AIM : To evaluate the prediction error in intraocular lens(IOL) power calculation for a rotationally asymmetric refractive multifocal IOL and the impact on this error of the optimization of the keratometric estimation...AIM : To evaluate the prediction error in intraocular lens(IOL) power calculation for a rotationally asymmetric refractive multifocal IOL and the impact on this error of the optimization of the keratometric estimation of the corneal power and the prediction of the effective lens position(ELP).METHODS: Retrospective study including a total of 25 eyes of 13 patients(age, 50 to 83y) with previous cataract surgery with implantation of the Lentis Mplus LS-312 IOL(Oculentis Gmb H, Germany). In all cases, an adjusted IOL power(P IOLadj) was calculated based on Gaussian optics using a variable keratometric index value(n kadj) for the estimation of the corneal power(P kadj) and on a new value for ELP(ELP adj) obtained by multiple regression analysis.This P IOLadj was compared with the IOL power implanted(P IOLReal) and the value proposed by three conventional formulas(Haigis, Hoffer Q and Holladay Ⅰ).RESULTS: P IOLReal was not significantly different than P IOLadj and Holladay IOL power(P 】0.05). In the Bland and Altman analysis, P IOLadj showed lower mean difference(-0.07 D) and limits of agreement(of 1.47 and-1.61 D)when compared to P IOLReal than the IOL power value obtained with the Holladay formula. Furthermore, ELP adj was significantly lower than ELP calculated with other conventional formulas(P 【0.01) and was found to be dependent on axial length, anterior chamber depth and P kadj. CONCLUSION: Refractive outcomes after cataract surgery with implantation of the multifocal IOL Lentis Mplus LS-312 can be optimized by minimizing thekeratometric error and by estimating ELP using a mathematical expression dependent on anatomical factors.展开更多
AIM: To evaluate the effect of different lens constant optimization methods on the accuracy of intraocular lens(IOL) power calculation formulas for highly myopic eyes.METHODS: This study comprised 108 eyes of 94 conse...AIM: To evaluate the effect of different lens constant optimization methods on the accuracy of intraocular lens(IOL) power calculation formulas for highly myopic eyes.METHODS: This study comprised 108 eyes of 94 consecutive patients with axial length(AL) over 26 mm undergoing phacoemulsification and implantation of a Rayner(Hove, UK) 920H IOL. Formulas were evaluated using the following lens constants: manufacturer’s lens constant, User Group for Laser Interference Biometry(ULIB) constant, and optimized constant for long eyes. Results were compared with Barrett Universal II formula, original Wang-Koch AL adjustment method, and modified Wang-Koch AL adjustment method. The outcomes assessed were mean absolute error(MAE) and percentage of eyes with IOL prediction errors within ±0.25, ±0.50, and ±1.0 diopter(D). The nonparametric method, Friedman test, was used to compare MAE performance among constants.RESULTS: Optimized constants could significantly reduce the MAE of SRK/T, Hoffer Q, and Holladay 1 formulas compared with manufacturer’s lens constant, whereas the percentage of eyes with IOL prediction errors within ±0.25, ±0.50, and ±1.0 D had no statistically significant differences. Optimized lens constant for long eyes alone showed non-significant refractive advantages over the ULIB constant. Barrett Universal II formula and formulas with AL adjustment showed significantly higher accuracy in highly myopic eyes(P<0.001). CONCLUSION: Lens constant optimization for the subset of long eyes reduces the refractive error only to a limited extent for highly myopic eyes.展开更多
AIM: To evaluate changes in the anterior chamber depth (ACD), crystalline lens thickness (LT) and its refractive power after laser in situ keratomileusis (LASIK). METHODS: In all cases, the preoperative and postoperat...AIM: To evaluate changes in the anterior chamber depth (ACD), crystalline lens thickness (LT) and its refractive power after laser in situ keratomileusis (LASIK). METHODS: In all cases, the preoperative and postoperative central ACD which were measured with Pentacam, Orbscan, IOL-Master and A-scan ultrasonography, central corneal true net power which was measured with the Pentacam, Orbscan and IOL-Master, axial length (AL) which was measured with IOL-Master and LT which was measured with the A-scan ultrasonography were compared using the paired sample t test. Ocular refractive errors and lens refractive power at corneal plane were calculated and their correlations were also evaluated before and after LASIK. RESULTS: At 1 week after LASIK, LT and crystalline lens refractive power at corneal plane (Dlens) which were associated with the IOL-Master and Pentacam increased significantly (P <= 0.005), ACD decreased significantly (P <= 0.001), but no significant increase was observed in the Diens which was associated with the Orbscan(P=0.261). Significant correlations between the changes in the ocular refractive errors and Diens which were associated with the Pentacam were observed at 1 week and 6 months after LASIK (P = 0.028; P=0.001). CONCLUSION: LT increased significantly after LASIK, and this might partially lead to ACD decrease, Diens increase and a small quantity of myopic regression.展开更多
AIM: To evaluate the accuracy of three commonly used biometric formulae across different axial lengths(ALs) at one United States Veterans Affairs teaching hospital.METHODS: A retrospective chart review was conducted f...AIM: To evaluate the accuracy of three commonly used biometric formulae across different axial lengths(ALs) at one United States Veterans Affairs teaching hospital.METHODS: A retrospective chart review was conducted from November 2013 to May 2018. One eye of each patient who underwent cataract surgery with a monofocal intraocular lens(IOL) was included. The range of postoperative follow-up period was from 3 wk to 4 mo. The Holladay 2, Barrett Universal II, and Hill-Radial Basis Function(Hill-RBF) formulae were used to predict the postoperative refraction for all cataract surgeries. For each formula, we calculated the prediction errors [including mean absolute prediction error(MAE)] and the percentage of eyes within ±0.25 diopter(D) and ±0.5 D of predicted refraction. We performed subgroup analyses for short(AL<22.0 mm), medium(AL 22.0-25.0 mm), and long eyes(AL>25.0 mm).RESULTS: A total of 1131 patients were screened, and 909 met the inclusion criteria. Resident ophthalmologists were the primary surgeons in 710(78.1%) cases. We found no statistically significant difference in predictive accuracy among the three formulae over the entire AL range or in the short, medium, and long eye subgroups. Across the entire AL range, the Hill-RBF formula resulted in the lowest MAE(0.384 D) and the highest percentage of eyes with postoperative refraction within ±0.25 D(42.7%) and ±0.5 D(75.5%) of predicted. All three formulae had the highest MAEs(>0.5 D) and lowest percentage within ±0.5 D of predicted refraction(<55%) in short eyes.CONCLUSION: In cataract surgery patients at our teaching hospital, three commonly used biometric formulae demonstrate similar refractive accuracy across all ALs. Short eyes pose the greatest challenge to predicting postoperative refractive error.展开更多
