal and cardiovascular conditions.Although periprocedural hydration has long been the primary approach for CI-AKI prevention,recent advancements have led to the development of novel approaches such as RenalGuard and contrast removal systems.This editorial explores these emerging approaches and highlights their potential for enhancing CI-AKI prevention.By incorporating the latest evidence into clinical practice,health-care professionals can more effectively maintain renal function and improve outcomes for patients undergoing contrast-enhanced procedures.展开更多
This study concerns the heat transfer processes during ice accretion on wires. The steady state heat balance equation assumed to describe the thermodynamics at the surface of a current heated wire subjected to icing i...This study concerns the heat transfer processes during ice accretion on wires. The steady state heat balance equation assumed to describe the thermodynamics at the surface of a current heated wire subjected to icing is obtained by analyzing and computing each terms of heat flux. The surface temperature of wire is derived from the heat balance equation, which gives out a proposed estimation of the current intensity to prevent the wire icing展开更多
AIM: To evaluate the value and limitation of postoperative transcatheter arterial chemoembolization (TACE) in preventing recurrence of hepatocellular carcinoma (HCC). METHODS: In the first group, 987 postoperative pat...AIM: To evaluate the value and limitation of postoperative transcatheter arterial chemoembolization (TACE) in preventing recurrence of hepatocellular carcinoma (HCC). METHODS: In the first group, 987 postoperative patients with HCC, who did not have any evidence of recurrence in the first preventative TACE but were found to have recurrence at different times during the follow-up survey, were analyzed. In the second group, 643 postoperative patients with HCC had no TACE for compared study. To study the relationship between the recurrence time and the number of TACE treatments was analyzed. RESULTS: The 6-, 12-, and 18-mo recurrence rates in the first and second groups were 22.2% (210 cases) vs 61.6% (396 cases), 78.0% (770 cases) vs74.7% (480 cases) and 88.6% (874 cases) vs80.1% (515 cases). There were significant differences between the recurrence rates of the two groups at 6 mo (P<0.0001).CONCLUSION: The principal role of TACE after HCC operation is to suppress, detect early and treat micrometastasis. It has a good effect of preventing recurrence of HCC in 6 mo, but such an effect is less satisfactory in a longer period. When it is uncertain whether HCC is singlecentral or multi-central and if there is cancer residue or metastasis after operation, TACE is valuable to prevent recurrence.展开更多
To report a new screening method for mitochondrial DNA 1555A→G mutation and the results of genotype analysis in 19 maternal inherited deafness pedigrees. Method Five hundred and forty-six non-syndromic neuro-sensory ...To report a new screening method for mitochondrial DNA 1555A→G mutation and the results of genotype analysis in 19 maternal inherited deafness pedigrees. Method Five hundred and forty-six non-syndromic neuro-sensory hearing loss patients were tested for 1555A→G mutation using a new compact testing kit, which allows clear distinction between wild type and 1555 A→G mutated mtDNAs. Results Nineteen subjects among the 546 patients (3.48%) were found to carry mtDNA A1555G mutation. The results were confirmed by sequencing in an ABI 3100 Avant sequencer. Conclusions Maternal inherited deafness families are a frequently seen in outpatient group. The detection of mtDNA 1555 A→G mutation with a low cost, ready to use detection kit is needed and suitable in China for large scale screening and preventive testing before usage of aminoglycoside antibiotics.展开更多
Objective:To explore the therapeutic and recurrence-preventing effects of Qi-Replenishing and Blood-Activating Formula in rats with acetic acid-induced gastric ulcer.Methods:A total of 138 SD rats were selected to mak...Objective:To explore the therapeutic and recurrence-preventing effects of Qi-Replenishing and Blood-Activating Formula in rats with acetic acid-induced gastric ulcer.Methods:A total of 138 SD rats were selected to make rat models with gastric ulcer induced by acetic acid(24 rats with sham operation served as sham operation group),and were randomly divided into model group(n=30),western medicine group(n=30),traditional Chinese medicine(TCM) group(n=24) and combination group(combined western medicine and TCM group,n=30).Western medicine group was gavaged with omeprazole in the morning and with iso-volumetric distilled water in the afternoon;TCM group and TCM sham operation group were gavaged with iso-volumetric distilled water in the morning and with Qi-Replenishing and Blood-Activating Formula in the afternoon;combination group was gavaged with omeprazole in the morning and with Qi-Replenishing and Blood-Activating Formula in the afternoon;sham operation group and model group were gavaged with iso-volumetric distilled water both in the morning and afternoon.Ulcer indexes and degree of mucosal degree in rats at different time points after gavage were observed.Twentyeight days after gavage,interleukin(IL)-1β was given to induce ulcer recurrence so as to observe the recurrent severity and rate of ulcer in each group.Results:Compared with model group and western medicine group,treatment in combination group could prominently reduce the ulcer index of rats with peptic ulcer,and increase the healing rate and inhibition rate of peptic ulcer.After IL-1β-induced ulcer recurrence,combination group was significantly superior to model group and western medicine group in ulcer recurrent rate[50%(3/6) vs.100%(6/6)]and severity.Conclusions:Basic acid-suppression therapy combined with Qi-Replenishing and BloodActivating Formula can effectually improve the ulcer healing quality and reduce ulcer recurrence.展开更多
