Complex tibial plateau fractures can seriously affect quality of life and physical and mental health of patients.The anatomical relationship between the proximal tibial bone and soft tissue is complex,resulting in dif...Complex tibial plateau fractures can seriously affect quality of life and physical and mental health of patients.The anatomical relationship between the proximal tibial bone and soft tissue is complex,resulting in different types of tibial plateau fractures.Violent trauma can lead to displaced fracture,serious soft tissue injury,and potentially,dislocation of the knee joint.Therefore,tibial plateau fractures are extremely unstable.AIM To assess the use of locking compression plate(LCP)+T-type steel plate for postoperative weight bearing and functional recovery of complex tibial plateau fractures.METHODS Ninety-seven patients with complex tibial plateau fractures who underwent surgery at our hospital were selected for retrospective study.Forty-nine patients had been treated with LCP+T-type steel plate limited internal fixation(study group),and 48 patients with bilateral ordinary steel plate support(control group).The operation process index,postoperative rehabilitation related index,Rasmussen score of the knee joint,tibial plateau varus angle(TPA),tibial plateau retroversion angle(PA),and surgical complications of the two groups were compared.RESULTS The operation time and intraoperative bone graft volume in the study group were lower than those in the control group(P<0.05).There were no significant differences in surgical bleeding,anterior external incision length,postoperative drainage,hospital stay duration,and fracture healing time between the groups(P>0.05).There was no significant difference in the TPA and PA angle between the groups immediately and 18 mo after surgery(P>0.05).At 12 mo after surgery,the Rasmussen scale score was higher in the study group than in the control group(P<0.05).There was no significant difference in the Rasmussen scale score at 18 mo after surgery,and the radiology score at 12 and 18 mo after surgery,between the two groups(P>0.05).The postoperative complication rate in the study group(3.77%)was lower than that in the control group(15.09%;P<0.05).CONCLUSION LCP+T-type steel plate internal fixation has advantages in terms of minimizing trauma and enabling early postoperative functional exercise,promoting functional recovery and lower limb weight-bearing,and reducing postoperative complications.展开更多
Objective:To compare the clinical therapeutic effect of bridge combined internal fixation system and locking compression plate internal fixation in the treatment of displaced midshaft clavicle fractures by emphaticall...Objective:To compare the clinical therapeutic effect of bridge combined internal fixation system and locking compression plate internal fixation in the treatment of displaced midshaft clavicle fractures by emphatically observing fracture healing and shoulder joint function.Methods:Totally 44 elderly patients with Robinson type 2B displaced midshaft clavicle fractures were included from the Department of Orthopaedics,Shenyang Fourth People's Hospital during February 2016 and December 2018,including 23 males and 21 females,mean age(69.8±10.2)years old.The patients were divided into a bridge combined internal fixation system group(bridge group,n=22)and a locking compression plate internal fixation group(plate group,n=22)according to the internal fixation methods.The operation time,intraoperative blood loss,fracture healing time,and postoperative complications were recorded.At 12 months after surgery,the shoulder joint Constant-Murley score and DASH score were used to assess the recovery of joint function.The serum levels of bone turnover biochemical markers procollagen I N-terminal peptide(P1NP),cross-linked Carboxy-terminal telopeptide of typeⅠcollagen(CTX-I),and osteoblast specific factor(OSF)were measured before and 3 months after surgery.Results:The operation time,intraoperative blood loss and fracture healing time of the bridge group were significantly shorter than those of the plate group(P<0.05).Constant scores and DASH scores in the bridge group were significantly better than those of the plate group at 12 months after surgery(P<0.05).Serum levels of CTX-I was significantly decreased,while the P1NP and OSF were significantly increased compared with before surgery in the both groups(P<0.05),and the changes were more obvious in the bridge group(P<0.05).The incidence of complications was similar between the two groups(P<0.05).Conclusion:Compared with the locking plate system,the bridge combined internal fixation system can effectively improve the operation efficiency,have more benefits on fracture healing,better promote the recovery of patients'function,and reduce the failure rate of internal fixation,thus providing a better choice to treat displaced midshaft clavicle fractures by intraoperative internal fixation.展开更多