Modeling and simulation have emerged as an indispensable approach to create numerical experiment platforms and study engineering systems.However,the increasingly complicated systems that engineers face today dramatica...Modeling and simulation have emerged as an indispensable approach to create numerical experiment platforms and study engineering systems.However,the increasingly complicated systems that engineers face today dramatically challenge state-of-the-art modeling and simulation approaches.Such complicated systems,which are composed of not only continuous states but also discrete events,and which contain complex dynamics across multiple timescales,are defined as generalized hybrid systems(GHSs)in this paper.As a representative GHS,megawatt power electronics(MPE)systems have been largely integrated into the modern power grid,but MPE simulation remains a bottleneck due to its unacceptable time cost and poor convergence.To address this challenge,this paper proposes the numerical convex lens approach to achieve state-discretized modeling and simulation of GHSs.This approach transforms conventional time-discretized passive simulations designed for pure-continuous systems into state-discretized selective simulations designed for GHSs.When this approach was applied to a largescale MPE-based renewable energy system,a 1000-fold increase in simulation speed was achieved,in comparison with existing software.Furthermore,the proposed approach uniquely enables the switching transient simulation of a largescale megawatt system with high accuracy,compared with experimental results,and with no convergence concerns.The numerical convex lens approach leads to the highly efficient simulation of intricate GHSs across multiple timescales,and thus significantly extends engineers’capability to study systems with numerical experiments.展开更多
AIM: To compare the Barrett True-K formula with other formulas integrated in Lenstar 900 to predict intraocular lens(IOL) power after small-incision lenticule extraction(SMILE).METHODS: A theoretical prospective study...AIM: To compare the Barrett True-K formula with other formulas integrated in Lenstar 900 to predict intraocular lens(IOL) power after small-incision lenticule extraction(SMILE).METHODS: A theoretical prospective study was performed to predict the ratio of equivalent IOL power before and after SMILE using the SRK/T(Sanders, Retzlaff, Kraff/theoretical), Holladay 1, Haigis, and Barrett True-K formulas and compare the stability of their predictions. The study included 54 eyes(54 cases) with a manifest refraction spherical equivalent(MRSE) of-4.99±1.45 D. They were divided into two groups: 27 eyes with axial length of 24-26 mm in Group A, and 27 eyes with axial length >26 mm in Group B. All subjects enrolled in this study were examined with the Lenstar 900 before and 6 mo after SMILE including measurements of axial length, corneal curvature, and anterior chamber depth(ACD). RESULTS: The prediction of equivalent IOL power of the two groups was more stable for the Barrett True-K formula, especially in long axial length eyes(Group B). The respective percentages for the SRK/T, Holladay 1, Haigis, and Barrett True-K formulas were 7.4%, 7.4%, 85.19%, and 88.89% for a margin of error within 0.5 D;25.92%, 51.84%, 100%, and 100% for a margin of error within 1.0 D in Group A;33.33%, 40.74%, 44.44%, and 81.48% for a margin of error within 0.5 D;and 44.44%, 59.26%, 66.66%, and 92.59% for a margin of error within 1.0 D in Group B. The respective percentages for Barrett True-K formulas were 100% for a margin of error within 2.0 D in Group B.CONCLUSION: Theoretically, the Barrett True-K formula provides more stable predictions than other formulas for cataract eyes after SMILE.展开更多
The output radiation from the 100μm×1μm aperture of a high power Laser Diode (LD) is efficiently coupled into a 50μm multimode optical fiber.The fiber output of the high power LD with high brightness and high ...The output radiation from the 100μm×1μm aperture of a high power Laser Diode (LD) is efficiently coupled into a 50μm multimode optical fiber.The fiber output of the high power LD with high brightness and high power density is achieved.The power density is up to 3 6×104W/cm2 and the coupling efficiency is 70%.The extreme divergence and the astigmatism of high power LDs require the optics with complex lens structures and high performance.A double-curved lens with two crossed cylindrical lenses structured on both sides of the glass substrate is used in the coupling system.展开更多
AIM:To investigate the binocular intraocular lens(IOL)power difference in eyes with short,normal,and long axial lengths(AL)using Lenstar LS 900 optical biometry.METHODS:A total of 716(1432 eyes)participants were inclu...AIM:To investigate the binocular intraocular lens(IOL)power difference in eyes with short,normal,and long axial lengths(AL)using Lenstar LS 900 optical biometry.METHODS:A total of 716(1432 eyes)participants were included.The groups were categorized into short(group A:AL<22 mm),normal(group B:22 mm≤AL≤25 mm),and long AL groups(group C:AL>25 mm).The central corneal thickness(CCT),anterior chamber depth(ACD),lens thickness(LT),AL,anterior corneal keratometry,whiteto-white(WTW),pupil diameter(PD),as well as IOL power calculated using embedded Barrett formula were assessed.Bland-Altman plots were used to test the agreement of the binocular parameters.RESULTS:In group A,the CCT of the right eye was significantly thinner than that of the left eye(P=0.044)with a difference of-2±8μm[95%limits of agreement(LoA),-17.8 to 13.2μm].For group B,the PD and IOL power in the right eye were significantly lower than those of the left eye(P=0.001,<0.001)with a difference of-0.05±0.32 mm(95%LoA,-0.68 to 0.58 mm)and-0.18±1.01 D(95%LoA,-2.2 to 1.8 D).The AL of right eye was longer than that of the left eye(P=0.002)with a difference of 0.04±0.25 mm(95%Lo A,-0.45 to 0.52 mm).No significant difference was observed for all the binocular parameters in group C.The percentage of participants with binocular IOL power difference within±0.5 D were 62%(31/50),68.3%(339/496),and 38.8%(66/170)in groups A,B,and C,respectively.CONCLUSION:The binocular parameters related to IOL power are in good agreement,but the binocular IOL power difference of more than half of participants with long AL is more than 0.50 D.展开更多