Potential’s fluctuation of rust preventing oil film during its degradation was studied using wirebeam electrode. Being non-destructive and simple, potential measurement is a very repetitive method. Otherelectrochemic...Potential’s fluctuation of rust preventing oil film during its degradation was studied using wirebeam electrode. Being non-destructive and simple, potential measurement is a very repetitive method. Otherelectrochemical testing method, e. g., polarization resistance, can breakdown the integrity of oil coating byDC current; EIS is time consuming. As a special electrochemical sensor, wire beam electrode contains 101wires of mild steel wires, and it is helpful to improve the reproducibility of electrochemical test evidently.Using this electrode, the electrochemical parameters and their distribution which was related to under filmcorrosion process are measured directly so as to describe potential’s fluctuation of rust preventing oil film. Itis pointed out that there is potential’s fluctuation on rust preventing oil film during its degradation, and thischaracteristic has direct effect on the self-repairing ability of rust preventing oil film. However, for the uncoated metal electrode and base oil film, there is no such behavior. It is also pointed out that inhibitors in theoil film have direct effect on its self-repairing ability.展开更多
Objective: To evaluate the efficacy of Jiawei Huangqi Guizhi Wuwu Decoction (加味黄芪桂枝五物汤, JHGWD) in treating neuro-sensory toxicity induced by oxaliplatin. Methods: A randomized controlled self-crossover tr...Objective: To evaluate the efficacy of Jiawei Huangqi Guizhi Wuwu Decoction (加味黄芪桂枝五物汤, JHGWD) in treating neuro-sensory toxicity induced by oxaliplatin. Methods: A randomized controlled self-crossover trial was performed. Thirty-one patients were randomly divided into AB and BA groups. Patients in A cycle belonged to the treated group, who were treated with chemotherapy combined with oxaliplatin plus JHGWD. Patients in B cycle belonged to the control group and were treated with chemotherapy alone. The peripheral neuro-sensory toxicity was observed and analyzed. Results: The main neurotoxicity was cold-induced paresthesia after the use of oxaliplatin, which included hyperaesthesia, chill, anaesthesia in the extremities, electrified sensation, formication, foreign body sensation and pain that might be exacerbated by exposure to cold. Twenty patients (64.5 % ) suffered from neuro-sensory toxicity in the treated group and 27 cases (87.1% ) in the control group. Symptoms were more serious and lasted longer in the control group than those in the treated group (P〈0.01). Conclusion: JHGWD could prevent and reduce the occurence and intensity of acute peripheral neuro-sensory toxicity caused by oxaliplatin.展开更多
Helicobacter pylori(H.pylori)infection is a major riskfactor for gastric cancer(GC)development,which isone of the most challenging malignant diseases worldwide with limited treatments.In the multistep pathogenesis of ...Helicobacter pylori(H.pylori)infection is a major riskfactor for gastric cancer(GC)development,which isone of the most challenging malignant diseases worldwide with limited treatments.In the multistep pathogenesis of GC,H.pylori infection slowly induces chronicactive gastritis,which progresses through the premalignant stages of atrophic gastritis,intestinal metaplasia,and dysplasia,and then finally to GC.Although eradication of H.pylori is a reasonable approach for the prevention of GC,there have been some contradictory reports,with only some long-term follow-up data showingefficacy of this approach.The inconsistencies are likely due to the insufficient number of participants,relatively short follow-up periods,poor quality of study designs,and the degree and extent of preneoplastic changes atthe time of H.pylori eradication.This review analyzesrecent high-quality studies to resolve the discrepancies regarding the eradication of H.pylori for GC prevention.The relationship between H.pylori eradication and GC/precancerous lesions/metachronous GC is examined,and the cost-effectiveness of this strategy in the prevention of GC is assessed.Although it is assumed that eradication of H.pylori has the potential to prevent GC,the feasibility and appropriate timing of this strategy for cancer prevention remain to be determined.As a result,additional well-designed trials with longer followup periods are needed to clarify this issue.展开更多
Based on the meteorological data in Fushun,Qingyuan and Xinbing from 1961 to 2008,the status quo of major agro-climatic resources in Fushun were analyzed.The abundant rainfall,sufficient sunshine and rich thermal reso...Based on the meteorological data in Fushun,Qingyuan and Xinbing from 1961 to 2008,the status quo of major agro-climatic resources in Fushun were analyzed.The abundant rainfall,sufficient sunshine and rich thermal resources were suitable for the development of modern agricultural production.The specific measures of effective use of climate resources were put forward according to geographical location and climatic characteristics of Fushun.The advantages of agro-climate resources were exerted for large edible fungi industry;effective accumulated temperature was applied for adjustment of plantation structure;three-dimensional agriculture in the mountainous area was developed vigorously.The main types of meteorological disasters constraining agricultural development in Fushun and their hazards were summarized,including droughts,floods,hail,etc.In addition,some scientific preventing measures of meteorological disaster were proposed.展开更多
