Experimented data are presented for the void fraction aud the shear stresses of stratified gas-liquid flow in a pipe, A new technique was used to measure the interface shear strew. The interfacial shear stress was d...Experimented data are presented for the void fraction aud the shear stresses of stratified gas-liquid flow in a pipe, A new technique was used to measure the interface shear strew. The interfacial shear stress was determined by using two methods: a momentum balance of gas and an extrapolation of the Reynolds shear stress prone at the gas-liquld interface. A new formula ,relatiog to the interfacial friction factor with the void fraction and superficiol gas Rcynold number, was dewloped to predict the interface shear stress. The predicted values are in good agreement with experimental data.展开更多
The magnetohydrodynamics laws govern the motion of a conducting fluid, such as blood, in an externally applied static magnetic field B0. When an artery is exposed to a magnetic field, the blood charged particles are d...The magnetohydrodynamics laws govern the motion of a conducting fluid, such as blood, in an externally applied static magnetic field B0. When an artery is exposed to a magnetic field, the blood charged particles are deviated by the Lorentz force thus inducing electrical currents and voltages along the vessel walls and in the neighboring tissues. Such a situation may occur in several biomedical applications: magnetic resonance imaging (MRI), magnetic drug transport and targeting, tissue engineering… In this paper, we consider the steady unidirectional blood flow in a straight circular rigid vessel with non-conducting walls, in the presence of an exterior static magnetic field. The exact solution of Gold (1962) (with the induced fields not neglected) is revisited. It is shown that the integration over a cross section of the vessel of the longitudinal projection of the Lorentz force is zero, and that this result is related to the existence of current return paths, whose contributions compensate each other over the section. It is also demonstrated that the classical definition of the shear stresses cannot apply in this situation of magnetohydrodynamic flow, because, due to the existence of the Lorentz force, the axisymmetry is broken.展开更多
Infertility is often cited as one of the causes of a declining birthrate, which has become a serious social problem in recent years. Processes by which motile sperm can be safely and easily sorted are therefore import...Infertility is often cited as one of the causes of a declining birthrate, which has become a serious social problem in recent years. Processes by which motile sperm can be safely and easily sorted are therefore important for infertility treatment. Therefore, as a new sorting method, microfluidic sperm sorter using the microfluidic system has been developed. To improve more separation efficiency of this device, it is necessary to know the behaviors of motile sperm in the microchannel where the sperm undergo shear flow. The previous study implied the necessity of the modeling of motile sperm in the shear flow. In the present study, therefore, we experimentally investigated the behavior of the motile sperm in the Taylor-Couette flow using PTV (Particle Tracking Velocimetry) method. The experimental results showed that the ascent of the shear stress led to the increase in the sperm velocity, and the direction of the sperm velocity was opposite to that of the flow.展开更多
Inthis paper, each of the two phases in dense two-phase flow is considered as continuous medium and the fundamental equations for two-phase flow arc described in Eulerian form. The generalized constitutive relation of...Inthis paper, each of the two phases in dense two-phase flow is considered as continuous medium and the fundamental equations for two-phase flow arc described in Eulerian form. The generalized constitutive relation of the Bingham fluid is applied to the dispersed phase with the analysis oj physical mechanism of dense two-phase flow. The shearing stress of dispersed phase at a wall is used to give a boundary condition. Then a mathematical model for dense two-phase flow is obtained. In addition, the expressions of shearing stress of dispersed phase at a wall is derived according to the fundamental model of the friclional collision between dispersed-plutse particles and the wall.展开更多
