Elementary flux mode (EFM) analysis was used in the metabolic analysis of central carbon metabolism in Saccharomyces cerevisiae based on constructed cellular network. Calculated from the metabolic model, the ethanol...Elementary flux mode (EFM) analysis was used in the metabolic analysis of central carbon metabolism in Saccharomyces cerevisiae based on constructed cellular network. Calculated from the metabolic model, the ethanol-producing pathway No. 37 furthest converts the substrate into ethanol among the 78 elementary flux modes. The in silico metabolic phenotypes predicted based on this analysis fit well with the fermentation performance of the engineered strains, KAM3 and KAMll, which confirmed that EFM analysis is valid to direct the construction of Saccharomyces cerevisiae engineered strains, to increase the ethanol yield.展开更多
A gyrokinetic model with integral eigenmode equations is developed based on the local equilibrium of shaped tokamak plasmas. Effects of main geometric parameters (finite aspect ratio, elongation, triangularity, and S...A gyrokinetic model with integral eigenmode equations is developed based on the local equilibrium of shaped tokamak plasmas. Effects of main geometric parameters (finite aspect ratio, elongation, triangularity, and Shafranov shift gradient) on the electrostatic electron temper- ature gradient (ETG) driven modes are investigated numerically. It is found that the finite aspect ratio has a general stabilizing effect, while the elongation can be either stabilizing or destabilizing, depending on the poloidal wavelength of the mode and other parameters. It is shown that a low aspect ratio enhances the stabilizing effect of elongation, and weakens its destabilizing effect as well.展开更多
During El Niño events, the warm anomalies in the eastern tropical Pacific are seen to occur in conjunction with prominent warm anomalies in the North Pacific SSTs off the west coast of North America as well a...During El Niño events, the warm anomalies in the eastern tropical Pacific are seen to occur in conjunction with prominent warm anomalies in the North Pacific SSTs off the west coast of North America as well as with cold anomalies in the central North Pacific. This kind of North Pacific response to ENSO is examined in observational data and IPSL air-sea coupled model simulations. Analyses based on observational data and the model output data both support the hypothesis of an “atmospheric bridge concept”, i.e., the atmospheric response to ENSO, in turn, forces the extra-tropical SST anomalies associated with the El Ninno event, thereby serving as a bridge between the tropical and extra-tropical Pacific. Regarding the mechanism responsible for this, the ocean dynamical response to the atmospheric forcing is suggested to be active, while the contribution of latent heat flux is also significant. The role of solar radiation, longwave radiation, and sensible heat flux are of minor importance however, as indicated in the model. Further analysis shows that the North Pacific mode, which is linearly independent of ENSO, resembles the El Niño-type SST mode in the northern Pacific, i.e. both take the pattern of a zonally-oriented dipole in the subtropical Pacific, though differ slightly in the location of the anomaly center. The coupling between the North Pacific mode and the atmosphere is found to be mainly via air-sea heat flux exchange in the model. Both solar radiation and longwave radiation play important roles, while the contribution of latent heat flux is nearly negligible.展开更多
The ESMD method can be seen as a new alternate of the well-known Hilbert-Huang transform (HHT) for non-steady data processing. It is good at finding the optimal adaptive global mean fitting curve, which is superior to...The ESMD method can be seen as a new alternate of the well-known Hilbert-Huang transform (HHT) for non-steady data processing. It is good at finding the optimal adaptive global mean fitting curve, which is superior to the common least-square method and running-mean approach. Take the air-sea momentum flux investigation as an example, only when the non-turbulent wind components is well extracted, can the remainder signal be seen as actual oscillations caused by turbulence. With the aid of —5/3 power law for the turbulence, a mode-filtering approach based on ESMD decomposition is developed here. The test on observational data indicates that this approach is very feasible and it may greatly reduce the error caused by the non-turbulent components.展开更多