We demonstrated a robust power-scalable Kerr-lens mode-locked(KLM) operation based on a Yb:YAG thin-disk oscillator.15-W,272-fs pulses were realized at a repetition rate of 86.7 MHz with an additional Kerr medium a...We demonstrated a robust power-scalable Kerr-lens mode-locked(KLM) operation based on a Yb:YAG thin-disk oscillator.15-W,272-fs pulses were realized at a repetition rate of 86.7 MHz with an additional Kerr medium and a 2.5 mm hard aperture in the cavity.247-fs pulses with an average power of 11 W could also be obtained by using a 2.4 mm hard aperture.Based on this shorter pulse,high efficient second-harmonic generation(SHG) was performed with a 1.7-mm-long Li B3O5(LBO) crystal.The SHG laser power was up to 5 W with the power fluctuation RMS of 1% measured over one hour.展开更多
The effects of laser beam welding process parameters such as laser power,welding speed and focal position on mechanical properties and microstructure of AZ31B magnesium alloy were studied.Nine joints were fabricated u...The effects of laser beam welding process parameters such as laser power,welding speed and focal position on mechanical properties and microstructure of AZ31B magnesium alloy were studied.Nine joints were fabricated using different levels of laser power,welding speed and focal position.Tensile properties of the welded joints were evaluated and correlated with the weld zone microstructure and hardness.It is found that the joints fabricated using a laser power of 2 500 W,welding speed of 5.5 m/min and focal position of-1.5 mm yield superior tensile properties compared with the other joints.The formation of very fine grains in weld region,higher fusion zone hardness and uniformly distributed finer precipitates are the main reasons for superior tensile properties of these joints.展开更多
Non-orthogonal multiple access(NOMA)has been integrated in millimeter-wave(mmWave)Massive MIMO systems to further enhance the spectrum efficiency, but NOMA has not been fully considered in lens mmWave systems. The fus...Non-orthogonal multiple access(NOMA)has been integrated in millimeter-wave(mmWave)Massive MIMO systems to further enhance the spectrum efficiency, but NOMA has not been fully considered in lens mmWave systems. The fusion of these two technologies requires the joint design of beam selection and interference cancellation. In addition, when users follow the spatial cluster distribution, although the user clustering schemes based on K-means algorithm have been applied, the influence of the virtual and actual cluster center users on achievable sum rate has not been differentiated and analyzed in detail. To solve the above problems, a joint optimization scheme is proposed to maximize the achievable sum rate. The optimization problem is NP-hard, which is solved by using the divide-and-conquer approach. Concretely,based on the signal power loss analysis of directional deviation, a beam selection algorithm is designed for inter-cluster interference cancellation based on the Kmeans algorithm. Further for intra-cluster interference cancellation, a power allocation algorithm based on the bisection method is designed to guarantee the fairness of users in each cluster. The simulation results show that the proposed scheme offers a significant performance improvement in terms of both achievable sum rate and energy efficiency, and it is suitable for the large-scale user scenario due to its low complexity.展开更多
Backgrounds This paper introduces a polarized catadioptric virtual reality optical system.With a focus on the issue of serious ghost image in the system,root causes are analyzed based on design principles and optical ...Backgrounds This paper introduces a polarized catadioptric virtual reality optical system.With a focus on the issue of serious ghost image in the system,root causes are analyzed based on design principles and optical structure.Methods The distribution of stray light is simulated using Lighttools,and three major ghost paths are selected using the area of the diffuse spot,S d and the energy ratio of the stray light,K as evaluation means.A method to restrain the ghost image through optimization of the structure of the optical system by controlling the focal power of the ghost image path is proposed.Results/Conclusions The results show that the S_(d) for the ghost image path increases by 40%and K decreases by 40%after optimization.Ghost image is effectively suppressed,which provides the theoretical basis and technical support for ghost suppression in a virtual reality optical system.展开更多
A dish/stifling solar thermal electricity system consists of two parts: a dish solar concentrator and a Stifling engine. For optimizing the system, in this paper, the mathematical model for concentrator design was es...A dish/stifling solar thermal electricity system consists of two parts: a dish solar concentrator and a Stifling engine. For optimizing the system, in this paper, the mathematical model for concentrator design was established and the effects of those design parameters of concentrator, such as the size and intensity of the focal point, the receiver temperature, on the efficiency of the Stifling engine and output power were numerically simulated. The results of the simulation revealed a close relationship between power and efficiency because of power losses, and there was a maximum for the engine efficiency and power with increasing solar radiation because there was a peak value of system efficiency with increasing receiver temperature. So, in view of our Stifling engine, the 450 rim angle and 6m focal length are optimal design for concentrator and the 800℃receiver temperature is best.展开更多