Three different methods were applied to study the alkali content of gelpores in cement. In the closed system, the concentration of K+, Na+ and OH - have not reduced with the increase of age. In the open system, the ...Three different methods were applied to study the alkali content of gelpores in cement. In the closed system, the concentration of K+, Na+ and OH - have not reduced with the increase of age. In the open system, the diffusion and transferring of K+ and Na+ towards free space leads to the de-crease of total alkali content. In the micro-analysis system, the contents of K+ and Na+ in the first hy- drated layer of ground granulated blastfurnace slag (GBFS) are very low, while the contents of calcium and magnesium are relatively high. This phenomenon shows that the mechanism of GBFS preventing alkali aggregate reaction (AAR) is: when GBFS is dissolved by alkali medium, SiO2 and Al2O3 are dissolved into the cement matrix, then around GBFS particles form reaction rings rich in Ca2+ and Mg^2+, and the C-S-H gel of positive charges formed in the area repulses K+ and Na+, which are forced to transfer to the mortar's matrix, pore or mortar sample surface. The transferred K ^+ and Na^+ form alkali gel products with other dissolved ions, then become evenly distributed in the mortar sample and react with Ca(OH)2 in pore solutions to form (Na,K)x-2z·zCa·(SiO2)y·(OH)x gel products; and thus changes the AAR gel products' structure. The gel products will not expand, and so they can delay expansion destruction.展开更多
Since 1999, the problem of patient safety has drawn particular attention, becoming a priority in health care. A "medication error"(ME) is any preventable event occurring at any phase of the pharmacotherapy p...Since 1999, the problem of patient safety has drawn particular attention, becoming a priority in health care. A "medication error"(ME) is any preventable event occurring at any phase of the pharmacotherapy process(ordering, transcribing, dispensing, administering, and monitoring) that leads to, or can lead to, harm to the patient. Hence, MEs can involve every professional of the clinical team. MEs range from those with severe consequences to those with little or no impact on the patient. Although a high ME rate has been found in neonatal wards, newborn safety issues have not been adequately studied until now. Healthcare professionals working in neonatal wards are particularly susceptible to committing MEs due to the peculiarities of newborn patients and of the neonatal intensive care unit(NICU) environment. Current neonatal prevention strategies for MEs have been borrowed from adult wards, but many factors such as high costs and organizational barriers have hindered their diffusion. In general, two types of strategies have been proposed: the first strategy consists of identifying human factors that result in errors and redesigning the work in the NICU in order to minimize them; the second one suggests to design and implement effective systems for preventing errors or intercepting them before reaching the patient. In the future, prevention strategies for MEs need to be improved and tailored to the special neonatal population and the NICU environment and, at the same time, every effort will have to be made to support their clinical application.展开更多
Background:Football is the most practised sport in the world and is associated with the risk of injuries in the players.Some studies have been published that identify injury prevention programs,but there is no review ...Background:Football is the most practised sport in the world and is associated with the risk of injuries in the players.Some studies have been published that identify injury prevention programs,but there is no review of the full body of evidence on injury prevention programs for use by football coaches.The aim of this article was to carry out a systematic review of published studies on injury prevention programs for adult male footballers,identify points of common understanding and establish recommendations that should be considered in the design of injury prevention strategies.Methods:PubMed and EMBASE databases were used to identify relevant published articles using the following keywords:"soccer"AND"injury"AND"prevention".Results:A total of 2512 studies were identified initially,but only 11 studies met the inclusion criteria,and their outcomes are presented.Results revealed that injury prevention programs in football have focused on strength training,proprioceptive training,multicomponent programs(balance,core stability,and functional strength and mobility),and warm-up programs.Conclusion:Based on results from the studies analyzed,football players can lower the incidence of match and training injuries by participating in dynamic warm-up programs that include preventive exercises before games or during training sessions,and by adding strength,balance,and mobility training to the training sessions.展开更多
The International Maritime Organization (IMO) has encouraged its member countries to introduce Formal Safety Assessment (FSA) for ship operations since the end of the last century. FSA can be used through certain form...The International Maritime Organization (IMO) has encouraged its member countries to introduce Formal Safety Assessment (FSA) for ship operations since the end of the last century. FSA can be used through certain formal assessing steps to generate effective recommendations and cautions to control marine risks and improve the safety of ships. On the basis of the brief introduction of FSA, this paper describes the ideas of applying FSA to the prevention of human error in ship operations. It especially discusses the investigation and analysis of the information and data using navigation simulators and puts forward some suggestions for the introduction and development of the FSA research work for safer ship operations.展开更多