The phase of cross-correlation function of two different normal modes contains source range information, which can be extracted by warping transform due to the dispersive characteristics of the shallow water waveguide...The phase of cross-correlation function of two different normal modes contains source range information, which can be extracted by warping transform due to the dispersive characteristics of the shallow water waveguide. The autocorrelation function of the received pressure or particle velocity contains both modal autocorrelation component(MAC) and modal cross-correlation component(MCC), with the former part usually treated as interference for source ranging. Because the real part of the vertical intensity flux(RPVIF) only contains MCC, a passive impulsive source ranging method based on the frequency warping transform of RPVIF with a single vector receiver in shallow water is presented. Using a waveguide-invariant-based frequency warping operator, the cross-correlation components of two different modes in the vertical intensity flux are warped into separable impulsive sequences, the time delays of which are subsequently used for source ranging. The advantages of source ranging based on warping the vertical intensity flux compared with warping the pressure autocorrelation function are pointed out, and the experiment results are also presented.展开更多
Forward osmosis(FO), as an emerging technology, is influenced by different factors such as operating conditions,module characteristics, and membrane properties. The general aim of this study was to develop a suitable(...Forward osmosis(FO), as an emerging technology, is influenced by different factors such as operating conditions,module characteristics, and membrane properties. The general aim of this study was to develop a suitable(flexible,comprehensive, and convenient to use) computational tool which is able to simulate osmosis through an asymmetric membrane oriented in pressure retarded osmosis(PRO) mode in a wide variety of scenarios. For this purpose, an agent-based model was created in NetLogo platform, which is an easy-to-use application environment with graphical visualization abilities and well suited for modeling a complex system evolving over time. The simulation results were validated with empirical data obtained from literature and a great agreement was observed. The effect of various parameters on process performance was investigated in terms of temperature,cross-flow velocity, length of the module, pure water permeability coefficient, and structural parameter of the membrane. Results demonstrated that the increase in all parameters, except structural parameter of the membrane and the length of module led to the increase of average water flux. Moreover, nine different draw solutes were selected in order to assess the influence of net bulk osmotic pressure difference between the draw solution(DS) and feed solution(FS)(known as the driving force of FO process) on water flux. Based on the findings of this paper, the performance of FO process(PRO mode) can be efficiently evaluated using the NetL ogo platform.展开更多
针对数控机床永磁同步电机传统的线性磁链滑模观测器存在固有的抖振和不能在有限时间内收敛的问题,提出一种基于高阶终端滑模面的磁链滑模观测器(flux sliding mode observer based on high order terminal sliding mode surface,HOT-FS...针对数控机床永磁同步电机传统的线性磁链滑模观测器存在固有的抖振和不能在有限时间内收敛的问题,提出一种基于高阶终端滑模面的磁链滑模观测器(flux sliding mode observer based on high order terminal sliding mode surface,HOT-FSMO)。首先,将终端滑模因子引入滑模面,并用电流误差的导数取代了传统的线性部分,实现了状态变量误差在有限时间内全局收敛;其次,提出一种高阶滑模控制律,利用其传递函数的滤波特性,实现磁链估计的抖振抑制。仿真实验的结果表明,在不同转速和负载条件下,相比于传统的线性磁链滑模观测器,所提出的HOT-FSMO能够有效抑制定子电流估计值的抖振,减小位置估计误差,具有更强的鲁棒性;并且能够实现定子电流误差和磁链估计值在有限时间内收敛,加快了系统的响应速度,提高了系统的动态性能。展开更多
基金Supported by the National Natural Science Foundation of China (No.2002AA647040)
文摘Elementary flux mode (EFM) analysis was used in the metabolic analysis of central carbon metabolism in Saccharomyces cerevisiae based on constructed cellular network. Calculated from the metabolic model, the ethanol-producing pathway No. 37 furthest converts the substrate into ethanol among the 78 elementary flux modes. The in silico metabolic phenotypes predicted based on this analysis fit well with the fermentation performance of the engineered strains, KAM3 and KAMll, which confirmed that EFM analysis is valid to direct the construction of Saccharomyces cerevisiae engineered strains, to increase the ethanol yield.
基金National Natural Science Foundation of China(No.10405014)
文摘A gyrokinetic model with integral eigenmode equations is developed based on the local equilibrium of shaped tokamak plasmas. Effects of main geometric parameters (finite aspect ratio, elongation, triangularity, and Shafranov shift gradient) on the electrostatic electron temper- ature gradient (ETG) driven modes are investigated numerically. It is found that the finite aspect ratio has a general stabilizing effect, while the elongation can be either stabilizing or destabilizing, depending on the poloidal wavelength of the mode and other parameters. It is shown that a low aspect ratio enhances the stabilizing effect of elongation, and weakens its destabilizing effect as well.