Background:To investigate the associations of lens power with age,axial length(AL),and type 2 diabetes mellitus(DM)inChineseadultsaged5oandabove.Methods:Random clustering sampling was used to identify adults aged 50 y...Background:To investigate the associations of lens power with age,axial length(AL),and type 2 diabetes mellitus(DM)inChineseadultsaged5oandabove.Methods:Random clustering sampling was used to identify adults aged 50 years and above in urban regions of Shanghai.The participants underwent a comprehensive ophthalmic examination including subjective refraction,autorefraction,and IOL-Master.The crystalline lens power was calculated using Bennett's formula.Results:A total of 4177 adults were included.A linear decrease in lens power was observed both with age and with AL,followed by a stop of lens power loss after the age of 70 or when AL≥25 mm,respectively.Participants with type 2 DM presented higher lens power(0.43 diopter(D),P<0.001)and thicker lens thickness(0.06 mm,P<0.001).In multivariate regression models,there was a positive correlation between lens power and type 2 DM when age<75 years(P<0.001)or AL<25 mm(P<0.001)after adjusting for other factors,while no significant association was found in participants aged≥75 years(P=0.122)or with AL≥25 mm(P=0.172).Conclusions:The lens power in adults aged 50 and above exhibited two stages with age and with AL.Type 2 DM caused an increase in lens power,which was not seen in participants aged≥75 years or with AL≥25 mm.展开更多
Background:To investigate the associations of lens power with age,axial length(AL),and Type 2 diabetes mellitus(DM)in Chinese adults aged 50 and above.Methods:Random clustering sampling was used to identify adults age...Background:To investigate the associations of lens power with age,axial length(AL),and Type 2 diabetes mellitus(DM)in Chinese adults aged 50 and above.Methods:Random clustering sampling was used to identify adults aged 50 years and above in urban regions of Shanghai.The participants underwent a comprehensive ophthalmic examination including subjective refraction,autorefraction,and IOL-Master.The crystalline lens power was calculated using Bennett’s formula.Results:A total of 4177 adults were included.A linear decrease in lens power was observed both with age and with AL,followed by a stop of lens power loss after the age of 70 or when AL≥25 mm,respectively.Participants with Type 2 DM presented higher lens power(0.43 diopter(D),p<0.001)and thicker lens thickness(0.06 mm,p<0.001).In multivariate regression models,there was a positive correlation between lens power and Type 2 DM when age<75 years(p<0.001)or AL<25 mm(p<0.001)after adjusting for other factors,while no significant association was found in participants aged≥75 years(p=0.122)or with AL≥25 mm(p=0.172).Conclusions:The lens power in adults aged 50 and above exhibited two stages with age and with AL.Type 2 DM caused an increase in lens power,which was not seen in participants aged≥75 years or with AL≥25 mm.展开更多
Background:To examine the effectiveness of the use of machine learning for adapting an intraocular lens(IOL)power calculation for a patient group.Methods:In this retrospective study,the clinical records of 1,611 eyes ...Background:To examine the effectiveness of the use of machine learning for adapting an intraocular lens(IOL)power calculation for a patient group.Methods:In this retrospective study,the clinical records of 1,611 eyes of 1,169 Japanese patients who received a single model of monofocal IOL(SN60WF,Alcon)at Miyata Eye Hospital were reviewed and analyzed.Using biometric metrics and postoperative refractions of 1211 eyes of 769 patients,constants of the SRK/T and Haigis formulas were optimized.The SRK/T formula was adapted using a support vector regressor.Prediction errors in the use of adapted formulas as well as the SRK/T,Haigis,Hill-RBF and Barrett Universal II formulas were evaluated with data from 395 eyes of 395 distinct patients.Mean prediction errors,median absolute errors,and percentages of eyes within±0.25 D,±0.50 D,and±1.00 D,and over+0.50 D of errors were compared among formulas.Results:The mean prediction errors in the use of the SRT/K and adapted formulas were smaller than the use of other formulas(P<0.001).In the absolute errors,the Hill-RBF and adapted methods were better than others.The performance of the Barrett Universal II was not better than the others for the patient group.There were the least eyes with hyperopic refractive errors(16.5%)in the use of the adapted formula.Conclusions:Adapting IOL power calculations using machine learning technology with data from a particular patient group was effective and promising.展开更多
Background:To examine the effectiveness of the use of machine learning for adapting an intraocular lens(IOL)power calculation for a patient group.Methods:In this retrospective study,the clinical records of 1,611 eyes ...Background:To examine the effectiveness of the use of machine learning for adapting an intraocular lens(IOL)power calculation for a patient group.Methods:In this retrospective study,the clinical records of 1,611 eyes of 1,169 Japanese patients who received a single model of monofocal IOL(SN60WF,Alcon)at Miyata Eye Hospital were reviewed and analyzed.Using biometric metrics and postoperative refractions of 1211 eyes of 769 patients,constants of the SRK/T and Haigis formulas were optimized.The SRK/T formula was adapted using a support vector regressor.Prediction errors in the use of adapted formulas as well as the SRK/T,Haigis,Hill-RBF and Barrett Universal II formulas were evaluated with data from 395 eyes of 395 distinct patients.Mean prediction errors,median absolute errors,and percentages of eyes within±0.25 D,±0.50 D,and±1.00 D,and over+0.50 D of errors were compared among formulas.Results:The mean prediction errors in the use of the SRT/K and adapted formulas were smaller than the use of other formulas(P<0.001).In the absolute errors,the Hill-RBF and adapted methods were better than others.The performance of the Barrett Universal II was not better than the others for the patient group.There were the least eyes with hyperopic refractive errors(16.5%)in the use of the adapted formula.Conclusions:Adapting IOL power calculations using machine learning technology with data from a particular patient group was effective and promising.展开更多
