Visual analysis of flow and diffusion of hemolytic agents and hematomas

The elimination of intracranial hematomas has received widespread attention and the interactions between hemolytic agents and hematomas have become a hot research topic.In this study,we used the Navier-Stokes equation to describe the flow control equation for hemolytic agents in a tube and used Fick’s law and the Maxwell-Stefan diffusion theory to describe the diffusion and mass transfer of hemolytic agents and hematomas.The physical fields and initial boundary conditions were set according to the parametric properties of the fluid and drainage tube.The COMSOL Multiphysics software was used to simulate the streamline distribution of hemolytic agents in a bifurcated drainage tube.Additionally,the diffusion behaviors of the hemolytic agents into hematomas were simulated and visual analysis of coupled multiphysics was performed to realize the digitization and visualization of engineering fluid problems and contribute to the field of medical engineering.

Mathematical Modeling of Biological Fluid Flow Through a Cylindrical Layer with Due Account for Barodiffusion

The work proposes a model of biological fluid flow in a steady mode through a cylindrical layer taking into account convection and diffusion.The model considers finite compressibility and concentration expansion connected with both barodiffusion and additional mechanism of pressure change in the pore volume due to the concentration gradient.Thus,the model is entirely coupled.The paper highlights the complexes composed of scales of physical quantities of different natures.The iteration algorithm for the numerical solution of the problem was developed for the coupled problem.The work involves numerical studies of the considered effects on the characteristics of the flow that can be convective or diffusive,depending on the relation between the dimensionless complexes.It is demonstrated that the distribution of velocity and concentration for different cylinder wall thicknesses is different.It is established that the barodiffusion has a considerable impact on the process in the convective mode or in the case of reduced cylinder wall thickness.

SELECTIVE SULFUR DIOXIDE DETERMINATION BY GAS DIFFUSION FLOW INJECTION ANALYSIS WITH CHEMILUMINESCENT DETECTION

Sulfur dioxide has been found to decrease the chemiluminescence of luminol-iodine system.A new determination method for sulfur dioxide in atmosphere is developed by applying this reaction to a flow injection gas diffusion separation system.This permits the determination of sulfur dioxide selectively and rapidly.

Numerical Simulation of Diffusion Type Traffic Flow Model Using Second-Order Lax-Wendroff Scheme Based on Exponential Velocity Density Function

In order to control traffic congestion, many mathematical models have been used for several decades. In this paper, we study diffusion-type traffic flow model based on exponential velocity density relation, which provides a non-linear second-order parabolic partial differential equation. The analytical solution of the diffusion-type traffic flow model is very complicated to approximate the initial density of the Cauchy problem as a function of x from given data and it may cause a huge error. For the complexity of the analytical solution, the numerical solution is performed by implementing an explicit upwind, explicitly centered, and second-order Lax-Wendroff scheme for the numerical solution. From the comparison of relative error among these three schemes, it is observed that Lax-Wendroff scheme gives less error than the explicit upwind and explicit centered difference scheme. The numerical, analytical analysis and comparative result discussion bring out the fact that the Lax-Wendroff scheme with exponential velocity-density relation of diffusion type traffic flow model is suitable for the congested area and shows a better fit in traffic-congested regions.

Solutions Of Boundary-Value Problems of the Generalized Theory of Couple-Stress Thermodiffusion

We have considered the basic dynamic homogeneous system of partial differential equations of generalized Green-Lindsay couple-stress thermodiffusion on the plane for homogeneous, isotropic elastic media with the centre of symmetry. We have constructed regular solution of the boundary problems on the line. In the works are obtained in quadrates the solution of the boundary-value problem of the generalized Green-Lindsay theory of couple-stress thermodiffusion, when on border of area are given： the component of normal of displacement vector, the component of touching of stress vector, rotations, flow of heat and flow of diffusion.