基金This work was jointly supported by the Innovation Project of the Chinese Academy of Sciences (KZCX2- 108, ZKCX2-SW-210) and the National Key Progamme for Developing Basic Sciences (G200007850-2). Additional financial support from the National Natural Sci
文摘During El Niño events, the warm anomalies in the eastern tropical Pacific are seen to occur in conjunction with prominent warm anomalies in the North Pacific SSTs off the west coast of North America as well as with cold anomalies in the central North Pacific. This kind of North Pacific response to ENSO is examined in observational data and IPSL air-sea coupled model simulations. Analyses based on observational data and the model output data both support the hypothesis of an “atmospheric bridge concept”, i.e., the atmospheric response to ENSO, in turn, forces the extra-tropical SST anomalies associated with the El Ninno event, thereby serving as a bridge between the tropical and extra-tropical Pacific. Regarding the mechanism responsible for this, the ocean dynamical response to the atmospheric forcing is suggested to be active, while the contribution of latent heat flux is also significant. The role of solar radiation, longwave radiation, and sensible heat flux are of minor importance however, as indicated in the model. Further analysis shows that the North Pacific mode, which is linearly independent of ENSO, resembles the El Niño-type SST mode in the northern Pacific, i.e. both take the pattern of a zonally-oriented dipole in the subtropical Pacific, though differ slightly in the location of the anomaly center. The coupling between the North Pacific mode and the atmosphere is found to be mainly via air-sea heat flux exchange in the model. Both solar radiation and longwave radiation play important roles, while the contribution of latent heat flux is nearly negligible.
文摘The ESMD method can be seen as a new alternate of the well-known Hilbert-Huang transform (HHT) for non-steady data processing. It is good at finding the optimal adaptive global mean fitting curve, which is superior to the common least-square method and running-mean approach. Take the air-sea momentum flux investigation as an example, only when the non-turbulent wind components is well extracted, can the remainder signal be seen as actual oscillations caused by turbulence. With the aid of —5/3 power law for the turbulence, a mode-filtering approach based on ESMD decomposition is developed here. The test on observational data indicates that this approach is very feasible and it may greatly reduce the error caused by the non-turbulent components.
基金Project supported by the Frontier Science Research of Chinese Academy of Sciences(Grant No.QYZDY-SSW-SLH005)
文摘The phase of cross-correlation function of two different normal modes contains source range information, which can be extracted by warping transform due to the dispersive characteristics of the shallow water waveguide. The autocorrelation function of the received pressure or particle velocity contains both modal autocorrelation component(MAC) and modal cross-correlation component(MCC), with the former part usually treated as interference for source ranging. Because the real part of the vertical intensity flux(RPVIF) only contains MCC, a passive impulsive source ranging method based on the frequency warping transform of RPVIF with a single vector receiver in shallow water is presented. Using a waveguide-invariant-based frequency warping operator, the cross-correlation components of two different modes in the vertical intensity flux are warped into separable impulsive sequences, the time delays of which are subsequently used for source ranging. The advantages of source ranging based on warping the vertical intensity flux compared with warping the pressure autocorrelation function are pointed out, and the experiment results are also presented.
文摘Forward osmosis(FO), as an emerging technology, is influenced by different factors such as operating conditions,module characteristics, and membrane properties. The general aim of this study was to develop a suitable(flexible,comprehensive, and convenient to use) computational tool which is able to simulate osmosis through an asymmetric membrane oriented in pressure retarded osmosis(PRO) mode in a wide variety of scenarios. For this purpose, an agent-based model was created in NetLogo platform, which is an easy-to-use application environment with graphical visualization abilities and well suited for modeling a complex system evolving over time. The simulation results were validated with empirical data obtained from literature and a great agreement was observed. The effect of various parameters on process performance was investigated in terms of temperature,cross-flow velocity, length of the module, pure water permeability coefficient, and structural parameter of the membrane. Results demonstrated that the increase in all parameters, except structural parameter of the membrane and the length of module led to the increase of average water flux. Moreover, nine different draw solutes were selected in order to assess the influence of net bulk osmotic pressure difference between the draw solution(DS) and feed solution(FS)(known as the driving force of FO process) on water flux. Based on the findings of this paper, the performance of FO process(PRO mode) can be efficiently evaluated using the NetL ogo platform.
文摘针对数控机床永磁同步电机传统的线性磁链滑模观测器存在固有的抖振和不能在有限时间内收敛的问题,提出一种基于高阶终端滑模面的磁链滑模观测器(flux sliding mode observer based on high order terminal sliding mode surface,HOT-FSMO)。首先,将终端滑模因子引入滑模面,并用电流误差的导数取代了传统的线性部分,实现了状态变量误差在有限时间内全局收敛;其次,提出一种高阶滑模控制律,利用其传递函数的滤波特性,实现磁链估计的抖振抑制。仿真实验的结果表明,在不同转速和负载条件下,相比于传统的线性磁链滑模观测器,所提出的HOT-FSMO能够有效抑制定子电流估计值的抖振,减小位置估计误差,具有更强的鲁棒性;并且能够实现定子电流误差和磁链估计值在有限时间内收敛,加快了系统的响应速度,提高了系统的动态性能。