The aim of this study is to report on a brief alcohol intervention for preventing drinking during pregnancy. The Women’s Organizations Committee on Alcohol and Drug Issues (WOCAD) in Sweden developed an informational...The aim of this study is to report on a brief alcohol intervention for preventing drinking during pregnancy. The Women’s Organizations Committee on Alcohol and Drug Issues (WOCAD) in Sweden developed an informational brochure about alcohol during pregnancy, intended to reach pregnant women before their first visit at a prenatal clinic. A randomized controlled trial was conducted between 2004 and 2005 to measure whether the brochure had any effect. A total of 564 pregnant women between 17 and 46 years of age are included in the study. Differences between the intervention and control groups were analyzed with cross-tabulations and chi-squared tests. A multiple logistic regression analysis was also conducted to determine predictors of abstention from alcohol at the first prenatal visit. Findings show that significantly more of the women who received the brochure abstained completely from alcohol then of those who did not receive it (92% vs. 82%, p = 0.005). It was 2.6 times more likely that those who received the brochure had abstained completely from alcohol since pregnancy recognition at their first prenatal visit compared with those who did not receive it (OR = 2.6, CI 1.3 - 5.1, p = 0.005). We conclude that the informational brochure developed by WOCAD can be used in prenatal care to get more women to abstain from alcohol during pregnancy.展开更多
A V-shaped nylon net fence installed in 1990 on top of the Mogao Grottoes is shown to be effectively resisting aeolian sand damage to the grottoes. The structure guides and causes deposition of sand from westerly wind...A V-shaped nylon net fence installed in 1990 on top of the Mogao Grottoes is shown to be effectively resisting aeolian sand damage to the grottoes. The structure guides and causes deposition of sand from westerly wind (the primary hard wind), but to some extent hinders the inverse function of easterly wind carrying sand away from the grottoes toward Mount Mingsha. The gobi side by the fence experiences higher wind speed, so that on which are easily formed undercutting pits, and the deposited sands on it generally form double-peak structures due to abundant sand sources. If the earth surface characteristics in gobi areas by both sides of the fence are quite varied, the erosion and deposition features of the accumulating sand section are similar in different seasons; however, if the earth surface characteristics are similar, the features become irregular in different seasons. Sand depositions with long slope feet are formed along the south and north sides of V-shaped nylon net fence. Disrupted by strong westerly wind and northwesterly wind, sand accumulations by north of the fence are in form of single peaks. Although the operation duration of the V-shaped nylon net fence has exceeded its design life (10 years), our observations indicate that it is still effective in reducing wind-driven sand damages to the Mogao Grottoes, so it should not be withdrawn.展开更多
Acid mine drainage (AMD) that releases highly acidic, sulfate and metals-rich drainage is a serious environmental problem in coal mining areas in China. In order to study the effect of using loess for preventing AMD...Acid mine drainage (AMD) that releases highly acidic, sulfate and metals-rich drainage is a serious environmental problem in coal mining areas in China. In order to study the effect of using loess for preventing AMD and controlling heavy metals contamination from coal waste, the column leaching tests were conducted. The results come from experiment data analyses show that the loess can effectively immobilize cadmium, copper, iron, lead and zinc in AMD from coal waste, increase pH value, and decrease Eh, EC, and 8024- concentrations of AMD from coal waste. The oxidation of sulfide in coal waste is prevented by addition of the loess, which favors the generation and adsorption of the alkalinity, the decrease of the population of Thiobacillusferrooxidans, the heavy metals immobilization by precipitation of sulfide and carbonate through biological sul- fate reduction inside the column, and the halt of the oxidation process of sulfide through iron coating on the surface of sulfide in coal waste. The loess can effectively prevent AMD and heavy metals contamination from coal waste in in-situ treatment systems.展开更多
Based on years of production practice experience, the technical measures for wind prevention and sand fixation were put forward from the causes and evolu-tion laws of sand wind, which were of great realistic significa...Based on years of production practice experience, the technical measures for wind prevention and sand fixation were put forward from the causes and evolu-tion laws of sand wind, which were of great realistic significance to improve the sand prevention work in Shandong.展开更多
Coronavirus pandemic infection is the most important health issue worldwide.Coronavirus disease 2019 is a contagious disease characterized by severe acute respiratory syndrome coronavirus 2.To date,excluding the possi...Coronavirus pandemic infection is the most important health issue worldwide.Coronavirus disease 2019 is a contagious disease characterized by severe acute respiratory syndrome coronavirus 2.To date,excluding the possibility of vaccination,against SARS-CoV-2 infection it is possible to act only with supportive care and non-virus-specific treatments in order to improve the patient’s symptoms.Pharmaceutical industry is investigating effects of medicinal plants,phytochemical extracts and aromatic herbs to find out natural substances which may act as antiviral drugs.Several studies have revealed how these substances may interfere with the viral life cycle,viral entry,replication,assembly or discharge,as well as virus-specific host targets or stimulating the host immune system,reducing oxidative stress and inflammatory response.A natural compound can be used as a prophylaxis by people professionally exposed to the risk of contagion and/or positive patients not in intensive care.The aim of this paper is to perform a narrative review of current literature in order to summarize the most studied natural compounds and their modes of action.展开更多