Theoretical Calculations and Experimental Verification for the Pumping Effect Caused by the Dynamic Micro-tapered Angle

The atomizer with micro cone apertures has advantages of ultra-fine atomized droplets, low power consumption and low temperature rise. The current research of this kind of atomizer mainly focuses on the performance and its application while there is less research of the principle of the atomization. Under the analysis of the dispenser and its micro-tapered aperture＇s deformation, the volume changes during the deformation and vibration of the micro-tapered aperture on the dispenser are calculated by coordinate transformation. Based on the characters of the flow resistance in a cone aperture, it is found that the dynamic cone angle results from periodical changes of the volume of the micro-tapered aperture of the atomizer and this change drives one-way flows. Besides, an experimental atomization platform is established to measure the atomization rates with different resonance frequencies of the cone aperture atomizer. The atomization performances of cone aperture and straight aperture atomizers are also measured. The experimental results show the existence of the pumping effect of the dynamic tapered angle. This effect is usually observed in industries that require low dispersion and micro- and nanoscale grain sizes, such as during production of high-pressure nozzles and inhalation therapy. Strategies to minimize the pumping effect of the dynamic cone angle or improve future designs are important concerns. This research proposes that dynamic micro-tapered angle is an important cause of atomization of the atomizer with micro cone apertures.

Rate decline analysis of multiple fractured horizontal well in shale reservoir with triple continuum

Multiple fractured horizontal well(MFHW) is widely applied in the development of shale gas. To investigate the gas flow characteristics in shale, based on a new dual mechanism triple continuum model, an analytical solution for MFHW surrounded by stimulated reservoir volume(SRV) was presented. Pressure and pressure derivative curves were used to identify the characteristics of flow regimes in shale. Blasingame type curves were established to evaluate the effects of sensitive parameters on rate decline curves, which indicates that the whole flow regimes could be divided into transient flow, feeding flow, and pseudo steady state flow. In feeding flow regime, the production of gas well is gradually fed by adsorbed gases in sub matrix, and free gases in matrix. The proportion of different gas sources to well production is determined by such parameters as storability ratios of triple continuum, transmissibility coefficients controlled by dual flow mechanism and fracture conductivity.

A brief report on MRI investigation of experimental traumatic brain injury

Traumatic brain injury is a major cause of death and disability. This is a brief report based on a symposium presentation to the 2014 Chinese Neurotrauma Association Meeting in San Francisco, USA. It covers the work from our laboratory in applying multimodal MRI to study experimental traumatic brain injury in rats with comparisons made to behavioral tests and histology. MRI protocols include structural, perfusion, manganese-enhanced, diffusion-tensor MRI, and MRI of blood-brain barrier integrity and cerebrovascular reactivity.

LIFE SPAN OF A SMOOTH SOLUTION FOR THE SURFACE DIFFUSION FLOW

Consider the motion of immersed hypersurfaces driven by surface diffusion flow and give anlower bound on the life span of a smooth immersed solution, which depends only on how muchthe curvature of the initial surface is concentrated in space.

EFFECTS OF TRANSVERSE OSCILLATIONS ON NATURAL CONVECTIVE FLOW INDUCED BY COMBINED THERMAL AND MASS DIFFUSIONS IN POROUS MEDIA

This paper studies the unsteady heat and mass natural convection in a highly porous medium bounded by an infinite vertical porous wall. The unsteady source of the problem arises from the transverse oscillations in suction velocity of fluids, The analytical results for the problem are obtained based on the method of small parameter, and show that the natural circulation in the porous medium is affected by this kind of oscillation.

Magnetic resonance imaging and cell-based neurorestorative therapy after brain injury

Restorative cell-based therapies for experimental brain injury, such as stroke and traumatic brain injury,substantially improve functional outcome. We discuss and review state of the art magnetic resonance imaging methodologies and their applications related to cell-based treatment after brain injury. We focus on the potential of magnetic resonance imaging technique and its associated challenges to obtain useful new information related to cell migration, distribution, and quantitation, as well as vascular and neuronal remodeling in response to cell-based therapy after brain injury. The noninvasive nature of imaging might more readily help with translation of cell-based therapy from the laboratory to the clinic.

Simulation and experimental investigation on a dynamic lateral flow mode in trepanning electrochemical machining

An appropriate flow mode of electrolyte has a positive effect on process efficiency, surface roughness, and machining accuracy in the electrochemical machining（ECM） process. In this study, a new dynamic lateral flow mode, in which the electrolyte flows from the leading edge to the trailing edge, was proposed in trepanning ECM of a diffuser. Then a numerical model of the channel was set up and simulated by using computational fluid dynamics software. The result showed that the distribution of the flow field was comparatively uniform in the inter-electrode gap. Furthermore, a fixture was designed to realize this new flow mode and then corresponding experiments were carried out. The experimental results illustrated that the feeding rate of the cathode reached 2 mm/min, the best taper angle was about 0.4°, and the best surface roughness was up to Ra= 0.115 lm. It reflects that this flow mode is suitable and effective, and can also be applied to machining other complex structures in trepanning ECM.