文摘AIM : To evaluate the prediction error in intraocular lens(IOL) power calculation for a rotationally asymmetric refractive multifocal IOL and the impact on this error of the optimization of the keratometric estimation of the corneal power and the prediction of the effective lens position(ELP).METHODS: Retrospective study including a total of 25 eyes of 13 patients(age, 50 to 83y) with previous cataract surgery with implantation of the Lentis Mplus LS-312 IOL(Oculentis Gmb H, Germany). In all cases, an adjusted IOL power(P IOLadj) was calculated based on Gaussian optics using a variable keratometric index value(n kadj) for the estimation of the corneal power(P kadj) and on a new value for ELP(ELP adj) obtained by multiple regression analysis.This P IOLadj was compared with the IOL power implanted(P IOLReal) and the value proposed by three conventional formulas(Haigis, Hoffer Q and Holladay Ⅰ).RESULTS: P IOLReal was not significantly different than P IOLadj and Holladay IOL power(P 】0.05). In the Bland and Altman analysis, P IOLadj showed lower mean difference(-0.07 D) and limits of agreement(of 1.47 and-1.61 D)when compared to P IOLReal than the IOL power value obtained with the Holladay formula. Furthermore, ELP adj was significantly lower than ELP calculated with other conventional formulas(P 【0.01) and was found to be dependent on axial length, anterior chamber depth and P kadj. CONCLUSION: Refractive outcomes after cataract surgery with implantation of the multifocal IOL Lentis Mplus LS-312 can be optimized by minimizing thekeratometric error and by estimating ELP using a mathematical expression dependent on anatomical factors.
基金Supported by National Natural Science Foundation of China(No.81770905)
文摘AIM: To evaluate the effect of different lens constant optimization methods on the accuracy of intraocular lens(IOL) power calculation formulas for highly myopic eyes.METHODS: This study comprised 108 eyes of 94 consecutive patients with axial length(AL) over 26 mm undergoing phacoemulsification and implantation of a Rayner(Hove, UK) 920H IOL. Formulas were evaluated using the following lens constants: manufacturer’s lens constant, User Group for Laser Interference Biometry(ULIB) constant, and optimized constant for long eyes. Results were compared with Barrett Universal II formula, original Wang-Koch AL adjustment method, and modified Wang-Koch AL adjustment method. The outcomes assessed were mean absolute error(MAE) and percentage of eyes with IOL prediction errors within ±0.25, ±0.50, and ±1.0 diopter(D). The nonparametric method, Friedman test, was used to compare MAE performance among constants.RESULTS: Optimized constants could significantly reduce the MAE of SRK/T, Hoffer Q, and Holladay 1 formulas compared with manufacturer’s lens constant, whereas the percentage of eyes with IOL prediction errors within ±0.25, ±0.50, and ±1.0 D had no statistically significant differences. Optimized lens constant for long eyes alone showed non-significant refractive advantages over the ULIB constant. Barrett Universal II formula and formulas with AL adjustment showed significantly higher accuracy in highly myopic eyes(P<0.001). CONCLUSION: Lens constant optimization for the subset of long eyes reduces the refractive error only to a limited extent for highly myopic eyes.
文摘AIM: To evaluate changes in the anterior chamber depth (ACD), crystalline lens thickness (LT) and its refractive power after laser in situ keratomileusis (LASIK). METHODS: In all cases, the preoperative and postoperative central ACD which were measured with Pentacam, Orbscan, IOL-Master and A-scan ultrasonography, central corneal true net power which was measured with the Pentacam, Orbscan and IOL-Master, axial length (AL) which was measured with IOL-Master and LT which was measured with the A-scan ultrasonography were compared using the paired sample t test. Ocular refractive errors and lens refractive power at corneal plane were calculated and their correlations were also evaluated before and after LASIK. RESULTS: At 1 week after LASIK, LT and crystalline lens refractive power at corneal plane (Dlens) which were associated with the IOL-Master and Pentacam increased significantly (P <= 0.005), ACD decreased significantly (P <= 0.001), but no significant increase was observed in the Diens which was associated with the Orbscan(P=0.261). Significant correlations between the changes in the ocular refractive errors and Diens which were associated with the Pentacam were observed at 1 week and 6 months after LASIK (P = 0.028; P=0.001). CONCLUSION: LT increased significantly after LASIK, and this might partially lead to ACD decrease, Diens increase and a small quantity of myopic regression.
文摘AIM: To evaluate the accuracy of three commonly used biometric formulae across different axial lengths(ALs) at one United States Veterans Affairs teaching hospital.METHODS: A retrospective chart review was conducted from November 2013 to May 2018. One eye of each patient who underwent cataract surgery with a monofocal intraocular lens(IOL) was included. The range of postoperative follow-up period was from 3 wk to 4 mo. The Holladay 2, Barrett Universal II, and Hill-Radial Basis Function(Hill-RBF) formulae were used to predict the postoperative refraction for all cataract surgeries. For each formula, we calculated the prediction errors [including mean absolute prediction error(MAE)] and the percentage of eyes within ±0.25 diopter(D) and ±0.5 D of predicted refraction. We performed subgroup analyses for short(AL<22.0 mm), medium(AL 22.0-25.0 mm), and long eyes(AL>25.0 mm).RESULTS: A total of 1131 patients were screened, and 909 met the inclusion criteria. Resident ophthalmologists were the primary surgeons in 710(78.1%) cases. We found no statistically significant difference in predictive accuracy among the three formulae over the entire AL range or in the short, medium, and long eye subgroups. Across the entire AL range, the Hill-RBF formula resulted in the lowest MAE(0.384 D) and the highest percentage of eyes with postoperative refraction within ±0.25 D(42.7%) and ±0.5 D(75.5%) of predicted. All three formulae had the highest MAEs(>0.5 D) and lowest percentage within ±0.5 D of predicted refraction(<55%) in short eyes.CONCLUSION: In cataract surgery patients at our teaching hospital, three commonly used biometric formulae demonstrate similar refractive accuracy across all ALs. Short eyes pose the greatest challenge to predicting postoperative refractive error.