According to the principle of effective stress action of rock and soil, we established a mechanical model of water flooding into roadways,analyzed the constitutive relation of hydrodynamic pressure and contact pressur...According to the principle of effective stress action of rock and soil, we established a mechanical model of water flooding into roadways,analyzed the constitutive relation of hydrodynamic pressure and contact pressure of rock and soil and discovered that the process of pre-grouting of a roadway curtain is a dynamically balancing process in which effective stress keeps gradually in- creasing and pore water pressure gradually declines. In such a grouting process, the initial water plugging effect is realized when the effective stress and total stress reaches equilibrium. A rigid-flexible packing layer is designed behind the brickwork to increase the effective stress and reduce pore water pressure in order to have a permanent water proof performance. This provides a theoretical basis for roadway driving and permanent water prevention. The monitoring and application results show that the initial and perma- nent waterproof theory has provided an effective method for roadway driving and making it waterproof.展开更多
文摘The evolution of coronary intervention techniques and equipment has led to more sophisticated procedures for the treatment of highly complex lesions.However,as a result,the risk of complications has increased,which are mostly iatrogenic and often include equipment failure.Stent dislodgement warrants vigilance for the early diagnosis and a stepwise management approach is required to either expand or retrieve the lost stent.In the era of bioresorbable scaffolds that are not radiopaque,increased caution is required.Intravascular imaging may assist in detecting the lost scaffold in cases of no visibility fluoroscopically.Adequate lesion preparation is the key to minimizing the possibility of equipment loss;however,in the case that it occurs,commercially available and improvised devices and techniques may be applied.
文摘Contrast-induced acute kidney injury(CI-AKI)is a major concern in clinical practice,particularly among high-risk patients with preexisting renal and cardiovascular conditions.Although periprocedural hydration has long been the primary approach for CI-AKI prevention,recent advancements have led to the development of novel approaches such as RenalGuard and contrast removal systems.This editorial explores these emerging approaches and highlights their potential for enhancing CI-AKI prevention.By incorporating the latest evidence into clinical practice,health-care professionals can more effectively maintain renal function and improve outcomes for patients undergoing contrast-enhanced procedures.
文摘This study concerns the heat transfer processes during ice accretion on wires. The steady state heat balance equation assumed to describe the thermodynamics at the surface of a current heated wire subjected to icing is obtained by analyzing and computing each terms of heat flux. The surface temperature of wire is derived from the heat balance equation, which gives out a proposed estimation of the current intensity to prevent the wire icing
文摘AIM: To evaluate the value and limitation of postoperative transcatheter arterial chemoembolization (TACE) in preventing recurrence of hepatocellular carcinoma (HCC). METHODS: In the first group, 987 postoperative patients with HCC, who did not have any evidence of recurrence in the first preventative TACE but were found to have recurrence at different times during the follow-up survey, were analyzed. In the second group, 643 postoperative patients with HCC had no TACE for compared study. To study the relationship between the recurrence time and the number of TACE treatments was analyzed. RESULTS: The 6-, 12-, and 18-mo recurrence rates in the first and second groups were 22.2% (210 cases) vs 61.6% (396 cases), 78.0% (770 cases) vs74.7% (480 cases) and 88.6% (874 cases) vs80.1% (515 cases). There were significant differences between the recurrence rates of the two groups at 6 mo (P<0.0001).CONCLUSION: The principal role of TACE after HCC operation is to suppress, detect early and treat micrometastasis. It has a good effect of preventing recurrence of HCC in 6 mo, but such an effect is less satisfactory in a longer period. When it is uncertain whether HCC is singlecentral or multi-central and if there is cancer residue or metastasis after operation, TACE is valuable to prevent recurrence.
文摘To report a new screening method for mitochondrial DNA 1555A→G mutation and the results of genotype analysis in 19 maternal inherited deafness pedigrees. Method Five hundred and forty-six non-syndromic neuro-sensory hearing loss patients were tested for 1555A→G mutation using a new compact testing kit, which allows clear distinction between wild type and 1555 A→G mutated mtDNAs. Results Nineteen subjects among the 546 patients (3.48%) were found to carry mtDNA A1555G mutation. The results were confirmed by sequencing in an ABI 3100 Avant sequencer. Conclusions Maternal inherited deafness families are a frequently seen in outpatient group. The detection of mtDNA 1555 A→G mutation with a low cost, ready to use detection kit is needed and suitable in China for large scale screening and preventive testing before usage of aminoglycoside antibiotics.