Turbulence modelling of the aerodynamic interaction ofOGV wakes and diffuser flow

Different turbulence closures were used to predict the flow interaction between the wakes created by compressor outlet guide vanes(OGVs) and a downstream annular pre-diffuser.Two statistical turbulence models were tested based on the classical Reynolds-averaged Navier-Stokes(RANS) approach.Both high-Re and low-Re(Launder-Sharma) versions of the k-ε model were applied to a selected test problem for OGV wake/diffuser flows.The test problem was specifically chosen because experimentally determined inlet conditions and both profile and performance data were available to validate predictions.A preliminary study was also reported of the more advanced large eddy simulation(LES) approach.The LES sub-grid-scale(SGS) model was the basic Smagorinsky eddy viscosity assumption,with a Van-Driest damping function for improved capture of near-wall viscous behaviour.Comparison between the two RANS models showed little difference in terms of velocity contours at OGV trailing edge and diffuser exit.In terms of overall diffuser performance(static pressure recovery and total pressure loss coefficients),the high-Re model was shown to agree well with experimental data.The preliminary LES study indicates the highly unsteady character of the OGV wake flow,but requires improved treatment of inlet conditions.

Simulation of flows with moving contact lines on a dual-resolution Cartesian grid using a diffuse-interface immersed-boundary method

In this paper, we investigate flows with moving contact lines on curved solid walls on a dual-resolution grid using a diffuse-interface immersed-boundary（DIIB） method. The dual-resolution grid, on which the flows are solved on a coarse mesh while the interface is resolved on a fine mesh, was shown to significantly improve the computational efficiency when simulating multiphase flows. On the other hand, the DIIB method is able to resolve dynamic wetting on curved substrates on a Cartesian grid, but it usually requires a mesh of high resolution in the vicinity of a moving contact line to resolve the local flow. In the present study, we couple the DIIB method with the dual-resolution grid, to improve the interface resolution for flows with moving contact lines on curved solid walls at an affordable cost. The dynamic behavior of moving contact lines is validated by studying drop spreading, and the numerical results suggest that the effective slip length λ_n can be approximated by 1.9Cn, where Cn is a dimensionless measure of the thickness of the diffuse interface. We also apply the method to drop impact onto a convex substrate, and the results on the dual-resolution grid are in good agreement with those on a single-resolution grid. It shows that the axisymmetric simulations using the DIIB method on the dual-resolution grid saves nearly 60% of the computational time compared with that on a single-resolution grid.

Navier-Stokes Computstions of the Supersonic Ejector Diffuser System with a Second Throat

The supersonic ejector-diffuser system with a second throat was simulated using CFD. An explicit finite volumescheme was aPPlied to solve tWo-dimensional Navier-Stokes equations with standard k - E tulbulence model. Thevacuum Performance of the supersonic ejector-diffuser system was investigated by changing the ejector throat arearatio and the operating Pressure ratio. Two convergent-divergent nozzles with design Mach nUmber of 2. 11 and 3.41were selected to give the supersonic operahon of the ejector-diffoser system. The presence of a second throat stronglyaffected the shock wave sir’UctUI’e inside the "dxing tube as well as the spreading of the under-expanded jetdischarging from the Primary nozzle. There were optimum values of the operating pressure ratio and ejector throatarea ratio for the vacuum performance of the system to maximize.

Experimental study of water and dissolved pollutant runoffs on impervious surfaces

The water and dissolved pollutant runoffs on impervious surfaces are the essential factor to be considered in design methods to minimize the impacts of the diffuse water pollution. In this paper, experiments are conducted to study the water and dissolved pollutant runoffs on impervious surfaces for different rainfall intensities and surface roughnesses. It is shown that a larger rainfall intensity and a smaller surface roughness reduce the time of concentration and increase the pollutant transport rate. Most of the pollutant runoffs take place at the initial stage of the rainfall. The pollutant transport rate rapidly reaches a peak and then gradually drops to zero.