Many in vitro studies focus on effects of wall shear stress (WSS) and wall shear stress gradient (WSSG) on endothelial cells, which are linked to the initiation and progression of atherosclerosis in the arterial syste...Many in vitro studies focus on effects of wall shear stress (WSS) and wall shear stress gradient (WSSG) on endothelial cells, which are linked to the initiation and progression of atherosclerosis in the arterial system. Limitation in available flow chambers with a constant WSSG in the testing region makes it difficult to quantify cellular responses to WSSG. The current study proposes and characterizes a type of converging parallel plate flow chamber (PPFC) featuring a constant gradient of WSS. A simple formula was derived for the curvature of side walls, which relates WSSG to flow rate (Q), height of the PPFC (h), length of the convergent section (L), its widths at the entrance (w0) and exit (w1). CFD simulation of flow in the chamber is carried out. Constant WSSG is observed in most regions of the top and bottom plates except those in close proximity of side walls. A change in Q or h induces equally proportional changes in WSS and WSSG whereas an alteration in the ratio between w0 and w1 results in a more significant change in WSSG than that in WSS. The current design makes possible an easy quantification of WSSG on endothelial cells in the flow chamber.展开更多
The aim of this paper is to provide an advanced analysis of the shear stresses exerted on vessel walls by the flowing blood, when a limb or the whole body, or a vessel prosthesis, a scaffold… is placed in an external...The aim of this paper is to provide an advanced analysis of the shear stresses exerted on vessel walls by the flowing blood, when a limb or the whole body, or a vessel prosthesis, a scaffold… is placed in an external static magnetic field B0. This type of situation could occur in several biomedical applications, such as magnetic resonance imaging (MRI), magnetic drug transport and targeting, tissue engineering, mechanotransduction studies… Since blood is a conducting fluid, its charged particles are deviated by the Hall effect, and the equations of motion include the Lorentz force. Consequently, the velocity profile is no longer axisymmetric, and the velocity gradients at the wall vary all around the vessel. To illustrate this idea, we expand the exact solution given by Gold (1962) for the stationary flow of blood in a rigid vessel with an insulating wall in the presence of an external static magnetic field: the analytical expressions for the velocity gradients are provided and evaluated near the wall. We demonstrate that the derivative of the longitudinal velocity with respect to the radial coordinate is preponderant when compared to the θ-derivative, and that elevated values of B0 would be required to induce some noteworthy influence on the shear stresses at the vessel wall.展开更多
AIM To investigate wall shear stress(WSS) magnitude and distribution in cirrhotic patients with portal hypertension using computational fluid dynamics. METHODS Idealized portal vein(PV) system models were reconstructe...AIM To investigate wall shear stress(WSS) magnitude and distribution in cirrhotic patients with portal hypertension using computational fluid dynamics. METHODS Idealized portal vein(PV) system models were reconstructed with different angles of the PV-splenic vein(SV) and superior mesenteric vein(SMV)-SV. Patient-specific models were created according to enhanced computed tomography images. WSS was simulated by using a finite-element analyzer, regarding the blood as a Newtonian fluid and the vessel as a rigid wall. Analysis was carried out to compare the WSSin the portal hypertension group with that in healthy controls.RESULTS For the idealized models, WSS in the portal hypertension group(0-10 dyn/cm2) was significantly lower than that in the healthy controls(10-20 dyn/cm2), and low WSS area(0-1 dyn/cm2) only occurred in the left wall of the PV in the portal hypertension group. Different angles of PV-SV and SMV-SV had different effects on the magnitude and distribution of WSS, and low WSS area often occurred in smaller PV-SV angle and larger SMV-SV angle. In the patient-specific models, WSS in the cirrhotic patients with portal hypertension(10.13 ± 1.34 dyn/cm2) was also significantly lower than that in the healthy controls(P < 0.05). Low WSS area often occurred in the junction area of SV and SMV into the PV, in the area of the division of PV into left and right PV, and in the outer wall of the curving SV in the control group. In the cirrhotic patients with portal hypertension, the low WSS area extended to wider levels and the magnitude of WSS reached lower levels, thereby being more prone to disturbed flow occurrence.CONCLUSION Cirrhotic patients with portal hypertension show dramatic hemodynamic changes with lower WSS and greater potential for disturbed flow, representing a possible causative factor of PV thrombosis.展开更多