基金financially supported by Suzhou Science and Technology Bureau Project(SYS201366)Jiangsu Provincial Science and Technology Project of Traditional Chinese Medicing Bureau(YB2015097)
文摘Objective:To explore the therapeutic and recurrence-preventing effects of Qi-Replenishing and Blood-Activating Formula in rats with acetic acid-induced gastric ulcer.Methods:A total of 138 SD rats were selected to make rat models with gastric ulcer induced by acetic acid(24 rats with sham operation served as sham operation group),and were randomly divided into model group(n=30),western medicine group(n=30),traditional Chinese medicine(TCM) group(n=24) and combination group(combined western medicine and TCM group,n=30).Western medicine group was gavaged with omeprazole in the morning and with iso-volumetric distilled water in the afternoon;TCM group and TCM sham operation group were gavaged with iso-volumetric distilled water in the morning and with Qi-Replenishing and Blood-Activating Formula in the afternoon;combination group was gavaged with omeprazole in the morning and with Qi-Replenishing and Blood-Activating Formula in the afternoon;sham operation group and model group were gavaged with iso-volumetric distilled water both in the morning and afternoon.Ulcer indexes and degree of mucosal degree in rats at different time points after gavage were observed.Twentyeight days after gavage,interleukin(IL)-1β was given to induce ulcer recurrence so as to observe the recurrent severity and rate of ulcer in each group.Results:Compared with model group and western medicine group,treatment in combination group could prominently reduce the ulcer index of rats with peptic ulcer,and increase the healing rate and inhibition rate of peptic ulcer.After IL-1β-induced ulcer recurrence,combination group was significantly superior to model group and western medicine group in ulcer recurrent rate[50%(3/6) vs.100%(6/6)]and severity.Conclusions:Basic acid-suppression therapy combined with Qi-Replenishing and BloodActivating Formula can effectually improve the ulcer healing quality and reduce ulcer recurrence.
文摘Potential’s fluctuation of rust preventing oil film during its degradation was studied using wirebeam electrode. Being non-destructive and simple, potential measurement is a very repetitive method. Otherelectrochemical testing method, e. g., polarization resistance, can breakdown the integrity of oil coating byDC current; EIS is time consuming. As a special electrochemical sensor, wire beam electrode contains 101wires of mild steel wires, and it is helpful to improve the reproducibility of electrochemical test evidently.Using this electrode, the electrochemical parameters and their distribution which was related to under filmcorrosion process are measured directly so as to describe potential’s fluctuation of rust preventing oil film. Itis pointed out that there is potential’s fluctuation on rust preventing oil film during its degradation, and thischaracteristic has direct effect on the self-repairing ability of rust preventing oil film. However, for the uncoated metal electrode and base oil film, there is no such behavior. It is also pointed out that inhibitors in theoil film have direct effect on its self-repairing ability.
文摘Objective: To evaluate the efficacy of Jiawei Huangqi Guizhi Wuwu Decoction (加味黄芪桂枝五物汤, JHGWD) in treating neuro-sensory toxicity induced by oxaliplatin. Methods: A randomized controlled self-crossover trial was performed. Thirty-one patients were randomly divided into AB and BA groups. Patients in A cycle belonged to the treated group, who were treated with chemotherapy combined with oxaliplatin plus JHGWD. Patients in B cycle belonged to the control group and were treated with chemotherapy alone. The peripheral neuro-sensory toxicity was observed and analyzed. Results: The main neurotoxicity was cold-induced paresthesia after the use of oxaliplatin, which included hyperaesthesia, chill, anaesthesia in the extremities, electrified sensation, formication, foreign body sensation and pain that might be exacerbated by exposure to cold. Twenty patients (64.5 % ) suffered from neuro-sensory toxicity in the treated group and 27 cases (87.1% ) in the control group. Symptoms were more serious and lasted longer in the control group than those in the treated group (P〈0.01). Conclusion: JHGWD could prevent and reduce the occurence and intensity of acute peripheral neuro-sensory toxicity caused by oxaliplatin.
文摘Helicobacter pylori(H.pylori)infection is a major riskfactor for gastric cancer(GC)development,which isone of the most challenging malignant diseases worldwide with limited treatments.In the multistep pathogenesis of GC,H.pylori infection slowly induces chronicactive gastritis,which progresses through the premalignant stages of atrophic gastritis,intestinal metaplasia,and dysplasia,and then finally to GC.Although eradication of H.pylori is a reasonable approach for the prevention of GC,there have been some contradictory reports,with only some long-term follow-up data showingefficacy of this approach.The inconsistencies are likely due to the insufficient number of participants,relatively short follow-up periods,poor quality of study designs,and the degree and extent of preneoplastic changes atthe time of H.pylori eradication.This review analyzesrecent high-quality studies to resolve the discrepancies regarding the eradication of H.pylori for GC prevention.The relationship between H.pylori eradication and GC/precancerous lesions/metachronous GC is examined,and the cost-effectiveness of this strategy in the prevention of GC is assessed.Although it is assumed that eradication of H.pylori has the potential to prevent GC,the feasibility and appropriate timing of this strategy for cancer prevention remain to be determined.As a result,additional well-designed trials with longer followup periods are needed to clarify this issue.