基金the Major Program of National Natural Science Foundation of China(51490683).
文摘Modeling and simulation have emerged as an indispensable approach to create numerical experiment platforms and study engineering systems.However,the increasingly complicated systems that engineers face today dramatically challenge state-of-the-art modeling and simulation approaches.Such complicated systems,which are composed of not only continuous states but also discrete events,and which contain complex dynamics across multiple timescales,are defined as generalized hybrid systems(GHSs)in this paper.As a representative GHS,megawatt power electronics(MPE)systems have been largely integrated into the modern power grid,but MPE simulation remains a bottleneck due to its unacceptable time cost and poor convergence.To address this challenge,this paper proposes the numerical convex lens approach to achieve state-discretized modeling and simulation of GHSs.This approach transforms conventional time-discretized passive simulations designed for pure-continuous systems into state-discretized selective simulations designed for GHSs.When this approach was applied to a largescale MPE-based renewable energy system,a 1000-fold increase in simulation speed was achieved,in comparison with existing software.Furthermore,the proposed approach uniquely enables the switching transient simulation of a largescale megawatt system with high accuracy,compared with experimental results,and with no convergence concerns.The numerical convex lens approach leads to the highly efficient simulation of intricate GHSs across multiple timescales,and thus significantly extends engineers’capability to study systems with numerical experiments.
文摘AIM: To compare the Barrett True-K formula with other formulas integrated in Lenstar 900 to predict intraocular lens(IOL) power after small-incision lenticule extraction(SMILE).METHODS: A theoretical prospective study was performed to predict the ratio of equivalent IOL power before and after SMILE using the SRK/T(Sanders, Retzlaff, Kraff/theoretical), Holladay 1, Haigis, and Barrett True-K formulas and compare the stability of their predictions. The study included 54 eyes(54 cases) with a manifest refraction spherical equivalent(MRSE) of-4.99±1.45 D. They were divided into two groups: 27 eyes with axial length of 24-26 mm in Group A, and 27 eyes with axial length >26 mm in Group B. All subjects enrolled in this study were examined with the Lenstar 900 before and 6 mo after SMILE including measurements of axial length, corneal curvature, and anterior chamber depth(ACD). RESULTS: The prediction of equivalent IOL power of the two groups was more stable for the Barrett True-K formula, especially in long axial length eyes(Group B). The respective percentages for the SRK/T, Holladay 1, Haigis, and Barrett True-K formulas were 7.4%, 7.4%, 85.19%, and 88.89% for a margin of error within 0.5 D;25.92%, 51.84%, 100%, and 100% for a margin of error within 1.0 D in Group A;33.33%, 40.74%, 44.44%, and 81.48% for a margin of error within 0.5 D;and 44.44%, 59.26%, 66.66%, and 92.59% for a margin of error within 1.0 D in Group B. The respective percentages for Barrett True-K formulas were 100% for a margin of error within 2.0 D in Group B.CONCLUSION: Theoretically, the Barrett True-K formula provides more stable predictions than other formulas for cataract eyes after SMILE.
文摘The output radiation from the 100μm×1μm aperture of a high power Laser Diode (LD) is efficiently coupled into a 50μm multimode optical fiber.The fiber output of the high power LD with high brightness and high power density is achieved.The power density is up to 3 6×104W/cm2 and the coupling efficiency is 70%.The extreme divergence and the astigmatism of high power LDs require the optics with complex lens structures and high performance.A double-curved lens with two crossed cylindrical lenses structured on both sides of the glass substrate is used in the coupling system.
基金Supported by the National Natural Science Foundation of China(No.81971697No.81501544)+1 种基金Shanxi Scholarship Council of China(No.2021-174)the Research Funding of Shanxi Eye Hospital(No.B201804)。
文摘AIM:To investigate the binocular intraocular lens(IOL)power difference in eyes with short,normal,and long axial lengths(AL)using Lenstar LS 900 optical biometry.METHODS:A total of 716(1432 eyes)participants were included.The groups were categorized into short(group A:AL<22 mm),normal(group B:22 mm≤AL≤25 mm),and long AL groups(group C:AL>25 mm).The central corneal thickness(CCT),anterior chamber depth(ACD),lens thickness(LT),AL,anterior corneal keratometry,whiteto-white(WTW),pupil diameter(PD),as well as IOL power calculated using embedded Barrett formula were assessed.Bland-Altman plots were used to test the agreement of the binocular parameters.RESULTS:In group A,the CCT of the right eye was significantly thinner than that of the left eye(P=0.044)with a difference of-2±8μm[95%limits of agreement(LoA),-17.8 to 13.2μm].For group B,the PD and IOL power in the right eye were significantly lower than those of the left eye(P=0.001,<0.001)with a difference of-0.05±0.32 mm(95%LoA,-0.68 to 0.58 mm)and-0.18±1.01 D(95%LoA,-2.2 to 1.8 D).The AL of right eye was longer than that of the left eye(P=0.002)with a difference of 0.04±0.25 mm(95%Lo A,-0.45 to 0.52 mm).No significant difference was observed for all the binocular parameters in group C.The percentage of participants with binocular IOL power difference within±0.5 D were 62%(31/50),68.3%(339/496),and 38.8%(66/170)in groups A,B,and C,respectively.CONCLUSION:The binocular parameters related to IOL power are in good agreement,but the binocular IOL power difference of more than half of participants with long AL is more than 0.50 D.