The interaction functions of electrically coupled Hindmarsh–Rose（HR） neurons for different firing patterns are investigated in this paper.By applying the phase reduction technique,the phase response curve（PRC） of...The interaction functions of electrically coupled Hindmarsh–Rose（HR） neurons for different firing patterns are investigated in this paper.By applying the phase reduction technique,the phase response curve（PRC） of the spiking neuron and burst phase response curve（BPRC） of the bursting neuron are derived.Then the interaction function of two coupled neurons can be calculated numerically according to the PRC（or BPRC） and the voltage time course of the neurons.Results show that the BPRC is more and more complicated with the increase of the spike number within a burst,and the curve of the interaction function oscillates more and more frequently with it.However,two certain things are unchanged：Φ = 0,which corresponds to the in-phase synchronization state,is always the stable equilibrium,while the anti-phase synchronization state with Φ = 0.5 is an unstable equilibrium.展开更多
A low jitter All-Digital Phase-Locked Loop （ADPLL） used as a clock generator is designed. The Digital-Controlled Oscillator （DCO） for this ADPLL is a seven-stage ring oscillator with the delay of each stage change...A low jitter All-Digital Phase-Locked Loop （ADPLL） used as a clock generator is designed. The Digital-Controlled Oscillator （DCO） for this ADPLL is a seven-stage ring oscillator with the delay of each stage changeable. Based on the Impulse Sensitivity Function （ISF） analysis, an effective way is proposed to reduce the ADPLL＇s jitter by the careful design of the sizes of the inverters used in the DCO with a simple architecture other than a complex one. The ADPLL is implemented in a 0.18μm CMOS process with 1.SV supply voltage, occupies 0.046mm^2 of on-chip area. According to the measured results, the ADPLL can operate from 108MHz to 304MHz, and the peak-to-peak jitter is 139ps when the DCO＇s output frequency is 188MHz.展开更多
睡眠分期是评估睡眠质量的基础。然而,睡眠呼吸暂停(sleep apnea,SA)会改变测试者的睡眠结构,进而影响对睡眠分期的准确评估。因此,在评估睡眠质量时,准确检测睡眠呼吸暂停和睡眠分期至关重要。为准确评估睡眠分期,本研究通过研究脑区...睡眠分期是评估睡眠质量的基础。然而,睡眠呼吸暂停(sleep apnea,SA)会改变测试者的睡眠结构,进而影响对睡眠分期的准确评估。因此,在评估睡眠质量时,准确检测睡眠呼吸暂停和睡眠分期至关重要。为准确评估睡眠分期,本研究通过研究脑区之间的功能连接,探讨了脑功能连接的相互作用关系。采用锁相值(phase locking value,PLV)在不同时间段上进行特征提取,构建功能连接网络;然后利用多个时间段的PLV进行特征融合,并通过LibSVM(library for support vector machines,LibSVM)结合分类性能优化策略的方法进行睡眠分期。同时,本研究还分析了睡眠呼吸暂停和正常呼吸对脑网络的影响。实验结果显示,睡眠呼吸暂停时的各脑区连通紧密程度大于正常呼吸时,并在子时段数为30时,睡眠分期的分类准确率达到了88.87%,呼吸暂停的检测准确率达到了93.64%。该算法在睡眠分类和呼吸暂停检测方面表现出良好性能,有助于推动脑电睡眠分类和呼吸暂停检测系统的开发和应用。展开更多
文摘Complex tibial plateau fractures can seriously affect quality of life and physical and mental health of patients.The anatomical relationship between the proximal tibial bone and soft tissue is complex,resulting in different types of tibial plateau fractures.Violent trauma can lead to displaced fracture,serious soft tissue injury,and potentially,dislocation of the knee joint.Therefore,tibial plateau fractures are extremely unstable.AIM To assess the use of locking compression plate(LCP)+T-type steel plate for postoperative weight bearing and functional recovery of complex tibial plateau fractures.METHODS Ninety-seven patients with complex tibial plateau fractures who underwent surgery at our hospital were selected for retrospective study.Forty-nine patients had been treated with LCP+T-type steel plate limited internal fixation(study group),and 48 patients with bilateral ordinary steel plate support(control group).The operation process index,postoperative rehabilitation related index,Rasmussen score of the knee joint,tibial plateau varus angle(TPA),tibial plateau retroversion angle(PA),and surgical complications of the two groups were compared.RESULTS The operation time and intraoperative bone graft volume in the study group were lower than those in the control group(P<0.05).There were no significant differences in surgical bleeding,anterior external incision length,postoperative drainage,hospital stay duration,and fracture healing time between the groups(P>0.05).There was no significant difference in the TPA and PA angle between the groups immediately and 18 mo after surgery(P>0.05).At 12 mo after surgery,the Rasmussen scale score was higher in the study group than in the control group(P<0.05).There was no significant difference in the Rasmussen scale score at 18 mo after surgery,and the radiology score at 12 and 18 mo after surgery,between the two groups(P>0.05).The postoperative complication rate in the study group(3.77%)was lower than that in the control group(15.09%;P<0.05).CONCLUSION LCP+T-type steel plate internal fixation has advantages in terms of minimizing trauma and enabling early postoperative functional exercise,promoting functional recovery and lower limb weight-bearing,and reducing postoperative complications.