基金Supported by Fushun Government Substance Subject (20071209)
文摘Based on the meteorological data in Fushun,Qingyuan and Xinbing from 1961 to 2008,the status quo of major agro-climatic resources in Fushun were analyzed.The abundant rainfall,sufficient sunshine and rich thermal resources were suitable for the development of modern agricultural production.The specific measures of effective use of climate resources were put forward according to geographical location and climatic characteristics of Fushun.The advantages of agro-climate resources were exerted for large edible fungi industry;effective accumulated temperature was applied for adjustment of plantation structure;three-dimensional agriculture in the mountainous area was developed vigorously.The main types of meteorological disasters constraining agricultural development in Fushun and their hazards were summarized,including droughts,floods,hail,etc.In addition,some scientific preventing measures of meteorological disaster were proposed.
基金Funded by the German Academic Exchange Service (DAAD) for the Project A/09/00743the Science and Technology Project of Wuhan City(No.200860423208)
文摘Three different methods were applied to study the alkali content of gelpores in cement. In the closed system, the concentration of K+, Na+ and OH - have not reduced with the increase of age. In the open system, the diffusion and transferring of K+ and Na+ towards free space leads to the de-crease of total alkali content. In the micro-analysis system, the contents of K+ and Na+ in the first hy- drated layer of ground granulated blastfurnace slag (GBFS) are very low, while the contents of calcium and magnesium are relatively high. This phenomenon shows that the mechanism of GBFS preventing alkali aggregate reaction (AAR) is: when GBFS is dissolved by alkali medium, SiO2 and Al2O3 are dissolved into the cement matrix, then around GBFS particles form reaction rings rich in Ca2+ and Mg^2+, and the C-S-H gel of positive charges formed in the area repulses K+ and Na+, which are forced to transfer to the mortar's matrix, pore or mortar sample surface. The transferred K ^+ and Na^+ form alkali gel products with other dissolved ions, then become evenly distributed in the mortar sample and react with Ca(OH)2 in pore solutions to form (Na,K)x-2z·zCa·(SiO2)y·(OH)x gel products; and thus changes the AAR gel products' structure. The gel products will not expand, and so they can delay expansion destruction.
文摘Since 1999, the problem of patient safety has drawn particular attention, becoming a priority in health care. A "medication error"(ME) is any preventable event occurring at any phase of the pharmacotherapy process(ordering, transcribing, dispensing, administering, and monitoring) that leads to, or can lead to, harm to the patient. Hence, MEs can involve every professional of the clinical team. MEs range from those with severe consequences to those with little or no impact on the patient. Although a high ME rate has been found in neonatal wards, newborn safety issues have not been adequately studied until now. Healthcare professionals working in neonatal wards are particularly susceptible to committing MEs due to the peculiarities of newborn patients and of the neonatal intensive care unit(NICU) environment. Current neonatal prevention strategies for MEs have been borrowed from adult wards, but many factors such as high costs and organizational barriers have hindered their diffusion. In general, two types of strategies have been proposed: the first strategy consists of identifying human factors that result in errors and redesigning the work in the NICU in order to minimize them; the second one suggests to design and implement effective systems for preventing errors or intercepting them before reaching the patient. In the future, prevention strategies for MEs need to be improved and tailored to the special neonatal population and the NICU environment and, at the same time, every effort will have to be made to support their clinical application.
文摘Background:Football is the most practised sport in the world and is associated with the risk of injuries in the players.Some studies have been published that identify injury prevention programs,but there is no review of the full body of evidence on injury prevention programs for use by football coaches.The aim of this article was to carry out a systematic review of published studies on injury prevention programs for adult male footballers,identify points of common understanding and establish recommendations that should be considered in the design of injury prevention strategies.Methods:PubMed and EMBASE databases were used to identify relevant published articles using the following keywords:"soccer"AND"injury"AND"prevention".Results:A total of 2512 studies were identified initially,but only 11 studies met the inclusion criteria,and their outcomes are presented.Results revealed that injury prevention programs in football have focused on strength training,proprioceptive training,multicomponent programs(balance,core stability,and functional strength and mobility),and warm-up programs.Conclusion:Based on results from the studies analyzed,football players can lower the incidence of match and training injuries by participating in dynamic warm-up programs that include preventive exercises before games or during training sessions,and by adding strength,balance,and mobility training to the training sessions.
文摘The International Maritime Organization (IMO) has encouraged its member countries to introduce Formal Safety Assessment (FSA) for ship operations since the end of the last century. FSA can be used through certain formal assessing steps to generate effective recommendations and cautions to control marine risks and improve the safety of ships. On the basis of the brief introduction of FSA, this paper describes the ideas of applying FSA to the prevention of human error in ship operations. It especially discusses the investigation and analysis of the information and data using navigation simulators and puts forward some suggestions for the introduction and development of the FSA research work for safer ship operations.