基金Project supported by the National Basic Research Program of China(Grant No.2013CB922402)the National Major Instrument Program of China(Grant No.2012YQ120047)the National Natural Science Foundation of China(Grant Nos.11434016 and 61210017)
文摘We demonstrated a robust power-scalable Kerr-lens mode-locked(KLM) operation based on a Yb:YAG thin-disk oscillator.15-W,272-fs pulses were realized at a repetition rate of 86.7 MHz with an additional Kerr medium and a 2.5 mm hard aperture in the cavity.247-fs pulses with an average power of 11 W could also be obtained by using a 2.4 mm hard aperture.Based on this shorter pulse,high efficient second-harmonic generation(SHG) was performed with a 1.7-mm-long Li B3O5(LBO) crystal.The SHG laser power was up to 5 W with the power fluctuation RMS of 1% measured over one hour.
文摘The effects of laser beam welding process parameters such as laser power,welding speed and focal position on mechanical properties and microstructure of AZ31B magnesium alloy were studied.Nine joints were fabricated using different levels of laser power,welding speed and focal position.Tensile properties of the welded joints were evaluated and correlated with the weld zone microstructure and hardness.It is found that the joints fabricated using a laser power of 2 500 W,welding speed of 5.5 m/min and focal position of-1.5 mm yield superior tensile properties compared with the other joints.The formation of very fine grains in weld region,higher fusion zone hardness and uniformly distributed finer precipitates are the main reasons for superior tensile properties of these joints.
基金supported by the National Natural Science Foundation of China (62001001)。
文摘Non-orthogonal multiple access(NOMA)has been integrated in millimeter-wave(mmWave)Massive MIMO systems to further enhance the spectrum efficiency, but NOMA has not been fully considered in lens mmWave systems. The fusion of these two technologies requires the joint design of beam selection and interference cancellation. In addition, when users follow the spatial cluster distribution, although the user clustering schemes based on K-means algorithm have been applied, the influence of the virtual and actual cluster center users on achievable sum rate has not been differentiated and analyzed in detail. To solve the above problems, a joint optimization scheme is proposed to maximize the achievable sum rate. The optimization problem is NP-hard, which is solved by using the divide-and-conquer approach. Concretely,based on the signal power loss analysis of directional deviation, a beam selection algorithm is designed for inter-cluster interference cancellation based on the Kmeans algorithm. Further for intra-cluster interference cancellation, a power allocation algorithm based on the bisection method is designed to guarantee the fairness of users in each cluster. The simulation results show that the proposed scheme offers a significant performance improvement in terms of both achievable sum rate and energy efficiency, and it is suitable for the large-scale user scenario due to its low complexity.
文摘Backgrounds This paper introduces a polarized catadioptric virtual reality optical system.With a focus on the issue of serious ghost image in the system,root causes are analyzed based on design principles and optical structure.Methods The distribution of stray light is simulated using Lighttools,and three major ghost paths are selected using the area of the diffuse spot,S d and the energy ratio of the stray light,K as evaluation means.A method to restrain the ghost image through optimization of the structure of the optical system by controlling the focal power of the ghost image path is proposed.Results/Conclusions The results show that the S_(d) for the ghost image path increases by 40%and K decreases by 40%after optimization.Ghost image is effectively suppressed,which provides the theoretical basis and technical support for ghost suppression in a virtual reality optical system.
文摘A dish/stifling solar thermal electricity system consists of two parts: a dish solar concentrator and a Stifling engine. For optimizing the system, in this paper, the mathematical model for concentrator design was established and the effects of those design parameters of concentrator, such as the size and intensity of the focal point, the receiver temperature, on the efficiency of the Stifling engine and output power were numerically simulated. The results of the simulation revealed a close relationship between power and efficiency because of power losses, and there was a maximum for the engine efficiency and power with increasing solar radiation because there was a peak value of system efficiency with increasing receiver temperature. So, in view of our Stifling engine, the 450 rim angle and 6m focal length are optimal design for concentrator and the 800℃receiver temperature is best.
基金This study was funded by the National Natural Science Foundation of China(Grant Nos.81670898 and 81703287)the Shanghai Three-Year Public Health Action Program(Project.Nos.GWIV-3.3 and GWIV-13.1)+6 种基金the Shanghai High-level Overseas Training Team Programon Eye Public Health(Project No.GWTD2015S08)the Shanghai Municipal Education Commission-Gaofeng Clinical Medicine Grant Support(Project No.20172022)the Shanghai General Hospital,Clinical Research(Project No.CTCCR-2018Z01)the Shanghai Science and Technology Commission Research Project(Project No.17ZR1426900)the Shanghai Municipal Planning Commission of Science and Research Fund(Project No.201640090)the National Key R&D Program of China(Project Nos.2016YFC0904800,2019YFC0840607)the National Science and Technology Major Project of China(Project No.2017ZX09304010).