The causes of local scour are generally categorized into flow condition, structure, and riverbed material. A three-dimensional vortex flow generated with the influence of the structure is the main factors of the flow ...The causes of local scour are generally categorized into flow condition, structure, and riverbed material. A three-dimensional vortex flow generated with the influence of the structure is the main factors of the flow conditions, and the size of the particles is assumed to be the main factor of the riverbed case. Various studies about pier local scour have been carried out by researchers since the 1960s, and a large number of experimental formulas have been suggested. Difficulties were encountered by these past studies, however, in terms of considering the influence of various riverbed materials and scour changes (floods, etc.) on time, with the condition of maximum scour depth. In the case of Korea, especially, scour influenced by various riverbed materials and the frequency of floods have been determined to be very important factors. Therefore, the ultimate purpose of this study on pier scour is to suggest the scour examination method that could consider various riverbed materials and the frequency of floods. In this study, the periodic changes in local scour based on the differences in the diameters of four types of bed materials, and on the hydraulic condition of the initial scour, were determined and compared with those in former studies. Using the results of the comparison, this study aims to determine the changes in the shear-stress around piers for various bed materials through the effect of time on scour depth (S, Smax), the shear-stress around piers, and the particles’ critical shear stress (τc).展开更多
The flow of incompressible couple stress fluid in a circular tube with stenosis and dilatations has been investigated. The stenosis was assumed to be axially symmetric and mild. The flow equations have been linearized...The flow of incompressible couple stress fluid in a circular tube with stenosis and dilatations has been investigated. The stenosis was assumed to be axially symmetric and mild. The flow equations have been linearized and the expressions for the resistance to the flow, velocity, pressure drop, wall shear stress have been derived. The effects of various parameters on these flow variables have been investigated. It is found that the resistance to the flow and pressure drop increase with height of the stenosis and decrease with post stenotic dilatation. Pressure drop decreases with couple stress fluid parameter for both stenosis and post stenotic dilatation. Further, the wall shear stress increases with height of the stenosis and couple stress parameter but decreases with post stenotic dilatation and couple stress fluid parameter.展开更多
The deflection angle of a river bend plays an important role on behaviours of the flow within it, and a clear understanding of the angle's influence is significant in both theoretical study and engineering applica...The deflection angle of a river bend plays an important role on behaviours of the flow within it, and a clear understanding of the angle's influence is significant in both theoretical study and engineering application. This paper presents a systematic numerical investigation on effects of deflection angles(30°, 60°, 90°, 120°, 150°, and 180°) on flow phenomena and their evolution in open-channel bends using a Re-Normalization Group(RNG) κ-ε model and a volume of fluid(VOF) method. The numerical results indicate that the deflection angle is a key factor for flows in bends. It is shown that the maximum transverse slope of water surface occurs at the middle cross section of a bend, and it increases with the deflection angle. Besides a major vortex, or, the primary circulation cell near the channel bottom, a secondary vortex, or, an outer bank cell, may also appear above the former and near the outer bank when the deflection angle is sufficiently large, and it will gradually migrate towards the inner bank and evolve into an inner bank cell. The strength of the secondary circulations increases with the deflection angle. The simulation demonstrates that there is alow-stress zone on the bed near the outer bank and a high-stress zone on the bed near the inner bank, and both of them increase in size with the deflection angle. The maximum of shear stress on the inner bank increases nonlinearly with the angle, and its maximums on the outer bank and on the bed take place when the deflection angle becomes 120°.展开更多
U-shaped micro-nanochannels can generate significant flow disturbance as well as locally amplified electric field, which gives itself potential to be microfluidic mixers, electrokinetic pumps,and even cell lysis proce...U-shaped micro-nanochannels can generate significant flow disturbance as well as locally amplified electric field, which gives itself potential to be microfluidic mixers, electrokinetic pumps,and even cell lysis process. Numerical simulation is utilized in this work to study the hidden characteristics of the U-shaped micro-nanochannel system, and the effects of key controlling parameters(the external voltage and pressure) on the device output metrics(current, maximum values of electric field, shear stress and flow velocity) were evaluated. A large portion of current flowing through the whole system goes through the nanochannels, rather than the middle part of the microchannel, with its value increasing linearly with the increase of voltage. Due to the local ion depletion near micro-nanofluidic junction, significantly enhanced electric field(as much as 15 fold at V=1 V and P_0=0) as well as strong shear stress(leading to electrokinetic flow) is generated.With increasing external pressure, both electric field and shear stress can be increased initially(due to shortening of depletion region length), but are suppressed eventually at higher pressure due to the destruction of ion depletion layer. Insights gained from this study could be useful for designing nonlinear electrokinetic pumps and other systems.展开更多