文摘The aim of this study is to report on a brief alcohol intervention for preventing drinking during pregnancy. The Women’s Organizations Committee on Alcohol and Drug Issues (WOCAD) in Sweden developed an informational brochure about alcohol during pregnancy, intended to reach pregnant women before their first visit at a prenatal clinic. A randomized controlled trial was conducted between 2004 and 2005 to measure whether the brochure had any effect. A total of 564 pregnant women between 17 and 46 years of age are included in the study. Differences between the intervention and control groups were analyzed with cross-tabulations and chi-squared tests. A multiple logistic regression analysis was also conducted to determine predictors of abstention from alcohol at the first prenatal visit. Findings show that significantly more of the women who received the brochure abstained completely from alcohol then of those who did not receive it (92% vs. 82%, p = 0.005). It was 2.6 times more likely that those who received the brochure had abstained completely from alcohol since pregnancy recognition at their first prenatal visit compared with those who did not receive it (OR = 2.6, CI 1.3 - 5.1, p = 0.005). We conclude that the informational brochure developed by WOCAD can be used in prenatal care to get more women to abstain from alcohol during pregnancy.
基金supported jointly by the National Science and Technology Support Program (2012BAC08B07)the Natural Science Foundation of China (Nos. 2009BAC54B01-1 and 40930741)the Knowledge Innovation Program of the Chinese Academy of Sciences (KZCX2-EW-313)
文摘A V-shaped nylon net fence installed in 1990 on top of the Mogao Grottoes is shown to be effectively resisting aeolian sand damage to the grottoes. The structure guides and causes deposition of sand from westerly wind (the primary hard wind), but to some extent hinders the inverse function of easterly wind carrying sand away from the grottoes toward Mount Mingsha. The gobi side by the fence experiences higher wind speed, so that on which are easily formed undercutting pits, and the deposited sands on it generally form double-peak structures due to abundant sand sources. If the earth surface characteristics in gobi areas by both sides of the fence are quite varied, the erosion and deposition features of the accumulating sand section are similar in different seasons; however, if the earth surface characteristics are similar, the features become irregular in different seasons. Sand depositions with long slope feet are formed along the south and north sides of V-shaped nylon net fence. Disrupted by strong westerly wind and northwesterly wind, sand accumulations by north of the fence are in form of single peaks. Although the operation duration of the V-shaped nylon net fence has exceeded its design life (10 years), our observations indicate that it is still effective in reducing wind-driven sand damages to the Mogao Grottoes, so it should not be withdrawn.
基金Supported by the-National Natural Science Foundation of China (30671448) the Science and Technology Pillar Program of Hebei Province 12220802D)
文摘Acid mine drainage (AMD) that releases highly acidic, sulfate and metals-rich drainage is a serious environmental problem in coal mining areas in China. In order to study the effect of using loess for preventing AMD and controlling heavy metals contamination from coal waste, the column leaching tests were conducted. The results come from experiment data analyses show that the loess can effectively immobilize cadmium, copper, iron, lead and zinc in AMD from coal waste, increase pH value, and decrease Eh, EC, and 8024- concentrations of AMD from coal waste. The oxidation of sulfide in coal waste is prevented by addition of the loess, which favors the generation and adsorption of the alkalinity, the decrease of the population of Thiobacillusferrooxidans, the heavy metals immobilization by precipitation of sulfide and carbonate through biological sul- fate reduction inside the column, and the halt of the oxidation process of sulfide through iron coating on the surface of sulfide in coal waste. The loess can effectively prevent AMD and heavy metals contamination from coal waste in in-situ treatment systems.
文摘Based on years of production practice experience, the technical measures for wind prevention and sand fixation were put forward from the causes and evolu-tion laws of sand wind, which were of great realistic significance to improve the sand prevention work in Shandong.
文摘Coronavirus pandemic infection is the most important health issue worldwide.Coronavirus disease 2019 is a contagious disease characterized by severe acute respiratory syndrome coronavirus 2.To date,excluding the possibility of vaccination,against SARS-CoV-2 infection it is possible to act only with supportive care and non-virus-specific treatments in order to improve the patient’s symptoms.Pharmaceutical industry is investigating effects of medicinal plants,phytochemical extracts and aromatic herbs to find out natural substances which may act as antiviral drugs.Several studies have revealed how these substances may interfere with the viral life cycle,viral entry,replication,assembly or discharge,as well as virus-specific host targets or stimulating the host immune system,reducing oxidative stress and inflammatory response.A natural compound can be used as a prophylaxis by people professionally exposed to the risk of contagion and/or positive patients not in intensive care.The aim of this paper is to perform a narrative review of current literature in order to summarize the most studied natural compounds and their modes of action.
基金Projects 50774078 supported by the National Natural Science Foundation of China 2007CB209400 by the National Basic Research Program of China
文摘According to the principle of effective stress action of rock and soil, we established a mechanical model of water flooding into roadways,analyzed the constitutive relation of hydrodynamic pressure and contact pressure of rock and soil and discovered that the process of pre-grouting of a roadway curtain is a dynamically balancing process in which effective stress keeps gradually in- creasing and pore water pressure gradually declines. In such a grouting process, the initial water plugging effect is realized when the effective stress and total stress reaches equilibrium. A rigid-flexible packing layer is designed behind the brickwork to increase the effective stress and reduce pore water pressure in order to have a permanent water proof performance. This provides a theoretical basis for roadway driving and permanent water prevention. The monitoring and application results show that the initial and perma- nent waterproof theory has provided an effective method for roadway driving and making it waterproof.