文摘Background:To investigate the associations of lens power with age,axial length(AL),and type 2 diabetes mellitus(DM)inChineseadultsaged5oandabove.Methods:Random clustering sampling was used to identify adults aged 50 years and above in urban regions of Shanghai.The participants underwent a comprehensive ophthalmic examination including subjective refraction,autorefraction,and IOL-Master.The crystalline lens power was calculated using Bennett's formula.Results:A total of 4177 adults were included.A linear decrease in lens power was observed both with age and with AL,followed by a stop of lens power loss after the age of 70 or when AL≥25 mm,respectively.Participants with type 2 DM presented higher lens power(0.43 diopter(D),P<0.001)and thicker lens thickness(0.06 mm,P<0.001).In multivariate regression models,there was a positive correlation between lens power and type 2 DM when age<75 years(P<0.001)or AL<25 mm(P<0.001)after adjusting for other factors,while no significant association was found in participants aged≥75 years(P=0.122)or with AL≥25 mm(P=0.172).Conclusions:The lens power in adults aged 50 and above exhibited two stages with age and with AL.Type 2 DM caused an increase in lens power,which was not seen in participants aged≥75 years or with AL≥25 mm.
基金This study was funded by the National Natural Science Foundation of China(Grant No.:81670898 and 81703287,Beijing,China)the Shanghai Three-Year Public Health Action Program(Project Nos.GWIV-3.3 and GWIV-13.1,Shanghai,China)+7 种基金the Shanghai High-level Overseas Training Team Program on Eye Public Health(Project No.GWTD2015S08,Shanghai,China)Shanghai Municipal Education Commission—Gaofeng Clinical Medicine Grant Support(Project No.20172022,Shanghai,China)Shanghai General Hospital,Clinical Research(Project No.CTCCR-2018Z01,Shanghai,China)the Shanghai Science and Technology Commission Research Project(Project No.17ZR1426900,Shanghai,China)the Shanghai Municipal Planning Commission of Science and Research Fund(Project No.201640090,Shanghai,China)National Key R&D Program of China(Project No.2016YFC0904800,2019YFC0840607)National Science and Technology Major Project of China(Project No.2017ZX09304010)The sponsors or funding organizations had no role in the design or conduct of this research.
文摘Background:To investigate the associations of lens power with age,axial length(AL),and Type 2 diabetes mellitus(DM)in Chinese adults aged 50 and above.Methods:Random clustering sampling was used to identify adults aged 50 years and above in urban regions of Shanghai.The participants underwent a comprehensive ophthalmic examination including subjective refraction,autorefraction,and IOL-Master.The crystalline lens power was calculated using Bennett’s formula.Results:A total of 4177 adults were included.A linear decrease in lens power was observed both with age and with AL,followed by a stop of lens power loss after the age of 70 or when AL≥25 mm,respectively.Participants with Type 2 DM presented higher lens power(0.43 diopter(D),p<0.001)and thicker lens thickness(0.06 mm,p<0.001).In multivariate regression models,there was a positive correlation between lens power and Type 2 DM when age<75 years(p<0.001)or AL<25 mm(p<0.001)after adjusting for other factors,while no significant association was found in participants aged≥75 years(p=0.122)or with AL≥25 mm(p=0.172).Conclusions:The lens power in adults aged 50 and above exhibited two stages with age and with AL.Type 2 DM caused an increase in lens power,which was not seen in participants aged≥75 years or with AL≥25 mm.
文摘Background:To examine the effectiveness of the use of machine learning for adapting an intraocular lens(IOL)power calculation for a patient group.Methods:In this retrospective study,the clinical records of 1,611 eyes of 1,169 Japanese patients who received a single model of monofocal IOL(SN60WF,Alcon)at Miyata Eye Hospital were reviewed and analyzed.Using biometric metrics and postoperative refractions of 1211 eyes of 769 patients,constants of the SRK/T and Haigis formulas were optimized.The SRK/T formula was adapted using a support vector regressor.Prediction errors in the use of adapted formulas as well as the SRK/T,Haigis,Hill-RBF and Barrett Universal II formulas were evaluated with data from 395 eyes of 395 distinct patients.Mean prediction errors,median absolute errors,and percentages of eyes within±0.25 D,±0.50 D,and±1.00 D,and over+0.50 D of errors were compared among formulas.Results:The mean prediction errors in the use of the SRT/K and adapted formulas were smaller than the use of other formulas(P<0.001).In the absolute errors,the Hill-RBF and adapted methods were better than others.The performance of the Barrett Universal II was not better than the others for the patient group.There were the least eyes with hyperopic refractive errors(16.5%)in the use of the adapted formula.Conclusions:Adapting IOL power calculations using machine learning technology with data from a particular patient group was effective and promising.
文摘Background:To examine the effectiveness of the use of machine learning for adapting an intraocular lens(IOL)power calculation for a patient group.Methods:In this retrospective study,the clinical records of 1,611 eyes of 1,169 Japanese patients who received a single model of monofocal IOL(SN60WF,Alcon)at Miyata Eye Hospital were reviewed and analyzed.Using biometric metrics and postoperative refractions of 1211 eyes of 769 patients,constants of the SRK/T and Haigis formulas were optimized.The SRK/T formula was adapted using a support vector regressor.Prediction errors in the use of adapted formulas as well as the SRK/T,Haigis,Hill-RBF and Barrett Universal II formulas were evaluated with data from 395 eyes of 395 distinct patients.Mean prediction errors,median absolute errors,and percentages of eyes within±0.25 D,±0.50 D,and±1.00 D,and over+0.50 D of errors were compared among formulas.Results:The mean prediction errors in the use of the SRT/K and adapted formulas were smaller than the use of other formulas(P<0.001).In the absolute errors,the Hill-RBF and adapted methods were better than others.The performance of the Barrett Universal II was not better than the others for the patient group.There were the least eyes with hyperopic refractive errors(16.5%)in the use of the adapted formula.Conclusions:Adapting IOL power calculations using machine learning technology with data from a particular patient group was effective and promising.