The three-dimensional （3D） lattice Boltzmann models, 3DQ15, 3DQ19 and 3DQ27, under different wall boundary conditions and lattice resolutions have been investigated by simulating Poiseuille flow in a circular cylind...The three-dimensional （3D） lattice Boltzmann models, 3DQ15, 3DQ19 and 3DQ27, under different wall boundary conditions and lattice resolutions have been investigated by simulating Poiseuille flow in a circular cylinder for a wide range of Reynolds numbers. The 3DQ19 model with improved Fillippova and Hanel （FH） curved boundary condition represents a good compromise between computational efficiency and reliability. Blood flow in an aortic arch is then simulated as a typical haemodynamic application. Axial and secondary fluid velocity and effective wall shear stress profiles in a 180° bend are obtained, and the results also demonstrate that the lattice Boltzmann method is suitable for simulating the flow in 3D large-curved vessels.展开更多
The parallel-plate flow chamber (PPFC), of which the height is far smaller than its own length and width, is one of the main apparatus for the in vitro study of the mechanical behaviors of cultured cells at the bottom...The parallel-plate flow chamber (PPFC), of which the height is far smaller than its own length and width, is one of the main apparatus for the in vitro study of the mechanical behaviors of cultured cells at the bottom of PPFC undergoing shear stress. The PPFC of which the upper and lower plates are rectangular is usually used by research workers, and the flow field in this kind of PPFC (except for the regions near the entrance and exit) is uniform([1]), so only the effect the shear stress with one value has on cultured cells can be observed during each experiment. A kind of PPFC of which the upper and lower plates are not rectangular is proposed in this paper. The distributions of the velocities inside and the shear stresses at the bottom of the chamber are given by analyzing the flow field of the steady flow in the PPFC. The results show that the mechanical behaviors of cultured cells undergoing the shear stresses with various values may be simultaneously observed by the use of this kind of irrectangular PPFC. The theoretical and experimental results obtained by Ultrasonic Doppler Technique show good agreement.展开更多
基金Supported by the National Natural Science Foundation of China(No.59236130).
文摘Experimented data are presented for the void fraction aud the shear stresses of stratified gas-liquid flow in a pipe, A new technique was used to measure the interface shear strew. The interfacial shear stress was determined by using two methods: a momentum balance of gas and an extrapolation of the Reynolds shear stress prone at the gas-liquld interface. A new formula ,relatiog to the interfacial friction factor with the void fraction and superficiol gas Rcynold number, was dewloped to predict the interface shear stress. The predicted values are in good agreement with experimental data.
文摘The magnetohydrodynamics laws govern the motion of a conducting fluid, such as blood, in an externally applied static magnetic field B0. When an artery is exposed to a magnetic field, the blood charged particles are deviated by the Lorentz force thus inducing electrical currents and voltages along the vessel walls and in the neighboring tissues. Such a situation may occur in several biomedical applications: magnetic resonance imaging (MRI), magnetic drug transport and targeting, tissue engineering… In this paper, we consider the steady unidirectional blood flow in a straight circular rigid vessel with non-conducting walls, in the presence of an exterior static magnetic field. The exact solution of Gold (1962) (with the induced fields not neglected) is revisited. It is shown that the integration over a cross section of the vessel of the longitudinal projection of the Lorentz force is zero, and that this result is related to the existence of current return paths, whose contributions compensate each other over the section. It is also demonstrated that the classical definition of the shear stresses cannot apply in this situation of magnetohydrodynamic flow, because, due to the existence of the Lorentz force, the axisymmetry is broken.
