The VEGF production by dedifferentiated chondrocytes under synovial fluid stimulation from coxarthrosis and femoral neck fracture patients

Objective To investigate the vascular endothelial growth factor(VEGF)expression level by chondrocytes isolated from patients with osteoarthritis (OA) in hip or femoral neck fracture (FNF) and explore the effect of synovial fluid from OA

Entropy Production Analysis for Hump Characteristics of a Pump Turbine Model

The hump characteristic is one of the main problems for the stable operation of pump turbines in pump mode.However,traditional methods cannot reflect directly the energy dissipation in the hump region.In this paper,3D simulations are carried out using the SST k-ω turbulence model in pump mode under different guide vane openings.The numerical results agree with the experimental data.The entropy production theory is introduced to determine the flow losses in the whole passage,based on the numerical simulation.The variation of entropy production under different guide vane openings is presented.The results show that entropy production appears to be a wave,with peaks under different guide vane openings,which correspond to wave troughs in the external characteristic curves.Entropy production mainly happens in the runner,guide vanes and stay vanes for a pump turbine in pump mode.Finally,entropy production rate distribution in the runner,guide vanes and stay vanes is analyzed for four points under the 18 mm guide vane opening in the hump region.The analysis indicates that the losses of the runner and guide vanes lead to hump characteristics.In addition,the losses mainly occur in the runner inlet near the band and on the suction surface of the blades.In the guide vanes and stay vanes,the losses come from pressure surface of the guide vanes and the wake effects of the vanes.A new insight-entropy production analysis is carried out in this paper in order to find the causes of hump characteristics in a pump turbine,and it could provide some basic theoretical guidance for the loss analysis of hydraulic machinery.

Pilot Test for Nitrogen Foam Flooding in Low Permeability Reservoir

Due to the characteristics of reservoir formation,the producing level of low permeability reservoir is relatively very low.It is hard to obtain high recovery through conventional development schemes.Considering the tight matrix,complex fracture system,low production level of producers,and low recovery factor ofMblock in Xinjiang oilfield,it is selected for on-site pilot test of nitrogen foam flooding.Detailed flooding scheme is made and the test results are evaluated respectively both for producers and injectors.The pressure index,filling degree,and fluid injection profile are found to be all improved in injectors after injection of nitrogen foam.The oil production,water cut and liquid production file are also improved in most of the producers,with the natural decline rate in the test area become slow.Results show that nitrogen foam flooding technology can be good technical storage for enhanced oil recovery in low permeability reservoir.