文摘Objective:To compare the clinical therapeutic effect of bridge combined internal fixation system and locking compression plate internal fixation in the treatment of displaced midshaft clavicle fractures by emphatically observing fracture healing and shoulder joint function.Methods:Totally 44 elderly patients with Robinson type 2B displaced midshaft clavicle fractures were included from the Department of Orthopaedics,Shenyang Fourth People's Hospital during February 2016 and December 2018,including 23 males and 21 females,mean age(69.8±10.2)years old.The patients were divided into a bridge combined internal fixation system group(bridge group,n=22)and a locking compression plate internal fixation group(plate group,n=22)according to the internal fixation methods.The operation time,intraoperative blood loss,fracture healing time,and postoperative complications were recorded.At 12 months after surgery,the shoulder joint Constant-Murley score and DASH score were used to assess the recovery of joint function.The serum levels of bone turnover biochemical markers procollagen I N-terminal peptide(P1NP),cross-linked Carboxy-terminal telopeptide of typeⅠcollagen(CTX-I),and osteoblast specific factor(OSF)were measured before and 3 months after surgery.Results:The operation time,intraoperative blood loss and fracture healing time of the bridge group were significantly shorter than those of the plate group(P<0.05).Constant scores and DASH scores in the bridge group were significantly better than those of the plate group at 12 months after surgery(P<0.05).Serum levels of CTX-I was significantly decreased,while the P1NP and OSF were significantly increased compared with before surgery in the both groups(P<0.05),and the changes were more obvious in the bridge group(P<0.05).The incidence of complications was similar between the two groups(P<0.05).Conclusion:Compared with the locking plate system,the bridge combined internal fixation system can effectively improve the operation efficiency,have more benefits on fracture healing,better promote the recovery of patients'function,and reduce the failure rate of internal fixation,thus providing a better choice to treat displaced midshaft clavicle fractures by intraoperative internal fixation.
基金Project supported by the National Natural Science Foundation of China(Grant Nos.11272065 and 11472061)
文摘The interaction functions of electrically coupled Hindmarsh–Rose（HR） neurons for different firing patterns are investigated in this paper.By applying the phase reduction technique,the phase response curve（PRC） of the spiking neuron and burst phase response curve（BPRC） of the bursting neuron are derived.Then the interaction function of two coupled neurons can be calculated numerically according to the PRC（or BPRC） and the voltage time course of the neurons.Results show that the BPRC is more and more complicated with the increase of the spike number within a burst,and the curve of the interaction function oscillates more and more frequently with it.However,two certain things are unchanged：Φ = 0,which corresponds to the in-phase synchronization state,is always the stable equilibrium,while the anti-phase synchronization state with Φ = 0.5 is an unstable equilibrium.
文摘A low jitter All-Digital Phase-Locked Loop （ADPLL） used as a clock generator is designed. The Digital-Controlled Oscillator （DCO） for this ADPLL is a seven-stage ring oscillator with the delay of each stage changeable. Based on the Impulse Sensitivity Function （ISF） analysis, an effective way is proposed to reduce the ADPLL＇s jitter by the careful design of the sizes of the inverters used in the DCO with a simple architecture other than a complex one. The ADPLL is implemented in a 0.18μm CMOS process with 1.SV supply voltage, occupies 0.046mm^2 of on-chip area. According to the measured results, the ADPLL can operate from 108MHz to 304MHz, and the peak-to-peak jitter is 139ps when the DCO＇s output frequency is 188MHz.
文摘睡眠分期是评估睡眠质量的基础。然而,睡眠呼吸暂停(sleep apnea,SA)会改变测试者的睡眠结构,进而影响对睡眠分期的准确评估。因此,在评估睡眠质量时,准确检测睡眠呼吸暂停和睡眠分期至关重要。为准确评估睡眠分期,本研究通过研究脑区之间的功能连接,探讨了脑功能连接的相互作用关系。采用锁相值(phase locking value,PLV)在不同时间段上进行特征提取,构建功能连接网络;然后利用多个时间段的PLV进行特征融合,并通过LibSVM(library for support vector machines,LibSVM)结合分类性能优化策略的方法进行睡眠分期。同时,本研究还分析了睡眠呼吸暂停和正常呼吸对脑网络的影响。实验结果显示,睡眠呼吸暂停时的各脑区连通紧密程度大于正常呼吸时,并在子时段数为30时,睡眠分期的分类准确率达到了88.87%,呼吸暂停的检测准确率达到了93.64%。该算法在睡眠分类和呼吸暂停检测方面表现出良好性能,有助于推动脑电睡眠分类和呼吸暂停检测系统的开发和应用。