文摘Infertility is often cited as one of the causes of a declining birthrate, which has become a serious social problem in recent years. Processes by which motile sperm can be safely and easily sorted are therefore important for infertility treatment. Therefore, as a new sorting method, microfluidic sperm sorter using the microfluidic system has been developed. To improve more separation efficiency of this device, it is necessary to know the behaviors of motile sperm in the microchannel where the sperm undergo shear flow. The previous study implied the necessity of the modeling of motile sperm in the shear flow. In the present study, therefore, we experimentally investigated the behavior of the motile sperm in the Taylor-Couette flow using PTV (Particle Tracking Velocimetry) method. The experimental results showed that the ascent of the shear stress led to the increase in the sperm velocity, and the direction of the sperm velocity was opposite to that of the flow.
文摘Inthis paper, each of the two phases in dense two-phase flow is considered as continuous medium and the fundamental equations for two-phase flow arc described in Eulerian form. The generalized constitutive relation of the Bingham fluid is applied to the dispersed phase with the analysis oj physical mechanism of dense two-phase flow. The shearing stress of dispersed phase at a wall is used to give a boundary condition. Then a mathematical model for dense two-phase flow is obtained. In addition, the expressions of shearing stress of dispersed phase at a wall is derived according to the fundamental model of the friclional collision between dispersed-plutse particles and the wall.
文摘Many in vitro studies focus on effects of wall shear stress (WSS) and wall shear stress gradient (WSSG) on endothelial cells, which are linked to the initiation and progression of atherosclerosis in the arterial system. Limitation in available flow chambers with a constant WSSG in the testing region makes it difficult to quantify cellular responses to WSSG. The current study proposes and characterizes a type of converging parallel plate flow chamber (PPFC) featuring a constant gradient of WSS. A simple formula was derived for the curvature of side walls, which relates WSSG to flow rate (Q), height of the PPFC (h), length of the convergent section (L), its widths at the entrance (w0) and exit (w1). CFD simulation of flow in the chamber is carried out. Constant WSSG is observed in most regions of the top and bottom plates except those in close proximity of side walls. A change in Q or h induces equally proportional changes in WSS and WSSG whereas an alteration in the ratio between w0 and w1 results in a more significant change in WSSG than that in WSS. The current design makes possible an easy quantification of WSSG on endothelial cells in the flow chamber.
文摘The aim of this paper is to provide an advanced analysis of the shear stresses exerted on vessel walls by the flowing blood, when a limb or the whole body, or a vessel prosthesis, a scaffold… is placed in an external static magnetic field B0. This type of situation could occur in several biomedical applications, such as magnetic resonance imaging (MRI), magnetic drug transport and targeting, tissue engineering, mechanotransduction studies… Since blood is a conducting fluid, its charged particles are deviated by the Hall effect, and the equations of motion include the Lorentz force. Consequently, the velocity profile is no longer axisymmetric, and the velocity gradients at the wall vary all around the vessel. To illustrate this idea, we expand the exact solution given by Gold (1962) for the stationary flow of blood in a rigid vessel with an insulating wall in the presence of an external static magnetic field: the analytical expressions for the velocity gradients are provided and evaluated near the wall. We demonstrate that the derivative of the longitudinal velocity with respect to the radial coordinate is preponderant when compared to the θ-derivative, and that elevated values of B0 would be required to induce some noteworthy influence on the shear stresses at the vessel wall.
基金Supported by the Program for Changjiang Scholars and Innovative Research Team in Universities,No.PCSIRT-1171National Natural Science Foundation of China,No.81270504Fundamental Research Funds for the Central Universities,No.xjj20100209
文摘AIM To investigate wall shear stress(WSS) magnitude and distribution in cirrhotic patients with portal hypertension using computational fluid dynamics. METHODS Idealized portal vein(PV) system models were reconstructed with different angles of the PV-splenic vein(SV) and superior mesenteric vein(SMV)-SV. Patient-specific models were created according to enhanced computed tomography images. WSS was simulated by using a finite-element analyzer, regarding the blood as a Newtonian fluid and the vessel as a rigid wall. Analysis was carried out to compare the WSSin the portal hypertension group with that in healthy controls.RESULTS For the idealized models, WSS in the portal hypertension group(0-10 dyn/cm2) was significantly lower than that in the healthy controls(10-20 dyn/cm2), and low WSS area(0-1 dyn/cm2) only occurred in the left wall of the PV in the portal hypertension group. Different angles of PV-SV and SMV-SV had different effects on the magnitude and distribution of WSS, and low WSS area often occurred in smaller PV-SV angle and larger SMV-SV angle. In the patient-specific models, WSS in the cirrhotic patients with portal hypertension(10.13 ± 1.34 dyn/cm2) was also significantly lower than that in the healthy controls(P < 0.05). Low WSS area often occurred in the junction area of SV and SMV into the PV, in the area of the division of PV into left and right PV, and in the outer wall of the curving SV in the control group. In the cirrhotic patients with portal hypertension, the low WSS area extended to wider levels and the magnitude of WSS reached lower levels, thereby being more prone to disturbed flow occurrence.CONCLUSION Cirrhotic patients with portal hypertension show dramatic hemodynamic changes with lower WSS and greater potential for disturbed flow, representing a possible causative factor of PV thrombosis.
文摘The causes of local scour are generally categorized into flow condition, structure, and riverbed material. A three-dimensional vortex flow generated with the influence of the structure is the main factors of the flow conditions, and the size of the particles is assumed to be the main factor of the riverbed case. Various studies about pier local scour have been carried out by researchers since the 1960s, and a large number of experimental formulas have been suggested. Difficulties were encountered by these past studies, however, in terms of considering the influence of various riverbed materials and scour changes (floods, etc.) on time, with the condition of maximum scour depth. In the case of Korea, especially, scour influenced by various riverbed materials and the frequency of floods have been determined to be very important factors. Therefore, the ultimate purpose of this study on pier scour is to suggest the scour examination method that could consider various riverbed materials and the frequency of floods. In this study, the periodic changes in local scour based on the differences in the diameters of four types of bed materials, and on the hydraulic condition of the initial scour, were determined and compared with those in former studies. Using the results of the comparison, this study aims to determine the changes in the shear-stress around piers for various bed materials through the effect of time on scour depth (S, Smax), the shear-stress around piers, and the particles’ critical shear stress (τc).
文摘The flow of incompressible couple stress fluid in a circular tube with stenosis and dilatations has been investigated. The stenosis was assumed to be axially symmetric and mild. The flow equations have been linearized and the expressions for the resistance to the flow, velocity, pressure drop, wall shear stress have been derived. The effects of various parameters on these flow variables have been investigated. It is found that the resistance to the flow and pressure drop increase with height of the stenosis and decrease with post stenotic dilatation. Pressure drop decreases with couple stress fluid parameter for both stenosis and post stenotic dilatation. Further, the wall shear stress increases with height of the stenosis and couple stress parameter but decreases with post stenotic dilatation and couple stress fluid parameter.
基金supported by the National Natural Science Foundation of China(Grant No:51579162,51879174 and 51379137)the Open Funds of the State Key Laboratory of Hydraulics and Mountain River Engineering,Sichuan University(SKHL1301,SKHL1509)
文摘The deflection angle of a river bend plays an important role on behaviours of the flow within it, and a clear understanding of the angle's influence is significant in both theoretical study and engineering application. This paper presents a systematic numerical investigation on effects of deflection angles(30°, 60°, 90°, 120°, 150°, and 180°) on flow phenomena and their evolution in open-channel bends using a Re-Normalization Group(RNG) κ-ε model and a volume of fluid(VOF) method. The numerical results indicate that the deflection angle is a key factor for flows in bends. It is shown that the maximum transverse slope of water surface occurs at the middle cross section of a bend, and it increases with the deflection angle. Besides a major vortex, or, the primary circulation cell near the channel bottom, a secondary vortex, or, an outer bank cell, may also appear above the former and near the outer bank when the deflection angle is sufficiently large, and it will gradually migrate towards the inner bank and evolve into an inner bank cell. The strength of the secondary circulations increases with the deflection angle. The simulation demonstrates that there is alow-stress zone on the bed near the outer bank and a high-stress zone on the bed near the inner bank, and both of them increase in size with the deflection angle. The maximum of shear stress on the inner bank increases nonlinearly with the angle, and its maximums on the outer bank and on the bed take place when the deflection angle becomes 120°.
基金supported by the Intergovernmental International Science,Technology and Innovation Cooperation Key Project of the National Key R&D Programme(2016YFE0105900)the National Natural Science Foundation of China(21576130and 11372229)Kuwait Foundation for the Advancement of Sciences(Kuwait-MIT signature project,Project code:P31475EC01)
文摘U-shaped micro-nanochannels can generate significant flow disturbance as well as locally amplified electric field, which gives itself potential to be microfluidic mixers, electrokinetic pumps,and even cell lysis process. Numerical simulation is utilized in this work to study the hidden characteristics of the U-shaped micro-nanochannel system, and the effects of key controlling parameters(the external voltage and pressure) on the device output metrics(current, maximum values of electric field, shear stress and flow velocity) were evaluated. A large portion of current flowing through the whole system goes through the nanochannels, rather than the middle part of the microchannel, with its value increasing linearly with the increase of voltage. Due to the local ion depletion near micro-nanofluidic junction, significantly enhanced electric field(as much as 15 fold at V=1 V and P_0=0) as well as strong shear stress(leading to electrokinetic flow) is generated.With increasing external pressure, both electric field and shear stress can be increased initially(due to shortening of depletion region length), but are suppressed eventually at higher pressure due to the destruction of ion depletion layer. Insights gained from this study could be useful for designing nonlinear electrokinetic pumps and other systems.
基金Project supported by the National Natural Science Foundation of China(Grant No10274006)Education Ministry of China(Grant No03011)
文摘The three-dimensional （3D） lattice Boltzmann models, 3DQ15, 3DQ19 and 3DQ27, under different wall boundary conditions and lattice resolutions have been investigated by simulating Poiseuille flow in a circular cylinder for a wide range of Reynolds numbers. The 3DQ19 model with improved Fillippova and Hanel （FH） curved boundary condition represents a good compromise between computational efficiency and reliability. Blood flow in an aortic arch is then simulated as a typical haemodynamic application. Axial and secondary fluid velocity and effective wall shear stress profiles in a 180° bend are obtained, and the results also demonstrate that the lattice Boltzmann method is suitable for simulating the flow in 3D large-curved vessels.
文摘The parallel-plate flow chamber (PPFC), of which the height is far smaller than its own length and width, is one of the main apparatus for the in vitro study of the mechanical behaviors of cultured cells at the bottom of PPFC undergoing shear stress. The PPFC of which the upper and lower plates are rectangular is usually used by research workers, and the flow field in this kind of PPFC (except for the regions near the entrance and exit) is uniform([1]), so only the effect the shear stress with one value has on cultured cells can be observed during each experiment. A kind of PPFC of which the upper and lower plates are not rectangular is proposed in this paper. The distributions of the velocities inside and the shear stresses at the bottom of the chamber are given by analyzing the flow field of the steady flow in the PPFC. The results show that the mechanical behaviors of cultured cells undergoing the shear stresses with various values may be simultaneously observed by the use of this kind of irrectangular PPFC. The theoretical and experimental results obtained by Ultrasonic Doppler Technique show good agreement.
